UY28668A1 - TRANSDERMAL ADMINISTRATION HORMONES THAT DO NOT NEED PENETRATION POTENTIATORS - Google Patents

TRANSDERMAL ADMINISTRATION HORMONES THAT DO NOT NEED PENETRATION POTENTIATORS

Info

Publication number
UY28668A1
UY28668A1 UY28668A UY28668A UY28668A1 UY 28668 A1 UY28668 A1 UY 28668A1 UY 28668 A UY28668 A UY 28668A UY 28668 A UY28668 A UY 28668A UY 28668 A1 UY28668 A1 UY 28668A1
Authority
UY
Uruguay
Prior art keywords
hormones
patch
potentiators
transdermal administration
need
Prior art date
Application number
UY28668A
Other languages
Spanish (es)
Inventor
Michael Dittgen
Dirk Schenk
Thomas Langguth
Stefan Bracht
Petra Huber
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Priority to UY28668A priority Critical patent/UY28668A1/en
Publication of UY28668A1 publication Critical patent/UY28668A1/en

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)

Abstract

Un parche que comprende una capa de droga con un bajo contenido de hormonas, como por ejemplo gestodeno, y opcionalmente un estrógeno (por ejemplo etinilestradiol). Al aplicar el parche a una mujer, se consiguen niveles en plasma de al menos 1.0ng/ml de gestodeno en condiciones de estado estacionario sin necesidad de indorporar potenciadores de penetración ni mejoradores de permeación en la capa que contiene droga. También son satisfactorios los niveles en plasma de las hormonas que se consiguen durante todo un período de al menos 1 semana, haciendo que el parche se pueda aplicar para utilizarlo en anticoncepción femenina con el concepto de aplicar el parche una vez a la semana.A patch comprising a layer of drug with a low content of hormones, such as, for example, signodene, and optionally an estrogen (for example ethinyl estradiol). By applying the patch to a woman, plasma levels of at least 1.0ng / ml of signodene are achieved under steady state conditions without the need to induce penetration enhancers or permeation enhancers in the drug-containing layer. Plasma levels of hormones that are achieved over a period of at least 1 week are also satisfactory, making the patch can be applied for use in female contraception with the concept of applying the patch once a week.

UY28668A 2004-12-10 2004-12-10 TRANSDERMAL ADMINISTRATION HORMONES THAT DO NOT NEED PENETRATION POTENTIATORS UY28668A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
UY28668A UY28668A1 (en) 2004-12-10 2004-12-10 TRANSDERMAL ADMINISTRATION HORMONES THAT DO NOT NEED PENETRATION POTENTIATORS

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
UY28668A UY28668A1 (en) 2004-12-10 2004-12-10 TRANSDERMAL ADMINISTRATION HORMONES THAT DO NOT NEED PENETRATION POTENTIATORS

Publications (1)

Publication Number Publication Date
UY28668A1 true UY28668A1 (en) 2005-07-29

Family

ID=38813017

Family Applications (1)

Application Number Title Priority Date Filing Date
UY28668A UY28668A1 (en) 2004-12-10 2004-12-10 TRANSDERMAL ADMINISTRATION HORMONES THAT DO NOT NEED PENETRATION POTENTIATORS

Country Status (1)

Country Link
UY (1) UY28668A1 (en)

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Legal Events

Date Code Title Description
RDES Application refused

Effective date: 20190110