UY39506A - Composiciones de fagos para pseudomonas que comprenden sistemas crispr-cas y métodos de uso de estas - Google Patents

Composiciones de fagos para pseudomonas que comprenden sistemas crispr-cas y métodos de uso de estas

Info

Publication number
UY39506A
UY39506A UY0001039506A UY39506A UY39506A UY 39506 A UY39506 A UY 39506A UY 0001039506 A UY0001039506 A UY 0001039506A UY 39506 A UY39506 A UY 39506A UY 39506 A UY39506 A UY 39506A
Authority
UY
Uruguay
Prior art keywords
crispr
methods
pseudomonas
phages
compositions
Prior art date
Application number
UY0001039506A
Other languages
English (en)
Spanish (es)
Inventor
M Garofolo Paul
G Ousterout David
Kurt Selle
Hewitt Tuson Hannah
Lana Mcmillan
Robert Mckee
Taylor Penke
Shaun Steele
Christopher Ladner
Al-Ghalith Gabriel
Original Assignee
Janssen Res & Development Llc
Locus Biosciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Res & Development Llc, Locus Biosciences Inc filed Critical Janssen Res & Development Llc
Publication of UY39506A publication Critical patent/UY39506A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N63/00—Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
    • A01N63/40—Viruses, e.g. bacteriophages
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/102—Mutagenizing nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/20—Type of nucleic acid involving clustered regularly interspaced short palindromic repeats [CRISPR]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2795/00—Bacteriophages
    • C12N2795/00011—Details
    • C12N2795/10011—Details dsDNA Bacteriophages
    • C12N2795/10041—Use of virus, viral particle or viral elements as a vector
    • C12N2795/10043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Virology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Dentistry (AREA)
  • Environmental Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
UY0001039506A 2020-11-05 2021-11-05 Composiciones de fagos para pseudomonas que comprenden sistemas crispr-cas y métodos de uso de estas UY39506A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202063110288P 2020-11-05 2020-11-05
US202163184728P 2021-05-05 2021-05-05

Publications (1)

Publication Number Publication Date
UY39506A true UY39506A (es) 2022-05-31

Family

ID=81458404

Family Applications (1)

Application Number Title Priority Date Filing Date
UY0001039506A UY39506A (es) 2020-11-05 2021-11-05 Composiciones de fagos para pseudomonas que comprenden sistemas crispr-cas y métodos de uso de estas

Country Status (8)

Country Link
US (1) US20240011041A1 (enExample)
EP (1) EP4240165A4 (enExample)
JP (1) JP2023548581A (enExample)
AU (1) AU2021373795A1 (enExample)
CA (1) CA3197191A1 (enExample)
TW (1) TW202233832A (enExample)
UY (1) UY39506A (enExample)
WO (1) WO2022098916A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115960895B (zh) * 2022-08-09 2026-04-10 中国科学院微生物研究所 一种偶联的crispr和毒素-抗毒素元件及其在消杀耐药细菌中的应用
EP4712993A2 (en) * 2023-05-17 2026-03-25 The Regents of the University of California Phage therapy for alcohol-associated hepatitis
WO2025076308A1 (en) * 2023-10-06 2025-04-10 University Of Florida Research Foundation, Incorporated Compositions and methods for analyzing the effect of microbiota on host protein conformation and treating neurodegenerative diseases
CN117959655B (zh) * 2024-01-31 2026-06-23 四川大学 一种假单胞菌还原剂及其在钒还原中的应用和方法
WO2025206239A1 (ja) * 2024-03-28 2025-10-02 国立感染症研究所長が代表する日本国 組換えファージ及び遺伝子のスクリーニング方法
WO2026150377A1 (en) 2025-01-13 2026-07-16 Locus Biosciences, Inc. Bacteriophage compositions and uses for treatment of escherichia coli (e. coli) colonization

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107208070B (zh) * 2014-11-26 2021-09-07 技术创新动力基金(以色列)有限合伙公司 细菌基因的靶向消除
AU2016280002B2 (en) * 2015-06-15 2022-04-14 North Carolina State University Methods and compositions for efficient delivery of nucleic acids and RNA-based antimicrobials
US9896696B2 (en) * 2016-02-15 2018-02-20 Benson Hill Biosystems, Inc. Compositions and methods for modifying genomes
GB201710126D0 (en) * 2017-06-25 2017-08-09 Snipr Tech Ltd Vectors & Methods
US20230193241A1 (en) * 2017-06-25 2023-06-22 Snipr Technologies Limited Altering microbial populations & modifying microbiota
US20190160120A1 (en) * 2017-11-29 2019-05-30 Snipr Biome Aps Dna, methods etc
KR20210018273A (ko) * 2018-05-04 2021-02-17 로커스 바이오사이언스, 인크. 표적 박테리아를 사멸시키기 위한 방법 및 조성물
WO2019227080A1 (en) * 2018-05-25 2019-11-28 Locus Biosciences, Inc. Methods and compositions for killing a target bacterium
US20220370526A1 (en) * 2019-11-06 2022-11-24 Locus Biosciences, Inc. Phage compositions comprising crispr-cas systems and methods of use thereof

Also Published As

Publication number Publication date
CA3197191A1 (en) 2022-05-12
US20240011041A1 (en) 2024-01-11
JP2023548581A (ja) 2023-11-17
EP4240165A1 (en) 2023-09-13
TW202233832A (zh) 2022-09-01
AU2021373795A1 (en) 2023-06-22
EP4240165A4 (en) 2025-04-02
WO2022098916A1 (en) 2022-05-12
AU2021373795A9 (en) 2024-10-03

Similar Documents

Publication Publication Date Title
CL2021003373A1 (es) Nuevos inhibidores de egfr
BR112021024224A2 (pt) Inibidores de tead e usos dos mesmos
MX2021014443A (es) Inhibidores del dominio asociado mejorador de la transcripcion (tead) y usos de los mismos.
UY39135A (es) ANTICUERPOS MONOCLONALES HUMANOS DIRIGIDOS CONTRAEL CORONAVIRUS 2 DEL SÍNDROME RESPIRATORIO AGUDO GRAVE (SARS-CoV-2)
MX2022007576A (es) Degradadores de cinasas asociadas al receptor de interleucina-1 (irak) y usos de los mismos.
MX2022007527A (es) Inhibidores de proteinas kras mutantes.
CL2021001690S1 (es) Estuche para audífonos.
CO2022008662A2 (es) Degradadores de smarca y usos de los mismos
CO2018013557A2 (es) Composiciones que comprenden cepas bacterianas
CL2020000075A1 (es) Carboxamidas como moduladores de los canales de sodio.
MX2021013225A (es) Composiciones y metodos para el tratamiento del cancer utilizando una terapia de celulas t modificadas de cd8.
BR112018070133A2 (pt) dispersão, uso desta e método para a inativação fotodinâmica de micro-organismos
CL2021001175S1 (es) Estuche para audífonos.
CU20190092A7 (es) Antimitoscinas: inhibidores específicos de la biogénesis mitocondrial para erradicar células madre cancerosas
CL2020002052A1 (es) Composiciones de edb que se dirigen a il-12.
CL2023002198A1 (es) Compuestos antiparasitarios.
CL2021001461A1 (es) Moduladores de trex1
CL2023003694A1 (es) Anticuerpos anti-pcrv que se unen a pcrv, composiciones que comprenden anticuerpos anti-pcrv, métodos de uso
AR114780A1 (es) Formulaciones estables de inmunoconjugado anti-cd79b
MX2020004179A (es) Combinacion que comprende al menos un modulador de espliceosomas y al menos un inhibidor elegido de inhibidores de bcl2, bcl2/bclxl y bclxl, y metodos de uso.
CO2019002751A2 (es) Composiciones marcadoras, y metodos para fabricar y usar las mismas
CL2022000807A1 (es) Compuesto bicíclico y uso del mismo
MX2022003001A (es) Metodos para tratar el cancer mediante el uso de inhibidores del eje de pd-1 y anticuerpos anti-periostina.
CO2025016192A2 (es) Moléculas y métodos de uso de estas
CL2021002501A1 (es) Compuestos novedosos y métodos de uso de los mismos.

Legal Events

Date Code Title Description
109 Application deemed to be withdrawn

Effective date: 20260415