US3297243A - Centrifuge disc retainer - Google Patents

Centrifuge disc retainer Download PDF

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Publication number
US3297243A
US3297243A US38794264A US3297243A US 3297243 A US3297243 A US 3297243A US 38794264 A US38794264 A US 38794264A US 3297243 A US3297243 A US 3297243A
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United States
Prior art keywords
receptacle
rotor
diaphragm
arm
centrifugal force
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
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Inventor
George N Hein
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Individual
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Filing date
Publication date
Priority to US955355D priority Critical patent/UST955355I4/en
Priority claimed from US822561A external-priority patent/US3096283A/en
Priority to FR830431A priority patent/FR1260968A/en
Priority to DEB58265A priority patent/DE1150534B/en
Priority to GB2174560A priority patent/GB878606A/en
Priority claimed from US192709A external-priority patent/US3239136A/en
Priority to US26839663 priority patent/US3244363A/en
Priority to GB1393063A priority patent/GB976206A/en
Priority to GB1731964A priority patent/GB976207A/en
Priority to FR931993A priority patent/FR1360423A/en
Priority to US27775963 priority patent/US3244362A/en
Priority to DEH49054A priority patent/DE1296842B/en
Priority to FR973152A priority patent/FR1397578A/en
Priority to GB1820564A priority patent/GB993114A/en
Priority to DEH52578A priority patent/DE1295889B/en
Application filed by Individual filed Critical Individual
Priority to US38794264 priority patent/US3297243A/en
Priority to US39256764 priority patent/US3297244A/en
Priority to GB3839865A priority patent/GB1044430A/en
Priority to FR31782A priority patent/FR88696E/en
Priority to DE19651598537 priority patent/DE1598537A1/en
Priority to FR32089A priority patent/FR1448431A/en
Publication of US3297243A publication Critical patent/US3297243A/en
Application granted granted Critical
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/49—Blood
    • G01N33/491—Blood by separating the blood components
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B1/00—Centrifuges with rotary bowls provided with solid jackets for separating predominantly liquid mixtures with or without solid particles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B11/00—Feeding, charging, or discharging bowls
    • B04B11/04—Periodical feeding or discharging; Control arrangements therefor
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B11/00—Feeding, charging, or discharging bowls
    • B04B11/06—Arrangement of distributors or collectors in centrifuges
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B5/00—Other centrifuges
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B5/00—Other centrifuges
    • B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
    • B04B5/0407—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers for liquids contained in receptacles
    • B04B5/0428—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers for liquids contained in receptacles with flexible receptacles
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T292/00—Closure fasteners
    • Y10T292/08—Bolts
    • Y10T292/0801—Multiple
    • Y10T292/0848—Swinging

Definitions

  • This invention relates to a structurally and functionally improved retaining means for a receptable which contains liquid such as blood to be subjected to the action of centrifugal force and thus separate the components of the liquid solution.
  • a further object is that of designing a structure which will be of a simple and inexpensive nature and which will function in a positive manner; the operator experiencing no difllculty in applying or placing the receptacle in the assembly and removing it therefrom while the ⁇ centrifuge is at rest.
  • FIG l is a plan view of the centrifuge head assembly
  • FIG. 2 is a sectional side view of that assembly taken along the line 2 2 in the direction of the arrows in FIG. l;
  • FIG. 3 is a fragmentary sectional view of certain of the parts as shown in FIG. 2, but illustrating the positions which they assume when subjected to the action of centrifugal force.
  • the numeral 5 indicates the head assembly of a centrifuge which is preferably dish shaped to receive a similarly contoured diaphragm 6 conveniently formed of rubber.
  • a receptacle 7 which may be formed of a suitable plastic and having an outstanding peripheral flange 8 overlying a similar flange 9 of diaphragm 6.
  • a cover part of the receptacle 7 is also conveniently formed of plastic and includes a body 10 having a central upwardly extending neck portion 11.
  • An outwardly projecting flange 13 is provided at the periphery of this cover or disc and overlies flange 8.
  • An inverted dishshaped member 14 may in turn overlie disc 10 and has a central opening 15 in its base as shown in my prior application.
  • a structure to anchor and retain the receptacle 7 in position upon rotor head 5 will involve pressure creating means sensitive to the generation of centrifugal forces.
  • a form of anchoring means has been shown and includes the short arms 16 of lugs pivotally supported adjacent the periphery of the assembly. This point of support is adjacent and slightly above the position assumed by flange 13 When in contact with flange 8. Therefore, and as shown in FIG. 3, if arms 16 is swung downwardly, its lower edge will engage and press against the upper surface of the disc flange to establish and maintain the desired relationship.
  • Operating means may preferably form parts, or extensions of the lugs. To this end the latter will include arm portions 17 of greater length than arms 16 and extending beyond the point of pivotal support. The arms 17 will involve greater mass than arms 16 and swing outwardly under the action of centrifugal force to thus shift the inner short arms of the lugs in positions as illustrated in FIG. 3. Obviously, as rotation of the head assembly ceases, the lugs will assume the position shown in FIG. 2 in which it is obvious that the receptacle 7 may readily be lifted from the rotor 5. While at least two lugs should be used (at points diametrically opposite each other in the periphery of the assembly) it is preferred as shown that four lugs be provided. As the need arises, more may be employed.
  • a bezel 18 may have screw threaded connection with the head assembly. Its upper part is provided with an inwardly facing groove 19. The latter receives a wire 20 which tends to expand and thus seat within the groove. The wire passes through openings in the lugs to thus pivotally support them.
  • the bezel is interrupted by slots 21 at points where the lugs are positioned. The width of these slots is greater than that of the lugs. Accordingly, these are free to swing outwardly from the position shown in FIG. 2 to that illustrated in FIG. 3 and to return to their initial positions. It is preferred that the bezel have an inwardly extending flange 22, which will lie between the flanges 8 and 9 to furnish a fixed assembly.
  • the head assembly is stationary. Therefore, the short arms 16 of the lugs are free of all receptacle parts. Accordingly, an operator will-without difllculty-take a receptacle 7 and place the latter in position on the rotor 5 and immediately initiate operation of the centrifuge. As rotation is initiated the retaining members will swing inwardly to maintain the desired retaining relationship. After rotation has ended, then the operator will have no difllculty in removing the cover.
  • a rotatable centrifuge head assembly including an open topped rotor having a central dished-shaped recess accessible from the rotor open top, a flexible diaphragm in and conforming to saidrecess, said diaphragm providing an upper receiving surface and adapted to be flexed under fluid pressure while the rotor is rotating, a receptacle disposed upon said surface and adapted to contain liquid to be centrifuged, said receptacle having lower flexible portions adapted to be engaged by said diaphragm and adapted to be flexed along with said diaphragm to change the capacity of said receptacle, centrifugally induced retaining means carried by the rotor and automatically movable under the action of centrifugal force to grasp and retain said receptacle against said diaphragm, said retaining means comprising a plurality of spaced lugs, each pivotally supported by said assembly to provide a smaller and a ⁇ larger arm, the latter arm swing
  • a bezel providing a part of said head assembly and having an inner surface formed with an outwardly extending groove, a wire within said groove and passing through openings in said lugs to provide pivots for the latter and said bezel being formed with slots for the accommodation of said lugs.

Description

Jan. 10, 1967 Q N, HEIN 3,297,243
CENTRIFUGE DISC RETAINER Filed Aug. 6, 1964 INVENT OR.
650265 /V HE/A/ United States Patent Office 3,297,243 Patented Jan. 10, 1967 3,297,243 CENTRIFUGE DISC RETAINER George N. Hein, 331 Chesham Ave., San Carlos, Calif. 94070 Filed Aug. 6, 1964, Ser. No. 387,942 2 Claims. (Cl. 233-26) This application is a continuation-in-part of my prior application Serial No. 277,759 filed May 3, 1963, now Patent No. 3,244,362 granted April 5, 1966, and entitled, Centrifuging Apparatus and Fractionating Systern, which is, in turn, a continuation-in-part of my prior application Serial No. 822,561 filed Iune 24, 1959, now Patent No. 3,096,283 granted July 2, 1963.
This invention relates to a structurally and functionally improved retaining means for a receptable which contains liquid such as blood to be subjected to the action of centrifugal force and thus separate the components of the liquid solution.
The present teachings are particularly applicable to a centrifuge of the type shown in my prior application for United States Patent, Serial No. 277,759, filed May 3, 1963, and entitled, Centrifuging Apparatus and Fractionating System. As will hereinafter 'be apparent, the structure and principles disclosed in the present application would be equally applicable to similar apparatus.
It is a primary object of the invention to furnish a structure which will function automatically upon the centrifuge being operated and serve to anchor a liquid-containing receptacle in place in association with the centrifuge. This relationship will be maintained throughout the entire operating cycle of the apparatus.
A further object is that of designing a structure which will be of a simple and inexpensive nature and which will function in a positive manner; the operator experiencing no difllculty in applying or placing the receptacle in the assembly and removing it therefrom while the `centrifuge is at rest.
With these and other objects in mind, reference is had to the attached sheet of drawings illustrating one practical embodiment of the invention and in which:
FIG l is a plan view of the centrifuge head assembly;
FIG. 2 is a sectional side view of that assembly taken along the line 2 2 in the direction of the arrows in FIG. l; and
FIG. 3 is a fragmentary sectional view of certain of the parts as shown in FIG. 2, but illustrating the positions which they assume when subjected to the action of centrifugal force.
In these views, the numeral 5 indicates the head assembly of a centrifuge which is preferably dish shaped to receive a similarly contoured diaphragm 6 conveniently formed of rubber. In turn, disposed upon the latter is a receptacle 7 which may be formed of a suitable plastic and having an outstanding peripheral flange 8 overlying a similar flange 9 of diaphragm 6.
A cover part of the receptacle 7 is also conveniently formed of plastic and includes a body 10 having a central upwardly extending neck portion 11. An outwardly projecting flange 13 is provided at the periphery of this cover or disc and overlies flange 8. An inverted dishshaped member 14 may in turn overlie disc 10 and has a central opening 15 in its base as shown in my prior application.
A structure to anchor and retain the receptacle 7 in position upon rotor head 5 will involve pressure creating means sensitive to the generation of centrifugal forces. A form of anchoring means has been shown and includes the short arms 16 of lugs pivotally supported adjacent the periphery of the assembly. This point of support is adjacent and slightly above the position assumed by flange 13 When in contact with flange 8. Therefore, and as shown in FIG. 3, if arms 16 is swung downwardly, its lower edge will engage and press against the upper surface of the disc flange to establish and maintain the desired relationship.
Operating means may preferably form parts, or extensions of the lugs. To this end the latter will include arm portions 17 of greater length than arms 16 and extending beyond the point of pivotal support. The arms 17 will involve greater mass than arms 16 and swing outwardly under the action of centrifugal force to thus shift the inner short arms of the lugs in positions as illustrated in FIG. 3. Obviously, as rotation of the head assembly ceases, the lugs will assume the position shown in FIG. 2 in which it is obvious that the receptacle 7 may readily be lifted from the rotor 5. While at least two lugs should be used (at points diametrically opposite each other in the periphery of the assembly) it is preferred as shown that four lugs be provided. As the need arises, more may be employed.
The lugs may be supported in a manner such that they may be readily removed and will in no way interfere with the receptacle and its parts. To this end, a bezel 18 may have screw threaded connection with the head assembly. Its upper part is provided with an inwardly facing groove 19. The latter receives a wire 20 which tends to expand and thus seat within the groove. The wire passes through openings in the lugs to thus pivotally support them. As illustrated especially in FIG. 1, the bezel is interrupted by slots 21 at points where the lugs are positioned. The width of these slots is greater than that of the lugs. Accordingly, these are free to swing outwardly from the position shown in FIG. 2 to that illustrated in FIG. 3 and to return to their initial positions. It is preferred that the bezel have an inwardly extending flange 22, which will lie between the flanges 8 and 9 to furnish a fixed assembly.
Under such circumstances, the head assembly is stationary. Therefore, the short arms 16 of the lugs are free of all receptacle parts. Accordingly, an operator will-without difllculty-take a receptacle 7 and place the latter in position on the rotor 5 and immediately initiate operation of the centrifuge. As rotation is initiated the retaining members will swing inwardly to maintain the desired retaining relationship. After rotation has ended, then the operator will have no difllculty in removing the cover.
It is obvious that among others the several objects of the invention as specifically aforenoted are thus achieved. Numerous changes in construction and rearrangement of the parts may be resorted to without departing from the spirit of the invention.
I claim:
1. In combination a rotatable centrifuge head assembly including an open topped rotor having a central dished-shaped recess accessible from the rotor open top, a flexible diaphragm in and conforming to saidrecess, said diaphragm providing an upper receiving surface and adapted to be flexed under fluid pressure while the rotor is rotating, a receptacle disposed upon said surface and adapted to contain liquid to be centrifuged, said receptacle having lower flexible portions adapted to be engaged by said diaphragm and adapted to be flexed along with said diaphragm to change the capacity of said receptacle, centrifugally induced retaining means carried by the rotor and automatically movable under the action of centrifugal force to grasp and retain said receptacle against said diaphragm, said retaining means comprising a plurality of spaced lugs, each pivotally supported by said assembly to provide a smaller and a` larger arm, the latter arm swinging outwardly under the action of centrifugal force and the smaller arm moving into clamping relationship and engagement with said receptacle as said larger arm thus swings.
2. In a structure as defined in claim 1, a bezel providing a part of said head assembly and having an inner surface formed with an outwardly extending groove, a wire within said groove and passing through openings in said lugs to provide pivots for the latter and said bezel being formed with slots for the accommodation of said lugs.
References Cited by the Examiner UNITED STATES PATENTS 955,355 4/1910 Preston et al. 233-29 1,303,203 5/1910 Hughes et al. 233-21 1,709,939 4/ 1929 Hewitt 233-20 2,883,103 4/1959 Whitehead et al 233-27 3,133,882 5/1964 Mitchell et al. 233-26 FOREIGN PATENTS 1,250,997 12/ 1960 France. 1,260,968 4/ 1961 France.
M. CARY NELSON, Primary Examiner.
H. T. KLINKSIEK, Assistant Examiner.

Claims (1)

1. IN COMBINATION A ROTATABLE CENTRIFUGE HEAD ASSEMBLY INCLUDING AN OPEN TOPPED ROTOR HAVING A CENTRAL DISHED-SHAPED RECESS ACCESSIBLE FROM THE ROTOR OPEN TOP, A FLEXIBLE DIAPHRAGM IN AND CONFORMING TO SAID RECESS, SAID DIAPHRAGM PROVIDING AN UPPER RECEIVING SURFACE AND ADAPTED TO BE FLEXED UNDER FLUID PRESSURE WHILE THE ROTOR IS ROTATING, A RECEPTACLE DISPOSED UPON SAID SURFACE AND ADAPTED TO CONTAIN LIQUID TO BE CENTRIFUGED, SAID RECEPTACLE HAVING LOWER FLEXIBLE PORTIONS ADAPTED TO BE ENGAGED BY SAID DIAPGRAGM AND ADAPTED TO BE FLEXED ALONG WITH SAID DIAPHRAGM TO CHANGE THE CAPACITY OF SAID RECEPTACLE, CENTRIFUGALLY INDUCED RETAINING MEANS CARRIED BY THE ROTOR AND AUTOMATICALLY MOVABLE UNDER THE ACTION OF CENTRIFUGAL FORCE TO GRASP AND RETAIN SAID RECEPTACLE AGAINST SAID DIAPHRAGM, SAID RETAINING MEANS COMPRISING A PLURALITY OF SPACED LUGS, EACH PIVOTALLY SUPPORTED BY SAID ASSEMBLY TO PROVIDE A SMALLER AND A LARGER ARM, THE LATTER ARM SWINGING OUTWARDLY UNDER THE ACTION OF CENTRIFUGAL FORCE AND THE SMALLER ARM MOVING INTO CLAMPING RELATIONSHIP AND ENGAGEMENT WITH SAID RECEPTACLE AS SAID LARGER ARM THUS SWINGS.
US38794264 1959-06-24 1964-08-06 Centrifuge disc retainer Expired - Lifetime US3297243A (en)

Priority Applications (19)

Application Number Priority Date Filing Date Title
US955355D UST955355I4 (en) 1959-06-24
FR830431A FR1260968A (en) 1959-06-24 1960-06-18 Container for blood, and method and machine for separating precipitates from the liquid constituents of blood
DEB58265A DE1150534B (en) 1959-06-24 1960-06-18 Device for separating components of different molecular weights in a mixture
GB2174560A GB878606A (en) 1959-06-24 1960-06-21 Method and apparatus for separating mixtures of substance of different densities
US26839663 US3244363A (en) 1959-06-24 1963-03-27 Centrifuge apparatus and bag therefor
GB1393063A GB976206A (en) 1959-06-24 1963-04-08 Improvements relating to centrifuges
GB1731964A GB976207A (en) 1959-06-24 1963-04-08 Improvements relating to bags for containing material during centrifuging
FR931993A FR1360423A (en) 1959-06-24 1963-04-19 Centrifugation apparatus and method
US27775963 US3244362A (en) 1959-06-24 1963-05-03 Centrifuging apparatus and fractionating system
DEH49054A DE1296842B (en) 1959-06-24 1963-05-04 Centrifuge for separating the components of blood and similar liquid mixtures
FR973152A FR1397578A (en) 1959-06-24 1964-04-30 Centrifuge apparatus and fractionation system
GB1820564A GB993114A (en) 1959-06-24 1964-05-01 Centrifuging apparatus and fractionating system
DEH52578A DE1295889B (en) 1959-06-24 1964-05-02 Device for separating a flowable mixture of substances into fractions of different specific gravity
US38794264 US3297243A (en) 1959-06-24 1964-08-06 Centrifuge disc retainer
US39256764 US3297244A (en) 1959-06-24 1964-08-27 Centrifuge and receptacle assembly therefor
GB3839865A GB1044430A (en) 1959-06-24 1965-09-08 Improvements in centrifuges
FR31782A FR88696E (en) 1959-06-24 1965-09-17 Centrifuge apparatus and fractionation system
DE19651598537 DE1598537A1 (en) 1959-06-24 1965-09-18 Rotor for centrifugation device
FR32089A FR1448431A (en) 1959-06-24 1965-09-21 Centrifuge lid retainer

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US822561A US3096283A (en) 1959-06-24 1959-06-24 Container for blood and machine for separating precipitates from liquid blood constituents
US192709A US3239136A (en) 1962-05-07 1962-05-07 Centrifuge and centrifuge head for separating constituents of a liquid and a liner therefor
US26839663 US3244363A (en) 1959-06-24 1963-03-27 Centrifuge apparatus and bag therefor
US27775963 US3244362A (en) 1959-06-24 1963-05-03 Centrifuging apparatus and fractionating system
US38794264 US3297243A (en) 1959-06-24 1964-08-06 Centrifuge disc retainer
US39256764 US3297244A (en) 1959-06-24 1964-08-27 Centrifuge and receptacle assembly therefor
GB3839865A GB1044430A (en) 1959-06-24 1965-09-08 Improvements in centrifuges
DEH0057212 1965-09-18
FR32089A FR1448431A (en) 1959-06-24 1965-09-21 Centrifuge lid retainer

Publications (1)

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US3297243A true US3297243A (en) 1967-01-10

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Application Number Title Priority Date Filing Date
US955355D Pending UST955355I4 (en) 1959-06-24
US26839663 Expired - Lifetime US3244363A (en) 1959-06-24 1963-03-27 Centrifuge apparatus and bag therefor
US27775963 Expired - Lifetime US3244362A (en) 1959-06-24 1963-05-03 Centrifuging apparatus and fractionating system
US38794264 Expired - Lifetime US3297243A (en) 1959-06-24 1964-08-06 Centrifuge disc retainer
US39256764 Expired - Lifetime US3297244A (en) 1959-06-24 1964-08-27 Centrifuge and receptacle assembly therefor

Family Applications Before (3)

Application Number Title Priority Date Filing Date
US955355D Pending UST955355I4 (en) 1959-06-24
US26839663 Expired - Lifetime US3244363A (en) 1959-06-24 1963-03-27 Centrifuge apparatus and bag therefor
US27775963 Expired - Lifetime US3244362A (en) 1959-06-24 1963-05-03 Centrifuging apparatus and fractionating system

Family Applications After (1)

Application Number Title Priority Date Filing Date
US39256764 Expired - Lifetime US3297244A (en) 1959-06-24 1964-08-27 Centrifuge and receptacle assembly therefor

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US (5) US3244363A (en)
DE (4) DE1150534B (en)
FR (2) FR1397578A (en)
GB (5) GB878606A (en)

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US4347971A (en) * 1977-03-03 1982-09-07 Joy Manufacturing Company Centrifuge apparatus
US4392846A (en) * 1981-05-18 1983-07-12 Joy Manufacturing Company Centrifuge apparatus
US4432748A (en) * 1976-09-03 1984-02-21 Joy Manufacturing Company Centrifuge apparatus and method of operating a centrifuge
US5312319A (en) * 1992-04-29 1994-05-17 Cobe Laboratories, Inc. Centrifuge having a single swing arm for retaining a stator tube

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GB976206A (en) 1964-11-25
DE1296842B (en) 1969-06-04
US3244362A (en) 1966-04-05
FR1448431A (en) 1966-08-05
GB976207A (en) 1964-11-25
DE1598537A1 (en) 1969-10-02
DE1295889B (en) 1969-05-22
UST955355I4 (en) 1900-01-01
GB1044430A (en) 1966-09-28
US3297244A (en) 1967-01-10
US3244363A (en) 1966-04-05
GB878606A (en) 1961-10-04
GB993114A (en) 1965-05-26
DE1150534B (en) 1963-06-20
FR1397578A (en) 1965-04-30

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