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Application filed by Novartis AgfiledCriticalNovartis Ag
Priority to UY23272ApriorityCriticalpatent/UY23272A1/en
Publication of UY23272A1publicationCriticalpatent/UY23272A1/en
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Abstract
Un procedimiento para la elaboración de N,N-(dibenzohexatrienileno)urea, caracterizado porque, se hace reaccionar una correspondiente N,N-(dibenzohexatrienileno)amina, con ácido ciánico, en un solvente orgánico aprótico. El procedimiento se utiliza en particular para la preparación de 1,5-dibenzo(b,f)-azepin-5-carboxamida (conocida como Carbamazepin) útil como ingrediente activo medicamentoso.A process for the manufacture of N, N- (dibenzohexatrienylene) urea, characterized in that a corresponding N, N- (dibenzohexatrienylene) amine is reacted with cyanic acid in an aprotic organic solvent. The process is used in particular for the preparation of 1,5-dibenzo (b, f) -azepine-5-carboxamide (known as Carbamazepin) useful as a medicinal active ingredient.
UY23272A1991-08-121991-08-12
PROCEDURE FOR THE ELABORATION OF N-N (DIBENZOHEXATRIENILEN) UREA
UY23272A1
(en)
PROCESS FOR THE PREPARATION OF PHARMACEUTICAL COMPOSITIONS INCORPORATING AS ACTIVE INGREDIENT ISOXAZOL-4-CARBOXYLAMIDE AND HYDROXYLYLIDENE-CYANOOCETAMIDE
AMIDINE COMPOUNDS, PROCESS FOR THEIR PREPARATION, INTERMEDIARY COMPOUNDS, PHARMACEUTICAL FORMULATIONS THAT UNDERSTAND THEM, AND THEIR USE IN THE MANUFACTURE OF A MEDICINAL PRODUCT AS AN INHIBITOR OF NITRIC OXIDE, INDUCIBLE SYNTHESES.
4-AMINO-2- (IMIDAZOLIDIN-2-ON-L-YL) -PYRIMIDIN-5-CARBOXYLIC ACID- (N- (3-TRIFLUOROMETHYL-PHENYL) AMIDES) FOR PROPHYLAXY AND THERAPY OF THROMBOSES USING THEMSELVES USING USE ACTIVE MEDICINAL PRODUCTS