US3746000A - Continuous feed medical nebulizer - Google Patents

Continuous feed medical nebulizer Download PDF

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Publication number
US3746000A
US3746000A US00214796A US3746000DA US3746000A US 3746000 A US3746000 A US 3746000A US 00214796 A US00214796 A US 00214796A US 3746000D A US3746000D A US 3746000DA US 3746000 A US3746000 A US 3746000A
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US
United States
Prior art keywords
liquid
lumen
air
drain
supply source
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
US00214796A
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English (en)
Inventor
F Edwards
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
American Hospital Supply Corp
Baxter International Inc
Original Assignee
American Hospital Supply Corp
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Filing date
Publication date
Application filed by American Hospital Supply Corp filed Critical American Hospital Supply Corp
Application granted granted Critical
Publication of US3746000A publication Critical patent/US3746000A/en
Assigned to BAXTER TRAVENOL LABORATORIES, INC. A CORP. OF DE reassignment BAXTER TRAVENOL LABORATORIES, INC. A CORP. OF DE MERGER (SEE DOCUMENT FOR DETAILS). EFFECTIVE ON 11/25/1985 ILLINOIS Assignors: AMERICAN HOSPITAL SUPPLY CORPORATION INTO
Assigned to BAXTER INTERNATIONAL INC. reassignment BAXTER INTERNATIONAL INC. CHANGE OF NAME (SEE DOCUMENT FOR DETAILS). Assignors: BAXTER TRAVENOL LABORATOIRES, INC., A CORP. OF DE
Assigned to BAXTER INTERNATIONAL INC. reassignment BAXTER INTERNATIONAL INC. CHANGE OF NAME (SEE DOCUMENT FOR DETAILS). EFFECTIVE ON 10/17/1988 Assignors: BAXTER TRAVENOL LABORATORIES, INC., A CORP. OF DE
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0085Inhalators using ultrasonics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/10Preparation of respiratory gases or vapours
    • A61M16/14Preparation of respiratory gases or vapours by mixing different fluids, one of them being in a liquid phase
    • A61M16/16Devices to humidify the respiration air
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B05SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05BSPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B17/00Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups
    • B05B17/04Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods
    • B05B17/06Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations
    • B05B17/0607Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations generated by electrical means, e.g. piezoelectric transducers
    • B05B17/0615Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations generated by electrical means, e.g. piezoelectric transducers spray being produced at the free surface of the liquid or other fluent material in a container and subjected to the vibrations
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S261/00Gas and liquid contact apparatus
    • Y10S261/65Vaporizers

Definitions

  • ABSTRACT A continuous fecd nebulizcr system for medical inhalation therapy in which a rigiddual lumen feed tube is connected with a liquid supply source and extends into a nebulizing chamber.
  • This feed tube continuously replenishes liquid as it is nebulized and has a liquid drain lumen that is of a smaller cross sectional area and extends below an air return lumen.
  • Constricted orifice structures adjacent a bottom of the liquid drain lumen and a top of the air return lumen damp out sudden changes of liquid level in the chamber as this level ranges between a bottom of the liquid drain lumen and a bottom of the air return lumen. This structure causes more uniform nebulization within the continuous feed nebulizer.
  • An ultrasonic nebulizer applies a tuned ultrasonic energy source to a medical liquid and causes this liquid to form a geyser at its surface.
  • the geyser is comprised of microscopic liquid particles that are readily inhaled by the patient and absorbed through his respiratory system.
  • the liquid drain tube and the air return tube work like this.
  • the nebulizing chamber dropped below the lower end of the liquid drain tube more liquid would flow into the chamber from the liquid supply bottle. Air in the liquid supply bottle was replaced with air moving up the air return tube. When the level reached the bottom of the air return tube it would cut off the air flow back to the bottle and a vacuum lock would occur and prvent additional liquid drainage.
  • One of the mainproblems with these continuous feed nebulizer devices was that their level surged up and down between its lowerends of the liquid and air tubes. This surging can cause changes in nebulizing rates and generally affect the geyser erupting from the surface of the liquid.
  • These continuous feed nebulizer systems are used over very prolonged periods of time, on very ill patients, and this surging causes serious problems in accurately controlling the nebulization of medicament being continually breathed in by the patient.
  • the air return passage has a restricted orifice adjacent its top end and the liquid drain lumen has a restricted orifice adjacent its bottom end. These two restricted orifices tend to break up the air flowing back into the liquid supply bottle and also slowly dispenses liquid from the liquid drain tube.
  • the combination of the large diameter tubes and the restricted orifices cause smooth changes in the liquid level within the nebulizing chamber and give much better control of nebulization within the nebulizing chamber.
  • FIG. 1 is a front elevational view partially in section showing the liquid supply source, the nebulizing chamber and the dual lumen feed tube;
  • FIG. 2 is an enlarged section taken along line 2-2 of FIG. 1;
  • FIG. 3 is a sectional view taken along line 33 of FIG. 1 showing the oval configuration of the feed tube and how it fits against a side of the nebulizer collecting cup;
  • FIG. 4 is an enlarged sectional view of the dual lumen feed tube showing its two constricted orifices
  • FIG. 5 is a top view taken along line 5-5 of FIG. 4;
  • FIG. 6 is a bottom view taken along line 66 of FIG. 4.
  • FIG. 1 shows a liquid supply source 1 in the form of a liquid filled bottle with an outlet closure system 2. Connected to this outlet are two flexible hollow lead tubes 3 and 4. As shown in FIG. 1, liquid drains down tube 3 and air bubbles flow up into liquid supply source 1 through flexible tube 4.
  • a hollow thermoplastic nebulizing chamber 5 Spaced below the liquid supply source 1 is a hollow thermoplastic nebulizing chamber 5.
  • This nebulizing chamber has an inlet tube 6 and an outlet tube 7 which connect to the apparatus to feed the nebulized liquid to the patient.
  • this apparatus includes a blower system that forces air in through tube 6 into chamber 5 where it picks up nebulized liquid particles in the chamber and thereafter forces them out through tube 7 and to the patient for breathing.
  • Nlebulizationof a liquid 8 at a lower portion of the chamber causes a geyser (not shown) to erupt from the surface of the liquid 8 and be picked up by the air stream being fed to the patient.
  • feed tube 12 has two tubular connectors 13 and 14 at its upper end which telescopically fit into the two hollow flexible lead lines 3 and 4 from liquid supply source 1.
  • the feed tube 12 also has an integrally formed cap member that includes a lateral top wall 15 and a depending skirt 16 that engages with and fits over an upstanding inlet port system 17 of the nebulizer container.
  • the rigid feed tube forms a connecting link between the tubes 3 and 4 and the liquid 8 inthe nebulizing chamber.
  • a liquid drain lumen 18 extends a given distance below the air return lumen 19. This extension of the liquid drain lumen controls the range of vertical movement of the upper surface 20 of liquid 8.
  • the nebulizing chamber will begin to fill. This occurs because air will flow up the air return pass lumen 19 to replace air in liquid supply source 1 so liquid can drain.
  • level 20 of liquid 8 reaches the end of end 22 of the air return lumen the liquid will block off air passage therethrough. This causes a vacuum lock in the liquid supply source and liquid 18 will cease to flow.
  • surface 20 will drop and again let air flow back into bottle 1. This continuous process causes a continuous feed of liquid to the nebulizing chamber and provides a generally constant liquid level that can be efficiently nebulized.
  • this surging is substantially reduced by including a retricted orifice 23 at a top portion of the air return lumen 19.
  • This causes air to be funneled in by the large lumen 19 with little resistance to flow and then slowly metered out through orifice 23.
  • this orifice is between 0.040 and 0.100 inches in diameter. I have found this size of orifice tends to break up large slugs of air coming up air lumen 19.
  • the air dispensed into liquid source 1 is in very fine metered bubbles which slowly release the vacuum lock in the liquid supply bottle 1. This causes the liquid to drain down liquid drain lumen 18 more slowly.
  • the lower end of the air tube 19 is beveled to reduce the surface area of contact between the liquid surface and air tube at the critical opening and closing of the air passage. This improves the smoothness of the opening and closing of the air passage's lower port.
  • the beveled lower end of the air tube is preferred but it could be made horizontal if desired.
  • the liquid drain passage 18 and the air return lumen 19 have cross sectional areas substantially larger 6 cross sectional area more than 3 times the size of liquid drain lumen 18. This allows large slugs of air to collect in lumen 19 before they are metered through fixed orifice 23.
  • the diameter oflumen 18 is between 0. l 25 and 0.150 inch.
  • Lumen 19 is of irregular cross sectional area but includes a cross section more than three times the cross sectional area of liquid drain lumen 18 as shown in FIGS. 2 and 3.
  • the oval configuration of the feed tube fits against a side wall of the collecting cup so as not to interfere with an erupting geyser in a center portion of the collecting cup.
  • the feed tube in FIG. 1 has been rotated from that of FIG. 2 to better show the tubes internal structure.
  • FIGS. 4, 5 and 6 the feed tube of this invention is shown in enlarged sectional proportions so that its features may be readily visible.
  • This rigid thermoplastic tube with its orifices 23 and 24 provide smooth liquid flow into the nebulizing chamber. These orifices are of fixed diameters within the rigid feed tube and thus do not depend on the variations caused by manually adjusting an orifice size.
  • the rigid dual lumen feed tube can be supplied to a hospital already connected to flexible leads 3 and 4.
  • a nurse needs merely to connect leads 3 and 4 to a liquid supply bottle and insert the feed tube into a nebulizer container 5. This will supply a constant liquid feed to the nebulizer chamber 5 to replace liquid that is nebulized and consumed by the patient.
  • An anti-surging dual-lumen liquid feed assembly in combination with a nebulizer system comprising a gravity-feed liquid-supply source and a container having a pool of medical liquid below and fed by the supply source and in which the level of liquid in the pool is substantially maintained, said antisurging assembly comprising:
  • an elongated drain-tube lumen including means for connection to the liquid-supply source for the free flow of liquid therefrom,
  • drain-tube lumen including a lower terminal end portion normally immersed in said pool of liquid for supplementing the liquid in the pool;
  • said air-return lumen having a cross-sectional area substantially greater than that of the drain-tube lumen capacity whereby a greater amount of air is immediately available to replace liquid dispensed from the liquid-supply source to said pool than can be dispensed through the drain-tube lumen, each of the cross-sectional areas of said airreturn and drain-tube lumen being greater than a capilary size;
  • orifice means interposed between the lower open end of said air-return lumen and the means connected and communicating with the liquid-supply source whereby air replacing liquid in the liquid supply source passes through the liquid-supply source and is substantially dampened in its passage therethrough, said orifice means defining a constriction for limiting the size of bubbles of air passing into the source of liquid-supply.
  • drain-tube lumen includes constricted orifice means adjacent the lower end thereof.
  • said integralunit includes an integral adapter cap having a depending skirt integral with a transverse top wall for removable accomodation on a cooperating connector of the container, said top wall including integral tubular connectors for attachment to the liquid-supply source.

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Special Spraying Apparatus (AREA)
  • Medicinal Preparation (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
US00214796A 1972-01-03 1972-01-03 Continuous feed medical nebulizer Expired - Lifetime US3746000A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US21479672A 1972-01-03 1972-01-03

Publications (1)

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US3746000A true US3746000A (en) 1973-07-17

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Application Number Title Priority Date Filing Date
US00214796A Expired - Lifetime US3746000A (en) 1972-01-03 1972-01-03 Continuous feed medical nebulizer

Country Status (10)

Country Link
US (1) US3746000A (US20100056889A1-20100304-C00004.png)
JP (1) JPS4874090A (US20100056889A1-20100304-C00004.png)
AU (1) AU465224B2 (US20100056889A1-20100304-C00004.png)
BE (1) BE791693A (US20100056889A1-20100304-C00004.png)
CA (1) CA976451A (US20100056889A1-20100304-C00004.png)
ES (1) ES409700A1 (US20100056889A1-20100304-C00004.png)
FR (1) FR2166359A1 (US20100056889A1-20100304-C00004.png)
GB (1) GB1359280A (US20100056889A1-20100304-C00004.png)
IT (1) IT973971B (US20100056889A1-20100304-C00004.png)
TR (1) TR17830A (US20100056889A1-20100304-C00004.png)

Cited By (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3892235A (en) * 1971-07-27 1975-07-01 Respiratory Care Multi-use inhalation therapy apparatus
US4036919A (en) * 1974-06-26 1977-07-19 Inhalation Therapy Equipment, Inc. Nebulizer-humidifier system
US4113809A (en) * 1977-04-04 1978-09-12 Champion Spark Plug Company Hand held ultrasonic nebulizer
EP0173334A1 (en) * 1984-08-29 1986-03-05 Omron Tateisi Electronics Co. Ultrasonic atomizer
US4669480A (en) * 1985-10-16 1987-06-02 Murray Electronics Associates Limited Partnership Temperature indicating electrotherapy electrode/coil and method of use
GB2206803A (en) * 1985-06-21 1989-01-18 Kendall & Co Feeding system
US4926856A (en) * 1985-06-21 1990-05-22 Hudson Oxygen Therapy Sales Company Feeding system
US4967741A (en) * 1988-03-21 1990-11-06 Hudson Respiratory Care Inc. Retaining device
US5139016A (en) * 1987-08-07 1992-08-18 Sorin Biomedica S.P.A. Process and device for aerosol generation for pulmonary ventilation scintigraphy
US5277175A (en) * 1991-07-12 1994-01-11 Riggs John H Continuous flow nebulizer apparatus and method, having means maintaining a constant-level reservoir
US5329939A (en) * 1992-12-11 1994-07-19 Cimco, Inc. Humidifier with liquid level control
US5511539A (en) * 1995-06-19 1996-04-30 Lien; Su-Chu Dose inhaler
US5515841A (en) * 1993-11-25 1996-05-14 Minnesota Mining And Manufacturing Company Inhaler
WO1998006450A1 (en) 1996-08-16 1998-02-19 University Of Massachusetts Balloon catheter with visible or magnetic marker
USRE36070E (en) * 1993-11-09 1999-02-02 Mefar S.P.A. Micronized spray device
US6283118B1 (en) * 1999-10-13 2001-09-04 Hsueh-Yu Lu Ultrasonic nebulizer
US8042536B1 (en) * 2006-10-18 2011-10-25 Care 2 Medical Nebulizer apparatus
CN104853791A (zh) * 2013-01-09 2015-08-19 欧姆龙健康医疗事业株式会社 超声波式吸入器用的药液槽和药液封装体
WO2019016501A1 (en) * 2017-07-17 2019-01-24 Keymed (Medical & Industrial Equipment) Limited MEDICAL GAS SUPPLY SYSTEM
US10905837B2 (en) 2015-04-02 2021-02-02 Hill-Rom Services Pte. Ltd. Respiratory therapy cycle control and feedback
US11497879B2 (en) * 2013-03-15 2022-11-15 ResMed Pty Ltd Humidifier reservoir

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5416193U (US20100056889A1-20100304-C00004.png) * 1977-07-01 1979-02-01
GB2500588B (en) 2012-03-24 2017-02-01 Rhinocare Ltd Systems and methods of hyperthermal treatment
CN107233649B (zh) * 2017-08-08 2019-11-12 张红云 一种多方位内科临床消毒装置

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1972962A (en) * 1933-05-08 1934-09-11 Weber Max Constant level apparatus
DE821686C (de) * 1948-10-29 1951-11-19 Luedin & Cie Vorrichtung zur Speisung von OElbrennern
DE1056065B (de) * 1955-03-05 1959-04-23 Siemens Ag Einrichtung zum Zerstaeuben von Fluessigkeiten
US3049918A (en) * 1960-03-11 1962-08-21 Theodore Gregory Fluid flowmeters
DE1498478A1 (de) * 1964-10-28 1969-03-13 Whitmoyer Reed Ltd Vorrichtung zum Abgeben und Mischen von Fluessigkeiten in vorbestimmten relativen Mengenverhaeltnissen

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1972962A (en) * 1933-05-08 1934-09-11 Weber Max Constant level apparatus
DE821686C (de) * 1948-10-29 1951-11-19 Luedin & Cie Vorrichtung zur Speisung von OElbrennern
DE1056065B (de) * 1955-03-05 1959-04-23 Siemens Ag Einrichtung zum Zerstaeuben von Fluessigkeiten
US3049918A (en) * 1960-03-11 1962-08-21 Theodore Gregory Fluid flowmeters
DE1498478A1 (de) * 1964-10-28 1969-03-13 Whitmoyer Reed Ltd Vorrichtung zum Abgeben und Mischen von Fluessigkeiten in vorbestimmten relativen Mengenverhaeltnissen

Cited By (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3892235A (en) * 1971-07-27 1975-07-01 Respiratory Care Multi-use inhalation therapy apparatus
US4036919A (en) * 1974-06-26 1977-07-19 Inhalation Therapy Equipment, Inc. Nebulizer-humidifier system
US4113809A (en) * 1977-04-04 1978-09-12 Champion Spark Plug Company Hand held ultrasonic nebulizer
US4793339A (en) * 1984-08-29 1988-12-27 Omron Tateisi Electronics Co. Ultrasonic atomizer and storage bottle and nozzle therefor
EP0173334A1 (en) * 1984-08-29 1986-03-05 Omron Tateisi Electronics Co. Ultrasonic atomizer
GB2206803A (en) * 1985-06-21 1989-01-18 Kendall & Co Feeding system
GB2208608A (en) * 1985-06-21 1989-04-12 Kendall & Co Feeding system
GB2206803B (en) * 1985-06-21 1989-07-26 Kendall & Co Feeding system
GB2177006B (en) * 1985-06-21 1989-07-26 Kendall & Co Feeding system
GB2208608B (en) * 1985-06-21 1989-07-26 Kendall & Co Feeding system
US4926856A (en) * 1985-06-21 1990-05-22 Hudson Oxygen Therapy Sales Company Feeding system
US4669480A (en) * 1985-10-16 1987-06-02 Murray Electronics Associates Limited Partnership Temperature indicating electrotherapy electrode/coil and method of use
US5139016A (en) * 1987-08-07 1992-08-18 Sorin Biomedica S.P.A. Process and device for aerosol generation for pulmonary ventilation scintigraphy
US4967741A (en) * 1988-03-21 1990-11-06 Hudson Respiratory Care Inc. Retaining device
US5277175A (en) * 1991-07-12 1994-01-11 Riggs John H Continuous flow nebulizer apparatus and method, having means maintaining a constant-level reservoir
US5329939A (en) * 1992-12-11 1994-07-19 Cimco, Inc. Humidifier with liquid level control
USRE36070E (en) * 1993-11-09 1999-02-02 Mefar S.P.A. Micronized spray device
US5515841A (en) * 1993-11-25 1996-05-14 Minnesota Mining And Manufacturing Company Inhaler
US5511539A (en) * 1995-06-19 1996-04-30 Lien; Su-Chu Dose inhaler
WO1998006450A1 (en) 1996-08-16 1998-02-19 University Of Massachusetts Balloon catheter with visible or magnetic marker
US6283118B1 (en) * 1999-10-13 2001-09-04 Hsueh-Yu Lu Ultrasonic nebulizer
US8042536B1 (en) * 2006-10-18 2011-10-25 Care 2 Medical Nebulizer apparatus
CN104853791A (zh) * 2013-01-09 2015-08-19 欧姆龙健康医疗事业株式会社 超声波式吸入器用的药液槽和药液封装体
US9814847B2 (en) 2013-01-09 2017-11-14 Omron Healthcare Co., Ltd. Drug solution tank and drug solution pack for ultrasonic inhaler
US11497879B2 (en) * 2013-03-15 2022-11-15 ResMed Pty Ltd Humidifier reservoir
US10905837B2 (en) 2015-04-02 2021-02-02 Hill-Rom Services Pte. Ltd. Respiratory therapy cycle control and feedback
US10905836B2 (en) 2015-04-02 2021-02-02 Hill-Rom Services Pte. Ltd. Manifold for respiratory device
US11992611B2 (en) 2015-04-02 2024-05-28 Hill-Rom Services Pte. Ltd. Respiratory therapy apparatus control
WO2019016501A1 (en) * 2017-07-17 2019-01-24 Keymed (Medical & Industrial Equipment) Limited MEDICAL GAS SUPPLY SYSTEM

Also Published As

Publication number Publication date
IT973971B (it) 1974-06-10
CA976451A (en) 1975-10-21
BE791693A (fr) 1973-03-16
ES409700A1 (es) 1976-01-01
FR2166359A1 (US20100056889A1-20100304-C00004.png) 1973-08-17
GB1359280A (en) 1974-07-10
AU465224B2 (en) 1975-09-18
AU4956272A (en) 1974-06-06
TR17830A (tr) 1976-04-13
JPS4874090A (US20100056889A1-20100304-C00004.png) 1973-10-05

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AS Assignment

Owner name: BAXTER TRAVENOL LABORATORIES, INC. A CORP. OF DE

Free format text: MERGER;ASSIGNOR:AMERICAN HOSPITAL SUPPLY CORPORATION INTO;REEL/FRAME:004760/0345

Effective date: 19870126

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Owner name: BAXTER INTERNATIONAL INC., ILLINOIS

Free format text: CHANGE OF NAME;ASSIGNOR:BAXTER TRAVENOL LABORATOIRES, INC., A CORP. OF DE;REEL/FRAME:005053/0167

Effective date: 19881011

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Owner name: BAXTER INTERNATIONAL INC.

Free format text: CHANGE OF NAME;ASSIGNOR:BAXTER TRAVENOL LABORATORIES, INC., A CORP. OF DE;REEL/FRAME:005050/0870

Effective date: 19880518