US3576206A - Isolation entryway assembly - Google Patents

Abstract

This invention relates to a novel method and means for enabling a person to leave an isolator room while preventing contaminants from entering the area or room. More particularly, this invention relates to an isolator structure having a sterile locker or anteroom with a pair of entrances which are sealed by troughs or reservoirs of fluid.

Description

States Patent Inventor Philip C. Trexler Stoneham, Mass. App]. No. 840,896 Filed June 13, 1969 Division of Ser. No. 639,669, May 19, 1967, Pat. No. 3,501,213 Patented Apr. 27, 1971 Assignee Snyder Manufacturing Company, Inc.

New Philadelphia, Ohio ISOLATION ENTRYWAY ASSEMBLY 5 Claims, 10 Drawing Figs.

US. Cl 160/84, 312/1 Int. Cl E06b 3/94 Field of Search 160/84; 128/1; 312/1 [56] References Cited UNITED STATES PATENTS 1,663,819 3/1928 Shaft 160/84 2,600,240 6/1952 Grieb 3 l 2/1X 2,842,773 7/1958 Trexler'. 3 l 2/1X 3,355,230 11/1967 Trexler 128/1X 3,439,966 4/1969 Perkins et al. 128/1X Primary Examiner-Peter M. Caun Att0rney-Olson, Trexler, Wolters & Bushnell ABSTRACT: This invention relates to a novel method and means for enabling a person to leave an isolator room while preventing contaminants from entering the area or room. More particularly, this invention relates to an isolator structure having a sterile locker or anteroom with a pair of entrances which are sealed by troughs or reservoirs of fluid.

PATENTED APR27 I971 sum 1 BF 4 PATENTEU APR27197:

SHEET it UP 4 III III 11/ 11/,

ISULA'IION YWAY ASSEMBLY Reference to the Related Application This application is a division of the U.S. Pat. application Ser. No. 639,669, filed May 19, 1967 now U.S. Pat. No. 3,501,213.

In 1895 the first vertebrate was reared in an environment which was free from microbic contamination. Since then studies have been made wherein colonies of animals have been raised in an uncontaminated environment. Most of these studies are conducted in rigidwalled chambers or specimen rooms having a carefully controlled environment. Entering and leaving of these specimen rooms must be done with great care to ensure that contaminants do not enter the specimen rooms.

Entry and exit from the controlled environment of specimen rooms is commonly accomplished by means of a sterilizing or decontaminating locker which is connected to the specimen room. The locker usually has a first opening leading to a normal or uncontrolled surrounding environment and a second entrance leading to the controlled environment of the specimen room. These entrances usually include door structures which are sealed to prevent contaminants from entering the specimen room through the locker.

When a person desires to enter the specimen room, he must first put on a protective fluidtight garment, similar to a diving suit, having a hose connected to a source of air. The person then enters the locker through the first entrance while the second entrance is sealed. A length of airhose sufficient to enable the person to move freely about the specimen room is pulled into the locker. The first entrance is then sealed, and the locker, the protective suit and the airhose are sterilized. After the sterilizing of the locker, the second entrance is opened and the person enters the controlled environment of the specimen room. Upon leaving the specimen room, the above process of entry to and from the locker is reversed.

The first and second locker entrances should provide secure seals which do not allow contaminants to enter the specimen room. At the same time, the entrances should be readily operated to enable a person wearing a cumbersome protective suit with a trailing airhose to enter and leave the specimen room. The paramount necessity of obtaining a secure seal at the locker entrances has resulted in the use in prior art lockers of closure structures or doors which are difficult and time consuming to manipulate. The difi'iculties in operating prior art locker closures or doors become quite onerous for a person encased in a cumbersome protective garment. This is particularly true since the wearer of the protective garment must be extremely careful not to puncture the garment while operating the closures or doors.

Therefore, it is an object of this invention to provide an improved locker structure for an isolator assembly which overcomes the aforementioned limitations of prior art constructions. Specifically, it is an object of this invention to provide an improved locker closure structure or door which is easily operated and provides a secure seal against the passage of contaminants when the closure structure or door is sealed.

Another object of this invention is to provide a closure or door structure for a locker through which an airhose can be pulled and sterilized when the closure or door is sealed.

Another object of this invention is to provide an inexpensive easily operated closure or door which is positively sealed by a trough or reservoir of fluid positioned adjacent to the closure or door.

Another object of this invention is to provide a locker structure which can be used with a plurality of flexible-walled specimen rooms.

These and other objects and features of the invention will become more apparent upon a reading of the following detailed description taken in connection with the accompanying drawings wherein:

FIG. I is a sectional view illustrating an isolator assembly including a specimen room connected to a locker or anteroom, the anteroom including a pair of entryways which are shown in a sealed position;

FIG. 2 is a sectional view, similar to FIG. 1, illustrating the isolator assembly with an entrance between the surrounding environment and the anteroom in an open position to enable a person clad in a protective garment to enter the anteroom;

FIG. 3 is an enlarged sectional view of the anteroom of FIG. 1 with the entryways in a closed or sealed position while the protective garment and the anteroom are being sterilized or decontaminated by a germicidal spray or sterilizing medium;

FIG. 4 is a sectional view, similar to FIGS. 1 and 2, illustrating the anteroom with the entryway between the anteroom and the surrounding environment sealed and the entryway between the anteroom and the specimen room open to enable the person to enter the specimen room from the anteroom;

FIG. 5 is a sectional view, similar to FIG. 4, illustrating the person in the specimen room;

FIG. 6 is an enlarged fragmentary perspective view of a closure assembly used in the anteroom entryways of FIGS. 1 through 5, the closure assembly being shown in a sealed or closed position;

FIG. 7 is an enlarged perspective view illustrating the closure assembly of FIG. 6 in an unsealed or open position;

FIG. 8 is an enlarged sectional view, taken along the line of FIG. 7, further illustrating the closure assembly of FIG. 6 in the open position;

FIG. 9 is an enlarged perspective view illustrating eyelets or guide tabs and a drive cable which provide an interconnection between the drive assembly and the closure assembly of FIG. 6; and

FIG. 10 is an enlarged elevational view of a drive motor used for operating the closure assembly of FIG. 6.

Referring to the drawings in greater detail, an isolator assembly 20 is shown in FIG. 1. The isolator assembly 20 includes a specimen room or chamber 22 having a plurality of flexible walls 24 formed from a film of vinyl material, such as high density polethylene, polypropylene, tetrafluoroethylene polymer, trifluorochloroethylene polymer, polyethylene terephthalate resin, or other flexible vinyl'resin films. The flexible walls 24 are supported by a frame 26 which is connected to the walls 24 by a suitable support structure 30. A specimen chamber or container 32 is advantageously provided within the specimen room for holding; specimens which are to be maintained in a controlled environment. The environment in the specimen rooms 22 is controlled in a known manner by means of an air supply conduit having a filter and an exhaust conduit (not shown).

An anteroom or decontamination locker or chamber 36 is connected to the specimen room 22 by a releasable connector assembly 38. The anteroom 36 has a plurality of rigid metallic walls 40 which support an air outlet assembly 42. The air outlet assembly 42 is connected to a scrubbing tower or filter d4 of known construction having a fan to maintain a slight negative pressure within the anteroom 36. The anteroom 36 also includes a pair of outwardly extending flanges or mounting walls 48 and 50 which define apertures or entryways 52 and 54 in opposite walls 40 of the anteroom 36. Closure assemblies or door structures 56 and 58 are mounted on the flanges 48 and 50 to form a selectively scalable passage for entering and leaving the anteroom 36. The doors 56 and 58 are shown in a closed or sealed position in which inner end portions or sections 60 and 62 are partially immersed in a pair of spaced-apart troughs or channels 64 and 66 forming reservoirs of a volatile germicidal or sterilizing fluid such as a peracetic acid or strong chlorine solution. The air outlet or exhaust system 42 and scrubbing tower 44 remove irritating and corrosive fumes which are given off by the reservoirs of volatile germicidal solution.

A person, such as a worker, is illustrated at 70 in FIG. 1. The worker is encased or enclosed in a protective garment 72 having an airhose 74. The protective garment 72 is advantageously constructed in a manner set forth in detail in U.S. Pat. No. 2,779,331. The protective garment 72 prevents contaminants from passing outwardly from the body of the worker and, also, prevents contaminants from passing inwardly to the worker.

The worker 76 enters the anteroom 36 through the entryway closure assembly or door structure 58 which is shown in an open position in FIG. 2. It should be noted that the closure assembly 66 is in a closed or sealed position while the closure assembly 52; is open, so that contaminants from the uncontrolled or normal surrounding environment, indicated at 80 in FIG. 2, cannot enter the specimen room 22 through the entryway between the specimen room and the anteroom. Once the worker has entered the anteroom 36, he operates the closure assembly 58 to seal the entryway 54 between the anteroom and the surrounding environment by positioning the end portion 62 of the closure assembly in the reservoir 66 of fluid, as shown in FIG. 3. The anteroom 36, the protective garment 72, and the airhose '74 are then sterilized by germicidal sprays from a pair of spray heads or fixtures 84 and 86. The worker 70 uses a hand spray gun 88, of known construction, to spray a sterilizing or germicidal medium onto any folds or creases in the closure assemblies 56 and 58 to insure neutralization of all contaminants within the anteroom 36.

After the anteroom 36 has been decontaminated, the worker 70 enters the specimen room 22 by opening the closure assembly 56, as illustrated in FIG. 4. While the closure assembly 56 is open, the closure assembly 56 is maintained in the closed position to seal the entryway between the anteroom 36 and the exterior surrounding environment 80. Since the anteroom has been decontaminated, contaminants or foreign bodies are effectively sealed out of the specimen room 22 while the worker 76 is in the specimen room.

Once inside the specimen room 22, the worker 70 can manipulate and otherwise conduct experiments on animals or specimens within the container 32, as shown in FIG. 5. If a second worker is to join the first worker in the specimen room 22, the closure assembly 56 is closed, as shown in FIG. I, with the first workers airhose 74 extending into and out of the reservoir 6 through the closure assembly 56. The second worker then opens the closure assembly 58, enters the anteroom, closes the closure assembly 58 to seal the entrance between the anteroom and the surrounding environment, and decontaminates the anteroom, as shown in FIG. 3. The second worker then reopens the closure assembly 56 and joins the fust worker in the specimen room 22. This relatively free access to the specimen room is made possible by the closure assemblies 56 and 553 which are easy to operate and provide a seal around the airhoses of the workers.

Of course, the two workers leave the specimen room 22 by reversing the procedure previously set forth. Thus, the workers enter the anteroom 36 from the specimen room 22 through the entryway 52, seal the entryway by positioning the closure assembly 56, as shown in FIG. 3, with the inner end portion 60 in the reservoir 64 to seal the entryway against the passage of contaminants into the specimen room. If the specimen room contained organisms which would be harmful or otherwise undesirable in the surrounding environment 80, the anteroom 36 and the protective garments 72 of the workers would be decontaminated or sterilized, as shown in FIG. 3. However, if the specimen room 22 did not contain dangerous or harmful organisms, the decontamination step of FIG. 3 could be eliminated upon leaving the specimen room 22. The workers then leave the anteroom 36 by moving the closure assembly 58 to the open position shown in FIG. 2 and stepping out of the anteroom.

Referring now to FIG. 6, the closure assembly 58 includes an outer portion 90 which extends through the entryway or aperture 56 and around the flange or the mounting wall 50, as shown in FIG. 8, where it is engaged by a plurality of resilient clamping bands 92 of synthetic rubber or other elastomeric material. The bands 92 form a releasable connector assembly to seal the end portion 96 of the closure assembly 58 against the flange 50. The closure assembly 58 is shown in the closed position in FIG. 6 with the inner end portion 62 of the closure assembly positioned within the reservoir 66 where it is blocked or sealed by the liquid in the reservoir. It should be noted that the closure assembly 58 includes an upper panel or mtion 96 which extends outwardly from an upper, generally horizontally extending edge 98 of the entryway 56. Similarly, a lower panel or section I60 (see FIG. 8) extends outwardly from a lower edge 102 of the entryway 54. The upper and lower panels 96 and are interconnected by a pair of side panels 104 and 106 which are folded and extend downwardly and inwardly in the closed position of FIG. 6. When in this position, the side panels 104 and 106 provide fold lines 103 and 105, respectively, which are disposed as shown in FIG. 6. The upper and lower panels 96 and 100 are of different lengths, as illustrated, the upper panel 96 being the longer of the two. The respective panels 96, 100, 104 and 106 are sized to provide an opening in the end portion 62 of the closure assembly 58 which is substantially the same size as the entryway 54. Thus, during opening, which is illustrated in FIG. 7, the side panels 104 and 106 are gathered about the longitudinal side edges I08 and 110 of said entryway while the upper and lower panels 96 and 100 are disposed approximate the horizontal edges of said entryway. The panels or sections 96, 100, 104 and 106 form a flexible generally tubular member I 16 having a central passage or entryway indicated at 118 in FIG. 7.

As is clearly seen from FIG. 7, the' passage 118 is substantially unimpeded when the flexible tubular member 114 is in the open position to enable a worker to move through the passage into the anteroom 36. When the closure assembly 58 is in the closed position of FIG. 6, with the end portion 62 immersed in the reservoir 66, the passage 118 is blocked or sealed by the fluid in the reservoir to prevent contaminants from passing between the surrounding environment 80 and the anteroom 36. A pair of bars or rods 122 and 124 are mounted in the end portion 62 of the closure assembly 56 to hold the end portion 62 in the position shown in FIG. 6.

As is best seen in FIG. 3, the closure assemblies 56 and 58 are substantially identical in construction and method of operation. Both the closure assemblies 56 and 58 are moved from the closed position shown in FIGS. 3 and 6 to the open position shown in FIGS. 7 and 8 by a pair of drive motors and 132 which are supported by an upper wall 40 of the anteroom 36. When the drive motor 132 is energized, a cable drum or spool 13% is rotated to wind up a drive cable 136. The winding up of the cable 136 lifts the bars 122 upwardly from the closed position shown in FIG. 6 to the open position shown in FIG. 8 by pulling the cable through a plurality of pulleys M0. When the direction of rotation of the motor 132 is reversed by a suitable switch means, the bar 122 is returned from the open position of FIG. 3 to the closed position of FIG. 6. In a similar manner, the drive motor 130 rotates a cable drum or spool 142 to move the closure assembly 56 from the closed position to the open position and back again.

As is perhaps best seen in FIGS. 6 and 9, the cable 136 extends through a plurality of eyelets or guide loops 146 to guide the movement of the cable 136 when the closure assemblies 56 and 58 are opened and closed. It has been found to be advantageous to provide control switches both within the anteroom 36 and exteriorly of the anteroom. The two control switch assemblies enable both the worker 70 within the anteroom 36 and assistants outside the anteroom 36 to move the closures 56 and 58 from theclosed position to the open position.

Referring now to FIG. 10, the motor 132 is advantageously provided with a seal 150 which includes a pair of spacedapart, substantially parallel annular walls 152 and 154 mounted on the rigid upper wall 40 of the anteroom 36. The annular walls 152 and 154 and the upper wall 40 define a reservoir 156 for sealing fluid I58. An annular outer wall 160 is connected to a base section 162 which is fixedly mounted on a shaft I64 of the motor 132 and is positioned intermediate the annular reservoir walls 152 and 154. Thus, the fluid 158 within the reservoir 156 seals an aperture 168 in the wall 40 through which the motor drive shaft 164 extends. A similar sealing structure 170 is used with the motor 130.

When the worker 70 is within the anteroom 36 and the closure assembly 58 is sealed by placing the inner end portion 62 in the reservoir 66, the airhose 76 extends through the passage 1113 which is sealed by the fluid within the reservoir 66 (see FIG. 3). After the worker has decontaminated the anteroom 36, in the manner illustrated in FIG. 3, he enters the specimen room 22, as shown in FIG. 4. In moving from the anteroom 36 to the specimen room 22, additional airhose must be pulled in the direction of the arrow ll'i l through the passage 1113 into the anteroom 36 to provide the necessary length or slack to enable the worker to move between the two rooms. Since the reservoir 66 is filled with a sterilizing or germicidal solution, the additional length of airhose is sterilized as it is pulled into the anteroom 36 by passing into and out of the reservoir 66. As is perhaps best seen in FIG. 3, the airhose is guided in this movement into the anteroom 36 by a plurality of pulleys or sheaves 176 and H78. Thus, since the airhose 76 is sterilized as it is pulled through the passage lie of the sealed entryway, the pulling of additional hose into the anteroom 36 and the specimen room 22 does not bring contaminants from the surrounding environment into the anteroom and the specimen room.

As was previously mentioned, the specimen room 22 has flexible walls 24 which are connected to an outwardly extending mounting wall 63 by a connector assembly 33 (see FIG. 3). The connector assembly 33 includes a plurality of resilient bands 132 which clamp the flexible wall 24 of the specimen room and the closure assembly 56 against the flange 48. The connector assembly 38 is readily released, by merely moving the bands 132 outwardly away from the flange 43 so that the specimen room 22 can be disconnected from the anteroom 36 and a new specimen room connected to the anteroom. This releasable connection between the anteroom 36 and the specimen room 22 enables the solid, relatively expensive anteroom 36 to be used with a plurality of flexible walled specimen rooms 22. Thus, at the end of one experiment, it is merely necessary to disconnect the specimen room 22 associated with that experiment from the anteroom 36 and connect a new specimen room 22, which can have any desired shape, to the anteroom for the next experiment.

After being attached to the anteroom 36, the new specimen room 22 is sterilized for the new experiment by using a spray gun, similar to the spray gun 33, to neutralize any contaminants which may be within the specimen room 22. The closure assembly 56 is not connected during the disinfecting or decontamination of the specimen room 22, so that surfaces which are concealed by the closure assembly 56 can be sterilized. The sterilized closure assembly 56 is then connected to the mounting wall or flange 43 and the worker steps into the sterilized anteroom 36 and closes the closure assembly 56. The closure assembly 58 is then opened and the worker leaves the anteroom 36. The specimen room 22 and anteroom 36 are now ready to begin the next experiment.

For purposes of affording a more complete understanding of the invention, it is advantageous now to provide a functional description of the mode in which the isolator assembly 26 operates. When an experiment is to be conducted, the specimen room 22 will be connected to the anteroom 36 at the outwardly extending flange 63 by connector bands W2. A worker will enter the anteroom 36, seal the closure assembly 53 and sterilize or decontaminate the anteroom and his protective garment 72. The worker will then proceed to sterilize the specimen room 22. After the specimen room 22 has been thoroughly sterilized, the closure assembly 56 will be connected to the flange 66 and the worker will enter the anteroom 36 and close the closure assembly 56. The closure assembly 56 will be sealed by liquid in the reservoir 64. The closure assembly 53 will then be opened and the worker will leave the anteroom 36.

Experimental specimens in a suitable container 32 will then be brought into the anteroom 36. The closure assembly 38 will sterilized by a spra from fixtures 84, 86 and the s ray gun 88. The closure assem ly 56 will then be opened anti the worker will enter the specimen room 22 to position the specimen container 32, as shown in FIG. 5. The worker will then reverse the process to leave the specimen room and the anteroom.

In view of the foregoing remarks, it is apparent that the I novel closure assemblies 56 and 58 facilitate movements of the worker 70 between the surrounding environment and the specimen room 22. Each of the closure assemblies 56 and 53 includes a flexible generally tubular member 114 having a central passage 118. A first end portion 90 of the tubular member 114 is sealed to the flange 50. The second end portion 62 of the tubular member 114 is movable relative to the first end portion 90 from an open position in substantial alignment with the first end portion of the tubular member (see FIG. 7) to a closed position wherein the second end portion 62 of the tubular member extends into a reservoir of liquid (see FIG. 6). The passage 118 is then blocked and sealed by the liquid in the reservoir 66, to prevent contaminants from entering the anteroom 36 through the passage 1K8.

While particular embodiments of the invention have been shown, it should be understood, of course, that the invention is not limited thereto since many modifications may be made; and it is, therefore, contemplated to cover by the appended claims any such modifications as fall within the true spirit and scope of the invention.

lclaim:

1. An entryway assembly for a wall, said entryway assembly comprising: a generally tubular flexible passage-defining member having a first end portion fixedly supported by the wall and a second end portion moveable relative to said first end portion, said second end portion being movable from an open position in which a person can move through both said first and second end portions of said passage-defining member to a closed portion in which the second end portion of said passagedefining member is located in a reservoir of fluid to seal the entryway against the passage of contaminants.

2. An assembly as set forth in claim 1 further including: a

plurality of eyelets formed in said passage-defining member;

and a cable means extending through said eyelets and connected to a drive means, said drive means being energizable to move said passage-defining member from the open position to the closed position by moving said cable means in a first direction, said drive means being reversible to move said passage-defining member from the open position to the closed position by moving said cable means in a second direction.

3. An assembly comprising: a wall having an aperture formed therein; a reservoir of fluid positioned adjacent to the aperture; and a flexible closure assembly having a first end portion supported by said wall in a fixed relationship with the aperture and a second end portion which is movable relative to the aperture, said second end portion of the flexible closure assembly being movable from a first position in which the aperture is at least partially open to a second position in which the second end portion of the flexible closure assembly is located in said reservoir of fluid to seal the aperture.

4. An assembly as set forth in claim 3 further including: bar means mounted on the second end portion of said closure assembly to hold said closure assembly in said reservoir of fluid when said closure assembly is in the second position.

5. An assembly as set forth in claim 3 further including: drive means connected to said flexible closure assembly to move said closure assembly from said second position to said first position.

Claims (5)

1. An entryway assembly for a wall, said entryway assembly comprising: a generally tubular flexible passage-defining member having a first end portion fixedly supported by the wall and a second end portion moveable relative to said first end portion, said second end portion being movable from an open position in which a person can move through both said first and second end portions of Said passage-defining member to a closed portion in which the second end portion of said passage-defining member is located in a reservoir of fluid to seal the entryway against the passage of contaminants.

2. An assembly as set forth in claim 1 further including: a plurality of eyelets formed in said passage-defining member; and a cable means extending through said eyelets and connected to a drive means, said drive means being energizable to move said passage-defining member from the open position to the closed position by moving said cable means in a first direction, said drive means being reversible to move said passage-defining member from the open position to the closed position by moving said cable means in a second direction.

3. An assembly comprising: a wall having an aperture formed therein; a reservoir of fluid positioned adjacent to the aperture; and a flexible closure assembly having a first end portion supported by said wall in a fixed relationship with the aperture and a second end portion which is movable relative to the aperture, said second end portion of the flexible closure assembly being movable from a first position in which the aperture is at least partially open to a second position in which the second end portion of the flexible closure assembly is located in said reservoir of fluid to seal the aperture.

4. An assembly as set forth in claim 3 further including: bar means mounted on the second end portion of said closure assembly to hold said closure assembly in said reservoir of fluid when said closure assembly is in the second position.

5. An assembly as set forth in claim 3 further including: drive means connected to said flexible closure assembly to move said closure assembly from said second position to said first position.

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