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Priority claimed from US10/658,834external-prioritypatent/US7611700B2/en
Application filed by Nautilus BiotechfiledCriticalNautilus Biotech
Publication of UY30293A1publicationCriticalpatent/UY30293A1/en
Se proporciona formulaciones de dosificacion oral de polipéptidos terapéuticos resistentes a proteasas. Las formulaciones de dosificacion para administracion por dosis y por DIA o por semana son mayores que la dosificacion subcutánea. Se incluye entre las formulaciones de dosificacion oral tabletas y cápsulas, incluyendo formas con recubrimiento entérico. Se proporciona métodos para el tratamiento y prevencion de enfermedades o condiciones que son tratables o prevenibles mediante la administracion de tales formulaciones de dosificacion oral de polipéptidos resistentes a las proteasas.Oral dosage formulations of protease-resistant therapeutic polypeptides are provided. Dosage formulations for administration by dose and by DAY or by week are greater than subcutaneous dosing. Tablets and capsules, including enteric coated forms, are included in the oral dosage formulations. Methods are provided for the treatment and prevention of diseases or conditions that are treatable or preventable by administering such oral dosage formulations of protease resistant polypeptides.
UY30293A2003-09-082007-04-18
ORAL DOSAGE FORMULATIONS OF PROTEASE RESISTANT POLYPEPTIDES AND USES OF THE SAME FOR TREATMENT
UY30293A1
(en)