US3679128A - Centrifuge - Google Patents
Centrifuge Download PDFInfo
- Publication number
- US3679128A US3679128A US61583A US3679128DA US3679128A US 3679128 A US3679128 A US 3679128A US 61583 A US61583 A US 61583A US 3679128D A US3679128D A US 3679128DA US 3679128 A US3679128 A US 3679128A
- Authority
- US
- United States
- Prior art keywords
- container
- compressible
- centrifuge
- chamber
- diaphragm
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000007788 liquid Substances 0.000 claims abstract description 21
- 239000012530 fluid Substances 0.000 claims description 22
- 238000006073 displacement reaction Methods 0.000 claims description 11
- 238000004891 communication Methods 0.000 claims description 5
- 238000000926 separation method Methods 0.000 claims description 5
- 210000004369 blood Anatomy 0.000 abstract description 20
- 239000008280 blood Substances 0.000 abstract description 20
- 238000005406 washing Methods 0.000 abstract description 16
- 210000000601 blood cell Anatomy 0.000 abstract description 12
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract description 12
- 210000002966 serum Anatomy 0.000 abstract description 9
- 238000005119 centrifugation Methods 0.000 abstract description 2
- 230000006835 compression Effects 0.000 abstract description 2
- 238000007906 compression Methods 0.000 abstract description 2
- 210000002381 plasma Anatomy 0.000 description 6
- 238000005086 pumping Methods 0.000 description 4
- 230000009471 action Effects 0.000 description 3
- 238000005192 partition Methods 0.000 description 3
- 230000008878 coupling Effects 0.000 description 2
- 238000010168 coupling process Methods 0.000 description 2
- 238000005859 coupling reaction Methods 0.000 description 2
- 239000004033 plastic Substances 0.000 description 2
- 229920003023 plastic Polymers 0.000 description 2
- 241000237074 Centris Species 0.000 description 1
- 239000004698 Polyethylene Substances 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 230000005484 gravity Effects 0.000 description 1
- 230000036512 infertility Effects 0.000 description 1
- PWPJGUXAGUPAHP-UHFFFAOYSA-N lufenuron Chemical compound C1=C(Cl)C(OC(F)(F)C(C(F)(F)F)F)=CC(Cl)=C1NC(=O)NC(=O)C1=C(F)C=CC=C1F PWPJGUXAGUPAHP-UHFFFAOYSA-N 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 239000002985 plastic film Substances 0.000 description 1
- 229920006255 plastic film Polymers 0.000 description 1
- -1 polyethylene Polymers 0.000 description 1
- 229920000573 polyethylene Polymers 0.000 description 1
- 239000003223 protective agent Substances 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
Images
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
- B04B—CENTRIFUGES
- B04B5/00—Other centrifuges
- B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
- B04B5/0407—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers for liquids contained in receptacles
- B04B5/0428—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers for liquids contained in receptacles with flexible receptacles
Definitions
- a centrifuge comprises a rotating chamber containing a com pressible container for the liquid to be centrifuged.
- the centrifuge also includes means to compress the container 'to transfer liquid from the container during centrifugation.
- the compressing means is also capable of compressing one or I more further compressible containers to transfer liquid therefrom to the first-mentioned compressible container.
- the compressing means is preferably a diaphragm member which is urged by centrifugal force against a compressible container.
- the container is filled with blood to be centrifuged and, after the serum is separated, a valve is opened permitting the diaphragm to compress the container to transfer the serum to a further container.
- the valve is then closed and speed reduced until the diaphragm returns to its rest position causing compression of a still further container provided with wash water.
- a valve is then opened to permit transfer of some or all of the wash water into the first-mentioned container and the device may then be braked to cause the water to mix with the blood cells therein.
- the washed blood cells are then centrifuged and the water transferred to the water container or yet a still further container by the actuation of an appropriate valve similarly as in the case of transferring the serum.
- the washing operation is repeated if desired until all of the wash water has been utilized.
- the invention relates to a centrifuge and particularly to a centrifuge suitable for the treatment of blood.
- a centrifuge comprising a rotor, a chamber mounted for rotation with the rotor, a compressible container located in said chamber, passage means in fluid communication with said chamber, valve means for controlling fluid flow through said passage means, and means for compressing said flexible container to decrease the volume thereof.
- FIG. I is a radial elevation section along line I in FIG. 2 through the top portion of a centrifuge according to the invention
- FIG. 2 is a schematic perspective view of the central portion of the centrifuge of FIG. 1 showing the course of conduits;
- FIG. 3 is a schematic expanded perspective view showing connections between containers provided in the centrifuge of FIG. I;
- FIG. 4 is a diagram illustrating the control of fluid flow between the containers.
- FIG. 1 is a radial section of a centrifuge according to the invention to which correspond similar sections at 120 and 240 distance, as can be seen in FIG. 2.
- a bottom disc 2 On the central portion 1 of the centrifuge rotor is fitted a bottom disc 2 and on this an outer ring 3, which has inside it three rectangular threads with three entrances.
- a top disc 4 is fixed on a threaded inner ring 5, whose threads match those of the outer ring 3.
- the outer volume of the centrifuge formed in this manner is divided into two chambers by a control device 6. This has a rigid conical partition wall 7 which is penetrated by an opening 8.
- the control device can be raised and lowered within the centrifuge rotor through the presence on it of three plugs 13 which fit into the threads of the ring 3 and can so be adjusted up and down by twisting.
- a compressible blood container 17 is arranged between the top disc 4 and the control device 6.
- the container 17 is covered by a conforming plastic disc 18 with a number of ridges 19.
- the compressible containers areannular in shape and conveniently made of polyethylene or other plastic film inert to blood. Details of a preferred bag are disclosed in US. application Ser. No. 61,574, filed Aug. 6, 1970 titled Container for Blood herein incorporated by reference.
- a screen 20 surrounds a narrower part of the central portion 1 of the centrifuge rotor.
- a slot 21 is provided in screen 20 through which flexible tubes 14', 15', 16 connected to the containers l4, l5, 16 are introduced into the space between rotor l and the screen 20.
- Each tube l4, 15', 16' connects its respective container with container 17 and each is provided with a valve 14", 15", and 16" to control the flow of fluid between container 17 and each container l4, l5, and 16.
- Valve 16" is visible in FIG. 1 and comprises an electro magnet 22 which acts on a valve arm 23, which forms a loop in which is inserted the line 16, so that the line is closed when the magnet is activated. Electromagnet 22 is actuated by electrical leads 22 in a conventional manner. When current is broken, line 16 is free, and the release of the line can be assisted by a spring 22". These details are conventional and can obviously be varied in a number of different ways.
- FIG. 4 shows schematically how a program register 24 is arranged for the control of the operation of the centrifuge 25 through lines to the valves 14'', 15', 16" and to a brake 26, which may be any suitable electrically controlled brake. It should be noted that the valves l4", 15'', 16" are opened when the magnets are currentless.
- Container I4 is filled with 5 X 250 1,250 ml of washing liquor.
- Containers l5 and 16 are empty.
- Containers 14, l5, and 16 are placed in the lower chamber of the centrifuge on the bottom disc 2, as can be seen in FIG. 1.
- the three connecting lines or flexible tubes are placed around the central portion 1, as shown in FIG. 2 and clamped tight at the valve devices 14", 15'', 16''.
- Control device 6 is now threaded in until practically all the air has been driven out from the lower centrifuge space. Control device 6 has then reached its bottom position, and the displacement fluid (250 ml) in cavity 12 is below partition wall 7. Owing to the substantial diaphragm stress it is not possible by hand to press the displacement fluid up through the opening 8. Control device 6 is locked in this position by any suitable known device, for example, a locking screw, which is not shown in the drawings.
- the blood container 17 and the disc 18 are inserted, whereupon the three connecting lines to container 17 are joined together with three lines from the containers l4, l5, 16 as shown in FIG. 3.
- the top disc 4 of the centrifugal rotor with ring 5 is screwed down into position as shown and locked in a suitable manner.
- the centrifuge can now be started, and approximately three minutes after it has reached the steady state with approximately 1,000 g in the periphery, the blood corpuscles have been packed together and the plasma, which constitutes approximately half the volume, can be conveyed to empty container 16.
- valve 16" is opened.
- the heavy diaphragm 10 whose centrifugal force is greater than the diaphragm stresses, drives the displacement fluid through the opening 8.
- the program register closes valve 16" and opens valve 14'', so that a connection is established between the containers 17 and 14.
- the brake is now released and the centrifuge is re-started. Approximately 3 minutes after the steady state has been attained, the blood corpuscles have again been packed together and the liquor can be tapped. This is done by opening valve 15', so that the consumed washing liquor is conveyed to the container 15 in the same manner as described above for the transport of plasma to container 16. The washing process is repeated five times whereupon the centrifuge is stopped.
- the result is that the blood corpuscles have been thoroughly washed and a minimum of washing liquor remains in the blood container 17.
- the plasma has been conveyed to the plasma container 16 and the washing liquor to the discharge container 14.
- the displacement fluid which at the beginning was in the lower part of control device 16 is now in the top part thereof and the bottom part is consequently exposed to a substantial overpressure caused by the diaphragm stresses.
- the top part 4 is screwed off.
- the blood container 17 is detached from the connecting lines and the plastic disc 18 is taken off.
- the connecting tube of the discharge container is connected up to a discharge and the valve 15" is opened.
- 250 ml consumed washing liquor runs off, so that the displacement fluid drops down into the bottom part.
- the overpressure in the bottom part disappears, and the centrifuge can be dismantled.
- control device 6 may be exercised by means of a pressure variation across the control device brought about, for example, by sealing off of the chamber where the blood container is situated and supply of the pumping pressure to that chamber via a rotating coupling.
- Such a centrifuge operates in the same manner as the one described above, except that at least one of the chambers of the centrifuge must be in airtight separation from the at mosphere environment as well as from the other chamber.
- the pumping action from the one chamber to the other chamber is not obtained through variation of speed, but
- Centrifuges in accordance with the invention are intended in the first place to be used for the treatment of one blood unit at a time, but it will be apparent that it is quite possible to stackon the same axle a number of compressible containers.
- a centrifuge comprising:
- At least one further compressible container located in said second chamber
- passage means placing said first compressible container in fluid communication with said further compressible container
- valve means for controlling the flow of fluid through said passage means
- a second diaphragm spaced from said first diaphragm and including a cavity therebetween;
- said flexible diaphragms being inclined with respect to the axis of rotation of said rotor such that, at a certain rotational speed, said diaphragms are urged from a rest position to a high speed position compressing said one compressible container.
- a centrifuge according to claim 1 including a plurality of further compressible containers each in fluid communication with said first compressible container through said passage means, said valve means controlling the fluid flow between said first compressible container and each of said further compressible containers.
- a centrifuge according to claim 5 wherein said first container includes a liquid to be centrifuged, and said further compressible containers comprise a container for receiving a phase separated from the centrifugal liquid, a container for wash liquid to be introduced into said first container after separation of said phase, and a container for receiving wash liquid from said first container, said centrifuge including means for arresting motion of said first chamber whereby said wash liquid is mixed with the phase in said first container.
Landscapes
- External Artificial Organs (AREA)
- Centrifugal Separators (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE1112169A SE332906B (xx) | 1969-08-11 | 1969-08-11 |
Publications (1)
Publication Number | Publication Date |
---|---|
US3679128A true US3679128A (en) | 1972-07-25 |
Family
ID=20293390
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US61583A Expired - Lifetime US3679128A (en) | 1969-08-11 | 1970-08-06 | Centrifuge |
Country Status (8)
Country | Link |
---|---|
US (1) | US3679128A (xx) |
JP (1) | JPS4936599B1 (xx) |
BE (1) | BE754682A (xx) |
DE (1) | DE2039897B2 (xx) |
FR (1) | FR2056830A5 (xx) |
GB (1) | GB1329606A (xx) |
NL (1) | NL7011835A (xx) |
SE (1) | SE332906B (xx) |
Cited By (33)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3737096A (en) * | 1971-12-23 | 1973-06-05 | Ibm | Blood processing control apparatus |
US3858796A (en) * | 1971-03-15 | 1975-01-07 | Hans Peter Olof Unger | Container for use in treatment of liquid |
US3987961A (en) * | 1974-01-29 | 1976-10-26 | Heraeus-Christ Gmbh | Centrifuge bag for treatment of biological liquids |
US4007871A (en) * | 1975-11-13 | 1977-02-15 | International Business Machines Corporation | Centrifuge fluid container |
WO1980001470A1 (en) * | 1979-01-22 | 1980-07-24 | Haemonetics Corp | Apparatus for separating blood into components thereof |
US4304357A (en) * | 1980-06-16 | 1981-12-08 | Haemonetics Corporation | Blood processing centrifuge |
US4344560A (en) * | 1979-11-02 | 1982-08-17 | Asahi Kasei Kogyo Kabushiki Kaisha | Container, apparatus and method for separating platelets |
US4402680A (en) * | 1981-07-09 | 1983-09-06 | Haemonetics Corporation | Apparatus and method for separating fluid into components thereof |
US4405079A (en) * | 1980-11-10 | 1983-09-20 | Haemonetics Corporation | Centrifugal displacer pump |
US4417884A (en) * | 1981-07-09 | 1983-11-29 | Haemonetics Corporation | Centrifuge timer clamp |
US4421503A (en) * | 1981-07-09 | 1983-12-20 | Haemonetics Corporation | Fluid processing centrifuge and apparatus thereof |
WO1987006857A1 (en) * | 1986-05-16 | 1987-11-19 | Omega Medicinteknik Ab | Annular centrifuge |
WO1989002273A1 (en) * | 1987-09-15 | 1989-03-23 | Omega Medicinteknik Ab | Method of washing blood cells and container assembly therefor |
US5672481A (en) * | 1991-10-23 | 1997-09-30 | Cellpro, Incorporated | Apparatus and method for particle separation in a closed field |
US6261217B1 (en) * | 1997-04-16 | 2001-07-17 | Sanguistech Aktiebolag | Separation set having plate-like separation container with annular pinch valve for blood component preparation |
US6656105B2 (en) | 1999-05-31 | 2003-12-02 | Gambro, Inc. | Centrifuge for processing blood and blood components in ring-type blood processing bags |
US6689042B2 (en) | 1997-02-12 | 2004-02-10 | Gambro, Inc. | Centrifuge and container system for treatment of blood and blood components |
US6740239B2 (en) | 1999-10-26 | 2004-05-25 | Gambro, Inc. | Method and apparatus for processing blood and blood components |
US20040104182A1 (en) * | 2002-04-16 | 2004-06-03 | Gambro, Inc. | Methods and apparatuses for blood component separation |
US6855102B2 (en) * | 1996-02-26 | 2005-02-15 | Gambro Inc | Method for separating cells, especially platelets, and bag assembly therefor |
US20050045567A1 (en) * | 2003-08-25 | 2005-03-03 | Gambro, Inc. | Apparatus and method for separating a volume of composite liquid into at least two components |
US20070203444A1 (en) * | 2004-12-28 | 2007-08-30 | Gambro Bct, Inc. | Apparatus and Method for Separating a Volume of Whole Blood Into At Least Three Components |
US20070209708A1 (en) * | 2004-06-22 | 2007-09-13 | Gambro, Inc. | Bag Assembly for the Separation of a Composite Liquid and Method for Manufacturing it |
US20070284320A1 (en) * | 2006-06-07 | 2007-12-13 | Gambro Bct, Inc. | Apparatus and Method for Separating a Composite Liquid Into At Least Two Components |
US20080053203A1 (en) * | 2006-09-06 | 2008-03-06 | Gambro Bct, Inc. | Apparatus and Method for Separating A Composite Liquid Into At Least Two Components |
US20080149564A1 (en) * | 2006-12-20 | 2008-06-26 | Gambro Bct, Inc. | Apparatus and Method for Separating a Composite Liquid Into At Least Two Components |
US20080220959A1 (en) * | 2005-08-22 | 2008-09-11 | Gambro Bct, Inc. | Apparatus and Method for Separating A Composite Liquid Into At Least Two Components |
US20080283473A1 (en) * | 2007-05-14 | 2008-11-20 | Gambro Bct, Inc. | Apparatus and Method for Separating a Composite Liquid Into At Least Two Components |
US20100026986A1 (en) * | 2008-07-31 | 2010-02-04 | Caridianbct, Inc. | Method and Apparatus for Separating A Composite Liquid Into At Least Two Components And For Determining The Yield Of At Least One Component |
CN101444763B (zh) * | 2008-11-25 | 2010-12-08 | 康炜 | 全自动血液成分制备装置及制备方法 |
CN101306404B (zh) * | 2008-07-04 | 2011-09-07 | 康炜 | 血液成分制备装置及制备方法 |
US9028388B2 (en) | 2010-06-07 | 2015-05-12 | Terumo Bct, Inc. | Multi-unit blood processor with volume prediction |
US9079194B2 (en) | 2010-07-19 | 2015-07-14 | Terumo Bct, Inc. | Centrifuge for processing blood and blood components |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE354581B (xx) * | 1971-03-15 | 1973-03-19 | Aga Ab | |
DE4340678C2 (de) * | 1993-11-30 | 2000-07-06 | Hettich Andreas Gmbh & Co Kg | Zentrifuge zur Trennung von Blutbestandteilen und ähnlichen Flüssigkeiten |
DE19841835C2 (de) * | 1998-09-12 | 2003-05-28 | Fresenius Ag | Zentrifugenkammer für einen Zellseparator |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2661150A (en) * | 1947-12-17 | 1953-12-01 | Jr William G Abbott | Centrifuge |
US3249295A (en) * | 1966-05-03 | Method for separating liquid mixtures |
-
1969
- 1969-08-11 SE SE1112169A patent/SE332906B/xx unknown
-
1970
- 1970-07-30 GB GB3683870A patent/GB1329606A/en not_active Expired
- 1970-08-05 JP JP45068978A patent/JPS4936599B1/ja active Pending
- 1970-08-06 US US61583A patent/US3679128A/en not_active Expired - Lifetime
- 1970-08-10 BE BE754682D patent/BE754682A/xx unknown
- 1970-08-11 NL NL7011835A patent/NL7011835A/xx unknown
- 1970-08-11 DE DE19702039897 patent/DE2039897B2/de active Granted
- 1970-08-11 FR FR7029499A patent/FR2056830A5/fr not_active Expired
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3249295A (en) * | 1966-05-03 | Method for separating liquid mixtures | ||
US2661150A (en) * | 1947-12-17 | 1953-12-01 | Jr William G Abbott | Centrifuge |
Cited By (68)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3858796A (en) * | 1971-03-15 | 1975-01-07 | Hans Peter Olof Unger | Container for use in treatment of liquid |
US3737096A (en) * | 1971-12-23 | 1973-06-05 | Ibm | Blood processing control apparatus |
US3987961A (en) * | 1974-01-29 | 1976-10-26 | Heraeus-Christ Gmbh | Centrifuge bag for treatment of biological liquids |
US4007871A (en) * | 1975-11-13 | 1977-02-15 | International Business Machines Corporation | Centrifuge fluid container |
WO1980001470A1 (en) * | 1979-01-22 | 1980-07-24 | Haemonetics Corp | Apparatus for separating blood into components thereof |
JPS55501133A (xx) * | 1979-01-22 | 1980-12-18 | ||
US4303193A (en) * | 1979-01-22 | 1981-12-01 | Haemonetics Corporation | Apparatus for separating blood into components thereof |
US4344560A (en) * | 1979-11-02 | 1982-08-17 | Asahi Kasei Kogyo Kabushiki Kaisha | Container, apparatus and method for separating platelets |
WO1981003626A1 (en) * | 1980-06-16 | 1981-12-24 | Haemonetics Corp | Blood processing centrifuge |
US4304357A (en) * | 1980-06-16 | 1981-12-08 | Haemonetics Corporation | Blood processing centrifuge |
US4405079A (en) * | 1980-11-10 | 1983-09-20 | Haemonetics Corporation | Centrifugal displacer pump |
US4402680A (en) * | 1981-07-09 | 1983-09-06 | Haemonetics Corporation | Apparatus and method for separating fluid into components thereof |
US4417884A (en) * | 1981-07-09 | 1983-11-29 | Haemonetics Corporation | Centrifuge timer clamp |
US4421503A (en) * | 1981-07-09 | 1983-12-20 | Haemonetics Corporation | Fluid processing centrifuge and apparatus thereof |
WO1987006857A1 (en) * | 1986-05-16 | 1987-11-19 | Omega Medicinteknik Ab | Annular centrifuge |
WO1989002273A1 (en) * | 1987-09-15 | 1989-03-23 | Omega Medicinteknik Ab | Method of washing blood cells and container assembly therefor |
US5114396A (en) * | 1987-09-15 | 1992-05-19 | Omega Medicinteknik Ab | Method of washing blood cells and container assembly thereof |
US5672481A (en) * | 1991-10-23 | 1997-09-30 | Cellpro, Incorporated | Apparatus and method for particle separation in a closed field |
US6855102B2 (en) * | 1996-02-26 | 2005-02-15 | Gambro Inc | Method for separating cells, especially platelets, and bag assembly therefor |
US6689042B2 (en) | 1997-02-12 | 2004-02-10 | Gambro, Inc. | Centrifuge and container system for treatment of blood and blood components |
US20040147387A1 (en) * | 1997-02-12 | 2004-07-29 | Gambro, Inc. | Centrifuge and container system for treatment of blood and blood components |
US6835171B2 (en) | 1997-02-12 | 2004-12-28 | Gambro Inc | Centrifuge and container system for treatment of blood and blood components |
US6261217B1 (en) * | 1997-04-16 | 2001-07-17 | Sanguistech Aktiebolag | Separation set having plate-like separation container with annular pinch valve for blood component preparation |
US20060270542A1 (en) * | 1999-05-31 | 2006-11-30 | Gambro, Inc. | Centrifuge for Processing Blood and Blood Components |
US6656105B2 (en) | 1999-05-31 | 2003-12-02 | Gambro, Inc. | Centrifuge for processing blood and blood components in ring-type blood processing bags |
US7235041B2 (en) | 1999-05-31 | 2007-06-26 | Gambro Bct, Inc. | Centrifuge for processing a blood product with a bag set having a processing bag |
US7097774B2 (en) | 1999-05-31 | 2006-08-29 | Gambro Inc | Method for processing a blood product with a bag set having a multi-way connector |
US6740239B2 (en) | 1999-10-26 | 2004-05-25 | Gambro, Inc. | Method and apparatus for processing blood and blood components |
US20070084807A1 (en) * | 2002-04-16 | 2007-04-19 | Gambro, Inc. | Methods and Apparatus for Blood Component Separation |
US7497944B2 (en) | 2002-04-16 | 2009-03-03 | Caridianbct, Inc. | Blood component processing system, apparatus, and method |
US20080314822A1 (en) * | 2002-04-16 | 2008-12-25 | Gambro Bct, Inc. | Apparatus for Blood Component Separation |
US20070084806A1 (en) * | 2002-04-16 | 2007-04-19 | Gambro, Inc. | Methods and Apparatus for Blood Component Separation |
US7166217B2 (en) | 2002-04-16 | 2007-01-23 | Gambro Inc | Methods and apparatuses for blood component separation |
US7708889B2 (en) | 2002-04-16 | 2010-05-04 | Caridianbct, Inc. | Blood component processing system method |
US20040104182A1 (en) * | 2002-04-16 | 2004-06-03 | Gambro, Inc. | Methods and apparatuses for blood component separation |
US7279107B2 (en) | 2002-04-16 | 2007-10-09 | Gambro, Inc. | Blood component processing system, apparatus, and method |
US7413665B2 (en) | 2002-04-16 | 2008-08-19 | Gambro Bct, Inc. | Methods and apparatus for blood component separation |
US7648452B2 (en) | 2002-04-16 | 2010-01-19 | CardianBCT, Inc. | Apparatus for blood component separation |
US7396451B2 (en) | 2002-04-16 | 2008-07-08 | Gambo Bci, Inc. | Methods and apparatus for blood component separation |
US20050045567A1 (en) * | 2003-08-25 | 2005-03-03 | Gambro, Inc. | Apparatus and method for separating a volume of composite liquid into at least two components |
US20080093312A1 (en) * | 2003-08-25 | 2008-04-24 | Gambro Bct, Inc. | Method for Separating A Volume of Composite Liquid Into At Least Two Components |
US7347932B2 (en) | 2003-08-25 | 2008-03-25 | Gambro Bct, Inc. | Apparatus and method for separating a volume of composite liquid into at least two components |
US7648639B2 (en) | 2003-08-25 | 2010-01-19 | CaridianBCT, Inc | Method for separating a volume of composite liquid into at least two components |
US20070209708A1 (en) * | 2004-06-22 | 2007-09-13 | Gambro, Inc. | Bag Assembly for the Separation of a Composite Liquid and Method for Manufacturing it |
US20070203444A1 (en) * | 2004-12-28 | 2007-08-30 | Gambro Bct, Inc. | Apparatus and Method for Separating a Volume of Whole Blood Into At Least Three Components |
US8277406B2 (en) | 2004-12-28 | 2012-10-02 | Terumo Bct, Inc. | Method for separating a volume of whole blood into at least three components |
US7833185B2 (en) | 2004-12-28 | 2010-11-16 | Caridianbct, Inc. | Apparatus for separating a volume of whole blood into at least three components |
US7981019B2 (en) | 2005-08-22 | 2011-07-19 | Caridianbct, Inc. | Apparatus and method for separating a composite liquid into at least two components |
US20080220959A1 (en) * | 2005-08-22 | 2008-09-11 | Gambro Bct, Inc. | Apparatus and Method for Separating A Composite Liquid Into At Least Two Components |
US8057377B2 (en) | 2005-08-22 | 2011-11-15 | CaridianBCT, Inc | Apparatus and method for separating a composite liquid into at least two components |
US20110077140A1 (en) * | 2005-08-22 | 2011-03-31 | Gambro Bct, Inc. | Apparatus and Method for Separating A Composite Liquid Into At Least Two Components |
US20110028295A1 (en) * | 2006-06-07 | 2011-02-03 | Caridianbct, Inc. | Apparatus for Separating a Composite Liquid Into At Least Two Components |
US20070284320A1 (en) * | 2006-06-07 | 2007-12-13 | Gambro Bct, Inc. | Apparatus and Method for Separating a Composite Liquid Into At Least Two Components |
US7819793B2 (en) | 2006-06-07 | 2010-10-26 | Caridianbct, Inc. | Apparatus for separating a composite liquid into at least two components |
US20080053203A1 (en) * | 2006-09-06 | 2008-03-06 | Gambro Bct, Inc. | Apparatus and Method for Separating A Composite Liquid Into At Least Two Components |
US8173027B2 (en) | 2006-09-06 | 2012-05-08 | Terumo Bct, Inc. | Method of separating a composite liquid into at least two components |
US8287742B2 (en) * | 2006-12-20 | 2012-10-16 | Terumo Bct, Inc. | Method for separating a composite liquid into at least two components |
CN101557843B (zh) * | 2006-12-20 | 2012-05-02 | 科安比司特公司 | 将复合液体分离成至少两种成分的设备和方法 |
US20080149564A1 (en) * | 2006-12-20 | 2008-06-26 | Gambro Bct, Inc. | Apparatus and Method for Separating a Composite Liquid Into At Least Two Components |
US20080283473A1 (en) * | 2007-05-14 | 2008-11-20 | Gambro Bct, Inc. | Apparatus and Method for Separating a Composite Liquid Into At Least Two Components |
US8236184B2 (en) | 2007-05-14 | 2012-08-07 | Terumo Bct, Inc. | Method for separating a composite liquid into at least two components |
CN101306404B (zh) * | 2008-07-04 | 2011-09-07 | 康炜 | 血液成分制备装置及制备方法 |
US20100026986A1 (en) * | 2008-07-31 | 2010-02-04 | Caridianbct, Inc. | Method and Apparatus for Separating A Composite Liquid Into At Least Two Components And For Determining The Yield Of At Least One Component |
US8120760B2 (en) | 2008-07-31 | 2012-02-21 | Caridianbct, Inc. | Method and apparatus for separating a composite liquid into at least two components and for determining the yield of at least one component |
CN101444763B (zh) * | 2008-11-25 | 2010-12-08 | 康炜 | 全自动血液成分制备装置及制备方法 |
US9028388B2 (en) | 2010-06-07 | 2015-05-12 | Terumo Bct, Inc. | Multi-unit blood processor with volume prediction |
US9849222B2 (en) | 2010-06-07 | 2017-12-26 | Terumo Bct, Inc. | Multi-unit blood processor with volume prediction |
US9079194B2 (en) | 2010-07-19 | 2015-07-14 | Terumo Bct, Inc. | Centrifuge for processing blood and blood components |
Also Published As
Publication number | Publication date |
---|---|
NL7011835A (xx) | 1971-02-15 |
DE2039897B2 (de) | 1973-01-18 |
BE754682A (fr) | 1971-01-18 |
JPS4936599B1 (xx) | 1974-10-02 |
SE332906B (xx) | 1971-02-22 |
GB1329606A (en) | 1973-09-12 |
FR2056830A5 (xx) | 1971-05-14 |
DE2039897A1 (de) | 1971-03-18 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US3679128A (en) | Centrifuge | |
US6261217B1 (en) | Separation set having plate-like separation container with annular pinch valve for blood component preparation | |
US4285464A (en) | Apparatus for separation of blood into components thereof | |
EP0014093B1 (en) | An apparatus, a method and a disposable blood pathway for use in separating blood into components thereof | |
US6641552B1 (en) | Blood collection and separation system | |
EP0301077B1 (en) | Plasma collection set and method | |
US4405079A (en) | Centrifugal displacer pump | |
US5114396A (en) | Method of washing blood cells and container assembly thereof | |
US4296882A (en) | Centrifugal fluid processing device | |
US4091989A (en) | Continuous flow fractionation and separation device and method | |
US4859333A (en) | Continous blood centrifugation cell | |
US4402680A (en) | Apparatus and method for separating fluid into components thereof | |
US6652475B1 (en) | Automated blood component separation system | |
WO1987006857A1 (en) | Annular centrifuge | |
US20140323284A1 (en) | Automated System and Method for Blood Components Separation and Processing | |
US20110003675A1 (en) | Apparatus and Method for Automatically Loading Washing Solution In A Multi-Unit Blood Processor | |
JPH01502560A (ja) | 血漿搬出方法およびその装置 | |
US5547108A (en) | Expressor | |
US3559880A (en) | Apparatus for blood plasma separation | |
US3133881A (en) | Apparatus for separating liquid mixtures | |
US6780333B1 (en) | Centrifugation pheresis method | |
CA1185218A (en) | Centrifugal separation of platelet rich plasma |