US3308821A - Disposable hypodermic syringes - Google Patents

Disposable hypodermic syringes Download PDF

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Publication number
US3308821A
US3308821A US353666A US35366664A US3308821A US 3308821 A US3308821 A US 3308821A US 353666 A US353666 A US 353666A US 35366664 A US35366664 A US 35366664A US 3308821 A US3308821 A US 3308821A
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vial
diaphragm
hypodermic needle
plunger
closing
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US353666A
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Walter A Shields
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/28—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle
    • A61M5/285—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle with sealing means to be broken or opened
    • A61M5/286—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle with sealing means to be broken or opened upon internal pressure increase, e.g. pierced or burst
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T29/00—Metal working
    • Y10T29/49—Method of mechanical manufacture
    • Y10T29/49826—Assembling or joining

Definitions

  • This invention relates to a disposable syringe embodying 'a vial containing a liquid medicament, hypodermic needle secured in one end of the vial and plunger closing the opposite end of the vial and operative to expel the liquid medicament from the vial through the hypodermic needle.
  • It is another object of the invention to provide 'a seal comprising a diaphragm which will be flexed in such a manner by the hydraulic force of the liquid medicament so that the portion of the diaphragm exposed to said force will converge on the point of the hypodermic needle and cause said needle to penetrate said exposed portion of the diaphragm and permit the liquid medicament to flow through the needle.
  • FIGURE 1 is a view of the disposable syringe partly in section and in condition for storage or shipping;
  • FIGURE 2 is a view of the syringe partly in section and showing the plunger being actuated to break the seal and expel the medicament from the vial;
  • FIGURE 3 is a longitudinal-sectional view, on an enlarged scale, of the end portion of the vial provided with the seal and the hypodermic needle with the seal in normal sealing condition;
  • FIGURE 4 is a view similar to FIGURE 3 and showing the seal being punctured by the hypodermic needle under the hydraulc force of the liquid medicament;
  • FIGURE 5 is a cross-sectional view of the seal.
  • FIGURE 6 is an end view of the seal looking at the right hand side of FIGURE 5.
  • the embodiment of the invention comprises a vial 7 of transparent material, such as glass or the like, having both ends open 'and the opening in one end being substantially of the same diameter as the diameter of the vial, as shown at 8 in FIGURES 1 and 2, and closed by a plunger 9 of resilient material, such as rubber, and having liquidsealing rings 10 to contact the inner surface of the vial and permit sliding movement of the plunger in the vial.
  • the plunger 9 is provided with a screw-threaded stud 11 projecting from the exposed end of the plunger and into the open end 8, as shown in FIGURE 1.
  • said vial is filled with a liquid medicament in through the opposite end of the vial.
  • Said opposite open end is provided with a neck portion 12 having a beaded mouth 13.
  • the neck portion 12 is sealed by a diaphragm of resilient and penetrable material, such as rubber or composition, and comprises an annular gasket portion 14 engaged on the outer end of the beaded mouth 13, and an inverted dome shaped portion consisting of a relatively thin and flexible annular side wall 15 extending from the inner side and outer end of the gasket portion 14 in an arcuate or curved direction and terminating in a wall having a stiff annular section 16 of increased 3,308,821 Patented Mar. 14, 1967 thickness adjacent to the annular wall 15 and a thin center section 17, as shown in FIGURES 5 and 6.
  • the diaphragm 14-17 is retained on the mouth 13 with the dome shaped portion 15-17 extended into said mouth by a cap member comprising a skirt portion 18 having the extremity adapted to be crimped under the inner end of the beaded mouth 13, as shown at 19.
  • a shoulder 20 is extended inwardly from the skirt portion 18 to engage and compress the diaphragm gasket portion 14 against the mouth 13.
  • a conical portion 21 is extended from the inner circumference of the shoulder 20 and terminated in a tubular portion 22.
  • the diaphragm 14-17 may be assembled on the vial mouth 13 by either of two methods.
  • One method is the positioning of the gasket portion 14 on the mouth 13 and then engaging and crimping the cap member 18-22 having the hypodermic needle 25 secured in the tubular portion 22 on the mouth with the shoulder 20 compressing the gasket portion 14.
  • the other method is inserting the diaphragm 14-17 in the cap member 18-22 against the shoulder 20 and then engaging and crimping the cap member 18-22 on the mouth 13.
  • the penetrating end 26 of the needle 25 is inserted under the skin of the patient, and the plunger 9 is pushed into the vial 7 which will create a hydraulic pressure on the diaphragm flexible wall 15 causing said wall to flex toward the conical cap portion 21, as shown at 27 in FIGURES 2 and 4, and said flexing movement of the flexible wall 15 forcibly moving the thin center section 17 past the penetrating end 24 onto the body of the hypodermic needle 25, whereby the liquid medicament is expelled through the hypodermic needle 25.
  • the gasket portion 14 will form a pivot or anchor for the flexing of the flexible wall 15 and the stiff annular section 16 will prevent the thin center section 17 from collapsing around the penetrating end 24, thereby assuring said end 24 to penetrate said thin center section 17.
  • the plunger 9 is actuated by any type of rod, such as a rod 28 having a screw-threaded recess 29 in one end for the engagement with the screw-threaded stud 11 of the plunger 9 and a manipulating knob 30 at the opposite end.
  • a rod 28 having a screw-threaded recess 29 in one end for the engagement with the screw-threaded stud 11 of the plunger 9 and a manipulating knob 30 at the opposite end.
  • a disposable syringe comprising a vial open at both ends, a plunger slidable in liquid-tight contact with the inner surface of the vial and closing one end of the vial, a diaphragm of flexible and penetratable material and closing the end of the vial opposite the end closed by the plunger, a cap member securing the diaphragm in vial closing position and forming with said diaphragm a cavity, and a hypodermic needle having opposite penetrating ends and secured in the cap member with one penetrating end positioned in said cavity, the diaphragm comprising an annular gasket portion compressed between the end of the vial and the cap member, a flexible annular portion connected at the first circumferential edge thereof to the gasket portion, a stiff annular portion connected to the second circumferential edge of the flexible annular portion, and a thin penetratable portion connected to the stiff annular portion and closing the diaphragm, whereby the hypodermic needle is sealed from the contents of the
  • a disposable syringe comprising a vial having a filler opening at one end, and a diaphragm for closing said filler opening comprising an annular gasket portion seated on said end of the vial, an annular flexible wall extended inwar-dly from the gasket portion into the vial, an annular 15 stifi portion connected to the inner circumferential edge of the flexible wall, and a thin penetrable center portion connected to the stifi portion and closing the diaphragm, whereby hydraulic pressure Within the vial will flex the flexible portion and move the stiff and thin center portions in an outward direction from the vial.

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  • Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Description

March 14, 1967 w. A. SHIELDS 3,308,821
DISPOSABLE HYPODERMIC SYRINGES 2 Sheets-Sheet 1 Filed March 23, 1964 m R Y on E l N N R E 0 V i T N T u v M B March 14, 1967 w, EL 3,308,821
DISPOSABLE HYPODERMIC SYRINGES Filed March 23, 1964 2 Sheets-Sheet 2 all/Ill INVENTOR WALTER A. SHIELDS ATTORNEY United States Patent 3,308,821 DISPOSABLE HYPODERMIC SYRINGES Walter A. Shields, Jamaica, N.Y. (38-09 24th St., Long Island City, N.Y. 11101) Filed Mar. 23, 1964, Ser. No. 353,666 3 Claims. (Cl. 128-218) This invention relates to a disposable syringe embodying 'a vial containing a liquid medicament, hypodermic needle secured in one end of the vial and plunger closing the opposite end of the vial and operative to expel the liquid medicament from the vial through the hypodermic needle.
It is an object of the invention to seal the liquid medicament in the vial from the hypodermic needle until the plunger is actuated to expel the liquid medicament when the seal is broken and the liquid medicament is expelled through the needle.
It is another object of the invention to provide 'a seal comprising a diaphragm which will be flexed in such a manner by the hydraulic force of the liquid medicament so that the portion of the diaphragm exposed to said force will converge on the point of the hypodermic needle and cause said needle to penetrate said exposed portion of the diaphragm and permit the liquid medicament to flow through the needle.
It is a further object of the invention to provide a seal which will also form a liquid-tight seal for a closure cap carrying the hypodermic needle.
Further objects and advantages of the invention will be set forth in the detailed description of the invention.
In the drawings accompanying 'and forming a part of this application:
FIGURE 1 is a view of the disposable syringe partly in section and in condition for storage or shipping;
FIGURE 2 is a view of the syringe partly in section and showing the plunger being actuated to break the seal and expel the medicament from the vial;
FIGURE 3 is a longitudinal-sectional view, on an enlarged scale, of the end portion of the vial provided with the seal and the hypodermic needle with the seal in normal sealing condition;
FIGURE 4 is a view similar to FIGURE 3 and showing the seal being punctured by the hypodermic needle under the hydraulc force of the liquid medicament;
FIGURE 5 is a cross-sectional view of the seal; and
FIGURE 6 is an end view of the seal looking at the right hand side of FIGURE 5.
The embodiment of the invention comprises a vial 7 of transparent material, such as glass or the like, having both ends open 'and the opening in one end being substantially of the same diameter as the diameter of the vial, as shown at 8 in FIGURES 1 and 2, and closed by a plunger 9 of resilient material, such as rubber, and having liquidsealing rings 10 to contact the inner surface of the vial and permit sliding movement of the plunger in the vial. The plunger 9 is provided with a screw-threaded stud 11 projecting from the exposed end of the plunger and into the open end 8, as shown in FIGURE 1.
After the plunger 9 is properly positioned in the open end 8 of the vial 7, said vial is filled with a liquid medicament in through the opposite end of the vial. Said opposite open end is provided with a neck portion 12 having a beaded mouth 13. The neck portion 12 is sealed by a diaphragm of resilient and penetrable material, such as rubber or composition, and comprises an annular gasket portion 14 engaged on the outer end of the beaded mouth 13, and an inverted dome shaped portion consisting of a relatively thin and flexible annular side wall 15 extending from the inner side and outer end of the gasket portion 14 in an arcuate or curved direction and terminating in a wall having a stiff annular section 16 of increased 3,308,821 Patented Mar. 14, 1967 thickness adjacent to the annular wall 15 and a thin center section 17, as shown in FIGURES 5 and 6.
The diaphragm 14-17 is retained on the mouth 13 with the dome shaped portion 15-17 extended into said mouth by a cap member comprising a skirt portion 18 having the extremity adapted to be crimped under the inner end of the beaded mouth 13, as shown at 19. A shoulder 20 is extended inwardly from the skirt portion 18 to engage and compress the diaphragm gasket portion 14 against the mouth 13. A conical portion 21 is extended from the inner circumference of the shoulder 20 and terminated in a tubular portion 22. When the diaphragm 14-17 and the cap member 18-22 are assembled on the vial mouth 13, there is formed a cavity 23 for the reception of a penetrating end 24 of a hypodermic needle 25 secured in the tubular portion 22 with the other penetrating end 26 positioned exteriorly of the tubular portion 22. The penetrating end 24 is positioned in contact with the diaphragm section 17, as shown in FIGURES l and 3. The diaphragm 14-17 will prevent the liquid medicament m from entering the hypodermic needle 25 until the plunger 9 is pushed into the vial 7.
The diaphragm 14-17 may be assembled on the vial mouth 13 by either of two methods. One method is the positioning of the gasket portion 14 on the mouth 13 and then engaging and crimping the cap member 18-22 having the hypodermic needle 25 secured in the tubular portion 22 on the mouth with the shoulder 20 compressing the gasket portion 14. The other method is inserting the diaphragm 14-17 in the cap member 18-22 against the shoulder 20 and then engaging and crimping the cap member 18-22 on the mouth 13.
When it is desired to inject the liquid medicament in into a patient, the penetrating end 26 of the needle 25 is inserted under the skin of the patient, and the plunger 9 is pushed into the vial 7 which will create a hydraulic pressure on the diaphragm flexible wall 15 causing said wall to flex toward the conical cap portion 21, as shown at 27 in FIGURES 2 and 4, and said flexing movement of the flexible wall 15 forcibly moving the thin center section 17 past the penetrating end 24 onto the body of the hypodermic needle 25, whereby the liquid medicament is expelled through the hypodermic needle 25. The gasket portion 14 will form a pivot or anchor for the flexing of the flexible wall 15 and the stiff annular section 16 will prevent the thin center section 17 from collapsing around the penetrating end 24, thereby assuring said end 24 to penetrate said thin center section 17.
The plunger 9 is actuated by any type of rod, such as a rod 28 having a screw-threaded recess 29 in one end for the engagement with the screw-threaded stud 11 of the plunger 9 and a manipulating knob 30 at the opposite end.
Having thus described my invention, I claim:
1. A disposable syringe comprising a vial open at both ends, a plunger slidable in liquid-tight contact with the inner surface of the vial and closing one end of the vial, a diaphragm of flexible and penetratable material and closing the end of the vial opposite the end closed by the plunger, a cap member securing the diaphragm in vial closing position and forming with said diaphragm a cavity, and a hypodermic needle having opposite penetrating ends and secured in the cap member with one penetrating end positioned in said cavity, the diaphragm comprising an annular gasket portion compressed between the end of the vial and the cap member, a flexible annular portion connected at the first circumferential edge thereof to the gasket portion, a stiff annular portion connected to the second circumferential edge of the flexible annular portion, and a thin penetratable portion connected to the stiff annular portion and closing the diaphragm, whereby the hypodermic needle is sealed from the contents of the vial and the movement of the plunger into the vial creating hydraulic pressure to forcibly flex the diaphragm flexible annular portion outwardly of the vial and forcibly move the thin penetrable portion against the penetrating end of the hypodermic needle and causing the needle to penetrate said thin penetr'able portion of the diaphragm and the flow of the contents through the hypodermic needle.
2. A disposable syringe as claimed in claim 1, wherein the flexible annular portion is of greater width than any of the other portions of the diaphragm.
3. A disposable syringe comprising a vial having a filler opening at one end, and a diaphragm for closing said filler opening comprising an annular gasket portion seated on said end of the vial, an annular flexible wall extended inwar-dly from the gasket portion into the vial, an annular 15 stifi portion connected to the inner circumferential edge of the flexible wall, and a thin penetrable center portion connected to the stifi portion and closing the diaphragm, whereby hydraulic pressure Within the vial will flex the flexible portion and move the stiff and thin center portions in an outward direction from the vial.
References Cited by the Examiner UNITED STATES PATENTS 2,646,798 7/1953 Brown 128-418 2,735,429 2/1956 Huber 128*218 2,870,766 1/1959 Dann et al 128-218 3,084,688 4/ 1963 McConnaughey 128-218 3,108,592 10/1963 Hassing et al 128-218 RICHARD A. GAUDET, Primary Examiner.
DALTON L. TRULUCK, Examiner.

Claims (1)

1. A DISPOSABLE SYRINGE COMPRISING A VIAL OPEN AT BOTH ENDS, A PLUNGER SLIDABLE IN LIQUID-TIGHT CONTACT WITH THE INNER SURFACE OF THE VIAL AND CLOSING ONE END OF THE VIAL, A DIAPHRAGM OF FLEXIBLE AND PENETRABLE MATERIAL AND CLOSING THE END OF THE VIAL OPPOSITE THE END CLOSED BY THE PLUNGER, A CAP MEMBER SECURING THE DIAPHRAGM IN VIAL CLOSING POSITION AND FORMING WITH SAID DIAPHRAGM A CAVITY, AND A HYPODERMIC NEEDLE HAVING OPPOSITE PENETRATING ENDS AND SECURED IN THE CAP MEMBER WITH ONE PENETRATING END POSITIONED IN SAID CAVITY, THE DIAPHRAGM COMPRISING AN ANNULAR GASKET PORTION COMPRESSED BETWEEN THE END OF THE VIAL AND THE CAP MEMBER, A FLEXIBLE ANNULAR PORTION CONNECTED AT THE FIRST CIRCUMFERENTIAL EDGE THEREOF TO THE GASKET PORTION, A STIFF ANNULAR PORTION CONNECTED TO THE SECOND CIRCUMFERENTIAL EDGE OF THE FLEXIBLE ANNULAR PORTION, AND A THIN PENETRABLE PORTION CONNECTED TO THE STIFF ANNULAR PORTION AND CLOSING THE DIAPHRAGM, WHEREBY THE HYPODERMIC NEEDLE IS SEALED FROM THE CONTENTS OF THE VIAL AND THE MOVEMENT OF THE PLUNGER INTO THE VIAL CREATING HYDRAULIC PRESSURE TO FORCIBLY FLEX THE DIAPHRAGM FLEXIBLE ANNULAR PORTION OUTWARDLY OF THE VIAL AND FORCIBLY MOVE THE THIN PENETRABLE PORTION AGAINST THE PENETRATING END OF THE HYPODERMIC NEEDLE AND CAUSING THE NEEDLE TO PENETRATE SAID THIN PENETRABLE PORTION OF THE DIAPHRAM AND THE FLOW OF THE CONTENTS THROUGH THE HYPODERMIC NEEDLE.
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Cited By (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3391695A (en) * 1966-06-17 1968-07-09 Stanley J. Sarnoff Cartridge with reflexed burstable diaphragm
US3410456A (en) * 1967-05-22 1968-11-12 Johnson Entpr Inc Sealing plug for a container
US3707968A (en) * 1970-10-07 1973-01-02 Sherwood Medical Ind Inc Arming cap for breech loaded syringe
US3710794A (en) * 1971-06-16 1973-01-16 W Shields Recessed diaphragm with annular grooves for hypodermic syringes
US4072149A (en) * 1976-08-09 1978-02-07 Tischlinger Edward A Nose cap and diaphragm assembly for injector
US4178928A (en) * 1977-08-10 1979-12-18 Tischlinger Edward A Self injector
EP1225939A1 (en) * 1999-10-22 2002-07-31 Antares Pharma, Inc. Medicament cartridge
US20080065015A1 (en) * 2004-11-01 2008-03-13 Richard Fiser Locking clip with trigger bushing
US7503907B1 (en) 1999-10-22 2009-03-17 Antares Pharma, Inc. Medicament cartridge and injection device
US7736332B2 (en) 2003-10-31 2010-06-15 Tyco Healthcare Group Lp Safety shield
US7963943B2 (en) 2007-09-27 2011-06-21 Tyco Healthcare Group Lp I.V. catheter assembly and needle safety device
US8348893B2 (en) 2007-12-20 2013-01-08 Covidien Lp Locking clip assembly with spring-loaded collar
US20130245559A1 (en) * 2012-03-16 2013-09-19 Becton, Dickinson And Company Drug delivery device for drug suspensions
US20140263467A1 (en) * 2013-03-15 2014-09-18 Mark David Wardle Ampoule
US20200276389A1 (en) * 2017-11-21 2020-09-03 Sanofi A Container for at least a First Injectable Medicament and Injection Device

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2646798A (en) * 1950-09-21 1953-07-28 Frank E Brown Cartridge syringe
US2735429A (en) * 1956-02-21 Hypodermic syringes
US2870766A (en) * 1956-06-06 1959-01-27 American Home Prod Cartridge for metering syringe
US3084688A (en) * 1959-07-15 1963-04-09 Robert K Mcconnaughey Disposable hypodermic syringe
US3108592A (en) * 1958-10-17 1963-10-29 Novo Terapeutisk Labor As Injection ampoule

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2735429A (en) * 1956-02-21 Hypodermic syringes
US2646798A (en) * 1950-09-21 1953-07-28 Frank E Brown Cartridge syringe
US2870766A (en) * 1956-06-06 1959-01-27 American Home Prod Cartridge for metering syringe
US3108592A (en) * 1958-10-17 1963-10-29 Novo Terapeutisk Labor As Injection ampoule
US3084688A (en) * 1959-07-15 1963-04-09 Robert K Mcconnaughey Disposable hypodermic syringe

Cited By (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3391695A (en) * 1966-06-17 1968-07-09 Stanley J. Sarnoff Cartridge with reflexed burstable diaphragm
US3410456A (en) * 1967-05-22 1968-11-12 Johnson Entpr Inc Sealing plug for a container
US3707968A (en) * 1970-10-07 1973-01-02 Sherwood Medical Ind Inc Arming cap for breech loaded syringe
US3710794A (en) * 1971-06-16 1973-01-16 W Shields Recessed diaphragm with annular grooves for hypodermic syringes
US4072149A (en) * 1976-08-09 1978-02-07 Tischlinger Edward A Nose cap and diaphragm assembly for injector
US4178928A (en) * 1977-08-10 1979-12-18 Tischlinger Edward A Self injector
US7503907B1 (en) 1999-10-22 2009-03-17 Antares Pharma, Inc. Medicament cartridge and injection device
EP1225939A1 (en) * 1999-10-22 2002-07-31 Antares Pharma, Inc. Medicament cartridge
EP1225939A4 (en) * 1999-10-22 2003-03-19 Antares Pharma Inc Medicament cartridge
US7736332B2 (en) 2003-10-31 2010-06-15 Tyco Healthcare Group Lp Safety shield
US8506528B2 (en) 2003-10-31 2013-08-13 Covidien Lp Locking clip with trigger bushing
US9089673B2 (en) 2003-10-31 2015-07-28 Covidien Lp Locking clip with trigger bushing
US7988664B2 (en) 2004-11-01 2011-08-02 Tyco Healthcare Group Lp Locking clip with trigger bushing
US20080065015A1 (en) * 2004-11-01 2008-03-13 Richard Fiser Locking clip with trigger bushing
US8313469B2 (en) 2007-09-27 2012-11-20 Tyco Healthcare Group Lp I.V. catheter assembly and needle safety device
US7963943B2 (en) 2007-09-27 2011-06-21 Tyco Healthcare Group Lp I.V. catheter assembly and needle safety device
US8348893B2 (en) 2007-12-20 2013-01-08 Covidien Lp Locking clip assembly with spring-loaded collar
US20130245559A1 (en) * 2012-03-16 2013-09-19 Becton, Dickinson And Company Drug delivery device for drug suspensions
JP2015510798A (en) * 2012-03-16 2015-04-13 ベクトン・ディキンソン・アンド・カンパニーＢｅｃｔｏｎ， Ｄｉｃｋｉｎｓｏｎ Ａｎｄ Ｃｏｍｐａｎｙ Drug delivery device for drug suspension
US10207053B2 (en) * 2012-03-16 2019-02-19 Becton, Dickinson And Company Drug delivery device for drug suspensions
US11452816B2 (en) * 2012-03-16 2022-09-27 Becton, Dickinson And Company Drug delivery device for drug suspensions
US20140263467A1 (en) * 2013-03-15 2014-09-18 Mark David Wardle Ampoule
US20200276389A1 (en) * 2017-11-21 2020-09-03 Sanofi A Container for at least a First Injectable Medicament and Injection Device

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