WO1988003021A3 - Treatment of gingivitis with ibuprofen or flurbiprofen - Google Patents

Treatment of gingivitis with ibuprofen or flurbiprofen Download PDF

Info

Publication number
WO1988003021A3
WO1988003021A3 PCT/US1987/002587 US8702587W WO8803021A3 WO 1988003021 A3 WO1988003021 A3 WO 1988003021A3 US 8702587 W US8702587 W US 8702587W WO 8803021 A3 WO8803021 A3 WO 8803021A3
Authority
WO
WIPO (PCT)
Prior art keywords
flurbiprofen
ibuprofen
gingivitis
treatment
pharmaceutically acceptable
Prior art date
Application number
PCT/US1987/002587
Other languages
French (fr)
Other versions
WO1988003021A2 (en
Inventor
Charles M Hall
Herbert G Johnson
Steven Offenbacher
Original Assignee
Upjohn Co
Charles M Hall
Herbert G Johnson
Steven Offenbacher
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co, Charles M Hall, Herbert G Johnson, Steven Offenbacher filed Critical Upjohn Co
Publication of WO1988003021A2 publication Critical patent/WO1988003021A2/en
Priority to KR1019880700708A priority Critical patent/KR880701547A/en
Publication of WO1988003021A3 publication Critical patent/WO1988003021A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Method of treating gingivitis using ibuprofen of flurbiprofen or a pharmaceutically acceptable salt or a C1 to C6 alkyl ester thereof.
PCT/US1987/002587 1986-10-22 1987-10-13 Treatment of gingivitis with ibuprofen or flurbiprofen WO1988003021A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1019880700708A KR880701547A (en) 1986-10-22 1988-06-21 Treatment of gingivitis with ibuprofen or flurbiprofen

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US92199086A 1986-10-22 1986-10-22
US921,990 1986-10-22

Publications (2)

Publication Number Publication Date
WO1988003021A2 WO1988003021A2 (en) 1988-05-05
WO1988003021A3 true WO1988003021A3 (en) 1988-06-30

Family

ID=25446307

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1987/002587 WO1988003021A2 (en) 1986-10-22 1987-10-13 Treatment of gingivitis with ibuprofen or flurbiprofen

Country Status (5)

Country Link
EP (1) EP0321505A1 (en)
JP (1) JPH02500189A (en)
KR (1) KR880701547A (en)
AU (1) AU8320387A (en)
WO (1) WO1988003021A2 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH02196717A (en) * 1988-10-07 1990-08-03 Block Drug Co Inc Periodontitis therapy
CA2064722C (en) * 1989-08-17 2001-05-08 William J. Wechter Buccal composition containing s(+) flurbiprofen or ketoprofen
US5190981A (en) * 1989-08-17 1993-03-02 Sepracor Inc. Formulation containing S(+) enantiomer of flurbiprofen or ketoprofen and method of use for oral administration for prevention and treatment of bone loss associated with periodontal disease
GB9523833D0 (en) * 1995-11-22 1996-01-24 Boots Co Plc Medical treatment
US8865198B2 (en) 2010-10-25 2014-10-21 Dexcel Pharma Technologies Ltd. Method for treating a periodontal disease
WO2017029710A1 (en) * 2015-08-18 2017-02-23 合同会社Ｐｈａｒｍａ Ｓｅｅｄｓ Ｃｒｅａｔｅ Oral composition containing nsaid or heparin compound

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0137668B1 (en) * 1983-08-31 1990-01-17 The Upjohn Company Ibuprofen, flurbiprofen and their therapeutic use

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0137668B1 (en) * 1983-08-31 1990-01-17 The Upjohn Company Ibuprofen, flurbiprofen and their therapeutic use

Also Published As

Publication number Publication date
WO1988003021A2 (en) 1988-05-05
JPH02500189A (en) 1990-01-25
AU8320387A (en) 1988-05-25
KR880701547A (en) 1988-11-03
EP0321505A1 (en) 1989-06-28

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