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Application filed by Pfizer Prod IncfiledCriticalPfizer Prod Inc
Priority to UY27576ApriorityCriticalpatent/UY27576A1/en
Publication of UY27576A1publicationCriticalpatent/UY27576A1/en
Acyclic And Carbocyclic Compounds In Medicinal Compositions
(AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines
(AREA)
Abstract
Esta invención se refiere a moléculas pequenas que son útiles en el tratamiento del crecimiento celular anormal, tal como el cáncer, en mamíferos. Esta invención también se refiere a un procedimiento de uso de tales moléculas pequenas en el tratamiento del crecimiento celular anormal en mamíferos, especialmente en seres humanos, y a composiciones farmacéuticas que contienen tales compuestos. La invención se refiere además a pequenas moléculas que son selectivas para el receptor erbB2 respecto al receptor erbB1, teniendo dicho inhibidor de erbB2 un intervalo de selectividades por erbB2 respecto a erbB1 entre 50-1500.This invention relates to small molecules that are useful in the treatment of abnormal cell growth, such as cancer, in mammals. This invention also relates to a method of using such small molecules in the treatment of abnormal cell growth in mammals, especially in humans, and to pharmaceutical compositions containing such compounds. The invention further relates to small molecules that are selective for the erbB2 receptor with respect to the erbB1 receptor, said erbB2 inhibitor having a range of selectivities for erbB2 with respect to erbB1 between 50-1500.
UY27576A2002-12-102002-12-10
SMALL MOLECULES FOR THE TREATMENT OF ABNORMAL CELL GROWTH
UY27576A1
(en)
Compounds derived from bi-, tri or non-aromatic polycycles, inhibitors of the 11-beta-hydroxysteroid dehydrogenase enzyme type i; process of preparation of these; pharmaceutical composition that includes them; use in the treatment of diseases such as obesity, diabetes and dyslipidemia, among others.
DERIVATIVES OF 2,3-DIHYDROBENZO [1,4] DIOXIN-2-ILMETILO AS ALFA2C ANTAGONISTS FOR USE IN THE TREATMENT OF CENTRAL AND PERIPHERAL NERVOUS SYSTEM DISEASES
7-ALQUINILAMINO- TRIAZOLOPIRIMIDINAS, PROCEDURES FOR ITS OBTAINING AND THE USE OF THE SAME TO CONTROL HARMFUL FUNGES, AS WELL AS PRODUCTS THAT CONTAIN IT