US3627775A - 1-alkyl-1,2,5,6-tetrahydro-3-pyridylmethyl carboxylic - Google Patents

1-alkyl-1,2,5,6-tetrahydro-3-pyridylmethyl carboxylic Download PDF

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Publication number
US3627775A
US3627775A US836658A US3627775DA US3627775A US 3627775 A US3627775 A US 3627775A US 836658 A US836658 A US 836658A US 3627775D A US3627775D A US 3627775DA US 3627775 A US3627775 A US 3627775A
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US
United States
Prior art keywords
tetrahydro
pyridylmethyl
carbon atoms
alkyl
acid ester
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
US836658A
Other languages
English (en)
Inventor
Hans-Hugo Hubner
Gerhard Walther
Karl Zeile
Helmut Wick
Klaus Stockhaus
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CH Boehringer Sohn AG and Co KG
Boehringer Ingelheim GmbH
Original Assignee
CH Boehringer Sohn AG and Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CH Boehringer Sohn AG and Co KG filed Critical CH Boehringer Sohn AG and Co KG
Application granted granted Critical
Publication of US3627775A publication Critical patent/US3627775A/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms

Definitions

  • R is phenyl, cyclopentyl or cyclohexyl

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
US836658A 1968-06-25 1969-06-25 1-alkyl-1,2,5,6-tetrahydro-3-pyridylmethyl carboxylic Expired - Lifetime US3627775A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT609868A AT287711B (de) 1968-06-25 1968-06-25 Verfahren zur Herstellung von neuen 1-Alkyl-1,2,5,6-tetrahydro-3-pyridylmethyl-carbonsäureestern sowie deren Säureadditionssalzen und quaternären Ammoniumverbindungen

Publications (1)

Publication Number Publication Date
US3627775A true US3627775A (en) 1971-12-14

Family

ID=3582843

Family Applications (1)

Application Number Title Priority Date Filing Date
US836658A Expired - Lifetime US3627775A (en) 1968-06-25 1969-06-25 1-alkyl-1,2,5,6-tetrahydro-3-pyridylmethyl carboxylic

Country Status (11)

Country Link
US (1) US3627775A (pt)
AT (1) AT287711B (pt)
BE (1) BE735141A (pt)
BR (1) BR6910094D0 (pt)
CH (1) CH513164A (pt)
DE (1) DE1929921A1 (pt)
ES (3) ES368698A1 (pt)
FR (1) FR2014218A1 (pt)
GB (1) GB1257960A (pt)
IL (1) IL32469A0 (pt)
NL (1) NL6909425A (pt)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4467095A (en) * 1969-02-10 1984-08-21 Fmc Corporation Anticholinergic compounds
US4472408A (en) * 1981-03-11 1984-09-18 Sanofi Substituted trifluoromethylphenyltetrahydropyridines having an anorectic activity

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2043455A1 (de) * 1970-09-02 1972-03-09 CH. Boehringer Sohn, 6507 Ingelheim Neue l,2,3,6-tetrahydro-4-pyridylmethyl-carbonsäureester, sowie deren Säureadditionssalze und quarternären Ammoniumverbindungen
US3879556A (en) * 1970-09-02 1975-04-22 Boehringer Sohn Ingelheim Pharmaceutical compositions containing a 1,2,3,6-tetrahydro-4-pyridylmethyl carboxylate and method of use
DE3801659A1 (de) * 1988-01-21 1989-07-27 Boehringer Ingelheim Kg Tetrahydropyridin - derivate

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2607777A (en) * 1947-04-10 1952-08-19 Searle & Co N-alkyl piperidyl alkyl esters of diphenyl acetic acid and 9-fluorenyl carboxylic acid
GB886437A (en) * 1959-07-15 1962-01-10 Beecham Res Lab Improvements in or relating to basic esters of etherified benzilic acids

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
Benington et al., J. Org. Chem., Vol. 25, No. 11, pp. 1,912 1,916, 1960 QD241J.6 *
Burger, Medicinal Chemistry, Second Edition, Interscience, pp. 497, 1960 RS 403 B 8 1960 C.7 *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4467095A (en) * 1969-02-10 1984-08-21 Fmc Corporation Anticholinergic compounds
US4472408A (en) * 1981-03-11 1984-09-18 Sanofi Substituted trifluoromethylphenyltetrahydropyridines having an anorectic activity
US4602024A (en) * 1981-03-11 1986-07-22 Sanofi Substituted trifluoromethylphenyltetrahydropyridines having a cyano substituent and an anorectic activity, a process for preparing same and pharmaceutical compositions

Also Published As

Publication number Publication date
DE1929921A1 (de) 1970-01-02
ES368698A1 (es) 1971-07-01
ES374407A1 (es) 1972-01-01
FR2014218A1 (pt) 1970-04-17
IL32469A0 (en) 1969-08-27
BR6910094D0 (pt) 1973-04-05
NL6909425A (pt) 1969-12-30
CH513164A (de) 1971-09-30
GB1257960A (pt) 1971-12-22
BE735141A (pt) 1969-12-29
ES374408A1 (es) 1972-01-01
AT287711B (de) 1971-02-10

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