WO1989000830A1 - Blood collecting tube - Google Patents

Blood collecting tube Download PDF

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Publication number
WO1989000830A1
WO1989000830A1 PCT/JP1988/000746 JP8800746W WO8900830A1 WO 1989000830 A1 WO1989000830 A1 WO 1989000830A1 JP 8800746 W JP8800746 W JP 8800746W WO 8900830 A1 WO8900830 A1 WO 8900830A1
Authority
WO
WIPO (PCT)
Prior art keywords
tube
blood collection
bottomed
blood
collection tube
Prior art date
Application number
PCT/JP1988/000746
Other languages
French (fr)
Japanese (ja)
Inventor
Masaaki Kasai
Kenji Ishikawa
Sakae Yamazaki
Original Assignee
Terumo Kabushiki Kaisha
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Terumo Kabushiki Kaisha filed Critical Terumo Kabushiki Kaisha
Priority to AU20825/88A priority Critical patent/AU2082588A/en
Publication of WO1989000830A1 publication Critical patent/WO1989000830A1/en

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Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
    • B01L3/5082Test tubes per se
    • B01L3/50825Closing or opening means, corks, bungs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150015Source of blood
    • A61B5/15003Source of blood for venous or arterial blood
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150351Caps, stoppers or lids for sealing or closing a blood collection vessel or container, e.g. a test-tube or syringe barrel
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150374Details of piercing elements or protective means for preventing accidental injuries by such piercing elements
    • A61B5/150381Design of piercing elements
    • A61B5/150389Hollow piercing elements, e.g. canulas, needles, for piercing the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150374Details of piercing elements or protective means for preventing accidental injuries by such piercing elements
    • A61B5/150381Design of piercing elements
    • A61B5/150473Double-ended needles, e.g. used with pre-evacuated sampling tubes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150374Details of piercing elements or protective means for preventing accidental injuries by such piercing elements
    • A61B5/150534Design of protective means for piercing elements for preventing accidental needle sticks, e.g. shields, caps, protectors, axially extensible sleeves, pivotable protective sleeves
    • A61B5/150572Pierceable protectors, e.g. shields, caps, sleeves or films, e.g. for hygienic purposes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150374Details of piercing elements or protective means for preventing accidental injuries by such piercing elements
    • A61B5/150534Design of protective means for piercing elements for preventing accidental needle sticks, e.g. shields, caps, protectors, axially extensible sleeves, pivotable protective sleeves
    • A61B5/150694Procedure for removing protection means at the time of piercing
    • A61B5/150717Procedure for removing protection means at the time of piercing manually removed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150732Needle holders, for instance for holding the needle by the hub, used for example with double-ended needle and pre-evacuated tube
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/153Devices specially adapted for taking samples of venous or arterial blood, e.g. with syringes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/153Devices specially adapted for taking samples of venous or arterial blood, e.g. with syringes
    • A61B5/154Devices using pre-evacuated means

Definitions

  • the present invention relates to a blood collection tube. More specifically, the present invention relates to a blood collection tube to which a film-like sealing member having an open bottomed tube is adhered.
  • the blood collection tube used for example, a vacuum blood collection tube, is composed of a bottomed tube made of glass or plastic, a rubber stopper, and a force.
  • the serum can be collected using the automatic serum collection device without removing the rubber stopper.
  • Decompression blood collection tubes are preferred.
  • Such a blood collection tube is a film-like seal that allows the collection needle of an automatic serum collection device to directly penetrate the opening of the bottomed tube instead of the rubber stopper.
  • There is a reduced-pressure blood collection tube that is attached to a member to prevent external contamination.
  • a blood test must be performed without using an automatic serum collection device.
  • the serum may be collected by peeling the rubber-shaped sealing member.
  • the blood In a low-pressure blood collection tube that does not require a rubber stopper as described above, the blood is called a conventional pi wing and decantation.
  • it is necessary to peel off the film-like sealing member that seals the opening of the bottomed pipe.
  • the sealing member was peeled off, it was difficult to seal the opening again, and there was a risk that blood contamination would occur.
  • an object of the present invention is to collect serum by an automatic serum collection device without using a rubber stopper as a sealing member and without having to remove a rubber stopper. With this force, even after the sealing member is removed, the blood collection tube can be sealed again to prevent blood contamination. Provide a blood collection tube. Disclosure of the invention
  • FIG. 1 is a partial sectional view showing one embodiment of a blood collection tube of the present invention.
  • FIG. 2 is a perspective view of a blood collection tube holder to which a blood collection tube is attached and the blood vessel of the present invention.
  • FIGS. 3a and 3b are exploded perspective views of a blood collection tube holder and a blood collection needle to which a blood collection tube is attached.
  • FIG. 4 is a cross-sectional view showing a state where the blood collection tube of the present invention is mounted on a blood collection tube holder, a blood collection needle, and the like.
  • 5a and 5b are perspective views showing the use state of the blood collection tube of the present invention.
  • the blood collection tube 1 of the present invention includes a bottomed tube 2 having one end opened and the other end closed, a film-shaped sealing member 4 attached to the opening of the bottomed tube 2, and A cap 6 is provided detachably on the outer wall of the bottom of the bottom tube 2 and can be fitted to the opening of the bottomed tube 2.
  • FIG. 1 is a partial cross-sectional view showing a blood collection tube of the present invention.
  • the blood collection tube 1 is adhered to the bottomed tube 2 having one end opened and the other end closed, the anticoagulant 3 contained in the bottomed tube 2, and the open end of the bottomed tube 2.
  • the blood collection tube 1 is tightly closed by the film-shaped sealing member 4.
  • O Closed bottomed tube-2 is preferably a reduced-pressure blood collection tube whose pressure has been reduced by a predetermined amount according to the amount of blood collected o
  • the bottomed tube 2 is a test tube having an open end.
  • the materials used for forming the bottomed tube 2 include glass, attri-opened 2-trile resin, polyethylene terephthalate, polyarate, and the like.
  • Test tube made of plastic with gas barrier properties such as mid-pressure, poly-styrene, or poly-styrene, or poly-hole
  • a material coated with a gas-barrier-like substance such as polyvinylidene chloride, polyvinyl alcohol, etc. is used on the surface.
  • the opening side of the bottomed tube 2 is slightly narrower, and a threaded portion 7 to which a cap 6 can be screwed is provided on the outer peripheral surface of the narrowed portion. .
  • a screw portion 8 to which a cap 6 can be screwed is provided also at the bottom of the bottomed tube 2.
  • the cap 6 is usually
  • the bottomed pipe 2 is screwed to a thread 8 provided on the outer wall of the bottom of the pipe. When necessary, it is removed from the bottom of the pipe, screwed into a thread 7 provided on the outer peripheral surface on the opening side of the bottomed pipe 2, and removed by a sheet material 9 in a cap 6.
  • Anticoagulant 3 is used to prevent blood after blood collection from being collected in blood collection tube 1 and to prevent clotting during testing, for example, -EDTA-2K Etc. are used o
  • the film-shaped sealing member 4 is formed in a circular shape having a diameter slightly larger than the outer diameter of the opening of the bottomed tube 2 ′: film-shaped sealing For member 4, aluminum foil and various films were vacuum evaporated.
  • film-shaped sealing For member 4 aluminum foil and various films were vacuum evaporated.
  • ____________________________________________________ or various types of phenolic such as polyvinylidene chloride, polyvinyl alcohol, ethylene vinyl alcohol It is made up of coated snorkeling materials.
  • the film-shaped sealing member 4 is made of a plastic material such as polyethylene terephthalate, polyamide, or the like, which has gas barrier properties. It may be composed of sticks.
  • the resealable rubber member 5 is formed in a circular shape having substantially the same shape as the inner diameter of the opening of the bottomed tube 2, and is made of synthetic rubber, natural rubber, and thermoplastic elastomer. And is fixed on the film-shaped sealing member 4 with an adhesive or the like. Further, the resealable rubber member 5 may be fixed to the lower surface of the film-shaped sealing member 4 instead of the upper surface.
  • the resealable rubber member 5 is stimulated by a blood collection needle or the like of a blood collection device, and has a function of closing a stimulating hole and resealing the blood collection tube after being removed. ing .
  • Cap 6 has screw grooves 9 and a on its inner peripheral surface so that it can be screwed to the threads (threads) 7 and 8 of the bottomed tube 2. are doing . Further, a sealing material 9 for sealing the opening of the bottomed tube 2 is stored on the bottom surface of the cap 6.
  • the seal material 9 is formed of an elastic body such as rubber.
  • the cap 6 is formed of plastic, rubber, inorganic materials, and metals. As a material for the cap 6, a plus-chip is preferable from the viewpoint of ease of molding and cost.
  • the cap 6 is attached to the bottom of the bottomed pipe 2 in an airtight state.
  • the cap 6 is attached to the opening of the bottomed tube 2
  • blood can be prevented from being contaminated by deposits on the inner surface of the cap 6.
  • a sealant is provided between the open end of the cap 6 and the bottomed pipe. (For example, a thin film of RTV silicone rubber) and peeling around the bottom of the bottomed tube 2 with the cow cap 6.
  • Possible or severable Heat-shrinkable tubing eg, polystyrene, borlet tip
  • the blood collection tube 1 is used by being inserted into a blood collection holder 11 to which a blood collection needle 10 is attached as shown in FIG.
  • the blood collection needle 10 penetrates the piercing needle portion 12 for stimulating a blood vessel, the re-sealing member 5 and the film-shaped sealing member 4.
  • a screw 14 a capable of screwing a blood sampling holder 1 U is screwed and provided, as shown in FIG.
  • the case cap 17 is attached to the lumber piercing section 13, and the case cap 18 is attached to the piercing needle section 12, respectively. .
  • a blood collection needle 10 is screwed into the blood collection tube holder 11 as shown in the second passage. Then, the puncture needle portion 12 of the blood collection needle 10 is pierced into the blood vessel. Further, the blood collection tube 1 is inserted into the blood collection tube holder 11, and as shown in FIG. 4, the sealing member stimulating portion 13 is provided with a rubber chip 16 and a resealing device. Insert the flexible rubber member 5 and the film-shaped sealing member 4 until they are pierced. If the pressure in the blood collection tube 1 is reduced, blood according to the degree of decompression in the blood collection tube is collected from the blood vessel. The blood in the blood collection tube 1 collected in this manner is collected by an automatic serum collection device or the like, and is subjected to various blood tests.
  • the film-shaped sealing member 4 of the blood collection tube 1 must be resealed.
  • the blood in the blood collection tube 1 is collected by a method such as piercing and decantation, and various types of blood are collected.
  • Perform a blood test If it is necessary to tightly close the blood collection tube 1 after the sampling operation, as shown in Fig. 5a, a key screwed into the thread 8 of the outer wall _ of the bottomed tube 2 as shown in Fig. 5a Remove the cap 6 and screw the cap 6 into the screw _ on the opening side of the bottomed pipe 2 as shown in Fig. 5b, and seal the bottomed pipe 2 You This can prevent foreign substances from entering the blood collected in the blood collection tube 2 from the outside, and can also prevent blood from flowing out from the blood collection tube. Pollution can be reduced. Industrial applicability
  • the blood collection tube of the present invention includes a bottomed tube having one end open and the other end closed, and a film-shaped seal attached to the opening of the bottomed tube.
  • a member and a cap detachably mounted on the outer wall of the bottom of the bottomed tube, and a cap which can be fitted into the opening of the bottomed tube, so that whole blood or Collection of serum after centrifugation can be performed manually or automatically using a collection needle, etc. Even after the blood has been collected by the method, the opening of the blood collection tube can be sealed, if necessary, with a cap attached to the bottom of the bottomed tube. .
  • the blood inside the blood collection tube is less likely to be contaminated from the outside, and the blood in the blood collection tube is prevented from flowing out to the outside. Can be reduced.
  • the blood collection tube is provided with a film-shaped sealing member that does not use a rubber stopper, if necessary, remove the film-shaped sealing member. The opening can be sealed even afterwards, so that it can be used for a wide range of purposes.

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
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  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medical Informatics (AREA)
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  • Chemical & Material Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Analytical Chemistry (AREA)
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  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

This invention relates to a blood collecting tube consisting of a bottomed tube one of the ends of which is open and the other end of which is closed, a film-like sealing member fitted on the opening of the bottomed tube and a cap which is disposed removably on the outer wall of the bottom of the bottomed tube and can be fitted on the opening of the bottomed tube. Thus the opening of the blood collecting tube can be sealed with the cap even after the film-like sealing member is removed and it is possible to prevent the contamination of the blood inside the blood collecting tube from outside and the contamination by the outflow of the blood inside the blood collecting tube.

Description

曰月 田 採 血 管  Wangetsu Blood Collection Tube
V. ' 技術分野 — V. '' Technical Fields —
. 本発明は、 採血管 に関す る 。 詳 し く は、 有底管の開 口 フ ィ ル ム 状封止部材を被着 し た採血管 に関す る 。 背景技術  The present invention relates to a blood collection tube. More specifically, the present invention relates to a blood collection tube to which a film-like sealing member having an open bottomed tube is adhered. Background art
病院等の臨床検査の際に行われて い る 従来の採血 シス テ ム にお い て は 、 血清検査用、 血球検査用、 血糖値検査用、 凝固因子検査用等の数種類の減圧採血管を用 い て い る 。 こ れら数種類の採血管.と 通常マ ル チ針 と い わ れ t い る 1 本 の 採血針に よ り 、 _ 被検診者か ら 数回 に わ た る 採血操作を行 つ て、 必要な血液試 _料を得て い た。  In a conventional blood collection system used for clinical tests at hospitals and the like, several types of decompressed blood collection tubes for serum tests, blood cell tests, blood glucose tests, and coagulation factor tests are used. Used. These several types of blood collection tubes, and one blood collection needle, usually called a multi-needle, are used to perform blood collection operations several times from the subject to be examined. Blood sample was obtained.
そ の傺使用 さ れ る 採血管、 例 え ば減圧採血管 は 、 ガ ラ ス ま た はプ ラ ス チ ッ ク 製の有底管 と ゴ ム 栓 と 力、 ら 構成 さ れて い る 。 しか し 、 自動血清分取装置を使用す る 場 合 は 、 ゴ ム -栓を外す こ と な く 、 そ の ま ま 自動血清採取装置 を用 い て血 清を採取す る こ と がで き る 減圧採血管が好 ま し い。 そ の よ う な採血管 と し て は、 有底管の開 口 に 、 ゴ ム 栓の'かわ り に 自動血清分取装置の採取針を 直接剌通 し う る フ ィ ル ム 状封 止部材^被着 し て 、 外部か ら の汚染 を 防止 し た 減圧採血管 か あ る 。 し か し なが ら 、 血液検査に は種々 の項目 があ り 、 上述の よ う な減圧採血管で採血 し た場合で あ つ て も 、 自動血清分 取装置を使用 し な いで 、 フ イ ル ム 状封止部材を剥が し て血 清を採取す る こ と があ る 。 し 力、 し、 上述の よ う な ゴ ム 栓を 不要 と し た减圧採血管で は、 血液を従来の よ う な ピぺ ッ τ ィ ン グ、 デカ ン テ ― シ ョ ン と い つた方法に よ り 採取す る た め に は、 有底管の開口 を密閉 し てい る フ ィ ル厶状封止部材を 剥がす こ とが必要であ る 。 し か し 、 一度封止部材を剥がす と 、 再度開 口 を密閉す る こ と が困難 と な り 、 血液汚染が生 ず る恐れがあ つ た。 The blood collection tube used, for example, a vacuum blood collection tube, is composed of a bottomed tube made of glass or plastic, a rubber stopper, and a force. However, when using an automatic serum collection device, the serum can be collected using the automatic serum collection device without removing the rubber stopper. Decompression blood collection tubes are preferred. Such a blood collection tube is a film-like seal that allows the collection needle of an automatic serum collection device to directly penetrate the opening of the bottomed tube instead of the rubber stopper. There is a reduced-pressure blood collection tube that is attached to a member to prevent external contamination. However, there are various items in the blood test, and even when blood is collected using a reduced-pressure blood collection tube as described above, a blood test must be performed without using an automatic serum collection device. The serum may be collected by peeling the rubber-shaped sealing member. In a low-pressure blood collection tube that does not require a rubber stopper as described above, the blood is called a conventional pi wing and decantation. In order to collect by the method, it is necessary to peel off the film-like sealing member that seals the opening of the bottomed pipe. However, once the sealing member was peeled off, it was difficult to seal the opening again, and there was a risk that blood contamination would occur.
そ こ で、 本発明の 目的は、 封止部材 と し て ゴ ム栓を用 い ず、 よ つ て ゴム栓を取 り 外す必要な く 自動血清分取装置 に よ る 血清の採取を行 う こ と 力 で き 、 さ ら に、 封止部材を取 り 外 した後にあ っ て も 、 再度採血管を封止ず る こ と がで き 、 血液の汚染を防止す る こ と がで き る 採血管を提供す る も の で め る-。 発明の開示  Therefore, an object of the present invention is to collect serum by an automatic serum collection device without using a rubber stopper as a sealing member and without having to remove a rubber stopper. With this force, even after the sealing member is removed, the blood collection tube can be sealed again to prevent blood contamination. Provide a blood collection tube. Disclosure of the invention
本発明は、 一端が開口 し他端が閉塞 し た有底管と、 該有 底管の開口 に被着 ざれた フ ィ ル ム状封止部材 と 、 前記有底 管の管底外壁に着脱可能 設け ら れ る と 共 に前記有底管 の 開口 に嵌着可能な キ ャ ッ プ と を有す る も の で あ る & 図面の簡単な説明 第 1 図 は 、 本発明の採血管の一実施例—を示す部分断面図 で あ る 。 第 2 図 は、 採血管が装着 さ れ る 採血管 ホ ル ダ 一 お よ び本発明の探血管の斜視図で あ る 。 第 3 a 図お よ び第 3 b 図 は、 採血管が装着 さ れ る 採血管 ホ ル ダ一お よ.び採血針 の 分解斜視図で あ る 。 第 4 図は、 本発明の採血管が採血管 ホ ル ダ— お よ び採血針等に装着 さ れた状態を示す断面図で あ る 。 第 5 a 図お よび第 5 b 図 は、 本発明の採血管の使用 状態を示す斜視図であ る。 発明 を実施す る た め の最良の形態 以下、 本発明の実施例を図面に基づい て詳述す る 。 The present invention provides a bottomed pipe having one end opened and the other end closed, a film-shaped sealing member attached to the opening of the bottomed pipe, and a detachable attachment / detachment to a pipe bottom outer wall of the bottomed pipe. Capable of being provided and having a cap that can be fitted into the opening of the bottomed pipe & brief description of the drawings. FIG. 1 is a partial sectional view showing one embodiment of a blood collection tube of the present invention. FIG. 2 is a perspective view of a blood collection tube holder to which a blood collection tube is attached and the blood vessel of the present invention. FIGS. 3a and 3b are exploded perspective views of a blood collection tube holder and a blood collection needle to which a blood collection tube is attached. FIG. 4 is a cross-sectional view showing a state where the blood collection tube of the present invention is mounted on a blood collection tube holder, a blood collection needle, and the like. 5a and 5b are perspective views showing the use state of the blood collection tube of the present invention. BEST MODE FOR CARRYING OUT THE INVENTION Hereinafter, embodiments of the present invention will be described in detail with reference to the drawings.
本発明の採血管 1 は、 一端が開 口 し 他端が閉塞 し た有底 管 2 と 、 有底管 2 の開 口 に被着 さ れた フ ィ ル ム 状封止部材 4 と 、 有底管 2 の管底外壁に着脱可能に設け ら れ る と 共 に 有底管 2 の開 口 に嵌着可能な 丰 ャ ッ プ 6 と を有 し て い る 。  The blood collection tube 1 of the present invention includes a bottomed tube 2 having one end opened and the other end closed, a film-shaped sealing member 4 attached to the opening of the bottomed tube 2, and A cap 6 is provided detachably on the outer wall of the bottom of the bottom tube 2 and can be fitted to the opening of the bottomed tube 2.
第 1 図は、 本発明の採血管を示す部分断面図で あ る 。 採 血管 1 は、 一端が開口 し 他端が閉塞 し た有底管 2 と 、 有底 管 2 内に収納 さ れた抗凝固剤 3 と 、 有底管 2 の開 _口端 に被 着 さ れ る と 共に有底管 2 内を気密 に密閉す る フ イ ル ム 状封 止部材 4 と 、 フ ィ ル ム状封止部材 4 上 に設 け ら-れた再 シ ― ル性 ゴ ム 部材 5 と 、 有底管 2 の管底外壁 に着脱可能 に設 け ら れ る と 共 に有底管 2 の開 口 に着脱可能に設 け ら れ る 牛 ャ. プ 6 と か ら 構成 さ れて い る 。  FIG. 1 is a partial cross-sectional view showing a blood collection tube of the present invention. The blood collection tube 1 is adhered to the bottomed tube 2 having one end opened and the other end closed, the anticoagulant 3 contained in the bottomed tube 2, and the open end of the bottomed tube 2. A film-shaped sealing member 4 for hermetically sealing the inside of the bottomed pipe 2 together with the bottomed tube 2, and a re-sealing rubber provided on the film-shaped sealing member 4. It is composed of a member 5 and a cow cap 6 which is detachably attached to the outer wall of the bottomed tube 2 and detachably attached to the opening of the bottomed tube 2. It is.
そ して、 採血管 1 は 、 フ ィ ル ム 状封止部材 4 に よ っ て密 閉 さ れた有底管— 2 内が採血量に応 じ て所定量減圧 さ れた減 圧採血管 と な -っ て い る こ と が好 ま し い o The blood collection tube 1 is tightly closed by the film-shaped sealing member 4. O Closed bottomed tube-2 is preferably a reduced-pressure blood collection tube whose pressure has been reduced by a predetermined amount according to the amount of blood collected o
有底管 2 は、 第 1 図に示すよ う に、 一端が開口 し た試験 管状の も のであ る 。 有底管 2 の形成に使用 さ れ る 材質 と し ては、 ガ ラ ス 、 ア タ リ 口 二- ト リ ル系樹脂、 ポ リ ヱ チ レ ン テ レ フ 夕 レ ー ト 、 ポ リ ア ミ ド 、 —ボ リ ィ ミ ド等の ガス バ リ ヤ ー 性を有す る プ ラ ス チ ッ ク 、 ま た ポ リ ス チ レ ン 、 ポ リ プ 口 ピ レ ン等によ り 試験管状に形成 して その表面に ポ リ 塩化 ビ 二 リ デ ン 、 ボ リ ビ ニ ルァ ル コ ー ル等 © ガス バ リ ャ一性物質を コ ー ト した も のな どが使用 さ れ:る。 こ の有底管 2 の開 口側 はやや細 く な つ てお り 、 細 ぐな つ た部分の外周面に、 キ ヤ ッ プ 6 が螺着可能な ネ ジ部 7 が設け ら れてい る 。 ま た、 有底 管 2の管底部に も 、 キ ャ ヅ— ノ 6 が螺着可能な ネ ジ部 8 が設 け ら れて い る o ■ ャ ' ャ ッ プ 6 は、 通常時に は、 有底管 2 の管 底外壁部に設け ら れた ネ ジ部 8 に螺着 ざれてい る 。 必要時 に、 管底部か ら取 り 外 し 、 有底管 2 の開口側外周面に設け ら れた ネ ジ部 7 に螺着 し 、 キ ャ ッ プ 6 内の シ一ノレ材 9 に よ り 有底管 2 内を密閉す- る o  As shown in FIG. 1, the bottomed tube 2 is a test tube having an open end. The materials used for forming the bottomed tube 2 include glass, attri-opened 2-trile resin, polyethylene terephthalate, polyarate, and the like. Test tube made of plastic with gas barrier properties such as mid-pressure, poly-styrene, or poly-styrene, or poly-hole A material coated with a gas-barrier-like substance such as polyvinylidene chloride, polyvinyl alcohol, etc. is used on the surface. The opening side of the bottomed tube 2 is slightly narrower, and a threaded portion 7 to which a cap 6 can be screwed is provided on the outer peripheral surface of the narrowed portion. . In addition, a screw portion 8 to which a cap 6 can be screwed is provided also at the bottom of the bottomed tube 2. o The cap 6 is usually The bottomed pipe 2 is screwed to a thread 8 provided on the outer wall of the bottom of the pipe. When necessary, it is removed from the bottom of the pipe, screwed into a thread 7 provided on the outer peripheral surface on the opening side of the bottomed pipe 2, and removed by a sheet material 9 in a cap 6. O Close the bottomed pipe 2 o
抗凝固剤 3 は、 採血後の血液が採血管 1 内に お い て、 若 し ぐ ば検査中に凝固 し な い よ う にす る ため の も の で、 例え ば、- E D T A - 2 K 等が使用 さ れ る o  Anticoagulant 3 is used to prevent blood after blood collection from being collected in blood collection tube 1 and to prevent clotting during testing, for example, -EDTA-2K Etc. are used o
フ ィ ル ム状封止部材 4 は 、 有底管 2 'の開口 の 外怪よ り や や大 き な径を有す る 円形状に形成 さ れて い る : フ ィ ル ム 状 封止部材 4 は、 了 ル ミ 箔、 各種 フ イ ル ム に ァ ル ミ 蒸着 し た も の、 _ ま た各種 フ ィ ノレ ム に ポ リ 塩化 ビ 二 リ デ ン、 ポ リ ビ 二 ル ア ル コ ー ル 、 ェ チ レ ン ビ ニ ル ァ ル コ 一 ル 共重合体等 の ガ スノ リ ャ —性素材を コ — ト し た も の に よ り 構成 さ れ て い る 。 ま た、 フ ィ ル ム 状封止部材 4 は ポ リ エ チ レ ン テ レ フ タ レ 一 ト 、 ポ リ ァ ミ ド等の素材 自体がガ ス バ リ ヤ ー性を有す る プ ラ ス チ ッ ク に よ り 構成 し て も 良い。 再 シ一 ル性 ゴ 厶 部材 5 は、 有底管 2 の開 口 の内径 と 略同型を有す る 円形状 に形 成 さ れ、 合成 ゴ ム 、 天然ゴムお よ び熱可塑性 エ ラ ス ト マ一. 等:に よ り 形成 さ れ、 フ イ ル ム 状封止部材 4 の上 に接着剤等 を甩いて固着 さ れてい る 。 ま た、 再 シ ー ル性 ゴ厶 部材 5 は 、 フ ィ ル ム 状封止部材 4 の上面で な く 、 下面 に 固着 し て も よ い 。 再 シ一ル性 ゴ ム 部材 5 は、 採血器具 の採血針等 に よ り 剌通さ れ、:抜去 さ れた後 に、 剌通孔を 閉塞 し 、 採血管内 を 再び密閉す る機能を有 し て い る 。 The film-shaped sealing member 4 is formed in a circular shape having a diameter slightly larger than the outer diameter of the opening of the bottomed tube 2 ′: film-shaped sealing For member 4, aluminum foil and various films were vacuum evaporated. In addition, _____________________________________________ or various types of phenolic such as polyvinylidene chloride, polyvinyl alcohol, ethylene vinyl alcohol It is made up of coated snorkeling materials. The film-shaped sealing member 4 is made of a plastic material such as polyethylene terephthalate, polyamide, or the like, which has gas barrier properties. It may be composed of sticks. The resealable rubber member 5 is formed in a circular shape having substantially the same shape as the inner diameter of the opening of the bottomed tube 2, and is made of synthetic rubber, natural rubber, and thermoplastic elastomer. And is fixed on the film-shaped sealing member 4 with an adhesive or the like. Further, the resealable rubber member 5 may be fixed to the lower surface of the film-shaped sealing member 4 instead of the upper surface. The resealable rubber member 5 is stimulated by a blood collection needle or the like of a blood collection device, and has a function of closing a stimulating hole and resealing the blood collection tube after being removed. ing .
キ ヤ ツ プ 6: は、 有底管 2 の ネ ジ部 ( ネ ジ山) 7 お よ び 8 に螺着可能.な よ う に、 そ の 内周面 に ネ ジ溝 9· aを有 し て い る 。 'ま た、 キ ャ ッ プ 6 の底面 に は、 有底管 2 の 開 口 を封止 す る た め の シ 一 ル材 9 が収納 さ れて い る 。 シ 一 ル材 9 は 、 ゴ 厶 等の弾性体 に よ り 形成 さ れて い る 。 キ ャ ッ プ 6 は、 プ ラ ス チ ッ ク 、 ゴ ム、 無機材料お よ び金'属 な ど に よ り 形成 さ れ る 。 キ ヤ ッ プ 6 の材料 と し て は 、 成形の容易性、 コ ス ト 性等か ら プ ラ ス -チ ッ ク が好適で あ る。  Cap 6: has screw grooves 9 and a on its inner peripheral surface so that it can be screwed to the threads (threads) 7 and 8 of the bottomed tube 2. are doing . Further, a sealing material 9 for sealing the opening of the bottomed tube 2 is stored on the bottom surface of the cap 6. The seal material 9 is formed of an elastic body such as rubber. The cap 6 is formed of plastic, rubber, inorganic materials, and metals. As a material for the cap 6, a plus-chip is preferable from the viewpoint of ease of molding and cost.
ま た、 キ ャ ッ プ 6 は 、 有底管 2 の底部 に 気密状態 に取 り 付 け ら れ て い る こ と 力く 好 ま し い 。 こ の よ う に す る こ と に よ り 、 有底管 2 の底部 よ り キ ヤ ") プ 6 を取 り 外す ま で の 間、 キ ャ ッ プ 6 の内面、 —特 に底面 'に雑菌等の付着 を防止する こ と がで き 、 —有底管 2 の開口 に キ ャ ツ プ 6 を取 り 付けた と き に 、 血 液が、 ヰ ャ ッ プ 6 の内面の付着物に よ り 汚染 さ れ る こ と を 防止で き る 。 キ ヤ ッ プ 6 を有底管 2 の底部に気密 に取 り 付 け る方法と し て は、 キ ャ ツ プ 6 の開 ¾端部 と有底管 と の間 に 、 シ 一 ル剤 (例え ば、 R T V シ リ コ ー ン ゴ 厶 の薄膜) を 被着す る こ と 、 また、 牛ャ ッ プ 6.を取 り 付けた状態で、 有 底管 2 の底部の外周 に、 剥離可能 ま た は切断可能 [切断用 の脆弱部 (例え ば、 ミ シ ン 目 ) ] 部分 を有す る 熱収縮チ ュ 一ブ (例え ば、 ポ リ ェ チ レ ン 、 ボ リ プ 口 ピ レ ン な どの延伸 チ ュ ー ブ ) を被嵌す る こ と な どが考え ら れる 。 Further, it is strongly preferable that the cap 6 is attached to the bottom of the bottomed pipe 2 in an airtight state. By doing this, Until the cap 6 is removed from the bottom of the bottomed pipe 2), it is possible to prevent bacteria and the like from adhering to the inner surface of the cap 6, especially to the bottom surface. —When the cap 6 is attached to the opening of the bottomed tube 2, blood can be prevented from being contaminated by deposits on the inner surface of the cap 6. As a method of airtightly attaching the cap 6 to the bottom of the bottomed pipe 2, a sealant is provided between the open end of the cap 6 and the bottomed pipe. (For example, a thin film of RTV silicone rubber) and peeling around the bottom of the bottomed tube 2 with the cow cap 6. Possible or severable Heat-shrinkable tubing (eg, polystyrene, borlet tip) that has a [fragile part for cutting (for example, perforation)] portion Stretching Tube) may be inserted.
採血管 1 は、 第 2 図 に示すよ う に採血針 10を取 り 付 けた 採血ホ ル ダ一 11内に差 し込んで使用 さ れ る 。 採血針 10は、 第 3 b 図に示す よ う に 、 血管を剌通す る 穿剌針部 12と 、 再 シ ー ル性部材 5 お よ びフ ィ ル ム状封止部材 4 を剌通す る 封 止部.材剌通部 13と、 ごれ ら穿剌針部 12お よ び封止部材剌通 部 Uを夫々 支持す る 針基部 14と 、 封止部材剌通部 13を被包 す る ゴ ム チ ッ プ 16と か ら成る 。 こ の封止部材剌通—部 13に-隣 接 し た針基部 14の外周面に は採血ホ ル ダ一 1Uこ螺着可能な ネ ジ 14aが刻:設 さ れ、 第 3 a 図に示す採血管ホ ル ダ一 11の 針接台部 15に螺着 さ れ る ゴ ム チ ッ プ iSほ、· 薄い ゴ ム 製で—、 先端が封.止 さ れ た チ ュ 一ブ体であ:る :, ま た 、 採血針 10は 、 使用前 に は 、 第 3 a 図お よ び 3 b 図 に示す よ う に 、 封止部 材剌通部 1 3に は ケ ー ス キ ャ ッ プ 1 7が、 穿剌針部 1 2に'は プ 口 テク 夕 一 1 8か'、 そ れぞれ取 り 付 け ら れて い る 。 The blood collection tube 1 is used by being inserted into a blood collection holder 11 to which a blood collection needle 10 is attached as shown in FIG. As shown in FIG. 3b, the blood collection needle 10 penetrates the piercing needle portion 12 for stimulating a blood vessel, the re-sealing member 5 and the film-shaped sealing member 4. Sealing part, enclosing the material piercing part 13, the needle piercing part 12 and the needle base 14 which supports the sealing member stimulating part U, respectively, and the sealing member stimulating part 13 It consists of a rubber chip 16. On the outer peripheral surface of the needle base 14 which is adjacent to the sealing member piercing section 13, a screw 14 a capable of screwing a blood sampling holder 1 U is screwed and provided, as shown in FIG. A rubber chip iS screwed to the needle holder 15 of the blood collection tube holder 11 shown in the drawing, made of thin rubber, and sealed at the tip. Before use, the blood collection needle 10 should be sealed as shown in Figs. 3a and 3b. The case cap 17 is attached to the lumber piercing section 13, and the case cap 18 is attached to the piercing needle section 12, respectively. .
次に、 本発明の採血管の使用方法 に つ い て説明す る 。  Next, a method of using the blood collection tube of the present invention will be described.
ま ず、 第 2通に示す よ う に採血管 ホ ル ダ ー 1 1に採血針 1 0を 螺着す る 。 そ し て 、 採血針 1 0の穿刺針部 1 2を血管 に穿剌す る 。 さ ら に、 採血管 1 を採血管 ホ ル ダ ー 1 1内 に挿入 し 、 第 4 図 に示す よ う に、 封止部材剌通部 1 3が ゴ ム チ ッ プ 1 6、 再 シ一ル性 ゴム 部材 5 およ び フ ィ ル ム状封止部材 4 を剌通す る ま で挿入す る 。 採血管 1 内が減圧 さ れて い れば、 採血管 内の減圧度に応 じ た血液が血管か ら 採血 さ れ る 。 こ の よ う に して採血 さ れた採血管 1 内の血液 は、 自動血清分取装置 等 に よ り 採取 さ れ、 各種血液検査に供 さ れ る 。 ま た、 こ の 自動血清分取装置を使甩 し ない で血液採取を行い、 血液検 査を行 う 場合 に は、 採血管 1 の フ ィ ル ム 状封止部材 4 を再 シ ― ル性 ゴ ム 部材 -5 と共 に剥力 し て、 ピ ぺ ッ テ ィ ン グ お よ びデ カ ン テ 一 シ ョ ン等の方法 に よ り 採血管 1 内の血液を採 取 して 、 各種血液検査を行 う 。 採取作業後、 採血管 1 を密 閉す る 必要があ る 場合 は、 第 5 a 図 に示す よ う に 、 有底管 2 の管底外壁 _部の ネ ジ部 8 に螺蕾さ れた キ ャ ッ プ 6 を外 し 、 第 5 b 図 に示す よ う に、 キ ヤ ッ プ 6 を有底管 2 の開 口側 ネ _ ジ部 Ί に螺着 し て-、 有底管 2 を密閉す る 。 こ れ に よ り 、 採 血管 2.内 に採取 さ れた血液中 に外部よ り 異物が混入す る こ と を 防止で き 、 ざ ら に 、 採血管内 の血液の流出 を 防止で き 、 血液汚染を減少 さ せ る こ と が で き る 。 産業上の利用可能性 First, a blood collection needle 10 is screwed into the blood collection tube holder 11 as shown in the second passage. Then, the puncture needle portion 12 of the blood collection needle 10 is pierced into the blood vessel. Further, the blood collection tube 1 is inserted into the blood collection tube holder 11, and as shown in FIG. 4, the sealing member stimulating portion 13 is provided with a rubber chip 16 and a resealing device. Insert the flexible rubber member 5 and the film-shaped sealing member 4 until they are pierced. If the pressure in the blood collection tube 1 is reduced, blood according to the degree of decompression in the blood collection tube is collected from the blood vessel. The blood in the blood collection tube 1 collected in this manner is collected by an automatic serum collection device or the like, and is subjected to various blood tests. Also, when blood is collected without using this automatic serum collection device and a blood test is performed, the film-shaped sealing member 4 of the blood collection tube 1 must be resealed. By peeling together with the rubber member -5, the blood in the blood collection tube 1 is collected by a method such as piercing and decantation, and various types of blood are collected. Perform a blood test. If it is necessary to tightly close the blood collection tube 1 after the sampling operation, as shown in Fig. 5a, a key screwed into the thread 8 of the outer wall _ of the bottomed tube 2 as shown in Fig. 5a Remove the cap 6 and screw the cap 6 into the screw _ on the opening side of the bottomed pipe 2 as shown in Fig. 5b, and seal the bottomed pipe 2 You This can prevent foreign substances from entering the blood collected in the blood collection tube 2 from the outside, and can also prevent blood from flowing out from the blood collection tube. Pollution can be reduced. Industrial applicability
以上詳述 した よ う に、 本発明の採血管 は、 一端が開 σ し 他端が閉塞 し た有底管 と、 該有底管の開口 に被着 さ れた フ ィ ル ム状封止部材 と 、 前記有底管の管底外壁に着脱可能に設 け ら れる.と 共に前記有底管の開口 に嵌着可能な キ ヤ ッ プ と を備えてい る ので、 全血若 し く は遠心分離後の血清の採取 は、 採取針等を用 い て手動若 し く は 自動で行 う こ と がで き る と共に、 フ ィ ル ム伏封止部ネオを取 り 去 っ て種々 の方法で 血液を採取し た後で も 、 必要に応 じて有底管の管底に取付 け ら れてい る キ ャ ッ プを用いて、 採血管の開口 を密閉す る こ と がで き る 。 従 っ て、 採血管内部の血液が外部か ら 汚染 ざれ る こ と が少な く 、 ま た、 逆に採血管內部の血液が外部 に流出す る こ-と を防止す る の で 、 血液汚染を少な く す る こ と がで き る 。 さ ら に、 ゴム 栓を用 い な い フ ィ ル ム状封止部 材を備え る 採血管であ り なが ら 、 必要に応 じ て フ _ィ ル 厶状 封止部材を:剥が し た後で あ っ て も 開口を密閉す る こ と がで き-る か ら 、 広い愿途に使用す る こ と がで き る 。  As described above in detail, the blood collection tube of the present invention includes a bottomed tube having one end open and the other end closed, and a film-shaped seal attached to the opening of the bottomed tube. A member and a cap detachably mounted on the outer wall of the bottom of the bottomed tube, and a cap which can be fitted into the opening of the bottomed tube, so that whole blood or Collection of serum after centrifugation can be performed manually or automatically using a collection needle, etc. Even after the blood has been collected by the method, the opening of the blood collection tube can be sealed, if necessary, with a cap attached to the bottom of the bottomed tube. . Therefore, the blood inside the blood collection tube is less likely to be contaminated from the outside, and the blood in the blood collection tube is prevented from flowing out to the outside. Can be reduced. In addition, while the blood collection tube is provided with a film-shaped sealing member that does not use a rubber stopper, if necessary, remove the film-shaped sealing member. The opening can be sealed even afterwards, so that it can be used for a wide range of purposes.

Claims

請 求 の 範 囲 . 一端が開 口 し 他端が閉塞 し た有底管 と 、 該有底管の開 口 に被着 ざ れた フ ィ ル ム 状封止部材 と 、 前記有底管の管 底外壁に着脱可能に設け ら れ る と 共 に前記有底管の開口 に嵌着可能な牛 ャ ッ プ と を有す る こ と を特徴 と す る 採血 管。 _ A bottomed pipe having one end opened and the other end closed, a film-shaped sealing member attached to the bottomed tube opening, and a bottomed tube. A blood collection tube characterized by having a cow cap detachably provided on an outer wall of a tube bottom and capable of being fitted into an opening of the bottomed tube. _
. 前記有底管内が、 減圧 さ れて い る 請求の範囲 1 に記載 の採血管。 The blood collection tube according to claim 1, wherein the pressure in the bottomed tube is reduced.
. 前記 フ ィ ル ム 状封止部材は、 再 シ一ル性 ゴ ム 部材を有 し てい る 請求の範囲 1 ま た は 2 に記載の採血管。 3. The blood collection tube according to claim 1, wherein the film-shaped sealing member has a re-sealing rubber member.
. 前記有底管は、 有底管の開口端外壁 に設け ら れた第 1 の ネ ジ部と 、 有底管の管底部に設け ら れた第 2 の ネ ジ部 と を有 し 、: 前記キ ヤ ッ プは該第 1 の ネ ジ部お よ び第 2 の ネ ジ部 と螺合す る ネ ジ溝を有 し て い る 請求の範囲 1 に記 載の採血管。 . . The bottomed tube has a first screw portion provided on the outer wall of the open end of the bottomed tube, and a second screw portion provided on the bottom of the bottomed tube; 2. The blood collection tube according to claim 1, wherein the cap has a screw groove that is screwed with the first screw portion and the second screw portion. .
. 前記 フ ィ ル ム 状封止部材 は、 ガ ス バ リ ヤ 一性 フ ィ ル ム か ら な る 請求の範囲 1 に記載の採血管。 2. The blood collection tube according to claim 1, wherein the film-shaped sealing member is made of a gas-barrier film.
PCT/JP1988/000746 1987-07-27 1988-07-26 Blood collecting tube WO1989000830A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU20825/88A AU2082588A (en) 1987-07-27 1988-07-26 Blood collecting tube

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP1987114851U JPH034250Y2 (en) 1987-07-27 1987-07-27
JP62/114851U 1987-07-27

Publications (1)

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WO1989000830A1 true WO1989000830A1 (en) 1989-02-09

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WO (1) WO1989000830A1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4217104A1 (en) * 1992-05-22 1993-11-25 Salama Magdy Reservoir or reservoir system - for inactivation, inhibition and/or elimination of pathogens

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59230539A (en) * 1983-01-27 1984-12-25 ツェ−・ア−・グライナ−・ウント・シェ−ネ・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツンク Blood sample collecting tube
JPS62160908U (en) * 1985-12-19 1987-10-13

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59230539A (en) * 1983-01-27 1984-12-25 ツェ−・ア−・グライナ−・ウント・シェ−ネ・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツンク Blood sample collecting tube
JPS62160908U (en) * 1985-12-19 1987-10-13

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4217104A1 (en) * 1992-05-22 1993-11-25 Salama Magdy Reservoir or reservoir system - for inactivation, inhibition and/or elimination of pathogens

Also Published As

Publication number Publication date
JPH034250Y2 (en) 1991-02-04
JPS6420810U (en) 1989-02-01

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