WO1993008752A1 - Method of thawing cryosurgical apparatus - Google Patents
Method of thawing cryosurgical apparatus Download PDFInfo
- Publication number
- WO1993008752A1 WO1993008752A1 PCT/GB1992/002030 GB9202030W WO9308752A1 WO 1993008752 A1 WO1993008752 A1 WO 1993008752A1 GB 9202030 W GB9202030 W GB 9202030W WO 9308752 A1 WO9308752 A1 WO 9308752A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- gas
- probe
- cryogen
- thawing
- supply
- Prior art date
Links
- 238000000034 method Methods 0.000 title claims abstract description 21
- 238000010257 thawing Methods 0.000 title claims abstract description 12
- 239000000523 sample Substances 0.000 claims abstract description 34
- 239000007789 gas Substances 0.000 claims abstract description 17
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims abstract description 15
- 229910052757 nitrogen Inorganic materials 0.000 claims abstract description 7
- 239000011261 inert gas Substances 0.000 claims abstract description 5
- 239000012530 fluid Substances 0.000 claims description 3
- 238000010438 heat treatment Methods 0.000 claims description 3
- 238000007710 freezing Methods 0.000 abstract description 4
- 230000008014 freezing Effects 0.000 abstract description 4
- 239000007788 liquid Substances 0.000 description 3
- 230000015572 biosynthetic process Effects 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 229910001873 dinitrogen Inorganic materials 0.000 description 1
- 238000010348 incorporation Methods 0.000 description 1
- 238000012544 monitoring process Methods 0.000 description 1
- 238000010926 purge Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/02—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00005—Cooling or heating of the probe or tissue immediately surrounding the probe
- A61B2018/00041—Heating, e.g. defrosting
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
- F25D—REFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
- F25D21/00—Defrosting; Preventing frosting; Removing condensed or defrost water
- F25D21/06—Removing frost
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
- F25D—REFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
- F25D3/00—Devices using other cold materials; Devices using cold-storage bodies
- F25D3/10—Devices using other cold materials; Devices using cold-storage bodies using liquefied gases, e.g. liquid air
Definitions
- the invention concerns cryosurgical apparatus, and relates in particular to a method of thawing a cryosurgical probe subsequent to carrying out a freezing process, in order that the probe may be withdrawn.
- the invention seeks to mitigate or obviate the above mentioned difficulties by providing a relatively f a sJ yet safe method of raising the temperature of the probe tip on completion of an operation.
- a method of thawing cryosurgical apparatus having an internal circulation system for fluid cryogen, which method comprises the steps of interrupting the supply of the cryogen to the apparatus, providing a supply of an inert gas, heating the gas to a required predetermined temperature, and circulating the heated gas through the cryogen circulation system of the apparatus to effect the required thawing.
- the method is particularly suited to liquid nitrogen cooled probes, such as the kind in which the cryogen is delivered to the probe tip via a delivery tube located along the probe axis and returned via an annular gap within the probe housing surrounding the delivery tube.
- the inert gas is nitrogen.
- the gas may be heated by feeding it to the apparatus via a heat exchanging arrangement.
- FIG. 1 is a schematic block diagram showing a cryosurgical probe arrangement for utilising the thawing method of the invention.
- the figure shows an arrangement containing four cryosurgical probes 10, 12, 14 and 16. Each probe is connected by a delivery line 20, 22, 24 and 26 to a supply vessel 28 of a fluid cryogen, such as liquid nitrogen.
- a fluid cryogen such as liquid nitrogen.
- the lines 20, 22, 24 and 26 are also in communic ⁇ ation with a further delivery line 30 as described in more detail hereinafter.
- the system provides a supply 40 of an inert gas, in the present example, nitrogen. Gas may be supplied through a delivery line 42 to a heat exchanging arrangement 44, and thus to the cryogen circulation systems of the probes 10, 12, 14 and 16 via the line 30 and the lines 20, 22, 24 and 26.
- an inert gas in the present example, nitrogen. Gas may be supplied through a delivery line 42 to a heat exchanging arrangement 44, and thus to the cryogen circulation systems of the probes 10, 12, 14 and 16 via the line 30 and the lines 20, 22, 24 and 26.
- Each of the probes 10, 12, 14 and 16 may be supplied with the cryogen from the supply vessel 28 in any convenient manner, such as via a delivery tube located along the respective probe longitudinal axis, as is well known in the art. Following the freezing of the probe tip, the cryogen is then removed, for example via an annular gap within a housing of the probe surrounding the delivery tube, to a suitable exhaust line on the probe . When the operation is complete and it is required to withdraw the probe, the supply of cryogen from the vessel 28 is shut off by means of a suitable valve arrangement. Gas is passed from the supply 40 through the line 42 to the heat exchanger 44. On passing through the heat exchanger, the gas is warmed to the required predetermined temperature.
- the gas supply is passed through the line 30 and then via suitable valve systems 48 to the supply line of the appropriate probe.
- the warmed nitrogen is thereby circulated through the probe body and tip whereby it provides localised heat within the probe tip.
- the gas may then be exhausted through the existing probe cryogen outlet lines-
- Any cryogen remaining within the probe circulation system is automatically purged by the incoming gas supply.
- control and monitoring of the apparatus can be achieved by the incorporation of any appropriate valves, gauges, regulators or other instrumentation as is well known to the person skilled in the art. Such systems are not therefore described in detail herein.
Landscapes
- Health & Medical Sciences (AREA)
- Surgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medical Informatics (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Otolaryngology (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Surgical Instruments (AREA)
- Defrosting Systems (AREA)
- Freezing, Cooling And Drying Of Foods (AREA)
- Thermotherapy And Cooling Therapy Devices (AREA)
Abstract
Description
Claims
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE69224842T DE69224842T2 (en) | 1991-11-05 | 1992-11-03 | METHOD FOR DEFROSTING A CRYOSURGICAL INSTRUMENT |
US08/232,281 US5632743A (en) | 1991-11-05 | 1992-11-03 | Method of thawing cryosurgical apparatus |
EP92922748A EP0611296B1 (en) | 1991-11-05 | 1992-11-03 | Method of thawing cryosurgical apparatus |
JP5508265A JPH07503626A (en) | 1991-11-05 | 1992-11-03 | How to thaw cryosurgical instruments |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB919123413A GB9123413D0 (en) | 1991-11-05 | 1991-11-05 | Method of thawing cryosurgical apparatus |
GB9123413.8 | 1991-11-05 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO1993008752A1 true WO1993008752A1 (en) | 1993-05-13 |
Family
ID=10704052
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/GB1992/002030 WO1993008752A1 (en) | 1991-11-05 | 1992-11-03 | Method of thawing cryosurgical apparatus |
Country Status (7)
Country | Link |
---|---|
US (1) | US5632743A (en) |
EP (1) | EP0611296B1 (en) |
JP (1) | JPH07503626A (en) |
AT (1) | ATE164054T1 (en) |
DE (1) | DE69224842T2 (en) |
GB (1) | GB9123413D0 (en) |
WO (1) | WO1993008752A1 (en) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0651308A1 (en) * | 1993-11-01 | 1995-05-03 | State of Israel Ministry of Defence Raphael Armament Development Authority | Controlled cryogenic contact system |
US5522870A (en) * | 1993-01-25 | 1996-06-04 | State Of Israel, Ministry Of Defense, Rafael-Armaments Development Authority | Fast changing heating-cooling device and method |
EP0925045A1 (en) * | 1996-07-23 | 1999-06-30 | Endocare, Inc. | Cryoprobe |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1998032383A1 (en) * | 1997-01-27 | 1998-07-30 | Cryomedical Sciences, Inc. | Hand-held cryosurgical probe system |
EP1014873A4 (en) * | 1997-09-22 | 2003-07-09 | Ethicon Inc | Cryosurgical system and method |
US20040243118A1 (en) * | 2001-06-01 | 2004-12-02 | Ayers Gregory M. | Device and method for positioning a catheter tip for creating a cryogenic lesion |
US7195625B2 (en) * | 2002-12-11 | 2007-03-27 | Cryocor, Inc. | Catheter system for performing a single step cryoablation |
US20050283146A1 (en) * | 2004-06-17 | 2005-12-22 | Lentz David J | Thermally extended spiral cryotip for a cryoablation catheter |
US7846154B2 (en) * | 2004-12-06 | 2010-12-07 | Galil Medical Ltd. | Gas-heated gas-cooled cryoprobe utilizing electrical heating and a single gas source |
US20060178662A1 (en) * | 2005-02-04 | 2006-08-10 | Ripley Kenneth L | Warming gradient control for a cryoablation applicator |
US8480664B2 (en) * | 2009-01-15 | 2013-07-09 | Boston Scientific Scimed, Inc. | Controlling depth of cryoablation |
US20100241113A1 (en) * | 2009-03-20 | 2010-09-23 | Boston Scientific Scimed, Inc. | Protecting the phrenic nerve while ablating cardiac tissue |
US8080005B1 (en) * | 2010-06-10 | 2011-12-20 | Icecure Medical Ltd. | Closed loop cryosurgical pressure and flow regulated system |
US9044313B2 (en) | 2010-10-08 | 2015-06-02 | Kfx Medical Corporation | System and method for securing tissue to bone |
CN102935010A (en) * | 2012-11-21 | 2013-02-20 | 湖南爱芷生医疗科技有限公司 | Deep hypothermia therapy apparatus for rectal cancer |
US11633224B2 (en) | 2020-02-10 | 2023-04-25 | Icecure Medical Ltd. | Cryogen pump |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4377168A (en) * | 1981-02-27 | 1983-03-22 | Wallach Surgical Instruments, Inc. | Cryosurgical instrument |
WO1983003961A1 (en) * | 1982-05-17 | 1983-11-24 | Andrzej Kamil Drukier | Cryoprobes, especially for the cryosurgery of deeply lying lesions |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3613689A (en) * | 1970-01-13 | 1971-10-19 | Frigitronics Of Conn Inc | Cryosurgical apparatus |
USRE28657E (en) * | 1972-05-08 | 1975-12-23 | Cryosurgical apparatus | |
DE2251626A1 (en) * | 1972-10-20 | 1974-04-25 | Linde Ag | CRYOSURGICAL PROBE |
GB1513565A (en) * | 1975-04-22 | 1978-06-07 | Spembly Ltd | Cryosurgical instruments |
US4018227A (en) * | 1975-10-09 | 1977-04-19 | Cryomedics, Inc. | Cryosurgical instrument |
US4275734A (en) * | 1977-08-12 | 1981-06-30 | Valleylab, Inc. | Cryosurgical apparatus and method |
AU3963078A (en) * | 1977-09-25 | 1980-03-13 | Kurio Medikaru Kk | Apparatus for refrigeration treatment |
IT1159748B (en) * | 1978-06-23 | 1987-03-04 | Bracco Dario | CRIOTHERAPY APPARATUS |
US4206760A (en) * | 1978-06-30 | 1980-06-10 | Cryomedics, Inc. | Bearing coupling for enabling the tip of a cryosurgical instrument to be rotated independently of inlet and exhaust tubes |
DE2831199C3 (en) * | 1978-07-15 | 1981-01-08 | Erbe Elektromedizin Gmbh & Co Kg, 7400 Tuebingen | Cryosurgical device |
CA1129015A (en) * | 1980-06-11 | 1982-08-03 | Timofei S. Gudkin | Thermoelectric cryoprobe |
SU1217377A1 (en) * | 1984-06-04 | 1986-03-15 | Физико-технический институт низких температур АН УССР | Method of thawing out cryosurgical instrument |
US5108390A (en) * | 1988-11-14 | 1992-04-28 | Frigitronics, Inc. | Flexible cryoprobe |
GB8829525D0 (en) * | 1988-12-17 | 1989-02-01 | Spembly Medical Ltd | Cryosurgical apparatus |
US4946460A (en) * | 1989-04-26 | 1990-08-07 | Cryo Instruments, Inc. | Apparatus for cryosurgery |
-
1991
- 1991-11-05 GB GB919123413A patent/GB9123413D0/en active Pending
-
1992
- 1992-11-03 DE DE69224842T patent/DE69224842T2/en not_active Expired - Fee Related
- 1992-11-03 AT AT92922748T patent/ATE164054T1/en not_active IP Right Cessation
- 1992-11-03 WO PCT/GB1992/002030 patent/WO1993008752A1/en active IP Right Grant
- 1992-11-03 EP EP92922748A patent/EP0611296B1/en not_active Expired - Lifetime
- 1992-11-03 JP JP5508265A patent/JPH07503626A/en active Pending
- 1992-11-03 US US08/232,281 patent/US5632743A/en not_active Expired - Fee Related
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4377168A (en) * | 1981-02-27 | 1983-03-22 | Wallach Surgical Instruments, Inc. | Cryosurgical instrument |
WO1983003961A1 (en) * | 1982-05-17 | 1983-11-24 | Andrzej Kamil Drukier | Cryoprobes, especially for the cryosurgery of deeply lying lesions |
Non-Patent Citations (2)
Title |
---|
Derwent's abstract, No 84-86 863/14, week 8414, ABSTRACT OF SU 1 024 075, (ODESS MED INST), 1983-06-23 * |
Derwent's abstract, No 86-296 896/45, week 8645, ABSTRACT OF SU 1 217 377, (AS UKR LOW TEMP PHYSICS), 1986-03-15 * |
Cited By (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5522870A (en) * | 1993-01-25 | 1996-06-04 | State Of Israel, Ministry Of Defense, Rafael-Armaments Development Authority | Fast changing heating-cooling device and method |
US5702435A (en) * | 1993-01-25 | 1997-12-30 | State Of Israel Ministry Of Defense, Rafael-Armaments | Fast changing heating-cooling device and method |
US5891188A (en) * | 1993-01-25 | 1999-04-06 | State Of Israel, Ministry Of Defense, Rafael-Armaments Development Authority | Fast changing heating-cooling device and method |
EP0651308A1 (en) * | 1993-11-01 | 1995-05-03 | State of Israel Ministry of Defence Raphael Armament Development Authority | Controlled cryogenic contact system |
US5540062A (en) * | 1993-11-01 | 1996-07-30 | State Of Israel, Ministry Of Defence, Rafael Armaments Development Authority | Controlled cryogenic contact system |
US5577387A (en) * | 1993-11-01 | 1996-11-26 | State Of Israel, Ministry Of Defence, Rafael-Armaments Development Authority | Controlled cryogenic contact system |
EP0925045A1 (en) * | 1996-07-23 | 1999-06-30 | Endocare, Inc. | Cryoprobe |
EP0925045A4 (en) * | 1996-07-23 | 1999-09-15 | Endocare Inc | Cryoprobe |
Also Published As
Publication number | Publication date |
---|---|
EP0611296A1 (en) | 1994-08-24 |
ATE164054T1 (en) | 1998-04-15 |
JPH07503626A (en) | 1995-04-20 |
GB9123413D0 (en) | 1991-12-18 |
DE69224842T2 (en) | 1998-09-17 |
EP0611296B1 (en) | 1998-03-18 |
US5632743A (en) | 1997-05-27 |
DE69224842D1 (en) | 1998-04-23 |
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