US8408201B2 - Fluid product dispensing device - Google Patents
Fluid product dispensing device Download PDFInfo
- Publication number
- US8408201B2 US8408201B2 US12/517,912 US51791207A US8408201B2 US 8408201 B2 US8408201 B2 US 8408201B2 US 51791207 A US51791207 A US 51791207A US 8408201 B2 US8408201 B2 US 8408201B2
- Authority
- US
- United States
- Prior art keywords
- strip
- reservoir
- housing
- walls
- pivot
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active, expires
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
- A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0001—Details of inhalators; Constructional features thereof
- A61M15/0005—Details of inhalators; Constructional features thereof with means for agitating the medicament
- A61M15/0006—Details of inhalators; Constructional features thereof with means for agitating the medicament using rotating means
- A61M15/0008—Details of inhalators; Constructional features thereof with means for agitating the medicament using rotating means rotating by airflow
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
- A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
- A61M15/0033—Details of the piercing or cutting means
- A61M15/0035—Piercing means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
- A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
- A61M15/0046—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier
- A61M15/0051—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier the dosages being arranged on a tape, e.g. strips
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0091—Inhalators mechanically breath-triggered
- A61M15/0096—Hindering inhalation before activation of the dispenser
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0091—Inhalators mechanically breath-triggered
Definitions
- the present invention relates to a fluid dispenser device, and more particularly to a dry-powder inhaler.
- Inhalers are well known in the prior art. Various types exist.
- a first type of inhaler contains a reservoir receiving many doses of powder, the inhaler being provided with metering means making it possible, on each actuation, to remove one dose of said powder from the reservoir, so as to bring said dose into an expulsion duct in order to be dispensed to the user.
- Inhalers including individual reservoirs, such as capsules, that are loaded into the inhaler just before said inhaler is used are also described in the prior art.
- the advantage of such devices is that it is not necessary to store all of the doses inside the appliance, such that said appliance can be compact.
- the inhaler is more difficult to use, since the user is obliged to load a capsule into the inhaler before each use.
- Another type of inhaler consists in packaging the doses of powder in individual predosed reservoirs, then in opening one of the reservoirs each time the inhaler is actuated. That implementation seals the powder more effectively since each dose is opened only when it is about to be expelled.
- various techniques have already been proposed, such as an elongate blister strip or blisters disposed on a rotary circular disk. All existing types of inhalers, including those described above, present both advantages and drawbacks associated with their structures and with their types of operation. Thus, with certain inhalers, there is the problem of accuracy and of reproducibility for the dose on each actuation. In addition, the effectiveness of the dispensing, i.e.
- An object of the present invention is to provide a fluid dispenser device, in particular a dry-powder inhaler, that does not have the above-mentioned drawbacks.
- an object of the present invention is to provide such an inhaler that is simple and inexpensive to manufacture and to assemble, that is reliable in use, guaranteeing metering accuracy and metering reproducibility on each actuation, providing an optimum yield with regard to the effectiveness of the treatment, by making it possible to dispense a substantial fraction of the dose to the zones to be treated, in particular the lungs, avoiding, in safe and effective manner, any risk of overdosing, and that is as compact as possible, while guaranteeing sealing and absolute integrity of all of the doses up to their expulsion.
- Another object of the present invention is to provide such an inhaler including a blister strip, in which the risk of the blister strip blocking is minimized.
- Another object of the present invention is to provide such an inhaler including a blister strip, in which storage of the strip portion including the empty reservoirs is improved.
- the present invention thus provides a fluid dispenser device including a body that is provided with a dispenser orifice, said body containing a plurality of reservoirs formed on a common substrate formed by an elongate strip that includes a leading end and a trailing end, the device further including reservoir-opening means that are adapted to open a respective reservoir each time the device is actuated, and drive means for driving the elongate strip, so as to bring a full reservoir into register with said opening means before and/or during and/or after each actuation of the device, the device including at least one movable wall that separates, at least in part, a storage housing for storing the elongate strip from a reception housing for receiving the elongate strip, said elongate strip being disposed, in particular rolled up in a roll, mainly in said storage housing before the device is used for the first time, and being displaced progressively in said reception housing each time the device is actuated, said at least one movable wall causing the volume of the storage housing to decrease
- said device includes a single movable wall that is displaceable mainly in translation.
- said wall that moves in translation presents two concave longitudinal surfaces that face the storage housing and the reception housing respectively.
- said movable wall includes two lateral slide surfaces that are adapted to slide against respective guide walls of said device.
- At least one of said lateral surfaces of the movable wall and at least one of said guide walls of the device are curved, at least in part, such that said movable wall turns a little on itself during its successive movements in translation.
- said device includes at least one movable wall that pivots.
- said device includes a single pivot wall.
- said pivot wall is concave relative to the reception housing.
- said device includes two pivot walls one of which is concave relative to the reception housing and the other one of which is concave relative to the storage housing.
- said two pivot walls slide one against the other on each pivot.
- said elongate strip is disposed in a cassette that defines said storage and reception housing and that incorporates said at least one movable wall.
- said at least one movable wall is displaced under the effect of thrust exerted thereon by the blister strip.
- said opening means comprise a needle that does not move relative to the body, a reservoir being displaced against said needle each time the device is actuated, said needle penetrating inside said reservoir so as to empty it by means of an inhalation flow.
- said opening means are actuated by the user inhaling, such that the reservoir is opened and emptied simultaneously by said inhalation flow.
- FIG. 1 is a diagrammatic section view showing a dispenser device constituting an advantageous embodiment, at the beginning of use of the device;
- FIG. 2 is a view similar to the view in FIG. 1 , at the end of use of the device;
- FIGS. 3 and 4 are diagrammatic section views of a dispenser device constituting another advantageous embodiment of the invention, respectively at the beginning and at the end of use of the device;
- FIGS. 5 and 6 are diagrammatic section views of a dispenser device constituting yet another advantageous embodiment of the invention, respectively at the beginning and at the end of use of the device.
- FIGS. 1 and 2 show a first advantageous embodiment of a dry-powder inhaler.
- the inhaler includes a body 10 on which there can be slidably mounted one or two cover-forming portions (not shown) that are adapted to be opened so as to open and prime the device.
- the body 10 can be of approximately rounded shape as shown in the figures, but it could have any other appropriate shape.
- the body 10 includes a mouthpiece or inhaler endpiece 1 that defines a dispenser orifice through which the user inhales while the device is being actuated.
- the cover can open by pivoting about a common pivot axis, but any other means of opening the device can be envisaged.
- the device contains a plurality of individual reservoirs 21 , also known as blisters, that are disposed on a common substrate formed by an elongate strip 20 on which the blisters 21 are disposed one behind the other in known manner, the strip including a leading end 25 and a trailing end 28 .
- the blisters 21 are not shown along the entire strip 20 , so as to simplify the drawing for the purpose of clarity.
- the blister strip 20 is advantageously constituted by a base layer or wall that forms the cavities 21 that receive the doses of powder, and by a closure layer or wall that closes each of said blisters 21 in leaktight manner.
- the blister strip 20 is rolled-up inside the body 10 , preferably in a storage housing 11 , and strip drive means 40 are provided for progressively unrolling the blister strip and for bringing an individual reservoir or respective blister 21 into a dispensing position each time the device is actuated.
- the strip portion 25 including the empty reservoirs is adapted to be rolled up in another location of said body 10 , preferably a reception housing 15 , as described in greater detail below.
- the inhaler includes reservoir-opening means comprising a perforator system 30 for perforating the closure layer of the blisters.
- the reservoir-opening means advantageously comprise a perforator element or a needle that preferably does not move relative to the body 10 , and against which a respective blister 21 is displaced on each actuation.
- the blister 21 is thus perforated by said needle that penetrates into said blister so as to expel the powder by means of the user inhaling.
- Displacement means 40 are also provided in the device and are adapted to displace the blister strip 20 before and/or during and/or after each actuation of the device.
- the displacement means 40 are also adapted to displace the reservoir 21 to be emptied against said perforator system 30 during actuation.
- the displacement means 40 can be urged by a resilient element, such as a spring or any other equivalent resilient element, said resilient element possibly being preprimed while the device is being opened.
- the displacement means 40 preferably comprise an indexer wheel 40 that receives and guides the blisters. Turning the wheel 40 causes the blister strip 20 to advance. In a particular angular position, a given reservoir 21 is always in a position to be opened by the opening means 30 .
- rotary positioning means of said indexer wheel 40 can be provided for precisely determining its angular position after each turn.
- the positioning means can comprise a projection or finger having an end that co-operates elastically with notches provided around said wheel 40 .
- a complementary wheel could possibly be provided so as to held to guide and/or to drive the blister strip 20 .
- An actuation cycle of the device could be as follows. During opening of the device, the two cover-forming lateral portions are moved away from each other by pivoting about the body so as to open the device and thus prime the device. In this position, the indexer wheel 40 cannot be displaced towards the needle 30 since it is retained by appropriate blocking means 100 . It is while the user is inhaling through the mouthpiece 1 that the blocking means are unblocked, thereby causing said indexer wheel 40 to be displaced towards the needle, and thus causing a reservoir 21 to be opened.
- the reservoir 21 is displaced towards its open position so as to be opened by the needle that does not move relative to the body.
- the needle can also be movable during the stage of opening the reservoir 21 .
- the needle could be displaced towards the reservoir 21 while the reservoir 21 is displaced towards the needle.
- the reservoir 21 and the needle are displaced in the same direction during actuation, the reservoir 21 being displaced quicker in said direction, such that it comes into contact with the needle so as to be opened.
- an inhalation trigger system can be provided that advantageously comprises a unit 60 that is displaceable and/or deformable under the effect of inhalation, the unit 60 being adapted to release the blocking means 100 .
- the unit 60 advantageously comprises a deformable air chamber 61 .
- the inhalation by the user causes said deformable air chamber 61 to deform, thereby enabling said blocking means 100 to be released, and thus enabling the indexer wheel 40 and a respective reservoir 21 to be displaced towards its opening position.
- the reservoir 21 is thus opened only at the moment of inhalation, so that it is emptied simultaneously. Thus, there is no risk of any of the dose being lost between opening the reservoir and emptying it.
- inhalation trigger means could also be used, e.g. using a pivotable valve flap that, while the user is inhaling, pivots under the effect of the suction created by the inhalation, with pivoting of the valve flap causing the blocking means blocking the movable support means to be released, thereby causing the reservoir to be displaced towards the opening means.
- the inhaler further includes a dispenser chamber 70 for receiving the dose of powder after a respective reservoir 21 has been opened.
- the dispenser chamber 70 is advantageously provided with at least one bead 75 that is displaced inside said chamber 70 during inhalation so as to improve dispensing of the air and powder mixture after a reservoir 21 has been opened, in order to increase the effectiveness of the device.
- the opening system 30 in particular the needle, to be formed directly on said dispenser chamber 70 , e.g. at the end of a channel 69 leading to said chamber 70 .
- the individual reservoirs or blisters 21 are formed on an elongate strip 20 that, initially, is mainly stored in the form of a roll in a storage housing 11 inside the body 10 of the device.
- the rolled-up blister strip 20 can be held by internal walls of said storage housing 11 without its trailing end 28 (in the direction of displacement of the blister strip 20 ) being fastened relative to said body 10 , thereby making it easier to assemble the blister-strip roll inside the device.
- the blister strip 20 is displaced by the user, advantageously by means of the indexer wheel 40 that advantageously presents at least one, and preferably a plurality of recesses 41 , having a shape that corresponds to the shape of the blisters.
- the indexer wheel 40 when it turns, it advances the blister strip 20 .
- No other drive system is necessary for displacing the blister strip 20 during each actuation.
- it is possible to use other means for advancing the blister strip e.g. providing a profile on the longitudinal lateral edges of the blister strip, said profile being adapted to co-operate with appropriate drive means.
- holes formed along the lateral edges of the blister strip could also be used to cause the blister strip to advance by means of toothed wheels co-operating with said holes.
- the blister-strip portion with the empty reservoirs must be suitable for being stored in easy and compact manner in the device.
- the used blister strip is rolled-up automatically, once again forming a roll.
- the leading end 25 of the blister strip 20 can possibly roll up around a rotary or stationary receiver element (not shown).
- the reception housing 15 can include guide walls, in particular an external guide wall 16 that is curved, e.g. cylindrical, and against which the blister strip 20 slides.
- An internal guide wall 17 can also be provided at the inlet to the reception housing 15 , and preferably extends approximately parallel to the external guide wall 16 , so as to form a guide channel 18 for the blister strip 20 .
- the guide walls 16 , 17 further facilitate proper rolling up of the blister strip 20 .
- At least one movable wall is provided so as to separate the storage housing 11 from the reception housing 15 , said wall being displaced each time the device is actuated, so as to cause the volume of the reception housing 15 to increase progressively, and the volume of the storage housing 11 to decrease.
- the major portion of the blister strip 20 is initially disposed in the storage housing 11 , said storage housing is going to empty progressively, whereas the reception housing 15 is going to fill up progressively with the portion of strip supporting the empty reservoirs.
- the invention thus makes it possible to optimize the volume that is available in the body 10 .
- it is the blister strip itself that pushes said at least one movable wall, so as to displace it on each actuation.
- the device includes a cassette forming a unit containing said blister strip 20 , defining the storage and reception housings 11 , 15 , said at least one movable wall, and possibly the guide walls 16 , 17 .
- This embodiment makes it easier to assemble the blister strip 20 in the device.
- FIGS. 1 and 2 show a first embodiment of the invention, in which the device includes a single movable wall 500 that is displaceable mainly in translation.
- the wall 500 that moves in translation advantageously includes two rounded or concave surfaces 501 , 502 facing the storage housing 11 and the reception housing 15 respectively, so as to adapt to the blister strip 20 being rolled up.
- Lateral slide surfaces 503 , 504 of the movable wall 500 are advantageously adapted to slide against respective complementary guide walls 553 , 554 .
- one or both guide walls 553 , 554 can be curved a little, as shown in FIGS. 1 and 2 , thereby causing the movable wall 500 to turn a little about its own axis while it is moving in translation. This makes it possible to optimize still further the volume that is available for the blister strip 20 .
- FIGS. 3 and 4 show a second embodiment of the invention in which there is a single movable pivot wall 600 that is advantageously rounded or concave relative to the reception housing 15 so as to adapt to the blister strip 20 being rolled up.
- the pivot wall 600 can pivot about a pivot point 610 that can be formed by a fold zone, as shown in FIGS. 3 and 4 .
- FIGS. 5 and 6 show another variant with two pivot walls 600 , 601 .
- a second movable wall 601 is provided that is concave relative to the storage housing 11 , the two walls 600 , 601 sliding one on the other via their respective outside surfaces.
- each pivot wall 600 , 601 can pivot about two pivot points 610 & 610 ′ and 620 & 620 ′ respectively.
- the two pivot points can be separated by a flexible connection piece, as shown in FIGS. 5 and 6 . This enables the walls to pivot more easily, and makes it possible to optimize the available space.
- the present invention therefore makes it possible to provide a dry-powder inhaler that performs the following functions in particular:
- the various functions are also provided by the device of the invention as described above. It should be observed that the various functions, even if they are shown as being provided simultaneously on the various embodiments of the inhaler, could be implemented separately.
- the inhalation trigger mechanism could be used independently of the type of reservoir-opening means, independently of the use of a dose indicator, independently of the way in which the individual reservoirs are arranged relative to one another, etc.
- the prepriming means and the inhalation trigger system could be made in some other way. The same applies for other component parts of the device.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR06/55406 | 2006-12-11 | ||
FR0655406 | 2006-12-11 | ||
FR0655406A FR2909641B1 (fr) | 2006-12-11 | 2006-12-11 | Dispositif de distribution de produit fluide |
PCT/FR2007/052466 WO2008078032A2 (fr) | 2006-12-11 | 2007-12-10 | Dispositif de distribution de produit fluide |
Publications (2)
Publication Number | Publication Date |
---|---|
US20100288278A1 US20100288278A1 (en) | 2010-11-18 |
US8408201B2 true US8408201B2 (en) | 2013-04-02 |
Family
ID=37999198
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US12/517,912 Active 2030-07-02 US8408201B2 (en) | 2006-12-11 | 2007-12-10 | Fluid product dispensing device |
Country Status (6)
Country | Link |
---|---|
US (1) | US8408201B2 (fr) |
EP (1) | EP2101849B1 (fr) |
JP (1) | JP5028493B2 (fr) |
CN (1) | CN101557852B (fr) |
FR (1) | FR2909641B1 (fr) |
WO (1) | WO2008078032A2 (fr) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20110114088A1 (en) * | 2008-01-24 | 2011-05-19 | Stephen William Eason | Inhaler |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2904229B1 (fr) * | 2006-07-25 | 2008-10-10 | Valois Sas | Dispositif de distribution de produit fluide. |
EP2082767A1 (fr) * | 2008-01-24 | 2009-07-29 | Vectura Delivery Devices Limited | Inhalateur |
FR2933619B1 (fr) * | 2008-07-11 | 2012-03-30 | Valois Sas | Dispositif d'inhalation de poudre |
FR2936424B1 (fr) * | 2008-09-30 | 2012-01-20 | Valois Sas | Dispositif d'inhalation de poudre. |
FR2936425B1 (fr) * | 2008-09-30 | 2012-02-17 | Valois Sas | Dispositif d'inhalation de poudre. |
US8763608B2 (en) | 2008-10-09 | 2014-07-01 | Vectura Delivery Devices Limited | Inhaler |
GB201020130D0 (en) | 2010-11-26 | 2011-01-12 | Vectura Delivery Devices Ltd | Inhaler |
EP2198908A1 (fr) * | 2008-12-19 | 2010-06-23 | Boehringer Ingelheim International Gmbh | Inhalateur |
DE102012104850A1 (de) * | 2012-04-05 | 2013-10-10 | Alfred Von Schuckmann | Vorrichtung zur portionierten Ausgabe von Medikamenten |
EP3052169B1 (fr) * | 2013-10-01 | 2018-07-18 | Novartis AG | Dispositif d'inhalateur à piste de bande alvéolaire comportant un circuit d'extrémité séparé |
US10953165B2 (en) * | 2015-07-20 | 2021-03-23 | Vectura Delivery Devices Limited | Dry powder inhaler |
EP3725350B1 (fr) * | 2016-12-06 | 2022-02-09 | Norton (Waterford) Limited | Dispositif d'inhalation comportant un module électronique intégré |
US20220040420A1 (en) * | 2018-09-17 | 2022-02-10 | Vectura Delivery Devices Limited | Dry powder inhaler |
Citations (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2001026720A1 (fr) | 1999-10-12 | 2001-04-19 | Shl Medical Ab | Inhalateur |
WO2002036189A1 (fr) | 2000-10-31 | 2002-05-10 | Glaxo Group Limited | Distributeur de médicaments |
WO2003061743A1 (fr) | 2002-01-25 | 2003-07-31 | Glaxo Group Limited | Distributeur de medicament |
US20040244794A1 (en) * | 2001-08-09 | 2004-12-09 | Richards David Hugh | Inhalation device with a pharmaceutical composition |
US20050005934A1 (en) * | 2001-10-19 | 2005-01-13 | Harvey Stephen James | Medicament dispenser |
US20050081853A1 (en) * | 2000-02-01 | 2005-04-21 | Valois S.A.S. | Breath actuated dry powder inhaler and tape dose strip |
US20060196504A1 (en) * | 2003-07-24 | 2006-09-07 | Stephen Augustyn | Medicament dispenser |
US20070062525A1 (en) * | 2002-01-25 | 2007-03-22 | Bonney Stanley G | Medicament dispenser |
US20110073106A1 (en) * | 2003-09-15 | 2011-03-31 | Vectura Delivery Devices Limited | Dry powder inhaler |
US20110132358A1 (en) * | 2003-10-17 | 2011-06-09 | Vectura Delivery Devices Limited | Inhaler |
-
2006
- 2006-12-11 FR FR0655406A patent/FR2909641B1/fr active Active
-
2007
- 2007-12-10 WO PCT/FR2007/052466 patent/WO2008078032A2/fr active Search and Examination
- 2007-12-10 US US12/517,912 patent/US8408201B2/en active Active
- 2007-12-10 EP EP07871898.8A patent/EP2101849B1/fr active Active
- 2007-12-10 CN CN2007800457566A patent/CN101557852B/zh not_active Expired - Fee Related
- 2007-12-10 JP JP2009540824A patent/JP5028493B2/ja not_active Expired - Fee Related
Patent Citations (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2001026720A1 (fr) | 1999-10-12 | 2001-04-19 | Shl Medical Ab | Inhalateur |
US20050081853A1 (en) * | 2000-02-01 | 2005-04-21 | Valois S.A.S. | Breath actuated dry powder inhaler and tape dose strip |
WO2002036189A1 (fr) | 2000-10-31 | 2002-05-10 | Glaxo Group Limited | Distributeur de médicaments |
US6880722B2 (en) * | 2000-10-31 | 2005-04-19 | Glaxo Group Limited | Medicament dispenser |
US20040244794A1 (en) * | 2001-08-09 | 2004-12-09 | Richards David Hugh | Inhalation device with a pharmaceutical composition |
US20050005934A1 (en) * | 2001-10-19 | 2005-01-13 | Harvey Stephen James | Medicament dispenser |
WO2003061743A1 (fr) | 2002-01-25 | 2003-07-31 | Glaxo Group Limited | Distributeur de medicament |
US20070062525A1 (en) * | 2002-01-25 | 2007-03-22 | Bonney Stanley G | Medicament dispenser |
US20060196504A1 (en) * | 2003-07-24 | 2006-09-07 | Stephen Augustyn | Medicament dispenser |
US20110073106A1 (en) * | 2003-09-15 | 2011-03-31 | Vectura Delivery Devices Limited | Dry powder inhaler |
US20110132358A1 (en) * | 2003-10-17 | 2011-06-09 | Vectura Delivery Devices Limited | Inhaler |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20110114088A1 (en) * | 2008-01-24 | 2011-05-19 | Stephen William Eason | Inhaler |
US8739784B2 (en) * | 2008-01-24 | 2014-06-03 | Vectura Delivery Devices Limited | Inhaler |
Also Published As
Publication number | Publication date |
---|---|
US20100288278A1 (en) | 2010-11-18 |
FR2909641A1 (fr) | 2008-06-13 |
EP2101849B1 (fr) | 2017-09-20 |
JP5028493B2 (ja) | 2012-09-19 |
CN101557852A (zh) | 2009-10-14 |
CN101557852B (zh) | 2012-01-11 |
WO2008078032A2 (fr) | 2008-07-03 |
FR2909641B1 (fr) | 2011-03-04 |
EP2101849A2 (fr) | 2009-09-23 |
WO2008078032A3 (fr) | 2008-10-23 |
JP2010512212A (ja) | 2010-04-22 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US8408201B2 (en) | Fluid product dispensing device | |
US8225784B2 (en) | Fluid product dispensing device | |
US9872963B2 (en) | Device for dispensing a fluid product | |
US8261740B2 (en) | Fluid-product dispensing device | |
US7779839B2 (en) | Fluid product dispensing device | |
US8020554B2 (en) | Opening device for fluid product dispensing device | |
US20150114391A1 (en) | Device for dispensing a fluid product | |
US8322336B2 (en) | Fluid-product dispensing device | |
US9050426B2 (en) | Device for distributing a fluid product | |
US7878196B2 (en) | Fluid product dispensing device | |
US20100319693A1 (en) | Fluid product dispensing device | |
US10058662B2 (en) | Device for dispensing fluid product | |
US10342937B2 (en) | Fluid-product distribution device | |
US10080852B2 (en) | Fluid dispenser device with bellows | |
US20110120467A1 (en) | Powder inhalation device | |
US9981091B2 (en) | Dry powder inhalator | |
US8671939B2 (en) | Device for distributing fluid product | |
US8360055B2 (en) | Fluid-product dispensing device | |
US8757149B2 (en) | Device for dispensing a fluid product | |
US8322337B2 (en) | Fluid product dispensing device | |
US8844523B2 (en) | Device for dispensing fluid product | |
US20100018527A1 (en) | Fluid product dispensing device | |
US8739782B2 (en) | Powder inhalation device | |
US8960191B2 (en) | Powder inhalation device | |
US9889263B2 (en) | Fluid dispenser device |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
AS | Assignment |
Owner name: VALOIS SAS, FRANCE Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNORS:POCOCK, ANDREW;KAY, STUART;GREENHALGH, PAUL;AND OTHERS;REEL/FRAME:022787/0570 Effective date: 20090528 |
|
AS | Assignment |
Owner name: APTAR FRANCE SAS, FRANCE Free format text: CHANGE OF NAME;ASSIGNOR:VALOIS;REEL/FRAME:028930/0872 Effective date: 20120725 |
|
STCF | Information on status: patent grant |
Free format text: PATENTED CASE |
|
FPAY | Fee payment |
Year of fee payment: 4 |
|
MAFP | Maintenance fee payment |
Free format text: PAYMENT OF MAINTENANCE FEE, 8TH YEAR, LARGE ENTITY (ORIGINAL EVENT CODE: M1552); ENTITY STATUS OF PATENT OWNER: LARGE ENTITY Year of fee payment: 8 |