UY32294A - TETRAHIDROPIRAN ESPIRO PIRROLIDINONA AND PIPERIDINONA SUBSTITUTED, ITS PREPARATION AND THERAPEUTIC USE - Google Patents

TETRAHIDROPIRAN ESPIRO PIRROLIDINONA AND PIPERIDINONA SUBSTITUTED, ITS PREPARATION AND THERAPEUTIC USE

Info

Publication number
UY32294A
UY32294A UY0001032294A UY32294A UY32294A UY 32294 A UY32294 A UY 32294A UY 0001032294 A UY0001032294 A UY 0001032294A UY 32294 A UY32294 A UY 32294A UY 32294 A UY32294 A UY 32294A
Authority
UY
Uruguay
Prior art keywords
substituted
preparation
tetrahidropiran
pirrolidinona
piperidinona
Prior art date
Application number
UY0001032294A
Other languages
Spanish (es)
Inventor
Gao Zhongli
Stefany David
Ryan E Hartung
Original Assignee
Sanofi Aventis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis filed Critical Sanofi Aventis
Publication of UY32294A publication Critical patent/UY32294A/en

Links

Classifications

    • G—PHYSICS
    • G05—CONTROLLING; REGULATING
    • G05G—CONTROL DEVICES OR SYSTEMS INSOFAR AS CHARACTERISED BY MECHANICAL FEATURES ONLY
    • G05G1/00—Controlling members, e.g. knobs or handles; Assemblies or arrangements thereof; Indicating position of controlling members
    • G05G1/30—Controlling members actuated by foot
    • G05G1/46—Means, e.g. links, for connecting the pedal to the controlled unit
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • G—PHYSICS
    • G05—CONTROLLING; REGULATING
    • G05G—CONTROL DEVICES OR SYSTEMS INSOFAR AS CHARACTERISED BY MECHANICAL FEATURES ONLY
    • G05G23/00—Means for ensuring the correct positioning of parts of control mechanisms, e.g. for taking-up play
    • G05G23/02—Means for ensuring the correct positioning of parts of control mechanisms, e.g. for taking-up play self-adjusting

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Psychiatry (AREA)
  • Physics & Mathematics (AREA)
  • Automation & Control Theory (AREA)
  • General Physics & Mathematics (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Psychology (AREA)
  • Hematology (AREA)
  • Hospice & Palliative Care (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Mechanical Control Devices (AREA)

Abstract

Se describe y reivindica una serle de carboxamidas N-fenil-bipirridina sustituidas de formula (I). Donde R1, R2, m, n y p son como se definió anteriormente en este documento. Los compuestos de esta invención son moduladores de los receptores H3 y, por lo tanto, son útiles como agentes farmacéuticos, especialmente en el tratamiento y/o prevención de una variedad de enfermedades moduladas por los receptores H3, incluyendo enfermedades asociadas con el sistema nervioso central. Además, la presente invención también describe métodos para la preparación de carboxamidas N-fenil-bipirrolidina sustituidas e intermedios para ello.A series of substituted N-phenyl-bipyrridine carboxamides of formula (I) is described and claimed. Where R1, R2, m, n and p are as defined earlier in this document. The compounds of this invention are modulators of the H3 receptors and, therefore, are useful as pharmaceutical agents, especially in the treatment and / or prevention of a variety of diseases modulated by the H3 receptors, including diseases associated with the central nervous system. . In addition, the present invention also describes methods for the preparation of substituted and intermediate N-phenyl-bipyrrolidine carboxamides therefor.

UY0001032294A 2008-12-05 2009-12-04 TETRAHIDROPIRAN ESPIRO PIRROLIDINONA AND PIPERIDINONA SUBSTITUTED, ITS PREPARATION AND THERAPEUTIC USE UY32294A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12008708P 2008-12-05 2008-12-05
FR0955908A FR2949580A1 (en) 2009-08-28 2009-08-28 Vehicle i.e. motor vehicle, has return unit connected with pedal, another return unit for ensuring continuous tensioning of cable, and drive part pivotally mounted with axis of rotation of pedal

Publications (1)

Publication Number Publication Date
UY32294A true UY32294A (en) 2010-07-30

Family

ID=41665144

Family Applications (1)

Application Number Title Priority Date Filing Date
UY0001032294A UY32294A (en) 2008-12-05 2009-12-04 TETRAHIDROPIRAN ESPIRO PIRROLIDINONA AND PIPERIDINONA SUBSTITUTED, ITS PREPARATION AND THERAPEUTIC USE

Country Status (2)

Country Link
FR (1) FR2949580A1 (en)
UY (1) UY32294A (en)

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1411467A (en) * 1973-10-27 1975-10-22 Ford Motor Co Self-adjusting clutch mechanism
IT1031957B (en) * 1975-02-21 1979-05-10 Ind Napoletana Costpuzione Aut ACCELERATOR PEDAL FOR MOTOR VEHICLES
US4227603A (en) * 1978-11-15 1980-10-14 Start S.P.A. Studi Apparecchiature E Ricerche Tecniche Device for automatic compensation of wear in friction drive clutches of motor vehicles
US4263999A (en) * 1978-12-21 1981-04-28 Start S.P.A. Studi Apparecchiature E Ricerche Devices for the automatic elimination of play in motor vehicle clutches
US4381053A (en) * 1979-10-26 1983-04-26 Toyota Jidosha Kogyo Kabushiki Kaisha Cable-type clutch release device for usually contacting-type clutch
FR2492923B1 (en) * 1980-10-29 1986-03-14 Renault COMPENSATION DEVICE FOR THE WEAR OF A VEHICLE CLUTCH
US4850242A (en) * 1988-07-19 1989-07-25 Orscheln Co. Soft-release cable operating means
FR2751441B1 (en) * 1996-07-16 1998-10-09 Peugeot CONTROL DEVICE AND APPLICATION OF THIS DEVICE TO THE ACCELERATOR CONTROL OF A MOTOR VEHICLE

Also Published As

Publication number Publication date
FR2949580A1 (en) 2011-03-04

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Legal Events

Date Code Title Description
109 Application deemed to be withdrawn

Effective date: 20181219