WO1990006116A3 - Agents for treating chronic inflammatory diseases of the intestines - Google Patents

Agents for treating chronic inflammatory diseases of the intestines Download PDF

Info

Publication number
WO1990006116A3
WO1990006116A3 PCT/EP1989/001426 EP8901426W WO9006116A3 WO 1990006116 A3 WO1990006116 A3 WO 1990006116A3 EP 8901426 W EP8901426 W EP 8901426W WO 9006116 A3 WO9006116 A3 WO 9006116A3
Authority
WO
WIPO (PCT)
Prior art keywords
intestines
inflammatory diseases
chronic inflammatory
agents
treating chronic
Prior art date
Application number
PCT/EP1989/001426
Other languages
German (de)
French (fr)
Other versions
WO1990006116A2 (en
Inventor
Ekkehard Scheiffele
Gerhard Gerber
Werner Siems
Andreas Werner
Original Assignee
Henning Berlin Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Henning Berlin Gmbh filed Critical Henning Berlin Gmbh
Priority to DE8989912949T priority Critical patent/DE58903550D1/en
Priority to AT89912949T priority patent/ATE85522T1/en
Publication of WO1990006116A2 publication Critical patent/WO1990006116A2/en
Publication of WO1990006116A3 publication Critical patent/WO1990006116A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0031—Rectum, anus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Abstract

Chronic inflammatory diseases of the intestines can be treated by enteral administration of pharmacologically effective doses of oxypurinol and/or its alkali, alkaline earth or ammonium salts.
PCT/EP1989/001426 1988-11-25 1989-11-24 Agents for treating chronic inflammatory diseases of the intestines WO1990006116A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
DE8989912949T DE58903550D1 (en) 1988-11-25 1989-11-24 AGENTS FOR TREATING CHRONICALLY INFLAMMABLE COLON DISEASES.
AT89912949T ATE85522T1 (en) 1988-11-25 1989-11-24 MEANS OF TREATMENT OF CHRONIC INFLAMMATORY INTESTINAL DISEASES.

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3839839A DE3839839A1 (en) 1988-11-25 1988-11-25 AGENTS FOR TREATING CHRONICALLY INFLAMMABLE COLON DISEASES
DEP3839839.7 1988-11-25

Publications (2)

Publication Number Publication Date
WO1990006116A2 WO1990006116A2 (en) 1990-06-14
WO1990006116A3 true WO1990006116A3 (en) 1990-08-23

Family

ID=6367891

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP1989/001426 WO1990006116A2 (en) 1988-11-25 1989-11-24 Agents for treating chronic inflammatory diseases of the intestines

Country Status (5)

Country Link
EP (1) EP0445156B1 (en)
JP (1) JP2686566B2 (en)
DE (2) DE3839839A1 (en)
ES (1) ES2054097T3 (en)
WO (1) WO1990006116A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE0102315D0 (en) * 2001-06-28 2001-06-28 Astrazeneca Ab Compounds
SE0203825D0 (en) * 2002-12-20 2002-12-20 Astrazeneca Ab Novel fused heterocycles and uses thereof
WO2006083687A1 (en) * 2005-01-28 2006-08-10 Cardiome Pharma Corp. Crystal salt of xanthine oxidase inhibitors

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB975850A (en) * 1955-08-10 1964-11-18 Wellcome Found Xanthine oxidase inhibitors
AT352686B (en) * 1976-03-23 1979-10-10 Spiegl Paul Dr METHOD OF MANUFACTURING MICROCAPSULES
EP0062000A2 (en) * 1981-03-18 1982-10-06 Stafford-Miller Continental Use of 4-aminosalicylic acid as an anti-inflammatory agent
EP0261439A2 (en) * 1986-08-28 1988-03-30 Mect Corporation Medicament for curing arteriosclerosis, comprising pyrimido (2,1-b) benzothiazole derivative

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3764676D1 (en) * 1986-03-13 1990-10-11 Wellcome Found CELL PROTECTION.

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB975850A (en) * 1955-08-10 1964-11-18 Wellcome Found Xanthine oxidase inhibitors
AT352686B (en) * 1976-03-23 1979-10-10 Spiegl Paul Dr METHOD OF MANUFACTURING MICROCAPSULES
EP0062000A2 (en) * 1981-03-18 1982-10-06 Stafford-Miller Continental Use of 4-aminosalicylic acid as an anti-inflammatory agent
EP0261439A2 (en) * 1986-08-28 1988-03-30 Mect Corporation Medicament for curing arteriosclerosis, comprising pyrimido (2,1-b) benzothiazole derivative

Also Published As

Publication number Publication date
DE3839839A1 (en) 1990-05-31
EP0445156B1 (en) 1993-02-10
JPH04502005A (en) 1992-04-09
ES2054097T3 (en) 1994-08-01
EP0445156A1 (en) 1991-09-11
DE58903550D1 (en) 1993-03-25
WO1990006116A2 (en) 1990-06-14
DE3839839C2 (en) 1991-12-19
JP2686566B2 (en) 1997-12-08

Similar Documents

Publication Publication Date Title
EP0379806A3 (en) Pyrimidines and their pharmaceutical acceptable salts, and their use as medicines
TW234691B (en)
AU6837690A (en) Blocking agents of edrf effect or formation for the treatment of shock
CA2125662A1 (en) Transdermally administered system containing acetylsalicylic acid for thrombosis therapy and cancer prophylaxis
NO880182D0 (en) PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE 1, 2-DIHYDRO-3H-INDAZOL-3H-INDAZOL-3-ON DERIVATIVES.
IL90551A (en) Stable, injectable, aqueous pharmaceutical compositions for the treatment of cardiac conditions
NO883122D0 (en) PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE ARYLAMIDE DERIVATIVES.
NO884176L (en) PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE AMIDINO DERIVATIVES.
WO1990006116A3 (en) Agents for treating chronic inflammatory diseases of the intestines
GR3025518T3 (en) Use of the N-n-butyl derivative of desoxynojirimycin in the manufacture of a medicament inhibiting HIV-Virus
AU8447991A (en) Antineoplastic effect potentiator and antineoplastic agent
DE69032000D1 (en) Treatment of cardiac dysfunction with 15-keto-prostaglandin derivatives
FI901876A0 (en) OFULLSTAENDIGA HEPADNAVIRUS, VACCIN PRODUCERANDE CELLINJER SAMT THERAPY AV LEVERSJUKDOMAR.
HRP970171A2 (en) Use of bradykinin antagonists for the preparation of medicaments to treat chronic fibrogenetic liver disease and acute liver disease
WO1986006960A3 (en) Use of nicorandil or pinacidil for the treatment of peripheral vascular disease
NO890607L (en) PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE PYRIDINE DERIVATIVES.
IE840977L (en) Pharmaceutical preparations
JPS55113721A (en) Immunity regulator
EP0357072A3 (en) Use of zofenopril for the preparation of drugs against rheumatoid arthritis
EP0260790A3 (en) Use of pinacidil in the treatment of incontinence
EP0400312A3 (en) Method and composition for treating protozoal infections with a novel antibacterial agent
ES2169117T3 (en) USE OF DERIVATIVES OF 2-AMINOPURIN IN THE TREATMENT AND PROFILAXIS OF INFECTION BY VIRUS 7 OF THE HUMAN HERPES.
EP0419354A3 (en) Use of a complex of inosine with a n,n-dialkylamino-alkanol or one of its salts with a pharmacologically acceptable acid for the treatment of certain helmintic infections
NO891045D0 (en) PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE QUINOLIN-2,5-DION DERIVATIVES.
AU4246189A (en) Medicament for the treatment of diseases caused by retroviruses

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): JP US

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): AT BE CH DE ES FR GB IT LU NL SE

AK Designated states

Kind code of ref document: A3

Designated state(s): JP US

AL Designated countries for regional patents

Kind code of ref document: A3

Designated state(s): AT BE CH DE ES FR GB IT LU NL SE

WWE Wipo information: entry into national phase

Ref document number: 1989912949

Country of ref document: EP

WWP Wipo information: published in national office

Ref document number: 1989912949

Country of ref document: EP

WWG Wipo information: grant in national office

Ref document number: 1989912949

Country of ref document: EP