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Publication of UY39738ApublicationCriticalpatent/UY39738A/en
La invención se refiere a compuestos de la Fórmula I” donde R, R1, R2, R3, p, q y q’ son como se definen en el presente documento, composiciones farmacéuticas que comprenden los compuestos, métodos para tratar la infección por coronavirus como la COVID-19 en un paciente mediante la administración de cantidades terapéuticamente eficaces de los compuestos, y métodos de inhibir o prevenir la replicación del coronavirus tal como el SARS-CoV-2 con los compuestosThe invention relates to compounds of Formula I" where R, R1, R2, R3, p, q and q' are as defined herein, pharmaceutical compositions comprising the compounds, methods of treating coronavirus infection such as COVID-19 in a patient by administering therapeutically effective amounts of the compounds, and methods of inhibiting or preventing the replication of coronaviruses such as SARS-CoV-2 with the compounds