UY29409A1 - COMPOUNDS OF FTALAZINE, AZA- AND DIAZA-FTALAZINA AND METHODS OF USE - Google Patents

COMPOUNDS OF FTALAZINE, AZA- AND DIAZA-FTALAZINA AND METHODS OF USE

Info

Publication number
UY29409A1
UY29409A1 UY29409A UY29409A UY29409A1 UY 29409 A1 UY29409 A1 UY 29409A1 UY 29409 A UY29409 A UY 29409A UY 29409 A UY29409 A UY 29409A UY 29409 A1 UY29409 A1 UY 29409A1
Authority
UY
Uruguay
Prior art keywords
compounds
ftalazine
ftalazina
diaza
aza
Prior art date
Application number
UY29409A
Other languages
Spanish (es)
Inventor
Andrew Tasker
Anthony Reed
Bradley J Herberich
Dawei Zhang
Guo-Qiang Cao
James Richard Falsey
Kelvin K C Sham
Liping H Pettus
Maya C Thaman
Partha Pratimchakrabarti
Randall W Hungate
Robert M Rzasa
Shimin Xu
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Inc filed Critical Amgen Inc
Publication of UY29409A1 publication Critical patent/UY29409A1/en

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La presente invención comprende una nueva clase de compuestos útiles para la profilaxis y tratamiento de enfermedades mediadas por la quinasa proteica, incluyendo condiciones de inflamación y relacionadas. Los compuestos tienen una Fómula general I donde A1, A2, B, R2, R3, y R4, son según se definen aquí. La invención comprende también composiciones farmacéuticas que incluyen uno o más compuestos de la Fórmula I, los usos de dichos compuestos y composiciones para el tratamiento de las enfermedades mediadas por las quinasas, incluyendo artritis reumatoide, soriasis y otras afecciones inflamatorias, así como productos intermedios y procesos útiles para la preparacion de los compuestos de Fórmula I.The present invention comprises a new class of compounds useful for the prophylaxis and treatment of diseases mediated by protein kinase, including inflammation and related conditions. The compounds have a general formula I where A1, A2, B, R2, R3, and R4, are as defined herein. The invention also comprises pharmaceutical compositions that include one or more compounds of Formula I, the uses of said compounds and compositions for the treatment of kinase-mediated diseases, including rheumatoid arthritis, psoriasis and other inflammatory conditions, as well as intermediates and Useful processes for the preparation of the compounds of Formula I.

UY29409A 2005-03-03 2006-03-03 COMPOUNDS OF FTALAZINE, AZA- AND DIAZA-FTALAZINA AND METHODS OF USE UY29409A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US36712305A 2005-03-03 2005-03-03
US56900305P 2005-03-03 2005-03-03

Publications (1)

Publication Number Publication Date
UY29409A1 true UY29409A1 (en) 2006-10-31

Family

ID=38813148

Family Applications (1)

Application Number Title Priority Date Filing Date
UY29409A UY29409A1 (en) 2005-03-03 2006-03-03 COMPOUNDS OF FTALAZINE, AZA- AND DIAZA-FTALAZINA AND METHODS OF USE

Country Status (1)

Country Link
UY (1) UY29409A1 (en)

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Legal Events

Date Code Title Description
109 Application deemed to be withdrawn

Effective date: 20160805