US462990A - William oppenheimek - Google Patents
William oppenheimek Download PDFInfo
- Publication number
- US462990A US462990A US462990DA US462990A US 462990 A US462990 A US 462990A US 462990D A US462990D A US 462990DA US 462990 A US462990 A US 462990A
- Authority
- US
- United States
- Prior art keywords
- william
- oppenheimek
- soluble
- casing
- partition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000003814 drug Substances 0.000 description 16
- 239000002775 capsule Substances 0.000 description 12
- 238000005192 partition Methods 0.000 description 12
- 229940079593 drugs Drugs 0.000 description 8
- 238000004519 manufacturing process Methods 0.000 description 4
- 238000002360 preparation method Methods 0.000 description 4
- 235000014647 Lens culinaris subsp culinaris Nutrition 0.000 description 2
- 244000043158 Lens esculenta Species 0.000 description 2
- 210000002784 Stomach Anatomy 0.000 description 2
- 150000001875 compounds Chemical class 0.000 description 2
- 239000012530 fluid Substances 0.000 description 2
- 239000008187 granular material Substances 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 239000006187 pill Substances 0.000 description 2
- 239000000843 powder Substances 0.000 description 2
- 239000007787 solid Substances 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 239000003643 water by type Substances 0.000 description 2
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
Definitions
- GAPSULE i No. 462,990. Patented Nov. 10, 18911..
- VILLIAM OPPENI-IEIMER, OF LONDON, ENGLAND- CAPSULE VILLIAM OPPENI-IEIMER, OF LONDON, ENGLAND- CAPSULE.
- My invention relates' to those forms of medicine which are conveyed into the system intact and are only intended todissolve and intermix after being taken into the stomach or elsewhere, where they are intended to operate; and the object of my i11- vention is to improve and extend the use of such preparations by manufacturing them in the form of capsules, each having a partition dividing it into a series of chambers which contain ⁇ the-different kinds of Inedieine.
- FIG. 1 is a transverse sectional view 0f a capsuleeinbodying my invention.
- Figs. 2 to 20, inclusive, are similar views showing variations in the shape of the capsule.
- the capsules are each composed of a soluble casing or shell, Which is integral with a soluble partition or partitions 3, formed of the saine material as the shell or casing, for the purpose of dividing the soluble casing into a series of chambers 2, adapted to oontain different kinds of medicine.
- the Inedicines are preserved entirely separate from each other by the soluble partition or partitions 3, formed integral with the soluble easing, as before explained, and the casing and partition or partit-ions dissolve When taken internally for the purpose of liberating the medicines.
- the inelosed medicine may be in the form of poWder,uid,or solid, as found best suited to the required treatment.
- I claim- A capsuleconsisting; ⁇ of a soluble shell or casing formed integral with a soluble partition to provide separated chambers for different kinds of medicine, said shell or casing and partition dissolving when taken internally for the purpose of liberating the medicines, substantially as described.
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Description
(No Model.)
W. OPPENHEIMER.
GAPSULE. i No. 462,990. Patented Nov. 10, 18911..
fy/ @2 193.- @f4 j l j j i@ @f @1% Y 3 l j s @d je'g Jyf z '1 .e j o., f o
I? .9, Ij, I" jj. 'j
yi 71 W j@ za'ge jfzyj 1 j j j UNITED STATES PATENT OFFICE.
VILLIAM OPPENI-IEIMER, OF LONDON, ENGLAND- CAPSULE.
SPECIFICATION forming part'of Letters Patent No. 462,990, dated November 10, 1891..
Application filed September 23, 1891l Serial No. 398,711. (No specimens.) Patented in England January 29, 1891, No.1,651.
To L ZZ whom it may concern.-
Be it known that I, WILLIAM OPPENIIEIMEE, manufacturing chemist, a subject of the Queen of Great Britain, residing at 1 and 3 Sun Street and 39 XVilsonStreet, Finsbury Square, London, England, have invented a certain new and useful Improvement in Capsules and in the preparation of the same for use, (for which I have applied for a patent in Great Britain, No. 1,651, bearing,` date January 29, 1891,) of which the followingr is a specification.
My invention relates' to those forms of medicine which are conveyed into the system intact and are only intended todissolve and intermix after being taken into the stomach or elsewhere, where they are intended to operate; and the object of my i11- vention is to improve and extend the use of such preparations by manufacturing them in the form of capsules, each having a partition dividing it into a series of chambers which contain `the-different kinds of Inedieine.
The invention is illustrated by the accompanying drawings, in Which- Figure 1 is a transverse sectional view 0f a capsuleeinbodying my invention. Figs. 2 to 20, inclusive, are similar views showing variations in the shape of the capsule.
In carrying` out my invention I make up the compound medicines as capsules, Waters,
pills, or granules 1, of any convenient form,
such as the lentil or double-convex lens or globular, semi-globular, double globular, or of any other preferred shape.
The capsules are each composed of a soluble casing or shell, Which is integral with a soluble partition or partitions 3, formed of the saine material as the shell or casing, for the purpose of dividing the soluble casing into a series of chambers 2, adapted to oontain different kinds of medicine. The Inedicines are preserved entirely separate from each other by the soluble partition or partitions 3, formed integral with the soluble easing, as before explained, and the casing and partition or partit-ions dissolve When taken internally for the purpose of liberating the medicines. The inelosed medicine may be in the form of poWder,uid,or solid, as found best suited to the required treatment.
The medicines so prepared as herein described Inay, if preferred, be dissolved or mixed in water or other suitable fluid or matter and taken as a draft.
I claim- A capsuleconsisting;` of a soluble shell or casing formed integral with a soluble partition to provide separated chambers for different kinds of medicine, said shell or casing and partition dissolving when taken internally for the purpose of liberating the medicines, substantially as described.
Dated this 16th day of June, 189l.
WILLIAM OPPENHEIMIER.
Witnesses:
GEORGE F. DOWNING, SQual'z'ty Oom, London, W. O.
JOSEPH LAKE, 17 Gracechurch Street, London, E. C.
Publications (1)
Publication Number | Publication Date |
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US462990A true US462990A (en) | 1891-11-10 |
Family
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Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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US462990D Expired - Lifetime US462990A (en) | William oppenheimek |
Country Status (1)
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US (1) | US462990A (en) |
Cited By (34)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2452273A (en) * | 1945-08-20 | 1948-10-26 | Robert H Van Sant | Applicator |
US2473368A (en) * | 1944-02-25 | 1949-06-14 | Flintermann Gerhard | Suppository |
US2497212A (en) * | 1945-10-31 | 1950-02-14 | Alfonso M Donofrio | Method of manufacturing capsules |
US2768115A (en) * | 1951-11-02 | 1956-10-23 | Bristol Lab Inc | Penicillin-aspirin tablets |
US3046605A (en) * | 1960-01-12 | 1962-07-31 | American Cyanamid Co | Manufacture of two-color and two-tone soft shell capsules |
US3087606A (en) * | 1953-10-19 | 1963-04-30 | Minnesota Mining & Mfg | Package of inter-reactive materials |
US3345265A (en) * | 1963-10-09 | 1967-10-03 | Kendall & Co | Multiple layer tablet with calcium salt central core separated from soluble fluoride outer coating |
US3844285A (en) * | 1969-08-28 | 1974-10-29 | Commw Scient Ind Res Org | Device for administration to ruminants |
US3922338A (en) * | 1973-07-12 | 1975-11-25 | Choay Sa | Tablets containing in their mass controlled-release micro-capsules and process for manufacture of said tablets |
US4139589A (en) * | 1975-02-26 | 1979-02-13 | Monique Beringer | Process for the manufacture of a multi-zone tablet and tablet manufactured by this process |
US4198390A (en) * | 1979-01-31 | 1980-04-15 | Rider Joseph A | Simethicone antacid tablet |
US4260596A (en) * | 1979-08-13 | 1981-04-07 | Bristol-Myers Company | Edible unit dosage form consisting of outer mannitol shell and inner liquid or gel center and method for manufacturing the same |
US4563358A (en) * | 1979-01-29 | 1986-01-07 | F. B. Mercer Limited | Composite food product and method for making the same |
WO1987006128A1 (en) * | 1986-04-07 | 1987-10-22 | Clemetson Ab Charles | Catechin coated ascorbic acid and method |
US4793493A (en) * | 1986-09-18 | 1988-12-27 | Makiej Jr Walter J | Multidose capsules |
US4850489A (en) * | 1986-07-11 | 1989-07-25 | Hoechst Aktiengesellschaft | Dispensing packs containing pharmaceutical combinations for sequential administration |
US5074426A (en) * | 1986-11-13 | 1991-12-24 | Warner-Lambert Company | Dividable capsule |
US5314696A (en) * | 1991-06-27 | 1994-05-24 | Paulos Manley A | Methods for making and administering a blinded oral dosage form and blinded oral dosage form therefor |
US5824338A (en) * | 1996-08-19 | 1998-10-20 | L. Perrigo Company | Caplet and gelatin covering therefor |
WO1999025629A1 (en) * | 1997-11-17 | 1999-05-27 | Merck & Co., Inc. | Multicompartment container for combination products |
US6428770B1 (en) * | 1997-12-03 | 2002-08-06 | Kao Corporation | Solid preparation for oral hygiene |
WO2010096558A1 (en) | 2009-02-18 | 2010-08-26 | Eyeon Particle Sciences Llc | Bi-functional co-polymer use for ophthalmic and other topical and local applications |
US20110003655A1 (en) * | 2009-07-01 | 2011-01-06 | Chernick Mark J | Segmented High-Bounce Toy Water Ball |
CN102151410A (en) * | 2010-02-11 | 2011-08-17 | 马克·J·切尔尼克 | Toy ball |
US8920856B2 (en) | 2009-10-08 | 2014-12-30 | Intercontinental Great Brands Llc | Co-extruded layered candy and gum apparatus and methods |
US9060526B2 (en) | 2009-01-22 | 2015-06-23 | Intercontinental Great Brands Llc | Confectionery processing |
US20150258287A1 (en) * | 2013-08-22 | 2015-09-17 | Sipnose Ltd | Device to deliver a predetermined amount of a substance to a natural orifice of the body |
USD766014S1 (en) * | 2014-03-21 | 2016-09-13 | Jin-Young Choi | Pillow for baby |
US20180200685A1 (en) * | 2017-01-11 | 2018-07-19 | Roy C. Putrino | Mixing device and methods thereof |
USD864151S1 (en) * | 2017-10-20 | 2019-10-22 | Shenzhen Fogaap Technologies Co., Ltd. | Earphones |
US11116914B2 (en) | 2014-11-09 | 2021-09-14 | Sipnose Ltd. | Device and method for aerosolized delivering of substance to a natural orifice of the body |
US11278682B2 (en) | 2014-11-09 | 2022-03-22 | Sipnose Ltd. | Device and method for aerosolized delivery of substance to a natural orifice of the body |
US11471618B2 (en) | 2014-11-09 | 2022-10-18 | Sipnose Ltd. | Adjustable dosing delivery and multi sectioned drug compartment |
US11992604B2 (en) | 2014-11-09 | 2024-05-28 | Sipnose Ltd. | Devices and methods for delivering a substance to a body cavity |
-
0
- US US462990D patent/US462990A/en not_active Expired - Lifetime
Cited By (39)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2473368A (en) * | 1944-02-25 | 1949-06-14 | Flintermann Gerhard | Suppository |
US2452273A (en) * | 1945-08-20 | 1948-10-26 | Robert H Van Sant | Applicator |
US2497212A (en) * | 1945-10-31 | 1950-02-14 | Alfonso M Donofrio | Method of manufacturing capsules |
US2768115A (en) * | 1951-11-02 | 1956-10-23 | Bristol Lab Inc | Penicillin-aspirin tablets |
US3087606A (en) * | 1953-10-19 | 1963-04-30 | Minnesota Mining & Mfg | Package of inter-reactive materials |
US3046605A (en) * | 1960-01-12 | 1962-07-31 | American Cyanamid Co | Manufacture of two-color and two-tone soft shell capsules |
US3345265A (en) * | 1963-10-09 | 1967-10-03 | Kendall & Co | Multiple layer tablet with calcium salt central core separated from soluble fluoride outer coating |
US3844285A (en) * | 1969-08-28 | 1974-10-29 | Commw Scient Ind Res Org | Device for administration to ruminants |
US3922338A (en) * | 1973-07-12 | 1975-11-25 | Choay Sa | Tablets containing in their mass controlled-release micro-capsules and process for manufacture of said tablets |
US4139589A (en) * | 1975-02-26 | 1979-02-13 | Monique Beringer | Process for the manufacture of a multi-zone tablet and tablet manufactured by this process |
US4563358A (en) * | 1979-01-29 | 1986-01-07 | F. B. Mercer Limited | Composite food product and method for making the same |
US4198390A (en) * | 1979-01-31 | 1980-04-15 | Rider Joseph A | Simethicone antacid tablet |
US4260596A (en) * | 1979-08-13 | 1981-04-07 | Bristol-Myers Company | Edible unit dosage form consisting of outer mannitol shell and inner liquid or gel center and method for manufacturing the same |
WO1987006128A1 (en) * | 1986-04-07 | 1987-10-22 | Clemetson Ab Charles | Catechin coated ascorbic acid and method |
US4850489A (en) * | 1986-07-11 | 1989-07-25 | Hoechst Aktiengesellschaft | Dispensing packs containing pharmaceutical combinations for sequential administration |
US4793493A (en) * | 1986-09-18 | 1988-12-27 | Makiej Jr Walter J | Multidose capsules |
US5074426A (en) * | 1986-11-13 | 1991-12-24 | Warner-Lambert Company | Dividable capsule |
US5558878A (en) * | 1991-06-27 | 1996-09-24 | Captab, L.L.C. | Method for blinding a tableted medication |
US5576019A (en) * | 1991-06-27 | 1996-11-19 | Captab 11C | Method for blinding a medication |
US5314696A (en) * | 1991-06-27 | 1994-05-24 | Paulos Manley A | Methods for making and administering a blinded oral dosage form and blinded oral dosage form therefor |
US5824338A (en) * | 1996-08-19 | 1998-10-20 | L. Perrigo Company | Caplet and gelatin covering therefor |
WO1999025629A1 (en) * | 1997-11-17 | 1999-05-27 | Merck & Co., Inc. | Multicompartment container for combination products |
US6428770B1 (en) * | 1997-12-03 | 2002-08-06 | Kao Corporation | Solid preparation for oral hygiene |
US9060526B2 (en) | 2009-01-22 | 2015-06-23 | Intercontinental Great Brands Llc | Confectionery processing |
EP3246048A1 (en) | 2009-02-18 | 2017-11-22 | Eyeon Particle Sciences LLC | Bi-functional co-polymer use for ophthalmic and other topical and local applications |
WO2010096558A1 (en) | 2009-02-18 | 2010-08-26 | Eyeon Particle Sciences Llc | Bi-functional co-polymer use for ophthalmic and other topical and local applications |
US20110003655A1 (en) * | 2009-07-01 | 2011-01-06 | Chernick Mark J | Segmented High-Bounce Toy Water Ball |
US8920856B2 (en) | 2009-10-08 | 2014-12-30 | Intercontinental Great Brands Llc | Co-extruded layered candy and gum apparatus and methods |
CN102151410A (en) * | 2010-02-11 | 2011-08-17 | 马克·J·切尔尼克 | Toy ball |
US20150258287A1 (en) * | 2013-08-22 | 2015-09-17 | Sipnose Ltd | Device to deliver a predetermined amount of a substance to a natural orifice of the body |
US11383048B2 (en) * | 2013-08-22 | 2022-07-12 | Sipnose Ltd. | Device to deliver a predetermined amount of a substance to a natural orifice of the body |
USD766014S1 (en) * | 2014-03-21 | 2016-09-13 | Jin-Young Choi | Pillow for baby |
US11116914B2 (en) | 2014-11-09 | 2021-09-14 | Sipnose Ltd. | Device and method for aerosolized delivering of substance to a natural orifice of the body |
US11278682B2 (en) | 2014-11-09 | 2022-03-22 | Sipnose Ltd. | Device and method for aerosolized delivery of substance to a natural orifice of the body |
US11471618B2 (en) | 2014-11-09 | 2022-10-18 | Sipnose Ltd. | Adjustable dosing delivery and multi sectioned drug compartment |
US11992604B2 (en) | 2014-11-09 | 2024-05-28 | Sipnose Ltd. | Devices and methods for delivering a substance to a body cavity |
US20180200685A1 (en) * | 2017-01-11 | 2018-07-19 | Roy C. Putrino | Mixing device and methods thereof |
US10835881B2 (en) * | 2017-01-11 | 2020-11-17 | Roy C. Putrino | Mixing device and methods thereof |
USD864151S1 (en) * | 2017-10-20 | 2019-10-22 | Shenzhen Fogaap Technologies Co., Ltd. | Earphones |
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