US3674006A - Appliance for interstitial radiation of organs in the body - Google Patents

Appliance for interstitial radiation of organs in the body Download PDF

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Publication number
US3674006A
US3674006A US3674006DA US3674006A US 3674006 A US3674006 A US 3674006A US 3674006D A US3674006D A US 3674006DA US 3674006 A US3674006 A US 3674006A
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Prior art keywords
rod
sheath
end
radioactive compound
handle
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Expired - Lifetime
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Bernt Arne Gustaf Holmer
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Studsvik Energiteknik AB
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Studsvik Energiteknik AB
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1001X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
    • A61N5/1027Interstitial radiation therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1001X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
    • A61N5/1007Arrangements or means for the introduction of sources into the body
    • A61N2005/1011Apparatus for permanent insertion of sources

Abstract

An appliance for the interstitial radiation of organs in the body of man or animals comprises a cannular tube which contains a radioactive compound and which is attached to the end of a rod provided with a handle. A sheath can be adjustably displaced along the cannular tube and rod and is arranged to tightly surround the tube and rod. The sheath is radiation-absorbing at least at the outer part, which can be brought to cover, more or less, the radioactive compound in the cannular tube.

Description

United States Patent Holmer 45] July4, 1972 [54] APPLIANCE FOR INTERSTITIAL RADIATION OF ORGANS IN THE BODY [72] Inventor: Bemt Arne Gustaf Holmer, Nykoping,

Sweden [73] Assignee: Aktiebolaget Atomenergi, Stockholm,

Sweden [22] Filed: May 1,1969

21 Appl. No.: 820,740

[30] Foreign Application Priority Data Kunkle ..128/l.2

1,867,624 7/1932 Hoffman 128/12 UX 2,546,761 3/1951 Loftus ..128/1.2

3,480,778 11/1969 Meedcr et a1 ..250/108 FOREIGN PATENTS OR APPLICATIONS 857,992 1/1961 Great Britain ..128/l.2

Primary ExaminerWilliam E. Kamm AttarneyMcGlew and Toren [5 7] ABSTRACT An appliance for the interstitial radiation of organs in the body of man or animals comprises a cannular tube which contains a radioactive compound and which is attached to the end of a rod provided with a handle. A sheath can be adjustably displaced along the cannular tube and rod and is arranged to tightly surround the tube and rod. The sheath is radiation-absorbing at least at the outer part, which can be brought to cover, more or less, the radioactive compound in the cannular tube.

2 Claims, 3 Drawing Figures APPLIANCE FOR INTERSTITIAL RADIATION OF ORGANS IN THE BODY The invention relates to an improvement in appliances with cannular, tubes for interstitial radiation of organs in the body of man and animals. Such an instrument, which has come into use particularly with radiation of the pituitary gland with Sr, is described in Fortschritte auf dem Gebiete der Riintgenstrahlen und der Nuldearmedizin, Bd 106 (1967) pp. 574-578. It consists of a shaft 2 mm wide and approximately 25 cm long provided with a handle 2 the end of the shaft, a cannular tube 1 mm wide and 30 mm long of stainless steel having a material thickness of 0.14 mm, which isplugged at the outer end with a steel plug 1 mm long and has a 4.5 mm length of stron urn sulphate containing Sr packed between the steel plug and a 3 mm long plug of indium which fits tightly against the tube wall. This instrument offers considerable advantages for radiological therapy over conventional methods with inserts of Y or Au, for example.

The object of the invention is to improve the known type of appliance by making the radiation adjustable.

Y The appliance according to the invention comprises a cannular tube containing a radioactive compound and beingattached at the end of a rod provided with a handle and is characterized by a sheath which can be adjustably displaced along the cannular tube and rod and suitably tightly surrounds these, said sheath being radiation-absorbing at least at the outer part corresponding to the length of the compound in the cannular tube. The sheath is suitably joined to the rod or the handle by means of threading. On grading or scale on which can be read with an index how much of the compound in the cannular tube projects outside the sheath. Between the indium tube is suitably filled with a spacer less steel, so that the cannular tube is strengthened.

One embodiment of the appliance is shown in the accompanying drawings where FIG. 1 shows the appliance in its entirety,

FIG. 2 is an enlarged illustration of the point of the appliance and FIG. 3 is an enlarged illustration of the handle and adjacent portion of the sheath.

The cannular tube 3 is attached 7 indicated in the drawing, provided with a handle 1. The tube has an outer plug 4 and an inner plug 5 which enclose a compound filling 6. The inner part of the cannular tube is filled by a spacer rod 7. A sheath l0 acting as diaphragm, which should have a material thickness of approximately 0.5 mm at least in the part which is to entirely or partly cover the compound 6, surrounds the rod 2 and the cannular tube 3 and is attached to I the handle 1 by way of a cylindrical body by means of threading (not shown) so that it can be displaced and expose a cm long and, attached at the handle there should be a to the end of the rod 2, only plug and the rod the cannular rod of, for example, stain shown on a fluorescent greater or smaller quantity of the compound filling 6. The position of the sheath can be read on the scale 12 on the cylin drical body 11 with the help of theend surface 13 of the handle which serves as an index.

\Vrth the appliance according to the invention the following advantages are gained, inter aliarlt is possible with one and the same appliance to obtain a radiation efiect along an adjustable length of the active part of the appliance, for which otherwise several radiation sources with difierent lengths must be used. The adaptability of the active part facilitates adjustment of the point of the appliance alter it has been inserted into the organ to be irradiated. When the part of the body is screen it may be found that an error of judgement has been made in determining the size of the part to be irradiated. Furthermore, handling of the applicance is much safer since the diaphragm may be permitted to cover the entire radiation source while the appliance is being handled and even during insertion into the body. In this way the ineffective exposure to radiation is reduced for the operation staff and the patient. The construction also provides appreciable reinforcement against breaking. The point of the appliance, that is the cannular tube, is in itself fragile.

What is claimed is:

l. Appliance for interstitial radiation of organs in the body of man and animals, comprising an elongated hollow rod, a radioactive compound disposed within one end of said rod, a handle fitted on the opposite end of said rod, said handle having a screw-thread formed thereon, an elongated tubular sheath being in closely fitting relationship with and enclosing at least a portion of said rod and being axially displaceable thereon, said sheath being shorter than said rod, the end of said sheath adjacent the end of said rod containing said radioactive compound including a r 'ation-absorbing material extending for at least the length of the radioactive compound in said rod, the opposite end of said sheath being arranged in threaded engagement with the screw-thread on said handle for axially displacing said sheath relative to said rod for selectively uncovering any desired length of said rod containing the radioactive compound, and scale and index means cooperatively arranged on said handle and said sheath for indicating the axial length of said rod containing the radioactive compound which projects outwardly from the radiation-absorbing end of said sheath.

2. Appliance, as set forth in claim 1 characterized in that an outer plug being fitted into the end of said rod containing the radioactive compound, an inner plug positioned within said rod at the opposite end of the radioactive compound from said outer plug, and a spacer rod extending axially from said inner plug toward the opposite end of said rod on which said handle is fitted.

* l l i

Claims (2)

1. Appliance for interstitial radiation of organs in the body of man and animals, comprising an elongated hollow rod, a radioactive compound disposed within one end of said rod, a handle fitted on the opposite end of said rod, said handle having a screw-thread formed thereon, an elongated tubular sheath being in closely fitting relationship with and enclosing at least a portion of said rod and being axially displaceable thereon, said sheath being shorter than said rod, the end of said sheath adjacent the end of said rod containing said radioactive compound including a radiation-absorbing material extending for at least the length of the radioactive compound in said rod, the opposite end of said sheath being arranged in threaded engagement with the screw-thread on said handle for axially displacing said sheath relative to said rod for selectively uncovering any desired length of said rod containing the radioactive compound, and scale and index means cooperatively arranged on said handle and said sheath for indicating the axial length of said rod containing the radioactive compound which projects outwardly from the radiationabsorbing end of said sheath.
2. Appliance, as set forth in claim 1 characterized in that an outer plug being fitted into the end of said rod containing the radioactive compound, an inner plug positioned within said rod at the opposite end of the radioactive compound from said outer plug, and a spacer rod extending axially from said inner plug toward the opposite end of said rod on which said handle is fitted.
US3674006A 1968-05-02 1969-05-01 Appliance for interstitial radiation of organs in the body Expired - Lifetime US3674006A (en)

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SE595368 1968-05-02

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US (1) US3674006A (en)
FR (1) FR2007684A1 (en)
GB (1) GB1239493A (en)

Cited By (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4086914A (en) * 1977-02-11 1978-05-02 Edwin Bailey Moore Implant injector
US4167179A (en) * 1977-10-17 1979-09-11 Mark Kirsch Planar radioactive seed implanter
US4627420A (en) * 1983-10-31 1986-12-09 Katz Harry R Needle inserting instrument for interstitial radiotherapy
US4819618A (en) * 1986-08-18 1989-04-11 Liprie Sam F Iridium/platinum implant, method of encapsulation, and method of implantation
US4957476A (en) * 1989-01-09 1990-09-18 University Of Pittsburgh Afterloading radioactive spiral implanter
US4976680A (en) * 1988-10-07 1990-12-11 Hayman Michael H Apparatus for in situ radiotherapy
US5010892A (en) * 1988-05-04 1991-04-30 Triangle Research And Development Corp. Body lumen measuring instrument
US5084002A (en) * 1988-08-04 1992-01-28 Omnitron International, Inc. Ultra-thin high dose iridium source for remote afterloader
US5092834A (en) * 1990-10-12 1992-03-03 Omnitron International, Inc. Apparatus and method for the remote handling of highly radioactive sources in the treatment of cancer
US5141487A (en) * 1985-09-20 1992-08-25 Liprie Sam F Attachment of radioactive source and guidewire in a branchy therapy source wire
US5199939A (en) * 1990-02-23 1993-04-06 Dake Michael D Radioactive catheter
US5213561A (en) * 1990-09-06 1993-05-25 Weinstein Joseph S Method and devices for preventing restenosis after angioplasty
US5683345A (en) * 1994-10-27 1997-11-04 Novoste Corporation Method and apparatus for treating a desired area in the vascular system of a patient
US5688220A (en) * 1994-06-10 1997-11-18 Schneider (Europe) A.G. Medical appliance for treatment by ionizing radiation
US5713828A (en) * 1995-11-27 1998-02-03 International Brachytherapy S.A Hollow-tube brachytherapy device
US5728042A (en) * 1995-06-22 1998-03-17 Schneider (Europe) A.G. Medical appliance for ionizing radiation treatment having radiopaque markers
US5899882A (en) * 1994-10-27 1999-05-04 Novoste Corporation Catheter apparatus for radiation treatment of a desired area in the vascular system of a patient
US5938604A (en) * 1997-05-28 1999-08-17 Capintec, Inc. Radioactive needle for biopsy localization and a method for making the radioactive needle
US6071227A (en) * 1993-07-01 2000-06-06 Schneider (Europe) A.G. Medical appliances for the treatment of blood vessels by means of ionizing radiation
US6110097A (en) * 1997-03-06 2000-08-29 Scimed Life Systems, Inc. Perfusion balloon catheter with radioactive source
US6146322A (en) * 1995-12-05 2000-11-14 Schneider (Europe) Ag Irradiating filament and method of making same
US6175760B1 (en) * 1998-02-17 2001-01-16 University Of Iowa Research Foundation Lesion localizer for nuclear medicine
US6203485B1 (en) 1999-10-07 2001-03-20 Scimed Life Systems, Inc. Low attenuation guide wire for intravascular radiation delivery
US6258019B1 (en) 1997-09-26 2001-07-10 Scimed Life Systems, Inc. Catheter for intraluminal treatment of a vessel segment with ionizing radiation
US6264596B1 (en) 1997-11-03 2001-07-24 Meadox Medicals, Inc. In-situ radioactive medical device
US6267775B1 (en) 1997-03-21 2001-07-31 Schneider (Usa) Inc. Self-expanding medical device for centering radioactive treatment sources in body vessels
US6302865B1 (en) 2000-03-13 2001-10-16 Scimed Life Systems, Inc. Intravascular guidewire with perfusion lumen
US6352501B1 (en) 1999-09-23 2002-03-05 Scimed Life Systems, Inc. Adjustable radiation source
US6398709B1 (en) 1999-10-19 2002-06-04 Scimed Life Systems, Inc. Elongated member for intravascular delivery of radiation
US6398708B1 (en) 1996-02-29 2002-06-04 Scimed Life Systems, Inc. Perfusion balloon and radioactive wire delivery system
US6416457B1 (en) 2000-03-09 2002-07-09 Scimed Life Systems, Inc. System and method for intravascular ionizing tandem radiation therapy
US6422989B1 (en) 1997-05-30 2002-07-23 Scimed Life Systems, Inc. Method for intravascular radioactive treatment
US20020099255A1 (en) * 1997-09-23 2002-07-25 Liprie Sam F. Afterloader apparatus
US6505392B1 (en) * 1994-06-08 2003-01-14 Interventional Therapies Llc Process for manufacturing a radioactive source wire for irradiating diseased tissue
US6508754B1 (en) 1997-09-23 2003-01-21 Interventional Therapies Source wire for radiation treatment
US6599230B2 (en) 1996-02-29 2003-07-29 Scimed Life Systems, Inc. Intravascular radiation delivery system
US6616629B1 (en) 1994-06-24 2003-09-09 Schneider (Europe) A.G. Medical appliance with centering balloon
US6676590B1 (en) * 1997-03-06 2004-01-13 Scimed Life Systems, Inc. Catheter system having tubular radiation source

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8221358B2 (en) 2007-11-20 2012-07-17 Warsaw Orthopedic, Inc. Devices and methods for delivering drug depots to a site beneath the skin

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1288048A (en) * 1917-03-21 1918-12-17 George Kunkle Radium-applicator.
US1867624A (en) * 1930-04-01 1932-07-19 Memorial Hospital For The Trea Device for obtaining biopsy specimens
US2546761A (en) * 1950-01-13 1951-03-27 Radium Chemical Company Inc Radium nasopharyngeal applicator
GB857992A (en) * 1959-07-25 1961-01-04 Willy Buesch Apparatus for the radio-active radiation treatment of the inner cavities of a body
US3480778A (en) * 1966-04-11 1969-11-25 Nuclear Chicago Corp Liquid scintillation sample standardization apparatus

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1288048A (en) * 1917-03-21 1918-12-17 George Kunkle Radium-applicator.
US1867624A (en) * 1930-04-01 1932-07-19 Memorial Hospital For The Trea Device for obtaining biopsy specimens
US2546761A (en) * 1950-01-13 1951-03-27 Radium Chemical Company Inc Radium nasopharyngeal applicator
GB857992A (en) * 1959-07-25 1961-01-04 Willy Buesch Apparatus for the radio-active radiation treatment of the inner cavities of a body
US3480778A (en) * 1966-04-11 1969-11-25 Nuclear Chicago Corp Liquid scintillation sample standardization apparatus

Cited By (50)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4086914A (en) * 1977-02-11 1978-05-02 Edwin Bailey Moore Implant injector
US4167179A (en) * 1977-10-17 1979-09-11 Mark Kirsch Planar radioactive seed implanter
US4627420A (en) * 1983-10-31 1986-12-09 Katz Harry R Needle inserting instrument for interstitial radiotherapy
US5141487A (en) * 1985-09-20 1992-08-25 Liprie Sam F Attachment of radioactive source and guidewire in a branchy therapy source wire
US4819618A (en) * 1986-08-18 1989-04-11 Liprie Sam F Iridium/platinum implant, method of encapsulation, and method of implantation
US5010892A (en) * 1988-05-04 1991-04-30 Triangle Research And Development Corp. Body lumen measuring instrument
US5575749A (en) * 1988-08-04 1996-11-19 Omnitron International, Inc. Ultra-thin high dose radioactive source wire
US5084002A (en) * 1988-08-04 1992-01-28 Omnitron International, Inc. Ultra-thin high dose iridium source for remote afterloader
US4976680A (en) * 1988-10-07 1990-12-11 Hayman Michael H Apparatus for in situ radiotherapy
US4957476A (en) * 1989-01-09 1990-09-18 University Of Pittsburgh Afterloading radioactive spiral implanter
US5199939A (en) * 1990-02-23 1993-04-06 Dake Michael D Radioactive catheter
US5213561A (en) * 1990-09-06 1993-05-25 Weinstein Joseph S Method and devices for preventing restenosis after angioplasty
US5092834A (en) * 1990-10-12 1992-03-03 Omnitron International, Inc. Apparatus and method for the remote handling of highly radioactive sources in the treatment of cancer
US6514191B1 (en) 1993-07-01 2003-02-04 Schneider (Europe) A.G. Medical appliances for the treatment of blood vessels by means of ionizing radiation
US6074338A (en) * 1993-07-01 2000-06-13 Schneider (Europe) A.G. Medical appliances for the treatment of blood vessels by means of ionizing radiation
US6071227A (en) * 1993-07-01 2000-06-06 Schneider (Europe) A.G. Medical appliances for the treatment of blood vessels by means of ionizing radiation
US6505392B1 (en) * 1994-06-08 2003-01-14 Interventional Therapies Llc Process for manufacturing a radioactive source wire for irradiating diseased tissue
US6876712B1 (en) 1994-06-08 2005-04-05 Interventional Therapies, L.L.C. Flexible source wire for localized internal irradiation of tissue
US5688220A (en) * 1994-06-10 1997-11-18 Schneider (Europe) A.G. Medical appliance for treatment by ionizing radiation
US6582352B2 (en) 1994-06-10 2003-06-24 Schneider (Europe) A.G. Medical appliance for treatment by ionizing radiation
US6231494B1 (en) 1994-06-10 2001-05-15 Schneider (Europe) A.G. Medical device with radiation source
US6616629B1 (en) 1994-06-24 2003-09-09 Schneider (Europe) A.G. Medical appliance with centering balloon
US5899882A (en) * 1994-10-27 1999-05-04 Novoste Corporation Catheter apparatus for radiation treatment of a desired area in the vascular system of a patient
US7066872B2 (en) 1994-10-27 2006-06-27 Best Vascular, Inc. Method and apparatus for treating a desired area in the vascular system of a patient
US6306074B1 (en) 1994-10-27 2001-10-23 Novoste Corporation Method and apparatus for radiation treatment of a desired area in the vascular system of a patient
US5683345A (en) * 1994-10-27 1997-11-04 Novoste Corporation Method and apparatus for treating a desired area in the vascular system of a patient
US7160238B1 (en) 1994-10-27 2007-01-09 Best Vascular, Inc. Method and apparatus for treating a desired area in the vascular system of a patient
US5728042A (en) * 1995-06-22 1998-03-17 Schneider (Europe) A.G. Medical appliance for ionizing radiation treatment having radiopaque markers
US6347443B2 (en) 1995-11-27 2002-02-19 International Brachytherapy S.A. Method of making a hollow-tube precursor brachytherapy device
US5713828A (en) * 1995-11-27 1998-02-03 International Brachytherapy S.A Hollow-tube brachytherapy device
US6163947A (en) * 1995-11-27 2000-12-26 International Brachytherapy S.A. Method of making a hollow-tube brachytherapy device
US6146322A (en) * 1995-12-05 2000-11-14 Schneider (Europe) Ag Irradiating filament and method of making same
US6398708B1 (en) 1996-02-29 2002-06-04 Scimed Life Systems, Inc. Perfusion balloon and radioactive wire delivery system
US6599230B2 (en) 1996-02-29 2003-07-29 Scimed Life Systems, Inc. Intravascular radiation delivery system
US6117065A (en) * 1997-03-06 2000-09-12 Scimed Life Systems, Inc. Perfusion balloon catheter with radioactive source
US6676590B1 (en) * 1997-03-06 2004-01-13 Scimed Life Systems, Inc. Catheter system having tubular radiation source
US6110097A (en) * 1997-03-06 2000-08-29 Scimed Life Systems, Inc. Perfusion balloon catheter with radioactive source
US6267775B1 (en) 1997-03-21 2001-07-31 Schneider (Usa) Inc. Self-expanding medical device for centering radioactive treatment sources in body vessels
US5938604A (en) * 1997-05-28 1999-08-17 Capintec, Inc. Radioactive needle for biopsy localization and a method for making the radioactive needle
US6422989B1 (en) 1997-05-30 2002-07-23 Scimed Life Systems, Inc. Method for intravascular radioactive treatment
US20020099255A1 (en) * 1997-09-23 2002-07-25 Liprie Sam F. Afterloader apparatus
US6508754B1 (en) 1997-09-23 2003-01-21 Interventional Therapies Source wire for radiation treatment
US6258019B1 (en) 1997-09-26 2001-07-10 Scimed Life Systems, Inc. Catheter for intraluminal treatment of a vessel segment with ionizing radiation
US6264596B1 (en) 1997-11-03 2001-07-24 Meadox Medicals, Inc. In-situ radioactive medical device
US6175760B1 (en) * 1998-02-17 2001-01-16 University Of Iowa Research Foundation Lesion localizer for nuclear medicine
US6352501B1 (en) 1999-09-23 2002-03-05 Scimed Life Systems, Inc. Adjustable radiation source
US6203485B1 (en) 1999-10-07 2001-03-20 Scimed Life Systems, Inc. Low attenuation guide wire for intravascular radiation delivery
US6398709B1 (en) 1999-10-19 2002-06-04 Scimed Life Systems, Inc. Elongated member for intravascular delivery of radiation
US6416457B1 (en) 2000-03-09 2002-07-09 Scimed Life Systems, Inc. System and method for intravascular ionizing tandem radiation therapy
US6302865B1 (en) 2000-03-13 2001-10-16 Scimed Life Systems, Inc. Intravascular guidewire with perfusion lumen

Also Published As

Publication number Publication date Type
FR2007684A1 (en) 1970-01-09 application
GB1239493A (en) 1971-07-14 application

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