New! View global litigation for patent families

US3457922A - Stereotaxic surgical instrument and method - Google Patents

Stereotaxic surgical instrument and method Download PDF

Info

Publication number
US3457922A
US3457922A US3457922DA US3457922A US 3457922 A US3457922 A US 3457922A US 3457922D A US3457922D A US 3457922DA US 3457922 A US3457922 A US 3457922A
Authority
US
Grant status
Grant
Patent type
Prior art keywords
ray
assembly
skull
fig
instrument
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
Inventor
Charles D Ray
Original Assignee
Charles D Ray
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Grant date

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/10Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges for stereotaxic surgery, e.g. frame-based stereotaxis
    • A61B90/11Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges for stereotaxic surgery, e.g. frame-based stereotaxis with guides for needles or instruments, e.g. arcuate slides or ball joints

Description

July 29, 1969 c. D. RAY

STEREOTAXIC SURGICAL INSTRUMENT AND METHOD 4 Sheets-Sheet 1 Filed Dec. 13, 1966 INVENTOR;

CHARLES RAY TTQ 557.

July 29, 1969 c. 0. RAY

STEREOTAXIC SURGICAL INSTRUMENT AND METHOD 4 Sheets-Sheet 2 Filed Dec.

35 INVENTOR: CHARLES D. RAY

July 29, 1969 v c. D. RAY 3,457,922

v ESTEREOTAXIC SURGICAL INSTRUMENT AND METHOD Filed Dec. 13, 1966 4 Sheets-Sheet 5 QINVENTOR:

CHARLES 0. RAY

y 29, 1969 c. o. RAY 3,457,922

STEREOTAXIC SURGICAL INSTRUMENT AND METHOD Filed Dec. 13. 1966 4 Sheets-Sheet.4

INVENTOR: CHARLES D. RAY

United States Patent M 3,457,922 STEREOTAXIC SURGICAL INSTRUMENT AND METHOD Charles D. Ray, 601 N. Broadway, Baltimore, Md. 21205 Filed Dec. 13, 1966, Ser. No. 601,445 Int. Cl. A61b 17/00 US. Cl. 128303 2 Claims ABSTRACT OF THE DISCLOSURE A stereotaxic surgical instrument having a 'base element of low profile adapted to be secured to the skull by a rapid process of nailing including an arm having one end adjustably securable to the base including a surgical guiding means pivotally secured adjacent the opposite end thereof for guiding a surgical instrument in which the surgical guide means is provided with an aperture therethrough extending in a general direction perpendicular to the surface of the skull wherein the axis of the aperture through the pivotable means may be oriented from various adjusted locations with one or more surgical targets within the skull cavity without relocating the base element on the skull.

The present invention relates to a new instrument and method of stereotaxic surgery and implantation of brain electrodes or probes.

In the past, several stereotaxic techniques and instruments have been developed for study and treatment of certain disorders of the brain and associated structures within the head. For such uses the instruments must be capable of permitting accurate placement of various diagnostic and surgical devices. Most such instruments are awkward, expensive and bulky. Further, their use has been complicated by difficulty in attachment, the presence of index scales, complex protractors or rectangular measuring systems requiring careful manipulation and the use of certain correction factors found to vary in many patients. Even with the simpler instruments more recently developed, holes up to one inch in diameter must be placed through the scalp and skull in order to attach the instrument base. Specific anatomical structures are localized within the brain by the X-ray visualization of air or certain organic iodine compounds placed into the major fluid cavities of the brain, the ventricular system. From these visualized landmarks the sites of proposed electrode or probe implantations are determined by measurement and calculation. Such measurements and calculations are generally diflicult or tedious not only because of the complexity of the instruments, but also because of distortions and enlargements produced by the X-ray beam.

Further, while such instruments are capable of accurate placement of brain devices or probes for temporary or acute use, they are not generally designed nor usable for the placement of devices to be left in for a prolonged period. Stereotaxic instruments generally permit implantation to occur from or through only limited areas of the head in order to avoid certain critical srtuctures of the brain.

It is a primary object of this invention to provide an improved and simplified positioning instrument for implantation of brain electrodes, probes and surgical devices.

Another object is to provide precise and convenient universal adjustment of the instrument.

Still another object of the present invention is to provide a rapid, simple and firm attachment of the supporting base of the instrument to the skull. This same is performed without the need for holes to be placed through the scalp Patented July 29, 1969 and bone. In that external contours of skulls show variation among patients, the supporting base is adaptable to those contours of all human skulls.

A further object of the present invention is to provide a freely movable locating-guiding assembly that is remotely attached to the supporting base which is firmly attached to the skull.

Still another object of the present invention is to provide accurate positioning of the implement prior to drilling of the bone, opening the head or otherwise penetrating the skull and brain.

A still further object of the present invention is to provide an instrument for implantation of a brain electrode or probe which permits the point of entry and path into the brain to be adjusted prior to implantation thus avoiding engagement with critical areas thereof. By the use of X-rays during positioning, the path of the drill hole is made accurately and the end of the electrode or probe can thus be positioned in a desired location. In that the locator assembly lies in the X-ray beam it is therefore subject to the same circumstances as the skull; thus no special correction for X-ray distortion or magnification is needed.

Ancillary to the preceding object, it is a further object of the present invention to provide a probe anchoring device which may be firmly and accurately placed in the skull. Said anchoring device can be guided through the locating-guiding assembly of the stereotaxic instrument and driven into place utilizing a special hammer developed for this use.

The above and other objects and advantages of the present invention will become apparent in the following descriptions and drawings, wherein:

FIG. 1 is a side perspective view of the instrument constructed according to and embodying the present invention;

FIG. 2 is a top plan fragmentary view of the attachment device;

FIG. 3 is an enlarged sectional view taken along line 33 in FIG. 2;

FIG. 4 is an enlarged side fragmentary view of the protra-ctor-pointer assembly partly in section and partly in elevation;

FIG. 5 is a sectional view taken along line 5-5 in FIG. 4;

FIG. 6 is a top plan fragmentary view of the protractor-pointer assembly;

FIG. 7 is a diagrammatic front elevation of the instrument applied to a skull;

FIG. 8 is a diagrammatic right-hand side elevation of the instrument shown in FIG. 7;

FIG. 9 is an enlarged fragmentary sectional view of the protractor-pointer assembly in place on a skull;

FIG. 10 is a fragmentary sectional view as shown in FIG. 9, the scalp and skull shown being drilled;

FIG. 11 is a fragmentary sectional view as shown in FIG. 9, a sliding weight hammer shown in use to drive a pin into the skull;

FIG. ll-A is an enlarged sectional view of the driver tip and pin; and

FIG. 12 is an enlarged fragmentary sectional view showing a brain probe assembly attached to the pin, wherewith an electrical connector assembly and an enlarged sectional view of the brain probe are also shown; and

FIG. 12-A is a sectional view taken along the line 12A of FIG. 12.

Referring now to the drawings, particularly FIGS. 1 and 2, reference numeral 10 generally designates the present instrument which includes a tripod base 11 having three foot-plate assemblies 12, and a centrally located,

freely movable, compressible ball 13 that can be locked in any position by a clamping ring 14 having a surface complementary thereto. Through the threaded center of this ball 13 is placed a bolt 15 which may be tightened against an extension arm 16 thus holding same in some desired position. On one side of the extension arm 16 is a removable pointer assembly 17 including a base portion 36, an outwardly extended portion 36' and a point 36". Near the distal end of the extension arm 16 is a spherically surfaced concavity which defines a coupling socket into which is placed a second freely movable, compressible ball 18. This ball 18 and the central ball 13 are formed of a steam autoclavable, X-ray transparent plastic such as polycarbonate or polyphenylene oxide or the like. Said distal ball 18 rotates in a complementary surface of the outer end of the extension arm 16 and is locked in position by tightening the set screw 19 pinching the ball between the confronting faces of the jaw members 16' and 16". Threaded into the axial bore of the distal ball 18 is a removable hollow guide bolt 20 onto which is shown attached a spherical protactor assembly 21. The upper surface 34 of this protractor 34, in near contact with the tip of the pointer 36", is accurately engraved to indicate angular changes from position 22 to a new position 23 (see FIG. 1).

Referring to FIG. 3 it can be seen that the foot-plate assembly 12 consists of a freely movable, drilled singleball bearing 24 whose race 25 has been pressed into the tripod base 11. Pressed into the ball 24 is a foot-plate 26. Through the center of same is placed a removable cranial nail 27 having a threaded upper end 27 and a pointed lower end 27". The central ball 13 is clamped in desired position by the clamping ring 14 by the three set screws 28 placed equidistant around said clamping ring 14. The central bolt 15 compresses a thrust washer 29 against the extension arm 16 and against a spacer 30 thence against the central ball 13.

Referring now to FIGURES 4 through 6, reference numeral 17 refers generally to the pointer assembly and reference numeral 21 refers generally to the spherical protractor assembly. The demountable protractor assembly 21 is provided with a shaft 31 made of X-ray translucent aluminum down the center of same is poured a lead core 33 being opaque to X-rays. Said shaft 31 is held into place on the bolt 20 of the distal ball 18 by a captive nut 32. The protractor proper 34 is firmly screwed to the shaft 31 and is provided with outer curved surface. With 34 the curved outer surface is provided with grid grooves or lines 34", the distal hall 18 in a position with its axial shaft 31 perpendicular to the plane of the extension arm, the point C on the surface of the protractor 34 indicates a central location for the protractor assembly or neutral zero position as shown in FIGS. 4 and 6. Angular displacements of the ball about its axis from this neutral zero position are indicated by the grid grooves or lines as previously described. The said grid grooves or lines are placed each 2 degrees with heavier grooves at 10 degree spacing. The member 34 of the protractor assembly is made of an X-ray transparent plastic similar to that of the central and distal balls 13 and 18. All grid grooves are filled with a cured mixture of white lead and epoxy plastic. These grooves are thereby X-ray opaque. The grooves, being established in reference to the center of rotation of the distal ball 18 exhibit a great circle curvature.

The pointer assembly 17 is demountable from the extension arm 16 by means of a captive screw 35 maintained to the pointer arm 36 by a permanently pressed on spacer 37. Two indexing pins 38 are permanently pressed into the pointer arm 36 base and mate into corresponding holes in the extension arm 16 thus establishing a temporary rigid attachment to same.

Referring now in particular to FIGS. 7 through 11, the operation of the instrument is as follows:

The instrument is placed upon the head 39 at a predetermined location and in turn each tripod foot-plate assembly 12 is anchored to the skull by the driving of a cranial nail 48 or screw or suitable holding element. The cranial nail 27 may be screwed into the end of the captive hammer 42 to be so driven. When firmly attached to the head, the tripod base 11 is rigid with respect to the skull. Set screws 28-and 19 and central bolt 15 are made slack so that the positioning of the extension arm 16 and the distal ball 18 is freely selectable for any point over the surface of the head 39. The protractor assembly 21 is attached into the guide bolt 20 within the distal ball 18 and made fast by tightening the captive nut 32 provided. The pointer assembly 17 is then attached to the extension arm 16 and made fast utilizing the captive screw 35 and indexing pins 38. A first approximation path 22 of the final desired path 23 to the brain target 40 is made and all set screws 19 and 28 are tightened such that no motions of the present instrument are now permitted save a sliding friction movement of the distal ball 18 and protractor assembly 21.

The major reference cross lines on the spherical surface of the protractor 34 are adjusted to lie exactly parallel and perpendicular to the front-to-back center line of the skull. Adequate X-ray contrast medium is instilled into the brain cavities or ventricles 41 and the proposed target site 40 is exactly determined based on requirements of the operative case.

A carefully positioned front-to-back, or anterior-posterior X-ray film is taken as shown diagrammatically in FIG. 7. In a similar manner same is performed for a lateral film as in FIG. 8. Close examination of said films will disclose the correct path 23 to be taken. A line is drawn upon the surface of the X-ray film extending from the target site outward through the center of the distal ball 18 and beyond thence through the protractor 34. The central lead core 33 of the protractor shaft 31 and individual lead-filled surface grooves 34" of the protractor 34 are clearly visible on the X-ray film as shown diagrammatically in FIG. 9, thus permitting an accurate angular correction to be determined for both anterior-posterior and lateral planes. The protractor assembly 21 and distal ball 18 alone are carefully moved so as to correspond to the desired path 23 to the brain target 40. Following this, recheck or confirmatory X-ray films may be taken in the two planes. The set screw 19 holding the distal ball 18 is now firmly tightened. No further movements of the instrument 10 relative to the head 39 may now be permitted. Both the pointer assembly 17 and protractor assembly 21 are now removed.

As is shown diagrammatically in FIG. 10, a drill is passed through the guide bolt 20 and thence penetrates scalp and bone of the head 39 in the desired path 23.

Referring now to FIG. 11, a captive hammer is generally referred to by the numeral 42 and comprises a shaft 43 onto one end at which is affixed a stop piece 44 having a threaded hole therein. On the opposite end of said shaft 43 is a grasping handle 45. A freely sliding weight 46 may thus be slid axially along the shaft 43 to engage or strike the stop piece 44 or the face of the handle 45. In the use described herein a pin inserter 47 is screwed into the stop piece 44. The distal end of this inserter 47 is so fabricated to pass into the core hold of the cranial pin 48 and thus made to drive said pin through the guide bolt 20 axially into the hold previously drilled into the skull 39. A diametric step 48' in the cranial pin 48 stops it at a desired length into the bone of the skull 39.

In that the cranial pin 48 has been positioned in the desired path 23 to the brain target 40, the entire instrument 10 may be moved elsewhere upon the head or removed entirely. If so desired the present instrument may be utilized for temporary or acute implantation so that no cranial pin 48 need be placed.

Referring now to FIG. 12 a brain probe is referred to generally by the numeral 50 and its mating electrical connector socket by the numeral 58. Said probe 50 consists of a central tube 51 having a hollow core 52 and around said tube are suitably cemented a plurality of fine wires 53 previously insulated for their entire length. Said wires 53 are attached to the end of a suitable electrical connector 55 comprising one of same for each wire used in the probe. This assembly is then encapsulated thus insulating the terminations between wires 53 and connectors 55. After fabrication of the probe device a suitable contact 56 is established at a singular, selected location .by removing the insulation from the wire at that point. Said probe 50 has been previously disclosed and is not presented as a part of the present invention.

The probe or other such device is maintained on the head for prolonged implantation thusly: onto the threaded end of the cranial pin 48 is screwed a retaining cup 49, into same is then placed the probe 50 or other such device. Same is held firmly in place and is prevented from movement by a locking ring 57 whose inner surfaces are suitably disposed to seal the probe 50 against the retaining cup 49. Said probe 50 is of sufficient length to reach the brain target 40. An electrical connector socket assembly 58 may be mated with the probe at such time as diagnostic studies are to be performed.

The captive hammer 42 is used both to drive and remove the cranial nails 27 and the cranial pins 48. Same may be implanted with or without the use of a pin inserter 47. A rapid sliding of the weight 46 transmits its force axially into or away from the implanted piece depending on the direction of slide and end struck.

It will be appreciated that there is herewith illustrated and described an instrument which may be easily attached to the skull, permitting exact determinations of paths to be taken for inmplantation of devices for temporary or prolonged study or treatment of selected targets within the brain utilizing landmarks determined by standard X-ray film.

Variations and modifications may be made without departing from the spirit of this presentation of a preferred embodiment of the present invention.

I claim:

1. A stereotaxic instrument for use with an X-ray machine to locate a target area within a skull cavity having a base adapted to be fixed to the skull and supporting thereon an adjustable pivot means including means for fixing the position of the pivot means relative to the base comprising in combination:

(a) an elongated arm having an end portion releasable fixedly to said pivot and longitudinally adjustable relative to said pivot, and means for locking the arm at selected positions;

(b) means on said arm positioned outwardly from said first pivot means for engaging a second pivot means, and means for fixing the position of the second pivot means relative to the arm;

(c) the second pivot means having a guideway associated therewith;

(d) an X-ray transparent removable protractor assembly including a stem constructed of X-ray trans parent material adapted to have one end slidably engageable and removable with the said guideway of the second pivotable member and a disk-like member fixed to the opposite end of the stem, the outer surface of the disk-like member being provided with grid lines of X-ray photographic material;

(e) an X-ray photographic material extending along said grid lines and along said stern;

(f) an opaque stationary pointer afiixed to the said arm and extending over the grid surface of the disk and in close proximity thereto; whereby the position of the pointer on the grid surface may be recorded on an X-ray picture along with the angle of the stem in its relation to the target area in the skull cavity.

2. A method of determining the direction and course of a brain probe toward a target area within a skull cavity, from outside the skull, in which an adjustable, fixable support including a fixed pointer is utilized to support a pivotable and fixable-holding member having a guideway associated therewith for a directional indicating means for indicating the path of the probe, wherein the directional indicator consists of an X-ray transparent removable protractor assembly including a stern constructed of X-ray transparent material having a photographic longitudinal line extending therealong adapted to have one end engagable with the guideway of the holding member and a disk-like member having an outer surface provided with grid lines thereon corresponding to the angle of the protractor relative to the center line thereof and fixed to the opposite end of the stem, wherein said grid lines are X-ray photographic, comprising the steps:

(a) securing the support to the skull;

(b) fixing the holder for the protractor assembly at a predetermined point over the outer surface of the skull;

(c) inserting the stem of the protractor assembly into the guideway of the holder;

(d) aligning the pointer with a predetermined pair of I intersecting grids;

(e) making an X-ray film of the entire assembly, showing both protractor and desired point within the skull cavity;

(f) extending the photographic line of the stern on the film to a point indicating the inward portion of the skull cavity;

(g) extending a line on the film through the pivot point of the protractor assembly holding means and the target area;

(h) determining the angle between the two lines extending outwardly from the holding means, noting the points where the lines extend through the grid marks as shown on the X-ray film;

(i) readjusting the protractor assembly by using the grid lines formed on the disk to represent the number of degrees between the inverging lines on the film;

(j) making a verification X-ray film;

(k) removing the protractor assembly from the holder guideway;

(l) inserting a drill tool within said guideway in the holder and drilling an opening in the skull along the axis of the said guideway of the holder;

(m) removing said drill and insreting a tool along the said guideway having a probe guide element detachably secured thereto, forcing the said probe guide element into said skull opening along the axis of the guideway, detaching said tool, inserting said probe and extending the same beyond the said probe guide element into the skull cavity and toward the target area.

References Cited UNITED STATES PATENTS 3,073,310 1/1963 Mocarski 128-303 3,357,431 12/1967 Newell 128303 L. W. TRAPP, Primary Examiner

US3457922A 1966-12-13 1966-12-13 Stereotaxic surgical instrument and method Expired - Lifetime US3457922A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US60144566 true 1966-12-13 1966-12-13

Publications (1)

Publication Number Publication Date
US3457922A true US3457922A (en) 1969-07-29

Family

ID=24407499

Family Applications (1)

Application Number Title Priority Date Filing Date
US3457922A Expired - Lifetime US3457922A (en) 1966-12-13 1966-12-13 Stereotaxic surgical instrument and method

Country Status (1)

Country Link
US (1) US3457922A (en)

Cited By (63)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4228799A (en) * 1977-09-28 1980-10-21 Anichkov Andrei D Method of guiding a stereotaxic instrument at an intracerebral space target point
US4230117A (en) * 1978-02-27 1980-10-28 Anichkov Andrei D Stereotaxic apparatus
US4579009A (en) * 1984-12-21 1986-04-01 Maplehurst Ova Transplants, Inc. Coupling for use with micromanipulator
US4592352A (en) * 1984-11-30 1986-06-03 Patil Arun A Computer-assisted tomography stereotactic system
WO1986007542A1 (en) * 1985-06-17 1986-12-31 Ghajar Jamshid B G Apparatus for guiding catheter into cerebral ventricle
EP0212213A1 (en) * 1985-07-16 1987-03-04 Thomas Jefferson University Cerebral catheterization apparatus
US4681103A (en) * 1985-03-11 1987-07-21 Diasonics, Inc. Ultrasound guided surgical instrument guide and method
US4840617A (en) * 1980-04-14 1989-06-20 Thomas Jefferson University Cerebral and lumbar perfusion catheterization apparatus for use in treating hypoxic/ischemic neurologic tissue
US4955891A (en) * 1985-07-02 1990-09-11 Ohio Medical Instrument Company, Inc. Method and apparatus for performing stereotactic surgery
US5116345A (en) * 1990-11-28 1992-05-26 Ohio Medical Instrument Co., Inc. Stereotactically implanting an intracranial device
US5163430A (en) * 1990-04-27 1992-11-17 Medco, Inc. Method and apparatus for performing stereotactic surgery
US5263956A (en) * 1992-03-04 1993-11-23 Neuro Navigational Corporation Ball joint for neurosurgery
US5403319A (en) * 1988-04-26 1995-04-04 Board Of Regents Of The University Of Washington Bone imobilization device
WO1995022297A1 (en) * 1994-02-18 1995-08-24 Implico B.V. Stereotactic pointing device
EP0729322A1 (en) * 1993-11-15 1996-09-04 D'Urso, Paul, Steven Surgical procedures
US5634929A (en) * 1993-04-16 1997-06-03 Oregon Neuro-Medical Technology, Inc. Apparatus for stereotactic radiosurgery and fractionated radiation therapy
WO1998036706A1 (en) * 1997-02-24 1998-08-27 Co.Don Gmbh Gesellschaft Für Molekulare Medizin Und Biotechnologie Set of surgical instruments
US5810712A (en) * 1996-09-27 1998-09-22 Ohio Medical Instrument Company, Inc. Surgical endoscope support and pivot
EP0832611A3 (en) * 1996-09-30 1998-09-30 Allen, George S. Biopsy guide
FR2782631A1 (en) * 1998-08-25 2000-03-03 Patrick Metais Human brain cell sampling point positioner for post mortem diagnosis of Alzheimer's disease has variable-angle positioning and guide rods
WO2000064354A3 (en) * 1999-04-26 2001-03-08 Scimed Life Systems Inc Apparatus and methods for guiding a needle
US6273896B1 (en) * 1998-04-21 2001-08-14 Neutar, Llc Removable frames for stereotactic localization
US20020010479A1 (en) * 2000-04-07 2002-01-24 Skakoon James G. Medical device introducer
US20030114862A1 (en) * 2001-12-14 2003-06-19 Chu Michael S.H. Methods and apparatus for guiding a needle
EP1351619A2 (en) * 2001-01-16 2003-10-15 Microdexterity Systems Inc. Surgical manipulator
US6689142B1 (en) 1999-04-26 2004-02-10 Scimed Life Systems, Inc. Apparatus and methods for guiding a needle
US6752812B1 (en) 1997-05-15 2004-06-22 Regent Of The University Of Minnesota Remote actuation of trajectory guide
WO2004058086A1 (en) * 2002-12-20 2004-07-15 Image-Guided Neurologics, Inc. Alignment device and method
US20040153083A1 (en) * 2003-01-31 2004-08-05 Howmedica Osteonics Corp. Universal alignment guide
US6782288B2 (en) 1998-10-08 2004-08-24 Regents Of The University Of Minnesota Method and apparatus for positioning a device in a body
US20050033315A1 (en) * 2003-08-01 2005-02-10 Hankins Carol A. Apparatus and method for guiding a medical device
US20050070920A1 (en) * 2003-09-25 2005-03-31 Image-Guided Neurologics, Inc. Ball and socket trajectory guide
WO2005044126A1 (en) * 2003-10-03 2005-05-19 Smith & Nephew, Inc. Surgical positioners
US6902569B2 (en) 2000-08-17 2005-06-07 Image-Guided Neurologics, Inc. Trajectory guide with instrument immobilizer
US20060030944A1 (en) * 2004-01-14 2006-02-09 Haines Timothy G Methods and apparatus for enhanced retention of prosthetic implants
US20060064105A1 (en) * 2004-09-09 2006-03-23 Howmedica Osteonics Corp. Navigated drill guided resection block
US20070096863A1 (en) * 2005-10-31 2007-05-03 Benito Valencia Avila System for protecting circuitry in high-temperature environments
US7229451B2 (en) * 2001-04-17 2007-06-12 Integra Ohio, Inc. Skull clamp with load distribution indicators
US7237556B2 (en) 2002-02-11 2007-07-03 Smith & Nephew, Inc. Image-guided fracture reduction
US20070250078A1 (en) * 2001-01-16 2007-10-25 Microdexterity Systems, Inc. Surgical manipulator
US20080154270A1 (en) * 2001-03-05 2008-06-26 Haines Timothy G Methods and apparatus for knee arthroplasty
US7477926B2 (en) 2004-03-31 2009-01-13 Smith & Nephew, Inc. Methods and apparatuses for providing a reference array input device
US7497863B2 (en) 2004-12-04 2009-03-03 Medtronic, Inc. Instrument guiding stage apparatus and method for using same
US7547307B2 (en) 2001-02-27 2009-06-16 Smith & Nephew, Inc. Computer assisted knee arthroplasty instrumentation, systems, and processes
US7559935B2 (en) 2003-02-20 2009-07-14 Medtronic, Inc. Target depth locators for trajectory guide for introducing an instrument
US7658879B2 (en) 2003-02-20 2010-02-09 Medtronic, Inc. Trajectory guide with angled or patterned guide lumens or height adjustment
US7704260B2 (en) 2002-09-17 2010-04-27 Medtronic, Inc. Low profile instrument immobilizer
US7744606B2 (en) 2004-12-04 2010-06-29 Medtronic, Inc. Multi-lumen instrument guide
US7764985B2 (en) 2003-10-20 2010-07-27 Smith & Nephew, Inc. Surgical navigation system component fault interfaces and related processes
US7794467B2 (en) 2003-11-14 2010-09-14 Smith & Nephew, Inc. Adjustable surgical cutting systems
WO2010112013A1 (en) * 2009-04-01 2010-10-07 Charité - Universitaetsmedizin Berlin Device for guiding a ventricle catheter during implantation
US7967822B2 (en) 1994-09-02 2011-06-28 Hudson Surgical Design, Inc. Methods and apparatus for orthopedic implants
US8021368B2 (en) 2004-01-14 2011-09-20 Hudson Surgical Design, Inc. Methods and apparatus for improved cutting tools for resection
US8109942B2 (en) 2004-04-21 2012-02-07 Smith & Nephew, Inc. Computer-aided methods, systems, and apparatuses for shoulder arthroplasty
US8114083B2 (en) 2004-01-14 2012-02-14 Hudson Surgical Design, Inc. Methods and apparatus for improved drilling and milling tools for resection
US8177788B2 (en) 2005-02-22 2012-05-15 Smith & Nephew, Inc. In-line milling system
US20120298820A1 (en) * 2011-05-25 2012-11-29 Spiros Manolidis Surgical tool holder
US8603095B2 (en) 1994-09-02 2013-12-10 Puget Bio Ventures LLC Apparatuses for femoral and tibial resection
US8740906B2 (en) 2004-01-14 2014-06-03 Hudson Surgical Design, Inc. Method and apparatus for wireplasty bone resection
US20140277199A1 (en) * 2013-03-15 2014-09-18 Kyphon Sarl Surgical tool holder
US20150018835A1 (en) * 2012-01-26 2015-01-15 Smith & Nephew, Inc. Implant fixation member holder
WO2015032498A1 (en) * 2013-09-04 2015-03-12 Isys Medizintechnik Gmbh Device for attaching medical target devices and the like
US9707049B1 (en) * 2016-12-22 2017-07-18 The Florida International University Board Of Trustees Stereotactic device for implantation of permanent implants into a rodent brain

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3073310A (en) * 1957-08-05 1963-01-15 Zenon R Mocarski Surgical instrument positioning device
US3357431A (en) * 1965-03-03 1967-12-12 Allen & Hanburys Ltd Neurosurgical apparatus

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3073310A (en) * 1957-08-05 1963-01-15 Zenon R Mocarski Surgical instrument positioning device
US3357431A (en) * 1965-03-03 1967-12-12 Allen & Hanburys Ltd Neurosurgical apparatus

Cited By (114)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4228799A (en) * 1977-09-28 1980-10-21 Anichkov Andrei D Method of guiding a stereotaxic instrument at an intracerebral space target point
US4230117A (en) * 1978-02-27 1980-10-28 Anichkov Andrei D Stereotaxic apparatus
US4840617A (en) * 1980-04-14 1989-06-20 Thomas Jefferson University Cerebral and lumbar perfusion catheterization apparatus for use in treating hypoxic/ischemic neurologic tissue
US4592352A (en) * 1984-11-30 1986-06-03 Patil Arun A Computer-assisted tomography stereotactic system
US4579009A (en) * 1984-12-21 1986-04-01 Maplehurst Ova Transplants, Inc. Coupling for use with micromanipulator
US4681103A (en) * 1985-03-11 1987-07-21 Diasonics, Inc. Ultrasound guided surgical instrument guide and method
WO1986007542A1 (en) * 1985-06-17 1986-12-31 Ghajar Jamshid B G Apparatus for guiding catheter into cerebral ventricle
US4955891A (en) * 1985-07-02 1990-09-11 Ohio Medical Instrument Company, Inc. Method and apparatus for performing stereotactic surgery
EP0212213A1 (en) * 1985-07-16 1987-03-04 Thomas Jefferson University Cerebral catheterization apparatus
US5403319A (en) * 1988-04-26 1995-04-04 Board Of Regents Of The University Of Washington Bone imobilization device
US5571110A (en) * 1988-04-26 1996-11-05 Board Of Regents Of The University Of Washington Orthopedic saw guide for use in a robot-aided system for surgery
US5163430A (en) * 1990-04-27 1992-11-17 Medco, Inc. Method and apparatus for performing stereotactic surgery
US5116345A (en) * 1990-11-28 1992-05-26 Ohio Medical Instrument Co., Inc. Stereotactically implanting an intracranial device
US5263956A (en) * 1992-03-04 1993-11-23 Neuro Navigational Corporation Ball joint for neurosurgery
US5634929A (en) * 1993-04-16 1997-06-03 Oregon Neuro-Medical Technology, Inc. Apparatus for stereotactic radiosurgery and fractionated radiation therapy
EP0729322A4 (en) * 1993-11-15 1999-06-16 Urso Paul Steven D Surgical procedures
EP0729322A1 (en) * 1993-11-15 1996-09-04 D'Urso, Paul, Steven Surgical procedures
US5776143A (en) * 1994-02-18 1998-07-07 Implico B.V. Stereostatic pointing device
WO1995022297A1 (en) * 1994-02-18 1995-08-24 Implico B.V. Stereotactic pointing device
US8603095B2 (en) 1994-09-02 2013-12-10 Puget Bio Ventures LLC Apparatuses for femoral and tibial resection
US7967822B2 (en) 1994-09-02 2011-06-28 Hudson Surgical Design, Inc. Methods and apparatus for orthopedic implants
US9066804B2 (en) 1994-09-02 2015-06-30 Puget Bioventures Llc Method and apparatus for femoral and tibial resection
US5810712A (en) * 1996-09-27 1998-09-22 Ohio Medical Instrument Company, Inc. Surgical endoscope support and pivot
EP0832611A3 (en) * 1996-09-30 1998-09-30 Allen, George S. Biopsy guide
US5984930A (en) * 1996-09-30 1999-11-16 George S. Allen Biopsy guide
WO1998036706A1 (en) * 1997-02-24 1998-08-27 Co.Don Gmbh Gesellschaft Für Molekulare Medizin Und Biotechnologie Set of surgical instruments
US6752812B1 (en) 1997-05-15 2004-06-22 Regent Of The University Of Minnesota Remote actuation of trajectory guide
US6273896B1 (en) * 1998-04-21 2001-08-14 Neutar, Llc Removable frames for stereotactic localization
FR2782631A1 (en) * 1998-08-25 2000-03-03 Patrick Metais Human brain cell sampling point positioner for post mortem diagnosis of Alzheimer's disease has variable-angle positioning and guide rods
US6782288B2 (en) 1998-10-08 2004-08-24 Regents Of The University Of Minnesota Method and apparatus for positioning a device in a body
WO2000064354A3 (en) * 1999-04-26 2001-03-08 Scimed Life Systems Inc Apparatus and methods for guiding a needle
US20070203455A1 (en) * 1999-04-26 2007-08-30 Boston Scientific Scimed, Inc. Apparatus and methods for guiding a needle
US7766878B2 (en) 1999-04-26 2010-08-03 Boston Scientific Scimed, Inc. Entry needle and related method of use
US6689142B1 (en) 1999-04-26 2004-02-10 Scimed Life Systems, Inc. Apparatus and methods for guiding a needle
US7204826B2 (en) 1999-04-26 2007-04-17 Boston Scientific Scimed, Inc. Apparatus and methods for guiding a needle
WO2001076498A3 (en) * 2000-04-07 2002-04-18 Image Guided Neurologics Inc Deep organ access device and method
US7660621B2 (en) 2000-04-07 2010-02-09 Medtronic, Inc. Medical device introducer
US8845656B2 (en) 2000-04-07 2014-09-30 Medtronic, Inc. Device for immobilizing a primary instrument and method therefor
US8911452B2 (en) 2000-04-07 2014-12-16 Medtronic, Inc. Device for immobilizing a primary instrument and method therefor
US7235084B2 (en) 2000-04-07 2007-06-26 Image-Guided Neurologics, Inc. Deep organ access device and method
US7815651B2 (en) 2000-04-07 2010-10-19 Medtronic, Inc. Device for immobilizing a primary instrument and method therefor
US7857820B2 (en) 2000-04-07 2010-12-28 Medtronic, Inc. Sheath assembly for an access device and method therefor
US7204840B2 (en) 2000-04-07 2007-04-17 Image-Guided Neurologics, Inc. Deep organ access device and method
US7833231B2 (en) 2000-04-07 2010-11-16 Medtronic, Inc. Device for immobilizing a primary instrument and method therefor
US20020010479A1 (en) * 2000-04-07 2002-01-24 Skakoon James G. Medical device introducer
US7828809B2 (en) 2000-04-07 2010-11-09 Medtronic, Inc. Device for immobilizing a primary instrument and method therefor
US7637915B2 (en) 2000-08-17 2009-12-29 Medtronic, Inc. Trajectory guide with instrument immobilizer
US6902569B2 (en) 2000-08-17 2005-06-07 Image-Guided Neurologics, Inc. Trajectory guide with instrument immobilizer
US8192445B2 (en) 2000-08-17 2012-06-05 Medtronic, Inc. Trajectory guide with instrument immobilizer
US7892243B2 (en) 2001-01-16 2011-02-22 Microdexterity Systems, Inc. Surgical manipulator
EP1351619A2 (en) * 2001-01-16 2003-10-15 Microdexterity Systems Inc. Surgical manipulator
US20070250078A1 (en) * 2001-01-16 2007-10-25 Microdexterity Systems, Inc. Surgical manipulator
EP1351619A4 (en) * 2001-01-16 2011-01-05 Microdexterity Systems Inc Surgical manipulator
US7547307B2 (en) 2001-02-27 2009-06-16 Smith & Nephew, Inc. Computer assisted knee arthroplasty instrumentation, systems, and processes
US8062377B2 (en) 2001-03-05 2011-11-22 Hudson Surgical Design, Inc. Methods and apparatus for knee arthroplasty
US9421022B2 (en) 2001-03-05 2016-08-23 Puget Bioventures Llc Method and apparatus for total knee arthroplasty
US9192391B2 (en) 2001-03-05 2015-11-24 Puget Bioventures Llc Method for minimally invasive total knee arthroplasty
US20080154270A1 (en) * 2001-03-05 2008-06-26 Haines Timothy G Methods and apparatus for knee arthroplasty
US7935151B2 (en) 2001-03-05 2011-05-03 Hudson Surgical Design, Inc. Femoral prosthetic implant
US8088167B2 (en) 2001-03-05 2012-01-03 Hudson Surgical Design, Inc. Femoral prosthetic implant
US8430932B2 (en) 2001-03-05 2013-04-30 Puget Bio Ventures LLC Femoral prosthetic implant
US7229451B2 (en) * 2001-04-17 2007-06-12 Integra Ohio, Inc. Skull clamp with load distribution indicators
US8057487B2 (en) * 2001-12-14 2011-11-15 Boston Scientific Scimed, Inc. Methods and apparatus for guiding a needle
US7169155B2 (en) 2001-12-14 2007-01-30 Scimed Life Systems, Inc. Methods and apparatus for guiding a needle
US20030114862A1 (en) * 2001-12-14 2003-06-19 Chu Michael S.H. Methods and apparatus for guiding a needle
US20070135708A1 (en) * 2001-12-14 2007-06-14 Boston Scientific Scimed, Inc. Methods and apparatus for guiding a needle
US7237556B2 (en) 2002-02-11 2007-07-03 Smith & Nephew, Inc. Image-guided fracture reduction
US7704260B2 (en) 2002-09-17 2010-04-27 Medtronic, Inc. Low profile instrument immobilizer
US9901713B2 (en) 2002-09-17 2018-02-27 Medtronic, Inc. Low profile instrument immobilizer
US7636596B2 (en) 2002-12-20 2009-12-22 Medtronic, Inc. Organ access device and method
US8116850B2 (en) 2002-12-20 2012-02-14 Medtronic, Inc. Organ access device and method
WO2004058086A1 (en) * 2002-12-20 2004-07-15 Image-Guided Neurologics, Inc. Alignment device and method
US20040153083A1 (en) * 2003-01-31 2004-08-05 Howmedica Osteonics Corp. Universal alignment guide
US7241298B2 (en) 2003-01-31 2007-07-10 Howmedica Osteonics Corp. Universal alignment guide
US7658879B2 (en) 2003-02-20 2010-02-09 Medtronic, Inc. Trajectory guide with angled or patterned guide lumens or height adjustment
US7559935B2 (en) 2003-02-20 2009-07-14 Medtronic, Inc. Target depth locators for trajectory guide for introducing an instrument
US7896889B2 (en) 2003-02-20 2011-03-01 Medtronic, Inc. Trajectory guide with angled or patterned lumens or height adjustment
US7699854B2 (en) 2003-02-20 2010-04-20 Medtronic, Inc. Trajectory guide with angled or patterned guide lumens or height adjustment
US7981120B2 (en) 2003-02-20 2011-07-19 University Of South Florida Trajectory guide with angled or patterned guide lumens or height adjustment
US20050033315A1 (en) * 2003-08-01 2005-02-10 Hankins Carol A. Apparatus and method for guiding a medical device
US7695480B2 (en) * 2003-09-25 2010-04-13 Medtronic, Inc. Ball and socket trajectory guide
US20100162552A1 (en) * 2003-09-25 2010-07-01 Medtronic, Inc. Ball and Socket Trajectory Guide
US20050070920A1 (en) * 2003-09-25 2005-03-31 Image-Guided Neurologics, Inc. Ball and socket trajectory guide
US8591522B2 (en) 2003-09-25 2013-11-26 Medtronic, Inc. Ball and socket trajectory guide
US7862570B2 (en) 2003-10-03 2011-01-04 Smith & Nephew, Inc. Surgical positioners
WO2005044126A1 (en) * 2003-10-03 2005-05-19 Smith & Nephew, Inc. Surgical positioners
US8491597B2 (en) 2003-10-03 2013-07-23 Smith & Nephew, Inc. (partial interest) Surgical positioners
US7764985B2 (en) 2003-10-20 2010-07-27 Smith & Nephew, Inc. Surgical navigation system component fault interfaces and related processes
US7794467B2 (en) 2003-11-14 2010-09-14 Smith & Nephew, Inc. Adjustable surgical cutting systems
US8021368B2 (en) 2004-01-14 2011-09-20 Hudson Surgical Design, Inc. Methods and apparatus for improved cutting tools for resection
US8114083B2 (en) 2004-01-14 2012-02-14 Hudson Surgical Design, Inc. Methods and apparatus for improved drilling and milling tools for resection
US9814539B2 (en) 2004-01-14 2017-11-14 Puget Bioventures Llc Methods and apparatus for conformable prosthetic implants
US20060030944A1 (en) * 2004-01-14 2006-02-09 Haines Timothy G Methods and apparatus for enhanced retention of prosthetic implants
US8287545B2 (en) 2004-01-14 2012-10-16 Hudson Surgical Design, Inc. Methods and apparatus for enhanced retention of prosthetic implants
US8740906B2 (en) 2004-01-14 2014-06-03 Hudson Surgical Design, Inc. Method and apparatus for wireplasty bone resection
US8353914B2 (en) 2004-02-02 2013-01-15 Hudson Surgical Design, Inc. Methods and apparatus for improved profile based resection
US7477926B2 (en) 2004-03-31 2009-01-13 Smith & Nephew, Inc. Methods and apparatuses for providing a reference array input device
US8109942B2 (en) 2004-04-21 2012-02-07 Smith & Nephew, Inc. Computer-aided methods, systems, and apparatuses for shoulder arthroplasty
US7377924B2 (en) 2004-09-09 2008-05-27 Howmedica Osteonics Corp. Navigated drill guided resection block
US20060064105A1 (en) * 2004-09-09 2006-03-23 Howmedica Osteonics Corp. Navigated drill guided resection block
US7744606B2 (en) 2004-12-04 2010-06-29 Medtronic, Inc. Multi-lumen instrument guide
US7867242B2 (en) 2004-12-04 2011-01-11 Medtronic, Inc. Instrument for guiding stage apparatus and method for using same
US7497863B2 (en) 2004-12-04 2009-03-03 Medtronic, Inc. Instrument guiding stage apparatus and method for using same
US20090118743A1 (en) * 2004-12-04 2009-05-07 Medtronic, Inc. Instrument For Guiding Stage Apparatus And Method For Using Same
US7803163B2 (en) 2004-12-04 2010-09-28 Medtronic, Inc. Multiple instrument retaining assembly and methods therefor
US8177788B2 (en) 2005-02-22 2012-05-15 Smith & Nephew, Inc. In-line milling system
US20070096863A1 (en) * 2005-10-31 2007-05-03 Benito Valencia Avila System for protecting circuitry in high-temperature environments
WO2010112013A1 (en) * 2009-04-01 2010-10-07 Charité - Universitaetsmedizin Berlin Device for guiding a ventricle catheter during implantation
US20120298820A1 (en) * 2011-05-25 2012-11-29 Spiros Manolidis Surgical tool holder
US20150018835A1 (en) * 2012-01-26 2015-01-15 Smith & Nephew, Inc. Implant fixation member holder
US9289247B2 (en) * 2013-03-15 2016-03-22 Kyphon SÀRL Surgical tool holder
US20140277199A1 (en) * 2013-03-15 2014-09-18 Kyphon Sarl Surgical tool holder
WO2015032498A1 (en) * 2013-09-04 2015-03-12 Isys Medizintechnik Gmbh Device for attaching medical target devices and the like
US9707049B1 (en) * 2016-12-22 2017-07-18 The Florida International University Board Of Trustees Stereotactic device for implantation of permanent implants into a rodent brain

Similar Documents

Publication Publication Date Title
US6359959B1 (en) System for determining target positions in the body observed in CT image data
US6428547B1 (en) Detection of the shape of treatment devices
US6322567B1 (en) Bone motion tracking system
Schuller et al. A stereotaxic method for small animals using experimentally determined reference profiles
US6366796B1 (en) Method and apparatus for planning brachytherapy surgical procedures
US5107843A (en) Method and apparatus for thin needle biopsy in connection with mammography
US6752812B1 (en) Remote actuation of trajectory guide
US3357431A (en) Neurosurgical apparatus
US4256112A (en) Head positioner
US6342056B1 (en) Surgical drill guide and method for using the same
US5078140A (en) Imaging device - aided robotic stereotaxis system
US5943719A (en) Method and device for precise invasive procedures
US5281232A (en) Reference frame for stereotactic radiosurgery using skeletal fixation
US6267770B1 (en) Remote actuation of trajectory guide
US7056019B1 (en) Quality assurance phantom system
US3115140A (en) Apparatus for stereotaxic brain operations
US5354314A (en) Three-dimensional beam localization apparatus and microscope for stereotactic diagnoses or surgery mounted on robotic type arm
US20020103431A1 (en) Medical instrument guidance using stereo radiolocation
US5047036A (en) Stereotactic device
US4571180A (en) Dental instrument
US5931786A (en) Ultrasound probe support and stepping device
US20050033315A1 (en) Apparatus and method for guiding a medical device
US20050027304A1 (en) Process for the acquisition of information intended for the insertion of a locking screw into an orifice of an endomedullary device
US6185445B1 (en) MR tomograph comprising a positioning system for the exact determination of the position of a manually guided manipulator
US3073310A (en) Surgical instrument positioning device