US3578039A - Automatic proportioner assembly - Google Patents

Automatic proportioner assembly Download PDF

Info

Publication number
US3578039A
US3578039A US767676A US3578039DA US3578039A US 3578039 A US3578039 A US 3578039A US 767676 A US767676 A US 767676A US 3578039D A US3578039D A US 3578039DA US 3578039 A US3578039 A US 3578039A
Authority
US
United States
Prior art keywords
fitting
syringe
fluid
receptacle
liquid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
US767676A
Other languages
English (en)
Inventor
Edward P Marbach
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cooper Laboratories Inc
Original Assignee
Baxter Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baxter Laboratories Inc filed Critical Baxter Laboratories Inc
Application granted granted Critical
Publication of US3578039A publication Critical patent/US3578039A/en
Assigned to COOPER LABORATORES, INC. reassignment COOPER LABORATORES, INC. ASSIGNMENT OF ASSIGNORS INTEREST. Assignors: BAXTER TRAVENOL LABORATORIES, INC., A CORP. OF DE
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Images

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/56—General build-up of the mixers

Definitions

  • proportioning devices in many cases include a syringe having a plunger and a relatively movable telescopic barrel member with a liquid conduit connected thereto for withdrawing and delivering both reagent and sample.
  • a proportioning device is disclosed in the Marbach et al. Pat. No. 3,236,423 and reference should be made thereto for a more complete description of such a device.
  • syringe devices of this character have been automated by providing fluid. actuators for driving the barrel portion of the syringe and selectively operable valves for connecting the syringe to either a source of reagent or a sample source through a sample pipet connected to the valve.
  • a suitable control system for connecting the syringe to a source of reagent and driving the barrel to draw reagent into the syringe. After a predetermined amount of reagent is drawn into the syringe the valve is switched to the sample pipet and the actuator continues its movement drawing in a predetermined quantity of sample. Thereafter, the actuator is reversed and the sample and reagent discharged into another receptacle.
  • an integrated reagent receptacle and valve assembly is provided which is easily removable from the main proportioner housing along with the syringe itself. This is particularly desirable in units where the syringes are precalibrated so that if a different dilution ratio is required, a different syringe must be employed.
  • the syringe and subassembly may be removed and replaced by another syringe and subassembly without any danger of cross contamination between the two subassemblies.
  • FIG. 3 is an enlarged fragmentary section of one of the releasable fittings.
  • an automatic proportioner 10 which is seen to include a housingll having a boss 12 which supports a syringe 14.
  • a clamp 15 is provided for locking the syringe 14 in position.
  • the syringe 14 includes a base 16 having a plunger 18 extending upwardly therefrom. Telescopically received on the plunger 18 is a barrel 20 having a fitting 21 on the upper end thereof releasably connected to a main syringe liquid conduit 24.
  • the main liquid conduit 24 is selectively connected to a sample conduit 28 or a reagent conduit 29 by a two position valve 31 which may take the form of a diaphragm operated spool valve although other types of valves may be used as well.
  • the valve 31 is constructed to connect liquid port 32 to either sample port 33 or reagent port 34.
  • the valve is shifted from one position to another by the selective application of fluid underpressure to ports 36 at both ends of the valve.
  • This fluid might be a liquid or it might be a gas, such as air.
  • an actuator for reciprocating the barrel 20-as well as a control system for controlling movementof the actuator and providing fluid signals, e.g.- air, to the passages 40 the conduits 28 or 29 to the other is desired.
  • the control system is operable to provide a fluid signal in conduit or passageway 40 when it is desired that a fluid signal be ported to shift the valve member to a position connecting liquid conduit 24 to the sample conduit 28, and is operable to deliver a signal through conduit or passageway 41 when it is 'desired that the valve 31 connect conduit 24 to reagent con-.
  • the main proportioner housing 11 is provided with a horizontally extending flange 42 at its upper end having a shoulder 43 extending upwardly therefrom and defining a surface 44 which receives a main housing cap 46. Both the cap 46 and the flange 42 have recesses 48 and 49 therein through which the flexible liquid conduit 24 may freely pass.
  • fittings 37 and 38 Seated within the flange 42 are fittings 37 and 38 of identical construction-These fittings each include a generally annular'flange member 47 with a sealing O-ring 39 mounted within an annular recess in the fittings. Each fitting has a central passageway 50 communicating with a barbed fitting 52 projecting downwardly from the flange 42.
  • The'conduits 40 and 41 are continuously connected to the barb fittings 52and do not require removal with the valve 31 or thesyringe 14 as will appear more clearly hereinbelow.
  • a unitary valve and reagent'subassembly 60 is provided.
  • the subassembly 60 is very easily and releasably attached to the main housing 11 and may be removed with all the liquid conduits associated with the device including the main liquid conduit or passageway 24.
  • the subassembly 60 includes a generally cylindrical reagent reservoir 61 having a neck portion 63 formed integrally with an L-shaped bracket member 65 having a flange portion "68 extending outwardly from the subassembly and having a lower surface 72 selectively engageable with the'upper surface of flange 42. Molded in the flange 68 are hollow metal sleevesi74 and 75, the interiors of which communicate with transverse passageways 78 in .the flange 68, each of which receives a pipelike fitting member 79. The fittings 79 receive flexible conduits 81 and 82 connected to the ports 36 for actuating the valve diaphragms in the manner described above.
  • Cap 83 Surrounding the L-shaped bracket 65-and the flange 68 is a cup-shaped cap 83 having a projecting portion 85 surrounding the flange 68.
  • Cap 83 has a suitable supporting'boss (not shown) for supporting the valve member 31 within the cap.
  • the sample conduit v28 extends from the valve port 34 througha suitable aperture 88 in the L-shaped bracket 65 .and has a pipet 90 at its end for receiving sample liquid.
  • the reagent conduit 29 extends from valve port 34 within the cap through aperture 92 in bracket 65 down into the interior of the receptacle 61.
  • valve and reagent subassembly 60 When it is desired that the subassembly 60 be removed and replaced by another valve and reagent subassembly, it is merely necessary to remove the main liquid line from the fitting 21 on the barrel member and lift the bracket 65 upwardly removing the sleeves 74 and 75 from the fittings 37 and 38. This disconnects the liquid conduit from the syringe 14 as well as disconnects the valve actuating signal lines 40 and 41 from the valve actuating lines 81 and 82, respectively, Another valve and reagent subassembly may be attached to the main housing 11 by inserting its sleeves 74 and 75 in the fittings 37 and 38.
  • the sealing rings 39 seal the sleeves 74 and 75 and provide an airtight fluid passage from conduits 40 and 41 through passages 78 to conduits 81 and 82.
  • the syringe 14 may be unclamped and the conduit 24 and the subassembly 60 may all be removed at the same time quickly and another set of these elements with a different syringe calibration, and even a different reagent, attached quite easily.
  • an automatic proportioner of the type having a calibrated syringe and fluid controls for providing fluid signals when switching from one fluid to another comprising: a main proportioner housing, a syringe mounted in said housing for withdrawing and delivering liquids, fluid control components in said main housing for providing fluid signals when it is desired to connect said syringe from one liquid to another, first fluid fitting means in said main housing continuously connected to said control components, liquid receptacle means separate from said main housing for containing one of said liquids, valve means connected to said liquid receptacle for selectively connecting said syringe to the liquid in the receptacle or another liquid, liquid conduit means adapted to connect said valve means and said syringe, second fluid fitting means fixed to said receptacle means, and conduit means connecting said fluid fitting means to actuate said valve means, said first and second fluid fitting means being releasably connectable whereby the receptacle means may be removed with the liquid conduits from the main housing.
  • one of said fitting means includes a sleeve member insertable within the other of said fitting means to fix the receptacle to LII said main housing and to also provide a conduit for the fluid signal to actuate said valve means.
  • said receptacle means includes a container for said first liquid, a flange member projecting outwardly from the top of the container, said second fitting being mounted in said flange member.
  • valve means includes a first liquid conduit extending downwardly into said container and a second liquid conduit for communication with another liquid.
  • an automatic proportioner comprising: main housing means, a syringe connected in said main housing means, and adapted to proportion first and second liquids, control means for said syringe and for providing a fluid signal when it is desired to switch from the first to the second liquids, first fitting means in said main housing, conduit means continuously connecting said control means to deliver said fluid signal to said first fitting means, second housing means separate from said main housing means and releasably connected thereto, said second housing having valve means fixed thereto and adapted to connect said syringe selectively tonne of said first and second liquids, second fitting means in said second housing for receiving said fluid signal, said first and second fitting means being releasably connected, and conduit means connecting said second fitting means to deliver said fluid signal to said valve means.

Landscapes

  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Devices For Use In Laboratory Experiments (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
US767676A 1968-10-15 1968-10-15 Automatic proportioner assembly Expired - Lifetime US3578039A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US76767668A 1968-10-15 1968-10-15

Publications (1)

Publication Number Publication Date
US3578039A true US3578039A (en) 1971-05-11

Family

ID=25080217

Family Applications (1)

Application Number Title Priority Date Filing Date
US767676A Expired - Lifetime US3578039A (en) 1968-10-15 1968-10-15 Automatic proportioner assembly

Country Status (6)

Country Link
US (1) US3578039A (enExample)
JP (1) JPS5020871B1 (enExample)
BE (1) BE740173A (enExample)
DE (1) DE1950844A1 (enExample)
FR (1) FR2020709A1 (enExample)
GB (1) GB1231355A (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090035873A1 (en) * 2007-07-31 2009-02-05 Sysmex Corporation Sample analyzer, sample analyzing method, and computer program product
CN106115005A (zh) * 2016-08-18 2016-11-16 无锡市稼宝药业有限公司 一种便于拆卸的农药生产用液体分装机

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3676928B2 (ja) 1998-08-11 2005-07-27 株式会社マキタ バイス装置のフェンス
CN115090181B (zh) * 2022-07-21 2024-01-02 上海大学 一种高精度铟金属电解液自动配比装置及方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3349815A (en) * 1963-05-09 1967-10-31 Baets Jozef Maurits De Proportioning installation

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3349815A (en) * 1963-05-09 1967-10-31 Baets Jozef Maurits De Proportioning installation

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090035873A1 (en) * 2007-07-31 2009-02-05 Sysmex Corporation Sample analyzer, sample analyzing method, and computer program product
US8158439B2 (en) * 2007-07-31 2012-04-17 Sysmex Corporation Multiple operating mode sample analyzer, analyzing method, and computer program product
CN106115005A (zh) * 2016-08-18 2016-11-16 无锡市稼宝药业有限公司 一种便于拆卸的农药生产用液体分装机

Also Published As

Publication number Publication date
DE1950844A1 (de) 1970-04-16
FR2020709A1 (enExample) 1970-07-17
GB1231355A (enExample) 1971-05-12
BE740173A (enExample) 1970-03-16
JPS5020871B1 (enExample) 1975-07-18

Similar Documents

Publication Publication Date Title
US3869068A (en) Diluter probe assembly
US5474744A (en) Automatic pipetting device with cleaning mechanism
US5679575A (en) Particle measuring apparatus and method
EP0135985A2 (en) Dispenser apparatus
US3012863A (en) Apparatus for the preparation of laboratory test samples
US4503012A (en) Reagent dispensing system
US3310002A (en) Pipette pump
US4793524A (en) Integrated reagent container and metered dispenser means
EP0121127A1 (en) Liquid chromatography proportioning valve and mixer
US4332768A (en) Arrangement for supplying metered quantities of reagent liquid to the test tubes of an analyzing apparatus
US3578039A (en) Automatic proportioner assembly
US3757421A (en) Valve and system for dental apparatus
JP5339906B2 (ja) ２エダクター／４方向選択弁組立体
EP0078828B1 (en) Apparatus for sampling of liquid
US3807562A (en) Check valve and filter assembly
US3860347A (en) Cuvette construction
US6810923B2 (en) Pipet for liquid exchange
GB2234065A (en) Sampling liquids.
US6131601A (en) Fluid mixing apparatus
US4621060A (en) Apparatus for taking samples from a fermenter
FI80147B (fi) Foerfarande foer foerverkligande av val av vaetska vid vaetskedosering i en analysator samt provtagningsanordning.
US2713268A (en) Liquid sampler
US7367243B1 (en) Traps and vents in flow-through pipet
JP2019086426A (ja) 分注装置、分注装置の制御方法、生化学分析装置
US5607080A (en) Chemical measuring system

Legal Events

Date Code Title Description
AS Assignment

Owner name: COOPER LABORATORES, INC., 3145 PORTER DRIVE, PALO

Free format text: ASSIGNMENT OF ASSIGNORS INTEREST.;ASSIGNOR:BAXTER TRAVENOL LABORATORIES, INC., A CORP. OF DE;REEL/FRAME:004067/0785

Effective date: 19820917