UY36948A - Formulaciones de corticosteroides para mantener concentraciones de corticosteroide en el líquido sinovial - Google Patents
Formulaciones de corticosteroides para mantener concentraciones de corticosteroide en el líquido sinovialInfo
- Publication number
- UY36948A UY36948A UY0001036948A UY36948A UY36948A UY 36948 A UY36948 A UY 36948A UY 0001036948 A UY0001036948 A UY 0001036948A UY 36948 A UY36948 A UY 36948A UY 36948 A UY36948 A UY 36948A
- Authority
- UY
- Uruguay
- Prior art keywords
- corticosteroid
- formulations
- analgesic effect
- maintain
- release
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
- A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Rheumatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Physical Education & Sports Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Preparation (AREA)
Abstract
La invención refiere a composiciones y métodos para obtener y mantener un máximo efecto analgésico luego de administración intra-articular de formulaciones de corticosteroides. También describe formulaciones de liberación extendida, por ejemplo, formulaciones de corticosteroides de liberación controlada o sostenida, incluyendo formulaciones de liberación extendida, por ejemplo, formulaciones de liberación controlada o sostenida de acetonida de triamcinolona (TCA), propionato de fluticasona, cortisol, ciclesonida (monopropionato), dipropionato de beclometasona, dexametasona, flunisolida, budesonida, desisobutiril-ciclesonida, y/o furoato de mometasona, que producen máximo efecto analgésico mayor al efecto analgésico agudo proporcionado por suspensiones de corticosteroides estándar, y que también se asocian con efecto clínicamente insignificante sobre producción de cortisol endógeno luego de administración.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201562240811P | 2015-10-13 | 2015-10-13 |
Publications (1)
Publication Number | Publication Date |
---|---|
UY36948A true UY36948A (es) | 2017-05-31 |
Family
ID=58498560
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
UY0001036948A UY36948A (es) | 2015-10-13 | 2016-10-13 | Formulaciones de corticosteroides para mantener concentraciones de corticosteroide en el líquido sinovial |
Country Status (5)
Country | Link |
---|---|
US (1) | US20170100411A1 (es) |
AR (1) | AR106330A1 (es) |
TW (1) | TW201726145A (es) |
UY (1) | UY36948A (es) |
WO (1) | WO2017066423A1 (es) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TWI843284B (zh) * | 2021-11-11 | 2024-05-21 | 中央研究院 | 診斷及治療骨關節炎的方法 |
US11896719B2 (en) | 2022-01-24 | 2024-02-13 | Calliditas Therapeutics Ab | Pharmaceutical compositions |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
UA111162C2 (uk) * | 2010-08-04 | 2016-04-11 | Флекшен Терап'Ютікс, Інк. | Ін'єкційна композиція ацетоніду триамцинолону для лікування болю |
WO2014153384A1 (en) * | 2013-03-19 | 2014-09-25 | Flexion Therapeutics, Inc. | Corticosteroid formulations for the treatment of joint pain and methods of use thereof |
BR112015024234B1 (pt) * | 2013-03-21 | 2022-11-16 | Eupraxia Pharmaceuticals USA LLC | Composição farmacêutica de liberação sustentada injetável, uso da mesma para diminuir inflamação ou controlar dor e método para formar micropartículas revestidas |
-
2016
- 2016-10-13 UY UY0001036948A patent/UY36948A/es not_active Application Discontinuation
- 2016-10-13 AR ARP160103120A patent/AR106330A1/es unknown
- 2016-10-13 TW TW105133081A patent/TW201726145A/zh unknown
- 2016-10-13 US US15/292,670 patent/US20170100411A1/en not_active Abandoned
- 2016-10-13 WO PCT/US2016/056803 patent/WO2017066423A1/en active Application Filing
Also Published As
Publication number | Publication date |
---|---|
TW201726145A (zh) | 2017-08-01 |
AR106330A1 (es) | 2018-01-03 |
WO2017066423A1 (en) | 2017-04-20 |
US20170100411A1 (en) | 2017-04-13 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
109 | Application deemed to be withdrawn |
Effective date: 20221129 |