WO1992010139A1 - Element de raclage de tissus a usage medical - Google Patents
Element de raclage de tissus a usage medical Download PDFInfo
- Publication number
- WO1992010139A1 WO1992010139A1 PCT/US1990/007506 US9007506W WO9210139A1 WO 1992010139 A1 WO1992010139 A1 WO 1992010139A1 US 9007506 W US9007506 W US 9007506W WO 9210139 A1 WO9210139 A1 WO 9210139A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- tissue
- tip
- shank
- longitudinal axis
- source
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/007—Methods or devices for eye surgery
- A61F9/00736—Instruments for removal of intra-ocular material or intra-ocular injection, e.g. cataract instruments
- A61F9/00745—Instruments for removal of intra-ocular material or intra-ocular injection, e.g. cataract instruments using mechanical vibrations, e.g. ultrasonic
Definitions
- the present invention relates to a tissue scraper element for medical use, and more particularly to such an element usable in extracting undesired body tissue, e.g. a cataracted natural eye lens, by mechanical vibratory contact to disin ⁇ tegrate the tissue and by accompanying flushing fluid flow removal of the disintegrated tissue from the tissue site, the element including a shank, mountable on a hand held instrument for longitudinal back and forth vibratory movement, and having a crosswise extending tip terminating in a laterally outwardly directed scraper edge, a flow channel in the tip communicating a flow passage in the shank with a mouth adjacent the scraper edge to accommodate such flushing fluid flow.
- tissue scraper element for medical use, and more particularly to such an element usable in extracting undesired body tissue, e.g. a cataracted natural eye lens, by mechanical vibratory contact to disin ⁇ tegrate the tissue and by accompanying flushing fluid flow removal of the disintegrated tissue from the tissue site
- the element including a shank
- U.S. Pat. 3,589,363 to Banko and Kel an discloses a hand held instrument and method for breaking apart and removing by flushing fluid flow undesired material such as tissue from a body site.
- the instrument contains vibratory movement means connected to a longitudinal shank having an axial bore leading to a mouth at its projecting straight tip, and a conduit leading to an opening at the shank exterior, such that axial vibratory movement of the tip, when pressed axially against the tissue, breaks up the tissue by jack-hammer-like action, for removal by flow of fluid from a source to the site via one of the mouth and opening and its return with broken up tissue via the other of the mouth and opening to a suction source.
- This patent teaching has been used for break up and removal of cataracted eye lens tissue per known surgical procedures. Such procedures are effected through a corneal incision kept as small as possible to minimize patient trauma. In this regard, it is desirable to remove all tissue debris from the posterior capsule.
- the procedure is burdened by awkwardness in the positioning of the instrument in the surgeon's hand under the extant vibratory conditions, especially when attempting to break up portions of the cata- racted lens tissue in remote portions of the posterior capsule in relation to the fixed position of the necessarily small corneal incision.
- the instrument of this patent may be provided with a radially extending, sharp pointed projection, this is only used to tear the anterior wall of the capsule covering the lens by back and forth tearing action to obtain access to the lens prior to initiation of the tissue breaking apart procedure.
- This projection would be of no value in breaking apart the main mass of the lens tissue within its capsule, especially consid ⁇ ering that the projection has a pointed end and is positioned with that end remote from the tip mouth through which the flushing fluid flows.
- the back and forth jack-hammer-like action of the straight tip of the instrument of this patent which is used for the actual breaking up of the lens tissue, operates by way of axial or longitudinal direction percussion impulse exerted perpendicularly against the tissue surface as anvil, inherently resulting in a coarse shattering of the tissue.
- the surgeon must take pains to manipulate th tip through many diverse angular positions, while the shank extends through the relatively small incision, to be able to apply the leading transverse face of the longitudinal straight tip in "head-on" relation with the lens tissue, as the very nature of the percussion impulse action is such that the axially vibrating tip makes head-on face-to-face contact with the tissue surface.
- care must be taken to avoid unduly pressing the tip against the tissue surface of the posterior wall of the capsule for fear of puncturing or otherwise damaging unnecessarily that wall which is intended to remain intact.
- tissue scraper element for medical use in extracting undesired body tissue, e.g. the natural eye lens, by mechanical vibrator contact to disintegrate the tissue arid by accompanying flushin fluid flow removal of the disintegrated tissue from the tissue site, with the element in use being mounted on a hand held instrument for back and forth vibratory movement in a longitud inal direction but which has an offset tip provided with a scraper edge for contacting the tissue in a direction generall crosswise of the vibratory movement direction, resulting in efficient and uniform extraction of the undesired tissue at minimum patient risk and maximum comfort to the surgeon's hand and fingers.
- a tissue scraper element is advantageously provided for medical use in extracting undesired body tissue by mechanical vibratory contact to disintegrate the tissue and by accompanying flushing fluid flow removal of the disintegrated tissue from the tissue site.
- the tissue scraper element includes a shank extending along a longitudinal axis and having a base end portion adapted to be mounted on a hand held instrument for back and forth vibratory movement of the shank in the direction of its longitudinal axis at a selective amplitude and frequency, and a free end portion terminating in a sidewise offset or bent tip extending along a lateral, preferably radial, axis crosswise of said longitudinal axis.
- the shank has an exterior surface and an internal fluid flow passage, and the tip terminates in a laterally, preferably radially, outwardly directed scraper edge spaced laterally, preferably radially, outwardly beyond the shank exterior surface and arranged for such vibratory movement " in the direction of said longitudinal axis and has an internal fluid flow channel communicating with the shank passage and outwardly terminating in a mouth adjacent the scraper edge.
- the tissue upon contacting the scraper edge against the undesired tissue in a direction crosswise of said longitudinal axis while subjecting the shank and tip to such vibratory movement in the direction of said longitudinal axis and to such accompanying flushing fluid flow via the tip mouth, the tissue will be effectively locally disintegrated and removed from the tissue site.
- the shank and tip are integrally intercon ⁇ nected by an elbow like transition portion therebetween, and are both of tubular configuration.
- the scraper edge favorably lies in a laterally, preferably radially, offset plane generally parallel to a longitudinal plane passing through said longitudinal axis, and is of generally ring shaped perimetric configuration in concentric relation to the tip lateral, preferably radial, axis and arranged to define the mouth of the tip channel. More specifi cally, the scraper edge may define a generally flat edge, or line edge, end surface in that offset plane.
- a combination comprising the tissue scraper element mounted on a hand held instrument via the base end portion of the element shank.
- the instrument contains a vibratory movement means operatively connected to the shank fo imparting back and forth vibratory movement to the shank in th direction of its longitudinal axis at a selective amplitude an frequency, and the instrument is provided with an opening adjacent the shaft exterior surface, and a source of flushing fluid and a source of fluid suction, one of said sources being flow connected to the opening and the other of said sources being flow connected to the tip mouth.
- the instrument and tissue scraper element are sized for use in treating an eye, and the shaft and tip are sized for insertion through a corneal incision into the eye fo extracting portions of the tissue of the natural eye lens.
- a method of using the tissue scraper element for extracting undesired tissue from a body tissue site.
- the method comprises contacting the scraper edge against the undesired tissue, such as that of a cataracted natural eye lens, in a direction crosswise of said longitudinal axis while subjecting the shank and tip to back and forth vibratory movement of the shank and tip in the direction of said longi- tudinal axis sufficiently to disintegrate the tissue by mechanical vibratory contact of the scraper edge therewith, an while also subjecting the tissue site to accompanying flushing fluid flow via the tip mouth sufficiently to flush and remove the disintegrated tissue from the tissue site by such flow.
- the undesired tissue such as that of a cataracted natural eye lens
- the subjecting of the tissue site to accom ⁇ panying flushing fluid flow includes supplying such fluid via the source of flushing fluid through one of said opening and said tip mouth sufficiently to flush the disintegrated tissue, and supplying such suction via the source of fluid suction through the other of said opening and said tip mouth suffi ⁇ ciently to remove the disintegrated tissue from the site.
- the subjecting of the tissue site to said flushing fluid flow includes supplying such fluid via the source of flushing fluid through said opening sufficiently to flush the disintegrated tissue, and supplying such suction via the source of fluid suction through said tip mouth sufficiently to remove the disintegrated tissue from the site.
- Fig. 1 is a schematic partial sectional view of a conven ⁇ tional hand held vibratory movement imparting and flushing fluid flow supplying instrument in which the tissue scraper element of the invention is mounted;
- Fig. 2a is an enlarged schematic longitudinal sectional view of the round profile tissue scraper element of Fig. 1, showing details and relationships of pertinent parts;
- Fig. 2b is a top view of said element shown in Fig. 2a;
- Fig. 2c is a front elevational view of said element shown in Fig. 2a;
- Fig. 3a is an enlarged schematic longitudinal sectional view similar to the embodiment of Figs. 2a, 2b and 2c, but of an oval profile tissue scraper element.
- Fig. 3b is a top view of said element shown in Fig. 3a;
- Fig. 3c is a transverse sectional view taken along line 3c-3c of Fig. 3b.
- Fig. 4a is a view similar to Fig. 2a but of a further alternate form of the tissue scraper element in which the scraper edge is a convexly arranged pointed or linear edge;
- Fig. 4b is a view similar to Fig. 4a of a still further alternate form of said element in which the scraper edge is a concavely arranged pointed or linear edge;
- Fig. 5 is a schematic view of an eye showing insertion of the instrument of Fig. 1 through a corneal incision thereinto for disintegration and removal of tissue of the natural lens by the tissue scraper element of the invention
- Fig. 6 is a schematic partial front elevational view of the eye showing the natural lens of the eye partially disin ⁇ tegrated and in doughnut form, indicating in solid line, and alternatively in phantom, two positions of the tissue scraper element of the invention used to disintegrate and remove tissue from different remote regions of the cataracted lens by mere rotation of the tool in the surgeon's hand.
- a combination assembly 1 is shown of a known hand held vibratory motion imparting and flushing fluid supplying and removing instrument 2, e.g. as disclosed in said U.S. Pat. 3,589,363 to Banko and Kelman, having the tissue scraper element 3 of the invention, e.g. of about 1 mm external diameter, mounted therein, the parts being sized for use in treating an eye.
- instrument 2 e.g. as disclosed in said U.S. Pat. 3,589,363 to Banko and Kelman
- the tissue scraper element 3 of the invention e.g. of about 1 mm external diameter, mounted therein, the parts being sized for use in treating an eye.
- the disclosure of said U.S. Pat. 3,589,363 is hereby incorporated herein in its entirety.
- Instrument 2 is formed of a longitudinal housing 4 containing a conventional oscillator or vibrator 5, energized by power lines 6 and 7, and cooled by cooling fluid entering sealed rear chamber 8 via inlet hose 9 and leaving rear chamber 8 via outlet hose 10, lines 6 and 7 and hoses 9 and 10 being connected to appropriate sources, e.g. of electrical current and tap water, respectively, through service conduit 11.
- a conventional oscillator or vibrator 5 energized by power lines 6 and 7, and cooled by cooling fluid entering sealed rear chamber 8 via inlet hose 9 and leaving rear chamber 8 via outlet hose 10, lines 6 and 7 and hoses 9 and 10 being connected to appropriate sources, e.g. of electrical current and tap water, respectively, through service conduit 11.
- Vibrator 5 is provided with a forward extension 12 mounted in housing 4 by a pair of axially spaced sealing rings 13,14 to define an annular sealed middle chamber 15 between housing 4 and vibrator extension 12, so as to flow communicate external suction line 16, which is connectable to a fluid suction source (not shown), with vibrator axial bore 17 leading from vibrator extension 12 completely through vibrator front end 18 on which tissue scraper element 3 of the invention is operatively mounted for back and forth longitudinal vibratory movement at a selective amplitude and frequency, e.g. about 0.003 inch amplitude and about 1,000 to 100,000 cycles per second frequen ⁇ cy, and for fluid flow through the interior of element 3.
- a selective amplitude and frequency e.g. about 0.003 inch amplitude and about 1,000 to 100,000 cycles per second frequen ⁇ cy
- connector 19 releasably operatively connects the base end 20 of the longitudinal shank 21 of element 3 to vibrator front end 18, such that the front free end 22 of shank 21 protrudes a selective significant distance forwardly of housing 4 and extends along its longitudinal axis A which coincides with that of instrument vibrator 5.
- free end 22 terminates in a sidewise offset or bent tip 23 which extends along a lateral, e.g. radial, axis B, crosswise of longitudinal axis A, tip 23 terminating in a laterally, e.g. radially, outwardly directed scraper edge 24.
- Flushing fluid line 25 which is connectable to a fluid supply source (not shown), e.g. saline solution, in convention ⁇ al manner, flow communicates via housing front chamber 26 with housing front annular opening 27 to supply flushing fluid to the adjacent exterior surface 28 of shank 21, preferably after having first passed from opening 27 through an optional forwardly mounted resilient plastic sleeve 29 and out through the corresponding sleeve annular opening 30, to the region of the body tissue under treatment, sleeve 29 serving to protect the eye from undesired rubbing contact with the adjacent rigid surfaces of instrument 2 during its vibratory movement.
- a fluid supply source e.g. saline solution
- shank 21 is provided with a longitudinal internal fluid flow passage 31, which communicates with axial bore 17 when element 3 is connected by connector 19 onto vibrator fron end 18, and tip 23 is provided with an interior fluid flow channel 32 which communicates with shank passage 31 in the elbow like transition portion integrally interconnecting shank 21 and tip 23 (see Fig. 2a), channel 32 outwardly terminating in a mouth 33 adjacent scraper edge 24.
- shank 21 and tip 23 are conveniently both provided of tubular configuration.
- scraper edge 24 is spaced laterally outwardly beyond shank exterior surface 28 and is arranged for such back and forth vibratory movement in the longitudinal direction of axis A, whereupon when scraper edge 24 is used to contact and disintegrate the undesired tissue, the remainder of element 3, i.e. the adjacent shank exterior surface 28, will not make contact with the tissue, thereby avoiding undesired disturbance of the delicate manipulations necessary for achieving the gentle, yet efficient, scraping disintegration action sought.
- scraper edge 24 lies in a laterally, e.g. radially, offset plane P which is generally parallel to a longitudinal plane L passing through longitudinal axis A of shank 21 and instrument 2
- scraper edge 24 is of generally ring shaped perimetric config ⁇ uration in concentric relation to lateral, e.g. radial, axis B, being arranged to define mouth 33 of tip channel 32.
- tip 23, and in turn channel 32, mouth 33 and scraper edge 24, are of corresponding circular shape, as especially shown in Figs. 2b and 2c
- Figs. 3a, 3b and 3c wherein like parts are assigned like reference numbers but with prime ( ' ) designa- tions, that these parts may instead be of corresponding oval shape, as especially shown in Figs. 3b and 3c.
- these parts may also be of other appropriate shape as desired, so long as the scraper edge in cooperation with the tip mouth function properly for the underlying purposes of element 3.
- scraper edge 24 defines a generally flat edge end surface in offset plane P, i.e. a square cornered flat edge cross sectional shape, in the embodiment of Figs. 2a, 2b and 2c, it will be seen that alternative shapes may instead be used such as line edge end surface shapes, i.e. pointed edge cross sectional shapes, as shown per scraper linear edge 24a in Fig.4a and scraper linear edge 24b in Fig. 4b.
- the eyeball 50 includes the cornea 51, the iris 52 which forms the adjustable central pupil or opening 52a and which separates the anterior chamber 53 from the posterior chamber 54, and the natural eye lens 55, located by the zonules or suspensory ligament and fibers 56, attached to its periphery, in posterior chamber 54.
- Eye lens 55 is contained in lens capsule 57 which includes anterior wall 58, posterior wall 59 and cul-de-sac or peripheral groove 60.
- a corneal incision 61 is typically made of minimum length, e.g.
- incision 61 is desirably kept as short in length as possible so as to minimize trauma to the patient, and thus its length is normally just sufficient for effecting the contemplated tissue removal procedure,, e.g. for extracapsular removal of a cataracted natural eye lens, and, if called for, for receiving therethrough an intraocular lens to be implanted in the eye thereafter.
- tissue removal procedure e.g. for extracapsular removal of a cataracted natural eye lens
- intraocular lens intraocular lens
- FIG. 6 wherein the solid line and phantom illustrations show how tip 23 may be more readily manipulated to contact tissue on different portions of the lens for more efficient disintegration and removal of the undesired lens tissue with minimal movement of the tip required by the surgeon.
- incision 61 in eyeball 50 in relation to remote areas of the lens, and the fact that such remote areas can only be reached through pupil 52a as access opening, such rotational (about its longitudinal axis) movement of the tip permits the surgical procedure of cataract removal to be carried out with much greater speed.
- the surgeon can quickly move from one to another spaced region of the lens.
- the surgeon may not only move shank 21 longitudinally and angularly to place tip 23 at any areal point in capsule 57 (within the areal bounds of the capsule plane of Fig. 6) and at any crosswise width point therein (within the crosswise width bounds of the section plane of Fig. 5 or any other section plane through capsule 57), but also rapidly and easily twist or rock shank 21 about its axis at that, or any other, areal and width point to place scraper edge 24 at any localized spatial angular attitude among an essentially infinite number of attitudes (e.g.
- tip 23 which is bent transversely relative to shank 21, moves in a back and forth vibratory path generally parallel to longitudinal axis A, enabling scraper edge 24 to be urged generally transversely, e.g. perpendicularly, to axis A and to the tissue surface, so as to contact safely and scrape away tissue by a milling or frictional type horizontal scraping action in a gradual and uniformly controlled manner for more precise, even and smooth one-step cleansing and removal of undesired tissue as finer individual particles, more readily flushed away by the fluid flow, and without fear of puncturing or otherwise damaging tissue intended to remain intact, such as posterior wall 59 and peripheral groove 60 (cf. Figs. 5 and 6).
- the flushing fluid is preferably aseptic saline solution or the like, whereas tap water may be used for cooling vibrator 5 since rear chamber 8 of housing 4 is safely sealed off from the remainder of the unit.
- shank 21 and tip 23, and optional sleeve 29, must be sized for convenient insertion through a given minimum size corneal incision.
- sleeve 29 is preferred to soften the rubbing action of that portion of vibrating instrument 2 in contact with the corneal incision or any other adjacent portion of the eye, and thus minimize patient discomfort or trauma due to heat genera ⁇ tion or otherwise.
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- Health & Medical Sciences (AREA)
- Ophthalmology & Optometry (AREA)
- Heart & Thoracic Surgery (AREA)
- Surgery (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Vascular Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
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Abstract
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/US1990/007506 WO1992010139A1 (fr) | 1990-12-14 | 1990-12-14 | Element de raclage de tissus a usage medical |
CA002098403A CA2098403A1 (fr) | 1990-12-14 | 1990-12-14 | Dispositif de raclage tissulaire pour usage medical |
EP19910902473 EP0566565A4 (en) | 1990-12-14 | 1990-12-14 | Tissue scraper element for medical use |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/US1990/007506 WO1992010139A1 (fr) | 1990-12-14 | 1990-12-14 | Element de raclage de tissus a usage medical |
CA002098403A CA2098403A1 (fr) | 1990-12-14 | 1990-12-14 | Dispositif de raclage tissulaire pour usage medical |
Publications (1)
Publication Number | Publication Date |
---|---|
WO1992010139A1 true WO1992010139A1 (fr) | 1992-06-25 |
Family
ID=25676278
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US1990/007506 WO1992010139A1 (fr) | 1990-12-14 | 1990-12-14 | Element de raclage de tissus a usage medical |
Country Status (1)
Country | Link |
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WO (1) | WO1992010139A1 (fr) |
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5346469A (en) * | 1992-10-07 | 1994-09-13 | Sumitomo Bakelite Company Limited | Handpiece for surgical operation |
US5417654A (en) * | 1994-02-02 | 1995-05-23 | Alcon Laboratories, Inc. | Elongated curved cavitation-generating tip for disintegrating tissue |
US9433725B2 (en) | 2011-12-23 | 2016-09-06 | Alcon Research, Ltd. | Combined coaxial and bimanual irrigation/aspiration apparatus |
US9839738B2 (en) | 2013-06-06 | 2017-12-12 | Novartis Ag | Transformer irrigation/aspiration device |
CN108671285A (zh) * | 2018-06-07 | 2018-10-19 | 丁艳 | 一种乳腺科护理刮吸器 |
CN111902109A (zh) * | 2018-04-04 | 2020-11-06 | 韦菲斯股份有限公司 | 外科仪器、特别是超声乳化机头 |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3589363A (en) * | 1967-07-25 | 1971-06-29 | Cavitron Corp | Material removal apparatus and method employing high frequency vibrations |
US4301802A (en) * | 1980-03-17 | 1981-11-24 | Stanley Poler | Cauterizing tool for ophthalmological surgery |
US4570632A (en) * | 1984-03-16 | 1986-02-18 | Woods Randall L | Cystotome for eye surgery and method of opening lens capsule |
US4869716A (en) * | 1988-10-24 | 1989-09-26 | Smirmaul Heinz J | Surgical instrument and method for cutting the lens of an eye |
US4909249A (en) * | 1987-11-05 | 1990-03-20 | The Cooper Companies, Inc. | Surgical cutting instrument |
-
1990
- 1990-12-14 WO PCT/US1990/007506 patent/WO1992010139A1/fr not_active Application Discontinuation
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3589363A (en) * | 1967-07-25 | 1971-06-29 | Cavitron Corp | Material removal apparatus and method employing high frequency vibrations |
US4301802A (en) * | 1980-03-17 | 1981-11-24 | Stanley Poler | Cauterizing tool for ophthalmological surgery |
US4570632A (en) * | 1984-03-16 | 1986-02-18 | Woods Randall L | Cystotome for eye surgery and method of opening lens capsule |
US4909249A (en) * | 1987-11-05 | 1990-03-20 | The Cooper Companies, Inc. | Surgical cutting instrument |
US4869716A (en) * | 1988-10-24 | 1989-09-26 | Smirmaul Heinz J | Surgical instrument and method for cutting the lens of an eye |
Non-Patent Citations (1)
Title |
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See also references of EP0566565A4 * |
Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5346469A (en) * | 1992-10-07 | 1994-09-13 | Sumitomo Bakelite Company Limited | Handpiece for surgical operation |
US5417654A (en) * | 1994-02-02 | 1995-05-23 | Alcon Laboratories, Inc. | Elongated curved cavitation-generating tip for disintegrating tissue |
WO1995020928A1 (fr) * | 1994-02-02 | 1995-08-10 | Alcon Laboratories, Inc. | Extremite allongee et courbe generant une cavitation, pour desintegrer des tissus |
US9433725B2 (en) | 2011-12-23 | 2016-09-06 | Alcon Research, Ltd. | Combined coaxial and bimanual irrigation/aspiration apparatus |
US9839738B2 (en) | 2013-06-06 | 2017-12-12 | Novartis Ag | Transformer irrigation/aspiration device |
CN111902109A (zh) * | 2018-04-04 | 2020-11-06 | 韦菲斯股份有限公司 | 外科仪器、特别是超声乳化机头 |
CN108671285A (zh) * | 2018-06-07 | 2018-10-19 | 丁艳 | 一种乳腺科护理刮吸器 |
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