US3498228A - Portable infusion pump - Google Patents
Portable infusion pump Download PDFInfo
- Publication number
- US3498228A US3498228A US634964A US3498228DA US3498228A US 3498228 A US3498228 A US 3498228A US 634964 A US634964 A US 634964A US 3498228D A US3498228D A US 3498228DA US 3498228 A US3498228 A US 3498228A
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- motor
- controlled rectifier
- transistor
- battery
- infusion pump
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
- A61M5/172—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic
Definitions
- Infusion pumps are devices for pumping intravenously or intra-arterially through a catheter drugs of one type or another. Often it is desirable to continuously inject carefully metered quantities of drugs into an ambulatory human.
- This invention provides an infusion apparatus, which may be portable, in which a battery may be employed to drive an electric motor through an electronic timing circuit.
- the timing circuit energizes the motor at accurately controlled intervals.
- the motor drives the infusion pump at a uniform rate throughout the life of the battery.
- the apparatus includes an arrangement for de-energizing the motor after the measured dosage has been delivered.
- the electronic timing circuit includes a simple arrangement for accurately manually controlling the frequency with which a volume of fluid is delivered by the pump.
- Another object of this invention is to provide an infusion apparatus, which may be portable, which delivers uniform quantities of fluid into a patients body throughout the life of the battery or portable power'source.
- Still another object of this invention is to provide an infusion apparatus, which may be portable, which can be quickly, accurately and easily controlled to thereby adjust the total quantity of fluid delivered to the body in a given period, such as a day.
- FIGURE 1 is a combined schematic and block repre sentation of one illustrative embodiment of this invention.
- FIGURE 2 is a pictorial and schematic representation of a cam and switch employed in FIGURE 1;
- FIGURE 3 is a diagrammatic illustration of the upper part of a human body with the infusion apparatus of the instant invention shown operatively associated therewith.
- a pump 10 which is of any convenient type employed in the infusion of liquids into the body and may be of the type disclosed in such patents as Vibber et al. Patent 2,925,814 or Corbin et al. Patent 3,252,623.
- the pump 10 is to be driven by a motor 16v through suitable mechanical coupling, as indicated by the dotted line 17 and has a discharge path 18 for infusing liquids into the body of an ambulatory patient as shown in FIGURE 3.
- the motor 16 is driven by the battery 12 and actuated by an electronic control system including a pair of resistors 20, 21 serially connected across the battery 14 and having inserted between them a diode 23.
- a variable resistor 25 has one terminal connected to terminal of battery 14 and the other terminal connected to the emitter of a transistor 27.
- the base of transistor 27 is connected intermediate diode 23 and resistor 21.
- the collector of 3,498,228 Patented Mar. 3, 1970 transistor 27 is connected to a capacitor 28, the opposite electrode of which is connected to common terminal 11 of batteries 12 and 14.
- the collector of transistor 27 is also connected to the emitter of a unijunction transistor 30.
- One of the bases of the unijunction transistor 30 is connected through a resistor 32 to terminal 15 of the battery 14.
- the other base of transistor 30 is connected through a resistor 34 to terminal 18 of battery 14.
- This second or other base electrode of the transistor 30 is also connected to a gate electrode 35 of a silicon controlled rectifier 36.
- the silicon controlled rectifier has its cathodeanode path serially connected between a brush 38 of the motor 16 and terminal 11 of batteries 12 and 14. The other brush of the motor 16 is connected to the terminal 13 of the battery 12.
- a resistor 40 is connected between the brushes of the motor 16 for the purpose of reducing the arcing of the motor and for maintaining the minimum sustaining current through the silicon controlled rectifier 36 during motor start up.
- Transistor 27 is biased to act as a constant current source to control the charging of capacitor 28. The current is fixed by the biased resistors 25, 20, 21 and diode 23. Diode 23 provides temperature compensation for transistor 27.
- the closing of switch 44 shorts the cathode-anode path of the silicon controlled rectifier 36 and the current through the controlled rectifier is dropped to zero and the controlled rectifier becomes non-conducting.
- the motor 16 continues to run until the cam control, indicated by the dotted line 45, opens switch 44. Meanwhile, capacitor 28 has begun to charge and the entire sequence is repeated.
- the accuracy of the metering function is dependent only upon the constant current generator, capacitor 28 and the unijunction transistor 30.
- the cam actuation of the switch 44 preserves the precise dosage for each pulse or each period of drive of the motor 16 since the shaft rotates exactly the same amount each time it is driven.
- the temperature compensation 23 and the resistor 32 enable high stability of the timing interval to be maintained over a wide temperature range.
- the important features of this invention include the precise control of the linearity of the system by means of a timing circuit which is linear over a wide range of battery voltages and temperatures. Too, the use of a cam actuated switch accurately controls the dosage per gating pulse or per duty cycle. Also, the cyclic feature provided by the timing circuit extends the life of the portable power source and hence provides increased reliability.
- the infusion system produces a linearity of dosage with respect to time and this linearity remains constant regardless of the rate of discharge of the batteries thus eliminating the possibility of a misdosage due to electrical or mechanical transients as may be experienced in a device which injects continuously.
- Portable infusion apparatus for dispensing a measured amount of fluid to an an ambulatory patient comprising,
- a battery controlled rectifier means coupled to said battery, a motor connected to said controlled rectifier means, a portable infusion pump having a discharge path to said patient coupled to said motor to be driven thereby during a predetermined amount of rotation of said motor, said pump dispensing a measured amount of fluid during said predetermined amount of rotation,
- unijunction oscillator means coupled to said controlled rectifier means for generating a series of pulses, each of said pulses triggering said controlled rectifier means into conduction to initiate said predetermined amount of rotation of said motor, said pulses occurring at predetermined equal intervals of time, said interval between pulses including the time required forsaid motor to complete said predetermined amount of rotation, whereby dispensing of fluid by said pump is initiated at predetermined equal intervals of time irrespective of the time required for said motor to complete said predetermined amount of rotation, and
- the apparatus of claim l'whe rein said-means for de-energizing said motor comprises a switch connected across said controlled rectifier means forconducting current around said controlled rectifier means and to said motor when said switch is actuated, and a cam associated with said motor for momentarily actuating said switch at the end of said predetermined amountv of rotation of said motor, whereby at the end of said predetermined amount of rotation said controlled rectifier means is rendered receptive to the next pulse from said oscillator means.
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- Health & Medical Sciences (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Description
March 3, 1970 c. A. BLUMLE ET AL 3,498,228
PORTABLE INFUSION PUMP Filed May 1. 1967 INVEN TOR CHARLES A.BLUMLE LEO J. BLUMLE 6080 12774, Six/0,1 finals ream W MIM /J5 United States Patent O 3,498,228 PORTABLE INFUSION PUMP Charles A. Blumle, 2968 S. Moreland, Cleveland, Ohio 44120, and Leo J. Blumle, 12300 La Plat-a, Silver Spring,
Filed May 1, 1967, Ser. No. 634,964 Int. Cl. F04b 49/02; B65h 5/28; H02h 7/08 US. Cl. 10325 2 Claims ABSTRACT OF THE DISCLOSURE Infusion pumps are devices for pumping intravenously or intra-arterially through a catheter drugs of one type or another. Often it is desirable to continuously inject carefully metered quantities of drugs into an ambulatory human. This invention provides an infusion apparatus, which may be portable, in which a battery may be employed to drive an electric motor through an electronic timing circuit.
BRIEF DESCRIPTION OF THE INVENTION In this infusion apparatus, the timing circuit energizes the motor at accurately controlled intervals. The motor drives the infusion pump at a uniform rate throughout the life of the battery. The apparatus includes an arrangement for de-energizing the motor after the measured dosage has been delivered. The electronic timing circuit includes a simple arrangement for accurately manually controlling the frequency with which a volume of fluid is delivered by the pump.
It is an object of this invention to provide an infusion apparatus, which may be portable, in which the frequency with which a volume of fluid is delivered can be selectively controlled.
Another object of this invention is to provide an infusion apparatus, which may be portable, which delivers uniform quantities of fluid into a patients body throughout the life of the battery or portable power'source.
Still another object of this invention is to provide an infusion apparatus, which may be portable, which can be quickly, accurately and easily controlled to thereby adjust the total quantity of fluid delivered to the body in a given period, such as a day.
These and various other objects, features and advantages of the invention will be more clearly understood from a reading of the detailed description of the invention in conjunction with the drawing in which:
'FIGURE 1 is a combined schematic and block repre sentation of one illustrative embodiment of this invention.
FIGURE 2 is a pictorial and schematic representation of a cam and switch employed in FIGURE 1; and
FIGURE 3 is a diagrammatic illustration of the upper part of a human body with the infusion apparatus of the instant invention shown operatively associated therewith.
Referring now to the drawing, there is depicted in block form a pump 10 which is of any convenient type employed in the infusion of liquids into the body and may be of the type disclosed in such patents as Vibber et al. Patent 2,925,814 or Corbin et al. Patent 3,252,623. The pump 10 is to be driven by a motor 16v through suitable mechanical coupling, as indicated by the dotted line 17 and has a discharge path 18 for infusing liquids into the body of an ambulatory patient as shown in FIGURE 3. The motor 16 is driven by the battery 12 and actuated by an electronic control system including a pair of resistors 20, 21 serially connected across the battery 14 and having inserted between them a diode 23. A variable resistor 25 has one terminal connected to terminal of battery 14 and the other terminal connected to the emitter of a transistor 27. The base of transistor 27 is connected intermediate diode 23 and resistor 21. The collector of 3,498,228 Patented Mar. 3, 1970 transistor 27 is connected to a capacitor 28, the opposite electrode of which is connected to common terminal 11 of batteries 12 and 14. The collector of transistor 27 is also connected to the emitter of a unijunction transistor 30. One of the bases of the unijunction transistor 30 is connected through a resistor 32 to terminal 15 of the battery 14. The other base of transistor 30 is connected through a resistor 34 to terminal 18 of battery 14. This second or other base electrode of the transistor 30 is also connected to a gate electrode 35 of a silicon controlled rectifier 36. The silicon controlled rectifier has its cathodeanode path serially connected between a brush 38 of the motor 16 and terminal 11 of batteries 12 and 14. The other brush of the motor 16 is connected to the terminal 13 of the battery 12. A resistor 40 is connected between the brushes of the motor 16 for the purpose of reducing the arcing of the motor and for maintaining the minimum sustaining current through the silicon controlled rectifier 36 during motor start up. Transistor 27 is biased to act as a constant current source to control the charging of capacitor 28. The current is fixed by the biased resistors 25, 20, 21 and diode 23. Diode 23 provides temperature compensation for transistor 27.
As this constant current generator charges the capacitor 28, the voltage across capacitor 28 rises until the unijunction transistor 30 triggers. Once transistor 30 has triggered, resistor 34 provides a discharge path for capacitor 28 to permit it to discharge at a rapid rate. Resistor 32 provides temperature compensation for the transistor 30. When transistor 30 triggers, a pulse is produced across resistor 34 and this pulse triggers silicon controlled rectifier 36. Once silicon controlled rectifier 36 is triggered o-r gated, the controlled rectifier remains conducting as long as current through it is above a certain level required to maintain this conduction as is well known in the art. Motor 16 continues to drive until a cam control, mounted on the motor shaft, closes switch 44 which cam control is indicated by a dotted line 45. The closing of switch 44 shorts the cathode-anode path of the silicon controlled rectifier 36 and the current through the controlled rectifier is dropped to zero and the controlled rectifier becomes non-conducting. The motor 16 continues to run until the cam control, indicated by the dotted line 45, opens switch 44. Meanwhile, capacitor 28 has begun to charge and the entire sequence is repeated. The accuracy of the metering function is dependent only upon the constant current generator, capacitor 28 and the unijunction transistor 30. The cam actuation of the switch 44 preserves the precise dosage for each pulse or each period of drive of the motor 16 since the shaft rotates exactly the same amount each time it is driven. The temperature compensation 23 and the resistor 32 enable high stability of the timing interval to be maintained over a wide temperature range.
In conclusion, the important features of this invention include the precise control of the linearity of the system by means of a timing circuit which is linear over a wide range of battery voltages and temperatures. Too, the use of a cam actuated switch accurately controls the dosage per gating pulse or per duty cycle. Also, the cyclic feature provided by the timing circuit extends the life of the portable power source and hence provides increased reliability. The infusion system produces a linearity of dosage with respect to time and this linearity remains constant regardless of the rate of discharge of the batteries thus eliminating the possibility of a misdosage due to electrical or mechanical transients as may be experienced in a device which injects continuously.
In accordance with the patent statutes, the principles of the present invention may be utilized in various Ways, numerous modifications and alterations being contemplated, substitution of parts and changes in construction being resorted to as desired.
We claim: 1. Portable infusion apparatus for dispensing a measured amount of fluid to an an ambulatory patient comprising,
a battery, controlled rectifier means coupled to said battery, a motor connected to said controlled rectifier means, a portable infusion pump having a discharge path to said patient coupled to said motor to be driven thereby during a predetermined amount of rotation of said motor, said pump dispensing a measured amount of fluid during said predetermined amount of rotation,
unijunction oscillator means coupled to said controlled rectifier means for generating a series of pulses, each of said pulses triggering said controlled rectifier means into conduction to initiate said predetermined amount of rotation of said motor, said pulses occurring at predetermined equal intervals of time, said interval between pulses including the time required forsaid motor to complete said predetermined amount of rotation, whereby dispensing of fluid by said pump is initiated at predetermined equal intervals of time irrespective of the time required for said motor to complete said predetermined amount of rotation, and
means for de-energizing said motor at the end of said predetermined amount of rotation.
2. The apparatus of claim l'whe rein said-means for de-energizing said motor comprises a switch connected across said controlled rectifier means forconducting current around said controlled rectifier means and to said motor when said switch is actuated, and a cam associated with said motor for momentarily actuating said switch at the end of said predetermined amountv of rotation of said motor, whereby at the end of said predetermined amount of rotation said controlled rectifier means is rendered receptive to the next pulse from said oscillator means.
. References Cited UNITED STATES PATENTS 2,917,751 12/1959 Fry et a1. 3-1 2,351,828. 6/1944 Marsh 103--25 2,962,610 11/1960 Husband 307141.4 3,048,708 8/1962 Rauer 307293 3,162,772 12/1964 Smith' 307293 3,333,175 7/1967 Kly'ce 307-293 3,073,244 1/1963 Elliot et a1. 103-25 3,262,042 7/1966 Amos 318487 3,287,721 11/1966 Baehr 128-214 3,364,410 l/l968 Foreman 318-484 3,309,602 3/1967 Euvino 'et al 307133 0 WILLIAM L. FREEH, Primary Examiner Us. c1. X.R.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US63496467A | 1967-05-01 | 1967-05-01 |
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US3498228A true US3498228A (en) | 1970-03-03 |
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US634964A Expired - Lifetime US3498228A (en) | 1967-05-01 | 1967-05-01 | Portable infusion pump |
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Cited By (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3584766A (en) * | 1969-12-10 | 1971-06-15 | Charles M Hart | Spray dispenser having a capacitor discharge timer |
DE2037946A1 (en) * | 1970-04-14 | 1971-10-28 | Ivac Corporation, San Diego, Calif. (V.StA.) | Flow control device |
US3716756A (en) * | 1972-03-03 | 1973-02-13 | R K Electric Co Inc | Recycle prevention control circuit |
US3731679A (en) * | 1970-10-19 | 1973-05-08 | Sherwood Medical Ind Inc | Infusion system |
US3771694A (en) * | 1972-07-07 | 1973-11-13 | A Kaminski | Infusion pump |
DE2651962A1 (en) * | 1976-11-15 | 1978-05-18 | Siemens Ag | Miniature peristaltic pump for infusing liq., esp. insulin - has motor driven rollers and tube held in contact by spring pressure |
DE3138478A1 (en) * | 1980-09-27 | 1982-05-19 | Terumo Corp., Tokyo | METHOD AND DEVICE FOR INTERMITTENTLY DISPENSING A MEDICAL SOLUTION IN SMALL CAN |
US4524311A (en) * | 1982-11-12 | 1985-06-18 | Mitsubishi Denki Kabushiki Kaisha | Control for pumping devices used in vehicles |
WO1986000233A1 (en) * | 1984-06-29 | 1986-01-16 | Linkie Daniel M | Apparatus and methodology for pulsed administration of growth promoting agents |
US4850972A (en) * | 1987-01-16 | 1989-07-25 | Pacesetter Infusion, Ltd. | Progammable multiple pump medication infusion system with printer |
US4884013A (en) * | 1988-01-15 | 1989-11-28 | Sherwood Medical Company | Motor unit for a fluid pump and method of operation |
US4953763A (en) * | 1988-11-04 | 1990-09-04 | Kierum Chandler T | Animal scent dispensing apparatus |
US6139535A (en) * | 1999-05-27 | 2000-10-31 | Situs Corporation | Method and apparatus for placement and activation of a medical device within a body cavity |
US6171298B1 (en) | 1996-05-03 | 2001-01-09 | Situs Corporation | Intravesical infuser |
US6183461B1 (en) | 1998-03-11 | 2001-02-06 | Situs Corporation | Method for delivering a medication |
US20010041869A1 (en) * | 2000-03-23 | 2001-11-15 | Causey James D. | Control tabs for infusion devices and methods of using the same |
US6517009B2 (en) | 1997-12-25 | 2003-02-11 | Gotit Ltd. | Automatic spray dispenser |
US20040013532A1 (en) * | 2000-07-12 | 2004-01-22 | Kurt Solgaard | Method for controlling the electric motor of a metering pump |
US6752787B1 (en) * | 1999-06-08 | 2004-06-22 | Medtronic Minimed, Inc., | Cost-sensitive application infusion device |
US8663538B2 (en) | 2009-02-12 | 2014-03-04 | Picolife Technologies, Llc | Method of making a membrane for use with a flow control system for a micropump |
US8771229B2 (en) | 2011-12-01 | 2014-07-08 | Picolife Technologies, Llc | Cartridge system for delivery of medicament |
US8790307B2 (en) | 2011-12-01 | 2014-07-29 | Picolife Technologies, Llc | Drug delivery device and methods therefor |
US9883834B2 (en) | 2012-04-16 | 2018-02-06 | Farid Amirouche | Medication delivery device with multi-reservoir cartridge system and related methods of use |
US10130759B2 (en) | 2012-03-09 | 2018-11-20 | Picolife Technologies, Llc | Multi-ported drug delivery device having multi-reservoir cartridge system |
US10245420B2 (en) | 2012-06-26 | 2019-04-02 | PicoLife Technologies | Medicament distribution systems and related methods of use |
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US2917751A (en) * | 1956-04-10 | 1959-12-22 | Interscience Res Corp | Mechanical heart |
US2962610A (en) * | 1960-02-08 | 1960-11-29 | Reed J Husband | Repeat cycle timer |
US3048708A (en) * | 1958-06-25 | 1962-08-07 | Itt | Pulse timing control circuit |
US3073244A (en) * | 1960-06-29 | 1963-01-15 | Cutler Hammer Inc | Condition responsive fluid flow monitoring and control system |
US3162772A (en) * | 1961-06-20 | 1964-12-22 | Jr Charles E Smith | Electronic sequence timer |
US3262042A (en) * | 1961-10-06 | 1966-07-19 | Lucas Industries Ltd | Electrical operating circuits for vehicle windscreen wipers |
US3287721A (en) * | 1964-07-03 | 1966-11-22 | Sigmamotor Inc | Intravenous alarm supply monitor |
US3309602A (en) * | 1963-07-18 | 1967-03-14 | Sperry Rand Corp | Current controllers |
US3333175A (en) * | 1964-06-30 | 1967-07-25 | Regent Controls Inc | Machine tool timer |
US3364410A (en) * | 1965-01-07 | 1968-01-16 | Motorola Inc | Windshield wiper |
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1967
- 1967-05-01 US US634964A patent/US3498228A/en not_active Expired - Lifetime
Patent Citations (11)
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US2351828A (en) * | 1942-01-08 | 1944-06-20 | G L Meyers | Surgical pump |
US2917751A (en) * | 1956-04-10 | 1959-12-22 | Interscience Res Corp | Mechanical heart |
US3048708A (en) * | 1958-06-25 | 1962-08-07 | Itt | Pulse timing control circuit |
US2962610A (en) * | 1960-02-08 | 1960-11-29 | Reed J Husband | Repeat cycle timer |
US3073244A (en) * | 1960-06-29 | 1963-01-15 | Cutler Hammer Inc | Condition responsive fluid flow monitoring and control system |
US3162772A (en) * | 1961-06-20 | 1964-12-22 | Jr Charles E Smith | Electronic sequence timer |
US3262042A (en) * | 1961-10-06 | 1966-07-19 | Lucas Industries Ltd | Electrical operating circuits for vehicle windscreen wipers |
US3309602A (en) * | 1963-07-18 | 1967-03-14 | Sperry Rand Corp | Current controllers |
US3333175A (en) * | 1964-06-30 | 1967-07-25 | Regent Controls Inc | Machine tool timer |
US3287721A (en) * | 1964-07-03 | 1966-11-22 | Sigmamotor Inc | Intravenous alarm supply monitor |
US3364410A (en) * | 1965-01-07 | 1968-01-16 | Motorola Inc | Windshield wiper |
Cited By (33)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3584766A (en) * | 1969-12-10 | 1971-06-15 | Charles M Hart | Spray dispenser having a capacitor discharge timer |
DE2037946A1 (en) * | 1970-04-14 | 1971-10-28 | Ivac Corporation, San Diego, Calif. (V.StA.) | Flow control device |
US3731679A (en) * | 1970-10-19 | 1973-05-08 | Sherwood Medical Ind Inc | Infusion system |
US3716756A (en) * | 1972-03-03 | 1973-02-13 | R K Electric Co Inc | Recycle prevention control circuit |
US3771694A (en) * | 1972-07-07 | 1973-11-13 | A Kaminski | Infusion pump |
DE2651962A1 (en) * | 1976-11-15 | 1978-05-18 | Siemens Ag | Miniature peristaltic pump for infusing liq., esp. insulin - has motor driven rollers and tube held in contact by spring pressure |
DE3138478A1 (en) * | 1980-09-27 | 1982-05-19 | Terumo Corp., Tokyo | METHOD AND DEVICE FOR INTERMITTENTLY DISPENSING A MEDICAL SOLUTION IN SMALL CAN |
US4524311A (en) * | 1982-11-12 | 1985-06-18 | Mitsubishi Denki Kabushiki Kaisha | Control for pumping devices used in vehicles |
WO1986000233A1 (en) * | 1984-06-29 | 1986-01-16 | Linkie Daniel M | Apparatus and methodology for pulsed administration of growth promoting agents |
US4747825A (en) * | 1984-06-29 | 1988-05-31 | Ferring Laboratories, Inc. | Apparatus and methodology for pulsed administration of growth promoting agents |
US4850972A (en) * | 1987-01-16 | 1989-07-25 | Pacesetter Infusion, Ltd. | Progammable multiple pump medication infusion system with printer |
US4884013A (en) * | 1988-01-15 | 1989-11-28 | Sherwood Medical Company | Motor unit for a fluid pump and method of operation |
US4953763A (en) * | 1988-11-04 | 1990-09-04 | Kierum Chandler T | Animal scent dispensing apparatus |
US6171298B1 (en) | 1996-05-03 | 2001-01-09 | Situs Corporation | Intravesical infuser |
US6517009B2 (en) | 1997-12-25 | 2003-02-11 | Gotit Ltd. | Automatic spray dispenser |
US6183461B1 (en) | 1998-03-11 | 2001-02-06 | Situs Corporation | Method for delivering a medication |
US6139535A (en) * | 1999-05-27 | 2000-10-31 | Situs Corporation | Method and apparatus for placement and activation of a medical device within a body cavity |
US6752787B1 (en) * | 1999-06-08 | 2004-06-22 | Medtronic Minimed, Inc., | Cost-sensitive application infusion device |
US20010041869A1 (en) * | 2000-03-23 | 2001-11-15 | Causey James D. | Control tabs for infusion devices and methods of using the same |
US20070100283A1 (en) * | 2000-03-23 | 2007-05-03 | Minimed Inc. | Control tabs for infusion devices and methods of using the same |
US20100160861A1 (en) * | 2000-03-23 | 2010-06-24 | Medtronic Minimed, Inc. | Control Tabs for Infusion Devices and Methods of Using the Same |
US8613726B2 (en) | 2000-03-23 | 2013-12-24 | Medtronic Minimed, Inc. | Control tabs for infusion devices and methods of using the same |
US7118347B2 (en) * | 2000-07-12 | 2006-10-10 | Grundfos A/S | Method for activating an electric motor and a metering pump by supplying predetermined pulse intervals to supply predetermined fluid quantities |
US20040013532A1 (en) * | 2000-07-12 | 2004-01-22 | Kurt Solgaard | Method for controlling the electric motor of a metering pump |
US8807169B2 (en) | 2009-02-12 | 2014-08-19 | Picolife Technologies, Llc | Flow control system for a micropump |
US8663538B2 (en) | 2009-02-12 | 2014-03-04 | Picolife Technologies, Llc | Method of making a membrane for use with a flow control system for a micropump |
US8771229B2 (en) | 2011-12-01 | 2014-07-08 | Picolife Technologies, Llc | Cartridge system for delivery of medicament |
US8790307B2 (en) | 2011-12-01 | 2014-07-29 | Picolife Technologies, Llc | Drug delivery device and methods therefor |
US9993592B2 (en) | 2011-12-01 | 2018-06-12 | Picolife Technologies, Llc | Cartridge system for delivery of medicament |
US10213549B2 (en) | 2011-12-01 | 2019-02-26 | Picolife Technologies, Llc | Drug delivery device and methods therefor |
US10130759B2 (en) | 2012-03-09 | 2018-11-20 | Picolife Technologies, Llc | Multi-ported drug delivery device having multi-reservoir cartridge system |
US9883834B2 (en) | 2012-04-16 | 2018-02-06 | Farid Amirouche | Medication delivery device with multi-reservoir cartridge system and related methods of use |
US10245420B2 (en) | 2012-06-26 | 2019-04-02 | PicoLife Technologies | Medicament distribution systems and related methods of use |
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