US3534135A - Method for setting hair with dithiourea and derivatives thereof - Google Patents

Method for setting hair with dithiourea and derivatives thereof Download PDF

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Publication number
US3534135A
US3534135A US603398A US3534135DA US3534135A US 3534135 A US3534135 A US 3534135A US 603398 A US603398 A US 603398A US 3534135D A US3534135D A US 3534135DA US 3534135 A US3534135 A US 3534135A
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United States
Prior art keywords
hair
dithiourea
solution
setting
derivatives
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Expired - Lifetime
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US603398A
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English (en)
Inventor
Theodor Wajaroff
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Procter and Gamble Deutschland GmbH
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Wella GmbH
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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00Preparations for care of the hair
    • A61Q5/04Preparations for permanent waving or straightening the hair
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/46Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur

Definitions

  • the present invention relates to setting or fixing hair, more particulraly to setting hair which, in softened condition has been subjected to permanent waving.
  • a hair setting composition and a method of setting hair are provided which will restore the disulfide bridges between protein chains of the keratin of the hair which were split by means of reducing agents such as thioglycolates in order to make the hair sufficiently deformable for the permanent waving of the same.
  • reducing agents such as thioglycolates
  • bifunctional compounds were suggested as fixing agents, which by reaction of their functional groups with the SH groups of adjacent protein chains are capable to form a molecular bridge, and thereby permanently set the hair in the shape given to the same.
  • these compounds, including the bridges between the protein chains are different from the compounds present in the natural hair structure and, furthermore, cause irreversible and disadvantageous changes in the structure of the hair.
  • Suitable for this purpose are several oxidizing agents and, in fact, for the setting of permanent waves, hydrogen peroxide and addition products thereof such as urea peroxide and alkali perborates as well as salts of oxygencontaining hydrohalic acids such as alkali metal bromates and chlorites have been used.
  • alkali metal polythionates were proposed for the fixing of permanent waves, because these last-mentioned compounds, due to their very mild oxidizing effect, would not cause any damage to the hair.
  • the last-mentioned compounds are incapable of achieving the desired degree of fixing of the hair so that permanently waved hair treated in this manner will not be sufficiently resistant against humidity or moisture and under such conditions will lose its shape. It appears that the effect of the polythionates is too weak to cause the conversion of a sufficiently large proportion of the SH groups of the softened hair into cross-lined SS bridges.
  • the softened permanently waved hair is effectively set without forming in the hair structure any compounds which are foreign to natural hair, by applying to the softened hair a hair setting composition which consists essentially of a carrier material which is compatible with hair and in which is distributed a salt of dithiourea (diformamidine disulfide) or of an N-alkyl derivative of dithiourea.
  • a hair setting composition which consists essentially of a carrier material which is compatible with hair and in which is distributed a salt of dithiourea (diformamidine disulfide) or of an N-alkyl derivative of dithiourea.
  • the above described effective salt is dissolved in an aqueous liquid as the carrier material and the N-alkyl derivative preferably is a N-lower alkyl derivative.
  • the effective proportion of the above described salts generally will be between about 2% by weight of the hair setting composition and a maximum percentage which equals the concentration of a saturated solution of the salt in the aqueous liquid.
  • hair setting composition as described above will cause substantial restoration of the initial disulfide bridges between the protein chains of the hair keratin which were split in order to soften the hair so as to make it amenable to waving or other deformation.
  • hair deformation is referred to herein generally as hair waving
  • the present invention is not limited to the setting or fixing of permanently waved hair but can also be utilized in connection with the setting or fixing of, for instance, straightened hair, or hair which for whatever reason had been softened under splitting of the above described disulfide bridges.
  • one or more salts of dithiourea or of N-alkyl derivatives thereof are used for the fixing or setting of the softened, for instance permanently waved, hair.
  • the salts of the N-alkyl derivatives which may be used in accordance with the present invention are preferably N-lower-alkyl derivatives, since higher alkyl derivatives of this kind are of markedly reduced effectiveness.
  • the type of the anion of these salts is substantially without significance.
  • the chlorides or bromides are used but good results are also obtained by utilizing other organic or inorganic salts of thiourea or of N-loWeralkyl derivatives thereof, for instance, nitrates or oxalates.
  • the salts which form the effective setting agent of the present invention have the following structural formula:
  • R denotes either hydrogen or an alkyl group, and the alkyl group preferably is methyl, ethyl or propyl. It will be noted that the structural formula includes four secondary valences C N.
  • the salts of dithiourea and derivatives thereof which are used according to the present invention are stable in solid condition and are also harmless when stored and used in solution since they tend neither to spontaneous decomposition nor is there any danger of inflammation.
  • the salts are used in an acidic aqueous solution since these salts have their best fixing effect in an acidic medium and, on the other hand, when applied in an acidic solution, the alkaline permanent waving solution will be quickly neutralized so that the conventional acidic rinse can be dispensed with.
  • dithiourea compounds which are utilized according to the present invention tend in weak acidic solutions slowly to split off colloidal sulfur. This phenomenon also takes place during contact of the hair setting composition of the present invention on the hair with alkaline hair waving solution. It is well known that elementary sulfur has a disinfecting and generally favorable effect on the scalp so that the slow formation of colloidal sulfur represents another favorable side effect of the present invention.
  • the effective salts which are utilized according to the present invention may be combined with suitable, preferable aqueous carrier substances which are compatible with hair, as well as with other preparations and additives of hair cosmetic preparations, such as emulsifiers, wetting agents, thickeners and the like.
  • the concentration of the salts of thiourea and/or the above described derivatives thereof in the hair setting composition according to the present invention generally will be at least equal to 2% of the weight of the hair setting composition and preferably equal to between about 5% and of the weight thereof.
  • the upper limit of the 4 concentration will be that of a saturated solution of the effective salt in the carrier liquid.
  • EXAMPLE I 8.0 g. dithiourea-dichloride and 0.8 g. sodiumlaurylsulfate (Texapon Z highly concentrated) are dissolved in ml. water, and the pH of the solution is 1.8.
  • One-half of the thus obtained solution is foamed onto the hair while the same is wound on curlers or rollers and allowed to react with the hair for about 3 minutes. Thereafter, the curlers or rollers are removed and the other half of the solution is foamed onto the hair and again allowed to react for 3 minutes. This is followed by rinsing, and thereby the hair setting is completed.
  • EXAMPLE II 12.0 g. dithiourea-dibromide and 1.0 g. laurylpyridinechloride are dissolved in ml. water, and the pH of the solution is 2.0.
  • the hair treatment is carried out as described in Example I.
  • EXAMPLE III 12.0 g. dithiourea-dichloride, 2.0 g. thiourea and 3.0 g. dry perfume (polyglycol 10,000 with 15% perfume oil) are dissolved in 100 ml. water, and the pH of the solution is 1.8.
  • One-half of the solution is applied to the hair while the same is wound on curlers and allowed to react for 3 minutes. Thereafter, the curlers are removed and the other half of the solution is applied to the hair and again allowed to react for 3 minutes, followed by rinsing with water.
  • EXAMPLE IV 30.9 g. dithiourea-dichloride and 22.0 g. disodiumhydrogenphosphate- 12 H O are dissolved in 500 ml. water, to form a solution having a pH of 4.0.
  • EXAMPLE V 20.0 g. N,N-diisopropyl-dithiourea-dibromide are dissolved in 500 ml. water, to form a solution having a pH of 2.2.
  • the hair is treated with the thus formed solution as described in Example IV.
  • EXAMPLE VI 10.0 g. N,N-diethyl-dithiourea-dibromide are dissolved in 100 ml. water, to form a solution having a pH of 2.2.
  • the hair is then set as described in Example III.
  • EXAMPLE VII 8.0 g. N,N-dimethyl-dithiourea-dibromide and 0.6 g. sodiumlaurylsulfate (Texapon Z, highly concentrated) are dissolved in 60 ml. water, to form a solution having a pH of 1.9.
  • the hair is treated with the thus formed solution, as described in Example I.
  • Method for setting hair which has been softened by splitting disulfide bridges between protein chains of the hair keratin, comprising the steps of applying to said thus softened hair a hair setting composition consisting essentially of an aqueous carrier which is compatible with hair and having distributed therethrough an effective amount of a substance selected from the group consisting of a water-soluble salt of diformamidine disulfide and N-lower alkyl derivatives thereof.
  • a method as defined in claim 1, wherein said salt is selected from the group consisting of chlorides, bromides, nitrates and oxalates.
  • said efi ective amount is equal to between about 2% by weight of said hair setting composition and the saturation concentration of said substance in said aqueous carrier.

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Cosmetics (AREA)
US603398A 1965-12-23 1966-12-20 Method for setting hair with dithiourea and derivatives thereof Expired - Lifetime US3534135A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DEW0040583 1965-12-23

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US3534135A true US3534135A (en) 1970-10-13

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US (1) US3534135A (enrdf_load_stackoverflow)
BE (1) BE686608A (enrdf_load_stackoverflow)
DE (1) DE1492257A1 (enrdf_load_stackoverflow)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3642429A (en) * 1967-10-26 1972-02-15 Oreal Cosmetic composition for treating hair
US3862221A (en) * 1967-08-02 1975-01-21 Oreal N,N{40 -di(hydroxymethylcarbamyl)cystamine

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2195623A (en) * 1937-09-01 1940-04-02 Monsanto Chemicals Sponge rubber
US2783272A (en) * 1956-05-08 1957-02-26 Du Pont Production of formamidine sulfinic acid
US2853132A (en) * 1955-06-17 1958-09-23 Ciba Ltd Pest combating composition and methods employing diformamidine sulfides

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2195623A (en) * 1937-09-01 1940-04-02 Monsanto Chemicals Sponge rubber
US2853132A (en) * 1955-06-17 1958-09-23 Ciba Ltd Pest combating composition and methods employing diformamidine sulfides
US2783272A (en) * 1956-05-08 1957-02-26 Du Pont Production of formamidine sulfinic acid

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3862221A (en) * 1967-08-02 1975-01-21 Oreal N,N{40 -di(hydroxymethylcarbamyl)cystamine
US3642429A (en) * 1967-10-26 1972-02-15 Oreal Cosmetic composition for treating hair

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Publication number Publication date
DE1492257A1 (de) 1969-11-06
BE686608A (enrdf_load_stackoverflow) 1967-02-15

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