UST100403I4 - Hypolipidemic and anti-atherosclerotic 2- or 3-(monosubstituted-amino) phenyl compounds - Google Patents

Hypolipidemic and anti-atherosclerotic 2- or 3-(monosubstituted-amino) phenyl compounds Download PDF

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Publication number
UST100403I4
UST100403I4 US06/085,650 US8565079A UST100403I4 US T100403 I4 UST100403 I4 US T100403I4 US 8565079 A US8565079 A US 8565079A US T100403 I4 UST100403 I4 US T100403I4
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US
United States
Prior art keywords
hypolipidemic
atherosclerotic
monosubstituted
amino
phenyl compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
US06/085,650
Inventor
Robert G. Shepherd
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth Holdings LLC
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Priority to US06/085,650 priority Critical patent/UST100403I4/en
Application granted granted Critical
Publication of UST100403I4 publication Critical patent/UST100403I4/en
Pending legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A61K31/24Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
    • A61K31/245Amino benzoic acid types, e.g. procaine, novocaine

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)

Abstract

Hypolipidemic and anti-atherosclerotic 2- or 3-(monosubstituted-amino) phenyl compounds of the formulae: ##STR1## wherein R1 is a saturated or unsaturated hydrocarbon radical of 8-19 carbon atoms which may be branched or unbranched and which may contain one or more radicals selected from the group consisting of saturated or unsaturated cycloalkyl, substituted or unsubstituted aryl and substituted or unsubstituted heteroaryl; J is ##STR2## wherein Z is inter alia hydrogen, loweralkyl, hydroxy, loweralkoxy and loweralkoxyalkoxy, or J is carboxyloweralkyl, carboxyloweralkenyl, carboxyloweralkynyl, carboalkoxyloweralkyl, carboalkoxyloweralkenyl or carboalkoxyloweralkynyl.
US06/085,650 1979-10-17 1979-10-17 Hypolipidemic and anti-atherosclerotic 2- or 3-(monosubstituted-amino) phenyl compounds Pending UST100403I4 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US06/085,650 UST100403I4 (en) 1979-10-17 1979-10-17 Hypolipidemic and anti-atherosclerotic 2- or 3-(monosubstituted-amino) phenyl compounds

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/085,650 UST100403I4 (en) 1979-10-17 1979-10-17 Hypolipidemic and anti-atherosclerotic 2- or 3-(monosubstituted-amino) phenyl compounds

Publications (1)

Publication Number Publication Date
UST100403I4 true UST100403I4 (en) 1981-03-03

Family

ID=22193051

Family Applications (1)

Application Number Title Priority Date Filing Date
US06/085,650 Pending UST100403I4 (en) 1979-10-17 1979-10-17 Hypolipidemic and anti-atherosclerotic 2- or 3-(monosubstituted-amino) phenyl compounds

Country Status (1)

Country Link
US (1) UST100403I4 (en)

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