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Application filed by Alphora Res IncfiledCriticalAlphora Res Inc
Priority to UY0001035627ApriorityCriticalpatent/UY35627A/en
Publication of UY35627ApublicationCriticalpatent/UY35627A/en
Se describe un compuesto de fórmula 1, como se muestra a continuación, donde R1, R2, R3, R4, R5, R6 y R7 son como se describen en la presente. También es descripto un procedimiento para la preparación de compuestos de fórmula 1, y los intermediarios utilizados en el mismo. El compuesto de fórmula 1 puede ser útil para la preparación de análogos de halicondrina tal como la Eribulina.A compound of formula 1 is described, as shown below, where R1, R2, R3, R4, R5, R6 and R7 are as described herein. A process for the preparation of compounds of formula 1, and the intermediates used therein, is also described. The compound of formula 1 may be useful for the preparation of halicondrine analogs such as Eribulin.
UY0001035627A2014-06-252014-06-25
DERIVATIVES OF 2 - ((2S, 3S, 4R, 5R) -5 - ((S) -3-AMINO-2-HIDROXIPROP-1-IL) -4-METOXI-3- (PHENYLSULPHONYLMETIL) TETRAHYDROFURAN-2-IL) ACETALDEHYDE AND PROCEDURE FOR PREPARATION.
UY35627A
(en)
Processes for making 2 - ((3r, 5r, 6s) -5- (3-chlorophenyl) -6- (4-chlorophenyl) -1 - ((s) -1- (isopropylsulfonyl) -3-methylbutan-2- acid yl) -3-methyl-2-oxopiperidin-3-yl) acetic, intermediates and processes for making the intermediates, crystalline forms of the compound and the intermediates. (divisional application no. 2015003589)