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Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Abstract
Se proporcionan compuestos de la Formula I en donde R2, R3, R13, L y D2 son lo definidos en la memoria descriptiva, que son utiles en el tratamiento y/o en la prevencion de enfermedades o trastornos mediados por niveles deficientes de actividad de glucocinasa o que se pueden tratar activando glucocinasa que incluyen, en forma no taxativa, diabetes mellitus, deterioro de tolerancia de la glucosa, IFG (deterioro de glicemia en ayunas), asà como otras enfermedades y trastornos tales como aquellos discutidos en la presente.Compounds of Formula I are provided wherein R2, R3, R13, L and D2 are as defined in the specification, which are useful in the treatment and / or in the prevention of diseases or disorders mediated by deficient levels of glucokinase activity or that can be treated by activating glucokinase that include, non-taxatively, diabetes mellitus, impaired glucose tolerance, IFG (impaired fasting glycemia), as well as other diseases and disorders such as those discussed herein.