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Priority claimed from US11/385,056external-prioritypatent/US7262210B2/en
Application filed by Janssen Pharmaceutica NvfiledCriticalJanssen Pharmaceutica Nv
Publication of UY29487A1publicationCriticalpatent/UY29487A1/en
La presente invención describe compuestos de Fórmula I donde X es: Y es: o una de sus sales aceptables para uso farmacéutico, para la profilaxis o el tratamiento de enfermedades y afecciones relacionadas con la actividad de trombina en un mamífero. La presente invención también se relaciona con un método novedoso de N-oxidación de heteroarilos nitrogenados.The present invention describes compounds of Formula I where X is: Y is: or one of its salts acceptable for pharmaceutical use, for the prophylaxis or treatment of diseases and conditions related to thrombin activity in a mammal. The present invention also relates to a novel method of N-oxidation of nitrogenous heteroaryls.
UY29487A2005-04-202006-04-20
"FLUORATED PIRIDINE N-OXIDES THROMBIN MODULATORS AND PROCESSES FOR N-OXIDATION OF NITROGEN HETEROARILES
UY29487A1
(en)
compounds, process for their manufacture, pharmaceutical compositions comprising them, their use and method for the treatment and / or prophylaxis of diseases
CRYSTAL FORMS OF 3- (2,6-DICLORO-3,5-DIMETOXI-PHENYL) -1- {6- [4- (4-ETIL-PIPERAZIN-1-IL) -PENYL-AMINO] -PIRIMIDIN-4- IL} -1-METHYL-UREA AND SALTS OF THE SAME
compound or a salt thereof, prodrug of a compound, pharmaceutical agent, peptidase inhibitor, compound or salt thereof, prodrug of a compound, pharmaceutical agent, peptidase inhibitor, use of a compound, and method to produce a compound
compound or a salt thereof, prodrug, pharmaceutical agent, peptidase inhibitor, use of a compound or prodrug thereof, and methods for preventing or treating disease, inhibiting peptidase in a mammal, and production of a compound