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US3382865A - Device for taking multiple blood samples or the like - Google Patents

Device for taking multiple blood samples or the like Download PDF

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Publication number
US3382865A
US3382865A US49730965A US3382865A US 3382865 A US3382865 A US 3382865A US 49730965 A US49730965 A US 49730965A US 3382865 A US3382865 A US 3382865A
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Prior art keywords
end
tube
needle
blood
guide
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Jr Ashton L Worrall
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Ashton L. Worrall Jr.
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150015Source of blood
    • A61B5/15003Source of blood for venous or arterial blood
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150351Caps, stoppers or lids for sealing or closing a blood collection vessel or container, e.g. a test-tube or syringe barrel
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150374Details of piercing elements or protective means for preventing accidental injuries by such piercing elements
    • A61B5/150381Design of piercing elements
    • A61B5/150389Hollow piercing elements, e.g. canulas, needles, for piercing the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150374Details of piercing elements or protective means for preventing accidental injuries by such piercing elements
    • A61B5/150381Design of piercing elements
    • A61B5/150473Double-ended needles, e.g. used with pre-evacuated sampling tubes
    • A61B5/150496Details of construction of hub, i.e. element used to attach the double-ended needle to a piercing device or sampling device
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150732Needle holders, for instance for holding the needle by the hub, used for example with double-ended needle and pre-evacuated tube
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/153Devices specially adapted for taking samples of venous or arterial blood, e.g. with syringes
    • A61B5/154Devices using pre-evacuated means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/155Devices specially adapted for continuous or multiple sampling, e.g. at predetermined intervals

Description

ay 14, 1968 A. 1.. WORRALL, JR 3,382,865

DEVICE FOR TAKING MULTIPLE BLOOD SAMPLES OR THE LIKE Filed Oct 18, 1965 G I I I /6 4 r I V 22 22 24 F/e. J m

- INVENTOR ASHTON L. WORRALL .522,

By Wm A v'rys.

United States Patent 3,382,865 DEVICE FQR TAKING MULTIPLE BLOOD SAMPLES OR THE LIKE Ashton L. Worrall, In, 325 Edison-Furlong Road, Rd). 3, Doylestown, Pa. 18901 Filed Oct. 18, 1965, Ser. No. 497,309 4 Claims. (Cl. 128-4) ABSTRACT OF THE DISCLGSURE A device for taking a plurality of separate blood samples is provided and it includes a plurality of hollow cartridges having self-sealing but puncturable ends thereon received in a tube larger in diameter than the cartridges. A hollow needle sharpened at both ends engages a closed end of the tube with a portion of the needle extending outwardly of the tube and a portion extending inwardly of the tube and terminating adjacent the other end of the tube to puncture the individual cartridges as moved axially of the tube.

This invention relates to an article of manufacture which takes multiple blood samples from a patient wherein the patients vein is punctured only once, and only one sterilized hypodermic needle and syringe are used in the blood taking process.

Heretofore, there have been varioun types of clinical devices provided for taking samples of human blood, but all such devices are equipped for taking only .a single sampling of the human blood. Since in many cases more than one sample of blood may be needed for laboratory purposes, the technician taking the blood samples from the patient may need more than one sterilized hypodermic needle and other additional equipment. If more blood samples are needed, the consecutive use of prior art devices often result in undue manipulation on the part of the technician, danger and discomforture to the patient, danger of loss of sterilization, and a possible need for repeated punctures of the patient at, or around, the sampling point from which the blood is taken.

It is the general object of the present invention to overcome the stated, and other difiiculties, of the prior art by providing an inexpensive, practical apparatus by which a plurality of blood samples can be taken from a patient with the need for only one puncture at the sampling point and where only one hypodermic needle and syringe are used.

Another object of the present invention is to provide a plurality of cylindrically shaped plastic cartridges which are slidably received by the hypodermic needle and syringe which consecutively :and independently fill with the flow of blood taken from the sampling point.

Another object of the invention is to provide a hypodermic needle which not only extends longitudinally outwardly from a syringe but is also extended longitudinally inwardly in the syringe. Such a needle allows the blood sample cartridges slidably received by the syringe to be consecutively pierced by the longitudinally inwardly extending end. of the hypodermic needle.

Another object of the invention is to manufacture the blood sample cartridges with a partial vacuum therein. This enables the sample blood taken to flow easily into 3,382,865 Patented May 14, 1968 the lower pressure area of the blood sample cartridges.

Another object of the invention is to construct the hypodermic needle and syringe used in the multiple blood sample device so that the hypodermic needle may be threadably removed from the syringe after the blood samples have been taken from the patient. This permits the syringe to act as a protector for the blood sample cartridges contained therein if they need to be transported from the place the sampling was taken to a laboratory.

These and other objects of the invention which will become apparent as the description proceeds are achieved by providing a device for taking blood samples comprising a plurality of cartridges each formed of a cylindrically shaped plastic tube having a diameter of about between one-quarter inch and one inch and a length of about between one-half inch and two inches; a plurality of pairs of disposable rubber-like end caps adapted to be fitted on each end of said plastic tube to form the complete cartridge; a transparent, cylindrically shaped plastic guide tube having a closed end and an open end, said tube adapted to slidably receive at its open end, one by one, a plurality of said cartridges in a sliding, complementary relationship therewith; and a surgical needle, sharpened at both ends, threadably received at about its mid-point by the closed end of said guide tube wherein one end of said needle extends longitudinally outwardly from the closed end of said guide tube and the other end of said needle extends longitudinally inwardly from the closed end of said guide tube thereby causing the end caps of the cartridges to be pierced in turn by the longitudinally inwardly extending end of said needle when a plurality of the cartridges are slidably received by and pressed into the open end of said glass or plastic guide tube.

For a better understanding of the apparatus of the invention, reference should be had to the following drawings wherein:

FIG. 1 is a longitudinal sectional view of one preferred embodiment of the apparatus of the invention and showing the cartridges in position to be pressed into the guide tube;

FIG. 2 is a view like FIG. 1 and illustrating the blood sample cartridges as pressed in turn into the cartridge guide tube;

FIG. 3 is a side elevation of the precision hypodermic needle employed in the apparatus of the invention;

FIG. 4 is an enlarged fragmentary cross sectional view showing details of the cartridge tube and cap.

In the drawings, and looking particularly at FIG. 1, the numeral 10 generally indicates a syringe-like body or guide tube constructed of high strength transparent glass or plastic. The body 10 has an open end 12 and a closed end 14. A hollow precision hypodermic needle 16, best illustrated by FIG. 3, is adapted to be threadably received by the closed end 14 of the body. In order to facilitate this, an internally threaded metal ferrule (not shown), can be fused to the closed end of the body but the body 10 usually is made of plastic, and a metal ferrule is not always needed. A threaded sleeve is secured to the needle 16 at a point closer to one end than the other, and the threaded sleeve is releasably screwed into the ferrule.

The surgical needle 16 has been particularly adapted for use in the apparatus of the invention by sharpening both ends of the needle rather than just one end. When the needle 16 is threadably received by the closed end of the guide tube 14, (this being best indicated in 'FIGS. 1 and 2), the shorter portion of the needle -16 extends longitudinally outwardly from the closed end of the tube with the longer portion of the needle extending longitudinally inwardly from the closed end of the tube, this longer portion being contained Within the guide tube 10. Guide tube and needle lengths dependent upon number of cartridges required.

A plurality of blood sample cartridges 20 are adapted to be slidably received in the open end of the body 10. The length of the body and the needle received therein is usually dependent upon the number of blood sample cartridges required for the laboratory experiments. These blood sample cartridges 20, although they can be constructed of any suitable material, are best suited for use in the apparatus of the invention when the tube 22 is made from a high temperature resistant, cylindrically-shaped transparent plastic. Glass may also be used. Each tube 22 is capped at each end by a disposable rubber-like diaphragm end cap 24. The caps 24 are preferably made from good quality latex or like rubber. The purpose of such a disposable end cap 24 will become evident hereinafter.

In the manufacturing or assembly process of the blood sample cartridges 20, the cartridge formed by capping the tube 22 with the end caps 24 is brought to a negative internal pressure in any desired manner.

In the actual operation of the apparatus of the invention, the first step in the blood Sampling process is to puncture the skin of the patient at a point from which the blood samples are to be taken. This point is usually at some readily accessible vein with the vein being punctured by the outwardly extending end of the needle 16. By the process best indicated in FIG. 2, a blood sample cartridge 20 is slidably inserted in the open end of the body until its end cap 24 is punctured by the inwardly extending end of the needle 16. When this occurs, the partial vacuum within the blood sample cartridge and the blood pressure causes the blood taken from the patient to easily flow into the lower pressure area within the blood sample cartridge.

When the first cartridge has been filled the desired amount with the blood sample, a second cartridge is pressed inwardly against the first cartridge causing the inwardly extending end of the needle 16 to puncture the opposite end cap of the first cartridge and the leading end cap 22 of the second cartridge. In the manner hereinbefore described, the lower pressure area within the second cartridge now causes the blood to flow therein. In a like manner, when the second cartridge is full, a third cartridge 20, if needed, is pressed inwardly against the second cartridge causing the surgical needle to again puncture the opposite end cap of the second cartridge and the leading end cap of the third cartridge. It should be noted that the peripheral dimensions of each cartridge 20 are such that the cartridge assembly slides easily into the body 10.

This process can be repeated until three, four, or even more separate blood samples have been taken. When the desired number of samples have been taken, the surgical needle 16 is unscrewed and removed leaving the body 10 containing the blood sample cartridges 20. The rubberlike caps act to close and seal themselves upon withdrawal of the needle 16. The open end of the guide tube 10 is usually then capped with some suitable protective device such as a rubber stopper (not shown), permitting the entire assembly to be ready for preferably prompt transportation from the point of sampling to a laboratory where the separate samples taken can be separately analyzed. During this transportation process, the body 10 acts as a protector for the cartridges. The removal of the blood sample from each cartridge normally simply involves removing a cap 24 and pouring out the sample.

While a certain representative embodiment and details have been shown for the purpose of illustrating the invention, it will be apparent to those skilled in this art that various changes and modifications may be made therein without departing from the spirit or scope of the invention.

What is claimed is:

1. A device for taking a plurality of separate blood samples comprising a plurality of cylindrically shaped plastic tubes having a diameter of about between one-quarter inch and one inch and a length of about between one-half inch and two inches,

a pair of self-sealing end caps fitted on the ends of each of said plastic tubes and forming a cartridge-like enclosure therewith, said enclosure having a sub-atmospheric pressure therein,

a transparent, cylindrically shaped elongate glass or plastic guide tube having a closed end and an open end, said tube being of a length and size as to be adapted to slidably receive at its open end a plurality of said plastic enclosures in sliding, concentric relationship therewith, one of said plastic tubes being at least partially received in said guide tube and another plastic tube being in substantial alignment therewith, and

a hypodermic needle, sharpened at both ends, threadably engaging the closed end of said guide tube intermediate the ends of the hypodermic needle so that one end portion of said needle extends longitudinally outwardly from the closed end of said guide tube and the other end portion of said needle extends longitudinally inwardly from the closed end of said guide tube, the end portion of said needle within said guide tube extending to a point adjacent the open end of said guide tube but within said guide tube thereby causing each of said pair of end caps fitted on the ends of a plastic tube to be pierced in turn by the longitudinally inwardly extending end of said needle when one and then an additional enclosure is pushed into the open end of said glass guide tube.

2. A device for taking a plurality of separate blood samples comprising a plurality of cylindrically shaped tubes,

a pair of self-sealing end caps fitted on the ends of each of said tubes and forming a cartridge-like enclosure therewith,

a transparent, cylindrically shaped elongate guide tube having a closed end and an open end, said tube receiving at least an axially inner and an axially outer enclosure in sliding, concentric relationship therewith, and

a hypodermic needle, sharpened at both ends, threadably engaging the closed end of said guide tube intermediate the ends of the hypodermic needle so that one end portion of said needle extends longitudinally outwardly from the closed end of said guide tube and the other end portion of said needle extends longitudinally inwardly from the closed end of said guide tube, the end portion of said needle within said guide tube extending to a point adjacent the open end of said guide tube but within said guide tube, each of said pair of end caps fitted on the axially inner of said enclosures and the axially inner end cap of the axially outer enclosure being pierced in turn by the longitudinally inwardly extending end of said needle when one and then an additional enclosure is pushed into the open end of said glass guide tube to obtain separate blood samples in the said enclosures.

3. A device for taking a plurality of separate blood samples comprising a plurality of cylindrically shaped tubes,

a pair of self-sealing end caps fitted on the ends of each of said tubes and forming a cartridge-like enclosure therewith,

a transparent, cylindrically shaped elongate guide tube having a closed end and an open end, said tube receiving at least an axially inner and an axially outer enclosure in sliding, concentric relationship therewith, and

a hypodermic needle, sharpened at both ends, engaging the closed end of said guide tube intermediate the ends of the hypodermic needle so that one end portion of said needle extends longitudinally outwardly from the closed end of said guide tube and the other end portion of said needle extends longitudinally inwardly from the closed end of said guide tube, said axially inner enclosure being impaled on the longitudinally inwardly extending end of said needle, which References Cited UNITED STATES PATENTS Goodstein et a1 128-2181 Copen 12s-21s.1 Christakis 1282 Bautista 128-2 Barr et a1. 128-2 DALTON L. TRULUCK, Primary Examiner.

US3382865A 1965-10-18 1965-10-18 Device for taking multiple blood samples or the like Expired - Lifetime US3382865A (en)

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Cited By (54)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3520292A (en) * 1966-11-30 1970-07-14 Abbott Lab Unitized needle and holder
US3557778A (en) * 1968-11-18 1971-01-26 Elbert L Hughes Blood specimen collection assembly
US3580255A (en) * 1968-04-08 1971-05-25 Hugo S Cimber Aspirator
US3604410A (en) * 1968-09-11 1971-09-14 Gary L Whitacre Multitube blood sampler
US3706305A (en) * 1971-03-03 1972-12-19 Harold J Berger Combination blood sampling vacuum syringe centrifuge container and specimen cup
US3730170A (en) * 1971-04-29 1973-05-01 T Michael Apparatus for distributing a sample of blood to a plurality of cultures
US4085737A (en) * 1976-09-03 1978-04-25 Bordow Richard A Device and technique for minimizing risk of contamination by blood sample
US4228808A (en) * 1977-09-08 1980-10-21 Avl Ag Device for the withdrawal of blood
US4366822A (en) * 1979-12-03 1983-01-04 Applied Medical Devices, Inc. Method and apparatus for bone marrow cell separation and analysis
US4449539A (en) * 1980-12-30 1984-05-22 Walter Sarstedt Kunstoff-Spritzgusswerk Blood extraction device
US4784650A (en) * 1987-03-23 1988-11-15 Coburn Timothy J Needle holder
US4932944A (en) * 1988-03-09 1990-06-12 The University Of Virginia Alumni Patents Foundation Intravenous port injection and connector system
US5052927A (en) * 1988-10-24 1991-10-01 Discko John Jr Syringe and disposable capsule with cannula for use therewith
US5133362A (en) * 1990-12-28 1992-07-28 Gerald Moss Needle for use with vacuum test tube blood sampling systems
US5181523A (en) * 1990-01-16 1993-01-26 Dieter Wendelborn Blood sampling device with blood-viewing chamber
WO1994007415A1 (en) * 1992-09-30 1994-04-14 Intellectual Property Investment Corporation Multichamber container for blood or other fluid samples
US5743861A (en) * 1996-01-23 1998-04-28 Abbott Laboratories Blood collection device
US6096022A (en) * 1995-08-31 2000-08-01 Target Therapeutics Inc. Bi-directional catheter
WO2001030424A1 (en) * 1999-10-22 2001-05-03 Antares Pharma, Inc. Medicament cartridge and injection device
US6346094B2 (en) * 1998-09-28 2002-02-12 Becton, Dickinson And Company Pen needle magazine
US6533760B2 (en) 2000-05-02 2003-03-18 Becton, Dickinson And Company Flashback blood collection needle
US6712792B2 (en) 2001-05-02 2004-03-30 Becton, Dickinson And Company Flashback blood collection needle
US20050020984A1 (en) * 2002-02-15 2005-01-27 Lesch Paul R. Injector with bypass channel
US20050148939A1 (en) * 1995-06-06 2005-07-07 David Gibbs Device for targeted, catherized delivery of medications
US20050245868A1 (en) * 2004-05-03 2005-11-03 Leroy Brown Blood drawing device
US20050245885A1 (en) * 2004-05-03 2005-11-03 Leroy Brown Blood drawing device with flash detection
US20050245870A1 (en) * 2004-05-03 2005-11-03 Leroy Brown Porous multiple sample sleeve and blood drawing device for flash detection
US20050283093A1 (en) * 2004-06-02 2005-12-22 Becton, Dickinson And Company Flashback blood collection needle
US20060036219A1 (en) * 2004-08-16 2006-02-16 Bd Medical Products, Pte. Ltd. Flashback blood collection needle
US20060129064A1 (en) * 2004-11-29 2006-06-15 Becton, Dickinson And Company Blood collection set with an expanded internal volume
US20070167914A1 (en) * 2002-06-11 2007-07-19 Bd Medical Products, Pte. Ltd Flashback blood collection needle with needle shield
US20080145933A1 (en) * 2006-12-18 2008-06-19 Patton Richard G Systems and methods for parenterally procuring bodily-fluid samples with reduced contamination
US20080194986A1 (en) * 2004-06-02 2008-08-14 Becton, Dickinson And Company Blood collection set with venting mechanism
US20090088698A1 (en) * 2007-09-27 2009-04-02 Tyco Healthcare Group Lp Blood Collection Needle Assembly
US8535241B2 (en) 2011-10-13 2013-09-17 Magnolia Medical Technologies, Inc. Fluid diversion mechanism for bodily-fluid sampling
WO2014149854A1 (en) * 2013-03-19 2014-09-25 Walterspiel Juan Nepomuc Devices and methods to reduce contamination of fluid collected from a patient
US8864684B2 (en) 2011-10-13 2014-10-21 Magnolia Medical Technologies, Inc. Fluid diversion mechanism for bodily-fluid sampling
US8915889B2 (en) 2008-08-05 2014-12-23 Antares Pharma, Inc. Multiple dosage injector
US8945063B2 (en) 2009-03-20 2015-02-03 Antares Pharma, Inc. Hazardous agent injection system
US9022951B2 (en) 2012-05-30 2015-05-05 Magnolia Medical Technologies, Inc. Fluid diversion mechanism for bodily-fluid sampling
US9060724B2 (en) 2012-05-30 2015-06-23 Magnolia Medical Technologies, Inc. Fluid diversion mechanism for bodily-fluid sampling
US9149576B2 (en) 2012-10-11 2015-10-06 Magnolia Medical Technologies, Inc. Systems and methods for delivering a fluid to a patient with reduced contamination
US9155495B2 (en) 2012-11-30 2015-10-13 Magnolia Medical Technologies, Inc. Syringe-based fluid diversion mechanism for bodily fluid sampling
US9180259B2 (en) 2005-01-24 2015-11-10 Antares Pharma, Inc. Prefilled syringe jet injector
US9204864B2 (en) 2012-08-01 2015-12-08 Magnolia Medical Technologies, Inc. Fluid diversion mechanism for bodily-fluid sampling
US9220660B2 (en) 2011-07-15 2015-12-29 Antares Pharma, Inc. Liquid-transfer adapter beveled spike
US9333309B2 (en) 2002-02-11 2016-05-10 Antares Pharma, Inc. Intradermal injector
US9364610B2 (en) 2012-05-07 2016-06-14 Antares Pharma, Inc. Injection device with cammed ram assembly
US9446195B2 (en) 2011-07-15 2016-09-20 Antares Pharma, Inc. Injection device with cammed ram assembly
US9707354B2 (en) 2013-03-11 2017-07-18 Antares Pharma, Inc. Multiple dosage injector with rack and pinion dosage system
US9744302B2 (en) 2013-02-11 2017-08-29 Antares Pharma, Inc. Needle assisted jet injection device having reduced trigger force
US9788775B2 (en) 2013-03-12 2017-10-17 Magnolia Medical Technologies, Inc. Methods and apparatus for selectively occluding the lumen of a needle
US9808582B2 (en) 2006-05-03 2017-11-07 Antares Pharma, Inc. Two-stage reconstituting injector
US9931466B2 (en) 2015-08-28 2018-04-03 Magnolia Medical Tehnologies, Inc. Systems and methods for delivering a fluid to a patient with reduced contamination

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US2687728A (en) * 1951-04-25 1954-08-31 Copen Simon Irving Combination of several solutions for the hypodermic injection
US3200813A (en) * 1962-12-24 1965-08-17 George J Christakis Aspirating syringes
US3304934A (en) * 1964-09-29 1967-02-21 Dionisio O Bautista Blood drawing device
US3326206A (en) * 1966-05-31 1967-06-20 Courtland Lab Blood sampling device with releasable cannula retaining means

Cited By (90)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3520292A (en) * 1966-11-30 1970-07-14 Abbott Lab Unitized needle and holder
US3580255A (en) * 1968-04-08 1971-05-25 Hugo S Cimber Aspirator
US3604410A (en) * 1968-09-11 1971-09-14 Gary L Whitacre Multitube blood sampler
US3557778A (en) * 1968-11-18 1971-01-26 Elbert L Hughes Blood specimen collection assembly
US3706305A (en) * 1971-03-03 1972-12-19 Harold J Berger Combination blood sampling vacuum syringe centrifuge container and specimen cup
US3730170A (en) * 1971-04-29 1973-05-01 T Michael Apparatus for distributing a sample of blood to a plurality of cultures
US4085737A (en) * 1976-09-03 1978-04-25 Bordow Richard A Device and technique for minimizing risk of contamination by blood sample
US4228808A (en) * 1977-09-08 1980-10-21 Avl Ag Device for the withdrawal of blood
US4366822A (en) * 1979-12-03 1983-01-04 Applied Medical Devices, Inc. Method and apparatus for bone marrow cell separation and analysis
US4449539A (en) * 1980-12-30 1984-05-22 Walter Sarstedt Kunstoff-Spritzgusswerk Blood extraction device
US4784650A (en) * 1987-03-23 1988-11-15 Coburn Timothy J Needle holder
US4932944A (en) * 1988-03-09 1990-06-12 The University Of Virginia Alumni Patents Foundation Intravenous port injection and connector system
US5052927A (en) * 1988-10-24 1991-10-01 Discko John Jr Syringe and disposable capsule with cannula for use therewith
US5336088A (en) * 1988-10-24 1994-08-09 Centrix, Inc. Syringe and disposable capsule and method of forming capsule with cannula
US5181523A (en) * 1990-01-16 1993-01-26 Dieter Wendelborn Blood sampling device with blood-viewing chamber
US5133362A (en) * 1990-12-28 1992-07-28 Gerald Moss Needle for use with vacuum test tube blood sampling systems
WO1994007415A1 (en) * 1992-09-30 1994-04-14 Intellectual Property Investment Corporation Multichamber container for blood or other fluid samples
GB2285794A (en) * 1992-09-30 1995-07-26 Intellectual Property Invest Multichamber container for blood or other fluid samples
GB2285794B (en) * 1992-09-30 1996-01-17 Intellectual Property Invest Multichamber container for blood or other fluid samples
US5882318A (en) * 1992-09-30 1999-03-16 Tom Robin Caine Boyde Multichamber container for blood or other fluid samples
US20050148939A1 (en) * 1995-06-06 2005-07-07 David Gibbs Device for targeted, catherized delivery of medications
US6096022A (en) * 1995-08-31 2000-08-01 Target Therapeutics Inc. Bi-directional catheter
US5743861A (en) * 1996-01-23 1998-04-28 Abbott Laboratories Blood collection device
US6346094B2 (en) * 1998-09-28 2002-02-12 Becton, Dickinson And Company Pen needle magazine
WO2001030424A1 (en) * 1999-10-22 2001-05-03 Antares Pharma, Inc. Medicament cartridge and injection device
US7503907B1 (en) 1999-10-22 2009-03-17 Antares Pharma, Inc. Medicament cartridge and injection device
US6533760B2 (en) 2000-05-02 2003-03-18 Becton, Dickinson And Company Flashback blood collection needle
US6712792B2 (en) 2001-05-02 2004-03-30 Becton, Dickinson And Company Flashback blood collection needle
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