US3572660A - Device for dispensing inhalable fluids - Google Patents

Device for dispensing inhalable fluids Download PDF

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Publication number
US3572660A
US3572660A US3572660DA US3572660A US 3572660 A US3572660 A US 3572660A US 3572660D A US3572660D A US 3572660DA US 3572660 A US3572660 A US 3572660A
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Prior art keywords
inlet
container
accordance
invention
nozzle
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
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Thomas J Mahon
Samuel Cherba
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General Electric Capital Corp
Professional Medical Products Inc
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Becton Dickinson and Co
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/10Preparation of respiratory gases or vapours
    • A61M16/14Preparation of respiratory gases or vapours by mixing different fluids, one of them being in a liquid phase
    • A61M16/16Devices to humidify the respiration air
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/06Sprayers or atomisers specially adapted for therapeutic purposes of the injector type
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S261/00Gas and liquid contact apparatus
    • Y10S261/65Vaporizers

Abstract

A self-containing device for dispensing inhalable fluids, such as nebulized medicinal preparations or humidified breathable gas, including a container formed of cutable plastic and a sealed inlet formation and sealed outlet formations capable of being removed or cut away to establish the inlet and outlets. The container has an assembly at the inlet for aspirating a liquid with a gas to form a spray and a baffle in conjunction with the container wall and liquid surface for nebulizing the aspirated spray. The outlet construction consists of a large diameter tube and a small diameter tube extending therefrom, with a cutable blister formation between the two tubes. The outermost end of the smaller diameter tube forms the sealed outlet.

Description

United States Patent Thomas J. Mahon Englewood;

Samuel Cherba, Totowa, NJ. [21] Appl. No. 660,170

[22] Filed Aug. 4, 1967 [45] Patented Mar. 30, 1971 [73] Assignee Becton, Dickinson and Company [72] lnventors [54] DEVICE FORDISPENSING INHALABLE FLUIDS 8 Claims, 7 Drawing Figs.

[52] U.S. Cl. 261/78, 128/186,128/194,222/400.7,222/541, 239/309, 239/338, 239/370, 261/122 [51] 'Int. Cl B05b1/16, A61m 11/02 [50] Field ofSearch 128/194,

186, 188 (inquired), 198; 26l/78.1, 134 (Inquired); 222/541 (lnquired), 400.7; 239/309,

Primary Examiner-Richard C. Pinkham Assistant Examiner-Paul E. Shapiro Attorney-Kane, Dalsimer, Kane, Sullivan & Kurucz ABSTRACT: A self-containing device for dispensing inhalable fluids, such as nebulized medicinal preparations or humidified breathable gas, including a container formed of cutable plastic and a sealed inlet formation and sealed outlet formations capable of being removed or cut away to establish the inlet and outlets. The container has an assembly at the inlet for aspirating a liquid with a gas to form a spray and a baffle in conjunction with the container wall and liquid surface for nebulizing the aspirated spray. The outlet construction consists of a large diameter tube and a small diameter tube extending therefrom, with a cutable blister formation between the two tubes. The outermost end of the smaller diameter tube forms the sealed outlet.

Patenfed March 30,1971 I 3,572,660

} I 2 Sheets-Sheet 1 THOMAS SFIMUEL CH BY 0 l IIIIIIIIIII I w V v 5 H 2 H w win m M I, H 11 W i r o q fl/ w HTTORNEV DEVICE FOR DISPENSING INHALABLE FLUIDS BACKGROUND OF THE INVENTION 1. Field of the Invention I The present invention relates to inhalation therapy and, more particularly; to inhalaters of the nebulizing or breathable gas humidifying type.

The present invention is concerned with such devices which are utilized for humidifying inhalable gas and treating pulmonary ailments with a preparation administered by inhalation. This is accomplished by direct inhalation of the preparation by the patient or breathing an atmosphere thereof.

2. Description of Prior Art Neubilizers of the prior art for medicinal preparations have several disadvantages. Among these is that as a reusable device they are subject to pollution and cannot be, effectively decontaminated to prevent pulmonary cross-infection from one patient to another.

SUMMARY OF THE INVENTION Accordingly, an object of the present invention is to provide a device which overcomes the disadvantages of such prior devices.

Another object is to provide an improved device including a completely sealed container for the medicinal preparation, which device is formed with inlet and outlet openings just prior to being used, whereby contamination of the device is averted.

Another object is to provide such a device which is. so economical in construction that it is expendable after use on a single patient, whereby cross-infection is prevented;

Another object is to provide such a device which more effectively prepares the inhalable fluid for administration.

A further object is to provide such a device which can be utilized in many different manners.

Other and further objects will be obvious upon an. understanding of the illustrative embodiment about to be described, or will be indicated inv the appended claims and various advantages notreferred to herein will occur to one skilled in the art upon employment of the invention in practice.

In accordance with the present invention, the foregoing objects are generally accomplished by providing a self-containing device which comprises a container for a liquid, and'inlet means for a gaseous fluid and outlet means for treated fluid at the upper end of the container, the inlet and outlet means being formed of plastic material and having an end formation for sealing the inlet and outlet means and being constructed and arranged to be removed or cut away to open the inlet and outlet means.

More specifically, the container may be equipped with. an aspirator near the inlet means including anozzle in fluid flow communication with the inlet means for directing the gaseous fluid downwardly and a second nozzle positioned crosswise and adjacent the first nozzle for the eduction of a spray of the liquid, and a bafile member adjacently below the nozzles onto which the spray of liquid is directed and in conjunction with the container wall and liquid surface to nebulize the same.

Alternatively, a porous gas diffusing element in fluid flow communication may be placed in the liquid, which is confined by the container and which causes the gas to be humidified.

BRIEF DESCRIPTION OF THE DRAWINGS In the drawings:

FIG. I is an elevational view, partly in section of a device in accordance with the present invention.

FIG. 2 is a top plan view of the device shown in FIG. 1.

FIG. 3 is a sectional view taken alongtheline 3-3 on FIG. 2 illustrating the details of the inlet section of the device.

FIG. d is a sectional view taken along the line 4-4 on FIG. 2 illustrating the details of the outlet section of the device.

FIG. 5 is an enlarged longitudinal sectional view of a combined aspirator and nebulizer assembly.

FIG. 6 is a view similar to FIG. 4 but illustrating an audible safety release valve applied to an open outlet.

FIG. 7 is an elevational view, partly in section, of another embodiment of the present invention.

DESCRIPTION OF THE PREFERRED EMBODIMENTS Referring now to FIGS. 1 to 5 of the drawings in detail, there is shown a nebulizer which generally comprises a container 10 having an inlet section 11 and an outlet section 12, both at the top of the container.

The inlet section 11 (FIG. 3) comprises a cylindrical column 14 extending upwardly from the container having a neck portion 15 at the upper end thereof, a body member 16 seated in the neck portion, a combined inlet fitting and cap closure 17 having a nozzle 18 for connection of a tube 19 for supplying air, oxygen or any other inhalable gas, and a coupling 20 for screw-threadedly securing the inlet fitting 17 on the neck portion over the body member 16. The inlet fitting 117 may be discarded in some instances and the coupling 20 used instead.

The body member 16. has a central bore 21 in fluid flow communication with a bore 23 of the inlet fitting 17 at its upper end, and has inserted therein at its lower end an aspirating and nebulizing assembly 22 (FIG. 5).

As best shown in FIGS, the assembly 22 has an upper bore section 24 terminating in a downwardly facing nozzle 25 at its lower end, and has a lower bore section 26 terminating in a nozzle 27 at its upper end which nozzle is positioned crosswise and adjacent to the nozzle 25. The assembly further has a baffle 28 directly beneath the nozzles andhas a siphon tube 29 inserted into the lower bore section 26 and extending to the bottom of the container (FIG. 1).

When a gas under pressure is introduced into the bore 23 of the inlet fitting 17, a blast of gas is directed across the nozzle 27 by the nozzle 25. This causes eduction of fluid in the container through the nozzle 27 in the form of an aspirated spray. This spray is caused to impinge upon the baffle 28 by the blast of gas discharged from the nozzle 25 which in turn impinges upon the surface of the fluid and the container wall to nebulize the spray to amicron size suitable for inhalation.

The outlet section 12 (FIG. 4) comprises a covered cylindrical column 30 extending upwardly from the container 10, a vertical tubular section 31 on the top of the column 30, and a horizontally extending tubular portion 32 to which may be attached a nasal cannula or catheter (not shown) for insertion into a nostril.

The container 10 and its integral outlet section 12 and the inlet fitting 17 are formed of a plastic material which can be readily cut by scissors. The nozzle 18 of the fitting 17 has a formation 36 at its upper end (FIG. 1) for sealing the same. The horizontal tubular portion 32 likewise has a formation 37 for sealing the same. Additional openings may be provided by rupture of blisterlike end formations 39 and 40 of thinner plastic material on the inlet and outlet section columns 14 and 30 respectively, for purposes to be described hereinafter. After placing sterile liquid L into the sterile container 10 and sealing the inlet fitting 17 onto the neck portion 15, the device is completely sealed, so that the liquid cannot be contaminated.

When the device is to be used, the inlet formation 36 is cut away and the outlet formation 37 is likewise cut away, as by scissors 41, after which one end of a tube, such as a cannula or catheter (not shown) is telescoped over the tube 32 and the other end inserted into a persons nostril. An inhalable gas is delivered by the tube 19 through the bore 23 of the inlet fitting 17 and aspiration and nebulization take place as already described. The nebulizedliquid is discharged through the tubular portion 32 which has been opened at the outlet formation 37.

There are shown three blister formations 39 (see FIG. 2) on the inlet section column 14 and these function as venturi or air suction openings when out. When an inhalable gas, such as oxygen is delivered by tube 19 or coupling 20, the concentration of oxygen with respect to air discharged may be varied, depending upon whether three, two, one or no formations 39, respectively, are cut.

There is shown one blister formation 40 (see FIGS. 1 and 2) on an annular protuberance 42 of the outlet section column 30 and this blister formation 40 is provided as a cutable surface to enable the scissors 41 to be readily inserted therethrough, so as to cut away the entire upper portion of protuberance 42 including tubular section 31 and tubular portion 32, after which the opened section of protuberance 42 is connected for face mask or hood application. The contents of the container are administered to a single patient and the entire device is discarded when treatment of the patient is completed or when the entire contents of the container have been discharged.

in FIG. 6, the formation 37 of the tubular portion 32 has been cut away and a coupling 42 having a whistle 43 thereon is shown connected to the portion 32. The coupling 42' has an outlet 44 for discharge of the nebulized preparation and the whistle 43, which includes a check valve, serves as an audible alarm to indicate that the outlet 44 of the device has encountered a blockage, so that the attendant is immediately alerted to this condition.

In FIG. 7, there is shown a humidifier for inhalable gas which comprises a container 50 for a liquid having an inlet section 51 and an outlet section 52 on the top thereof, a flexible tube 54 having one end connected to the inlet section 51, and a porous gas diffusing element 55 resting on the bottom of the container and being attached to the other end of the tube 54.

The inlet section 51 includes a nozzle 56 for the connection of a gas supply tube 57 and a formation 58 for sealing the upper end of the nozzle 56.

The outlet section 52 includes a vertical tubular section 59, and a horizontal tubular portion 52 having a formation 37 for sealing the same.

The container 50 and its integral outlet section 52 and the inlet nozzle 56 are constructed of thin plastic material which enables the sealing formations to be readily cut away.

In use, the inlet formation 58 and the outlet formation 37 are cut away and the gas is introduced into the inlet nozzle 56. The gas is directed through the tube 54 to the element 55 which diffuses the gas. The diffused gas, as it rises through the liquid, is humidified and is discharged from the device.

Here again the device is completely sealed before use and is discarded after use, as already described.

From the foregoing description it will be seen that the present invention provides an improved fluid dispensing device which cannot be contaminated prior to use and being inexpensive is discarded after use.

We claim:

1. A device for dispensing fluids, comprising:

a plastic container for the fluid having an inlet section and an outlet section;

means within said container for treating fluid introduced through the inlet section;

outlet means at said outlet section for discharging the treated fluid, said outlet means including a covered cylindrical column extending from the container and a tubular projection extending a predetermined distance from the cylindrical column, said tubular projection being of considerably smaller diameter than said column to permit connection of the outlet section to a relatively small diameter delivery tube; and

a blisterlike formation on a sidewall of the cylindrical column, said formation being adapted to be easily ruptured to cut away the tubular projection and the cover of the cylindrical column to provide a larger diameter outlet passage and to permit connection of a relatively large delivery tube to the outlet section.

2. The invention in accordance with claim 1, wherein the inlet section includes an extending tubular projection terminating in an annular protuberance forming a seal and adapted to be cut away and the tubular projection extending from the cylindrical column also tenninating in an annular protuberance forming a seal and adapted to be cut away, whereby the container is sealed until the protuberances are cut away.

3. The invention in accordance with claim 1, wherein the blisterlike formation is formed on an annular protuberance formed around the cylindrical column, the blister being frangible to allow for cutting away the entire annular protuberance including the cover and the tubular projection.

4. The invention in accordance with claim 1, wherein an audible safety release element is attached to said outlet means to indicate when said device has encountered a blockage during discharge of said treated fluid.

5. The invention in accordance with claim 1, wherein said inlet means includes means for introducing an inhalable gas under pressure into said container, an aspirator is positioned in said inlet section including a first nozzle in fluid flow communication with said inlet means for directing the gas downwardly, a second nozzle positioned crosswise and adjacent said first nozzle for the eduction of a spray of the fluid therefrom, a syphon tube in fluid flow communication with said second nozzle and extending downwardly into the container, and a baffle member adjacently below said nozzles onto which the spray of the fluid is directed to nebulize the same.

6. The invention in accordance with claim 5, additionally comprising a plurality of blister formations formed on said inlet section and positioned adjacent said first nozzle, said blister formations being adapted to be easily ruptured to provide air suction openings for varying the concentration of the inhalable gas.

7. The invention in accordance with claim 6, wherein there are three blister formations formed about the inlet section.

8. The invention in accordance with claim 1, wherein humidifying means including a porous diffusing element is positioned between said inlet and outlet sections.

Claims (7)

  1. 2. The invention in accordance with claim 1, wherein the inlet section includes an extending tubular projection terminating in an annular protuberance forming a seal and adapted to be cut away and the tubular projection extending from the cylindrical column also terminating in an annular protuberance forming a seal and adapted to be cut away, whereby the container is sealed until the protuberances are cut away.
  2. 3. The invention in accordance with claim 1, wherein the blisterlike formation is formed on an annular protuberance formed around the cylindrical column, the blister being frangible to allow for cutting away the entire annular protuberance including the cover and the tubular projection.
  3. 4. The invention in accordance with claim 1, wherein an audible safety release element is attached to said outlet means to indicate when said device has encountered a blockage during discharge of said treated fluid.
  4. 5. The invention in accordance with claim 1, wherein said inlet means includes means for introducing an inhalable gas under pressure into said container, an aspirator is positioned in said inlet section including a first nozzle in fluid flow communication with said inlet means for directing the gas downwardly, a second nozzle positioned crosswise and adjacent said first nozzle for the eduction of a spray of the fluid therefrom, a syphon tube in fluid flow communication with said second nozzle and extending downwardly into the container, and a baffle member adjacently below said nozzles onto which the spray of the fluid is directed to nebulize the same.
  5. 6. The invention in accordance with claim 5, additionally comprising a plurality of blister formations formed on said inlet section and positioned adjacent said first nozzle, said blister formations being adapted to be easily ruptured to provide air suction openings for varying the concentration of the inhalable gas.
  6. 7. The invention in accordance with claim 6, wherein there are three blister formations formed about the inlet section.
  7. 8. The invention in accordance with claim 1, wherein humidifying means including a porous diffusing element is positioned between said inlet and outlet sections.
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Cited By (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3690317A (en) * 1970-10-29 1972-09-12 Bendix Corp Sonic nebulizer
US3724454A (en) * 1971-02-04 1973-04-03 Bendix Corp Humidifier - nebulizer
US3744771A (en) * 1970-07-20 1973-07-10 Ahldea Corp Disposable liquid entraining system
US3793810A (en) * 1972-06-19 1974-02-26 American Hospital Supply Corp Defoaming device for medical humidifier
US3807445A (en) * 1972-06-19 1974-04-30 American Hospital Supply Corp Audible pressure relief valve for medical humidifier
US3825000A (en) * 1972-11-08 1974-07-23 Baxter Laboratories Inc Disposable humidifier
US3834682A (en) * 1972-06-19 1974-09-10 American Hospital Supply Corp Mixing column for medical humidifier and method of humidifying inhalable gases
US3834385A (en) * 1972-11-09 1974-09-10 Baxter Laboratories Inc Disposable humidifier
US3836079A (en) * 1972-08-02 1974-09-17 Becton Dickinson Co Fluid dispensing device
US3846518A (en) * 1972-06-19 1974-11-05 American Hospital Supply Corp Port system for medical humidifier container
US3852385A (en) * 1972-12-06 1974-12-03 Med Pak Corp Gas humidification apparatus
US3857909A (en) * 1973-04-11 1974-12-31 Co Huggins J & Ass Gas nebulizing apparatus
US3864440A (en) * 1972-01-21 1975-02-04 Respiratory Care Humidifier and heater for delivered gas
US3900029A (en) * 1973-10-26 1975-08-19 Irving Melnick Closed surgical evacuator
US3903216A (en) * 1969-09-10 1975-09-02 Respiratory Care Inhalation therapy apparatus
US3929128A (en) * 1972-11-09 1975-12-30 Baxter Laboratories Inc Disposable humidifier
US4030665A (en) * 1974-05-20 1977-06-21 Goldwell Gmbh Apparatus for foaming liquid cosmetic substances
US4039639A (en) * 1975-04-10 1977-08-02 Richard L. Kankel Liquid entraining system of the humidifier and nebulizer type
US4045525A (en) * 1974-06-19 1977-08-30 Huggins James A Gas humidification apparatus
US4054622A (en) * 1970-11-03 1977-10-18 Lester Victor E Combination nebulizer and humidifier
US4061698A (en) * 1975-04-18 1977-12-06 Aerwey Laboratories, Inc. Humidifier-nebulizer apparatus
US4134940A (en) * 1977-10-25 1979-01-16 Aerwey Laboratories, Inc. Humidifier adapter with audio relief valve
US4140735A (en) * 1977-08-15 1979-02-20 J. C. Schumacher Co. Process and apparatus for bubbling gas through a high purity liquid
US4243396A (en) * 1979-04-16 1981-01-06 Becton, Dickinson And Company Humidifier separator
US4338267A (en) * 1979-08-23 1982-07-06 Becton, Dickinson And Company Medical gas humidifier with audible pressure relief valve and method of use
US4401241A (en) * 1981-01-19 1983-08-30 Respiratory Care, Inc. Nebulizer bottle
WO1986000285A1 (en) * 1984-06-22 1986-01-16 Leeds And Micallef Co-dispenser
US4629590A (en) * 1984-10-15 1986-12-16 Cimco Nebulizer
US4951659A (en) * 1988-11-04 1990-08-28 Automatic Liquid Packaging, Inc. Nebulizer with cooperating disengageable on-line heater
US5110013A (en) * 1990-03-28 1992-05-05 Diversey Corporation System for dispensing liquid cleaning compounds
US5115952A (en) * 1990-07-26 1992-05-26 Jenkins John D Device for providing liquid fluid for cyclists
US5127539A (en) * 1989-05-26 1992-07-07 Nomix Manufacturing Company Limited Containers for liquids
US6129265A (en) * 1998-10-15 2000-10-10 Perryman; David G. Beverage container with entertainment features
WO2003072174A1 (en) * 2002-02-28 2003-09-04 Medel S.P.A. Pre-dosed container for a medicinal product and method for its construction
EP1514569A1 (en) * 2003-09-09 2005-03-16 Flow Meter S.p.A. Bubbling humidifier of a gas, in particular oxygen, used in a respiratory therapy
US20180071464A1 (en) * 2007-05-15 2018-03-15 Caddo Medical Technologies Llc Pre-Filled, Small-Volume Nebulizer and Method of Manufacture

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US2809634A (en) * 1956-08-07 1957-10-15 Murai Hirotada Inhaling and sniffing pipe
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US2586845A (en) * 1950-05-15 1952-02-26 Bain L Mckinnon Nebulizer for administering medicaments
US2882026A (en) * 1955-08-31 1959-04-14 Chemetron Corp Nebulizer
US2809634A (en) * 1956-08-07 1957-10-15 Murai Hirotada Inhaling and sniffing pipe
US2902269A (en) * 1956-09-10 1959-09-01 Chemetron Corp Diffuser type vaporizer
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Cited By (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3903216A (en) * 1969-09-10 1975-09-02 Respiratory Care Inhalation therapy apparatus
US3744771A (en) * 1970-07-20 1973-07-10 Ahldea Corp Disposable liquid entraining system
US3690317A (en) * 1970-10-29 1972-09-12 Bendix Corp Sonic nebulizer
US4054622A (en) * 1970-11-03 1977-10-18 Lester Victor E Combination nebulizer and humidifier
US3724454A (en) * 1971-02-04 1973-04-03 Bendix Corp Humidifier - nebulizer
US3864440A (en) * 1972-01-21 1975-02-04 Respiratory Care Humidifier and heater for delivered gas
US3846518A (en) * 1972-06-19 1974-11-05 American Hospital Supply Corp Port system for medical humidifier container
US3834682A (en) * 1972-06-19 1974-09-10 American Hospital Supply Corp Mixing column for medical humidifier and method of humidifying inhalable gases
US3793810A (en) * 1972-06-19 1974-02-26 American Hospital Supply Corp Defoaming device for medical humidifier
US3807445A (en) * 1972-06-19 1974-04-30 American Hospital Supply Corp Audible pressure relief valve for medical humidifier
US3836079A (en) * 1972-08-02 1974-09-17 Becton Dickinson Co Fluid dispensing device
US3825000A (en) * 1972-11-08 1974-07-23 Baxter Laboratories Inc Disposable humidifier
US3834385A (en) * 1972-11-09 1974-09-10 Baxter Laboratories Inc Disposable humidifier
US3929128A (en) * 1972-11-09 1975-12-30 Baxter Laboratories Inc Disposable humidifier
US3852385A (en) * 1972-12-06 1974-12-03 Med Pak Corp Gas humidification apparatus
US3857909A (en) * 1973-04-11 1974-12-31 Co Huggins J & Ass Gas nebulizing apparatus
US3900029A (en) * 1973-10-26 1975-08-19 Irving Melnick Closed surgical evacuator
US4030665A (en) * 1974-05-20 1977-06-21 Goldwell Gmbh Apparatus for foaming liquid cosmetic substances
US4045525A (en) * 1974-06-19 1977-08-30 Huggins James A Gas humidification apparatus
US4039639A (en) * 1975-04-10 1977-08-02 Richard L. Kankel Liquid entraining system of the humidifier and nebulizer type
US4061698A (en) * 1975-04-18 1977-12-06 Aerwey Laboratories, Inc. Humidifier-nebulizer apparatus
US4100235A (en) * 1975-04-18 1978-07-11 Aerwey Laboratories, Inc. Humidifier-nebulizer apparatus
US4140735A (en) * 1977-08-15 1979-02-20 J. C. Schumacher Co. Process and apparatus for bubbling gas through a high purity liquid
US4134940A (en) * 1977-10-25 1979-01-16 Aerwey Laboratories, Inc. Humidifier adapter with audio relief valve
US4243396A (en) * 1979-04-16 1981-01-06 Becton, Dickinson And Company Humidifier separator
US4338267A (en) * 1979-08-23 1982-07-06 Becton, Dickinson And Company Medical gas humidifier with audible pressure relief valve and method of use
US4401241A (en) * 1981-01-19 1983-08-30 Respiratory Care, Inc. Nebulizer bottle
WO1986000285A1 (en) * 1984-06-22 1986-01-16 Leeds And Micallef Co-dispenser
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