US3559226A - Tooth brush for interproximal areas - Google Patents

Tooth brush for interproximal areas Download PDF

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Publication number
US3559226A
US3559226A US734191A US3559226DA US3559226A US 3559226 A US3559226 A US 3559226A US 734191 A US734191 A US 734191A US 3559226D A US3559226D A US 3559226DA US 3559226 A US3559226 A US 3559226A
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United States
Prior art keywords
handle
wire members
brush
tooth brush
bristles
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Expired - Lifetime
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US734191A
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Robert L Burns
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ALABAMA MEDICAL CENTER FO, University of
ALABAMA MEDICAL CENTER FOUNDATION THE, University of
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ALABAMA MEDICAL CENTER FO, University of
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Application filed by ALABAMA MEDICAL CENTER FO, University of filed Critical ALABAMA MEDICAL CENTER FO, University of
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    • A—HUMAN NECESSITIES
    • A46—BRUSHWARE
    • A46B—BRUSHES
    • A46B7/00—Bristle carriers arranged in the brush body
    • A46B7/04—Bristle carriers arranged in the brush body interchangeably removable bristle carriers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
    • A61C15/00—Devices for cleaning between the teeth
    • A—HUMAN NECESSITIES
    • A46—BRUSHWARE
    • A46B—BRUSHES
    • A46B2200/00—Brushes characterized by their functions, uses or applications
    • A46B2200/10—For human or animal care
    • A46B2200/1066—Toothbrush for cleaning the teeth or dentures
    • A46B2200/108—Inter-dental toothbrush, i.e. for cleaning interdental spaces specifically

Definitions

  • This invention relates to a tooth brush for interproximal areas and more particularly to a brush which is adapted for use in prevention and control of periodontal disease and prevention of dental caries, that may develop on the exposed root surface resulting from periodontal treatment.
  • the interproximal area is usually the first to Show periodontal breakdown. It is also well established that the complete removal of plaque daily is imperative to prevent and arrest periodontal disease.
  • another object of my invention is to provide such a brush which may be designed for use with near-normal as well as the periodontally-treated mouth.
  • Another object of my invention is to provide a tooth brush of the character designated in which the bristles extend perpendicular to the tooth surface between teeth and which may be used from the lingual as well as the buccal side.
  • a further object of my invention is to provide a tooth brush of the character designated which is extremely simple of construction, economical of manufacture and one which may easily be used and then cleaned for reuse.
  • FIG. 1 is a side elevational view of the tooth brush
  • FIG. 2 is an enlarged side elevational view thereof, partly broken away and in section;
  • FIG. 3 is a fragmental view taken generally along the line 3-3 of FIG. 2;
  • FIG. 4 is an enlarged, fragmental view showing the means for securing the elongated bristle supporting member to the handleof the brush.
  • I show an elongated handle which is bent adjacent one end thereof as at 11 to define one end 12 which is adapted to carry the brush element and another end portion 13 which defines the handle proper for the brush.
  • a laterally opening passageway 14 is provided to the end portion '12 of the handle 10. The handle 10 is bent so that the passageway 14 extends in a substantially common plane with both end portions 12 and 13.
  • An elongated wire member 16 is bent on its self, as shown in FIGS. 1 and 2 to provide a pair of wire members which are twisted on each other with bristles 17 therebetween to define a relatively stitf elongated bristle supporting member.
  • the bristles 17 extend radially from a common axis and are fixedly secured in place as the wire members are twisted relative to each other. Also, as shown in FIGS. 1 and 2, the bristles 17 are provided along a longitudinally extending portion of the supporting wire members so that a substantial portion of the twisted 'Wire member 16 extends beyond the bristles 17 whereby this portion of the wire members 16 is adapted to be inserted through the passageway 14.
  • the bristles 17 are formed of a suitable flexible material, such as nylon, and all of the bristles are of substantially the same length, as shown in FIG. 3.
  • the end portion 12 of the handle 10 is threaded as at 18 for receiving a nut 19 whereby the nut may be rotated into firm and locking engagement with the wire members 16 to thus firmly secure the bristle supporting wire members in place.
  • the wire members 16 With the wire members 16 thus secured in place by the nut 19, the wire members extend in a direction generally perpendicular to the end portion 12 and extend in a direction to define an obtuse angle relative to the handle portion 13 whereby the bristles 17 carried by the wire members 16 may be easily inserted into the interproximal spaces and then supported rigidly for back-and-forth motion interproximally and through bifurcations and trifurcations.
  • a longitudinally extending recess 20 is provided in the side of the handle portion 12 and extends through the adjacent end of passageway 14 so that the wire members 16 may be bent at a right angle and then lie within recess 20.
  • the portions of the wire members 16 within recess 20 thus extend within the threaded opening in nut 19 so that the adjacent ends of the wire members 16 are held adjacent the handle portion 12 whereby the free ends of the wire members do not damage tissue adjacent thereto during use of the brush.
  • the brush element comprising the elongated bristle supporting member 16 and the bristles 17 is attached to the handle portion 12 by inserting the projecting ends of the wire members 16 through the passageway 14, as shown in FIG. ,4.
  • the projecting ends of the wire members 16 are then bent from the dotted line position to the solid line position shown in FIG. 4, whereby the nut 19 is free to pass over the Wire members 16 as they lie within recess 20.
  • the nut 19 is then rotated in a direction to move into engagement with the sides of the wire members 16, as shown, whereby the wire members are secured rigidly to the handle.
  • the wire members 16 are formed of stainless steel wire and variations in wire size and bristle size may be made to adapt the brush for use with various oral conditions. That is, a finer size wire and bristle may be used in the normal or near-normal situation while the heavier wire core and bristle may be used in the periodontally treated month.
  • an elongated handle having a laterally opening passageway therein for receiving said another longitudinally extending portion of said supporting member with the end of said handle carrying said supporting member being bent in a common plane with said passageway and extending at an angle to the remainder of the handle so that said supporting member extends at an obtuse angle relative to the said remainder of the handle,

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  • Health & Medical Sciences (AREA)
  • Dentistry (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Brushes (AREA)

Abstract

A TOOTH BRUSH FOR INTERPROXIMAL AREAS HAVING ELONGATED WIRE MEMBERS TWISTED ON EACH OTHER WITH RADIALLY EXTENDING BRISTLES FIXEDLY SECURED IN PLACE THEREBETWEEN. A LATERALLY OPENING PASSAGEWAY IS PROVIDED IN AN ELONGATED HANDLE FOR RECEIVING ENDS OF THE TWISTED WIRE MEMBERS WHICH ARE SECURED IN PLACE BY AN ADJUSTABLE RETAINING MEMBER, THE HANDLE BEING BENT TO POSITION THE WIRE MEMBERS AT AN OBTUSE ANGLE RELATIVE TO THE REMAINDER OF THE HANDLE.

Description

Feb. 2 1971 R. L. BURNS TOOTH BRUSH FOR INTERPROXIMAL AREAS Filed May 31, 1968 INVIL'N'IIIR. Faber! 1.. Burns 4 ztomeys United States Patent 3,559,226 TOOTH BRUSH FOR INTERPROXIMAL AREAS Robert L. Burns, Lexington, Ky., assignor to The University of Alabama Medical Center Foundation, a corporation of Alabama Filed May 31, 1968, Ser. No. 734,191 Int. Cl. A46b 3/10, 9/04 US. Cl. 15-167 1 Claim ABSTRACT OF THE DISCLOSURE This invention relates to a tooth brush for interproximal areas and more particularly to a brush which is adapted for use in prevention and control of periodontal disease and prevention of dental caries, that may develop on the exposed root surface resulting from periodontal treatment. As is well known in the art to which my invention relates, the interproximal area is usually the first to Show periodontal breakdown. It is also well established that the complete removal of plaque daily is imperative to prevent and arrest periodontal disease. Many interdental stimulating and cleansing aides have been proposed, such as floss, rubber tips, tooth picks of all shapes, yarn, gauze, irrigation devices, tufted interproximal brushes, pipe cleaners, stainless steel twisted brushes as Well as the con ventional tooth brush. Such stimulating and cleansing aides have been unsatisfactory due to the fact that the cleaning elements or bristles extend parallel to the surface between teeth rather than extending perpendicular to the tooth surface between teeth. Also, such aides are difficult to use and are not adapted for reuse.
In addition to providing a tooth brush which shall be adapted to remove plaque in the interproximal area in the treatment of periodontal disease, another object of my invention is to provide such a brush which may be designed for use with near-normal as well as the periodontally-treated mouth.
Another object of my invention is to provide a tooth brush of the character designated in which the bristles extend perpendicular to the tooth surface between teeth and which may be used from the lingual as well as the buccal side.
A further object of my invention is to provide a tooth brush of the character designated which is extremely simple of construction, economical of manufacture and one which may easily be used and then cleaned for reuse.
A tooth brush embodying features of my invention is illustrated in the accompanying drawing forming a part of this application, in which:
FIG. 1 is a side elevational view of the tooth brush;
FIG. 2 is an enlarged side elevational view thereof, partly broken away and in section;
FIG. 3 is a fragmental view taken generally along the line 3-3 of FIG. 2; and,
FIG. 4 is an enlarged, fragmental view showing the means for securing the elongated bristle supporting member to the handleof the brush.
Referring now to the drawing for a better understanding of my invention, I show an elongated handle which is bent adjacent one end thereof as at 11 to define one end 12 which is adapted to carry the brush element and another end portion 13 which defines the handle proper for the brush. A laterally opening passageway 14 is provided to the end portion '12 of the handle 10. The handle 10 is bent so that the passageway 14 extends in a substantially common plane with both end portions 12 and 13.
An elongated wire member 16 is bent on its self, as shown in FIGS. 1 and 2 to provide a pair of wire members which are twisted on each other with bristles 17 therebetween to define a relatively stitf elongated bristle supporting member. The bristles 17 extend radially from a common axis and are fixedly secured in place as the wire members are twisted relative to each other. Also, as shown in FIGS. 1 and 2, the bristles 17 are provided along a longitudinally extending portion of the supporting wire members so that a substantial portion of the twisted 'Wire member 16 extends beyond the bristles 17 whereby this portion of the wire members 16 is adapted to be inserted through the passageway 14. The bristles 17 are formed of a suitable flexible material, such as nylon, and all of the bristles are of substantially the same length, as shown in FIG. 3.
The end portion 12 of the handle 10 is threaded as at 18 for receiving a nut 19 whereby the nut may be rotated into firm and locking engagement with the wire members 16 to thus firmly secure the bristle supporting wire members in place. With the wire members 16 thus secured in place by the nut 19, the wire members extend in a direction generally perpendicular to the end portion 12 and extend in a direction to define an obtuse angle relative to the handle portion 13 whereby the bristles 17 carried by the wire members 16 may be easily inserted into the interproximal spaces and then supported rigidly for back-and-forth motion interproximally and through bifurcations and trifurcations.
As shown in FIG. 4, a longitudinally extending recess 20 is provided in the side of the handle portion 12 and extends through the adjacent end of passageway 14 so that the wire members 16 may be bent at a right angle and then lie within recess 20. The portions of the wire members 16 within recess 20 thus extend within the threaded opening in nut 19 so that the adjacent ends of the wire members 16 are held adjacent the handle portion 12 whereby the free ends of the wire members do not damage tissue adjacent thereto during use of the brush.
From the foregoing description, the assembly and operation of my improved tooth brush will be readily understood. The brush element comprising the elongated bristle supporting member 16 and the bristles 17 is attached to the handle portion 12 by inserting the projecting ends of the wire members 16 through the passageway 14, as shown in FIG. ,4. The projecting ends of the wire members 16 are then bent from the dotted line position to the solid line position shown in FIG. 4, whereby the nut 19 is free to pass over the Wire members 16 as they lie within recess 20. The nut 19 is then rotated in a direction to move into engagement with the sides of the wire members 16, as shown, whereby the wire members are secured rigidly to the handle. Since the nylon bristles 17 are held in the twisted Wire member 16 whereby they project radially therefrom, the bristles 17 extend in a direction perpendicular to the surface to be cleaned between teeth rather than extending in a direction parallel to such surfaces. Preferably, the wire members 16 are formed of stainless steel wire and variations in wire size and bristle size may be made to adapt the brush for use with various oral conditions. That is, a finer size wire and bristle may be used in the normal or near-normal situation while the heavier wire core and bristle may be used in the periodontally treated month. After insertion of the brush element consisting of the wire members 16 and the bristles 17 between the teeth to be cleaned, the brush is moved back and forth whereby the elongated wire members 16 move longitudinally to remove plaque on the tooth surfaces in the interproximal area.
From the foregoing, it will be seen that I have devised an improved tooth brush for interproximal areas. By providing a tooth brush wherein the bristles extend perpendicular to the surfaces to be cleaned between teeth rather than extending parallel thereto, a more eificient cleaning action is obtained. Also, by providing a brush element which is detachably connected to a handle member, together with means securing the projecting or free ends of the twisted wire members in place, the brush elements may be readily removed from the handle for cleaning or replacement and at the same time the tissue of the mouth is not damaged by use of the brush. Furthermore, by providing a handle which supports the elongated brush element at an obtuse angle relative to the handle proper, the brush element may be readily inserted into the interproximal spaces for cleaning surfaces adjacent thereto.
While I have shown my invention in but one form, it will be obvious to those skilled in the art that it is not so limited, but is susceptible of various other changes and modifications without departing from the spirit thereof.
What I claim is:
1. In a tooth brush for interproximal areas:
(a) elongated wire members twisted on each other to define a relatively stiff, elongated bristle supporting member,
(b) radially extending bristles radiating from a common axis and fixedly secured in place between the twisted wire members along a longitudinally extending portion of said supporting member in position to extend perpendicular to the opposed tooth surfaces of adjacent teeth while said bristle supporting member is between adjacent teeth with another longitudinally extending portion of said supporting member projecting beyond the bristles,
(c) an elongated handle having a laterally opening passageway therein for receiving said another longitudinally extending portion of said supporting member with the end of said handle carrying said supporting member being bent in a common plane with said passageway and extending at an angle to the remainder of the handle so that said supporting member extends at an obtuse angle relative to the said remainder of the handle,
((1) external threads on said handle adjacent said passageway,
(e) a movable retaining member having a threaded opening therethrough engaging said external threads and disposed to secure said another longitudinally extending portion in place within said passageway, and
(f) there being a longitudinally extending recess in said handle communicating with said laterally opening passageway for receiving said another longitudinally extending portion of said supporting member so that said another longitudinally extending portion passes inwardly of said threaded opening in said movable retaining member.
References Cited UNITED STATES PATENTS 592,838 11/1397 Solem 15-146 1,296,067 3/1919 Fuller 15206 2,573,201 10/1951 Kelley etal 15-206X 3,204,275 9/1965 Baker 15--167X WALTER A. SCHEEL, Primary Examiner L. G. MACHLIN, Assistant Examiner US. Cl. X.R.
US734191A 1968-05-31 1968-05-31 Tooth brush for interproximal areas Expired - Lifetime US3559226A (en)

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Cited By (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3939520A (en) * 1974-06-13 1976-02-24 Axelsson P A T Tooth brush
US4030199A (en) * 1975-05-12 1977-06-21 E-Z Floss Handle for disposable appliance
US4053959A (en) * 1976-01-30 1977-10-18 Wiley Corless W Brush for teeth and gums
US4222143A (en) * 1979-03-16 1980-09-16 John O. Butler Company Interproximal brush handle
US4319377A (en) * 1980-08-25 1982-03-16 John O. Butler Company Interproximal toothbrush
FR2494971A1 (en) * 1980-10-22 1982-06-04 Esro Ag BRUSH
US4387479A (en) * 1981-05-14 1983-06-14 Block Drug Company, Inc. Interproximal toothbrush
US4564035A (en) * 1984-09-21 1986-01-14 Turner Tomie L Toothpick holder
WO1986002532A1 (en) * 1984-10-25 1986-05-09 Curaden Ag Device for cleaning interdental spacings
US4691404A (en) * 1985-02-21 1987-09-08 John O. Butler Company Toothbrush
US4710996A (en) * 1986-08-12 1987-12-08 John O. Butler Company Interdental brush handle
US4780923A (en) * 1987-11-30 1988-11-01 The Gillette Company Interproximal brush device having hinged brush retainer cap
US4809389A (en) * 1988-01-05 1989-03-07 Curaden Ag Interdental cleaning device
US4941227A (en) * 1989-01-25 1990-07-17 Sussman Harold I Device for cleaning dental implant posts
US5027467A (en) * 1990-02-06 1991-07-02 John O. Butler Company Toothbrush
US5201091A (en) * 1990-02-06 1993-04-13 John O. Butler Company Toothbrush
US5283924A (en) * 1990-09-21 1994-02-08 Gillette Canada, Inc. Interdental foam brush and treatment gel combination therewith
US5313684A (en) * 1991-08-30 1994-05-24 Georg Karl Geka-Brush Gmbh Dental brush holding device
US5331708A (en) * 1991-10-16 1994-07-26 Ponzini S.P.A. Interdental tooth-brush
US5333346A (en) * 1990-02-06 1994-08-02 John O. Butler Company, Inc. Toothbrush
US5347675A (en) * 1990-02-06 1994-09-20 John O. Butler Company, Inc. Toothbrush
US5435033A (en) * 1994-07-18 1995-07-25 Millner; Don E. Interdental toothcleaner holder
US5488751A (en) * 1994-07-20 1996-02-06 John O. Butler Company Interdental toothbrush
US5758382A (en) * 1995-09-12 1998-06-02 John O. Butler Company, Inc. Interdental brush handle
US5851116A (en) * 1996-03-11 1998-12-22 Margolis; Brian S. Interproximal cleaner and method of use
US5896615A (en) * 1997-04-28 1999-04-27 Colgate-Palmolive Company Interdental brush
US5940923A (en) * 1997-08-01 1999-08-24 Gunning; Colleen K. Dental implant cleaning system
US20100210968A1 (en) * 2007-07-17 2010-08-19 Histologics Llc Frictional trans-epithelial tissue disruption and collection apparatus and method of inducing and/or augmenting an immune response
US20110067191A1 (en) * 2009-09-22 2011-03-24 Atkin Joshua D Personal Hygiene Brush
US20110172557A1 (en) * 2007-07-17 2011-07-14 Histologics Llc Frictional trans-epithelial tissue disruption collection apparatus and method of inducing an immune response
US8887339B2 (en) 2012-08-27 2014-11-18 Moshe BARZEL Toothbrush with movable bristles sets
US9044213B1 (en) 2010-03-26 2015-06-02 Histologics, LLC Frictional tissue sampling and collection method and device
US9131768B2 (en) 2011-05-09 2015-09-15 Sunstar Americas, Inc. Dental hygiene device
WO2016185487A1 (en) 2015-05-21 2016-11-24 Global Dent Aids Pvt. Ltd An interdental brush with a protective tip
USD810292S1 (en) * 2016-06-17 2018-02-13 Su Lin Chou Interdental brushes handle
US10201332B1 (en) 2012-12-03 2019-02-12 Healoe Llc Device and method of orienting a biopsy device on epithelial tissue
US10702359B2 (en) 2016-12-01 2020-07-07 Ken E Clark Dental implant cleaning systems and methods
US11013466B2 (en) 2016-01-28 2021-05-25 Healoe, Llc Device and method to control and manipulate a catheter
US20220287809A1 (en) * 2021-03-12 2022-09-15 Kurt G. Vest Flosser

Cited By (57)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3939520A (en) * 1974-06-13 1976-02-24 Axelsson P A T Tooth brush
US4030199A (en) * 1975-05-12 1977-06-21 E-Z Floss Handle for disposable appliance
US4053959A (en) * 1976-01-30 1977-10-18 Wiley Corless W Brush for teeth and gums
US4222143A (en) * 1979-03-16 1980-09-16 John O. Butler Company Interproximal brush handle
DE2924758A1 (en) * 1979-03-16 1980-09-18 Butler John O Co HANDLE FOR INTERPROXIMAL BRUSHES
US4319377A (en) * 1980-08-25 1982-03-16 John O. Butler Company Interproximal toothbrush
FR2494971A1 (en) * 1980-10-22 1982-06-04 Esro Ag BRUSH
US4387479A (en) * 1981-05-14 1983-06-14 Block Drug Company, Inc. Interproximal toothbrush
US4564035A (en) * 1984-09-21 1986-01-14 Turner Tomie L Toothpick holder
WO1986002532A1 (en) * 1984-10-25 1986-05-09 Curaden Ag Device for cleaning interdental spacings
US4751761A (en) * 1984-10-25 1988-06-21 Curaden Ag. Device for cleaning interdental spaces
US4691404A (en) * 1985-02-21 1987-09-08 John O. Butler Company Toothbrush
US4710996A (en) * 1986-08-12 1987-12-08 John O. Butler Company Interdental brush handle
AU599685B2 (en) * 1986-08-12 1990-07-26 John O. Butler Company Interdental brush handle
US4780923A (en) * 1987-11-30 1988-11-01 The Gillette Company Interproximal brush device having hinged brush retainer cap
US4809389A (en) * 1988-01-05 1989-03-07 Curaden Ag Interdental cleaning device
US4941227A (en) * 1989-01-25 1990-07-17 Sussman Harold I Device for cleaning dental implant posts
US5027467A (en) * 1990-02-06 1991-07-02 John O. Butler Company Toothbrush
US5201091A (en) * 1990-02-06 1993-04-13 John O. Butler Company Toothbrush
US5333346A (en) * 1990-02-06 1994-08-02 John O. Butler Company, Inc. Toothbrush
US5347675A (en) * 1990-02-06 1994-09-20 John O. Butler Company, Inc. Toothbrush
US5283924A (en) * 1990-09-21 1994-02-08 Gillette Canada, Inc. Interdental foam brush and treatment gel combination therewith
US5313684A (en) * 1991-08-30 1994-05-24 Georg Karl Geka-Brush Gmbh Dental brush holding device
US5331708A (en) * 1991-10-16 1994-07-26 Ponzini S.P.A. Interdental tooth-brush
US5435033A (en) * 1994-07-18 1995-07-25 Millner; Don E. Interdental toothcleaner holder
US5488751A (en) * 1994-07-20 1996-02-06 John O. Butler Company Interdental toothbrush
DE19522502A1 (en) * 1994-07-20 1996-02-08 Butler John O Co Interdental toothbrush
DE19522502C2 (en) * 1994-07-20 2000-02-17 Butler John O Co Interdental brush handle and method for forming an interdental brush handle
US5758382A (en) * 1995-09-12 1998-06-02 John O. Butler Company, Inc. Interdental brush handle
US5851116A (en) * 1996-03-11 1998-12-22 Margolis; Brian S. Interproximal cleaner and method of use
US5896615A (en) * 1997-04-28 1999-04-27 Colgate-Palmolive Company Interdental brush
US5940923A (en) * 1997-08-01 1999-08-24 Gunning; Colleen K. Dental implant cleaning system
US10258780B2 (en) 2007-07-17 2019-04-16 Histologics, LLC Frictional trans-epithelial tissue disruption collection apparatus and method of inducing an immune response
US9393394B2 (en) 2007-07-17 2016-07-19 Histologics, LLC Frictional trans-epithelial tissue disruption and collection apparatus and method of inducing or augmenting an immune response
US20110172557A1 (en) * 2007-07-17 2011-07-14 Histologics Llc Frictional trans-epithelial tissue disruption collection apparatus and method of inducing an immune response
US9687642B2 (en) 2007-07-17 2017-06-27 Histologics, LLC Frictional trans-epithelial tissue disruption and collection apparatus and method of inducing or augmenting an immune response
US8652067B2 (en) 2007-07-17 2014-02-18 Histologics, LLC Frictional trans-epithelial tissue disruption and collection apparatus and method of inducing and/or augmenting an immune response
US8795197B2 (en) 2007-07-17 2014-08-05 Histologics, LLC Frictional trans-epithelial tissue disruption collection apparatus and method of inducing an immune response
US11213664B2 (en) 2007-07-17 2022-01-04 Histologics, LLC Frictional trans-epithelial tissue disruption collection apparatus and method of inducing an immune response
US9895140B1 (en) 2007-07-17 2018-02-20 Histologics, LLC Frictional trans-epithelial tissue disruption collection apparatus and method of inducing an immune response
US20100210968A1 (en) * 2007-07-17 2010-08-19 Histologics Llc Frictional trans-epithelial tissue disruption and collection apparatus and method of inducing and/or augmenting an immune response
US9282951B2 (en) 2007-07-17 2016-03-15 Histologics, LLC Frictional trans-epithelial tissue disruption collection apparatus and method of inducing an immune response
US8505148B2 (en) 2009-09-22 2013-08-13 Joshua D. Atkin Personal hygiene brush
US20110067191A1 (en) * 2009-09-22 2011-03-24 Atkin Joshua D Personal Hygiene Brush
US9044213B1 (en) 2010-03-26 2015-06-02 Histologics, LLC Frictional tissue sampling and collection method and device
US10149666B2 (en) 2010-03-26 2018-12-11 Histologics Llc Frictional tissue sampling and collection method and device
US9833061B2 (en) 2011-05-09 2017-12-05 Sunstar Americas, Inc. Dental hygiene device
US9131768B2 (en) 2011-05-09 2015-09-15 Sunstar Americas, Inc. Dental hygiene device
US8887339B2 (en) 2012-08-27 2014-11-18 Moshe BARZEL Toothbrush with movable bristles sets
US10201332B1 (en) 2012-12-03 2019-02-12 Healoe Llc Device and method of orienting a biopsy device on epithelial tissue
US11571188B1 (en) 2012-12-03 2023-02-07 Healoe Llc Device and method for locating and retaining biopsy sampling device on epithelial tissue
WO2016185487A1 (en) 2015-05-21 2016-11-24 Global Dent Aids Pvt. Ltd An interdental brush with a protective tip
US11013466B2 (en) 2016-01-28 2021-05-25 Healoe, Llc Device and method to control and manipulate a catheter
USD810292S1 (en) * 2016-06-17 2018-02-13 Su Lin Chou Interdental brushes handle
US10702359B2 (en) 2016-12-01 2020-07-07 Ken E Clark Dental implant cleaning systems and methods
US20220287809A1 (en) * 2021-03-12 2022-09-15 Kurt G. Vest Flosser
US11844661B2 (en) * 2021-03-12 2023-12-19 Kurt G. Vest Flosser

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