UY27794A1 - DERIVATIVES OF HETROXI TETRAHIDRO-NAFTALENILUREA - Google Patents

DERIVATIVES OF HETROXI TETRAHIDRO-NAFTALENILUREA

Info

Publication number
UY27794A1
UY27794A1 UY27794A UY27794A UY27794A1 UY 27794 A1 UY27794 A1 UY 27794A1 UY 27794 A UY27794 A UY 27794A UY 27794 A UY27794 A UY 27794A UY 27794 A1 UY27794 A1 UY 27794A1
Authority
UY
Uruguay
Prior art keywords
pain
derivatives
tetrahydro
useful
treatment
Prior art date
Application number
UY27794A
Other languages
Spanish (es)
Inventor
Takeshi Yura
Muneto Mogi
Dr Klaus Urbahns
Hiroshi Fujishima
Tsutomu Masuda
Toshiya Moriwaki
Nagahiro Yoshida
Toshio Kokubo
Masahiro Shiroo
Masaomi Tajimi
Yasuhiro Tsukimi
Noriyuki Yamamoto
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Priority to UY27794A priority Critical patent/UY27794A1/en
Publication of UY27794A1 publication Critical patent/UY27794A1/en

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Esta invención se refiere a derivados de tetrahidro-naftaleno y a sales de los mismos que son útiles como ingredientes activos de preparaciones farmacéuticas. Los derivados de tetrahidro-naftaleno de la presente invención tienen una excelente actividad como antagonistas de VR1 y son útiles para la profilaxis y tratamiento de enfermedades asociadas con la actividad de VR1, en particular para el tratamiento de la imperiosidad urinaria, vejiga superactiva, dolor crónico, dolor neuropático, dolor postoperatorio, dolor de artritis reumatoide, neuralgia, neuropatías, algesia, lesión de nervios, isquemia, neurodegeneración, apoplejía, incontinencia, trastornos inflamatorios tales como asma y COPD.This invention relates to tetrahydro-naphthalene derivatives and salts thereof that are useful as active ingredients in pharmaceutical preparations. The tetrahydro-naphthalene derivatives of the present invention have excellent activity as VR1 antagonists and are useful for the prophylaxis and treatment of diseases associated with VR1 activity, in particular for the treatment of urinary empire, superactive bladder, chronic pain. , neuropathic pain, postoperative pain, rheumatoid arthritis pain, neuralgia, neuropathies, algesia, nerve injury, ischemia, neurodegeneration, stroke, incontinence, inflammatory disorders such as asthma and COPD.

UY27794A 2003-05-06 2003-05-06 DERIVATIVES OF HETROXI TETRAHIDRO-NAFTALENILUREA UY27794A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
UY27794A UY27794A1 (en) 2003-05-06 2003-05-06 DERIVATIVES OF HETROXI TETRAHIDRO-NAFTALENILUREA

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
UY27794A UY27794A1 (en) 2003-05-06 2003-05-06 DERIVATIVES OF HETROXI TETRAHIDRO-NAFTALENILUREA

Publications (1)

Publication Number Publication Date
UY27794A1 true UY27794A1 (en) 2003-12-31

Family

ID=38812770

Family Applications (1)

Application Number Title Priority Date Filing Date
UY27794A UY27794A1 (en) 2003-05-06 2003-05-06 DERIVATIVES OF HETROXI TETRAHIDRO-NAFTALENILUREA

Country Status (1)

Country Link
UY (1) UY27794A1 (en)

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Legal Events

Date Code Title Description
109 Application deemed to be withdrawn

Effective date: 20161108