UY26206A1 - IL-8 RECEPTOR ANTAGONISTS. - Google Patents
IL-8 RECEPTOR ANTAGONISTS.Info
- Publication number
- UY26206A1 UY26206A1 UY26206A UY26206A UY26206A1 UY 26206 A1 UY26206 A1 UY 26206A1 UY 26206 A UY26206 A UY 26206A UY 26206 A UY26206 A UY 26206A UY 26206 A1 UY26206 A1 UY 26206A1
- Authority
- UY
- Uruguay
- Prior art keywords
- receptor antagonists
- treatment
- relates
- disease states
- mediated disease
- Prior art date
Links
- 108090001007 Interleukin-8 Proteins 0.000 title abstract 3
- 239000002464 receptor antagonist Substances 0.000 title 1
- 229940044551 receptor antagonist Drugs 0.000 title 1
- 102000004890 Interleukin-8 Human genes 0.000 abstract 2
- 235000013877 carbamide Nutrition 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- XKTZWUACRZHVAN-VADRZIEHSA-N interleukin-8 Chemical compound C([C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC=1C2=CC=CC=C2NC=1)NC(=O)[C@@H](NC(C)=O)CCSC)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N1[C@H](CCC1)C(=O)N1[C@H](CCC1)C(=O)N[C@@H](C)C(=O)N[C@H](CC(O)=O)C(=O)N[C@H](CCC(O)=O)C(=O)N[C@H](CC(O)=O)C(=O)N[C@H](CC=1C=CC(O)=CC=1)C(=O)N[C@H](CO)C(=O)N1[C@H](CCC1)C(N)=O)C1=CC=CC=C1 XKTZWUACRZHVAN-VADRZIEHSA-N 0.000 abstract 1
- 229940096397 interleukin-8 Drugs 0.000 abstract 1
- 230000001404 mediated effect Effects 0.000 abstract 1
- -1 phenyl ureas Chemical class 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/17—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/06—Antimalarials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Abstract
Esta invención se refiere a nuevas fenil-ureas útiles en el tratamiento de estados de enfermedad mediados por la quimiocina interleucina-8 (IL-8)This invention relates to novel phenyl ureas useful in the treatment of chemokine interleukin-8 (IL-8) mediated disease states.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US13967399P | 1999-06-16 | 1999-06-16 |
Publications (1)
Publication Number | Publication Date |
---|---|
UY26206A1 true UY26206A1 (en) | 2000-12-29 |
Family
ID=22487779
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
UY26206A UY26206A1 (en) | 1999-06-16 | 2000-06-13 | IL-8 RECEPTOR ANTAGONISTS. |
Country Status (20)
Country | Link |
---|---|
EP (1) | EP1185271A4 (en) |
JP (1) | JP2003501470A (en) |
KR (1) | KR20020012275A (en) |
CN (1) | CN1356902A (en) |
AR (1) | AR024349A1 (en) |
AU (1) | AU767000B2 (en) |
BR (1) | BR0011567A (en) |
CA (1) | CA2377391A1 (en) |
CO (1) | CO5190709A1 (en) |
CZ (1) | CZ20014491A3 (en) |
HU (1) | HUP0202004A3 (en) |
IL (1) | IL146515A0 (en) |
MX (1) | MXPA01013089A (en) |
NO (1) | NO20016102L (en) |
NZ (1) | NZ515609A (en) |
PL (1) | PL352222A1 (en) |
TR (1) | TR200103608T2 (en) |
UY (1) | UY26206A1 (en) |
WO (1) | WO2000076515A1 (en) |
ZA (1) | ZA200110205B (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0704651D0 (en) * | 2007-03-09 | 2007-04-18 | Ucl Business Plc | Composition |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2060682T3 (en) * | 1988-03-30 | 1994-12-01 | Warner Lambert Co | N - ((FENIL (2,6-DISUBSTITUTED)) - N'-ARIL) UREAS AS ANTI-HYPERCHOLESTEROLEMIC AND ANTIATHEROSCLEROTIC AGENTS. |
US5780483A (en) * | 1995-02-17 | 1998-07-14 | Smithkline Beecham Corporation | IL-8 receptor antagonists |
JP2001512096A (en) * | 1997-07-29 | 2001-08-21 | スミスクライン・ビーチャム・コーポレイション | IL-8 receptor antagonist |
-
2000
- 2000-06-13 UY UY26206A patent/UY26206A1/en not_active Application Discontinuation
- 2000-06-14 CO CO00044227A patent/CO5190709A1/en not_active Application Discontinuation
- 2000-06-14 AR ARP000102921A patent/AR024349A1/en not_active Application Discontinuation
- 2000-06-15 TR TR2001/03608T patent/TR200103608T2/en unknown
- 2000-06-15 KR KR1020017016141A patent/KR20020012275A/en not_active Application Discontinuation
- 2000-06-15 JP JP2001502848A patent/JP2003501470A/en not_active Withdrawn
- 2000-06-15 IL IL14651500A patent/IL146515A0/en unknown
- 2000-06-15 CA CA002377391A patent/CA2377391A1/en not_active Abandoned
- 2000-06-15 CN CN00809095A patent/CN1356902A/en active Pending
- 2000-06-15 PL PL00352222A patent/PL352222A1/en not_active Application Discontinuation
- 2000-06-15 AU AU58750/00A patent/AU767000B2/en not_active Ceased
- 2000-06-15 MX MXPA01013089A patent/MXPA01013089A/en unknown
- 2000-06-15 BR BR0011567-3A patent/BR0011567A/en not_active IP Right Cessation
- 2000-06-15 HU HU0202004A patent/HUP0202004A3/en unknown
- 2000-06-15 EP EP00944689A patent/EP1185271A4/en not_active Withdrawn
- 2000-06-15 CZ CZ20014491A patent/CZ20014491A3/en unknown
- 2000-06-15 WO PCT/US2000/016510 patent/WO2000076515A1/en not_active Application Discontinuation
- 2000-06-15 NZ NZ515609A patent/NZ515609A/en unknown
- 2000-12-12 ZA ZA200110205A patent/ZA200110205B/en unknown
-
2001
- 2001-12-14 NO NO20016102A patent/NO20016102L/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
AU767000B2 (en) | 2003-10-30 |
PL352222A1 (en) | 2003-08-11 |
MXPA01013089A (en) | 2002-06-04 |
IL146515A0 (en) | 2002-07-25 |
JP2003501470A (en) | 2003-01-14 |
EP1185271A1 (en) | 2002-03-13 |
BR0011567A (en) | 2002-03-05 |
HUP0202004A3 (en) | 2003-03-28 |
NO20016102L (en) | 2002-02-12 |
WO2000076515A1 (en) | 2000-12-21 |
CO5190709A1 (en) | 2002-08-29 |
AU5875000A (en) | 2001-01-02 |
TR200103608T2 (en) | 2002-06-21 |
CA2377391A1 (en) | 2000-12-21 |
ZA200110205B (en) | 2002-08-12 |
EP1185271A4 (en) | 2004-02-04 |
HUP0202004A2 (en) | 2002-10-28 |
CZ20014491A3 (en) | 2002-07-17 |
NO20016102D0 (en) | 2001-12-14 |
CN1356902A (en) | 2002-07-03 |
KR20020012275A (en) | 2002-02-15 |
NZ515609A (en) | 2003-11-28 |
AR024349A1 (en) | 2002-10-02 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
109 | Application deemed to be withdrawn |
Effective date: 20100520 |