WO1987005779A1 - Procede prophylactique et composition utilisee - Google Patents

Procede prophylactique et composition utilisee Download PDF

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Publication number
WO1987005779A1
WO1987005779A1 PCT/US1987/000634 US8700634W WO8705779A1 WO 1987005779 A1 WO1987005779 A1 WO 1987005779A1 US 8700634 W US8700634 W US 8700634W WO 8705779 A1 WO8705779 A1 WO 8705779A1
Authority
WO
WIPO (PCT)
Prior art keywords
person
toilet seat
aerosol composition
lower alkanol
germ
Prior art date
Application number
PCT/US1987/000634
Other languages
English (en)
Inventor
Jonah Shacknai
Original Assignee
Jonah Shacknai
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jonah Shacknai filed Critical Jonah Shacknai
Publication of WO1987005779A1 publication Critical patent/WO1987005779A1/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/16—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using chemical substances
    • A61L2/22—Phase substances, e.g. smokes, aerosols or sprayed or atomised substances
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/02—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing liquids as carriers, diluents or solvents
    • A01N25/04—Dispersions, emulsions, suspoemulsions, suspension concentrates or gels
    • A01N25/06—Aerosols
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
    • A01N47/40—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having a double or triple bond to nitrogen, e.g. cyanates, cyanamides
    • A01N47/42—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having a double or triple bond to nitrogen, e.g. cyanates, cyanamides containing —N=CX2 groups, e.g. isothiourea
    • A01N47/44—Guanidine; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Definitions

  • This invention relates to the field of medicine and more specifically to a method and composition for prevention of disease encountered in public washroom facilities.
  • Disinfectants have been known for many years, with a primary object of household sanitation in modern society being to keep restroom surfaces, and particularly those associated with the toilet, free from germs that can cause infection of a person coming into skin contact, typically when seated on a toilet.
  • hexamethylenebisbiguanide compound known as Chlorhexidine gluconate. which is typically administered to a surface in a four percent solution in a mild, sudsing base which is adjusted to a pH of from about 5.0 to about 6.5, and used in that form to treat skin.
  • Patent 4,364,515 granted December 21, 1982, teaches a water-in-air emulsion or suspension as an improvement in aerosol compositions which are stated as generally used for bath and body powders, make-up powders, foot powders, personal deodorant and antiperspirant powders, and a variety of other uses. (column 2, lines 18-18). Prussin teaches the use of hydrophobic metal oxides, particularly silane treated silicas (column 2, lines 28-0).
  • Schleppnik U.S. Patent 4,310,512, granted December 4, 1979, discloses treatment of offensive odors with a combination of a perfume and fragrances.
  • an object of the present invention is to provide a method of keeping a toilet surface germ-free.
  • an airport washroom facility is used numerous times by all types of persons over the course of a day and between cleaning by airport personnel. It is highly desirable to provide the traveller with a convenient means of sanitizing washroom surfaces in such public facilities, without the need to carry cleaning fluids, cloths, and other items necessary to provide safety from infection.
  • a toilet seat cleansing unit which comprises a pressurized container housing a toilet seat aerosol composition capable of being ejected at a distance of from about six inches to two feet from said pressurized container, said aerosol composition being suitable for prophylaxis against infections of persons coming into time direct physical contact with said toilet seat, said aerosol composition comprising an aqueous lower alkanol solution with up to about 4.0 percent by weight of Chlorhexidine gluconate, whereby upon administration of said aerosol composition to said toilet seat there are rendered ineffective germs capable of otherwise topically infecting the person at the point of bodily contact with said toilet seat.
  • the lower alkanol is isopropyl alcohol.
  • said lower alkanol is ethanol.
  • a mixture of about one part isopropyl alcohol and one part ethanol forms yet a further aspect of the invention.
  • said Chlorhexidine gluconate is present in an amount of about 0.1 to 3.0 percent by weight of said lower alkanol.
  • a method of prevention of infection of a person through direct skin contact of said person to a germ-containing surface in a washroom facility which comprises applying a coating of an aerosol composition over said germ-containing surface at the point of expected skin contact therewith, said aerosol composition being suitable for prophylaxis against infections of persons coming into time direct physical contact with said germ-containing surface, said aerosol composition comprising an aqueous lower alkanol solution with up to about 4.0 percent by weight of Chlorhexidine gluconate, whereby upon administration of said aerosol composition to said germ-containing surface there are rendered ineffective germs capable of otherwise topically infecting the person at the point of bodily contact with said germ-containing surface.
  • a method of prevention of infection of a person through direct skin contact of said person to a toilet seat which comprises applying a coating of an aerosol composition over said toilet seat at the point of expected skin contact therewith, said aerosol composition being suitable for prophylaxis against infections of persons coming into time direct physical contact with said toilet seat, said aerosol composition comprising an aqueous lower alkanol solution with up to about 4.0 percent by weight of Chlorhexidine gluconate, whereby upon administration of said aerosol composition to said toilet seat there are rendered ineffective germs capable of otherwise topically infecting the person at the point of bodily contact with said toilet seat.
  • a purse- or pocket-sized cleansing unit which contains a pressurized toilet seat aerosol composition capable of being ejected at a distance of from about six inches to two feet from said pressurized container, said aerosol composition being suitable for prophylaxis against infections of persons coming into time direct physical contact with said toilet seat, said aerosol composition containing a disinfectant, whereby upon administration of said aerosol composition to said toilet seat there are rendered ineffective germs capable of otherwise topically infecting the person at the point of bodily contact with said toilet seat.
  • An aerosol composition is prepared with a 4 percent Chlorhexidine gluconate in an ethanol solution, together with conventional aerosol spray adjuvants, to provide a spray to be administered to a toilet seat from a distance of about eight to ten inches. A brief spray of this aerosol composition instantly kills the usual bathroom germs that are found on toilet seats.
  • An aerosol composition is prepared with a 3 percent Chlorhexidine gluconate in an alkanol mixture of one half isopropyl alcohol and one half ethanol solution, together with conventional aerosol spray adjuvants, to provide a spray to be administered to a toilet seat from a distance of about eight to ten inches.
  • a brief spray of this aerosol composition instantly kills the usual bathroom germs that are found on toilet seats.
  • EXAMPLE III An aerosol composition is prepared with a 2 percent Chlorhexidine gluconate in an ethanol solution, together with conventional aerosol spray adjuvants, to provide a spray to be administered to a toilet seat from a distance of about eight to ten inches. A brief spray of this aerosol composition instantly kills the usual bathroom germs that are found on toilet seats.
  • EXAMPLE IV An aerosol composition is prepared with a 2 percent Chlorhexidine gluconate in an ethanol solution, together with conventional aerosol spray adjuvants, to provide a spray to be administered to a toilet seat from a distance of about eight to ten inches. A brief spray of this aerosol composition instantly kills the usual bathroom germs that are found on toilet seats.
  • An aerosol composition is prepared with a 4 percent Chlorhexidine gluconate in an isopropanol solution, together with conventional aerosol spray adjuvants, to provide a spray to be administered to a toilet seat from a distance of about eight to ten inches. A brief spray of this aerosol composition instantly kills the usual bathroom germs that are found on toilet seats.
  • EXAMPLE V An aerosol composition is prepared with a 1 percent Chlorhexidine gluconate in an ethanol solution, together with conventional aerosol spray adjuvants, to provide a spray to be administered to a toilet seat from a distance of about eight to ten inches. A brief spray of this aerosol composition instantly kills the usual bathroom germs that are found on toilet seats.
  • EXAMPLE VI An aerosol composition of Example 1 is useful for killing germs on surfaces where they proliferate. Such an aerosol composition is sprayed onto a surface contaminated with Staphylococcus aureus. The composition kills the germ and, thus, provides a surface free from the germ such that bodily contact with the surface is undertaken without fear of germicidal contamination.
  • EXAMPLE VII An aerosol composition of Example 1 is useful for killing germs on surfaces where they proliferate. Such an aerosol composition is sprayed onto a surface contaminated with Staphylococcus aureus. The composition kills the germ and, thus, provides a surface free from the germ such that bodily contact with the surface is undertaken without fear of germicidal contamination.
  • An aerosol composition of Example 2 is useful for killing germs on surfaces where they proliferate. Such an aerosol composition is sprayed onto a surface contaminated with Pseudomonas aeruginosa. The composition kills the germ and, thus, provides a surface free from the germ such that bodily contact with the surface is undertaken without fear of germicidal contamination.
  • EXAMPLE VIII An aerosol composition of Example 3 is useful for killing germs on surfaces where they proliferate. Such an aerosol composition is sprayed onto a surface contaminated with
  • Salmonella choleraesuis The composition kills the germ and, thus, provides a surface free from the germ such that bodily contact with the surface is undertaken without fear of germicidal contamination.
  • Example 4 An aerosol composition of Example 4 is useful for killing viruses on surfaces where they proliferate. Such an aerosol composition is sprayed onto a surface contaminated with Herpes simplex virus type I. The composition kills the virus and, thus, provides a surface free from the virus such that bodily contact with the surface is undertaken without fear of virucidal contamination.
  • EXAMPLE X EXAMPLE X
  • An aerosol composition of Example 5 is useful for killing viruses on surfaces where they proliferate. Such an aerosol composition is sprayed onto a surface contaminated with Herpes simplex virus type II. The composition kills the virus and, thus, provides a surface free from the virus such that bodily contact with the surface is undertaken without fear of virucidal contamination.

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Pest Control & Pesticides (AREA)
  • Dentistry (AREA)
  • Plant Pathology (AREA)
  • Dispersion Chemistry (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Agronomy & Crop Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Toxicology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Unité de nettoyage de siège de toilettes comprenant un récipient sous pression contenant une composition aérosol pour siège de toilettes pouvant être éjectée à une distance allant de 6 pouces à 2 pieds du récipient sous pression. La composition aérosol utilisée convient à la prophylaxie contre les infections de personnes entrant en contact physique direct avec le siège de toilettes. Une telle composition aérosol comprend une solution aqueuse d'alkanol inférieur contenant jusqu'à environ 4,0% en poids de gluconate de chlorhexidine. L'application de la composition aérosol sur le siège de toilettes rend inactifs les germes responsables d'éventuelles infections topiques de l'utilisateur du siège au point de contact avec ce dernier.
PCT/US1987/000634 1986-03-28 1987-03-26 Procede prophylactique et composition utilisee WO1987005779A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US84525186A 1986-03-28 1986-03-28
US845,251 1986-03-28

Publications (1)

Publication Number Publication Date
WO1987005779A1 true WO1987005779A1 (fr) 1987-10-08

Family

ID=25294773

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1987/000634 WO1987005779A1 (fr) 1986-03-28 1987-03-26 Procede prophylactique et composition utilisee

Country Status (2)

Country Link
JP (1) JPH01502113A (fr)
WO (1) WO1987005779A1 (fr)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0257824A2 (fr) * 1986-08-06 1988-03-02 Kobayashi Pharmaceutical Co. Ltd. Papier et vaporisateur de liquide pour nettoyer un siège de toilette
WO2006082393A1 (fr) * 2005-02-01 2006-08-10 Sinclair Pharmaceuticals Limited Emploi de dérivés de morpholine dans la prévention d'une contamination bactérienne
US8603393B1 (en) * 2009-12-01 2013-12-10 Albert Charles DolceAmore Oral sanitary system for sports

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU254337A (en) * 1937-06-21 1938-07-07 McKenzie and Holland Australia Proprietary Limited Improvements relating to signal apparatus of the search light type
BE893125A (fr) * 1982-05-07 1982-08-30 Gilliard Christian Preparation desinfectante et nettoyante pour lunettes de w.c.
EP0099209A1 (fr) * 1982-07-01 1984-01-25 JOHNSON & JOHNSON MEDICAL, INC. Solutions aqueuses de désinfectant possédant une activité biocide résiduelle
EP0132038A1 (fr) * 1983-06-09 1985-01-23 Rizla Limited Germicides sous forme d'aérosols

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU254337A (en) * 1937-06-21 1938-07-07 McKenzie and Holland Australia Proprietary Limited Improvements relating to signal apparatus of the search light type
BE893125A (fr) * 1982-05-07 1982-08-30 Gilliard Christian Preparation desinfectante et nettoyante pour lunettes de w.c.
EP0099209A1 (fr) * 1982-07-01 1984-01-25 JOHNSON & JOHNSON MEDICAL, INC. Solutions aqueuses de désinfectant possédant une activité biocide résiduelle
EP0132038A1 (fr) * 1983-06-09 1985-01-23 Rizla Limited Germicides sous forme d'aérosols

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0257824A2 (fr) * 1986-08-06 1988-03-02 Kobayashi Pharmaceutical Co. Ltd. Papier et vaporisateur de liquide pour nettoyer un siège de toilette
EP0257824A3 (fr) * 1986-08-06 1988-12-14 Kobayashi Pharmaceutical Co. Ltd. Papier et vaporisateur de liquide pour nettoyer un siège de toilette
WO2006082393A1 (fr) * 2005-02-01 2006-08-10 Sinclair Pharmaceuticals Limited Emploi de dérivés de morpholine dans la prévention d'une contamination bactérienne
US8999365B2 (en) 2005-02-01 2015-04-07 Sinclair Pharmaceuticals Limited Prevention of bacterial contamination
US8603393B1 (en) * 2009-12-01 2013-12-10 Albert Charles DolceAmore Oral sanitary system for sports

Also Published As

Publication number Publication date
JPH01502113A (ja) 1989-07-27

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