US5697948A - Device for delivering and deploying intraluminal devices - Google Patents

Device for delivering and deploying intraluminal devices Download PDF

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US5697948A
US5697948A US08/483,190 US48319095A US5697948A US 5697948 A US5697948 A US 5697948A US 48319095 A US48319095 A US 48319095A US 5697948 A US5697948 A US 5697948A
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guide sheath
sheath
catheter
intraluminal device
device
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US08/483,190
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Michael L. Marin
Ralph Marin
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Cardinal Health Switzerland 515 GmbH
Endovascular Systems Inc
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Endovascular Systems Inc
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Priority to US08/243,190 priority Critical patent/US5456694A/en
Application filed by Endovascular Systems Inc filed Critical Endovascular Systems Inc
Priority to US08/483,190 priority patent/US5697948A/en
Assigned to STENTCO, INC. reassignment STENTCO, INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: MARIN, MICHAEL, MARIN, RALPH
Priority claimed from PCT/US1996/010405 external-priority patent/WO1996039997A2/en
Assigned to ENDOVASCULAR SYSTEMS, INC. reassignment ENDOVASCULAR SYSTEMS, INC. CHANGE OF NAME (SEE DOCUMENT FOR DETAILS). Assignors: STENTCO, INC.
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Assigned to CARDINAL HEALTH SWITZERLAND 515 GmbH reassignment CARDINAL HEALTH SWITZERLAND 515 GmbH ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: CORDIS CORPORATION
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/95Instruments specially adapted for placement or removal of stents or stent-grafts
    • A61F2/958Inflatable balloons for placing stents or stent-grafts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/01Introducing, guiding, advancing, emplacing or holding catheters
    • A61M25/09Guide wires
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/04Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
    • A61F2/06Blood vessels
    • A61F2/07Stent-grafts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/01Introducing, guiding, advancing, emplacing or holding catheters
    • A61M25/09Guide wires
    • A61M2025/09008Guide wires having a balloon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/01Introducing, guiding, advancing, emplacing or holding catheters
    • A61M25/09Guide wires
    • A61M2025/09175Guide wires having specific characteristics at the distal tip
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/10Balloon catheters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/10Balloon catheters
    • A61M25/104Balloon catheters used for angioplasty

Abstract

A device for delivering and deploying an intraluminal device such as a stent. The device has a guide sheath with a movable tip element, preferably in the form of an inflatable balloon, at its distal end that facilitates insertion of the guide sheath. The intraluminal device is carried on a catheter within the sheath. The sheath may be formed from a very thin flexible material so that a smaller introducer and incision in the patient may be used. The internal pressure of the sheath may be varied to alter pushability and flexibility of the sheath. The tip element thus preferably forms a fluid tight seal with the distal end of the guide sheath. A handle is provided to hold the catheter stationary while the guide sheath is retracted to expose the intraluminal device for deployment. This minimizes the likelihood that movement of the sheath will displace the intraluminal device after it has been properly positioned.

Description

This is a continuation-in-part of U.S. patent application Ser. No. 08/243,190, now U.S. Pat. No. 5,456,694, filed May 13, 1994, entitled Device for Delivering and Deploying Intraluminal Devices.

This invention relates to a device for delivering and deploying an intraluminal device. The invention has particular utility as a device for delivering and deploying stents and endovascular grafts within a blood vessel.

An endovascular graft is placed within a blood vessel and serves as a conduit for blood flow to exclude a vascular occlusion, aneurysm or other vessel abnormity. It may be made of a variety of materials, but most commonly is made of dacron, expanded polytetrafluoroethylene (ePTFE) or human vein. It is necessary to anchor the graft within the lumen of the blood vessel and this can be accomplished by means of an intravascular stent which is also commonly used to hold open diseased or occluded arteries. There are a number of known stents; some are of the self-expanding type and some are made of a material (for example metal) which can be expanded after the stent is in place to frictionally engage the blood vessel. Palmaz U.S. Pat. No. 4,776,337 illustrates in FIGS. 2A and 2B a stent of the latter type which is currently in use. As used herein, the term "graft stent complex" is intended to include the combination of a graft and one or more stents.

The delivery and deployment systems for a graft stent complex typically includes a guide sheath (catheter) which is properly positioned within the vasculature to guide the passage of a deployment mechanism (commonly a balloon catheter supporting the graft stent complex) to the proper site. The guide sheath have a relatively large diameter resulting in difficulty passing the sheath through arteries which usually are not straight and may have many curves or twists in them. Also, arteries may contain areas of disease (atherosclerotic plaque) which may obstruct the passage of the guide sheath through the vascular tree. Irregularly shaped plaque which could accidentally engage an endoluminal catheter may create potential sites for arterial injury. Further, the vasculature may contain segments which are weaker than others, putting them at risk for perforation should they engage the guide sheath as it is being moved along the arterial wall.

The conventional technique for positioning a guide sheath within a blood vessel requires the use of a stylet (or mandrel or stiffening catheter as it is sometimes called), which includes a tapered distal end extending from the distal end of the guide sheath to enhance pushability of the guide sheath while providing a tapered distal face to ease passage of the guide sheath through the artery. The stylet, however, does not completely cover the relatively sharp edges of the guide sheath. Patients, therefore, are subject to arterial injury, and dislodgement of intraluminal thrombus and accumulated plaque on the arterial wall. This can lead to severe injury. Moreover, there is a trade-off between stiffness and flexibility. If the sheath is too stiff, movement through the artery is difficult. If it is too flexible, the sheath is difficult to push. Since the flexibility of the stylet is not adjustable, passage of the catheter through sharp turns in the vasculature can be very difficult, if not impossible. For example, the iliac artery is commonly kinked in patients with aortic aneurysm disease because of the frequent elongation of the vasculature during formation of the aneurysm. Manipulation of a wide guide sheath through such an artery using conventional techniques can be exceedingly difficult.

Also, conventional guide sheaths need to be large enough to permit ease of movement of an endovascular graft out of the sheath and into the vasculature. The sheath size has to be large enough to maintain a low coefficient of friction between the inner surface of the deployment catheter and the graft stent complex. Such large sheaths require large holes into the inserting blood vessel.

Finally, in the systems currently used for delivering a graft stent complex through a guide sheath, the balloon catheter containing the graft stent complex must be introduced through a hemostatic valve at the proximal end of the guide sheath and pushed through the entire length of the guide sheath (for example about sixty cm) to the deployment position. This can prove to be time consuming and difficult. In addition, the stent can be dislodged from the balloon while being pushed through the long guide sheath. This can result in the sharp metal stent perforating the deployment balloon. In either case, it is necessary to withdraw the balloon catheter and repeat the procedure.

FIGS. 1-9 show two devices for delivering and deploying intraluminal devices such as stents which overcome the above problems. Those devices comprise a guide sheath and a lead balloon which, when inflated, seals the guide sheath and provides a tapered leading edge for the guide sheath. In the case of patients with a tortuous vasculature, i.e. an arterial system in which the blood vessels have many twists and turns, as is often the case with elderly patients, it can be extremely difficult to push the guide sheath through the vasculature.

Thus, there exists a need for an improved process which simplifies the delivery of an intraluminal device such as a stent or graft stent complex to a position within a patient's vasculature, which process is effective even though the vasculature is tortuous.

OBJECTS OF THE INVENTION

The main object of the invention is to provide an improved device for delivering and deploying an endovascular stent and/or graft stent complex.

Another object is to provide a device for delivering and deploying a stent and/or graft stent complex which avoids or at least reduces the foregoing drawbacks of prior art stent delivery and deployment systems.

A still further object is to provide a device for delivering and deploying a stent and/or graft/stent complex in which the profile (diameter) of the device is reduced for a given size prosthesis.

SUMMARY OF THE INVENTION

According to the invention, a device for delivering and deploying a stent comprises a guide sheath and a lead balloon within the guide sheath. A catheter containing the intraluminal device to be deployed is positioned within the guide sheath. The lead balloon extends partially from the distal end of the guide sheath and, when it is inflated, provides a tapered surface at the distal end of the guide sheath which merges smoothly with the outer surface of the guide sheath, thereby reducing the likelihood of accidental arterial injury or dislodgement of thrombus or plaque. In the preferred embodiment, fluid under pressure is applied to the sheath to control the flexibility of the sheath so that the tradeoff between pushability and flexibility can be optimized for the specific conditions of the vasculature.

To deploy a stent or the like, the guide sheath must be withdrawn by first deflating the lead balloon and pulling on the guide sheath while holding the deployment catheter in position. This can cause accidental misplacement of the stent. According to a further feature of the invention, a handle is provided for retaining the proximal end of the guide sheath. The deployment catheter extends through the guide sheath and a locking valve in the end of the handle so that the handle and catheter can be locked together. The guide sheath is moveable a preselected distance within the handle so that the surgeon can retain the stent in position by holding the handle and moving the guide sheath the proper distance to expose the stent.

In accordance with a further feature of the invention, the lead balloon is mounted on a separate lead balloon catheter which can be connected in end-to-end fashion to the deployment catheter within the guide sheath. With this arrangement, the intraluminal device may be delivered by pushing on the deployment catheter and pulling on the lead balloon catheter. This is particularly beneficial in the case of a tortuous vasculature as may exist in the case of elderly patients.

In the preferred embodiment, a balloon catheter is used to deploy the stent, although mechanical deployment means or self expanding deployment means may be used as well. The stent is mounted on the deployment means which is movable with the stent to a position distal of the guide sheath when the stent is to be deployed. A single catheter shaft supporting both the deployment and lead balloons may be used, but it is also contemplated that a deployment catheter separate from the lead balloon catheter may be used. In the latter case, an opening is provided in the lead balloon catheter shaft and the distal end of the deployment catheter is inserted into the opening in such a way that a guide wire inserted into the distal end of the lead balloon catheter shaft will pass automatically into the guide wire lumen of the deployment balloon catheter.

The invention provides a number of significant advantages as compared to prior art devices for delivering and deploying a stent. First of all, a stylet (or mandrel) is not required to position the sheath. Secondly, the ability to control the trade-off between stiffness and flexibility by pressurizing the guide sheath enables the operator to optimize the compromise between these two parameters depending on the patient's vasculature; moreover, since the pressurization of the sheath can be varied at will, the operator can change the trade-off as the sheath traverses the artery. That is, in tortuous sections, flexibility (steerability) can be favored at the expense of pushability. In straighter, more distal portions of the vasculature, the sheath can be stiffened to enhance pushability. This is particularly beneficial when encountering sharp turns as can occur in the iliac artery of patients suffering aortic aneurysm disease.

Because the sheath is pressurized, the wall of the sheath, particularly in the distal region, can be extremely thin. This increases the potential internal diameter of the sheath relative to the outer diameter and thereby increases the space available to house the graft or graft stent complex; this means that for a given outer diameter, the invention is capable of delivering and deploying a larger stent (or graft stent complex) than is possible in the prior art.

A valuable benefit of the invention is the fact that the sheath can be muzzle loaded with a graft stent complex prior to use. This provides two important advantages over conventional prior art techniques, wherein the graft stent complex is introduced through the proximal end of the sheath after the sheath is in position. In the first place, it avoids the need to traverse the entire length of the guide sheath to position the graft stent complex within the sheath. Secondly, since it is not necessary to introduce the complex through the hemostatic valve at the proximal end of the guide sheath, a smaller hemostatic valve can be used resulting in less blood loss during catheter manipulations.

A further feature of the invention resides in the fact that the use of a lead balloon results in a completely smooth transition between the distal face of the guide sheath and the tapered surface formed by the balloon. This smooth transition avoids the sharp edges which may exist when a stylet system is used, and which may injure the artery and cause dislodgement of intraluminal thrombus and accumulated plaque.

IN THE DRAWINGS

FIGS. 1A and 1B comprise a plan view, partially in section, of a first embodiment of the invention assembled and ready for use prior to lead balloon inflation and sheath pressurization.

FIGS. 2A and 2B are slightly enlarged views of the proximal and distal ends, respectively, of the device shown in FIGS. 1A and 1B with a guide wire in place and the lead balloon at the distal end of the guide sheath inflated;

FIG. 3 is a cross sectional view along the line 3--3 of FIG. 2B;

FIG. 4 is an enlarged side sectional view showing the manner in which the distal end of the deployment catheter is joined to the lead balloon catheter;

FIGS. 5A and 5B are slightly enlarged views showing the device with the deployment balloon positioned within the guide sheath and the lead balloon deflated and extended off and beyond the guide wire;

FIGS. 6A and 6B are slightly enlarged views showing the balloons after the deployment balloon has been inflated to expand the distal stent with the deflated lead balloon previously retracted into the sheath.

FIGS. 7A and 7B comprise a plan view partially in section showing a second embodiment of the invention;

FIG. 8 is a sectional view along the line 8--8 of FIG. 7A;

FIG. 9 is a sectional view along the line 9--9 of FIG. 7B;

FIG. 10 is a plan view partially in section of a handle according to the invention;

FIG. 11 is a top view of the handle;

FIG. 12 is a cross sectional view along the line 12--12 of FIG. 10;

FIG. 13 is an enlarged view of a lead balloon and sheath;

FIG. 14 is a plan view of a third embodiment in which the lead balloon is introduced into the distal end of the sheath; and

FIG. 14A is an enlarged side sectional view of the embodiment of FIG. 14 showing the manner in which the distal end of the deployment catheter is selectively joined to a lead balloon catheter.

DETAILED DESCRIPTION OF THE INVENTION

FIGS. 1-6 illustrate an embodiment of the invention in which separate deployment and lead balloon catheters are used to deploy a graft stent complex shown as comprising a graft 12 and stent 14. Stent 14, for example, may be a conventional Palmaz stent. The specific construction of the device to be deployed is not a feature of the invention.

The delivery and deployment device comprises a guide sheath 20 which is adapted to be positioned within the patient's vasculature to facilitate delivery of the graft stent complex to the location where it is to be deployed. The guide sheath 20 terminates at its proximal end in a three way hemostatic valve 21. Hemostatic valve 21 may be a modified Tuoy Borst hemostatic valve having deployment catheter port 22, an end catheter port 24 and a sheath pressurization port 26 for purposes described below. Hemostatic valve 21 prevents the loss of blood through sheath 20 when its distal end is not sealed. Thumb screws 22A and 24A close ports 22 and 24, also locking in position the catheter which passes through the port.

The sheath pressurization port 26 is connected through a syringe 28 which may be of the type which includes an integral infusion pressure manometer 29 to provide the operator with a continuous indication of the pressure applied by the syringe to the port 26. The syringe 28 may include a piston which is threadedly received within a bracket 31 fixed to the barrel. Pressure is applied by rotating a knob 28A at the end of the piston to advance the piston and apply very precise pressures to the sheath. Syringes of this type are conventional disposable items. The syringe may be integrally formed with the port 28, or the port and syringe may be provided with standard connecting means so that the parts can be selectively coupled together.

The guide sheath 20 contains a deployment catheter 30 and a lead balloon catheter 40. The deployment catheter 30 comprises an elongated flexible shaft 32 which includes a guide wire lumen 34 and an inflation lumen 36 (see FIG. 3). A deployment balloon 38 is mounted on the distal end of the deployment catheter 30 in such a way that it can be inflated and deflated through the inflation lumen 36.

The deployment balloon catheter 30 terminates at its distal end in luer locks 38A and 38B which are connected by means of a standard bifurcated connector 39 to the proximal end of the catheter shaft 32. The luer lock 38A is in fluid communication with the inflation lumen 36 and the luer lock 38B communicates with the guide wire lumen 34. Balloon catheters of this construction are conventional; therefore, the deployment catheter 30 is not described in further detail.

The lead balloon catheter 40 likewise is of conventional construction and includes an elongated flexible shaft 42 which includes a guide wire lumen 44 and an inflation lumen 46. A lead balloon 48 is mounted at the distal end of the catheter 40 and can be selectively inflated and deflated through the inflation lumen 46. A luer lock 49 is attached to the proximal end of the lead balloon catheter 40 so that the balloon 48 can be inflated by the introduction of fluid through the luer lock 49.

The lead balloon shaft 42 includes an opening 50 which, as most clearly shown in FIG. 4, is adapted to receive the distal end of the deployment catheter 30. Opening 50, which may be formed by skiving shaft 42, does not affect the inflation lumen 46 but enables the guide wire lumens 34 and 44 to be aligned in a substantially colinear relationship so that a standard guide wire 52 can be passed from the lead balloon catheter 40 to the guide wire lumen 34 of the deployment catheter 30 during use.

As shown schematically in the drawings, sheath 20 has a constant outer diameter, but the inner diameter of the proximal portion of the sheath (FIG. 1A) is less than the inner diameter of the distal portion (FIG. 1B), i.e. the distal section is more flexible (less stiff) and includes a wider lumen. The proximal portion of the sheath provides increased pushability and torquability of the catheter as it is inserted. Because the graft stent complex is muzzle loaded (as explained below), there is no need for a large internal diameter in the proximal segment of sheath 20 and a thicker wall is feasible.

In the distal portion of the sheath 20, the wall is thin and indeed, may even be flimsy, for example, comparable to cellophane film. Reduction of wall thickness in the distal portion of the sheath provides increased space in which the graft stent complex can be housed, which means that for a given outer diameter, a larger complex is possible with the invention. Pushability of the catheter is enhanced in part by the presence of the stent graft complex within the sheath but, primarily, the stiffness required is achieved by pressurizing the sheath by the introduction of fluid under pressure through port 26 of valve 21. By monitoring the pressure on a manometer 54 during insertion of the sheath, the surgeon can continuously vary the stiffness (and thus pushability and flexibility) of the sheath throughout the insertion procedure. This means that the surgeon has the capability of varying the stiffness of the catheter sheath during different phases of insertion depending on the degree of tortuosity of the vascular system.

The sheath 20 may be made of PTFE (Teflon). The length and characteristics of the sheath will vary depending upon the particular application. Where an aortic aneurysm graft is to be deployed, the sheath 20 may be approximately 60 cm in length with the distalmost 15-20 cm comprising the flexible portion of the sheath. The sheath may be manufactured by standard extrusion techniques with the distal flexible portion thereafter cored from the extruded tube to form a thinner-walled flexible section.

The device may be assembled and sold in the condition shown in FIGS. 1A and 1B, or it may be assembled at the time of use. The method of assembly is as follows.

Deployment catheter 30 and lead balloon catheter 40 are passed through the deployment catheter port 22 and tip catheter port 24 of hemostatic valve 21 with the valve screws 22A and 22B open until the balloons 38 and 48 extend from the distal end of the sheath. If the device is to be used to deploy a graft stent complex 12, 14, the complex is then placed over the distal end of deployment catheter 30 with the balloon 38 beneath the stent 14. In conventional fashion, the stent 14 is crimped to balloon 38. The distal tip of deployment catheter 30 is then inserted into the opening 50 within the shaft 42 of lead balloon catheter 40 so that a continuous or colinear passageway is formed between the guide wire lumens 34 and 44.

The graft stent complex and catheters 30 and 40 are then muzzle loaded into the sheath 20 (i.e., retracted proximally into the sheath) and positioned so that, for example, about haft of the lead balloon 48 extends from the distal end of the sheath 20, as shown in FIG. 2B. The lead balloon 48 may be about four cm. in length which means that approximately two cm. of the balloon will extend distally from the sheath 20. The ability to muzzle load the catheters and graft-stent complex into the sheath is a valuable feature of the invention since it avoids the need to push the graft through the entire sheath which, in view of the length of the sheath, can be time consuming and may result in separation of the graft-stent complex (14,12) from the underlying balloon.

The device is used as follows. A one-way valve 51 (FIG. 2A) is attached to the lead balloon inflation port luer lock 49 and the lead balloon 48 inflated with saline solution from a standard ten cc. syringe 53 attached to luer lock 49. As shown in FIG. 2B, when the balloon 48 is inflated, it seals the distal end of the sheath 20 and provides a smooth taper which facilitates movement of the sheath through the patient's vasculature. Expansion of the balloon also results in a smooth transition between the sheath and balloon (see FIG. 2B) which means that the sheath is less likely to injure the artery or dislodge thrombus or plaque as it is pushed through the artery. The lead balloon also serves to aid in hemostasis, since blood cannot travel back through the sheath and out of the patient while the balloon is inflated.

The syringe 28 attached to the sheath pressurization port 26 is then used to inject saline into sheath 20 to a desired sheath pressure as measured by the infusion pressure manometer. After all air has been evacuated, i.e. the system has been bled, the catheter infusion ports are closed. The device is now ready to be inserted into the patient.

The device is inserted as follows. First, the guide wire 52 is passed through the patient's vasculature with its location being confirmed fluoroscopically. In FIGS. 5A, 5B, 6A and 6B, a blood vessel is shown at 56 for purposes of explanation. The operator then inserts the proximal end of the guide wire into the distal end of the guide wire lumen 44 within lead balloon catheter 40. The operator next introduces sheath 20 into the patient over the guide wire. Because of the way in which the deployment catheter 30 is nested within the lead balloon catheter 40, the guide wire passes from the lead balloon guide wire lumen 44 into the colinear deployment guide wire lumen 34 as shown in FIG. 4. With the inflated lead balloon 48 providing a smooth taper for the pressurized sheath 22, the operator guides the sheath with the enclosed catheters to the location where the stent is to be deployed. As the sheath is being moved, the surgeon can vary its flexibility to accommodate the specific vasculature by adjusting the pressure within the sheath as indicated by manometer 54. The sheath position is determined fluoroscopically in a conventional fashion. For example, the sheath 20 may have regularly placed radiopaque markers so that the exact location of the sheath tip can be identified. When the proper location is reached, lead balloon 48 is deflated using the syringe.

The thumbwheel 24A for the lead balloon catheter 40 is then released and the lead balloon catheter advanced distally (with the position of the deployment catheter 30 held in place) until the catheter 40 is disengaged from the guide wire 52 (FIGS. 5A and 5B). This occurs when the opening 50 moves distally beyond the distal end of the guide wire 52.

The surgeon then retracts the lead balloon catheter 40 back into the sheath 20 to a position proximal of the graft stent complex 12, 14 and tightens the thumb screw 24A to retain the lead balloon catheter in this position.

Next, the thumb screw 22A which secures the deployment catheter 30 is loosened and the sheath 20 retracted to expose the stent 14. The syringe with saline is attached to the luer lock 38B and the deployment balloon 38 is expanded to deploy the stent (FIGS. 6A and 6B). After the stent is fully deployed, the deployment balloon 38 is deflated. It may then be exchanged for a second deployment catheter containing a second stent to be properly positioned with respect to the graft 12 and deployed. Alternatively, graft 12 may be provided with both stents, in which case the deployment catheter 30 can be withdrawn until the deployment balloon 38 is beneath the second stent. The balloon can then be expanded to deploy the second stent. The sheath 20 and catheters 30 and 40 are then removed and a completion angiogram performed.

In the embodiment of FIGS. 7-9 only a single catheter is used. In this embodiment, the catheter comprises an elongated flexible shaft 60 having a central guide wire lumen 62 and peripheral inflation lumens 64 and 66. A lead balloon 68 is provided at the distal end of the catheter 60 for inflation through the lumen 64. A deployment balloon 70 is positioned on the shaft 60 proximally of the lead balloon 68 and adapted to be inflated or deflated by means of the lumen 66. The lead balloon 68 and deployment balloon 70 function the same way as the lead balloon 48 and deployment balloon 38 of the embodiment shown in FIGS. 1-6 but, of course, cannot be separated.

The proximal end of the guide sheath 20 terminates in a hemostatic valve 72 through which the catheter shaft 60 extends. The hemostatic valve 72 includes a port 74 which may be connected to the syringe 28 shown in FIG. 1A. The port 74, of course, provides access to the interior of the sheath 20. A standard hemostatic valve may be used as valve 72.

The catheter shaft 60 terminates in a conventional trifurcated fitting 76 having three proximal ports which terminate in luer lock 78, 80, and 82. The luer locks 78 and 82 provide access to the inflation lumens 64 and 66, respectively, while the luer lock 80 provides access to the guide wire lumen 62. In this case the guide wire 52 is inserted in conventional fashion through the guide wire lumen 62 of the catheter shaft 60. A one-way valve would be connected to luer lock 78 to maintain the inflation of the lead balloon during use.

The components illustrated may be conventional. For example, hemostatic valve 21 may be an ANGEDAPT Y-connector manufactured by Angeion Medical Products, Model No. AYC-020. Hemostatic valve 72 may be of the type sold by Universal Medical Instrument Corp. under the trademark CATH-SEAL (Model No. 1200-90-3003). The pressure syringe 28 may be a LeVeen disposable inflation syringe with pressure gauge manufactured by the MedTech Division of Boston Scientific (Model No. 15-101).

In the illustrated embodiments, the guide sheath comprises a relatively stiff flexible portion and a relatively flexible distal portion. It is conceivable that it may prove beneficial to have a continuously variable change in stiffness/flexibility, in which case the inner wall may taper gradually with the diameter increasing from the proximal end to the distal end. It is also possible that stiffness/flexibility may vary in a number of discrete steps, rather than in a single step as illustrated.

It is also contemplated that the entire sheath can be made of a highly flexible plastic (e.g., PTFE), which can be folded so as to reduce its cross section prior to insertion. The advantage of this construction is that a small introducer (and thus a smaller hole in the patient's artery) could be used to introduce the sheath into the patient's artery. Once in position, the sheath would be pressurized as described in the foregoing to increase its diameter as required for delivery and deployment of the stent.

In addition to varying the pressure of the sheath as it passes through the patient's vasculature, it is also possible to vary the pressure applied to the lead balloon so that the operator can vary the flexibility of the leading surface of the sheath as it traverses the vasculature, should this be desirable.

In the process of retracting the sheath so that the stent can be deployed, the possibility exists that the stent may be moved accidentally with respect to the patient's artery. FIGS. 10-12 illustrate a handle mechanism which, in use, reduces the likelihood of stent displacement when the physician retracts the sheath.

FIGS. 10-12 illustrate a handle construction for use with the two balloon embodiment shown in FIGS. 7-9 although the handle would have equal utility with the two catheter embodiment of FIGS. 1-6. In FIGS. 10-12 the same numerals are used to identify corresponding parts although some parts are illustrated as slightly different in appearance.

As shown in FIGS. 10-12, the proximal end of the sheath 20 is slidably retained within a handle 100 which includes an elongated slot 102 through which port 74 of the hemostatic valve 72 extends. The catheter shaft 60 extends through a locking screw 104 attached to the proximal end of the handle 100 and through a locking screw 106 of the hemostatic valve 72 into the sheath 20. The hemostatic valve includes a distal stop 108 adapted to abut against the distal edge 109 of slot 102 and a proximal stop 110 adapted to abut against the proximal edge 111 of slot 102.

In use, hemostatic valve 72 is pushed distally until the stop 108 abuts edge 109 of slot 102. The locking screw 106 is loosened to permit movement of the valve 72 relative to the catheter shaft 60. Locking screw 104, however, is tightened so that the handle 100 cannot move relative to the catheter shaft 60.

After the stent has been positioned as explained above, and it is time to retract the sheath so that the stent can be deployed, the physician holds the handle in one hand and pulls back on the port 74 until stop 110 abuts against the edge 111 of slot 102. Because the locking screw 104 retains the catheter 60 with respect to the handle 100, the sheath 20 is moved relative to the catheter 60 the distance determined by the length of slot 102 and the positions of the stops 108 and 110. This permits the physician to hold the catheter 60 (and thus the stent) in a fixed location and withdraw the sheath by a precise amount. Therefore, the likelihood of human error causing improper positioning of the stent when the sheath is retracted is reduced.

When the sheath is pressurized, a substantial pressure is applied to the lead balloon which, obviously, must not be expelled when the sheath is pressurized. Accordingly, as shown in FIG. 13, to aid in retaining the lead balloon 48 within sheath 20, the inner surface of the distal end of sheath 20 and the outer surface of the lead balloon 48 may be provided with mating circumferential ribs and grooves. These grooves may extend over about 1/2 inch and will prevent accidental expulsion of the lead balloon when sheath 20 is pressurized. Other comparable means may be used to retain the expanded lead balloon within the pressurized sheath 20.

FIGS. 14 shows an embodiment of the invention in which the lead balloon is mounted on a separate lead balloon catheter adapted to be introduced into the distal end of the sheath. The construction of FIG. 14 is designed for use in a novel stent deployment procedure, described below, which is of special utility with patients having a tortuous vasculature through which it is difficult to move a stent deployment catheter. Before describing the procedure, the catheter construction is described. In FIG. 14, parts corresponding to the parts shown in the embodiment of FIGS. 7-9 bear the same numbers. In this embodiment, the catheter 60 serves as a stent deployment catheter. It supports an inflatable balloon 70 on which stent 14 is mounted for deployment as explained above. Balloon 70 and stent 14 are retained within the sheath 20 which may be pressurized as described above.

The lead balloon 68 is on a separate lead balloon catheter 120. The adjoining ends of the lead balloon catheter 120 and the deployment catheter 60 can be connected together in any suitable fashion which enables the catheters to be selectively connected and disconnected. For example, the end of lead balloon catheter 120 may be tapered and include a circumferential 122 detent adapted to engage a mating rim 124 on the deployment catheter 60 so that the two catheters are held securely together, as shown in detail in FIG. 14A. Numerous other connecting means such as bayonet type connecters, threaded connectors, etc. can be used. The object is to make sure that the two catheters are securely held together during use but, as explained below, in such a way that they can be separated when it is necessary to withdraw them from the patient's vasculature.

In cross section, the catheter 60 and 120 may be similar to the cross section shown in FIG. 8 with a central lumen through which a guidewire 52 passes. In each case, only a single inflation lumen 64 (or 66) is necessary.

A small port 126 may be provided in the catheter 120 for the purpose of introducing an angiographic contrast material as described in further detail below. When a contrast material is to be introduced through the catheter, a conventional one-way valve (not shown) should be provided in front of the port 126 (to the right of the port as illustrated in FIG. 14) so that the contrast material introduced into the central lumen will be blocked from flowing through the guide wire lumen and thus will exit through the port 126.

The catheter construction of FIG. 14 is designed to enable two physicians to simultaneously push and pull the deployed stent through the patient's vasculature. This is particularly beneficial in the case of patients with tortuous arteries as frequently encountered in the case of elderly patients. The way in which this is achieved is explained in the following.

Using a needle puncture technique a needle is inserted into the brachial artery in the patient's arm through a percutaneous approach. This needle is guided by palpating the pulse of the brachial artery and thereby advanced into the lumen of the artery. Through this needle, guidewire 52 is inserted and advanced into the lumen of the artery. Under fluoroscopic control, the guidewire is advanced retrograde (against the flow of blood) within the brachial artery to the axillary artery. From the axillary artery the wire moves directly into the left subclavian artery which connects directly with the thoracic portion of the aorta. When the wire has entered the aorta in this retrograde fashion, it is advanced under fluoroscopic control down the thoracic aorta into the abdominal aorta. Once it has reached the distal end of the abdominal aorta it is selectively directed into either the right or left common iliac artery. The side into which the wire is directed depends upon which artery has been chosen for subsequently advancing the sheath 20 and the stent deployment catheter 60. Generally, the larger of the two iliac arteries is chosen as the access vessel.

The wire 52 is then advanced under fluoroscopic control down through the common iliac artery into the external iliac artery and finally into the common femoral artery. Once the wire has reached the common femoral artery an incision is made into the common femoral artery. The wire is visualized and drawn out of this incision and left coiled outside the body. At this point one end of a very long wire is coiled outside of the femoral artery in the groin and the other end of this very long wire is coiled outside the body through a percutaneous puncture of the brachial artery in the left arm.

Using an over-the-wire technique, the lead balloon catheter 120 is advanced through the percutaneous puncture in the left brachial artery over the wire through all the vessels previously described down through the aorta and out the appropriate iliac artery, continuously following the guidewire 52. Once the balloon has emerged out of the common femoral artery, the stent deployment device is ready for use. The tip of lead balloon catheter 120 is inserted into the distal end of deployment catheter so that the detent 122 and ridge 124 are locked together to form a tight union. After this union has been established, the lead balloon catheter 120 is advanced into the distal end of the sheath 20 so that approximately half of the balloon 168 is inside the sheath while the remaining half of the balloon is outside the sheath. The lead balloon 68 is then inflated to maximum pressure thereby providing a smooth taper at the distal end of sheath 20.

With the lead balloon 68 fully inflated and locked into position, the distal end of the sheath 20 and lead balloon are carefully inserted into the previously created arteriotomy in the femoral artery. This process is done by slowly pulling back slack on the lead balloon catheter 120 in the arm as the sheath 20 is advanced into the femoral artery and then retrograde into the external iliac artery.

The sheath 20, at this juncture, is then pressurized to an appropriate pressure as previously described to produce an optimized balance of flexibility and pushability. Once pressurization of the sheath 20 has been accomplished, by gently pulling on the lead balloon catheter 120 at it origin in the brachial artery while simultaneously pushing the sheath 20 from its distal end into the iliac artery, the entire system is advanced from the iliac arteries into the abdominal aorta and into a suitable position for deployment of the stent graft. When the sheath 20 has reached the appropriate position in the abdominal aorta, the lead balloon 60 is deflated. The sheath 20 covering the stent 14 is then withdrawn to expose the stent and graft. To ensure exact positioning of the stent in an appropriate position in relationship to surrounding branch arteries, an arteriogram may be performed. This arteriogram is performed as follows.

The guide wire 52 which extends from the brachial artery to the common femoral artery is first removed. The one way valve in the tip of the lead balloon catheter 120 permits only retrograde fluid flow in the catheter. Removing the guide wire 52 closes the valve mechanism permitting pressurization of the central lumen of the lead balloon catheter 120. Angiographic contrast material is injected through the external port of lead balloon catheter 120 into the guide wire lumen of the catheter and exits from port 126 in the catheter shaft. Contrast cannot continue down the balloon catheter shaft because the closed valve occludes the passage way. This angiogram injection will permit final localization of the appropriate position for the stent graft.

Once the angiogram has been completed, the guide wire 52 is then reinserted through the groin and out through the brachial artery. At this point, sheath 20 is retracted and the deployment balloon 70 inflated to deploy the stent 14. During inflation of the deployment balloon 70, tension is maintained on the lead balloon catheter shaft 120 (with lead balloon 68 deflated). By so doing, distal migration of the stent and deployment balloon secondary to the downward motion of the pumping circulation, can be avoided. Traction on the lead balloon catheter 120 which is attached to the deployment balloon 60 will aid in the stabilization of this balloon during deployment and prevent distal migration. Once the proximal stent of the stent graft has been deployed, the catheters 120 and 60 are disconnected either by applying gentle opposite tension to both balloon catheter shafts or by advancing the tips of both catheters out of the common femoral artery where they can be disengaged manually. Additional procedures including the placement of additional stents could then be performed using well described standard techniques.

The foregoing description relates to the deployment of an aortic stent graft or stent but the principals of the invention may be used for the passage of other transluminal devices into other vascular systems using this push-pull technique.

Many modifications of the illustrated embodiments are possible within the scope of the invention. For example, the stent deployment means may comprise a mechanical device rather than a balloon. One suitable device for mechanically deploying a stent is shown in U.S. patent application Ser. No. 08/196,278, U.S. Pat. No. 5,443,477 filed Feb. 10, 1994, in the names of Michael and Ralph Marin, and entitled APPARATUS AND METHOD FOR DEPLOYMENT OF RADIALLY EXPANDABLE STENTS BY A MECHANICAL LINKAGE.

Furthermore, although the invention has been described for use in the delivery and deployment of stents and graft stent complexes, the broad principles of the invention can be used in the delivery and/or deployment of other intraluminal devices such as but not limited to VenaCava filters, atherectomy devices and the like.

Instead of using a guide wire, a balloon catheter may be introduced into the thoracic aorta and the balloon expanded to permit the blood flow to push the catheter distally to a desired location such as the common femoral artery. The right or left artery can be selected by applying pressure to one artery causing the balloon to move to the other. The catheter can then be pulled from the artery and used as explained above or in any desired way to simultaneously push and pull an intraluminal device through the patient's arteries.

Claims (18)

What is claimed is:
1. A device for delivering and deploying an intraluminal device, comprising:
a guide sheath having proximal and distal ends;
a lead balloon within said sheath, at least a portion of said lead balloon extending from the distal end of said guide sheath to provide a tapered leading surface and a fluid-tight seal at the distal end of said guide sheath; and
a catheter within said sheath, said catheter containing an intraluminal device and having means for deploying said intraluminal device.
2. A device for delivering and deploying an intraluminal device according to claim 1, further including
a handle, the proximal end of said guide sheath being retained within said handle, said catheter extending through said guide sheath and out of the handle, and
means for selectively locking the catheter and handle together so that said guide sheath can be moved selectively relative to said handle and catheter.
3. A device for delivering and deploying an intraluminal device according to claim 2, wherein there is provided an element accessible from the exterior of the handle for moving said guide sheath relative to the handle, and wherein said element is moveable a predetermined distance to enable said intraluminal device to be deployed.
4. A device for delivering and deploying an intraluminal device according to claim 1, including
a lead balloon catheter, said lead balloon catheter containing said lead balloon near one and thereof, end
means for selectively connecting said one end of said lead balloon catheter to a distal end of the catheter containing the intraluminal device.
5. A device for delivering and deploying an intraluminal device according to claim 4, wherein said lead balloon catheter includes a guide wire lumen, a port for injecting a contrast dye into the patient's vasculature through said guide wire lumen, and a valve within said guide wire lumen for causing dye injected into said lumen to be expelled through said port.
6. A device for delivering and deploying an intraluminal device according to claim 4, further including
pressurizing means for applying a fluid under pressure to said guide sheath to control the flexibility of the guide sheath when said lead balloon is inflated to seal the distal end of the guide sheath.
7. A device for delivering and deploying an intraluminal device according to claim 1, wherein said intraluminal device comprises a stent, said stent being mounted on said deployment means.
8. A device for delivering and deploying an intraluminal device according to claim 6, wherein at least a portion of the lead balloon and the sheath which contact each other when the lead balloon is inflated include cooperating means for retaining the inflated lead balloon within the sheath.
9. A device for delivering and deploying an intraluminal device comprising:
a guide sheath having proximal and distal ends, said guide sheath being formed from a material that allows the flexibility of said guide sheath to be varied by varying internal pressure within said guide sheath; and
a tip element slidably positionable adjacent said distal end of said guide sheath to form a leading end for said guide sheath; wherein:
said tip element forms a fluid-tight seal with said distal end of said guide sheath when positioned adjacent said distal end of said guide sheath so that internal pressure is increased within said guide sheath in response to applied pressure within said guide sheath; and
said tip element is slidable away from said distal end of said guide sheath to allow delivery and deployment of an intraluminal device carried within said guide sheath through said guide sheath.
10. A device for delivering and deploying an intraluminal device as in claim 9, further comprising at least one rib on one of said guide sheath and said tip element and at least one groove on the other of said guide sheath and said tip element for mating with said rib when said tip element is adjacent said distal end of said guide sheath to form a fluid-tight seal.
11. A device for delivering and deploying an intraluminal device as in claim 9, wherein said tip element is smooth, closed, and tapered.
12. A device for delivering and deploying an intraluminal device as in claim 11, wherein said tip element is an inflatable balloon.
13. A device for delivering and deploying an intraluminal device comprising:
a guide sheath having proximal and distal ends;
a catheter within said sheath, said catheter containing an intraluminal device and having means for deploying said intraluminal device; and
a handle, the proximal end of said guide sheath being retained within said handle, said catheter extending through said guide sheath and out of said handle; and
means for selectively locking said catheter and handle together so that said guide sheath can be moved selectively relative to said handle and catheter to expose said intraluminal device on said catheter.
14. A device for delivering and deploying an intraluminal device as in claim 13, further including an element accessible from the exterior of said handle for moving said guide sheath relative to the handle, wherein said element is moveable a predetermined distance to enable said intraluminal device to be fully exposed and deployed.
15. A device for delivering and deploying an intraluminal device as in claim 14, wherein a slot is defined in said handle, said element accessible from the exterior of said handle being joined to said guide sheath and passing through said slot.
16. A method of delivering and deploying an intraluminal device in a blood vessel, comprising the steps of:
providing a guide sheath having at least a distal portion, at least said distal portion of said guide sheath being made of a soft flexible material that allows the internal pressure of said guide sheath to be varied to alter the flexibility of said guide sheath;
placing an intraluminal device within said guide sheath;
maintaining said distal portion of said guide sheath in a configuration that reduces the cross section of said guide sheath prior to insertion into a blood vessel;
providing a tip element adjacent said distal portion of said guide sheath;
inserting the reduced cross section guide sheath into a blood vessel;
increasing internal pressure within said guide sheath to increase the cross section of said guide sheath and to increase pushability of said guide sheath through said blood vessel;
forming a fluid right seal between said tip element and said distal portion of said guide sheath at least while increasing internal pressure in said guide sheath;
moving said tip element away from said distal portion of said guide sheath once said guide sheath is in position to deploy said intraluminal device;
sliding said intraluminal device from within said guide sheath out into said blood vessel; and
deploying said intraluminal device within said blood vessel.
17. A method of delivering and deploying an intraluminal device into a blood vessel as in claim 16, further comprising the step of varying the internal pressure of said guide sheath as said guide sheath is pushed through the blood vessel to adjust the flexibility of said guide sheath.
18. A method of delivering and deploying an intraluminal device into a blood vessel as in claim 16, wherein said tip element comprises an inflatable balloon, said method further comprising the step of inflating said balloon to provide said fluid tight seal before increasing internal pressure within said guide sheath.
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Cited By (108)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5788708A (en) * 1996-09-20 1998-08-04 Intella Interventional Systems, Inc. Multiple balloon stent delivery catheter and method
US5944727A (en) * 1998-09-02 1999-08-31 Datascope Investment Corp. Stent/graft catheter handle
US6152945A (en) * 1997-04-23 2000-11-28 St. Jude Medical Cardiovascular Group, Inc. Tubular medical graft connectors
US6156063A (en) * 1997-02-20 2000-12-05 Endologix, Inc. Method of deploying bifurcated vascular graft
US6174327B1 (en) 1998-02-27 2001-01-16 Scimed Life Systems, Inc. Stent deployment apparatus and method
US6190360B1 (en) 1999-04-09 2001-02-20 Endotex Interventional System Stent delivery handle
US6231496B1 (en) * 1999-07-07 2001-05-15 Peter J. Wilk Medical treatment method
US6331190B1 (en) 1998-03-04 2001-12-18 Endologix, Inc. Endoluminal vascular prosthesis
US6383204B1 (en) 1998-12-15 2002-05-07 Micrus Corporation Variable stiffness coil for vasoocclusive devices
US6432127B1 (en) 1996-10-11 2002-08-13 Transvascular, Inc. Devices for forming and/or maintaining connections between adjacent anatomical conduits
US6478813B1 (en) 1997-08-01 2002-11-12 Peter T. Keith Method for joining grafts in a common body passageway
US6482227B1 (en) 1998-03-30 2002-11-19 Cordis Corporation Stent graft having improved attachment within a body vessel
US20020173785A1 (en) * 2000-03-31 2002-11-21 Medtronic, Inc. System and method for positioning implantable medical devices within coronary veins
US20020193863A1 (en) * 2000-09-18 2002-12-19 Endotex Interventional Systems, Inc. Apparatus for delivering endoluminal prosthesis and methods for preparing such apparatus for delivery
US6500202B1 (en) 1998-12-11 2002-12-31 Endologix, Inc. Bifurcation graft deployment catheter
US6508835B1 (en) 1998-12-11 2003-01-21 Endologix, Inc. Endoluminal vascular prosthesis
US6514261B1 (en) 1998-09-30 2003-02-04 Impra, Inc. Delivery mechanism for implantable stent
US6527779B1 (en) 2000-07-10 2003-03-04 Endotex Interventional Systems, Inc. Stent delivery device
US6533782B2 (en) 2000-05-18 2003-03-18 Wilson-Cook Medical Incorporated Medical device with improved wire guide access
US6575994B1 (en) 1994-02-10 2003-06-10 Teramed, Inc. Method and apparatus concerning bypass grafts
US20030135258A1 (en) * 2001-12-03 2003-07-17 Xtent, Inc. Apparatus and methods for delivery of braided prostheses
US6602226B1 (en) 2000-10-12 2003-08-05 Scimed Life Systems, Inc. Low-profile stent delivery system and apparatus
US6626938B1 (en) 2000-11-16 2003-09-30 Cordis Corporation Stent graft having a pleated graft member
US6660030B2 (en) 1998-12-11 2003-12-09 Endologix, Inc. Bifurcation graft deployment catheter
US20040034383A1 (en) * 2001-07-31 2004-02-19 Amir Belson Flow-directed catheter guide with variable rigidity shaft
US6733500B2 (en) 2000-03-31 2004-05-11 Medtronic, Inc. Method and system for delivering a medical electrical lead within a venous system
US6733523B2 (en) 1998-12-11 2004-05-11 Endologix, Inc. Implantable vascular graft
US20040093061A1 (en) * 2001-12-03 2004-05-13 Xtent, Inc. A Delaware Corporation Apparatus and methods for delivery of multiple distributed stents
US6743219B1 (en) 2000-08-02 2004-06-01 Cordis Corporation Delivery apparatus for a self-expanding stent
US20040111145A1 (en) * 2002-11-27 2004-06-10 Francesco Serino Vascular prosthesis for the treatment of abdominal aortic aneurysms, using a combined laparoscopic/ open and endovascular technique, and delivery system for releasing a prosthesis fitted with anchoring stents
US20040215331A1 (en) * 2001-12-03 2004-10-28 Xtent, Inc. Apparatus and methods for delivery of variable length stents
US20040249435A1 (en) * 2003-06-09 2004-12-09 Xtent, Inc. Stent deployment systems and methods
US20050010276A1 (en) * 2001-12-03 2005-01-13 Xtent, Inc. Apparatus and methods for positioning prostheses for deployment from a catheter
US20050085888A1 (en) * 2003-10-15 2005-04-21 Xtent, Inc. Implantable stent delivery devices and methods
US20050125479A1 (en) * 2003-12-08 2005-06-09 Luciano Zoso Hardware for performing an arithmetic function
US20050149159A1 (en) * 2003-12-23 2005-07-07 Xtent, Inc., A Delaware Corporation Devices and methods for controlling and indicating the length of an interventional element
US6945989B1 (en) 2000-09-18 2005-09-20 Endotex Interventional Systems, Inc. Apparatus for delivering endoluminal prostheses and methods of making and using them
US20050256092A1 (en) * 2002-08-01 2005-11-17 Shin Shimaoka Antipsoriatic agent
US20060135340A1 (en) * 2002-07-30 2006-06-22 Cheang Hong N P Spherical nano-composite powder and a method of preparing the same
US20060206188A1 (en) * 2005-03-14 2006-09-14 Jan Weber Bifurcation delivery system
US20060253185A1 (en) * 2005-05-09 2006-11-09 Medtronic Vascular, Inc. Catheter for stent delivery having expanded inner member
US20060253184A1 (en) * 2005-05-04 2006-11-09 Kurt Amplatz System for the controlled delivery of stents and grafts
US20060259123A1 (en) * 2003-09-25 2006-11-16 C. R. Bard, Inc. Lining for bodily lumen
US20060271151A1 (en) * 2005-05-31 2006-11-30 Xtent, Inc. In situ stent formation
US20070005122A1 (en) * 2004-09-24 2007-01-04 Olympus Corporation Treatment instrument installation member, stent delivery catheter and conduit system
US7169170B2 (en) 2002-02-22 2007-01-30 Cordis Corporation Self-expanding stent delivery system
US20070083256A1 (en) * 2003-04-28 2007-04-12 C.R. Bard, Inc. Loading and delivery of self-expanding stents
US20070118207A1 (en) * 2005-05-04 2007-05-24 Aga Medical Corporation System for controlled delivery of stents and grafts
US7270668B2 (en) 2001-12-03 2007-09-18 Xtent, Inc. Apparatus and methods for delivering coiled prostheses
US7300456B2 (en) 2004-06-28 2007-11-27 Xtent, Inc. Custom-length self-expanding stent delivery systems with stent bumpers
US7309350B2 (en) 2001-12-03 2007-12-18 Xtent, Inc. Apparatus and methods for deployment of vascular prostheses
US7351255B2 (en) 2001-12-03 2008-04-01 Xtent, Inc. Stent delivery apparatus and method
US7402168B2 (en) 2005-04-11 2008-07-22 Xtent, Inc. Custom-length stent delivery system with independently operable expansion elements
US7553324B2 (en) 2003-10-14 2009-06-30 Xtent, Inc. Fixed stent delivery devices and methods
US20100070016A1 (en) * 2008-09-16 2010-03-18 C. R. Bard, Inc. Stent device adhesively bonded to a stent device pusher
US7744619B2 (en) 2004-02-24 2010-06-29 Boston Scientific Scimed, Inc. Rotatable catheter assembly
US20100204771A1 (en) * 2009-02-11 2010-08-12 Boston Scientific Scimed, Inc. Medical device having a rotatable shaft
US7892273B2 (en) 2001-12-03 2011-02-22 Xtent, Inc. Custom length stent apparatus
US7905913B2 (en) 2001-12-03 2011-03-15 Xtent, Inc. Apparatus and methods for delivery of multiple distributed stents
US7922740B2 (en) 2004-02-24 2011-04-12 Boston Scientific Scimed, Inc. Rotatable catheter assembly
US7938851B2 (en) 2005-06-08 2011-05-10 Xtent, Inc. Devices and methods for operating and controlling interventional apparatus
US8034100B2 (en) 1999-03-11 2011-10-11 Endologix, Inc. Graft deployment system
US8080048B2 (en) 2001-12-03 2011-12-20 Xtent, Inc. Stent delivery for bifurcated vessels
US20110319902A1 (en) * 2010-06-26 2011-12-29 Scott Epstein Catheter delivery system
US8118856B2 (en) 2009-07-27 2012-02-21 Endologix, Inc. Stent graft
US8133199B2 (en) 2008-08-27 2012-03-13 Boston Scientific Scimed, Inc. Electroactive polymer activation system for a medical device
US8142487B2 (en) 2001-03-29 2012-03-27 Xtent, Inc. Balloon catheter for multiple adjustable stent deployment
US8157851B2 (en) 2005-06-08 2012-04-17 Xtent, Inc. Apparatus and methods for deployment of multiple custom-length prostheses
US8167925B2 (en) 1999-03-11 2012-05-01 Endologix, Inc. Single puncture bifurcation graft deployment system
US8216295B2 (en) 2008-07-01 2012-07-10 Endologix, Inc. Catheter system and methods of using same
US8236040B2 (en) 2008-04-11 2012-08-07 Endologix, Inc. Bifurcated graft deployment systems and methods
US8252036B2 (en) 2006-07-31 2012-08-28 Syntheon Cardiology, Llc Sealable endovascular implants and methods for their use
US8257427B2 (en) 2001-09-11 2012-09-04 J.W. Medical Systems, Ltd. Expandable stent
US20120226341A1 (en) * 2011-03-01 2012-09-06 Endologix, Inc. Catheter system and methods of using same
US8282680B2 (en) 2003-01-17 2012-10-09 J. W. Medical Systems Ltd. Multiple independent nested stent structures and methods for their preparation and deployment
US8317859B2 (en) 2004-06-28 2012-11-27 J.W. Medical Systems Ltd. Devices and methods for controlling expandable prostheses during deployment
US8460358B2 (en) 2004-03-30 2013-06-11 J.W. Medical Systems, Ltd. Rapid exchange interventional devices and methods
US8486132B2 (en) 2007-03-22 2013-07-16 J.W. Medical Systems Ltd. Devices and methods for controlling expandable prostheses during deployment
US8491646B2 (en) 2009-07-15 2013-07-23 Endologix, Inc. Stent graft
US8523931B2 (en) 2007-01-12 2013-09-03 Endologix, Inc. Dual concentric guidewire and methods of bifurcated graft deployment
US8652198B2 (en) 2006-03-20 2014-02-18 J.W. Medical Systems Ltd. Apparatus and methods for deployment of linked prosthetic segments
US8652193B2 (en) 2005-05-09 2014-02-18 Angiomed Gmbh & Co. Medizintechnik Kg Implant delivery device
US8679172B2 (en) 2009-01-29 2014-03-25 C. R. Bard, Inc. Delivery device for delivering a stent device
US8769796B2 (en) 2008-09-25 2014-07-08 Advanced Bifurcation Systems, Inc. Selective stent crimping
US8795347B2 (en) 2008-09-25 2014-08-05 Advanced Bifurcation Systems, Inc. Methods and systems for treating a bifurcation with provisional side branch stenting
US8808347B2 (en) 2008-09-25 2014-08-19 Advanced Bifurcation Systems, Inc. Stent alignment during treatment of a bifurcation
US8821562B2 (en) 2008-09-25 2014-09-02 Advanced Bifurcation Systems, Inc. Partially crimped stent
US8870908B2 (en) 2007-08-17 2014-10-28 DePuy Synthes Products, LLC Twisted primary coil for vascular therapy
US8920484B2 (en) 2009-05-29 2014-12-30 C. R. Bard, Inc. Transluminal delivery system
US8945202B2 (en) 2009-04-28 2015-02-03 Endologix, Inc. Fenestrated prosthesis
US8979917B2 (en) 2008-09-25 2015-03-17 Advanced Bifurcation Systems, Inc. System and methods for treating a bifurcation
US8980297B2 (en) 2007-02-20 2015-03-17 J.W. Medical Systems Ltd. Thermo-mechanically controlled implants and methods of use
US9101503B2 (en) 2008-03-06 2015-08-11 J.W. Medical Systems Ltd. Apparatus having variable strut length and methods of use
US9254210B2 (en) 2011-02-08 2016-02-09 Advanced Bifurcation Systems, Inc. Multi-stent and multi-balloon apparatus for treating bifurcations and methods of use
US9327068B2 (en) 1999-09-03 2016-05-03 Maquet Cardiovascular Llc Guidable intravascular blood pump and related methods
US9364356B2 (en) 2011-02-08 2016-06-14 Advanced Bifurcation System, Inc. System and methods for treating a bifurcation with a fully crimped stent
US9393100B2 (en) 2010-11-17 2016-07-19 Endologix, Inc. Devices and methods to treat vascular dissections
WO2016115252A1 (en) * 2015-01-13 2016-07-21 Pigott John P Balloon catheter having a retractable sheath and locking mechanism
US9408607B2 (en) 2009-07-02 2016-08-09 Edwards Lifesciences Cardiaq Llc Surgical implant devices and methods for their manufacture and use
US9566178B2 (en) 2010-06-24 2017-02-14 Edwards Lifesciences Cardiaq Llc Actively controllable stent, stent graft, heart valve and method of controlling same
US9579103B2 (en) 2009-05-01 2017-02-28 Endologix, Inc. Percutaneous method and device to treat dissections
US9585743B2 (en) 2006-07-31 2017-03-07 Edwards Lifesciences Cardiaq Llc Surgical implant devices and methods for their manufacture and use
US9737424B2 (en) 2008-09-25 2017-08-22 Advanced Bifurcation Systems, Inc. Partially crimped stent
US9814611B2 (en) 2007-07-31 2017-11-14 Edwards Lifesciences Cardiaq Llc Actively controllable stent, stent graft, heart valve and method of controlling same
US9827093B2 (en) 2011-10-21 2017-11-28 Edwards Lifesciences Cardiaq Llc Actively controllable stent, stent graft, heart valve and method of controlling same
US9872788B2 (en) 2011-05-05 2018-01-23 Relief Therapies, Inc. Device for protecting hemorrhoids
US10130798B2 (en) 2013-07-15 2018-11-20 John P. Pigott Balloon catheter having a retractable sheath and locking mechanism
US10245166B2 (en) 2017-05-31 2019-04-02 Endologix, Inc. Apparatus and method of placement of a graft or graft system

Families Citing this family (169)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2060067A1 (en) * 1991-01-28 1992-07-29 Lilip Lau Stent delivery system
US6029671A (en) * 1991-07-16 2000-02-29 Heartport, Inc. System and methods for performing endovascular procedures
CA2079417C (en) 1991-10-28 2003-01-07 Lilip Lau Expandable stents and method of making same
US6770066B1 (en) 1992-05-11 2004-08-03 Ballard Medical Products Multi-lumen endoscopic catheter
US5498227A (en) 1993-09-15 1996-03-12 Mawad; Michel E. Retrievable, shielded radiotherapy implant
WO1996039997A2 (en) * 1995-06-07 1996-12-19 Stentco, Inc. Device and method for delivering and deploying intraluminal devices
US5507769A (en) 1994-10-18 1996-04-16 Stentco, Inc. Method and apparatus for forming an endoluminal bifurcated graft
US5662675A (en) * 1995-02-24 1997-09-02 Intervascular, Inc. Delivery catheter assembly
US6235021B1 (en) * 1995-05-01 2001-05-22 Scimed Life Systems, Inc. Ablation sheath
US5662614A (en) * 1995-05-09 1997-09-02 Edoga; John K. Balloon expandable universal access sheath
US5639274A (en) * 1995-06-02 1997-06-17 Fischell; Robert E. Integrated catheter system for balloon angioplasty and stent delivery
EP0851746A1 (en) * 1995-09-18 1998-07-08 W.L. GORE & ASSOCIATES, INC. A delivery system for intraluminal vascular grafts
EP0954248B1 (en) 1995-10-13 2004-09-15 Transvascular, Inc. Apparatus for bypassing arterial obstructions and/or performing other transvascular procedures
US6375615B1 (en) * 1995-10-13 2002-04-23 Transvascular, Inc. Tissue penetrating catheters having integral imaging transducers and their methods of use
US6709444B1 (en) * 1996-02-02 2004-03-23 Transvascular, Inc. Methods for bypassing total or near-total obstructions in arteries or other anatomical conduits
US6302875B1 (en) * 1996-10-11 2001-10-16 Transvascular, Inc. Catheters and related devices for forming passageways between blood vessels or other anatomical structures
AT440559T (en) * 1995-10-13 2009-09-15 Medtronic Vascular Inc Device for the transvascular interstitial intervened
US5749848A (en) * 1995-11-13 1998-05-12 Cardiovascular Imaging Systems, Inc. Catheter system having imaging, balloon angioplasty, and stent deployment capabilities, and method of use for guided stent deployment
US5746764A (en) * 1995-12-04 1998-05-05 Atrion Medical Products, Inc. Stent compression instrument
US5690642A (en) 1996-01-18 1997-11-25 Cook Incorporated Rapid exchange stent delivery balloon catheter
AUPN775296A0 (en) 1996-01-25 1996-02-22 Endogad Research Pty Limited Directional catheter
DE19607575C2 (en) * 1996-02-29 1999-11-18 Ruesch Willy Ag An apparatus for intraoperative calibration of a collar during a fundoplication
US5643279A (en) * 1996-03-12 1997-07-01 Cordis Corporation Method of catheter balloon manufacture and use
US6533805B1 (en) 1996-04-01 2003-03-18 General Surgical Innovations, Inc. Prosthesis and method for deployment within a body lumen
US5947978A (en) 1996-04-15 1999-09-07 Medical Innovations Corp. Surgical combination apparatus having first and second instruments operated from a common actuator
US5709701A (en) * 1996-05-30 1998-01-20 Parodi; Juan C. Apparatus for implanting a prothesis within a body passageway
US6077295A (en) 1996-07-15 2000-06-20 Advanced Cardiovascular Systems, Inc. Self-expanding stent delivery system
US5968068A (en) * 1996-09-12 1999-10-19 Baxter International Inc. Endovascular delivery system
US8211167B2 (en) 1999-12-06 2012-07-03 Boston Scientific Scimed, Inc. Method of using a catheter with attached flexible side sheath
US6692483B2 (en) 1996-11-04 2004-02-17 Advanced Stent Technologies, Inc. Catheter with attached flexible side sheath
AT539702T (en) * 1996-11-04 2012-01-15 Advanced Stent Tech Inc Apparatus for ausdehnnen a stent and method for its deployment
US6599316B2 (en) 1996-11-04 2003-07-29 Advanced Stent Technologies, Inc. Extendible stent apparatus
US7341598B2 (en) 1999-01-13 2008-03-11 Boston Scientific Scimed, Inc. Stent with protruding branch portion for bifurcated vessels
US6884258B2 (en) 1999-06-04 2005-04-26 Advanced Stent Technologies, Inc. Bifurcation lesion stent delivery using multiple guidewires
US7220275B2 (en) 1996-11-04 2007-05-22 Advanced Stent Technologies, Inc. Stent with protruding branch portion for bifurcated vessels
US6325826B1 (en) 1998-01-14 2001-12-04 Advanced Stent Technologies, Inc. Extendible stent apparatus
US7591846B2 (en) 1996-11-04 2009-09-22 Boston Scientific Scimed, Inc. Methods for deploying stents in bifurcations
US8298280B2 (en) 2003-08-21 2012-10-30 Boston Scientific Scimed, Inc. Stent with protruding branch portion for bifurcated vessels
US6835203B1 (en) 1996-11-04 2004-12-28 Advanced Stent Technologies, Inc. Extendible stent apparatus
US6136007A (en) * 1997-04-17 2000-10-24 St. Jude Medical Cardiovascular Group, Inc, Apparatus for handling tubing used in medical procedures
US5976178A (en) * 1996-11-07 1999-11-02 Vascular Science Inc. Medical grafting methods
US5749890A (en) * 1996-12-03 1998-05-12 Shaknovich; Alexander Method and system for stent placement in ostial lesions
US6071286A (en) * 1997-02-19 2000-06-06 Mawad; Michel E. Combination angioplasty balloon/stent deployment device
US5851210A (en) * 1997-03-21 1998-12-22 Torossian; Richard Stent delivery system and method
GB9706766D0 (en) * 1997-04-03 1997-05-21 Sulzer Vascutek Ltd Endovascular prostheses
US6143016A (en) * 1997-04-21 2000-11-07 Advanced Cardiovascular Systems, Inc. Sheath and method of use for a stent delivery system
US7955379B2 (en) 1997-08-13 2011-06-07 Abbott Cardiovascular Systems Inc. Stent and catheter assembly and method for treating bifurcations
US5948017A (en) * 1997-10-12 1999-09-07 Taheri; Syde A. Modular graft assembly
US6013085A (en) * 1997-11-07 2000-01-11 Howard; John Method for treating stenosis of the carotid artery
US20050171478A1 (en) * 1998-01-13 2005-08-04 Selmon Matthew R. Catheter system for crossing total occlusions in vasculature
US6231546B1 (en) 1998-01-13 2001-05-15 Lumend, Inc. Methods and apparatus for crossing total occlusions in blood vessels
US6129756A (en) * 1998-03-16 2000-10-10 Teramed, Inc. Biluminal endovascular graft system
US6224609B1 (en) 1998-03-16 2001-05-01 Teramed Inc. Bifurcated prosthetic graft
GB2335744A (en) * 1998-03-27 1999-09-29 Intravascular Res Ltd Medical ultrasonic imaging
US6136011A (en) * 1998-07-14 2000-10-24 Advanced Cardiovascular Systems, Inc. Stent delivery system and method of use
US6325824B2 (en) 1998-07-22 2001-12-04 Advanced Cardiovascular Systems, Inc. Crush resistant stent
NL1009738C2 (en) * 1998-07-24 2000-01-25 Cordis Europ Balloon catheter filling body having for the placing of a stent.
US6196230B1 (en) 1998-09-10 2001-03-06 Percardia, Inc. Stent delivery system and method of use
US6261304B1 (en) 1998-09-10 2001-07-17 Percardia, Inc. Delivery methods for left ventricular conduit
EP1669042A3 (en) 1998-09-10 2006-06-28 Percardia, Inc. TMR shunt
WO2000015147A1 (en) 1998-09-10 2000-03-23 Percardia, Inc. Transmycardial shunt and its attachment mechanism, for left ventricular revascularization
US6217527B1 (en) 1998-09-30 2001-04-17 Lumend, Inc. Methods and apparatus for crossing vascular occlusions
US6273909B1 (en) 1998-10-05 2001-08-14 Teramed Inc. Endovascular graft system
US6071287A (en) * 1998-12-23 2000-06-06 Medtronic, Inc. Introducer for single operator stent delivery system
US7344557B2 (en) 2003-11-12 2008-03-18 Advanced Stent Technologies, Inc. Catheter balloon systems and methods
US6375676B1 (en) 1999-05-17 2002-04-23 Advanced Cardiovascular Systems, Inc. Self-expanding stent with enhanced delivery precision and stent delivery system
US8617231B2 (en) 2001-05-18 2013-12-31 Boston Scientific Scimed, Inc. Dual guidewire exchange catheter system
US6638237B1 (en) 1999-08-04 2003-10-28 Percardia, Inc. Left ventricular conduits and methods for delivery
US6302892B1 (en) 1999-08-04 2001-10-16 Percardia, Inc. Blood flow conduit delivery system and method of use
US6183493B1 (en) 1999-08-24 2001-02-06 Pharmasys International, Llc Method and apparatus for the treatment of sleep apnea and related breathing disorders
US6559934B1 (en) * 1999-09-14 2003-05-06 Visx, Incorporated Method and apparatus for determining characteristics of a laser beam spot
US6689156B1 (en) 1999-09-23 2004-02-10 Advanced Stent Technologies, Inc. Stent range transducers and methods of use
US6383171B1 (en) * 1999-10-12 2002-05-07 Allan Will Methods and devices for protecting a passageway in a body when advancing devices through the passageway
US6287291B1 (en) 1999-11-09 2001-09-11 Advanced Cardiovascular Systems, Inc. Protective sheath for catheters
US6443979B1 (en) 1999-12-20 2002-09-03 Advanced Cardiovascular Systems, Inc. Expandable stent delivery sheath and method of use
US6602280B2 (en) 2000-02-02 2003-08-05 Trivascular, Inc. Delivery system and method for expandable intracorporeal device
US20040098085A1 (en) * 2000-02-11 2004-05-20 Ricci Donald R. Stent delivery system and method of use
US6849077B2 (en) 2000-02-11 2005-02-01 Evysio Medical Devices Ulc Stent delivery system and method of use
US6702843B1 (en) 2000-04-12 2004-03-09 Scimed Life Systems, Inc. Stent delivery means with balloon retraction means
US6854467B2 (en) 2000-05-04 2005-02-15 Percardia, Inc. Methods and devices for delivering a ventricular stent
US6649030B1 (en) 2000-08-31 2003-11-18 Endovascular Technologies, Inc. Physical vapor deposition of radiopaque markings on a graft
US6690970B1 (en) 2000-10-06 2004-02-10 Syde A. Taheri Biological pacemaker and implantation catheter
AU3515902A (en) * 2000-12-05 2002-06-18 Lumend Inc Catheter system for vascular re-entry from a sub-intimal space
US6567704B2 (en) * 2000-12-20 2003-05-20 Medtronic, Inc. Medical electrical lead and method of use
US7285097B2 (en) * 2001-01-12 2007-10-23 Radi Medical System Ab Technique to confirm correct positioning with respect to arterial wall
CA2462509A1 (en) 2001-10-04 2003-04-10 Neovasc Medical Ltd. Flow reducing implant
US6761733B2 (en) 2001-04-11 2004-07-13 Trivascular, Inc. Delivery system and method for bifurcated endovascular graft
US6733521B2 (en) 2001-04-11 2004-05-11 Trivascular, Inc. Delivery system and method for endovascular graft
US20050021123A1 (en) 2001-04-30 2005-01-27 Jurgen Dorn Variable speed self-expanding stent delivery system and luer locking connector
AU2002315223A1 (en) * 2001-06-19 2003-01-02 Eva Corporation Positioning apparatus for use in repairing a vessel
JP4350515B2 (en) 2001-11-09 2009-10-21 ルビコン・メデイカル・インコーポレイテツド Stent delivery system
US20100016943A1 (en) 2001-12-20 2010-01-21 Trivascular2, Inc. Method of delivering advanced endovascular graft
US7235095B2 (en) * 2002-02-22 2007-06-26 Scimed Life Systems, Inc. Method and system for deploying multi-part endoluminal devices
US7004964B2 (en) * 2002-02-22 2006-02-28 Scimed Life Systems, Inc. Apparatus and method for deployment of an endoluminal device
US7887573B2 (en) * 2002-02-22 2011-02-15 Boston Scientific Scimed, Inc. Method and apparatus for deployment of an endoluminal device
ITMO20020152A1 (en) * 2002-06-05 2003-12-05 Mariangela Moggi A device for clamping of large vessels
JP2006526464A (en) 2003-06-05 2006-11-24 フローメディカ,インコーポレイテッド System and method for bilateral intervention or diagnostic in branched body lumens
WO2004030718A2 (en) 2002-09-20 2004-04-15 Flowmedica, Inc. Method and apparatus for intra aortic substance delivery to a branch vessel
US7993325B2 (en) * 2002-09-20 2011-08-09 Angio Dynamics, Inc. Renal infusion systems and methods
JP2006508776A (en) 2002-09-20 2006-03-16 フローメディカ,インコーポレイテッド Method and apparatus for selective material delivery via renal catheter
US20060058866A1 (en) * 2003-01-17 2006-03-16 Cully Edward H Deployment system for an expandable device
US7753945B2 (en) * 2003-01-17 2010-07-13 Gore Enterprise Holdings, Inc. Deployment system for an endoluminal device
US7198636B2 (en) 2003-01-17 2007-04-03 Gore Enterprise Holdings, Inc. Deployment system for an endoluminal device
WO2004093745A1 (en) * 2003-04-23 2004-11-04 Cook Incorporated Devices kits, and methods for placing multiple intraluminal medical devices in a body vessel
US20050033416A1 (en) * 2003-05-02 2005-02-10 Jacques Seguin Vascular graft and deployment system
US7947070B2 (en) * 2003-05-16 2011-05-24 Boston Scientific Scimed, Inc. Dilatation and stent delivery system and related methods
EP2286771B1 (en) * 2003-05-23 2016-05-11 Boston Scientific Limited Stents with attached looped ends
CA2526276C (en) * 2003-05-23 2011-05-03 Kabushikikaisha Igaki Iryo Sekkei Stent supplying device
US20050004647A1 (en) * 2003-07-03 2005-01-06 William Cook Europe Aps Hybrid stent apparatus
US7655030B2 (en) 2003-07-18 2010-02-02 Boston Scientific Scimed, Inc. Catheter balloon systems and methods
US8535344B2 (en) 2003-09-12 2013-09-17 Rubicon Medical, Inc. Methods, systems, and devices for providing embolic protection and removing embolic material
US7699865B2 (en) 2003-09-12 2010-04-20 Rubicon Medical, Inc. Actuating constraining mechanism
CA2544416A1 (en) * 2003-11-03 2005-05-12 B-Balloon Ltd. Treatment of vascular bifurcations
US7258697B1 (en) 2003-12-22 2007-08-21 Advanced Cardiovascular Systems, Inc. Stent with anchors to prevent vulnerable plaque rupture during deployment
US20050154441A1 (en) * 2004-01-14 2005-07-14 Cook Incorporated Introducer
US20050197624A1 (en) 2004-03-04 2005-09-08 Flowmedica, Inc. Sheath for use in peripheral interventions
JP2007537298A (en) * 2004-05-14 2007-12-20 フロウメディカ, インコーポレイテッド Bilateral local renal delivery for the treatment and bnp therapy of congestive heart failure
JP2008518710A (en) * 2004-11-03 2008-06-05 セガン,ジャック Vascular grafts and deployment system
US8337543B2 (en) 2004-11-05 2012-12-25 Boston Scientific Scimed, Inc. Prosthesis anchoring and deploying device
US8562566B2 (en) * 2005-02-28 2013-10-22 Boston Scientific Scimed, Inc. Stent delivery and guidewire guidance system
US7763198B2 (en) 2005-04-12 2010-07-27 Abbott Cardiovascular Systems Inc. Method for retaining a vascular stent on a catheter
US7947207B2 (en) 2005-04-12 2011-05-24 Abbott Cardiovascular Systems Inc. Method for retaining a vascular stent on a catheter
JP2009504345A (en) 2005-08-17 2009-02-05 シー・アール・バード・インコーポレーテッドC R Bard Incorporated Variable speed stent delivery system
US20070061001A1 (en) * 2005-09-13 2007-03-15 Advanced Cardiovascular Systems, Inc. Packaging sheath for drug coated stent
JP2009508622A (en) * 2005-09-21 2009-03-05 ビー−バルーン リミティド Branch balloon and stent
JP5184371B2 (en) * 2005-12-29 2013-04-17 ダブリュー.エル.ゴア アンド アソシエイツ,インコーポレイテッド Syringe activated valve and method for flash catheter
EP2727564A1 (en) 2006-01-13 2014-05-07 C. R. Bard, Inc. Stent delivery system
US20070185524A1 (en) * 2006-02-03 2007-08-09 Pedro Diaz Rapid exchange emboli capture guidewire system and methods of use
US8821561B2 (en) 2006-02-22 2014-09-02 Boston Scientific Scimed, Inc. Marker arrangement for bifurcation catheter
US7771401B2 (en) 2006-06-08 2010-08-10 Angiodynamics, Inc. Selective renal cannulation and infusion systems and methods
US20070288036A1 (en) * 2006-06-09 2007-12-13 Niranjan Seshadri Assembly for crossing a chronic total occlusion and method therefor
GB0615658D0 (en) 2006-08-07 2006-09-13 Angiomed Ag Hand-held actuator device
US9364586B2 (en) 2007-05-31 2016-06-14 Abbott Cardiovascular Systems Inc. Method and apparatus for improving delivery of an agent to a kidney
US8216209B2 (en) 2007-05-31 2012-07-10 Abbott Cardiovascular Systems Inc. Method and apparatus for delivering an agent to a kidney
US9149610B2 (en) 2007-05-31 2015-10-06 Abbott Cardiovascular Systems Inc. Method and apparatus for improving delivery of an agent to a kidney
US9144509B2 (en) 2007-05-31 2015-09-29 Abbott Cardiovascular Systems Inc. Method and apparatus for delivering an agent to a kidney
GB0713497D0 (en) 2007-07-11 2007-08-22 Angiomed Ag Device for catheter sheath retraction
US8486134B2 (en) 2007-08-01 2013-07-16 Boston Scientific Scimed, Inc. Bifurcation treatment system and methods
US20090163851A1 (en) * 2007-12-19 2009-06-25 Holloway Kenneth A Occlusive material removal device having selectively variable stiffness
WO2009088953A2 (en) 2007-12-31 2009-07-16 Boston Scientific Scimed Inc. Bifurcation stent delivery system and methods
US8377108B2 (en) 2008-06-02 2013-02-19 Boston Scientific Scimed, Inc. Staggered two balloon bifurcation catheter assembly and methods
JP5662310B2 (en) 2008-06-05 2015-01-28 ボストン サイエンティフィック サイムド,インコーポレイテッドBoston Scientific Scimed,Inc. Shrinkable branch device and manufacturing method thereof
EP2299945B1 (en) 2008-06-05 2016-03-23 Boston Scientific Scimed, Inc. Balloon bifurcated lumen treatment
US8049061B2 (en) 2008-09-25 2011-11-01 Abbott Cardiovascular Systems, Inc. Expandable member formed of a fibrous matrix having hydrogel polymer for intraluminal drug delivery
US8226603B2 (en) 2008-09-25 2012-07-24 Abbott Cardiovascular Systems Inc. Expandable member having a covering formed of a fibrous matrix for intraluminal drug delivery
US8500687B2 (en) 2008-09-25 2013-08-06 Abbott Cardiovascular Systems Inc. Stent delivery system having a fibrous matrix covering with improved stent retention
US8076529B2 (en) 2008-09-26 2011-12-13 Abbott Cardiovascular Systems, Inc. Expandable member formed of a fibrous matrix for intraluminal drug delivery
US20100145429A1 (en) * 2008-12-09 2010-06-10 Cook Incorporated Introducer sheath and method of manufacture
WO2010150208A2 (en) 2009-06-23 2010-12-29 Endospan Ltd. Vascular prostheses for treating aneurysms
US8979892B2 (en) 2009-07-09 2015-03-17 Endospan Ltd. Apparatus for closure of a lumen and methods of using the same
AU2010308367A1 (en) * 2009-10-19 2012-05-17 Cook Medical Technologies Llc Balloon-tipped endoscopic system with inverted sleeve
US9468517B2 (en) 2010-02-08 2016-10-18 Endospan Ltd. Thermal energy application for prevention and management of endoleaks in stent-grafts
US20110208289A1 (en) * 2010-02-25 2011-08-25 Endospan Ltd. Flexible Stent-Grafts
GB201017834D0 (en) 2010-10-21 2010-12-01 Angiomed Ag System to deliver a bodily implant
FR2970864B1 (en) * 2011-02-01 2015-01-02 Stentys issuance of a stent system
WO2012104842A2 (en) * 2011-02-03 2012-08-09 Endospan Ltd. Implantable medical devices constructed of shape memory material
US9101507B2 (en) 2011-05-18 2015-08-11 Ralph F. Caselnova Apparatus and method for proximal-to-distal endoluminal stent deployment
US9254209B2 (en) 2011-07-07 2016-02-09 Endospan Ltd. Stent fixation with reduced plastic deformation
US9839510B2 (en) 2011-08-28 2017-12-12 Endospan Ltd. Stent-grafts with post-deployment variable radial displacement
US9427339B2 (en) 2011-10-30 2016-08-30 Endospan Ltd. Triple-collar stent-graft
US9204966B2 (en) * 2011-11-21 2015-12-08 Northwestern University Penile prosthesis
WO2013084235A2 (en) 2011-12-04 2013-06-13 Endospan Ltd. Branched stent-graft system
US9393140B2 (en) * 2012-04-27 2016-07-19 Medtronic Vascular, Inc. Reconfigurable stent-graft delivery system and method of use
US9770350B2 (en) 2012-05-15 2017-09-26 Endospan Ltd. Stent-graft with fixation elements that are radially confined for delivery
CN105246537A (en) * 2013-03-15 2016-01-13 雅培心血管系统有限公司 Length adjustable balloon catheter for multiple indications
US20150105816A1 (en) * 2013-10-14 2015-04-16 Timothy Rasmusson Multiple balloon venous occlusion catheter
US9668899B2 (en) 2014-03-27 2017-06-06 Clever Cath Technologies, LLC Rapid exchange sheathless predilatation angioplasty and stent deployment catheter
US9387102B2 (en) 2014-03-27 2016-07-12 Clever Cath Technologies, LLC Sheathless predilatation angioplasty and stent deployment catheter
US10130465B2 (en) 2016-02-23 2018-11-20 Abbott Cardiovascular Systems Inc. Bifurcated tubular graft for treating tricuspid regurgitation

Citations (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US832201A (en) * 1904-12-12 1906-10-02 Samuel L Kistler Dilator.
US1737488A (en) * 1928-12-06 1929-11-26 John P Zohlen Dilator
US2684069A (en) * 1952-07-05 1954-07-20 Donaldson Precision linear-fracture instrument for heart valve surgery
US3495586A (en) * 1965-07-28 1970-02-17 Eberhard Regenbogen Rectoscope with spreading means
US3517128A (en) * 1968-02-08 1970-06-23 James R Hines Surgical expanding arm dilator
US3557794A (en) * 1968-07-30 1971-01-26 Us Air Force Arterial dilation device
US3657744A (en) * 1970-05-08 1972-04-25 Univ Minnesota Method for fixing prosthetic implants in a living body
US3704712A (en) * 1970-04-10 1972-12-05 Medidyne Corp Dilator device
US3968800A (en) * 1974-09-17 1976-07-13 Vilasi Joseph A Device for insertion into a body opening
US3996938A (en) * 1975-07-10 1976-12-14 Clark Iii William T Expanding mesh catheter
US4168709A (en) * 1975-03-10 1979-09-25 Bentov Itzhak E Dilator
US4299226A (en) * 1979-08-08 1981-11-10 Banka Vidya S Coronary dilation method
US4320762A (en) * 1975-03-10 1982-03-23 Bentov Itzhak E Dilator
US4577631A (en) * 1984-11-16 1986-03-25 Kreamer Jeffry W Aneurysm repair apparatus and method
US4585000A (en) * 1983-09-28 1986-04-29 Cordis Corporation Expandable device for treating intravascular stenosis
US4648402A (en) * 1985-10-03 1987-03-10 Santos Manuel V Blood vessel dilating surgical instrument
US4655771A (en) * 1982-04-30 1987-04-07 Shepherd Patents S.A. Prosthesis comprising an expansible or contractile tubular body
US4787899A (en) * 1983-12-09 1988-11-29 Lazarus Harrison M Intraluminal graft device, system and method
US4921484A (en) * 1988-07-25 1990-05-01 Cordis Corporation Mesh balloon catheter device
US4969890A (en) * 1987-07-10 1990-11-13 Nippon Zeon Co., Ltd. Catheter
US4990155A (en) * 1989-05-19 1991-02-05 Wilkoff Howard M Surgical stent method and apparatus
US4990151A (en) * 1988-09-28 1991-02-05 Medinvent S.A. Device for transluminal implantation or extraction
US5064434A (en) * 1990-04-04 1991-11-12 Haber Terry M Genitourinary implant
US5074871A (en) * 1989-12-07 1991-12-24 Evi Corporation Catheter atherotome
US5108416A (en) * 1990-02-13 1992-04-28 C. R. Bard, Inc. Stent introducer system
US5190058A (en) * 1991-05-22 1993-03-02 Medtronic, Inc. Method of using a temporary stent catheter
US5221258A (en) * 1991-01-22 1993-06-22 Shturman Technologies, Inc. Introduction balloon catheter
US5226889A (en) * 1990-07-30 1993-07-13 Imad Sheiban Double balloon catheter for stent implantation
EP0551179A1 (en) * 1992-01-08 1993-07-14 Expandable Grafts Partnership Method and apparatus for bilateral intra-aortic bypass
US5266073A (en) * 1987-12-08 1993-11-30 Wall W Henry Angioplasty stent
US5275622A (en) * 1983-12-09 1994-01-04 Harrison Medical Technologies, Inc. Endovascular grafting apparatus, system and method and devices for use therewith
EP0596145A1 (en) * 1992-10-31 1994-05-11 Schneider (Europe) Ag Disposition for implanting a self-expanding endoprothesis
US5324262A (en) * 1993-02-09 1994-06-28 Cathco, Inc. Introducer sheath with expandable outer tube and method of use
EP0505686B1 (en) * 1991-01-28 1996-11-13 Advanced Cardiovascular Systems, Inc. Stent delivery system

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1322628C (en) * 1988-10-04 1993-10-05 Richard A. Schatz Expandable intraluminal graft
EP0461791B1 (en) * 1990-06-11 1997-01-02 Hector D. Barone Aortic graft and apparatus for repairing an abdominal aortic aneurysm
US5626605A (en) * 1991-12-30 1997-05-06 Scimed Life Systems, Inc. Thrombosis filter

Patent Citations (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US832201A (en) * 1904-12-12 1906-10-02 Samuel L Kistler Dilator.
US1737488A (en) * 1928-12-06 1929-11-26 John P Zohlen Dilator
US2684069A (en) * 1952-07-05 1954-07-20 Donaldson Precision linear-fracture instrument for heart valve surgery
US3495586A (en) * 1965-07-28 1970-02-17 Eberhard Regenbogen Rectoscope with spreading means
US3517128A (en) * 1968-02-08 1970-06-23 James R Hines Surgical expanding arm dilator
US3557794A (en) * 1968-07-30 1971-01-26 Us Air Force Arterial dilation device
US3704712A (en) * 1970-04-10 1972-12-05 Medidyne Corp Dilator device
US3657744A (en) * 1970-05-08 1972-04-25 Univ Minnesota Method for fixing prosthetic implants in a living body
US3968800A (en) * 1974-09-17 1976-07-13 Vilasi Joseph A Device for insertion into a body opening
US4168709A (en) * 1975-03-10 1979-09-25 Bentov Itzhak E Dilator
US4320762A (en) * 1975-03-10 1982-03-23 Bentov Itzhak E Dilator
US3996938A (en) * 1975-07-10 1976-12-14 Clark Iii William T Expanding mesh catheter
US4299226A (en) * 1979-08-08 1981-11-10 Banka Vidya S Coronary dilation method
US4655771B1 (en) * 1982-04-30 1996-09-10 Medinvent Ams Sa Prosthesis comprising an expansible or contractile tubular body
US4655771A (en) * 1982-04-30 1987-04-07 Shepherd Patents S.A. Prosthesis comprising an expansible or contractile tubular body
US4585000A (en) * 1983-09-28 1986-04-29 Cordis Corporation Expandable device for treating intravascular stenosis
US5275622A (en) * 1983-12-09 1994-01-04 Harrison Medical Technologies, Inc. Endovascular grafting apparatus, system and method and devices for use therewith
US4787899A (en) * 1983-12-09 1988-11-29 Lazarus Harrison M Intraluminal graft device, system and method
US4577631A (en) * 1984-11-16 1986-03-25 Kreamer Jeffry W Aneurysm repair apparatus and method
US4648402A (en) * 1985-10-03 1987-03-10 Santos Manuel V Blood vessel dilating surgical instrument
US4969890A (en) * 1987-07-10 1990-11-13 Nippon Zeon Co., Ltd. Catheter
US5266073A (en) * 1987-12-08 1993-11-30 Wall W Henry Angioplasty stent
US4921484A (en) * 1988-07-25 1990-05-01 Cordis Corporation Mesh balloon catheter device
US4990151A (en) * 1988-09-28 1991-02-05 Medinvent S.A. Device for transluminal implantation or extraction
US4990155A (en) * 1989-05-19 1991-02-05 Wilkoff Howard M Surgical stent method and apparatus
US5074871A (en) * 1989-12-07 1991-12-24 Evi Corporation Catheter atherotome
US5108416A (en) * 1990-02-13 1992-04-28 C. R. Bard, Inc. Stent introducer system
US5064434A (en) * 1990-04-04 1991-11-12 Haber Terry M Genitourinary implant
US5226889A (en) * 1990-07-30 1993-07-13 Imad Sheiban Double balloon catheter for stent implantation
US5221258A (en) * 1991-01-22 1993-06-22 Shturman Technologies, Inc. Introduction balloon catheter
EP0505686B1 (en) * 1991-01-28 1996-11-13 Advanced Cardiovascular Systems, Inc. Stent delivery system
US5190058A (en) * 1991-05-22 1993-03-02 Medtronic, Inc. Method of using a temporary stent catheter
EP0551179A1 (en) * 1992-01-08 1993-07-14 Expandable Grafts Partnership Method and apparatus for bilateral intra-aortic bypass
EP0596145A1 (en) * 1992-10-31 1994-05-11 Schneider (Europe) Ag Disposition for implanting a self-expanding endoprothesis
US5324262A (en) * 1993-02-09 1994-06-28 Cathco, Inc. Introducer sheath with expandable outer tube and method of use

Cited By (193)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6575994B1 (en) 1994-02-10 2003-06-10 Teramed, Inc. Method and apparatus concerning bypass grafts
US5788708A (en) * 1996-09-20 1998-08-04 Intella Interventional Systems, Inc. Multiple balloon stent delivery catheter and method
US6432127B1 (en) 1996-10-11 2002-08-13 Transvascular, Inc. Devices for forming and/or maintaining connections between adjacent anatomical conduits
US6210422B1 (en) 1997-02-20 2001-04-03 Endologix, Inc. Bifurcated vascular graft deployment device
US6156063A (en) * 1997-02-20 2000-12-05 Endologix, Inc. Method of deploying bifurcated vascular graft
US6152945A (en) * 1997-04-23 2000-11-28 St. Jude Medical Cardiovascular Group, Inc. Tubular medical graft connectors
US6293965B1 (en) 1997-04-23 2001-09-25 St. Jude Medical Anastomotic Technology Group, Inc. Tubular medical graft connectors
US6451033B1 (en) 1997-04-23 2002-09-17 St. Jude Medical Atg, Inc. Tubular medical graft connectors
US6478813B1 (en) 1997-08-01 2002-11-12 Peter T. Keith Method for joining grafts in a common body passageway
US6174327B1 (en) 1998-02-27 2001-01-16 Scimed Life Systems, Inc. Stent deployment apparatus and method
US6331190B1 (en) 1998-03-04 2001-12-18 Endologix, Inc. Endoluminal vascular prosthesis
US6482227B1 (en) 1998-03-30 2002-11-19 Cordis Corporation Stent graft having improved attachment within a body vessel
US5944727A (en) * 1998-09-02 1999-08-31 Datascope Investment Corp. Stent/graft catheter handle
US6514261B1 (en) 1998-09-30 2003-02-04 Impra, Inc. Delivery mechanism for implantable stent
US8852266B2 (en) 1998-09-30 2014-10-07 Bard Peripheral Vascular, Inc. Delivery mechanism for implantable stent
US7122050B2 (en) 1998-09-30 2006-10-17 Bard Peripheral Vascular, Inc. Delivery mechanism for implantable stent
US6733523B2 (en) 1998-12-11 2004-05-11 Endologix, Inc. Implantable vascular graft
US6500202B1 (en) 1998-12-11 2002-12-31 Endologix, Inc. Bifurcation graft deployment catheter
US6508835B1 (en) 1998-12-11 2003-01-21 Endologix, Inc. Endoluminal vascular prosthesis
US8147535B2 (en) 1998-12-11 2012-04-03 Endologix, Inc. Bifurcation graft deployment catheter
US6660030B2 (en) 1998-12-11 2003-12-09 Endologix, Inc. Bifurcation graft deployment catheter
US6656201B2 (en) 1998-12-15 2003-12-02 Micrus Corporation Variable stiffness coil for vasoocclusive devices
US6383204B1 (en) 1998-12-15 2002-05-07 Micrus Corporation Variable stiffness coil for vasoocclusive devices
US8034100B2 (en) 1999-03-11 2011-10-11 Endologix, Inc. Graft deployment system
US8167925B2 (en) 1999-03-11 2012-05-01 Endologix, Inc. Single puncture bifurcation graft deployment system
US6190360B1 (en) 1999-04-09 2001-02-20 Endotex Interventional System Stent delivery handle
US6231496B1 (en) * 1999-07-07 2001-05-15 Peter J. Wilk Medical treatment method
US9327068B2 (en) 1999-09-03 2016-05-03 Maquet Cardiovascular Llc Guidable intravascular blood pump and related methods
US9545468B2 (en) 1999-09-03 2017-01-17 Maquet Cardiovascular Llc Guidable intravascular blood pump and related methods
US9789238B2 (en) 1999-09-03 2017-10-17 Maquet Cardiovascular, Llc Guidable intravascular blood pump and related methods
US10238783B2 (en) 1999-09-03 2019-03-26 Maquet Cardiovascular Llc Guidable intravascular blood pump and related methods
US9597437B2 (en) 1999-09-03 2017-03-21 Maquet Cardiovascular Llc Guidable intravascular blood pump and related methods
US9561314B2 (en) 1999-09-03 2017-02-07 Maquet Cardiovascular Llc Guidable intravascular blood pump and related methods
US20020173785A1 (en) * 2000-03-31 2002-11-21 Medtronic, Inc. System and method for positioning implantable medical devices within coronary veins
US6733500B2 (en) 2000-03-31 2004-05-11 Medtronic, Inc. Method and system for delivering a medical electrical lead within a venous system
US8734397B2 (en) 2000-03-31 2014-05-27 Medtronic, Inc. System and method for positioning implantable medical devices within coronary veins
US7497844B2 (en) 2000-03-31 2009-03-03 Medtronic, Inc. System and method for positioning implantable medical devices within coronary veins
US20090131873A1 (en) * 2000-03-31 2009-05-21 Medtronic, Inc. System and method for positioning implantable medical devices within coronary veins
US6533782B2 (en) 2000-05-18 2003-03-18 Wilson-Cook Medical Incorporated Medical device with improved wire guide access
US7819882B2 (en) 2000-07-10 2010-10-26 Boston Scientific Cupertino Corporation Stent delivery device
US20060167467A1 (en) * 2000-07-10 2006-07-27 Endotex Interventional Systems, Inc. Stent delivery device
US6527779B1 (en) 2000-07-10 2003-03-04 Endotex Interventional Systems, Inc. Stent delivery device
US6773446B1 (en) 2000-08-02 2004-08-10 Cordis Corporation Delivery apparatus for a self-expanding stent
US6743219B1 (en) 2000-08-02 2004-06-01 Cordis Corporation Delivery apparatus for a self-expanding stent
US20020193863A1 (en) * 2000-09-18 2002-12-19 Endotex Interventional Systems, Inc. Apparatus for delivering endoluminal prosthesis and methods for preparing such apparatus for delivery
US6945989B1 (en) 2000-09-18 2005-09-20 Endotex Interventional Systems, Inc. Apparatus for delivering endoluminal prostheses and methods of making and using them
US6602226B1 (en) 2000-10-12 2003-08-05 Scimed Life Systems, Inc. Low-profile stent delivery system and apparatus
US6626938B1 (en) 2000-11-16 2003-09-30 Cordis Corporation Stent graft having a pleated graft member
US7862609B2 (en) 2000-11-16 2011-01-04 Cordis Corporation Stent graft having a pleated graft member
US8147536B2 (en) 2001-03-29 2012-04-03 Xtent, Inc. Balloon catheter for multiple adjustable stent deployment
US9980839B2 (en) 2001-03-29 2018-05-29 J.W. Medical Systems Ltd. Balloon catheter for multiple adjustable stent deployment
US8142487B2 (en) 2001-03-29 2012-03-27 Xtent, Inc. Balloon catheter for multiple adjustable stent deployment
US9119739B2 (en) 2001-03-29 2015-09-01 J.W. Medical Systems Ltd. Balloon catheter for multiple adjustable stent deployment
US20040034383A1 (en) * 2001-07-31 2004-02-19 Amir Belson Flow-directed catheter guide with variable rigidity shaft
US20100010441A1 (en) * 2001-07-31 2010-01-14 Amir Belson Flow-directed catheter guide with variable rigidity shaft
US8257427B2 (en) 2001-09-11 2012-09-04 J.W. Medical Systems, Ltd. Expandable stent
US7182779B2 (en) 2001-12-03 2007-02-27 Xtent, Inc. Apparatus and methods for positioning prostheses for deployment from a catheter
US9326876B2 (en) 2001-12-03 2016-05-03 J.W. Medical Systems Ltd. Apparatus and methods for delivery of multiple distributed stents
US8702781B2 (en) 2001-12-03 2014-04-22 J.W. Medical Systems Ltd. Apparatus and methods for delivery of multiple distributed stents
US8083788B2 (en) 2001-12-03 2011-12-27 Xtent, Inc. Apparatus and methods for positioning prostheses for deployment from a catheter
US7147656B2 (en) 2001-12-03 2006-12-12 Xtent, Inc. Apparatus and methods for delivery of braided prostheses
US20070088368A1 (en) * 2001-12-03 2007-04-19 Xtent, Inc. Apparatus and methods for delivery of multiple distributed stents
US20040093061A1 (en) * 2001-12-03 2004-05-13 Xtent, Inc. A Delaware Corporation Apparatus and methods for delivery of multiple distributed stents
US7137993B2 (en) 2001-12-03 2006-11-21 Xtent, Inc. Apparatus and methods for delivery of multiple distributed stents
US8070789B2 (en) 2001-12-03 2011-12-06 Xtent, Inc. Apparatus and methods for deployment of vascular prostheses
US7270668B2 (en) 2001-12-03 2007-09-18 Xtent, Inc. Apparatus and methods for delivering coiled prostheses
US7294146B2 (en) 2001-12-03 2007-11-13 Xtent, Inc. Apparatus and methods for delivery of variable length stents
US8574282B2 (en) 2001-12-03 2013-11-05 J.W. Medical Systems Ltd. Apparatus and methods for delivery of braided prostheses
US7309350B2 (en) 2001-12-03 2007-12-18 Xtent, Inc. Apparatus and methods for deployment of vascular prostheses
US8016871B2 (en) 2001-12-03 2011-09-13 Xtent, Inc. Apparatus and methods for delivery of multiple distributed stents
US7351255B2 (en) 2001-12-03 2008-04-01 Xtent, Inc. Stent delivery apparatus and method
US7357812B2 (en) 2001-12-03 2008-04-15 Xtent, Inc. Apparatus and methods for delivery of braided prostheses
US8080048B2 (en) 2001-12-03 2011-12-20 Xtent, Inc. Stent delivery for bifurcated vessels
US7922755B2 (en) 2001-12-03 2011-04-12 Xtent, Inc. Apparatus and methods for delivery of multiple distributed stents
US20040215331A1 (en) * 2001-12-03 2004-10-28 Xtent, Inc. Apparatus and methods for delivery of variable length stents
US8016870B2 (en) 2001-12-03 2011-09-13 Xtent, Inc. Apparatus and methods for delivery of variable length stents
US20050010276A1 (en) * 2001-12-03 2005-01-13 Xtent, Inc. Apparatus and methods for positioning prostheses for deployment from a catheter
US20030135258A1 (en) * 2001-12-03 2003-07-17 Xtent, Inc. Apparatus and methods for delivery of braided prostheses
US20050049673A1 (en) * 2001-12-03 2005-03-03 Xtent, Inc. A Delaware Corporation Apparatus and methods for delivery of braided prostheses
US7905913B2 (en) 2001-12-03 2011-03-15 Xtent, Inc. Apparatus and methods for delivery of multiple distributed stents
US7892273B2 (en) 2001-12-03 2011-02-22 Xtent, Inc. Custom length stent apparatus
US7892274B2 (en) 2001-12-03 2011-02-22 Xtent, Inc. Apparatus and methods for deployment of vascular prostheses
US8177831B2 (en) 2001-12-03 2012-05-15 Xtent, Inc. Stent delivery apparatus and method
US8956398B2 (en) 2001-12-03 2015-02-17 J.W. Medical Systems Ltd. Custom length stent apparatus
US7938852B2 (en) 2001-12-03 2011-05-10 Xtent, Inc. Apparatus and methods for delivery of braided prostheses
US7169170B2 (en) 2002-02-22 2007-01-30 Cordis Corporation Self-expanding stent delivery system
US20060135340A1 (en) * 2002-07-30 2006-06-22 Cheang Hong N P Spherical nano-composite powder and a method of preparing the same
US20050256092A1 (en) * 2002-08-01 2005-11-17 Shin Shimaoka Antipsoriatic agent
US20040111145A1 (en) * 2002-11-27 2004-06-10 Francesco Serino Vascular prosthesis for the treatment of abdominal aortic aneurysms, using a combined laparoscopic/ open and endovascular technique, and delivery system for releasing a prosthesis fitted with anchoring stents
US7235094B2 (en) * 2002-11-27 2007-06-26 Bolton Medical, Inc. Vascular prosthesis for the treatment of abdominal aortic aneurysms, using a combined laparoscopic/open and endovascular technique, and delivery system for releasing a prosthesis fitted with anchoring stents
US20100016939A1 (en) * 2002-11-27 2010-01-21 Francesco Serino Vascular Prosthesis for the Treatment of Abdominal Aortic Aneurysms Using A Combined Laparoscopic/Open and Endovascular Technique, and Delivery System For Releasing A Prosthesis Fitted With Anchoring Stents
US8282680B2 (en) 2003-01-17 2012-10-09 J. W. Medical Systems Ltd. Multiple independent nested stent structures and methods for their preparation and deployment
US8740968B2 (en) 2003-01-17 2014-06-03 J.W. Medical Systems Ltd. Multiple independent nested stent structures and methods for their preparation and deployment
US8287582B2 (en) * 2003-04-28 2012-10-16 C. R. Bard, Inc. Loading and delivery of self-expanding stents
US9072623B2 (en) 2003-04-28 2015-07-07 C. R. Bard, Inc. Loading and delivery of self-expanding stents
US20070083256A1 (en) * 2003-04-28 2007-04-12 C.R. Bard, Inc. Loading and delivery of self-expanding stents
US20040249435A1 (en) * 2003-06-09 2004-12-09 Xtent, Inc. Stent deployment systems and methods
US7241308B2 (en) 2003-06-09 2007-07-10 Xtent, Inc. Stent deployment systems and methods
US7918881B2 (en) 2003-06-09 2011-04-05 Xtent, Inc. Stent deployment systems and methods
US20060200223A1 (en) * 2003-06-09 2006-09-07 Xtent, Inc. Stent deployment systems and methods
US20060259123A1 (en) * 2003-09-25 2006-11-16 C. R. Bard, Inc. Lining for bodily lumen
US7717949B2 (en) 2003-09-25 2010-05-18 C. R. Bard, Inc. Lining for bodily lumen
US7553324B2 (en) 2003-10-14 2009-06-30 Xtent, Inc. Fixed stent delivery devices and methods
US7192440B2 (en) 2003-10-15 2007-03-20 Xtent, Inc. Implantable stent delivery devices and methods
US20050085888A1 (en) * 2003-10-15 2005-04-21 Xtent, Inc. Implantable stent delivery devices and methods
US20050125479A1 (en) * 2003-12-08 2005-06-09 Luciano Zoso Hardware for performing an arithmetic function
US8585747B2 (en) 2003-12-23 2013-11-19 J.W. Medical Systems Ltd. Devices and methods for controlling and indicating the length of an interventional element
US7326236B2 (en) 2003-12-23 2008-02-05 Xtent, Inc. Devices and methods for controlling and indicating the length of an interventional element
US9566179B2 (en) 2003-12-23 2017-02-14 J.W. Medical Systems Ltd. Devices and methods for controlling and indicating the length of an interventional element
US20050149159A1 (en) * 2003-12-23 2005-07-07 Xtent, Inc., A Delaware Corporation Devices and methods for controlling and indicating the length of an interventional element
US8333784B2 (en) 2004-02-24 2012-12-18 Boston Scientific Scimed, Inc. Rotatable catheter assembly
US7922740B2 (en) 2004-02-24 2011-04-12 Boston Scientific Scimed, Inc. Rotatable catheter assembly
US7744619B2 (en) 2004-02-24 2010-06-29 Boston Scientific Scimed, Inc. Rotatable catheter assembly
US8460358B2 (en) 2004-03-30 2013-06-11 J.W. Medical Systems, Ltd. Rapid exchange interventional devices and methods
US7300456B2 (en) 2004-06-28 2007-11-27 Xtent, Inc. Custom-length self-expanding stent delivery systems with stent bumpers
US8317859B2 (en) 2004-06-28 2012-11-27 J.W. Medical Systems Ltd. Devices and methods for controlling expandable prostheses during deployment
US8986362B2 (en) 2004-06-28 2015-03-24 J.W. Medical Systems Ltd. Devices and methods for controlling expandable prostheses during deployment
US9700448B2 (en) 2004-06-28 2017-07-11 J.W. Medical Systems Ltd. Devices and methods for controlling expandable prostheses during deployment
US20070005122A1 (en) * 2004-09-24 2007-01-04 Olympus Corporation Treatment instrument installation member, stent delivery catheter and conduit system
US8353944B2 (en) * 2005-03-14 2013-01-15 Boston Scientific Scimed, Inc. Bifurcation delivery system
US20060206188A1 (en) * 2005-03-14 2006-09-14 Jan Weber Bifurcation delivery system
US7402168B2 (en) 2005-04-11 2008-07-22 Xtent, Inc. Custom-length stent delivery system with independently operable expansion elements
US20070118207A1 (en) * 2005-05-04 2007-05-24 Aga Medical Corporation System for controlled delivery of stents and grafts
US20060253184A1 (en) * 2005-05-04 2006-11-09 Kurt Amplatz System for the controlled delivery of stents and grafts
US8652193B2 (en) 2005-05-09 2014-02-18 Angiomed Gmbh & Co. Medizintechnik Kg Implant delivery device
US20060253185A1 (en) * 2005-05-09 2006-11-09 Medtronic Vascular, Inc. Catheter for stent delivery having expanded inner member
US20060271150A1 (en) * 2005-05-31 2006-11-30 Xtent, Inc. In situ stent formation
US8460357B2 (en) 2005-05-31 2013-06-11 J.W. Medical Systems Ltd. In situ stent formation
US20060271151A1 (en) * 2005-05-31 2006-11-30 Xtent, Inc. In situ stent formation
US8641746B2 (en) 2005-05-31 2014-02-04 J.W. Medical Systems Ltd. In situ stent formation
US7938851B2 (en) 2005-06-08 2011-05-10 Xtent, Inc. Devices and methods for operating and controlling interventional apparatus
US8157851B2 (en) 2005-06-08 2012-04-17 Xtent, Inc. Apparatus and methods for deployment of multiple custom-length prostheses
US10219923B2 (en) 2005-06-08 2019-03-05 J.W. Medical Systems Ltd. Apparatus and methods for deployment of multiple custom-length prostheses (III)
US9198784B2 (en) 2005-06-08 2015-12-01 J.W. Medical Systems Ltd. Apparatus and methods for deployment of multiple custom-length prostheses
US9883957B2 (en) 2006-03-20 2018-02-06 J.W. Medical Systems Ltd. Apparatus and methods for deployment of linked prosthetic segments
US8652198B2 (en) 2006-03-20 2014-02-18 J.W. Medical Systems Ltd. Apparatus and methods for deployment of linked prosthetic segments
US8252036B2 (en) 2006-07-31 2012-08-28 Syntheon Cardiology, Llc Sealable endovascular implants and methods for their use
US9138335B2 (en) 2006-07-31 2015-09-22 Syntheon Cardiology, Llc Surgical implant devices and methods for their manufacture and use
US9585743B2 (en) 2006-07-31 2017-03-07 Edwards Lifesciences Cardiaq Llc Surgical implant devices and methods for their manufacture and use
US9827125B2 (en) 2006-07-31 2017-11-28 Edwards Lifesciences Cardiaq Llc Sealable endovascular implants and methods for their use
US8523931B2 (en) 2007-01-12 2013-09-03 Endologix, Inc. Dual concentric guidewire and methods of bifurcated graft deployment
US9457133B2 (en) 2007-02-20 2016-10-04 J.W. Medical Systems Ltd. Thermo-mechanically controlled implants and methods of use
US8980297B2 (en) 2007-02-20 2015-03-17 J.W. Medical Systems Ltd. Thermo-mechanically controlled implants and methods of use
US8486132B2 (en) 2007-03-22 2013-07-16 J.W. Medical Systems Ltd. Devices and methods for controlling expandable prostheses during deployment
US9339404B2 (en) 2007-03-22 2016-05-17 J.W. Medical Systems Ltd. Devices and methods for controlling expandable prostheses during deployment
US9814611B2 (en) 2007-07-31 2017-11-14 Edwards Lifesciences Cardiaq Llc Actively controllable stent, stent graft, heart valve and method of controlling same
US8870908B2 (en) 2007-08-17 2014-10-28 DePuy Synthes Products, LLC Twisted primary coil for vascular therapy
US9101503B2 (en) 2008-03-06 2015-08-11 J.W. Medical Systems Ltd. Apparatus having variable strut length and methods of use
US8236040B2 (en) 2008-04-11 2012-08-07 Endologix, Inc. Bifurcated graft deployment systems and methods
US8357192B2 (en) 2008-04-11 2013-01-22 Endologix, Inc. Bifurcated graft deployment systems and methods
US8764812B2 (en) 2008-04-11 2014-07-01 Endologix, Inc. Bifurcated graft deployment systems and methods
US8216295B2 (en) 2008-07-01 2012-07-10 Endologix, Inc. Catheter system and methods of using same
US9700701B2 (en) 2008-07-01 2017-07-11 Endologix, Inc. Catheter system and methods of using same
US8133199B2 (en) 2008-08-27 2012-03-13 Boston Scientific Scimed, Inc. Electroactive polymer activation system for a medical device
US20100070016A1 (en) * 2008-09-16 2010-03-18 C. R. Bard, Inc. Stent device adhesively bonded to a stent device pusher
US9855158B2 (en) 2008-09-25 2018-01-02 Advanced Bifurcation Systems, Inc. Stent alignment during treatment of a bifurcation
US8979917B2 (en) 2008-09-25 2015-03-17 Advanced Bifurcation Systems, Inc. System and methods for treating a bifurcation
US8828071B2 (en) 2008-09-25 2014-09-09 Advanced Bifurcation Systems, Inc. Methods and systems for ostial stenting of a bifurcation
US9730821B2 (en) 2008-09-25 2017-08-15 Advanced Bifurcation Systems, Inc. Methods and systems for treating a bifurcation with provisional side branch stenting
US9724218B2 (en) 2008-09-25 2017-08-08 Advanced Bifurcation Systems, Inc. Methods and systems for ostial stenting of a bifurcation
US8808347B2 (en) 2008-09-25 2014-08-19 Advanced Bifurcation Systems, Inc. Stent alignment during treatment of a bifurcation
US10219927B2 (en) 2008-09-25 2019-03-05 Advanced Bifurcation Systems Inc. System and methods for treating a bifurcation
US8795347B2 (en) 2008-09-25 2014-08-05 Advanced Bifurcation Systems, Inc. Methods and systems for treating a bifurcation with provisional side branch stenting
US8769796B2 (en) 2008-09-25 2014-07-08 Advanced Bifurcation Systems, Inc. Selective stent crimping
US10219926B2 (en) 2008-09-25 2019-03-05 Advanced Bifurcation Systems Inc. Selective stent crimping
US8821562B2 (en) 2008-09-25 2014-09-02 Advanced Bifurcation Systems, Inc. Partially crimped stent
US9737424B2 (en) 2008-09-25 2017-08-22 Advanced Bifurcation Systems, Inc. Partially crimped stent
US8679172B2 (en) 2009-01-29 2014-03-25 C. R. Bard, Inc. Delivery device for delivering a stent device
US20100204771A1 (en) * 2009-02-11 2010-08-12 Boston Scientific Scimed, Inc. Medical device having a rotatable shaft
US8292940B2 (en) 2009-02-11 2012-10-23 Boston Scientific Scimed, Inc. Medical device having a rotatable shaft
US8945202B2 (en) 2009-04-28 2015-02-03 Endologix, Inc. Fenestrated prosthesis
US9579103B2 (en) 2009-05-01 2017-02-28 Endologix, Inc. Percutaneous method and device to treat dissections
US8920484B2 (en) 2009-05-29 2014-12-30 C. R. Bard, Inc. Transluminal delivery system
US9408607B2 (en) 2009-07-02 2016-08-09 Edwards Lifesciences Cardiaq Llc Surgical implant devices and methods for their manufacture and use
US9757262B2 (en) 2009-07-15 2017-09-12 Endologix, Inc. Stent graft
US8491646B2 (en) 2009-07-15 2013-07-23 Endologix, Inc. Stent graft
US8118856B2 (en) 2009-07-27 2012-02-21 Endologix, Inc. Stent graft
US8821564B2 (en) 2009-07-27 2014-09-02 Endologix, Inc. Stent graft
US9907642B2 (en) 2009-07-27 2018-03-06 Endologix, Inc. Stent graft
US9566178B2 (en) 2010-06-24 2017-02-14 Edwards Lifesciences Cardiaq Llc Actively controllable stent, stent graft, heart valve and method of controlling same
US20110319902A1 (en) * 2010-06-26 2011-12-29 Scott Epstein Catheter delivery system
US9393100B2 (en) 2010-11-17 2016-07-19 Endologix, Inc. Devices and methods to treat vascular dissections
US9254210B2 (en) 2011-02-08 2016-02-09 Advanced Bifurcation Systems, Inc. Multi-stent and multi-balloon apparatus for treating bifurcations and methods of use
US9364356B2 (en) 2011-02-08 2016-06-14 Advanced Bifurcation System, Inc. System and methods for treating a bifurcation with a fully crimped stent
US9549835B2 (en) 2011-03-01 2017-01-24 Endologix, Inc. Catheter system and methods of using same
US20120226341A1 (en) * 2011-03-01 2012-09-06 Endologix, Inc. Catheter system and methods of using same
US9687374B2 (en) 2011-03-01 2017-06-27 Endologix, Inc. Catheter system and methods of using same
US8808350B2 (en) * 2011-03-01 2014-08-19 Endologix, Inc. Catheter system and methods of using same
US9872788B2 (en) 2011-05-05 2018-01-23 Relief Therapies, Inc. Device for protecting hemorrhoids
US9827093B2 (en) 2011-10-21 2017-11-28 Edwards Lifesciences Cardiaq Llc Actively controllable stent, stent graft, heart valve and method of controlling same
US10130798B2 (en) 2013-07-15 2018-11-20 John P. Pigott Balloon catheter having a retractable sheath and locking mechanism
WO2016115252A1 (en) * 2015-01-13 2016-07-21 Pigott John P Balloon catheter having a retractable sheath and locking mechanism
US10245166B2 (en) 2017-05-31 2019-04-02 Endologix, Inc. Apparatus and method of placement of a graft or graft system

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EP0758871A1 (en) 1997-02-26
AT272989T (en) 2004-08-15
PT758871E (en) 2004-10-29
DE69533356T2 (en) 2004-12-30
WO1995031155A1 (en) 1995-11-23
US5569296A (en) 1996-10-29
ES2224127T3 (en) 2005-03-01
EP0758871B1 (en) 2004-08-11
US5456694A (en) 1995-10-10
AU2597195A (en) 1995-12-05
DE69533356D1 (en) 2004-09-16
JPH10500335A (en) 1998-01-13
JP3716862B2 (en) 2005-11-16
DK758871T3 (en)
DK0758871T3 (en) 2004-09-06
CA2189794A1 (en) 1995-11-23

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