UY30386A1 -
AMIDA COMPOUNDS OF ACID 3-AMINO-TIENO (2,3B (BETA) PIRIDINA-2- REPLACED CARBOXYLIC, PROCESSES FOR THEIR PREPARATION AND USES OF THE SAME
- Google Patents
AMIDA COMPOUNDS OF ACID 3-AMINO-TIENO (2,3B (BETA) PIRIDINA-2- REPLACED CARBOXYLIC, PROCESSES FOR THEIR PREPARATION AND USES OF THE SAME
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Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof
(AREA)
Abstract
Se describen compuestos de formula (I): en la que R1 y R4 se definen en este documento, que son utiles como inhibidores de la actividad de quisana del complejo de quisana Ikb (IKK). Por lo tanto, los compuestos son utiles en el tratamiento de enfermedades mediadas por IKK incluyendo enfermedades autoinmunes, enfermedades inflamatorias, enfermedades cardiovasculares y cáncer. También se describen composiciones farmacéuticas que comprenden estos compuestos y procesos para preparar estos compuestosCompounds of formula (I) are described: in which R1 and R4 are defined herein, which are useful as inhibitors of the kenyan activity of the Ikb (IKK) kiwana complex. Therefore, the compounds are useful in the treatment of IKK-mediated diseases including autoimmune diseases, inflammatory diseases, cardiovascular diseases and cancer. Pharmaceutical compositions comprising these compounds and processes for preparing these compounds are also described.
UY30386A2007-06-042007-06-04
AMIDA COMPOUNDS OF ACID 3-AMINO-TIENO (2,3B (BETA) PIRIDINA-2- REPLACED CARBOXYLIC, PROCESSES FOR THEIR PREPARATION AND USES OF THE SAME
UY30386A1
(en)
Compounds derived from piperidine 1,4 heterocycle substituted, procedure to prepare these compounds, pharmaceutical composition comprising them and their use for pain therapy and the treatment of diseases such as Alzheimer's, schizophrenia, anxiety and depression.