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Medicines Containing Material From Animals Or Micro-Organisms
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(AREA)
Abstract
Se describen proteínas de enlace a antígenos aisladas, tales como pero no limitadas a, un anticuerpo o fragmento de anticuerpos, que enlaza específicamente a SEQ ID NO:4, la secuencia de aminoacidos del rizo extracelular 2 (ECL2) de Orai 1 humano. También se describen composiciones farmacéuticas y medicamentos que comprenden la proteína de enlace a antígenos, ácido nucléico aislado que la codifica, vectores y células hospederas útiles en métodos de su elaboración, y métodos de uso en el tratamiento de trastornos o enfermedades en pacientes.Isolated antigen binding proteins are described, such as but not limited to, an antibody or antibody fragment, which specifically binds SEQ ID NO: 4, the amino acid sequence of the extracellular curl 2 (ECL2) of human Orai 1. Also described are pharmaceutical compositions and medicaments comprising the antigen binding protein, isolated nucleic acid encoding it, vectors and host cells useful in methods of its elaboration, and methods of use in the treatment of disorders or diseases in patients.
UY33043A2010-10-222010-11-19
ANTI-ORAI 1 ANTIGEN LINK PROTEINS AND USES OF THE SAME
UY33043A
(en)
Antibody that binds to human or cynomolgus complement protein c3b; pharmaceutical composition, nucleic acid, vector and host cell comprising said antibody; use to treat age-related macular degeneration.
Immunogenic peptides for use in the prevention and/or treatment of infectious diseases, autoimmune diseases, immune responses to allofactors, allergic diseases, tumors, graft rejection and immune responses against viral vectors used for gene therapy or gene vaccination