UY30856A1 - NEW DERIVATIVES OF 2,4 DIANILINOPIRIMIDINAS, ITS PREPARATION, AS MEDICINES, PHARMACEUTICAL COMPOSITIONS AND MAINLY AS IKK INHIBITORS - Google Patents

NEW DERIVATIVES OF 2,4 DIANILINOPIRIMIDINAS, ITS PREPARATION, AS MEDICINES, PHARMACEUTICAL COMPOSITIONS AND MAINLY AS IKK INHIBITORS

Info

Publication number
UY30856A1
UY30856A1 UY30856A UY30856A UY30856A1 UY 30856 A1 UY30856 A1 UY 30856A1 UY 30856 A UY30856 A UY 30856A UY 30856 A UY30856 A UY 30856A UY 30856 A1 UY30856 A1 UY 30856A1
Authority
UY
Uruguay
Prior art keywords
mainly
dianilinopirimidinas
medicines
preparation
pharmaceutical compositions
Prior art date
Application number
UY30856A
Other languages
Spanish (es)
Inventor
Bosch Michael
Wagon Jean
Nguefack Jean-Flaubert
Bouaboula Monsif
Tonnerre Bernard
Casellas Pierre
Original Assignee
Sanofi Aventis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis filed Critical Sanofi Aventis
Publication of UY30856A1 publication Critical patent/UY30856A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Diabetes (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

La invencion se refiere a nuevos derivados de 2,4-dianilinopirimidinas, de formula (I), en todas sus formas isomericas y a sus sales, como medicamento principalmente como inhibidores de IKK, donde los sustituyentes son tales como se especifican en la memoria descriptiva y en las reivindicaciones.The invention relates to new derivatives of 2,4-dianylinopyrimidines, of formula (I), in all its isomeric forms and to its salts, as a medicament mainly as IKK inhibitors, where the substituents are as specified in the specification and in the claims.

UY30856A 2007-01-05 2008-01-04 NEW DERIVATIVES OF 2,4 DIANILINOPIRIMIDINAS, ITS PREPARATION, AS MEDICINES, PHARMACEUTICAL COMPOSITIONS AND MAINLY AS IKK INHIBITORS UY30856A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0700063A FR2911137B1 (en) 2007-01-05 2007-01-05 NOVEL 2,4-DIANILINOPYRIMIDE DERIVATIVES, THEIR PREPARATION AS MEDICAMENTS, PHARMACEUTICAL COMPOSITIONS AND IN PARTICULAR AS INHIBITORS OF IKK

Publications (1)

Publication Number Publication Date
UY30856A1 true UY30856A1 (en) 2008-09-02

Family

ID=38353639

Family Applications (1)

Application Number Title Priority Date Filing Date
UY30856A UY30856A1 (en) 2007-01-05 2008-01-04 NEW DERIVATIVES OF 2,4 DIANILINOPIRIMIDINAS, ITS PREPARATION, AS MEDICINES, PHARMACEUTICAL COMPOSITIONS AND MAINLY AS IKK INHIBITORS

Country Status (11)

Country Link
US (1) US20100035907A1 (en)
EP (1) EP2104673A2 (en)
JP (1) JP2010514820A (en)
CN (1) CN101605780A (en)
AR (1) AR064729A1 (en)
CA (1) CA2672955A1 (en)
CL (1) CL2008000021A1 (en)
FR (1) FR2911137B1 (en)
TW (1) TW200836740A (en)
UY (1) UY30856A1 (en)
WO (1) WO2008099072A2 (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2911140B1 (en) * 2007-01-05 2009-02-20 Sanofi Aventis Sa NOVEL 2-ANILINO 4-HETEROARYL PYRIMIDES DERIVATIVES, THEIR PREPARATION AS MEDICAMENTS, PHARMACEUTICAL COMPOSITIONS, AND IN PARTICULAR AS INHIBITORS OF IKK
FR2911139A1 (en) * 2007-01-05 2008-07-11 Sanofi Aventis Sa New 2,4-diaminopyrimidine derivatives useful for treating inflammatory diseases, diabetes or cancer
FR2911138B1 (en) * 2007-01-05 2009-02-20 Sanofi Aventis Sa NOVEL N, N'-2,4-DIANILINOPYRIMIDINE DERIVATIVES, THEIR PREPARATION AS MEDICAMENTS, PHARMACEUTICAL COMPOSITIONS AND IN PARTICULAR AS INHIBITORS OF IKK
WO2011107494A1 (en) 2010-03-03 2011-09-09 Sanofi Novel aromatic glycoside derivatives, medicaments containing said compounds, and the use thereof
WO2011157827A1 (en) 2010-06-18 2011-12-22 Sanofi Azolopyridin-3-one derivatives as inhibitors of lipases and phospholipases
TW201215388A (en) 2010-07-05 2012-04-16 Sanofi Sa (2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments
TW201221505A (en) 2010-07-05 2012-06-01 Sanofi Sa Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament
TW201215387A (en) 2010-07-05 2012-04-16 Sanofi Aventis Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament
EP2760862B1 (en) 2011-09-27 2015-10-21 Sanofi 6-(4-hydroxy-phenyl)-3-alkyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
US11175268B2 (en) 2014-06-09 2021-11-16 Biometry Inc. Mini point of care gas chromatographic test strip and method to measure analytes
AU2015274801B2 (en) 2014-06-09 2020-10-15 Biometry Inc. Low cost test strip and method to measure analyte
WO2017009751A1 (en) 2015-07-15 2017-01-19 Pfizer Inc. Pyrimidine derivatives
CN114859028A (en) 2016-07-19 2022-08-05 生物统计股份有限公司 Method and system for measuring analytes using batch calibratable test strips
CN113061117B (en) * 2021-03-30 2023-02-10 长治学院 2- ((5-chloro-2- (4-morpholine methylanilino) pyrimidine-4-yl) amino) benzamide derivative

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003095448A1 (en) * 2002-05-06 2003-11-20 Bayer Pharmaceuticals Corporation Pyridinyl amino pyrimidine derivatives useful for treating hyper-proliferative disorders
EP1598343A1 (en) * 2004-05-19 2005-11-23 Boehringer Ingelheim International GmbH 2-Arylaminopyrimidine derivatives as PLK inhibitors
MX2008000574A (en) * 2005-07-11 2008-03-14 Sanofi Aventis Novel 2,4-dianilinopyrimidine derivatives, the preparation thereof, their use as medicaments, pharmaceutical compositions and, in particular, as ikk inhibitors.

Also Published As

Publication number Publication date
EP2104673A2 (en) 2009-09-30
FR2911137A1 (en) 2008-07-11
WO2008099072A2 (en) 2008-08-21
US20100035907A1 (en) 2010-02-11
CN101605780A (en) 2009-12-16
TW200836740A (en) 2008-09-16
CL2008000021A1 (en) 2009-03-27
CA2672955A1 (en) 2008-08-21
AR064729A1 (en) 2009-04-22
JP2010514820A (en) 2010-05-06
FR2911137B1 (en) 2009-02-20
WO2008099072A3 (en) 2008-11-13

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Effective date: 20130205