WO1993014414A1 - Gradient field control - Google Patents
Gradient field control Download PDFInfo
- Publication number
- WO1993014414A1 WO1993014414A1 PCT/GB1993/000082 GB9300082W WO9314414A1 WO 1993014414 A1 WO1993014414 A1 WO 1993014414A1 GB 9300082 W GB9300082 W GB 9300082W WO 9314414 A1 WO9314414 A1 WO 9314414A1
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- WO
- WIPO (PCT)
- Prior art keywords
- field
- response
- windings
- gradient
- different
- Prior art date
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Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
- G01R33/00—Arrangements or instruments for measuring magnetic variables
- G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
- G01R33/28—Details of apparatus provided for in groups G01R33/44 - G01R33/64
- G01R33/38—Systems for generation, homogenisation or stabilisation of the main or gradient magnetic field
- G01R33/385—Systems for generation, homogenisation or stabilisation of the main or gradient magnetic field using gradient magnetic field coils
- G01R33/3852—Gradient amplifiers; means for controlling the application of a gradient magnetic field to the sample, e.g. a gradient signal synthesizer
Definitions
- the present invention relates to a method and apparatus for controlling the gradient field in an NMR apparatus. It is applicable to any type of NMR apparatus including superconducting, resistive electromagnetic or permanent magnetic systems.
- a main magnet is provided for generating a homogeneous steady axial field.
- a number of gradient coil sets are also provided. These superimpose gradients on the main field in order to localise a working volume of uniform magnetisation within the apparatus for investigation of the sample at that position.
- a pulse is applied to the gradient coils and the subsequent free induction decay (FID) signal from the sample is sensed.
- FID free induction decay
- the output of the coil would vary as a step function
- imperfections in the dynamic response of the gradient coils means that the shape of the output field pulse tends to be degraded.
- a large z 0 term equivalent to a time-varying shift in the main magnetic field B 0 , is generated as a result of eddy currents in the apparatus.
- a control system for a gradient field generator for use in an NMR apparatus including filter means arranged to modify a field demand signal so as to shape the gradient field profile, and current generators arranged to supply current to a plurality of individually magnetisable windings, in which the filter means include different filters corresponding to dynamic matric currents (I ⁇ I,) of different orders, and in which the outputs of the different filters are summed to provide the control input for one of the current generators, and subtracted to provide the control input for another of the current generators, the system thereby providing substantially decoupled control of a plurality of individually magnetisable windings.
- the method of the present invention provides decoupled control of the different fields orders using the combination of a number of individually magnetisable windings without requiring the use of any additional coils. This is achieved by decoupling the real current feeds for the windings into "dynamic matrix currents" corresponding to respectively even and odd order terms of the fields to be generated by the windings. Separate filters can then be provided for each of the matrix currents. The outputs of the different filters are then summed to give the current input for one winding and the difference taken to provide the current input for the other winding. In this manner the control system provides decoupled control of the different field orders.
- the method of the present invention can be applied to any type of magnet producing a DC field which has a gradient field superimposed. The actual form of the windings depends on the particular application and the preferred field strength, order of the field gradient, pulsed field profile, heating effects, and complexity of the power supply and control system.
- the plurality of windings comprise different parts of a single gradient coil.
- the different windings may be provided, for example, by the left and right parts of the axial (z) gradient coil or, for example, by the inner and outer parts of an x gradient coil or a y gradient coil.
- the different halves of such coils are readily accessed using centre taps.
- the sum of current inputs to the two parts of the winding (labelled A and B) produce odd order terms and these are used to generate the required z gradient.
- the difference windings of A and B produce even order terms and it is these which are used to compensate for the z 0 field shift.
- the nature of the physical connection to the different windings remains unchanged and "sum” or “difference" connections are effected by an appropriate change in the signs of the feeds to the respective windings.
- the filter means may comprise a number of discreet analogue filters with appropriately chosen time constants, or may be implemented by appropriate digital signal processing controlled by software.
- control system may further comprise a feedback loop arranged to sense a variation in a particular field order generated by the plurality of windings and to modify the corresponding matrix current accordingly.
- a further major advantage of the present invention is that by providing decoupling it makes it possible to construct feedback loops for individual field orders.
- the flux associated with a particular order can be measured from the induced EMF in the winding, or alternatively an equivalent search coil may be provided for this purpose.
- Other techniques having suitable dynamic response and sensitivity may be used.
- the feedback loop includes an AC coupled integrator.
- the integrator should be AC coupled. The filtering of the AC coupled integrator is then allowed for in the overall control strategy.
- a variety of different methods may be used to set the filter values for the control system but it is much preferred that this is done by measuring the frequency response of the system and calculating complementary response curves.
- the response curves may then be used directly to modify the feed signal in the case of a digitally implemented signal, or for a system using discrete analogue filters the time constants may be fitted to the curve using, e.g., a least-squares method. In either case, this approach avoids the inaccuracies resulting from attempting to identify eddy-current time constants. In the case of the directly digitally modified signal this method avoids altogether the need to identify filter time constants.
- This novel approach to determining values for the filters is not limited in application to control systems in accordance with the first aspect of the present invention but can also advantageously be used to determine the filter values for different types of feedforward control systems for gradient field generator windings.
- a method of determining the filter values for a feed forward control system for a gradient field generator for use in an NMR system comprising injecting currents into windings of the gradient field generator at a number of different frequencies, measuring the field strength at the different frequencies so as to determine response curves, calculating the inverses of the response matrix at the different frequencies, determining from the inverse values corresponding inverse response curves, and setting the filter means in the feed forward control system to give response characteristics substantially matched to the inverse response curves.
- the steps of injecting current at different frequencies and measuring the response may carried out directly on the control circuits or alternatively may be carried out using a computer model of the system, in which case the steps are implemented by equivalent mathematical operations.
- a method of controlling a gradient field generator for use in a NMR apparatus including determining response characteristics of the apparatus and modifying a field demand signal so as to compensate for the response characteristic, in which different elements of the matrix having dimensions corresponding to different orders of the field demand and different orders of the field response respectively are determined and the field demand signal is subsequently modified in accordance with the inverse of the matrix.
- the demand signal may be modified in accordance with the inverse matrix either by direct matrix inversion using filters corresponding to the elements of the inverted matrix, or by combining the use of filters with feed back of all cross-coupling terms.
- the filters are then in feed back loops and these loops cannot be guaranteed to be stable. In practice however in most instances especially when cross-coupling is modest, stability is possible.
- the filter network with feedback then responds exactly as the inverse matrix system.
- Figure la is a diagram showing schematically the transforming of matrix currents I 1 I 0 to the winding currents;
- Figure lb is a diagram showing the relationship between the matrix currents and the different field orders
- Figure lc shows the ideal inverse matrix compensation network
- Figure Id shows an alternative implementation of the matrix inversion using feedback
- Figure 2 is a circuit diagram for an analogue filter for use in the systems of Figure 1;
- Figures 3a - 3h are response curves for the system;
- Figures 4a - 4h are inverse response curves
- Figure 5 is a diagram showing a shielded gradient winding
- Figure 6 is a schematic showing the transfer function of a typical multiexponential filter
- Figures 7a and 7b are diagrams showing typical axial z gradient and axial x gradient coils respectively;
- Figure 8 is a circuit diagram and schematic of coil windings
- Figures 9a and 9b are a circuit diagram of a first printed circuit board used in the preferred embodiment
- Figures 10a and 10b are a circuit diagram of a second circuit board used in the preferred embodiment.
- Figure la shows schematically one example of a control system embodying the present invention.
- the system has an input 1 which receives a magnetic field demand signal.
- the demand signal contains only a first order term B,, since the required field response is a step function in the field gradient, without any change in the constant zeroth order field B 0 . Accordingly in practice the second demand input 1' would not be used unless required for a more general gradient control system.
- the demand signal is fed to a filter system 2.
- This comprises a first filter pair F 1 which provides an output which determines the first order matrix current I, and a second filter pair F 0 which provides the output determining the zeroth order matrix current I 0 .
- the sum of the outputs of F 1 and F 0 provide the control input to a first current amplifier 3A.
- the field generated by the windings does not perfectly track the rise in the applied current, but includes in addition time-varying fields resulting from eddy currents in the coils, and in other portions of the apparatus.
- the total field B generated in the system is related to the current I in the windings by a function G.
- the filters used to shape the field demand signal are arranged to have a response equivalent to G . Then, in the ideal case, the field generated by the windings perfectly tracks the demand signal.
- the magnetic field can be analysed in, say m g components (eg Legendre components Z,X,Y,XX, or fields at key points)
- the "j ⁇ " must be replaced for other transform (eg "s" for Laplace transform) .
- the current response may be determined from the demanded field as:
- the fields due to any section may be analysed by Legendre polynomials into coefficients of given orders (m,n) .
- the effective winding principle takes advantage of the separation of odd and even orders in the physically and electrically symmetrical A and B sections.
- Section B may have both signs inverted. It would then be the Difference that produces the "desired" orders.
- Section A ⁇ odd in m and/or n ⁇ + ⁇ even in m and or n ⁇
- Difference ⁇ even in m and/or n ⁇ [not desired]
- Tables la and lb show for the different orders of the Legendre polynomial expansion the contributions to the field of the A and B sections, together with the sum and difference of those contributions.
- Table la and the corresponding Figure 7a relate to a typical axial Z gradient
- Table lb relates to a typical transverse X gradient.
- Table la it can be seen that the difference windings produce large even order fields while the sum winding produces primarily the first order z field.
- the values for the different filters are determined by exciting the windings with matrix currents of different frequencies and measuring the frequency response. Different frequencies of 10 are injected and the strength of the resulting zeroth and first order fields measured, giving the response curves shown in Figures 3a and 3b respectively. Similarly different frequencies of II are injected and the zeroth and first order responses measured, giving plots 3c and 3d. At any given frequency these four plots correspond to a 2 x 2 matrix. These matrices are inverted to give the inverse response curves shown in Figures 4a to 4d.
- discreet filters are used, with the values of the filters chosen to approximate the inverse response curves by use of exponential fitting methods in the time domain, so that the filter has the same step response.
- Figure 6 shows a schematic for an analogue filter made up of the sum of a number of first order exponential filters.
- the FFT may be implemented using a discrete Fourier transform.
- the sample time for the transform must be less than the time constants of interest and the square wave must be of a long enough wavelength such that the slow time constants will have decayed.
- Plots f-j in Figures 3 and 4 show the response curves and inverse curves in the time domain.
- Figure 5 shows a shielded gradient winding in which a secondary winding is positioned outside the primary winding.
- the matrix currents may be combined in the primary and secondary windings in a number of different configurations, as shown in Table 2 which relates to an axial gradient. (In the sign convention chosen the current sense is equal to the axial field sense) .
- Table 2 which relates to an axial gradient.
- the primary and secondary coils are used to generate the B 0 field.
- Equivalent IA and IB can be produced by connecting the primary and secondary pairs in an uncrossed or crossed configuration.
- Option 1 shown in Figure 5 uses an uncrossed connection so that the real current in each of the secondaries is opposite in sign to that in the primary, thereby maintaining the active shielding.
- each block such as filter element .. in Figure 1 may be implemented by such a filter.
- the general form of the analogue filters can be represented by the sum of a DC component k 0 and the sum of exponential filters. In terms of Laplace transforms one gets:
- Figures 9 and 10 show in detail one example of a complete circuit incorporating the compensating filter. The different components of the circuit are described below. Because of the limited space available to mount the circuit, it is spread over two PCBs.
- the power input to the PCB is an unregulated +/- 23 volt supply.
- Integrated circuit U15 is a +15 volt regulator and together with CIO, C18, D5 and D7 supply +15 volt power to the circuit.
- U17 is a -15 volt regulator and together with Cll, C19, D6 and D8 provide the -15 volt power to the circuit.
- decoupling capacitor spread evenly about the two PCBs.
- the gradient demand input is a differential signal on connector PI alO and clO pins. A 5 volt level between these two pins will constitute a maximum gradient demand.
- Integrated circuit Ul receives this signal and this is summed with the shim demand by U3.
- Test Point 6 is a monitor point that is the sum of both the gradient demand and the shim demand.
- the shim demand input on connector PI pins al4 and al5 is received by the differential amplifier U2. This signal is then limited in frequency by the low pass filter R9 and
- the BO compensation circuits are similar to the cross term circuits.
- the demand for the BO circuit is only the uncompensated DEMAND signal.
- U8a forms a signal that is linearly proportional to the DEMAND signal with a gain set by RV25 between -1 and +1.
- the four circuits associated with C9 to C12 are similar to the cross term circuits described above.
- Circuit U10 sums each of the five BO compensation signals at TP9 to TP12 and TP15. Each compensation is a maximum of +/- 10% of the DEMAND signal.
- the three signals CT1_0UT, CT2_OUT and B0_0UT are presented to the connector PI pins cl6, cl7, c3 respectively and passed on the amplifier control circuits to drive the required gradient coils.
- the demand signal When driving an inductive load the demand signal has to be rise time limited to keep the output voltage of the amplifier within its working range.
- the circuit combination of U4 and U5 generate a linear ramp on the rising and falling edges of the demand signal.
- the slew rate limit is adjusted by the RV2 potentiometer over a range of 0.1 millisecond to over 1 millisecond of time to full demand.
- eddy current compensation is required to get the optimum performance from a MRI system. Depending on the exact requirements of the system this compensation may be required to pre-emphasize or de- emphasize the current demand.
- the modification is constructed with four available time constants made from four independent circuits associated with capacitors CI, C2, C3 and C4. Each time constant is adjusted with potentiometers RV3, RV5, RV7 and RV9 respectively. The time constants are buffered by U6a, U6b, U7a and U7b. The gain of each time constant can be varied from -1 to +1 with potentiometers RV4, RV6, RV8 and RV10 respectively. Each of the four compensation signals can be monitored on test points TP9, TP10, TPll and TP12. Cross Term Demands
- CR_DEM is the same signal as the gradient demand output and contains all of the compensation signals as programmed.
- the demand output presented to connector PI cl and monitored on TP17 is the sum of the demand input, shim input and any combination of eddy current compensation and cross term combination required.
- Links LK5 to LK16 together with the adjustment potentiometers are used to program the desired compensation signal.
- the gradient amplifier may be able to deliver larger power than the gradient coil can withstand.
- a protection circuit is incorporated to monitor the gradient demand signal and to set the amplifier into standby mode if the demand is higher than a set level.
- Circuit U9, U10 and the associated components form a precision rectifier
- TP6 signal is the absolute value of the demand signal.
- Ull is a transconductance amplifier that is used as a squarer circuit its output is the square of the demand signal.
- the signal at TP14 is proportional to the square of the output current. This signal level is monitored by the level detector U13. If the TP14 signal becomes more +ve than the level set at TP15 by RVll then the TP15 signal and connector Pi pin c20 goes to a low (0 volt) level and sets the amplifier in the STANDBY state.
- the "piggy back" board contains eight cross term circuits in two sets of four. Each of the eight circuits is identical except for the value of the compensation capacitors Cl to C8.
- the links LK27 and LK28 select which of the two demand signals are required for the cross compensation. Either the uncompensated DEMAND signal is selected with LK27 or the compensated output demand CR_DEM with LK28.
- the time constant is set by the Cl, RVl combination and is buffered by Ulb.
- RV2 sets the compensation gain between -1 and +1.
- the circuit associated with U7 sums the four compensation signals at TP1 to TP4.
- the required compensation being selected by the links LK1 to LK8.
- TP13 forms the first cross term signal CT1_0UT.
- Each of the compensation circuits can be set to a maximum of +/- 10% of the demand signal.
- CT2_OUT the compensation is set with C5 to C8 and RV9 to RV15 components, U8 sums the signals from TP5 to TP8, links LK9 to LK16 select the desired compensation signals.
- one preferred aspect of the present invention uses feedback based on NMR measurements.
- the NMR response from a known sample volume is measured across an array of many sampling points.
- the response is compared with the expected response to derive an error signal which is used in the feedback loop to modify the matrix currents.
Abstract
Description
Claims
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP5512284A JPH07502671A (en) | 1992-01-15 | 1993-01-15 | gradient field control |
EP93901871A EP0621955A1 (en) | 1992-01-15 | 1993-01-15 | Gradient field control |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB9200812.7 | 1992-01-15 | ||
GB929200812A GB9200812D0 (en) | 1992-01-15 | 1992-01-15 | Gradient field control |
Publications (1)
Publication Number | Publication Date |
---|---|
WO1993014414A1 true WO1993014414A1 (en) | 1993-07-22 |
Family
ID=10708629
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/GB1993/000082 WO1993014414A1 (en) | 1992-01-15 | 1993-01-15 | Gradient field control |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP0621955A1 (en) |
JP (1) | JPH07502671A (en) |
AU (1) | AU3265093A (en) |
GB (1) | GB9200812D0 (en) |
WO (1) | WO1993014414A1 (en) |
Cited By (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2001038893A2 (en) * | 1999-11-19 | 2001-05-31 | Koninklijke Philips Electronics N.V. | Mri apparatus with a feed forward loop inserted in the gradient loop |
WO2004070412A1 (en) * | 2003-02-05 | 2004-08-19 | Koninklijke Philips Electronics N.V. | Compensation of magnetic field disturbances due to vibrations in an mri system |
WO2005091010A1 (en) * | 2004-03-16 | 2005-09-29 | Koninklijke Philips Electronics N.V. | Magnetic resonance imaging device bwith an active shielding device |
US7319326B2 (en) | 2004-09-23 | 2008-01-15 | University Of New Brunswick | Sensor and magnetic field apparatus suitable for use in for unilateral nuclear magnetic resonance and method for making same |
US8237440B2 (en) | 2005-09-23 | 2012-08-07 | University Of New Brunswick | Magnetic field generator suitable for unilateral nuclear magnetic resonance and method for making same |
US8593144B2 (en) | 2006-11-24 | 2013-11-26 | University Of New Brunswick | Magnet array |
RU2504794C2 (en) * | 2008-07-11 | 2014-01-20 | Конинклейке Филипс Электроникс Н.В. | Digital amplifier with control using direct and feedback links |
WO2015020729A1 (en) | 2013-08-06 | 2015-02-12 | Linear Research Associates, Inc. | Adjustable compensation ratio feedback system |
Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4437053A (en) * | 1982-05-10 | 1984-03-13 | Diasonics (Nmr) Inc. | Gradient power supply |
US4585995A (en) * | 1984-04-19 | 1986-04-29 | Technicare Corporation | Nuclear magnetic resonance eddy field suppression apparatus |
EP0291157A2 (en) * | 1987-04-03 | 1988-11-17 | Picker International, Inc. | Eddy current correction in magnetic resonance apparatus and methods |
EP0361574A1 (en) * | 1988-09-08 | 1990-04-04 | Koninklijke Philips Electronics N.V. | Method of and device for eddy current compensation in MR apparatus |
US4928063A (en) * | 1987-11-09 | 1990-05-22 | Picker International, Inc. | Automatic eddy current correction |
DE4020213A1 (en) * | 1990-06-25 | 1992-01-09 | Siemens Ag | INDIRECT MEASUREMENT AND CONTROL OF THE MAGNETIC GRADIENT FIELD OF A NUCLEAR RESONANCE IMAGING SYSTEM |
EP0476321A1 (en) * | 1990-09-20 | 1992-03-25 | Siemens Aktiengesellschaft | Nuclear spin tomograph |
-
1992
- 1992-01-15 GB GB929200812A patent/GB9200812D0/en active Pending
-
1993
- 1993-01-15 EP EP93901871A patent/EP0621955A1/en not_active Withdrawn
- 1993-01-15 WO PCT/GB1993/000082 patent/WO1993014414A1/en not_active Application Discontinuation
- 1993-01-15 AU AU32650/93A patent/AU3265093A/en not_active Abandoned
- 1993-01-15 JP JP5512284A patent/JPH07502671A/en active Pending
Patent Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4437053A (en) * | 1982-05-10 | 1984-03-13 | Diasonics (Nmr) Inc. | Gradient power supply |
US4585995A (en) * | 1984-04-19 | 1986-04-29 | Technicare Corporation | Nuclear magnetic resonance eddy field suppression apparatus |
EP0291157A2 (en) * | 1987-04-03 | 1988-11-17 | Picker International, Inc. | Eddy current correction in magnetic resonance apparatus and methods |
US4928063A (en) * | 1987-11-09 | 1990-05-22 | Picker International, Inc. | Automatic eddy current correction |
EP0361574A1 (en) * | 1988-09-08 | 1990-04-04 | Koninklijke Philips Electronics N.V. | Method of and device for eddy current compensation in MR apparatus |
DE4020213A1 (en) * | 1990-06-25 | 1992-01-09 | Siemens Ag | INDIRECT MEASUREMENT AND CONTROL OF THE MAGNETIC GRADIENT FIELD OF A NUCLEAR RESONANCE IMAGING SYSTEM |
EP0476321A1 (en) * | 1990-09-20 | 1992-03-25 | Siemens Aktiengesellschaft | Nuclear spin tomograph |
Non-Patent Citations (1)
Title |
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JOURNAL OF MAGNETIC RESONANCE. vol. 90, no. 2, 1 November 1990, ORLANDO, MN US pages 264 - 278 P. JEHENSON ET AL. 'ANALYTICAL METHOD FOR THE COMPENSATION OF EDDY-CURRENT EFFECTS INDUCED BY PULSED MAGNETIC FIELD GRADIENTS IN NMR SYSTEMS' cited in the application * |
Cited By (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2001038893A2 (en) * | 1999-11-19 | 2001-05-31 | Koninklijke Philips Electronics N.V. | Mri apparatus with a feed forward loop inserted in the gradient loop |
WO2001038893A3 (en) * | 1999-11-19 | 2002-03-28 | Koninkl Philips Electronics Nv | Mri apparatus with a feed forward loop inserted in the gradient loop |
WO2004070412A1 (en) * | 2003-02-05 | 2004-08-19 | Koninklijke Philips Electronics N.V. | Compensation of magnetic field disturbances due to vibrations in an mri system |
US7372265B2 (en) | 2003-02-05 | 2008-05-13 | Koninklijke Philips Electronics N.V. | Compensation of magnetic field disturbances due to vibrations in an MRI system |
WO2005091010A1 (en) * | 2004-03-16 | 2005-09-29 | Koninklijke Philips Electronics N.V. | Magnetic resonance imaging device bwith an active shielding device |
US7319326B2 (en) | 2004-09-23 | 2008-01-15 | University Of New Brunswick | Sensor and magnetic field apparatus suitable for use in for unilateral nuclear magnetic resonance and method for making same |
US8237440B2 (en) | 2005-09-23 | 2012-08-07 | University Of New Brunswick | Magnetic field generator suitable for unilateral nuclear magnetic resonance and method for making same |
US8593144B2 (en) | 2006-11-24 | 2013-11-26 | University Of New Brunswick | Magnet array |
RU2504794C2 (en) * | 2008-07-11 | 2014-01-20 | Конинклейке Филипс Электроникс Н.В. | Digital amplifier with control using direct and feedback links |
WO2015020729A1 (en) | 2013-08-06 | 2015-02-12 | Linear Research Associates, Inc. | Adjustable compensation ratio feedback system |
EP3030915A4 (en) * | 2013-08-06 | 2017-07-12 | Linear Research Associates, Inc. | Adjustable compensation ratio feedback system |
Also Published As
Publication number | Publication date |
---|---|
EP0621955A1 (en) | 1994-11-02 |
AU3265093A (en) | 1993-08-03 |
JPH07502671A (en) | 1995-03-23 |
GB9200812D0 (en) | 1992-03-11 |
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