US3537453A - Microliter syringe having disposable parts - Google Patents

Microliter syringe having disposable parts Download PDF

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Publication number
US3537453A
US3537453A US713084A US3537453DA US3537453A US 3537453 A US3537453 A US 3537453A US 713084 A US713084 A US 713084A US 3537453D A US3537453D A US 3537453DA US 3537453 A US3537453 A US 3537453A
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US
United States
Prior art keywords
barrel
syringe
capillary tube
plunger
bore
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
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US713084A
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English (en)
Inventor
Edward L Drummond
Michael E Drummond
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
DRUMMOND INSTR CO
Drummond Instrument Co
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DRUMMOND INSTR CO
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by DRUMMOND INSTR CO filed Critical DRUMMOND INSTR CO
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Publication of US3537453A publication Critical patent/US3537453A/en
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Expired - Lifetime legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31525—Dosing
    • A61M5/31531—Microsyringes, e.g. having piston bore diameter close or equal to needle shaft diameter

Definitions

  • Another object is to provide a microliter syringe embodying a barrel marked with measurement graduations in which is positioned a capillary tube into which fluid is drawn without contacting the surface of the barrel, the capillary tube being readily removed for disposal after usage and replaced by a new tube.
  • a further object is to provide a microliter syringe of the character described having a plunger operable within the tube for expelling the contents therefrom, the plunger being removable for cleaning or disposal.
  • a microliter syringe which may be in the form of a hypodermic syringe or transfer syringe and includes a barrel having measurement graduation markings thereon, a fluid-receiving tube removably positioned in the barrel, barrel closure members in the terminals of the barrel having locating bores for the tube, a plunger extending into the tube and movable longitudinally therethrough to expel fluid, and delivery means beyond the opposite closure member through which the fluid passes to the desired point; to provide a microliter syringe of the character described wherein the delivery means is a hypodermic needle fixed to a closure member and in communication with the tube within the barrel. and to provide a microliter syringe as described, wherein the delivery means comprises an extension of the tube, the closure member including gripping means for preventing accidental longitudinal movement of the tube with respect to the barrel.
  • FIG. I is an exploded view of a hypodermic syringe made in accordance with the present invention.
  • FIG. 2 is a longitudinal sectional view of the hypodermic syringe of FIG. 1, showing the latter in assembled position;
  • FIG. 3 is an enlarged, transverse sectional view taken along the line 3-3 of FIG. 2, looking in the direction ofthe arrows;
  • FIG. 4 is an exploded view of a transverse syringe constructed in accordance with the present invention.
  • FIG. 5 is a perspective view ofthe transfer syringe of FIG. 4, showing the syringe in assembled condition;
  • FIG. 6 is a longitudinal sectional view of the transfer syringe of FIGS. 4 and 5;
  • FIG. 7 is an enlarged, transverse sectional view taken along the line 7-7 of FIG. 6, looking in the direction of the arrows, and
  • FIG. 8 is an enlarged, fragmentary plan view of a section of the transfer syringe showing to advantage the barrel having graduation markings thereon and the relationship of the capillary tube and plunger with respect thereto.
  • FIGURES 1 to 3 DESCRIPTION OF FIGURES 1 to 3 tion of one face of which issues a cylindrical portion 22, which in turn issues into a further reduced cylindrical member 24.
  • the diameter of cylindrical portion 22 is substantially equal to the inner diameter of barrel 10 to provide a frictional fit of the closure member within the barrel terminal.
  • a central bore 26 extends through closure member 16, which bore is enlarged at the inner end of the closure member, as indicated at 27.
  • a hypodermic needle 28 is inserted into bore 26 of closure member 16 and adhesively secured or fused at 30 to the face of disc 20 opposite cylindrical portion 22.
  • Closure member 18 includes a disc 32, from the central portion of one face of which extends a reduced cylindrical portion 34.
  • the diameter of cylindrical portion 34 is substantially equal to the inner diameter of barrel [0 to permit a frictional fit of the closure member within the barrel.
  • a central bore or clearance hole 36 extends completely through disc 32 and cylindrical portion 34 of closure member 18, the bore being flared at the inner terminal of the closure member, as indicated at 38.
  • a capillary tube 40 having a longitudinal bore 42 is positioned within, and in spaced relation to, the inner periphery of barrel If), the capillary tube being maintained in axial alignment with the barrel by means of a force fit into enlarged bore 27 of closure member 16 at one end, and extension through clearance hole 36 of closure member 44.
  • the diameter of bore or clearance hole 36 is slightly larger than the diameter of capillary tube 40 to permit ready insertion of the tube therein and facile removal therefrom.
  • a plunger generally designated 44 which includes a plunger body 46 that is preferably a straight piece of stainless steel wire, circular in cross section, the diameter of which is substantially the same as the diameter of bore 42 of capillary tube 40.
  • a plunger body 46 is set in any suitable manner into the central portion of a plunger cap or operating member 48.
  • Closure members 16 and 18 and plunger cap 48 are preferably of a molded plastic material such as Teflon which may be manufactured at a negligible cost.
  • Capillary tube 40 is precision made and is preferably redrawn glass tubing.
  • the operation of the microliter syringe of the present invention is conventional, the tip of hypodermic needle 28 being immersed in the fluid to be drawn into the syringe, following which plunger 44 is slowly withdrawn from capillary tube 40 until the desired measured amount, as indicated by graduations 12, is in bore 42 of capillary tube 40.
  • plunger 44 is slowly withdrawn from capillary tube 40 until the desired measured amount, as indicated by graduations 12, is in bore 42 of capillary tube 40.
  • the leading terminal of plunger body 46 forces the liquid in advance thereof to expel the fluid through hypodermic needle 28 and out of the bore at the terminal thereof.
  • barrel 10 is grasped firmly in one hand and a pull is exerted with the other hand on closure member 16 in a direction to withdraw the same from the terminal of the barrel.
  • Capillary tube 40 is removed from the barrel with closure member 16 and, it is contemplated by the present invention that the capillary tube and the closure member with the hypodermic needle connected thereto may be discarded as a unit, to obviate cleaning of these parts with which the fluid has come into contact.
  • Plunger 44 is removed from the opposite end of barrel l0 and may be either cleaned or discarded as desired. The negligible cost of these parts renders it economically feasible to dispose of them after use rather than to take the time and effort required for proper cleaning, particularly where contaminating or hard-to-clean liquids have been drawn into the syringe.
  • FIGS. 4 to 8 there is illustrated another form of the present invention which includes a barrel 50 having measure' ment graduations 52 marked on the outer periphery thereof, the barrel being provided with a central bore 54.
  • the terminals of barrel 50 are adapted to receive closure members designated 56 and 58.
  • Closure member 56 includes a disc 60, from the central portion of one face of which extends a cylindrical portion 62. From the opposite face of disc 60 extends a cylindrical member 64 which is externally threaded at 66. Cylindrical portion 64 in turn issues into a conical member 68, which is provided with a plurality of spaced longitudinal slits 70. A longitudinal bore 72 of predetermined diameter extends completely through closure member 56.
  • a knurled cylindrical collar 74 having a longitudinal bore 76, a portion of the wall defining the bore being threaded at 78, adjacent which threaded portion the wall is tapered as indicated at 79.
  • Closure member 58 includes a disc 80, the central portion of one face of which issues into a reduced cylindrical portion 82, the outer periphery of which frictionally engages the inner wall of barrel 50.
  • a longitudinal bore or clearance hole 84 extends through closure member 58 and is flared at 86 to facilitate insertion ofa capillary tube through the bore.
  • a capillary tube 88 having a bore 90 is positioned within barrel 50 with one terminal thereof extending through clearance hole 84, the extremity of the tube being flush with the outer limit ofdisc 80.
  • capillary tube 88 extends through and beyond barrel 50 and closure member 56 to permit use of the device as a transfer syringe.
  • Accidental longitudinal movement of capillary tube 88 with respect to barrel 50 is prevented by virtue of collar 74, which, when threadedly engaged with cylindrical portion 64, causes a limited flexing of conical portion 68 inwardly under urging of tapered section 79 of the collar, to grippingly engage the outer periphery of capillary tube 88.
  • the transfer syringe further includes a plunger 92 which includes a straight plunger body 94 which is preferably made of stainless steel, one terminal of which is set in a cap or operating member 96. It will be noted from a consideration of FIG. 6 that plunger body 92 extends completely through capillary tube 88 and terminates in a tip 98 which may be made of Teflon or other suitable material to force fluids in advance thereof when it is desired to expel the same from the transfer syringe. Intermediate the length of body 94, there is provided a marking 100, which, when the syringe is in the position shown in FIG. 6, coincides with one of the markings on the syringe and, for example, designates the IOU-lambda mark on the graduated barrel.
  • closure members 56 and 58 and cap 96 are also preferably of a molded construction such as Teflon and collar 74 is of metallic construction.
  • Capillary tube 88 is preferably of precision redrawn glass tubing.
  • plunger 92 is removed from capillary tube 88, following which collar 74 is loosened to permit facile removal oftube 88 for replacement by a new tube. As above indicated, plunger 92 may be either discarded and replaced by a new member or cleaned and reused.
  • a microliter syringe comprising:
  • closure members having longitudinal bores extending therethrough; at least one of said closure members being removable;
  • a disposable tubular member positioned within the axial bore of said barrel
  • said fluid-expelling member being movable longitudinally through the longitudinal bore of said tubular member
  • microliter syringe of claim 1 wherein both of said closure members are removable.
  • microliter syringe of claim I wherein said tubular member is a capillary tube.
  • said delivery means comprises a hypodermic needle fixed to one of said closure members;
  • hypodermic needle being in communication with the longitudinal bore of one of said closure member.
  • microliter syringe of claim 1 wherein:
  • said delivery means comprises an extension of said tubular member
  • a microliter syringe comprising:
  • closure members removably engaged with the terminals of said barrel
  • each of said closure members having longitudinal bores extending therethrough;
  • said capillary tube having a longitudinal bore in communication with the longitudinal bores of said closure members
  • a plunger removably engaged with said capillary tube and one of said closure members, said plunger including;
  • a plunger body extending through the longitudinal bore of the closure member into the longitudinal bore of said capillary tube
  • the inner terminal of said plunger body being of substantially the same diameter in cross section as the longitudinal bore of said tube;
  • fluid delivery means engaged with the other of said closure members and in communication with the longitudinal bore of said capillary tube, for conducting fluid to a point externally ofthe syringe.
  • microliter syringe of claim 6 wherein:
  • said fluid delivery means comprises an extension of said capillary tube through the longitudinal bore of said closure member and beyond the limits of said barrel;
  • microliter syringe of claim 8 wherein said means for grippingly engaging said capillary tube extension comprises:
  • said cylindrical collar including a threaded internal wall for operative engagement with the'threaded cylindrical portion: and g f. the internal wall of said cylindrical collar further including an internal tapered wall portion for exerting a force on said conical portion to grip said capillary tube extension.
  • microliter syringe of claim 6 wherein:
  • one terminal of said capillary tube is force fit into the longitudinal bore of one of said closure members

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  • Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
US713084A 1968-03-14 1968-03-14 Microliter syringe having disposable parts Expired - Lifetime US3537453A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US71308468A 1968-03-14 1968-03-14

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US3537453A true US3537453A (en) 1970-11-03

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US713084A Expired - Lifetime US3537453A (en) 1968-03-14 1968-03-14 Microliter syringe having disposable parts

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US (1) US3537453A (enrdf_load_stackoverflow)
GB (1) GB1232087A (enrdf_load_stackoverflow)
SE (1) SE349240B (enrdf_load_stackoverflow)

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3645252A (en) * 1968-12-05 1972-02-29 Gilford Instr Labor Inc Apparatus for sampling blood or the like fluid
US3791560A (en) * 1968-09-26 1974-02-12 Precision Sampling Corp Seals (psc-14)
US3923207A (en) * 1973-03-29 1975-12-02 Jintan Terumo Co Microliter syringe for dispensing small, accurately measured quantities of fluid specimens
US4224943A (en) * 1979-01-24 1980-09-30 Sorenson Research Co., Inc. Cannula and method for bidirectional blood flow
US4228808A (en) * 1977-09-08 1980-10-21 Avl Ag Device for the withdrawal of blood
US4664655A (en) * 1986-03-20 1987-05-12 Norman Orentreich High viscosity fluid delivery system
US4758234A (en) * 1986-03-20 1988-07-19 Norman Orentreich High viscosity fluid delivery system
US4950253A (en) * 1989-03-06 1990-08-21 Jerome Jacobs Needle ejector structure for a syringe
EP0443227A1 (en) * 1990-02-19 1991-08-28 Ito Corporation Analytical microsyringe
US20070287958A1 (en) * 2004-01-12 2007-12-13 Iscience Surgical Corporation Injector for Viscous Materials
US20090247955A1 (en) * 2008-03-27 2009-10-01 Iscience Interventional Corporation Microliter injector
US20180008182A1 (en) * 2016-07-08 2018-01-11 Tony Randall Wann Multi-function capillary tube syringe with retractable needle for arterial blood drawing

Cited By (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3791560A (en) * 1968-09-26 1974-02-12 Precision Sampling Corp Seals (psc-14)
US3645252A (en) * 1968-12-05 1972-02-29 Gilford Instr Labor Inc Apparatus for sampling blood or the like fluid
US3923207A (en) * 1973-03-29 1975-12-02 Jintan Terumo Co Microliter syringe for dispensing small, accurately measured quantities of fluid specimens
US4228808A (en) * 1977-09-08 1980-10-21 Avl Ag Device for the withdrawal of blood
US4224943A (en) * 1979-01-24 1980-09-30 Sorenson Research Co., Inc. Cannula and method for bidirectional blood flow
US4758234A (en) * 1986-03-20 1988-07-19 Norman Orentreich High viscosity fluid delivery system
US4664655A (en) * 1986-03-20 1987-05-12 Norman Orentreich High viscosity fluid delivery system
EP0238005A3 (en) * 1986-03-20 1989-01-25 Norman Orentreich High viscosity fluid delivery system
US4950253A (en) * 1989-03-06 1990-08-21 Jerome Jacobs Needle ejector structure for a syringe
EP0443227A1 (en) * 1990-02-19 1991-08-28 Ito Corporation Analytical microsyringe
US5063025A (en) * 1990-02-19 1991-11-05 Ito Corporation Analytical microsyringe with a superelastic plunger
US20070287958A1 (en) * 2004-01-12 2007-12-13 Iscience Surgical Corporation Injector for Viscous Materials
US7967772B2 (en) 2004-01-12 2011-06-28 Iscience Interventional Corporation Injector for viscous materials
US20090247955A1 (en) * 2008-03-27 2009-10-01 Iscience Interventional Corporation Microliter injector
US20180008182A1 (en) * 2016-07-08 2018-01-11 Tony Randall Wann Multi-function capillary tube syringe with retractable needle for arterial blood drawing

Also Published As

Publication number Publication date
GB1232087A (enrdf_load_stackoverflow) 1971-05-19
SE349240B (enrdf_load_stackoverflow) 1972-09-25

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