US8668375B2 - Bone cement mixing cartridge and method of use - Google Patents

Bone cement mixing cartridge and method of use Download PDF

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Publication number
US8668375B2
US8668375B2 US13/912,789 US201313912789A US8668375B2 US 8668375 B2 US8668375 B2 US 8668375B2 US 201313912789 A US201313912789 A US 201313912789A US 8668375 B2 US8668375 B2 US 8668375B2
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Prior art keywords
chamber
ingredient
bone cement
container
mixing
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Application number
US13/912,789
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US20130247516A1 (en
Inventor
H. Gene Hawkins
Imad K. Merkhan
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Encore Medical LP
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Biomet Manufacturing LLC
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Priority to US13/912,789 priority Critical patent/US8668375B2/en
Application filed by Biomet Manufacturing LLC filed Critical Biomet Manufacturing LLC
Publication of US20130247516A1 publication Critical patent/US20130247516A1/en
Assigned to BIOMET MANUFACTURING, LLC reassignment BIOMET MANUFACTURING, LLC CHANGE OF NAME (SEE DOCUMENT FOR DETAILS). Assignors: BIOMET MANUFACTURING CORP.
Assigned to BIOMET BIOLOGICS, LLC reassignment BIOMET BIOLOGICS, LLC ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: MERKHAN, IMAD K, HAWKINS, H. G.
Assigned to BIOMET MANUFACTURING CORP. reassignment BIOMET MANUFACTURING CORP. CORRECTIVE ASSIGNMENT TO CORRECT THE ASSIGNEE FROM "BIOMET BIOLOGICS, LLC" TO "BIOMET MANUFACTURING CORP." PREVIOUSLY RECORDED ON REEL 031927 FRAME 0427. ASSIGNOR(S) HEREBY CONFIRMS THE ASSIGNMENT. Assignors: MERKHAN, IMAD K., HAWKINS, H. G.
Priority to US14/201,105 priority patent/US9492947B2/en
Publication of US8668375B2 publication Critical patent/US8668375B2/en
Application granted granted Critical
Assigned to ZIMMER BIOMET HOLDINGS, INC. reassignment ZIMMER BIOMET HOLDINGS, INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: BIOMET MANUFACTURING, LLC
Assigned to ENCORE MEDICAL, L.P. (D/B/A/ DJO SURGICAL) reassignment ENCORE MEDICAL, L.P. (D/B/A/ DJO SURGICAL) ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: ZIMMER BIOMET HOLDINGS, INC.
Priority to US15/193,391 priority patent/US9974589B2/en
Priority to US15/985,462 priority patent/US10478242B2/en
Priority to US16/686,979 priority patent/US10959764B2/en
Assigned to JPMORGAN CHASE BANK, N.A., AS ADMINISTRATIVE AGENT reassignment JPMORGAN CHASE BANK, N.A., AS ADMINISTRATIVE AGENT SECURITY INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: ENCORE MEDICAL, L.P.
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
    • A61B17/88—Osteosynthesis instruments; Methods or means for implanting or extracting internal or external fixation devices
    • A61B17/8802—Equipment for handling bone cement or other fluid fillers
    • A61B17/8833—Osteosynthesis tools specially adapted for handling bone cement or fluid fillers; Means for supplying bone cement or fluid fillers to introducing tools, e.g. cartridge handling means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
    • A61B17/88—Osteosynthesis instruments; Methods or means for implanting or extracting internal or external fixation devices
    • A61B17/8802—Equipment for handling bone cement or other fluid fillers
    • A61B17/8805—Equipment for handling bone cement or other fluid fillers for introducing fluid filler into bone or extracting it
    • A61B17/8825—Equipment for handling bone cement or other fluid fillers for introducing fluid filler into bone or extracting it characterised by syringe details
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F27/00—Mixers with rotary stirring devices in fixed receptacles; Kneaders
    • B01F27/21—Mixers with rotary stirring devices in fixed receptacles; Kneaders characterised by their rotating shafts
    • B01F27/2122—Hollow shafts
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F31/00—Mixers with shaking, oscillating, or vibrating mechanisms
    • B01F31/40—Mixers with shaking, oscillating, or vibrating mechanisms with an axially oscillating rotary stirrer
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F31/00—Mixers with shaking, oscillating, or vibrating mechanisms
    • B01F31/44—Mixers with shaking, oscillating, or vibrating mechanisms with stirrers performing an oscillatory, vibratory or shaking movement
    • B01F31/441—Mixers with shaking, oscillating, or vibrating mechanisms with stirrers performing an oscillatory, vibratory or shaking movement performing a rectilinear reciprocating movement
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/50—Movable or transportable mixing devices or plants
    • B01F33/501—Movable mixing devices, i.e. readily shifted or displaced from one place to another, e.g. portable during use
    • B01F33/5011—Movable mixing devices, i.e. readily shifted or displaced from one place to another, e.g. portable during use portable during use, e.g. hand-held
    • B01F33/50112—Movable mixing devices, i.e. readily shifted or displaced from one place to another, e.g. portable during use portable during use, e.g. hand-held of the syringe or cartridge type
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/30—Driving arrangements; Transmissions; Couplings; Brakes
    • B01F35/32—Driving arrangements
    • B01F35/32005—Type of drive
    • B01F35/3202—Hand driven
    • B01F35/32021—Shaking by hand a portable receptacle or stirrer for mixing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/71—Feed mechanisms
    • B01F35/713—Feed mechanisms comprising breaking packages or parts thereof, e.g. piercing or opening sealing elements between compartments or cartridges
    • B01F35/7137—Piercing, perforating or melting membranes or closures which seal the compartments
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/71—Feed mechanisms
    • B01F35/716—Feed mechanisms characterised by the relative arrangement of the containers for feeding or mixing the components
    • B01F35/7162—A container being placed inside the other before contacting the contents
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/75—Discharge mechanisms
    • B01F35/754—Discharge mechanisms characterised by the means for discharging the components from the mixer
    • B01F35/75425—Discharge mechanisms characterised by the means for discharging the components from the mixer using pistons or plungers
    • B01F35/754251—Discharge mechanisms characterised by the means for discharging the components from the mixer using pistons or plungers reciprocating in the mixing receptacle
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29B—PREPARATION OR PRETREATMENT OF THE MATERIAL TO BE SHAPED; MAKING GRANULES OR PREFORMS; RECOVERY OF PLASTICS OR OTHER CONSTITUENTS OF WASTE MATERIAL CONTAINING PLASTICS
    • B29B7/00—Mixing; Kneading
    • B29B7/02—Mixing; Kneading non-continuous, with mechanical mixing or kneading devices, i.e. batch type
    • B29B7/22—Component parts, details or accessories; Auxiliary operations
    • B29B7/24—Component parts, details or accessories; Auxiliary operations for feeding
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29B—PREPARATION OR PRETREATMENT OF THE MATERIAL TO BE SHAPED; MAKING GRANULES OR PREFORMS; RECOVERY OF PLASTICS OR OTHER CONSTITUENTS OF WASTE MATERIAL CONTAINING PLASTICS
    • B29B7/00—Mixing; Kneading
    • B29B7/80—Component parts, details or accessories; Auxiliary operations
    • B29B7/84—Venting or degassing ; Removing liquids, e.g. by evaporating components
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B69/00—Unpacking of articles or materials, not otherwise provided for
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
    • A61B17/88—Osteosynthesis instruments; Methods or means for implanting or extracting internal or external fixation devices
    • A61B17/8802—Equipment for handling bone cement or other fluid fillers
    • A61B17/8805—Equipment for handling bone cement or other fluid fillers for introducing fluid filler into bone or extracting it
    • A61B17/8827—Equipment for handling bone cement or other fluid fillers for introducing fluid filler into bone or extracting it with filtering, degassing, venting or pressure relief means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
    • A61B17/88—Osteosynthesis instruments; Methods or means for implanting or extracting internal or external fixation devices
    • A61B17/8802—Equipment for handling bone cement or other fluid fillers
    • A61B17/8833—Osteosynthesis tools specially adapted for handling bone cement or fluid fillers; Means for supplying bone cement or fluid fillers to introducing tools, e.g. cartridge handling means
    • A61B2017/8838—Osteosynthesis tools specially adapted for handling bone cement or fluid fillers; Means for supplying bone cement or fluid fillers to introducing tools, e.g. cartridge handling means for mixing bone cement or fluid fillers

Definitions

  • the present disclosure relates to a mixing cartridge and, more particularly, relates to a bone cement mixing cartridge and method of use.
  • Bone cement is commonly used for bonding implants and prosthetics to bone and for other purposes. Bone cements are often made by mixing multiple ingredients, such as a liquid monomer and a polymeric powder, typically under a vacuum. Once the ingredients are mixed and the bone cement achieves the desired viscosity, the bone cement is delivered to the desired surface (e.g., the bone). Various bone cement mixing and delivery implements have been proposed for facilitating this process.
  • a container for bone cement includes a first member defining a chamber that is operable to contain a first ingredient.
  • the chamber also includes a second member movably coupled to the first member.
  • the second member includes a mixing device that is movably disposed within the first chamber, and the second member defines a second chamber that is operable to contain a second ingredient.
  • the container additionally includes an opening device that is operable to selectively open the second chamber and allow the second ingredient to enter from the second chamber into the first chamber.
  • the mixing device is movable within the first chamber to promote mixing of the first ingredient and the second ingredient to prepare the bone cement.
  • a container for bone cement.
  • the container includes a first member including a tube with an open first end and an open second end.
  • the first member also includes a cap covering the first end and a piston movably disposed within the tube adjacent the second end.
  • the tube, the cap, and the piston cooperate to define a first chamber.
  • the container further includes a pre-measured first ingredient disposed within the first chamber and a port defined in the cap that enables coupling the first chamber to a vacuum source.
  • the container includes a second member movably coupled to the first member.
  • the second member includes a rod, a mixing disc coupled to a first end of the rod, and a handle member that is coupled to a second end of the rod.
  • the second member additionally includes a sealing member.
  • the mixing disc is movably disposed in the first chamber, and the rod movably extends through the cap.
  • the handle member is disposed outside the first chamber, and the first end of the rod includes an aperture that is sealed by the sealing member.
  • the rod and the sealing member cooperate to define at least a portion of a second chamber.
  • the container further includes a pre-measured second ingredient disposed within the second chamber.
  • the container includes a piercing member disposed in the first chamber. The piercing member selectively pierces the sealing member to allow the second ingredient to enter from the second chamber into the first chamber.
  • the handle member is movable relative to the first member to move the mixing disc within the first chamber to promote mixing of the first ingredient and the second ingredient to prepare the bone cement.
  • a method of producing bone cement in a container includes a first member that defines a first chamber, a second member movably coupled to the first member, and an opening device.
  • the second member includes a mixing device movably disposed within the first chamber.
  • the method includes moving the second member of the container relative to the first member to move the mixing device in the first chamber.
  • the method also includes selectively opening a second chamber defined in the second member with the opening device to cause a second ingredient in the second chamber to enter the first chamber.
  • the method includes mixing the second ingredient with a first ingredient in the first chamber by moving the mixing device in the first chamber.
  • FIG. 1 is a perspective view of a bone cement container according to teachings of the present disclosure
  • FIG. 2 is a side view of the bone cement container of FIG. 1 in an initial stage of preparing the bone cement;
  • FIG. 3 is a side view of the bone cement container of FIG. 1 in an intermediate stage of preparing the bone cement;
  • FIG. 4 is a side view of the bone cement container of FIG. 1 in a latter stage of preparing the bone cement;
  • FIG. 5 is a side view of another embodiment of the bone cement container according to the teachings of the present disclosure.
  • FIG. 6 is a side view of another embodiment of the bone cement container according to the teachings of the present disclosure.
  • a container 10 for bone cement is illustrated.
  • the container 10 can include one or more features disclosed in U.S. Pat. No. 4,721,390, filed Oct. 17, 1985, U.S. Pat. No. 5,328,262, filed Feb. 3, 1993, U.S. Pat. No. 5,501,520, filed Apr. 26, 1994, U.S. Patent Publication No. 2006/0109737, filed Apr. 29, 2005, and/or U.S. Patent Publication No. 2007/0016215, filed Aug. 2, 2005, each of which is incorporated by reference in its entirety.
  • the container 10 includes a first member 12 which defines a first chamber 14 .
  • a first ingredient 16 for the preparation of bone cement is contained within the first chamber 14 .
  • the container further includes a second member 18 , which is movably coupled to the first member 12 .
  • the second member 18 defines a second chamber 20 .
  • a second ingredient 22 for the preparation of bone cement is contained within the second chamber 20 .
  • the container 10 includes an opening device 24 that selectively opens the second chamber 20 and allows the second ingredient 22 to enter from the second chamber 20 into the first chamber 14 .
  • the first and second ingredients 16 , 22 are mixed, bone cement is formed in the first chamber 14 . This bone cement can then be dispensed from the first chamber 14 onto any suitable surface (e.g., bone, etc.).
  • the first ingredient 16 is a polymeric powder and the second ingredient 22 is a liquid monomer. It will be appreciated that the first and second ingredients 16 , 22 can be of any suitable type. For instance, in some embodiments, the first ingredient 16 is ceramic powder. Furthermore, in some embodiments, the second ingredient 22 is an aqueous setting solution. It will also be appreciated that the first ingredient 16 can be contained within the second chamber 20 while the second ingredient 22 can be contained within the first chamber 12 .
  • the first and second ingredients 16 , 22 are pre-measured and provided in the first and second chambers 14 , 20 , respectively.
  • the container 10 can be packaged and sold so as to be ready for use to make bone cement.
  • the container 10 provides a convenient and accurate means for making bone cement.
  • the first member 12 can include a tube 26 .
  • the tube 26 is cylindrical so as to define a linear axis X.
  • the tube 26 includes a first open end 28 and a second open end 30 at opposite axial ends of the tube 26 .
  • the first open end 28 is threaded on its outer surface.
  • the first member 12 can also include a cap 32 , which is disposed on and substantially covers the first end 28 of the tube 26 .
  • the cap 32 includes threading on an interior surface for threadably coupling to the first end 28 of the tube 26 .
  • the first member 12 can include a piston 36 .
  • the piston 36 is movably disposed within the tube 26 to change a volume of the first chamber 14 as will be described in greater below.
  • the piston 36 In an initial state of the container 10 represented in FIG. 1 (i.e., before the first and second ingredients 16 , 22 are mixed), the piston 36 is disposed adjacent the second end 30 of the tube 26 .
  • the piston 36 moves along the axis X toward the first end 28 once the bone cement is produced as will be described in greater detail below.
  • the container 10 can also include a port 38 .
  • the port 38 is defined in the cap 32 .
  • the port 38 is threaded on an outer surface.
  • the port 38 enables coupling the first chamber 14 to a vacuum source 40 ( FIGS. 2 and 3 ).
  • the container 10 includes a dispensing tube 42 that removably couples to the port 38 and enables dispensing of the bone cement from the first chamber 14 ( FIG. 4 ).
  • the second member 18 is moveable along the axis X relative to the first member 12 to promote mixing of the first and second ingredients 16 , 22 .
  • the second member 12 includes a mixing device 44 .
  • the mixing device 44 can be flat and disc-shaped with a plurality of legs 46 that extend transversely from the axis X.
  • the legs 46 are disposed in spaced relationship relative to each other so as to define a space 48 between each of the legs 46 .
  • each leg 46 includes an enlarged head 50 at a terminal end thereof.
  • the mixing device 44 is movably disposed in the first chamber 14 . More specifically, in some embodiments, the mixing device 44 is moveable along the axis X toward the first and second ends, 28 , 30 of the tube 26 . Also, in some embodiments, the legs 46 are long enough to substantially span the width of the tube 26 .
  • the second member 18 can also include an extension member 52 .
  • the extension member 52 is elongate and rod-shaped.
  • the extension member 52 includes a first end 54 and a second end 56 that is fixedly coupled to the mixing device 44 .
  • the extension member 52 movably extends through a central aperture 58 in the cap 32 so as to be substantially aligned with the axis X. As such, the first end 54 of the extension member 52 extends out of the first chamber 14 .
  • the extension member 52 defines a passage 60 therein.
  • the passage 60 partially defines the second chamber 20 .
  • the extension member 52 includes an aperture 62 ( FIGS. 2 and 3 ) at the second end 56 of the extension member 52 .
  • the second ingredient 22 flows from the second chamber 20 into the first chamber 14 through the aperture 62 .
  • the second member 18 can also include a handle member 64 .
  • the handle member 64 is disc-shaped and is centered about the axis X.
  • the handle member 64 is fixedly coupled to the first end 54 of the extension member 52 . As such, the handle member 64 is disposed outside the first chamber 14 of the container 10 .
  • the handle member 64 is substantially hollow so as to define a handle chamber 66 therein.
  • the handle chamber 66 partially defines the second chamber 20 .
  • the handle chamber 66 is in communication (e.g., fluid communication) with the passage 60 of the extension member 52 .
  • the handle member 64 and the extension member 52 are moveable relative to the first member 12 to move the mixing device 44 within the first chamber 14 to promote mixing of the first ingredient and the second ingredient, 16 , 22 and to prepare the bone cement.
  • the second member 18 can include a sealing member 68 ( FIGS. 2 and 3 ).
  • the sealing member 68 is a thin membrane that seals the aperture 62 of the extension member 52 .
  • the sealing member can be made of any suitable material, such as aluminum foil coated with polyethylene.
  • the handle chamber 64 and the passage 60 collectively define the second chamber 20 .
  • the handle member 64 , the extension member 52 , and the sealing member 68 cooperate to define the volume of the second chamber 20 .
  • the tube 26 , the cap 32 , and the piston 36 cooperate to define the volume of the first chamber 14 .
  • the first ingredient 16 remains independent of the second ingredient 22 until the sealing member 68 unseals the aperture 62 of the extension member 52 .
  • the opening device 24 can include a base 70 and a piercing member 72 .
  • the base 70 is disc-shaped, and the piercing member 72 comes to a sharpened point.
  • the opening device 24 is disposed within the first chamber 14 between the piston 36 and the mixing device 44 .
  • the opening device 24 is supported on the piston 36 such that the sharpened point of the piercing member 72 faces the sealing member 68 .
  • the passage 60 , the sealing member 68 , and the piercing member 72 are substantially aligned along the axis X.
  • the width of the base 70 is substantially less than the width of the first chamber 14 .
  • the opening device 24 selectively opens the second chamber 20 by piercing the sealing member 68 , thereby selectively unsealing the aperture 62 of the extension member 52 .
  • the container 10 can also include a guard member 74 ( FIG. 1 ).
  • the guard member 74 selectively limits movement of the handle member 64 , the extension member 52 , and the mixing device 44 toward the opening device 24 . As such, the guard member 74 reduces the likelihood of inadvertent piercing of the sealing member 68 by the piercing member 72 of the opening device 24 .
  • the guard member 74 includes a relatively thin, flexible strip of material or membrane that is wrapped around the container 10 and disposed between the handle member 64 and the cap 32 .
  • the guard member 74 includes one or more removable rods that extend between the handle member 64 and the cap 32 .
  • the guard member 74 is removably coupled to the handle member 64 and/or the cap 32 .
  • the guard member 74 can be integral, molded, glued, snap-fit, welded or otherwise removably coupled to the handle member 64 and the cap 32 .
  • the guard member 74 seals the space between the handle member 64 and the cap 32 such that the port 38 is substantially sealed from contamination.
  • the guard member 74 can be disposed anywhere on the container 10 , including inside the first chamber 14 .
  • the guard member 74 is first removed from the handle member 64 and the cap 32 . This exposes the port 38 and allows movement of the second member 18 relative to the first member 12 .
  • the vacuum source 40 is operatively coupled to the first chamber 14 via the port 38 .
  • a filter device 80 is disposed adjacent the first end 28 and at least partially over the port 38 for inhibiting bone cement and/or the first or second ingredients 16 , 22 from being sucked into the vacuum source 40 .
  • the user grasps the handle member 64 and pushes the handle member 64 downward along the axis X such that the mixing device 44 and the sealing member 68 move toward the piercing member 72 ( FIG. 2 ).
  • the piercing member 72 pierces through the sealing member 68 and unseals the aperture 62 .
  • the second ingredient 22 flows from the handle chamber 66 and the passage 60 through the aperture 62 and into the first chamber 14 to mix with the first ingredient 16 .
  • the second ingredient 22 flows out of small openings pierced in the sealing member 68 , and these openings are sufficiently small to inhibit backflow from the first chamber 14 to the passage 60 .
  • the piercing member 72 substantially plugs the aperture 62 once the second ingredient 22 flows out into the first chamber 14 to inhibit backflow from the first chamber 14 into the passage 60 .
  • the passage 60 includes a one way valve that allows the second ingredient 22 to flow into the first chamber 14 but that inhibits backflow from the first chamber 14 into the passage 60 .
  • the user can agitate the mixture of the first and second ingredients 16 , 22 by grasping the handle member 64 and moving the mixing device 44 up and down along the axis X and/or rotating the mixing device 44 about the axis X.
  • the legs 46 and the heads 50 of the mixing device 44 facilitate mixing of the first and second ingredients 16 , 22 .
  • a reaction occurs to form the bone cement 90 ( FIG. 4 ).
  • the user grasps the handle member 64 and moves the handle member 64 , the extension member 52 , and the mixing device 44 upward along the axis X toward the first end 28 of the tube 26 .
  • the opening device 24 is detachably supported by the piston 36 such that the opening device 24 remains frictionally attached to the second member 18 once the piercing member 72 pierces the sealing member 68 , and movement of the second member 18 toward the first end 28 of the tube 26 pulls the opening device 24 toward the first end 28 of the tube 26 ( FIG. 4 ).
  • the piston 36 moves selectively away from the second end 30 .
  • the piston 36 and the tube 26 can include corresponding locking tabs. The locking tabs retain the piston 36 in position adjacent the second end 30 . Then, when the user so chooses, the piston 36 can turn the piston 36 about the axis X to unlock the corresponding locking tabs and allow the piston 36 to move toward the first end 28 of the tube 26 .
  • the extension member 52 can be broken just above the cap 32 , and the filter device 80 can be removed from the port 38 .
  • the dispensing tube 42 can be threaded to the port 38 , and the container 10 can be loaded into a dispensing device, such as a bone cementing gun (not specifically shown) for dispensing the bone cement 90 to the intended area.
  • a dispensing device such as a bone cementing gun (not specifically shown) for dispensing the bone cement 90 to the intended area.
  • the opening device 24 substantially seals the passage 60 such that the bone cement 90 is unlikely to flow out of the first chamber 14 through the passage 60 .
  • the width of the base 70 is such that the bone cement 90 is able to bypass the base 70 and flow out of the first chamber 14 through the port 38 .
  • FIG. 5 a container 110 is illustrated according to various other embodiments of the present disclosure. Features that are similar to those of the container 10 of FIGS. 1-4 are identified with similar reference numerals increased by 100.
  • the container 110 includes an opening device 124 wherein the piercing member 172 remains attached to the piston 136 .
  • the piercing member 172 has a length sufficient enough to extend from the piston 136 and into the aperture 162 to substantially plug the aperture 162 .
  • the length of the piercing member 172 is approximately two centimeters in some embodiments. Because the piercing member 172 substantially plugs the aperture 162 , the bone cement 190 is unlikely to backflow into the passage 160 . Also, the bone cement 190 is less likely to be contaminated.
  • FIG. 6 a container 210 is illustrated according to various other embodiments of the present disclosure. Features that are similar to those of the container 10 of FIG. 1-4 are identified with similar reference numerals increased by 200.
  • the container 210 includes a first member 212 and a second member 218 .
  • the second member 218 includes a handle member 264 and an extension member 252 .
  • the second chamber 220 is defined substantially within only the extension member 252 .
  • the extension member 252 can be of any suitable width, diameter, length, or other dimension so as to encapsulate a predetermined amount of the second ingredient 222 .
  • the piercing member 272 pierces the sealing member 268 . This unseals the aperture 262 in the extension member 252 , thereby allowing the second ingredient 222 to flow out from the second chamber 220 and into the first chamber 214 to mix with the first ingredient 216 . It will be appreciated that the container 210 can be simpler to manufacture because the second chamber 220 is defined substantially within only the extension member 252 .
  • the container 10 allows for convenient manufacture of bone cement 90 because the first and second ingredients 16 , 22 can be pre-measured and disposed within the first and second chambers 14 , 20 , respectively and because mixing the ingredients 16 , 22 can be performed with relatively few steps. Also, the first and second ingredients 16 , 22 can be mixed substantially without exposing the user to harmful vapors because the mixing can be performed under vacuum. Moreover, the sterility of the ingredients 16 , 22 and ultimately the bone cement 90 can be ensured using the container 10 . Furthermore, the container 10 is relatively compact for additional convenience.

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  • Orthopedic Medicine & Surgery (AREA)
  • Surgery (AREA)
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Abstract

A container for bone cement includes a first member defining a chamber, which contains a first ingredient. The chamber also includes a second member movably coupled to the first member. The second member includes a mixing device that is movably disposed within the first chamber, and the second member defines a second chamber containing a second ingredient. The container additional includes an opening device that selectively opens the second chamber and allows the second ingredient to enter from the second chamber into the first chamber. The mixing device is movable within the first chamber to promote mixing of the first ingredient and the second ingredient to prepare the bone cement. A corresponding method of preparing bone cement is also disclosed.

Description

CROSS-REFFERENCE TO RELATED APPLICATIONS
This application is a divisional of U.S. patent application Ser. No. 12/196,394 filed on Aug. 22, 2008, now U.S. Pat. No. 8,480,289. The entire disclosure of the above application is incorporated herein by reference.
FIELD
The present disclosure relates to a mixing cartridge and, more particularly, relates to a bone cement mixing cartridge and method of use.
BACKGROUND
The statements in this section merely provide background information related to the present disclosure and may not constitute prior art.
Bone cement is commonly used for bonding implants and prosthetics to bone and for other purposes. Bone cements are often made by mixing multiple ingredients, such as a liquid monomer and a polymeric powder, typically under a vacuum. Once the ingredients are mixed and the bone cement achieves the desired viscosity, the bone cement is delivered to the desired surface (e.g., the bone). Various bone cement mixing and delivery implements have been proposed for facilitating this process.
Although these conventional implements have been adequate for intended uses, they suffer from certain disadvantages. For instance, some containers allow harmful vapors to escape. Furthermore, it can be difficult to ensure proper proportions of the ingredients have been added to the container, and an improper ratio of ingredients can compromise the properties of the bone cement. Additionally, these implements can include a relatively large number of separate components, making them somewhat awkward to use. For instance, ingredients manually decanted from pouches or other containers can cause spills resulting in a messy and potentially dangerous waste of ingredients.
SUMMARY
A container for bone cement is disclosed that includes a first member defining a chamber that is operable to contain a first ingredient. The chamber also includes a second member movably coupled to the first member. The second member includes a mixing device that is movably disposed within the first chamber, and the second member defines a second chamber that is operable to contain a second ingredient. The container additionally includes an opening device that is operable to selectively open the second chamber and allow the second ingredient to enter from the second chamber into the first chamber. The mixing device is movable within the first chamber to promote mixing of the first ingredient and the second ingredient to prepare the bone cement.
In another aspect, a container is disclosed for bone cement. The container includes a first member including a tube with an open first end and an open second end. The first member also includes a cap covering the first end and a piston movably disposed within the tube adjacent the second end. The tube, the cap, and the piston cooperate to define a first chamber. The container further includes a pre-measured first ingredient disposed within the first chamber and a port defined in the cap that enables coupling the first chamber to a vacuum source. Additionally, the container includes a second member movably coupled to the first member. The second member includes a rod, a mixing disc coupled to a first end of the rod, and a handle member that is coupled to a second end of the rod. The second member additionally includes a sealing member. The mixing disc is movably disposed in the first chamber, and the rod movably extends through the cap. The handle member is disposed outside the first chamber, and the first end of the rod includes an aperture that is sealed by the sealing member. The rod and the sealing member cooperate to define at least a portion of a second chamber. The container further includes a pre-measured second ingredient disposed within the second chamber. Also, the container includes a piercing member disposed in the first chamber. The piercing member selectively pierces the sealing member to allow the second ingredient to enter from the second chamber into the first chamber. The handle member is movable relative to the first member to move the mixing disc within the first chamber to promote mixing of the first ingredient and the second ingredient to prepare the bone cement.
A method of producing bone cement in a container is also disclosed. The container includes a first member that defines a first chamber, a second member movably coupled to the first member, and an opening device. The second member includes a mixing device movably disposed within the first chamber. The method includes moving the second member of the container relative to the first member to move the mixing device in the first chamber. The method also includes selectively opening a second chamber defined in the second member with the opening device to cause a second ingredient in the second chamber to enter the first chamber. Also, the method includes mixing the second ingredient with a first ingredient in the first chamber by moving the mixing device in the first chamber.
Further areas of applicability will become apparent from the description provided herein. It should be understood that the description and specific examples are intended for purposes of illustration only and are not intended to limit the scope of the present disclosure.
DRAWINGS
The drawings described herein are for illustration purposes only and are not intended to limit the scope of the present disclosure in any way.
FIG. 1 is a perspective view of a bone cement container according to teachings of the present disclosure;
FIG. 2 is a side view of the bone cement container of FIG. 1 in an initial stage of preparing the bone cement;
FIG. 3 is a side view of the bone cement container of FIG. 1 in an intermediate stage of preparing the bone cement;
FIG. 4 is a side view of the bone cement container of FIG. 1 in a latter stage of preparing the bone cement;
FIG. 5 is a side view of another embodiment of the bone cement container according to the teachings of the present disclosure; and
FIG. 6 is a side view of another embodiment of the bone cement container according to the teachings of the present disclosure.
 DETAILED DESCRIPTION
The following description is merely exemplary in nature and is not intended to limit the present disclosure, application, or uses. It should be understood that throughout the drawings, corresponding reference numerals indicate like or corresponding parts and features.
Initially referring to FIG. 1, a container 10 for bone cement is illustrated. It will be appreciated that the container 10 can include one or more features disclosed in U.S. Pat. No. 4,721,390, filed Oct. 17, 1985, U.S. Pat. No. 5,328,262, filed Feb. 3, 1993, U.S. Pat. No. 5,501,520, filed Apr. 26, 1994, U.S. Patent Publication No. 2006/0109737, filed Apr. 29, 2005, and/or U.S. Patent Publication No. 2007/0016215, filed Aug. 2, 2005, each of which is incorporated by reference in its entirety.
Generally, the container 10 includes a first member 12 which defines a first chamber 14. A first ingredient 16 for the preparation of bone cement is contained within the first chamber 14. The container further includes a second member 18, which is movably coupled to the first member 12. The second member 18 defines a second chamber 20. A second ingredient 22 for the preparation of bone cement is contained within the second chamber 20. Furthermore, the container 10 includes an opening device 24 that selectively opens the second chamber 20 and allows the second ingredient 22 to enter from the second chamber 20 into the first chamber 14. When the first and second ingredients 16, 22 are mixed, bone cement is formed in the first chamber 14. This bone cement can then be dispensed from the first chamber 14 onto any suitable surface (e.g., bone, etc.).
In some embodiments, the first ingredient 16 is a polymeric powder and the second ingredient 22 is a liquid monomer. It will be appreciated that the first and second ingredients 16, 22 can be of any suitable type. For instance, in some embodiments, the first ingredient 16 is ceramic powder. Furthermore, in some embodiments, the second ingredient 22 is an aqueous setting solution. It will also be appreciated that the first ingredient 16 can be contained within the second chamber 20 while the second ingredient 22 can be contained within the first chamber 12.
Furthermore, in some embodiments, the first and second ingredients 16, 22 are pre-measured and provided in the first and second chambers 14, 20, respectively. As such, the container 10 can be packaged and sold so as to be ready for use to make bone cement. Thus, the container 10 provides a convenient and accurate means for making bone cement.
As shown in FIGS. 1-3, the first member 12 can include a tube 26. In some embodiments, the tube 26 is cylindrical so as to define a linear axis X. The tube 26 includes a first open end 28 and a second open end 30 at opposite axial ends of the tube 26. In some embodiments, the first open end 28 is threaded on its outer surface.
The first member 12 can also include a cap 32, which is disposed on and substantially covers the first end 28 of the tube 26. In some embodiments, the cap 32 includes threading on an interior surface for threadably coupling to the first end 28 of the tube 26.
Moreover, the first member 12 can include a piston 36. The piston 36 is movably disposed within the tube 26 to change a volume of the first chamber 14 as will be described in greater below. In an initial state of the container 10 represented in FIG. 1 (i.e., before the first and second ingredients 16, 22 are mixed), the piston 36 is disposed adjacent the second end 30 of the tube 26. The piston 36 moves along the axis X toward the first end 28 once the bone cement is produced as will be described in greater detail below.
The container 10 can also include a port 38. In some embodiments, the port 38 is defined in the cap 32. Also, in some embodiments, the port 38 is threaded on an outer surface. As will be described, the port 38 enables coupling the first chamber 14 to a vacuum source 40 (FIGS. 2 and 3). Furthermore, in some embodiments, the container 10 includes a dispensing tube 42 that removably couples to the port 38 and enables dispensing of the bone cement from the first chamber 14 (FIG. 4).
In some embodiments, the second member 18 is moveable along the axis X relative to the first member 12 to promote mixing of the first and second ingredients 16, 22. Accordingly, in some embodiments, the second member 12 includes a mixing device 44. The mixing device 44 can be flat and disc-shaped with a plurality of legs 46 that extend transversely from the axis X. The legs 46 are disposed in spaced relationship relative to each other so as to define a space 48 between each of the legs 46. Furthermore, each leg 46 includes an enlarged head 50 at a terminal end thereof. The mixing device 44 is movably disposed in the first chamber 14. More specifically, in some embodiments, the mixing device 44 is moveable along the axis X toward the first and second ends, 28, 30 of the tube 26. Also, in some embodiments, the legs 46 are long enough to substantially span the width of the tube 26.
The second member 18 can also include an extension member 52. In some embodiments, the extension member 52 is elongate and rod-shaped. The extension member 52 includes a first end 54 and a second end 56 that is fixedly coupled to the mixing device 44. The extension member 52 movably extends through a central aperture 58 in the cap 32 so as to be substantially aligned with the axis X. As such, the first end 54 of the extension member 52 extends out of the first chamber 14.
The extension member 52 defines a passage 60 therein. The passage 60 partially defines the second chamber 20. Furthermore, the extension member 52 includes an aperture 62 (FIGS. 2 and 3) at the second end 56 of the extension member 52. As will be described in greater detail, the second ingredient 22 flows from the second chamber 20 into the first chamber 14 through the aperture 62.
The second member 18 can also include a handle member 64. In some embodiments, the handle member 64 is disc-shaped and is centered about the axis X. The handle member 64 is fixedly coupled to the first end 54 of the extension member 52. As such, the handle member 64 is disposed outside the first chamber 14 of the container 10.
In some embodiments, the handle member 64 is substantially hollow so as to define a handle chamber 66 therein. The handle chamber 66 partially defines the second chamber 20. The handle chamber 66 is in communication (e.g., fluid communication) with the passage 60 of the extension member 52. As will be described, the handle member 64 and the extension member 52 are moveable relative to the first member 12 to move the mixing device 44 within the first chamber 14 to promote mixing of the first ingredient and the second ingredient, 16, 22 and to prepare the bone cement.
Furthermore, the second member 18 can include a sealing member 68 (FIGS. 2 and 3). In some embodiments, the sealing member 68 is a thin membrane that seals the aperture 62 of the extension member 52. It will be appreciated that the sealing member can be made of any suitable material, such as aluminum foil coated with polyethylene.
Thus, the handle chamber 64 and the passage 60 collectively define the second chamber 20. In other words, the handle member 64, the extension member 52, and the sealing member 68 cooperate to define the volume of the second chamber 20. Likewise, the tube 26, the cap 32, and the piston 36 cooperate to define the volume of the first chamber 14. It will be appreciated that the first ingredient 16 remains independent of the second ingredient 22 until the sealing member 68 unseals the aperture 62 of the extension member 52.
Additionally, the opening device 24 can include a base 70 and a piercing member 72. In some embodiments, the base 70 is disc-shaped, and the piercing member 72 comes to a sharpened point. The opening device 24 is disposed within the first chamber 14 between the piston 36 and the mixing device 44. In some embodiments, the opening device 24 is supported on the piston 36 such that the sharpened point of the piercing member 72 faces the sealing member 68. Furthermore, in some embodiments, the passage 60, the sealing member 68, and the piercing member 72 are substantially aligned along the axis X. Moreover, in some embodiments, the width of the base 70 is substantially less than the width of the first chamber 14. As will be described, the opening device 24 selectively opens the second chamber 20 by piercing the sealing member 68, thereby selectively unsealing the aperture 62 of the extension member 52.
Moreover, the container 10 can also include a guard member 74 (FIG. 1). Generally, the guard member 74 selectively limits movement of the handle member 64, the extension member 52, and the mixing device 44 toward the opening device 24. As such, the guard member 74 reduces the likelihood of inadvertent piercing of the sealing member 68 by the piercing member 72 of the opening device 24. In some embodiments, the guard member 74 includes a relatively thin, flexible strip of material or membrane that is wrapped around the container 10 and disposed between the handle member 64 and the cap 32. In other embodiments, the guard member 74 includes one or more removable rods that extend between the handle member 64 and the cap 32. Furthermore, in some embodiments, the guard member 74 is removably coupled to the handle member 64 and/or the cap 32. The guard member 74 can be integral, molded, glued, snap-fit, welded or otherwise removably coupled to the handle member 64 and the cap 32. Additionally, in some embodiments, the guard member 74 seals the space between the handle member 64 and the cap 32 such that the port 38 is substantially sealed from contamination. Also, the guard member 74 can be disposed anywhere on the container 10, including inside the first chamber 14.
Thus, in order to make and produce bone cement using the pre-packaged container 10 represented in FIG. 1, the guard member 74 is first removed from the handle member 64 and the cap 32. This exposes the port 38 and allows movement of the second member 18 relative to the first member 12.
Then, the vacuum source 40 is operatively coupled to the first chamber 14 via the port 38. In some embodiments, a filter device 80 is disposed adjacent the first end 28 and at least partially over the port 38 for inhibiting bone cement and/or the first or second ingredients 16, 22 from being sucked into the vacuum source 40.
Next, the user grasps the handle member 64 and pushes the handle member 64 downward along the axis X such that the mixing device 44 and the sealing member 68 move toward the piercing member 72 (FIG. 2). Eventually, the piercing member 72 pierces through the sealing member 68 and unseals the aperture 62. Because of the vacuum provided by the vacuum source 40, the second ingredient 22 flows from the handle chamber 66 and the passage 60 through the aperture 62 and into the first chamber 14 to mix with the first ingredient 16. In some embodiments, once the sealing member 68 is pierced, the second ingredient 22 flows out of small openings pierced in the sealing member 68, and these openings are sufficiently small to inhibit backflow from the first chamber 14 to the passage 60. Also, in some embodiments, the piercing member 72 substantially plugs the aperture 62 once the second ingredient 22 flows out into the first chamber 14 to inhibit backflow from the first chamber 14 into the passage 60. In still further embodiments, the passage 60 includes a one way valve that allows the second ingredient 22 to flow into the first chamber 14 but that inhibits backflow from the first chamber 14 into the passage 60.
Once the second ingredient 22 begins flowing into the first chamber 14, the user can agitate the mixture of the first and second ingredients 16, 22 by grasping the handle member 64 and moving the mixing device 44 up and down along the axis X and/or rotating the mixing device 44 about the axis X. The legs 46 and the heads 50 of the mixing device 44 facilitate mixing of the first and second ingredients 16, 22. In some embodiments, once the first and second ingredients 16, 22 are mixed, a reaction occurs to form the bone cement 90 (FIG. 4).
Once the first and second ingredients 16, 22 are sufficiently mixed (e.g., into a homogeneous mixture) the user grasps the handle member 64 and moves the handle member 64, the extension member 52, and the mixing device 44 upward along the axis X toward the first end 28 of the tube 26. In some embodiments, the opening device 24 is detachably supported by the piston 36 such that the opening device 24 remains frictionally attached to the second member 18 once the piercing member 72 pierces the sealing member 68, and movement of the second member 18 toward the first end 28 of the tube 26 pulls the opening device 24 toward the first end 28 of the tube 26 (FIG. 4).
Continued operation of the vacuum source 40 draws the piston 36 upward along the axis X toward the first end 28 of the tube 26 and also draws out air bubbles within the bone cement 90. It will be appreciated that this movement of the piston 36 substantially eliminates open space between the piston 36 and the cap 32 and substantially gathers the bone cement 90 therebetween. In some embodiments, the piston 36 moves selectively away from the second end 30. For instance, the piston 36 and the tube 26 can include corresponding locking tabs. The locking tabs retain the piston 36 in position adjacent the second end 30. Then, when the user so chooses, the piston 36 can turn the piston 36 about the axis X to unlock the corresponding locking tabs and allow the piston 36 to move toward the first end 28 of the tube 26.
Then, once the vacuum 40 is removed, the extension member 52 can be broken just above the cap 32, and the filter device 80 can be removed from the port 38. Subsequently, the dispensing tube 42 can be threaded to the port 38, and the container 10 can be loaded into a dispensing device, such as a bone cementing gun (not specifically shown) for dispensing the bone cement 90 to the intended area. It will be appreciated that the opening device 24 substantially seals the passage 60 such that the bone cement 90 is unlikely to flow out of the first chamber 14 through the passage 60. It will also be appreciated that the width of the base 70 is such that the bone cement 90 is able to bypass the base 70 and flow out of the first chamber 14 through the port 38.
Referring now to FIG. 5, a container 110 is illustrated according to various other embodiments of the present disclosure. Features that are similar to those of the container 10 of FIGS. 1-4 are identified with similar reference numerals increased by 100.
As shown in FIG. 5, the container 110 includes an opening device 124 wherein the piercing member 172 remains attached to the piston 136. As shown, the piercing member 172 has a length sufficient enough to extend from the piston 136 and into the aperture 162 to substantially plug the aperture 162. For example, the length of the piercing member 172 is approximately two centimeters in some embodiments. Because the piercing member 172 substantially plugs the aperture 162, the bone cement 190 is unlikely to backflow into the passage 160. Also, the bone cement 190 is less likely to be contaminated.
Referring now to FIG. 6, a container 210 is illustrated according to various other embodiments of the present disclosure. Features that are similar to those of the container 10 of FIG. 1-4 are identified with similar reference numerals increased by 200.
As shown in FIG. 6, the container 210 includes a first member 212 and a second member 218. The second member 218 includes a handle member 264 and an extension member 252. The second chamber 220 is defined substantially within only the extension member 252. It will be appreciated that the extension member 252 can be of any suitable width, diameter, length, or other dimension so as to encapsulate a predetermined amount of the second ingredient 222.
By depressing the handle member 264 and moving the extension member 252 toward the opening device 224, the piercing member 272 pierces the sealing member 268. This unseals the aperture 262 in the extension member 252, thereby allowing the second ingredient 222 to flow out from the second chamber 220 and into the first chamber 214 to mix with the first ingredient 216. It will be appreciated that the container 210 can be simpler to manufacture because the second chamber 220 is defined substantially within only the extension member 252.
In summary, the container 10 allows for convenient manufacture of bone cement 90 because the first and second ingredients 16, 22 can be pre-measured and disposed within the first and second chambers 14, 20, respectively and because mixing the ingredients 16, 22 can be performed with relatively few steps. Also, the first and second ingredients 16, 22 can be mixed substantially without exposing the user to harmful vapors because the mixing can be performed under vacuum. Moreover, the sterility of the ingredients 16, 22 and ultimately the bone cement 90 can be ensured using the container 10. Furthermore, the container 10 is relatively compact for additional convenience.
Moreover, the foregoing discussion discloses and describes merely exemplary embodiments of the present disclosure. One skilled in the art will readily recognize from such discussion, and from the accompanying drawings and claims, that various changes, modifications and variations may be made therein without departing from the spirit and scope of the disclosure as defined in the following claims.

Claims (10)

What is claimed is:
1. A method of producing bone cement in a container having a first member that defines a first chamber, a second member movably coupled to the first member, and an opening device, the second member including a mixing device movably disposed within the first chamber, the method comprising:
moving the second member of the container relative to the first member to move the mixing device in the first chamber;
selectively opening a second chamber defined in the second member with the opening device to allow a second ingredient in the second chamber to enter the first chamber;
applying a vacuum to a port in the first member to provide suction to the first chamber and suck the second ingredient from the second chamber into the first chamber;
mixing the second ingredient with a first ingredient in the first chamber by moving the mixing device in the first chamber; and
after mixing, dispensing the bone cement through the port.
2. The method of claim 1, wherein selectively opening the second chamber comprises selectively piercing a sealing member that seals the second chamber.
3. The method of claim 2, further comprising substantially plugging the second chamber.
4. The method of claim 1, further comprising coupling the first chamber to a vacuum source.
5. The method of claim 1, further comprising coupling a dispensing tube to the port of the first member such that the first chamber is in communication with the dispensing tube.
6. The method of claim 1, further comprising removing a guard member that selectively limits movement of a sealing member that seals the second chamber toward the opening device.
7. A method of producing bone cement in a container having a first member that defines a first chamber, a second member movably coupled to the first member, and a combined piercing/resealing member, the second member defining a second chamber and including a mixing device movably disposed within the first chamber, the method comprising:
moving the second member of the container relative to the first member to move the mixing device in the first chamber;
selectively piercing a sealing member positioned between the first and second chambers with the combined piercing/resealing member to provide an opening in the sealing member allowing a second ingredient in the second chamber to enter the first chamber; and
mixing the second ingredient with a first ingredient in the first chamber by moving the mixing device in the first chamber;
resealing the opening in the sealing member with the combined piercing/resealing member.
8. The method of claim 7, further comprising coupling the first chamber to a vacuum source.
9. The method of claim 7, further comprising coupling a dispensing tube to a port of the first member such that the first chamber is in communication with the dispensing tube.
10. The method of claim 7, further comprising removing a guard member that selectively limits movement of a sealing member that seals the second chamber toward the opening device.
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US14/201,105 US9492947B2 (en) 2008-08-22 2014-03-07 Bone cement mixing cartridge and method of use
US15/193,391 US9974589B2 (en) 2008-08-22 2016-06-27 Bone cement mixing cartridge and method of use
US15/985,462 US10478242B2 (en) 2008-08-22 2018-05-21 Bone cement mixing cartridge and method of use
US16/686,979 US10959764B2 (en) 2008-08-22 2019-11-18 Bone cement mixing cartridge and method of use

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US14/201,105 Active US9492947B2 (en) 2008-08-22 2014-03-07 Bone cement mixing cartridge and method of use
US15/193,391 Active US9974589B2 (en) 2008-08-22 2016-06-27 Bone cement mixing cartridge and method of use
US15/985,462 Active US10478242B2 (en) 2008-08-22 2018-05-21 Bone cement mixing cartridge and method of use
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US15/985,462 Active US10478242B2 (en) 2008-08-22 2018-05-21 Bone cement mixing cartridge and method of use
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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9492947B2 (en) 2008-08-22 2016-11-15 Encore Medical, L.P. Bone cement mixing cartridge and method of use
US9776150B2 (en) 2013-03-06 2017-10-03 Orthovita, Inc. Mixing system and valve assembly

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8206143B2 (en) * 2007-12-13 2012-06-26 Biomet Manufacturing Corp. Modular articulating cement spacer
DE102009013211B4 (en) * 2009-03-17 2012-04-19 Aap Biomaterials Gmbh Bone cement vacuum mixing device and method for mixing bone cement
DE102010004342B4 (en) * 2010-01-11 2018-07-05 App Biomaterials Gmbh Bone cement mixing device and method for mixing bone cement
DE102011112516B4 (en) 2011-09-07 2024-02-29 Stryker European Operations Holdings Llc Container with a container for holding a liquid and a liquid removal device
DE102012024710A1 (en) * 2012-11-07 2014-05-08 Heraeus Medical Gmbh Device for mixing and discharging a pasty mass
GB2514535A (en) * 2013-03-18 2014-12-03 Summit Medical Ltd An apparatus for mixing and delivering bone cement
DE102013011295A1 (en) * 2013-07-08 2015-01-08 Heraeus Medical Gmbh Device for storing and mixing bone cement
US9549770B2 (en) * 2013-10-10 2017-01-24 Biomet Sas Vacuum indicator system that avoid release without the proper vacuum level
DE102013226118B3 (en) * 2013-12-16 2015-06-11 Heraeus Medical Gmbh Device for storing and mixing bone cement
CN105311996B (en) * 2014-06-10 2019-10-25 海尔集团技术研发中心 A kind of solvent mixing arrangement and washing machine
IL242924A0 (en) * 2015-12-03 2016-04-21 Omrix Biopharmaceuticals Ltd Syringe assembly for storing and mixing two components
US11980858B2 (en) 2018-11-22 2024-05-14 Capsulab Ltd Capsule, device and method for mixing multiple substances
CN110801276B (en) * 2019-10-31 2021-01-19 西安交通大学 Stirring type bone cement injector and bone cement stirring injection method
USD934445S1 (en) 2019-11-22 2021-10-26 Diyacare Ltd Device for mixing multiple substances
USD934444S1 (en) 2019-11-22 2021-10-26 Diyacare Ltd Capsules for mixing multiple substances
US11241330B1 (en) 2021-04-02 2022-02-08 Brixton Biosciences, Inc. Apparatus for creation of injectable slurry
WO2023141664A2 (en) * 2022-01-06 2023-07-27 Sunil Mehta A single-use system and method for continuous homogenization or lysis
USD1036998S1 (en) 2022-02-16 2024-07-30 Capsulab Ltd Capsule for mixing multiple substances

Citations (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3102536A (en) 1960-12-07 1963-09-03 Robert M Rose Hip prosthesis
US3144966A (en) * 1962-04-16 1964-08-18 Semco Res Inc Cartridge for mixing and dispensing sealant compound
EP0166724A1 (en) 1982-10-18 1986-01-08 Soft Sheen Products Inc Composition for treating pediculosis.
WO1987005492A1 (en) 1986-03-21 1987-09-24 Klaus Draenert Device and process for mixing and filling with bone cement
US4721390A (en) 1984-10-19 1988-01-26 Mit Ab Method for producing bone cement for fixing prostheses and device for carrying out said method
US5108452A (en) 1989-02-08 1992-04-28 Smith & Nephew Richards Inc. Modular hip prosthesis
US5328262A (en) 1992-02-07 1994-07-12 Mit Ab Method for producing reduced porosity bone cement
US5370221A (en) 1993-01-29 1994-12-06 Biomet, Inc. Flexible package for bone cement components
WO1998051240A1 (en) 1997-05-15 1998-11-19 Hayes Medical, Inc. Temporary implantable prosthesis
US5858020A (en) 1995-12-05 1999-01-12 Metagen, Llc Modular prosthesis
US5951160A (en) 1997-11-20 1999-09-14 Biomet, Inc. Method and apparatus for packaging, mixing and delivering bone cement
EP1005900A2 (en) 1995-11-13 2000-06-07 Cemvac System Aktiebolag Method and device for introducing a liquid component for bone cement into a mixing vessel
US6155812A (en) 1998-07-15 2000-12-05 Biomet, Inc Cement mold for a temporary implant
US6286670B1 (en) 2000-03-14 2001-09-11 Biomet, Inc. Method and apparatus for mixing a compound utilizing a gas permeable barrier
US6361731B1 (en) 1998-07-15 2002-03-26 Biomet, Inc. Method of forming a temporary implant
US20030065398A1 (en) 2001-09-14 2003-04-03 Benoist Girard Sas Resilient thimble for ball head of prosthetic joint
US20030155381A1 (en) 1996-02-21 2003-08-21 Kwan-Ho Chan System and method for mixing bone cement
US20050004680A1 (en) 2003-07-03 2005-01-06 Joseph Saladino Femoral head assembly with variable offset
US20050143828A1 (en) 2003-12-31 2005-06-30 Collins Michael S. Sleeve and method for use with modular orthopaedic implants
US7018089B2 (en) * 2002-09-17 2006-03-28 Kyphon Inc. Apparatus and methods for mixing two components
US20060109737A1 (en) 2004-11-24 2006-05-25 Biomet Cementing Technologies Ab Device for producing bone cement and method in connection therewith
US7073936B1 (en) * 1993-05-10 2006-07-11 Cemvac System Ab Method and device for feeding components for bone cement into a mixing vessel
US20070016215A1 (en) 2005-07-05 2007-01-18 Biomet Cementing Technologies Ab Method and device for bringing a powder and a liquid component, preferably polymer and monomer, in contact with each other for mixing thereof, preferably to form bone cement
FR2898039A1 (en) 2006-03-03 2007-09-07 Ceravic Sas Soc Par Actions Si PROVISIONAL IMPLANT COMPRISING TWO ASSETS.
US20070222114A1 (en) 2006-03-23 2007-09-27 Ziran Bruce H Method of forming a temporary implant and mold assembly for same
US20090175978A1 (en) 2007-12-13 2009-07-09 Biomet Manufacturing Corp. Modular Articulating Cement Spacer
US7637729B2 (en) 2007-12-13 2009-12-29 Biomet Manufacturing Corp. Modular articulating cement spacer mold

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1211426A (en) * 1916-07-25 1917-01-09 Richard J Anderson Farrington Cocktail-mixer.
US2527992A (en) * 1947-11-21 1950-10-31 Alvin A Greenberg Capsule
US2954144A (en) * 1957-10-17 1960-09-27 Hiller Aircraft Corp Storage, mixing and dispensing device
EP0290433B1 (en) * 1986-11-19 1990-09-19 Laboratorium Für Experimentelle Chirurgie Forschungsinstitut Davos Method and apparatus for preparing a self-curing two-component powder liquid bone cement
WO1999037256A1 (en) * 1998-01-21 1999-07-29 Immedica Bone cement mixer and dispenser
US6709149B1 (en) * 1998-12-14 2004-03-23 Ao Research Institute Davos Method of bone cement preparation
US6789693B2 (en) 2001-07-06 2004-09-14 Milton Lassiter Two-liter cooler
DE602004006442T2 (en) * 2003-12-01 2008-01-10 Broockeville Corp. N.V., Willemstad TWO-COMPONENT MIXING AND OUTPUT DEVICE
US8480289B2 (en) 2008-08-22 2013-07-09 Biomet Manufacturing, Llc Bone cement mixing cartridge and method of use
KR102228856B1 (en) 2014-03-20 2021-03-17 엘지전자 주식회사 Mobile terminal and method for controlling the same

Patent Citations (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3102536A (en) 1960-12-07 1963-09-03 Robert M Rose Hip prosthesis
US3144966A (en) * 1962-04-16 1964-08-18 Semco Res Inc Cartridge for mixing and dispensing sealant compound
EP0166724A1 (en) 1982-10-18 1986-01-08 Soft Sheen Products Inc Composition for treating pediculosis.
US4721390A (en) 1984-10-19 1988-01-26 Mit Ab Method for producing bone cement for fixing prostheses and device for carrying out said method
WO1987005492A1 (en) 1986-03-21 1987-09-24 Klaus Draenert Device and process for mixing and filling with bone cement
US5015101A (en) 1986-03-21 1991-05-14 Klaus Draenert Apparatus and process for mixing and filling
US5108452A (en) 1989-02-08 1992-04-28 Smith & Nephew Richards Inc. Modular hip prosthesis
US5501520A (en) 1992-02-07 1996-03-26 Mit Ab Device for producing reduced porosity bone cement
US5328262A (en) 1992-02-07 1994-07-12 Mit Ab Method for producing reduced porosity bone cement
US5370221A (en) 1993-01-29 1994-12-06 Biomet, Inc. Flexible package for bone cement components
US7073936B1 (en) * 1993-05-10 2006-07-11 Cemvac System Ab Method and device for feeding components for bone cement into a mixing vessel
EP1005900A2 (en) 1995-11-13 2000-06-07 Cemvac System Aktiebolag Method and device for introducing a liquid component for bone cement into a mixing vessel
US5858020A (en) 1995-12-05 1999-01-12 Metagen, Llc Modular prosthesis
US20030155381A1 (en) 1996-02-21 2003-08-21 Kwan-Ho Chan System and method for mixing bone cement
WO1998051240A1 (en) 1997-05-15 1998-11-19 Hayes Medical, Inc. Temporary implantable prosthesis
US5951160A (en) 1997-11-20 1999-09-14 Biomet, Inc. Method and apparatus for packaging, mixing and delivering bone cement
US6155812A (en) 1998-07-15 2000-12-05 Biomet, Inc Cement mold for a temporary implant
US6361731B1 (en) 1998-07-15 2002-03-26 Biomet, Inc. Method of forming a temporary implant
US6286670B1 (en) 2000-03-14 2001-09-11 Biomet, Inc. Method and apparatus for mixing a compound utilizing a gas permeable barrier
US20050027302A1 (en) 2001-09-14 2005-02-03 Benoist Girard Sas Resilient thimble for ball head of prosthetic joint
US20030065398A1 (en) 2001-09-14 2003-04-03 Benoist Girard Sas Resilient thimble for ball head of prosthetic joint
US7018089B2 (en) * 2002-09-17 2006-03-28 Kyphon Inc. Apparatus and methods for mixing two components
US20050004680A1 (en) 2003-07-03 2005-01-06 Joseph Saladino Femoral head assembly with variable offset
US20050143828A1 (en) 2003-12-31 2005-06-30 Collins Michael S. Sleeve and method for use with modular orthopaedic implants
US20060109737A1 (en) 2004-11-24 2006-05-25 Biomet Cementing Technologies Ab Device for producing bone cement and method in connection therewith
US20070016215A1 (en) 2005-07-05 2007-01-18 Biomet Cementing Technologies Ab Method and device for bringing a powder and a liquid component, preferably polymer and monomer, in contact with each other for mixing thereof, preferably to form bone cement
FR2898039A1 (en) 2006-03-03 2007-09-07 Ceravic Sas Soc Par Actions Si PROVISIONAL IMPLANT COMPRISING TWO ASSETS.
US20070222114A1 (en) 2006-03-23 2007-09-27 Ziran Bruce H Method of forming a temporary implant and mold assembly for same
US20090175978A1 (en) 2007-12-13 2009-07-09 Biomet Manufacturing Corp. Modular Articulating Cement Spacer
US7637729B2 (en) 2007-12-13 2009-12-29 Biomet Manufacturing Corp. Modular articulating cement spacer mold

Non-Patent Citations (11)

* Cited by examiner, † Cited by third party
Title
Biomet Orthopedics, Inc., "The Optivac® Vacuum Mixing System, Intelligent Simplicity," brochure, 2000 (12 pages).
Biomet, "Mixing and Delivery: Optivac®", pp. 1-2, available at http://www.bonecement.com/index.php?id=16933, printed Jul. 15, 2008.
Biomet, "Optivac® Procedure Set," pp. 1-2, available at http://www.bonecement.com/index.php?id=17149, last visited Jul. 15, 2008.
Biomet, Inc., "Optivac® Fusion(TM) Vacuum Mixing Bowl," pp. 1-2, 2001-2008, available at http://www.biomet.com/hcp/prodpage.cfm?c=0F&p=090505 (printed Feb. 4, 2008).
Biomet, Inc., "Optivac® Fusion™ Vacuum Mixing Bowl," pp. 1-2, 2001-2008, available at http://www.biomet.com/hcp/prodpage.cfm?c=0F&p=090505 (printed Feb. 4, 2008).
Biomet, Inc., "Optivac® Vacuum Mixing System," 2001-2008, pp. 1-2, available at http://www.biomet.com/hcp/prodpage.cfm?c=0F&p=0A0403 (printed Feb. 4, 2008).
DePuy Orthopaedics, Inc., "Prostalac Hip Temporary Prosthesis", pp. 1-2, 2001, available at http:/www.fda.gov/cdrh/mda/docs/h000004.html, printed Feb. 8, 2007 (2 pages).
DePuy, "Prostalac® Hip", pp. 1-2, 2005-2006, available at http://www.jnjgateway.com/home.jhtml?page=viewContent&contentId=09008b98800540d1&loc=USENG, printed Feb. 8, 2007 (2 pages).
Exactech, Inc., "InterSpace® Hip," p. 1, available at http://www.exac.com/products/cement-spacers/interspace-hip, last visited Jul. 15, 2008.
International Search Report and Written Opinion for PCT/US2008/085529 mailed Mar. 17, 2009 claiming priority to U.S. Appl. No. 11/955,601, filed Dec. 13, 2007.
Johnson & Johnson, "Prostalac® Hip Essential Product Information," p. 1-3, available at http://www.jnjgateway.com/home.jhtml?contentID=09008b9880054123&loc=USENG&page=viewContent, last visited Jul. 15, 2008.

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9492947B2 (en) 2008-08-22 2016-11-15 Encore Medical, L.P. Bone cement mixing cartridge and method of use
US9974589B2 (en) 2008-08-22 2018-05-22 Encore Medical, L.P. Bone cement mixing cartridge and method of use
US10478242B2 (en) 2008-08-22 2019-11-19 Encore Medical, L.P. Bone cement mixing cartridge and method of use
US10959764B2 (en) 2008-08-22 2021-03-30 Encore Medical, L.P. Bone cement mixing cartridge and method of use
US9776150B2 (en) 2013-03-06 2017-10-03 Orthovita, Inc. Mixing system and valve assembly
US10143982B2 (en) 2013-03-06 2018-12-04 Orthovita, Inc. Mixing system and valve assembly

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US10959764B2 (en) 2021-03-30
US20200155214A1 (en) 2020-05-21
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US20130247516A1 (en) 2013-09-26
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US20160374741A1 (en) 2016-12-29
US9974589B2 (en) 2018-05-22
US9492947B2 (en) 2016-11-15
US20140185405A1 (en) 2014-07-03
US10478242B2 (en) 2019-11-19

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