US3830569A - Process and apparatus for counting biological particles - Google Patents

Process and apparatus for counting biological particles Download PDF

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Publication number
US3830569A
US3830569A US00386280A US38628073A US3830569A US 3830569 A US3830569 A US 3830569A US 00386280 A US00386280 A US 00386280A US 38628073 A US38628073 A US 38628073A US 3830569 A US3830569 A US 3830569A
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United States
Prior art keywords
cells
blood
red
accordance
hematocrit
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Expired - Lifetime
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US00386280A
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English (en)
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J Meric
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    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06MCOUNTING MECHANISMS; COUNTING OF OBJECTS NOT OTHERWISE PROVIDED FOR
    • G06M11/00Counting of objects distributed at random, e.g. on a surface
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
    • G01N15/02Investigating particle size or size distribution
    • G01N15/0205Investigating particle size or size distribution by optical means, e.g. by light scattering, diffraction, holography or imaging
    • G01N15/0211Investigating a scatter or diffraction pattern
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47Scattering, i.e. diffuse reflection
    • G01N2021/4704Angular selective
    • G01N2021/4711Multiangle measurement
    • G01N2021/4716Using a ring of sensors, or a combination of diaphragm and sensors; Annular sensor

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  • Chemical & Material Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Theoretical Computer Science (AREA)
  • Dispersion Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
US00386280A 1972-08-10 1973-08-07 Process and apparatus for counting biological particles Expired - Lifetime US3830569A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7228858A FR2195907A5 (ko) 1972-08-10 1972-08-10

Publications (1)

Publication Number Publication Date
US3830569A true US3830569A (en) 1974-08-20

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ID=9103117

Family Applications (1)

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US00386280A Expired - Lifetime US3830569A (en) 1972-08-10 1973-08-07 Process and apparatus for counting biological particles

Country Status (9)

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US (1) US3830569A (ko)
JP (1) JPS49125097A (ko)
BE (1) BE803075A (ko)
DE (1) DE2340252A1 (ko)
ES (1) ES417763A1 (ko)
FR (1) FR2195907A5 (ko)
GB (1) GB1400640A (ko)
IT (1) IT1008026B (ko)
NL (1) NL7310960A (ko)

Cited By (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3923397A (en) * 1974-05-29 1975-12-02 Dolive Stephen E Hematocrit measuring method
US3930726A (en) * 1974-05-29 1976-01-06 Reginald C. Shuck System for measuring volumetric ratios of liquid suspended solids
US3990851A (en) * 1974-02-27 1976-11-09 Behringwerke Aktiengesellschaft Process and device for measuring antigen-antibody reactions
US4052600A (en) * 1975-01-06 1977-10-04 Leeds & Northrup Company Measurement of statistical parameters of a distribution of suspended particles
US4139303A (en) * 1977-01-21 1979-02-13 The Board Of Regents Of The University Of Washington Adaptive coherent optical processing method and apparatus for recognizing and counting objects
JPS5537998A (en) * 1978-09-06 1980-03-17 Ortho Diagnostics Method of and apparatus for detecting blood plasma plate in all blood
US4303336A (en) * 1978-08-28 1981-12-01 Baxter Travenol Laboratories, Inc. Method and apparatus for making a rapid measurement of the hematocrit of blood
US4441816A (en) * 1982-03-25 1984-04-10 The United States Of America As Represented By The United States Department Of Energy Optical double-slit particle measuring system
US4522494A (en) * 1982-07-07 1985-06-11 The United States Of America As Represented By The Department Of Health And Human Services Non-invasive optical assessment of platelet viability
EP0207176A1 (de) * 1985-06-07 1987-01-07 Fritsch GmbH Gerät zur Bestimmung von Korngrössen
WO1988007198A1 (en) * 1987-03-13 1988-09-22 Coulter Electronics, Inc. Multi-part differential analyzing apparatus utilizing light scatter techniques
EP0575712A2 (en) * 1992-03-31 1993-12-29 University Of Manitoba Spectrophotometric blood analysis
US5601080A (en) * 1994-12-28 1997-02-11 Coretech Medical Technologies Corporation Spectrophotometric blood analysis
EP0696731A3 (en) * 1994-08-08 1997-10-15 Toa Medical Electronics Cytoanalyzer
US5844685A (en) * 1996-07-30 1998-12-01 Bayer Corporation Reference laser beam sampling apparatus
US5872627A (en) * 1996-07-30 1999-02-16 Bayer Corporation Method and apparatus for detecting scattered light in an analytical instrument
US5936729A (en) * 1996-03-26 1999-08-10 Horiba, Ltd. Photo detector assembly for measuring particle sizes
US6041246A (en) * 1997-10-14 2000-03-21 Transonic Systems, Inc. Single light sensor optical probe for monitoring blood parameters and cardiovascular measurements
US20030130570A1 (en) * 1997-10-14 2003-07-10 Transonic Systems, Inc. Sensor calibration and blood volume determination
US20050255600A1 (en) * 2004-05-14 2005-11-17 Honeywell International Inc. Portable sample analyzer cartridge
US20110222050A1 (en) * 2010-03-10 2011-09-15 Sony Corporation Optical measuring device and optical measuring method
CN103487362A (zh) * 2013-10-16 2014-01-01 中国工程物理研究院激光聚变研究中心 一种激光粒子测量探头
US9280726B2 (en) 2009-12-18 2016-03-08 Fpinnovation On-line macrocontaminant analyser and method
CN107941662A (zh) * 2017-11-10 2018-04-20 吉林大学 一种利用强场激光检测火焰内颗粒物分布的装置与方法
US10473519B2 (en) * 2013-03-15 2019-11-12 Beckman Coulter, Inc. Radiated light filtering for a flow cytometer
US20220412866A1 (en) * 2019-11-22 2022-12-29 Ams Ag Optical particle counter for air quality assessment

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2445523A1 (fr) * 1978-12-28 1980-07-25 Sable Sarl Procede pour mesurer le volume des matieres en suspension dans un liquide
EP0013247B1 (fr) * 1978-12-28 1983-02-09 Omnium D'assainissement Procédé pour mesurer le volume de matières en suspension dans un liquide avec application, notamment, à la détermination automatique de la qualité d'une eau
US4274741A (en) * 1979-09-26 1981-06-23 Compagnie Industrielle Des Lasers Device for determining the granulometric composition of a mixture of particles by diffraction of light
US4412004A (en) * 1981-06-26 1983-10-25 Technicon Instruments Corporation Method for treating red blood cells to effect sphering and reagent therefor
FR2521294A1 (fr) * 1982-02-05 1983-08-12 Bajard Jean Procede de granulometrie interferentielle globale applicable notamment a des particules biologiques polydispersees
JPS63215942A (ja) * 1987-03-04 1988-09-08 Natl Aerospace Lab 粒子径分布計測用光電変換センサ−

Cited By (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3990851A (en) * 1974-02-27 1976-11-09 Behringwerke Aktiengesellschaft Process and device for measuring antigen-antibody reactions
US3930726A (en) * 1974-05-29 1976-01-06 Reginald C. Shuck System for measuring volumetric ratios of liquid suspended solids
US3923397A (en) * 1974-05-29 1975-12-02 Dolive Stephen E Hematocrit measuring method
US4052600A (en) * 1975-01-06 1977-10-04 Leeds & Northrup Company Measurement of statistical parameters of a distribution of suspended particles
US4139303A (en) * 1977-01-21 1979-02-13 The Board Of Regents Of The University Of Washington Adaptive coherent optical processing method and apparatus for recognizing and counting objects
US4303336A (en) * 1978-08-28 1981-12-01 Baxter Travenol Laboratories, Inc. Method and apparatus for making a rapid measurement of the hematocrit of blood
JPS6351268B2 (ko) * 1978-09-06 1988-10-13 Ooso Daiagunosuteitsuku Shisutemuzu Inc
JPS5537998A (en) * 1978-09-06 1980-03-17 Ortho Diagnostics Method of and apparatus for detecting blood plasma plate in all blood
US4441816A (en) * 1982-03-25 1984-04-10 The United States Of America As Represented By The United States Department Of Energy Optical double-slit particle measuring system
US4522494A (en) * 1982-07-07 1985-06-11 The United States Of America As Represented By The Department Of Health And Human Services Non-invasive optical assessment of platelet viability
US4755052A (en) * 1985-06-07 1988-07-05 Fritsch Gmbh Apparatus for determining grain size
EP0207176A1 (de) * 1985-06-07 1987-01-07 Fritsch GmbH Gerät zur Bestimmung von Korngrössen
WO1988007198A1 (en) * 1987-03-13 1988-09-22 Coulter Electronics, Inc. Multi-part differential analyzing apparatus utilizing light scatter techniques
AU632393B2 (en) * 1987-03-13 1992-12-24 Coulter International Corporation Multi-part differential analyzing apparatus utilizing light scatter techniques
EP0575712A2 (en) * 1992-03-31 1993-12-29 University Of Manitoba Spectrophotometric blood analysis
EP0575712A3 (en) * 1992-03-31 1994-06-08 Univ Manitoba Spectrophotometric blood analysis
US5331958A (en) * 1992-03-31 1994-07-26 University Of Manitoba Spectrophotometric blood analysis
EP0696731A3 (en) * 1994-08-08 1997-10-15 Toa Medical Electronics Cytoanalyzer
US5737078A (en) * 1994-08-08 1998-04-07 Toa Medical Electronics Co., Ltd. Cytoanalyzer using separate sensing portions on a dectector and method for aligning the same
US5601080A (en) * 1994-12-28 1997-02-11 Coretech Medical Technologies Corporation Spectrophotometric blood analysis
US5936729A (en) * 1996-03-26 1999-08-10 Horiba, Ltd. Photo detector assembly for measuring particle sizes
US5844685A (en) * 1996-07-30 1998-12-01 Bayer Corporation Reference laser beam sampling apparatus
US5872627A (en) * 1996-07-30 1999-02-16 Bayer Corporation Method and apparatus for detecting scattered light in an analytical instrument
US7734322B2 (en) 1997-10-14 2010-06-08 Transonic Systems, Inc. Blood volume determination and sensor calibration
US6041246A (en) * 1997-10-14 2000-03-21 Transonic Systems, Inc. Single light sensor optical probe for monitoring blood parameters and cardiovascular measurements
US6493567B1 (en) 1997-10-14 2002-12-10 Transonic Systems, Inc. Single light sensor optical probe for monitoring blood parameters and cardiovascular measurements
US20030130570A1 (en) * 1997-10-14 2003-07-10 Transonic Systems, Inc. Sensor calibration and blood volume determination
US6718190B2 (en) 1997-10-14 2004-04-06 Transonic Systems, Inc. Sensor calibration and blood volume determination
US8071051B2 (en) * 2004-05-14 2011-12-06 Honeywell International Inc. Portable sample analyzer cartridge
US20050255600A1 (en) * 2004-05-14 2005-11-17 Honeywell International Inc. Portable sample analyzer cartridge
US8540946B2 (en) 2004-05-14 2013-09-24 Honeywell International Inc. Portable sample analyzer cartridge
US9280726B2 (en) 2009-12-18 2016-03-08 Fpinnovation On-line macrocontaminant analyser and method
US20110222050A1 (en) * 2010-03-10 2011-09-15 Sony Corporation Optical measuring device and optical measuring method
US8780338B2 (en) * 2010-03-10 2014-07-15 Sony Corporation Optical measuring device and optical measuring method
US9766174B2 (en) 2010-03-10 2017-09-19 Sony Corporation Optical measuring device and optical measuring method
US10473519B2 (en) * 2013-03-15 2019-11-12 Beckman Coulter, Inc. Radiated light filtering for a flow cytometer
CN103487362A (zh) * 2013-10-16 2014-01-01 中国工程物理研究院激光聚变研究中心 一种激光粒子测量探头
CN103487362B (zh) * 2013-10-16 2015-09-23 中国工程物理研究院激光聚变研究中心 一种激光粒子测量探头
CN107941662A (zh) * 2017-11-10 2018-04-20 吉林大学 一种利用强场激光检测火焰内颗粒物分布的装置与方法
US20220412866A1 (en) * 2019-11-22 2022-12-29 Ams Ag Optical particle counter for air quality assessment

Also Published As

Publication number Publication date
DE2340252A1 (de) 1974-02-21
GB1400640A (en) 1975-07-16
IT1008026B (it) 1976-11-10
NL7310960A (ko) 1974-02-12
FR2195907A5 (ko) 1974-03-08
BE803075A (fr) 1973-11-16
ES417763A1 (es) 1976-02-16
JPS49125097A (ko) 1974-11-29

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