US3297243A - Centrifuge disc retainer - Google Patents

Centrifuge disc retainer Download PDF

Info

Publication number
US3297243A
US3297243A US38794264A US3297243A US 3297243 A US3297243 A US 3297243A US 38794264 A US38794264 A US 38794264A US 3297243 A US3297243 A US 3297243A
Authority
US
United States
Prior art keywords
receptacle
rotor
diaphragm
arm
centrifugal force
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
Inventor
George N Hein
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to US955355D priority Critical patent/UST955355I4/en
Priority claimed from US822561A external-priority patent/US3096283A/en
Priority to DEB58265A priority patent/DE1150534B/en
Priority to FR830431A priority patent/FR1260968A/en
Priority to GB2174560A priority patent/GB878606A/en
Priority claimed from US192709A external-priority patent/US3239136A/en
Priority to US26839663 priority patent/US3244363A/en
Priority to GB1731964A priority patent/GB976207A/en
Priority to GB1393063A priority patent/GB976206A/en
Priority to FR931993A priority patent/FR1360423A/en
Priority to US27775963 priority patent/US3244362A/en
Priority to DEH49054A priority patent/DE1296842B/en
Priority to FR973152A priority patent/FR1397578A/en
Priority to GB1820564A priority patent/GB993114A/en
Priority to DEH52578A priority patent/DE1295889B/en
Application filed by Individual filed Critical Individual
Priority to US38794264 priority patent/US3297243A/en
Priority to US39256764 priority patent/US3297244A/en
Priority to GB3839865A priority patent/GB1044430A/en
Priority to FR31782A priority patent/FR88696E/en
Priority to DE19651598537 priority patent/DE1598537A1/en
Priority to FR32089A priority patent/FR1448431A/en
Publication of US3297243A publication Critical patent/US3297243A/en
Application granted granted Critical
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Images

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/49—Blood
    • G01N33/491—Blood by separating the blood components
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B1/00—Centrifuges with rotary bowls provided with solid jackets for separating predominantly liquid mixtures with or without solid particles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B11/00—Feeding, charging, or discharging bowls
    • B04B11/04—Periodical feeding or discharging; Control arrangements therefor
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B11/00—Feeding, charging, or discharging bowls
    • B04B11/06—Arrangement of distributors or collectors in centrifuges
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B5/00—Other centrifuges
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B5/00—Other centrifuges
    • B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
    • B04B5/0407—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers for liquids contained in receptacles
    • B04B5/0428—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers for liquids contained in receptacles with flexible receptacles
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T292/00—Closure fasteners
    • Y10T292/08—Bolts
    • Y10T292/0801—Multiple
    • Y10T292/0848—Swinging

Definitions

  • This invention relates to a structurally and functionally improved retaining means for a receptable which contains liquid such as blood to be subjected to the action of centrifugal force and thus separate the components of the liquid solution.
  • a further object is that of designing a structure which will be of a simple and inexpensive nature and which will function in a positive manner; the operator experiencing no difllculty in applying or placing the receptacle in the assembly and removing it therefrom while the ⁇ centrifuge is at rest.
  • FIG l is a plan view of the centrifuge head assembly
  • FIG. 2 is a sectional side view of that assembly taken along the line 2 2 in the direction of the arrows in FIG. l;
  • FIG. 3 is a fragmentary sectional view of certain of the parts as shown in FIG. 2, but illustrating the positions which they assume when subjected to the action of centrifugal force.
  • the numeral 5 indicates the head assembly of a centrifuge which is preferably dish shaped to receive a similarly contoured diaphragm 6 conveniently formed of rubber.
  • a receptacle 7 which may be formed of a suitable plastic and having an outstanding peripheral flange 8 overlying a similar flange 9 of diaphragm 6.
  • a cover part of the receptacle 7 is also conveniently formed of plastic and includes a body 10 having a central upwardly extending neck portion 11.
  • An outwardly projecting flange 13 is provided at the periphery of this cover or disc and overlies flange 8.
  • An inverted dishshaped member 14 may in turn overlie disc 10 and has a central opening 15 in its base as shown in my prior application.
  • a structure to anchor and retain the receptacle 7 in position upon rotor head 5 will involve pressure creating means sensitive to the generation of centrifugal forces.
  • a form of anchoring means has been shown and includes the short arms 16 of lugs pivotally supported adjacent the periphery of the assembly. This point of support is adjacent and slightly above the position assumed by flange 13 When in contact with flange 8. Therefore, and as shown in FIG. 3, if arms 16 is swung downwardly, its lower edge will engage and press against the upper surface of the disc flange to establish and maintain the desired relationship.
  • Operating means may preferably form parts, or extensions of the lugs. To this end the latter will include arm portions 17 of greater length than arms 16 and extending beyond the point of pivotal support. The arms 17 will involve greater mass than arms 16 and swing outwardly under the action of centrifugal force to thus shift the inner short arms of the lugs in positions as illustrated in FIG. 3. Obviously, as rotation of the head assembly ceases, the lugs will assume the position shown in FIG. 2 in which it is obvious that the receptacle 7 may readily be lifted from the rotor 5. While at least two lugs should be used (at points diametrically opposite each other in the periphery of the assembly) it is preferred as shown that four lugs be provided. As the need arises, more may be employed.
  • a bezel 18 may have screw threaded connection with the head assembly. Its upper part is provided with an inwardly facing groove 19. The latter receives a wire 20 which tends to expand and thus seat within the groove. The wire passes through openings in the lugs to thus pivotally support them.
  • the bezel is interrupted by slots 21 at points where the lugs are positioned. The width of these slots is greater than that of the lugs. Accordingly, these are free to swing outwardly from the position shown in FIG. 2 to that illustrated in FIG. 3 and to return to their initial positions. It is preferred that the bezel have an inwardly extending flange 22, which will lie between the flanges 8 and 9 to furnish a fixed assembly.
  • the head assembly is stationary. Therefore, the short arms 16 of the lugs are free of all receptacle parts. Accordingly, an operator will-without difllculty-take a receptacle 7 and place the latter in position on the rotor 5 and immediately initiate operation of the centrifuge. As rotation is initiated the retaining members will swing inwardly to maintain the desired retaining relationship. After rotation has ended, then the operator will have no difllculty in removing the cover.
  • a rotatable centrifuge head assembly including an open topped rotor having a central dished-shaped recess accessible from the rotor open top, a flexible diaphragm in and conforming to saidrecess, said diaphragm providing an upper receiving surface and adapted to be flexed under fluid pressure while the rotor is rotating, a receptacle disposed upon said surface and adapted to contain liquid to be centrifuged, said receptacle having lower flexible portions adapted to be engaged by said diaphragm and adapted to be flexed along with said diaphragm to change the capacity of said receptacle, centrifugally induced retaining means carried by the rotor and automatically movable under the action of centrifugal force to grasp and retain said receptacle against said diaphragm, said retaining means comprising a plurality of spaced lugs, each pivotally supported by said assembly to provide a smaller and a ⁇ larger arm, the latter arm swing
  • a bezel providing a part of said head assembly and having an inner surface formed with an outwardly extending groove, a wire within said groove and passing through openings in said lugs to provide pivots for the latter and said bezel being formed with slots for the accommodation of said lugs.

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Ecology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Centrifugal Separators (AREA)
  • External Artificial Organs (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Description

Jan. 10, 1967 Q N, HEIN 3,297,243
CENTRIFUGE DISC RETAINER Filed Aug. 6, 1964 INVENT OR.
650265 /V HE/A/ United States Patent Office 3,297,243 Patented Jan. 10, 1967 3,297,243 CENTRIFUGE DISC RETAINER George N. Hein, 331 Chesham Ave., San Carlos, Calif. 94070 Filed Aug. 6, 1964, Ser. No. 387,942 2 Claims. (Cl. 233-26) This application is a continuation-in-part of my prior application Serial No. 277,759 filed May 3, 1963, now Patent No. 3,244,362 granted April 5, 1966, and entitled, Centrifuging Apparatus and Fractionating Systern, which is, in turn, a continuation-in-part of my prior application Serial No. 822,561 filed Iune 24, 1959, now Patent No. 3,096,283 granted July 2, 1963.
This invention relates to a structurally and functionally improved retaining means for a receptable which contains liquid such as blood to be subjected to the action of centrifugal force and thus separate the components of the liquid solution.
The present teachings are particularly applicable to a centrifuge of the type shown in my prior application for United States Patent, Serial No. 277,759, filed May 3, 1963, and entitled, Centrifuging Apparatus and Fractionating System. As will hereinafter 'be apparent, the structure and principles disclosed in the present application would be equally applicable to similar apparatus.
It is a primary object of the invention to furnish a structure which will function automatically upon the centrifuge being operated and serve to anchor a liquid-containing receptacle in place in association with the centrifuge. This relationship will be maintained throughout the entire operating cycle of the apparatus.
A further object is that of designing a structure which will be of a simple and inexpensive nature and which will function in a positive manner; the operator experiencing no difllculty in applying or placing the receptacle in the assembly and removing it therefrom while the `centrifuge is at rest.
With these and other objects in mind, reference is had to the attached sheet of drawings illustrating one practical embodiment of the invention and in which:
FIG l is a plan view of the centrifuge head assembly;
FIG. 2 is a sectional side view of that assembly taken along the line 2 2 in the direction of the arrows in FIG. l; and
FIG. 3 is a fragmentary sectional view of certain of the parts as shown in FIG. 2, but illustrating the positions which they assume when subjected to the action of centrifugal force.
In these views, the numeral 5 indicates the head assembly of a centrifuge which is preferably dish shaped to receive a similarly contoured diaphragm 6 conveniently formed of rubber. In turn, disposed upon the latter is a receptacle 7 which may be formed of a suitable plastic and having an outstanding peripheral flange 8 overlying a similar flange 9 of diaphragm 6.
A cover part of the receptacle 7 is also conveniently formed of plastic and includes a body 10 having a central upwardly extending neck portion 11. An outwardly projecting flange 13 is provided at the periphery of this cover or disc and overlies flange 8. An inverted dishshaped member 14 may in turn overlie disc 10 and has a central opening 15 in its base as shown in my prior application.
A structure to anchor and retain the receptacle 7 in position upon rotor head 5 will involve pressure creating means sensitive to the generation of centrifugal forces. A form of anchoring means has been shown and includes the short arms 16 of lugs pivotally supported adjacent the periphery of the assembly. This point of support is adjacent and slightly above the position assumed by flange 13 When in contact with flange 8. Therefore, and as shown in FIG. 3, if arms 16 is swung downwardly, its lower edge will engage and press against the upper surface of the disc flange to establish and maintain the desired relationship.
Operating means may preferably form parts, or extensions of the lugs. To this end the latter will include arm portions 17 of greater length than arms 16 and extending beyond the point of pivotal support. The arms 17 will involve greater mass than arms 16 and swing outwardly under the action of centrifugal force to thus shift the inner short arms of the lugs in positions as illustrated in FIG. 3. Obviously, as rotation of the head assembly ceases, the lugs will assume the position shown in FIG. 2 in which it is obvious that the receptacle 7 may readily be lifted from the rotor 5. While at least two lugs should be used (at points diametrically opposite each other in the periphery of the assembly) it is preferred as shown that four lugs be provided. As the need arises, more may be employed.
The lugs may be supported in a manner such that they may be readily removed and will in no way interfere with the receptacle and its parts. To this end, a bezel 18 may have screw threaded connection with the head assembly. Its upper part is provided with an inwardly facing groove 19. The latter receives a wire 20 which tends to expand and thus seat within the groove. The wire passes through openings in the lugs to thus pivotally support them. As illustrated especially in FIG. 1, the bezel is interrupted by slots 21 at points where the lugs are positioned. The width of these slots is greater than that of the lugs. Accordingly, these are free to swing outwardly from the position shown in FIG. 2 to that illustrated in FIG. 3 and to return to their initial positions. It is preferred that the bezel have an inwardly extending flange 22, which will lie between the flanges 8 and 9 to furnish a fixed assembly.
Under such circumstances, the head assembly is stationary. Therefore, the short arms 16 of the lugs are free of all receptacle parts. Accordingly, an operator will-without difllculty-take a receptacle 7 and place the latter in position on the rotor 5 and immediately initiate operation of the centrifuge. As rotation is initiated the retaining members will swing inwardly to maintain the desired retaining relationship. After rotation has ended, then the operator will have no difllculty in removing the cover.
It is obvious that among others the several objects of the invention as specifically aforenoted are thus achieved. Numerous changes in construction and rearrangement of the parts may be resorted to without departing from the spirit of the invention.
I claim:
1. In combination a rotatable centrifuge head assembly including an open topped rotor having a central dished-shaped recess accessible from the rotor open top, a flexible diaphragm in and conforming to saidrecess, said diaphragm providing an upper receiving surface and adapted to be flexed under fluid pressure while the rotor is rotating, a receptacle disposed upon said surface and adapted to contain liquid to be centrifuged, said receptacle having lower flexible portions adapted to be engaged by said diaphragm and adapted to be flexed along with said diaphragm to change the capacity of said receptacle, centrifugally induced retaining means carried by the rotor and automatically movable under the action of centrifugal force to grasp and retain said receptacle against said diaphragm, said retaining means comprising a plurality of spaced lugs, each pivotally supported by said assembly to provide a smaller and a` larger arm, the latter arm swinging outwardly under the action of centrifugal force and the smaller arm moving into clamping relationship and engagement with said receptacle as said larger arm thus swings.
2. In a structure as defined in claim 1, a bezel providing a part of said head assembly and having an inner surface formed with an outwardly extending groove, a wire within said groove and passing through openings in said lugs to provide pivots for the latter and said bezel being formed with slots for the accommodation of said lugs.
References Cited by the Examiner UNITED STATES PATENTS 955,355 4/1910 Preston et al. 233-29 1,303,203 5/1910 Hughes et al. 233-21 1,709,939 4/ 1929 Hewitt 233-20 2,883,103 4/1959 Whitehead et al 233-27 3,133,882 5/1964 Mitchell et al. 233-26 FOREIGN PATENTS 1,250,997 12/ 1960 France. 1,260,968 4/ 1961 France.
M. CARY NELSON, Primary Examiner.
H. T. KLINKSIEK, Assistant Examiner.

Claims (1)

1. IN COMBINATION A ROTATABLE CENTRIFUGE HEAD ASSEMBLY INCLUDING AN OPEN TOPPED ROTOR HAVING A CENTRAL DISHED-SHAPED RECESS ACCESSIBLE FROM THE ROTOR OPEN TOP, A FLEXIBLE DIAPHRAGM IN AND CONFORMING TO SAID RECESS, SAID DIAPHRAGM PROVIDING AN UPPER RECEIVING SURFACE AND ADAPTED TO BE FLEXED UNDER FLUID PRESSURE WHILE THE ROTOR IS ROTATING, A RECEPTACLE DISPOSED UPON SAID SURFACE AND ADAPTED TO CONTAIN LIQUID TO BE CENTRIFUGED, SAID RECEPTACLE HAVING LOWER FLEXIBLE PORTIONS ADAPTED TO BE ENGAGED BY SAID DIAPGRAGM AND ADAPTED TO BE FLEXED ALONG WITH SAID DIAPHRAGM TO CHANGE THE CAPACITY OF SAID RECEPTACLE, CENTRIFUGALLY INDUCED RETAINING MEANS CARRIED BY THE ROTOR AND AUTOMATICALLY MOVABLE UNDER THE ACTION OF CENTRIFUGAL FORCE TO GRASP AND RETAIN SAID RECEPTACLE AGAINST SAID DIAPHRAGM, SAID RETAINING MEANS COMPRISING A PLURALITY OF SPACED LUGS, EACH PIVOTALLY SUPPORTED BY SAID ASSEMBLY TO PROVIDE A SMALLER AND A LARGER ARM, THE LATTER ARM SWINGING OUTWARDLY UNDER THE ACTION OF CENTRIFUGAL FORCE AND THE SMALLER ARM MOVING INTO CLAMPING RELATIONSHIP AND ENGAGEMENT WITH SAID RECEPTACLE AS SAID LARGER ARM THUS SWINGS.
US38794264 1959-06-24 1964-08-06 Centrifuge disc retainer Expired - Lifetime US3297243A (en)

Priority Applications (19)

Application Number Priority Date Filing Date Title
US955355D UST955355I4 (en) 1959-06-24
DEB58265A DE1150534B (en) 1959-06-24 1960-06-18 Device for separating components of different molecular weights in a mixture
FR830431A FR1260968A (en) 1959-06-24 1960-06-18 Container for blood, and method and machine for separating precipitates from the liquid constituents of blood
GB2174560A GB878606A (en) 1959-06-24 1960-06-21 Method and apparatus for separating mixtures of substance of different densities
US26839663 US3244363A (en) 1959-06-24 1963-03-27 Centrifuge apparatus and bag therefor
GB1731964A GB976207A (en) 1959-06-24 1963-04-08 Improvements relating to bags for containing material during centrifuging
GB1393063A GB976206A (en) 1959-06-24 1963-04-08 Improvements relating to centrifuges
FR931993A FR1360423A (en) 1959-06-24 1963-04-19 Centrifugation apparatus and method
US27775963 US3244362A (en) 1959-06-24 1963-05-03 Centrifuging apparatus and fractionating system
DEH49054A DE1296842B (en) 1959-06-24 1963-05-04 Centrifuge for separating the components of blood and similar liquid mixtures
FR973152A FR1397578A (en) 1959-06-24 1964-04-30 Centrifuge apparatus and fractionation system
GB1820564A GB993114A (en) 1959-06-24 1964-05-01 Centrifuging apparatus and fractionating system
DEH52578A DE1295889B (en) 1959-06-24 1964-05-02 Device for separating a flowable mixture of substances into fractions of different specific gravity
US38794264 US3297243A (en) 1959-06-24 1964-08-06 Centrifuge disc retainer
US39256764 US3297244A (en) 1959-06-24 1964-08-27 Centrifuge and receptacle assembly therefor
GB3839865A GB1044430A (en) 1959-06-24 1965-09-08 Improvements in centrifuges
FR31782A FR88696E (en) 1959-06-24 1965-09-17 Centrifuge apparatus and fractionation system
DE19651598537 DE1598537A1 (en) 1959-06-24 1965-09-18 Rotor for centrifugation device
FR32089A FR1448431A (en) 1959-06-24 1965-09-21 Centrifuge lid retainer

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US822561A US3096283A (en) 1959-06-24 1959-06-24 Container for blood and machine for separating precipitates from liquid blood constituents
US192709A US3239136A (en) 1962-05-07 1962-05-07 Centrifuge and centrifuge head for separating constituents of a liquid and a liner therefor
US26839663 US3244363A (en) 1959-06-24 1963-03-27 Centrifuge apparatus and bag therefor
US27775963 US3244362A (en) 1959-06-24 1963-05-03 Centrifuging apparatus and fractionating system
US38794264 US3297243A (en) 1959-06-24 1964-08-06 Centrifuge disc retainer
US39256764 US3297244A (en) 1959-06-24 1964-08-27 Centrifuge and receptacle assembly therefor
GB3839865A GB1044430A (en) 1959-06-24 1965-09-08 Improvements in centrifuges
DEH0057212 1965-09-18
FR32089A FR1448431A (en) 1959-06-24 1965-09-21 Centrifuge lid retainer

Publications (1)

Publication Number Publication Date
US3297243A true US3297243A (en) 1967-01-10

Family

ID=27575970

Family Applications (5)

Application Number Title Priority Date Filing Date
US955355D Pending UST955355I4 (en) 1959-06-24
US26839663 Expired - Lifetime US3244363A (en) 1959-06-24 1963-03-27 Centrifuge apparatus and bag therefor
US27775963 Expired - Lifetime US3244362A (en) 1959-06-24 1963-05-03 Centrifuging apparatus and fractionating system
US38794264 Expired - Lifetime US3297243A (en) 1959-06-24 1964-08-06 Centrifuge disc retainer
US39256764 Expired - Lifetime US3297244A (en) 1959-06-24 1964-08-27 Centrifuge and receptacle assembly therefor

Family Applications Before (3)

Application Number Title Priority Date Filing Date
US955355D Pending UST955355I4 (en) 1959-06-24
US26839663 Expired - Lifetime US3244363A (en) 1959-06-24 1963-03-27 Centrifuge apparatus and bag therefor
US27775963 Expired - Lifetime US3244362A (en) 1959-06-24 1963-05-03 Centrifuging apparatus and fractionating system

Family Applications After (1)

Application Number Title Priority Date Filing Date
US39256764 Expired - Lifetime US3297244A (en) 1959-06-24 1964-08-27 Centrifuge and receptacle assembly therefor

Country Status (4)

Country Link
US (5) US3244363A (en)
DE (4) DE1150534B (en)
FR (2) FR1397578A (en)
GB (5) GB878606A (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4347971A (en) * 1977-03-03 1982-09-07 Joy Manufacturing Company Centrifuge apparatus
US4392846A (en) * 1981-05-18 1983-07-12 Joy Manufacturing Company Centrifuge apparatus
US4432748A (en) * 1976-09-03 1984-02-21 Joy Manufacturing Company Centrifuge apparatus and method of operating a centrifuge
US5312319A (en) * 1992-04-29 1994-05-17 Cobe Laboratories, Inc. Centrifuge having a single swing arm for retaining a stator tube

Families Citing this family (127)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3350104A (en) * 1965-09-21 1967-10-31 Ventura Tool Company Seal ring retaining apparatus
US3480207A (en) * 1966-06-15 1969-11-25 Karl Strohmaier Centrifuge with efficiency measuring device
US3456875A (en) * 1966-08-18 1969-07-22 George N Hein Air driven centrifuge
GB1162301A (en) * 1967-03-10 1969-08-27 Luckham Ltd Portable Centrifuge
US3561672A (en) * 1968-03-18 1971-02-09 Baxter Laboratories Inc Washing process and centrifuge assembly
US3485445A (en) * 1968-05-22 1969-12-23 Lewis O Engel Centrifuge apparatus with flexible boot
SE372429B (en) * 1970-11-24 1974-12-23 Escher Wyss Ag
JPS542692B1 (en) * 1971-06-26 1979-02-10
US3737096A (en) * 1971-12-23 1973-06-05 Ibm Blood processing control apparatus
DE7224033U (en) * 1972-06-27 1972-10-12 Heraeus-Christ Gmbh SMALL CENTRIFUGE
US3801004A (en) * 1972-09-22 1974-04-02 Union Carbide Corp Device for collecting the contents of cuvets in a rotating spectrophotometer analyzer
US3819111A (en) * 1973-04-09 1974-06-25 Sorvall Inc Ivan Centrifuge rotor cover
JPS50107565A (en) * 1974-01-29 1975-08-25
CH584150A5 (en) * 1974-09-02 1977-01-31 Escher Wyss Ag
DE2501924C3 (en) * 1975-01-18 1981-03-26 Westfalia Separator Ag, 59302 Oelde Solid bowl centrifuge
US4007871A (en) * 1975-11-13 1977-02-15 International Business Machines Corporation Centrifuge fluid container
US4056225A (en) * 1976-04-29 1977-11-01 Norton George Hein Jr Centrifuge rotor for separating phases of a liquid
US4734089A (en) * 1976-05-14 1988-03-29 Baxter Travenol Laboratories, Inc. Centrifugal blood processing system
CA1057254A (en) * 1976-05-14 1979-06-26 Baxter Travenol Laboratories Disposable centrifugal blood processing system
US4636193A (en) * 1976-05-14 1987-01-13 Baxter Travenol Laboratories, Inc. Disposable centrifugal blood processing system
US4430072A (en) 1977-06-03 1984-02-07 International Business Machines Corporation Centrifuge assembly
US4177921A (en) * 1977-09-29 1979-12-11 Beckman Instruments, Inc. One piece chylomicron rotor liner
US4157780A (en) * 1977-11-01 1979-06-12 Union Carbide Corporation Disposable, rotatable, star-shaped enclosure for use with blood washing apparatus
US4142670A (en) * 1978-01-27 1979-03-06 Beckman Instruments, Inc. Chylomicron rotor
US4303193A (en) * 1979-01-22 1981-12-01 Haemonetics Corporation Apparatus for separating blood into components thereof
EP0015047A1 (en) * 1979-02-21 1980-09-03 FISONS plc Centrifuge assembly
US4422941A (en) * 1980-09-08 1983-12-27 University Of Pittsburgh Apparatus for liquid-solid column centrifugation chromatography and method
DE3115875C1 (en) * 1981-04-21 1982-10-28 Westfalia Separator Ag, 4740 Oelde Device for self-draining centrifugal drums for controlling an outlet valve
US4397637A (en) * 1981-07-13 1983-08-09 The Garrett Corporation Apparatus and method for centrifuging
JPS58128649U (en) * 1982-02-19 1983-08-31 株式会社久保田製作所 centrifuge
SE8206767D0 (en) * 1982-11-26 1982-11-26 Seroteknik Hb SET AND DEVICE FOR BATTERY CENTRIFUGAL SEPARATION OF BLOOD
US4530691A (en) * 1983-12-13 1985-07-23 Baxter Travenol Laboratories, Inc. Centrifuge with movable mandrel
EP0165254A1 (en) * 1983-12-13 1985-12-27 Baxter Travenol Laboratories, Inc. Flexible disposable centrifuge system
AT387341B (en) * 1984-05-02 1989-01-10 Voest Alpine Ag FULL-COAT CENTRIFUGE
US4795419A (en) * 1985-10-11 1989-01-03 Kardiothor, Inc. Centrifuge
US4692136A (en) * 1985-10-11 1987-09-08 Cardiovascular Systems Inc. Centrifuge
US4718888A (en) * 1986-03-10 1988-01-12 Cardiovascular Systems, Inc. Centrifuge bowl mount
US4798577A (en) * 1986-05-12 1989-01-17 Miles Inc. Separator device and method
JPH01502560A (en) * 1986-05-16 1989-09-07 オメガ・メディシンテクニク・アーベー Plasma transfer method and device
US5171539A (en) * 1986-06-26 1992-12-15 Coombs David H Apparatus for forming a continuous solution gradient
US5266273A (en) * 1986-06-26 1993-11-30 Coombs David H Process and apparatus for forming a solution gradient and for conducting a blotting process
US5370802A (en) * 1987-01-30 1994-12-06 Baxter International Inc. Enhanced yield platelet collection systems and methods
US5656163A (en) 1987-01-30 1997-08-12 Baxter International Inc. Chamber for use in a rotating field to separate blood components
US4834890A (en) * 1987-01-30 1989-05-30 Baxter International Inc. Centrifugation pheresis system
US5792372A (en) * 1987-01-30 1998-08-11 Baxter International, Inc. Enhanced yield collection systems and methods for obtaining concentrated platelets from platelet-rich plasma
US5067938A (en) * 1987-03-20 1991-11-26 Kabushiki Kaisha Kubota Seisakusho Centrifugal separator
SE458342B (en) * 1987-07-06 1989-03-20 Alfa Laval Ab CENTRIFUGAL SEPARATOR INCLUDING A ROTOR WITH A SEPARATION CHAMBER CONSISTING OF TWO DEPARTMENTS
US4807845A (en) * 1987-09-30 1989-02-28 Kardiothor, Inc. Tube valve
US5316667A (en) * 1989-05-26 1994-05-31 Baxter International Inc. Time based interface detection systems for blood processing apparatus
FR2665378B1 (en) * 1990-08-03 1992-10-09 Guigan Jean DEVICE FOR SEPARATING BY CENTRIFUGATION TWO PHASES FROM A SAMPLE OF A HETEROGENEOUS LIQUID, USABLE IN PARTICULAR FOR THE SEPARATION OF TOTAL BLOOD PLASMA.
US5257968A (en) * 1991-06-06 1993-11-02 Alfa Laval Separation Inc. Inflatable dam for a decanter centrifuge
US5804079A (en) * 1991-12-23 1998-09-08 Baxter International Inc. Systems and methods for reducing the number of leukocytes in cellular products like platelets harvested for therapeutic purposes
AU652888B2 (en) * 1991-12-23 1994-09-08 Baxter International Inc. Centrifugal processing system with direct access drawer
US6007725A (en) * 1991-12-23 1999-12-28 Baxter International Inc. Systems and methods for on line collection of cellular blood components that assure donor comfort
US5549834A (en) * 1991-12-23 1996-08-27 Baxter International Inc. Systems and methods for reducing the number of leukocytes in cellular products like platelets harvested for therapeutic purposes
AU663160B2 (en) * 1991-12-23 1995-09-28 Baxter International Inc. Centrifuge
US5427695A (en) * 1993-07-26 1995-06-27 Baxter International Inc. Systems and methods for on line collecting and resuspending cellular-rich blood products like platelet concentrate
DE4340678C2 (en) * 1993-11-30 2000-07-06 Hettich Andreas Gmbh & Co Kg Centrifuge for separating blood components and similar liquids
US5551942A (en) * 1993-12-22 1996-09-03 Baxter International Inc. Centrifuge with pivot-out, easy-load processing chamber
US5733253A (en) * 1994-10-13 1998-03-31 Transfusion Technologies Corporation Fluid separation system
US6632191B1 (en) 1994-10-13 2003-10-14 Haemonetics Corporation System and method for separating blood components
US5651766A (en) 1995-06-07 1997-07-29 Transfusion Technologies Corporation Blood collection and separation system
US6824506B1 (en) 2000-12-08 2004-11-30 Haemonetics Corporation Shaped diaphragm for a centrifuge system rotor
US7332125B2 (en) * 1994-10-13 2008-02-19 Haemonetics Corporation System and method for processing blood
DE19543088C1 (en) * 1995-11-18 1997-03-06 Heraeus Instr Gmbh Low cost table centrifuge for laboratories
WO1997015399A1 (en) * 1996-04-24 1997-05-01 Claude Fell Cell separation system for biological fluids like blood
SE9700495D0 (en) * 1997-02-12 1997-02-12 Omega Medicinteknik Ab Method and round bag system and centrifuge for blood treatment
SE9701423D0 (en) * 1997-04-16 1997-04-16 Omega Medicinteknik Ab Container set and device for blood separation
JP3516400B2 (en) * 1997-05-20 2004-04-05 ザイムクエスト，インク． Cell processing system
US6852074B1 (en) * 1997-05-20 2005-02-08 Zymequest, Inc. Biological processing apparatus for expressing fluid material
US6027441A (en) * 1997-07-01 2000-02-22 Baxter International Inc. Systems and methods providing a liquid-primed, single flow access chamber
US5935051A (en) * 1997-08-29 1999-08-10 Beckman Instruments, Inc. Blood separation device
US6296602B1 (en) 1999-03-17 2001-10-02 Transfusion Technologies Corporation Method for collecting platelets and other blood components from whole blood
SE516321C2 (en) 1999-05-31 2001-12-17 Gambro Inc Centrifuge for the treatment of blood and blood components
SE517032C2 (en) 1999-10-26 2002-04-02 Gambro Inc Method and apparatus for treating blood and blood components
US6835316B2 (en) * 2001-04-09 2004-12-28 Medtronic, Inc. Clam shell blood reservoir holder with index line
US20030173274A1 (en) * 2002-02-01 2003-09-18 Frank Corbin Blood component separation device, system, and method including filtration
JP4376635B2 (en) * 2002-04-16 2009-12-02 カリディアンビーシーティー、インコーポレーテッド Blood component processing system, apparatus, and method
US7090633B2 (en) * 2002-05-21 2006-08-15 Thermo Electron Laboratory Equipment Llc Centrifuge rotor lid holder device
JP4800617B2 (en) * 2002-08-23 2011-10-26 カリディアンビーシーティー、インコーポレーテッド Method and apparatus for blood component separation
US20040217069A1 (en) * 2003-04-30 2004-11-04 Immunicon Corp. Rotor assembly for the collection, separation, and sampling of rare blood cells
US7347932B2 (en) * 2003-08-25 2008-03-25 Gambro Bct, Inc. Apparatus and method for separating a volume of composite liquid into at least two components
ITMI20031715A1 (en) * 2003-09-05 2005-03-06 Dideco Spa CONTROL DEVICE IN THE DIFFERENTIATED COLLECTION OF THE
US7060018B2 (en) * 2003-09-11 2006-06-13 Cobe Cardiovascular, Inc. Centrifuge apparatus for processing blood
US7708710B2 (en) * 2003-12-23 2010-05-04 Fenwal, Inc. Method and apparatus for collecting and processing blood
US20070209708A1 (en) * 2004-06-22 2007-09-13 Gambro, Inc. Bag Assembly for the Separation of a Composite Liquid and Method for Manufacturing it
ATE452668T1 (en) 2004-12-28 2010-01-15 Caridianbct Inc APPARATUS AND METHOD FOR SEPARATING A QUANTITY OF BLOOD INTO FOUR COMPONENTS
US7473216B2 (en) * 2005-04-21 2009-01-06 Fresenius Hemocare Deutschland Gmbh Apparatus for separation of a fluid with a separation channel having a mixer component
WO2007024518A2 (en) * 2005-08-22 2007-03-01 Gambro Inc. Apparatus and method for separating a composite liquid into at least two components
US7998052B2 (en) * 2006-03-07 2011-08-16 Jacques Chammas Rotor defining a fluid separation chamber of varying volume
JP2009539495A (en) * 2006-06-07 2009-11-19 カリディアンビーシーティー、インコーポレーテッド Apparatus and method for separating a composite liquid into at least two components
JP5259595B2 (en) * 2006-09-06 2013-08-07 テルモ ビーシーティー、インコーポレーテッド Apparatus and method for separating a composite liquid into at least two components
CA2667870A1 (en) * 2006-12-20 2008-07-03 Caridianbct, Inc. Apparatus and method for separating a composite liquid into at least two components
RU2325213C1 (en) * 2007-03-07 2008-05-27 Ярославский государственный технический университет Device for separation of suspensions
EP2155286B1 (en) * 2007-05-14 2015-07-22 Terumo BCT, Inc. Apparatus and method for separating a composite liquid into at least two components
US8685258B2 (en) * 2008-02-27 2014-04-01 Fenwal, Inc. Systems and methods for conveying multiple blood components to a recipient
US8075468B2 (en) * 2008-02-27 2011-12-13 Fenwal, Inc. Systems and methods for mid-processing calculation of blood composition
US8702637B2 (en) 2008-04-14 2014-04-22 Haemonetics Corporation System and method for optimized apheresis draw and return
US8628489B2 (en) 2008-04-14 2014-01-14 Haemonetics Corporation Three-line apheresis system and method
US8454548B2 (en) * 2008-04-14 2013-06-04 Haemonetics Corporation System and method for plasma reduced platelet collection
US20090272701A1 (en) * 2008-05-02 2009-11-05 Caridianbct, Inc. Centrifuge Apparatus and Method for Selectively Reducing Forces on a Biologic Fluid
JP5554778B2 (en) * 2008-07-31 2014-07-23 テルモ ビーシーティー、インコーポレイテッド Method and apparatus for determining the yield of at least one component
US8834402B2 (en) 2009-03-12 2014-09-16 Haemonetics Corporation System and method for the re-anticoagulation of platelet rich plasma
EP2576073B1 (en) 2010-06-07 2018-06-13 Terumo BCT, Inc. Multi-unit blood processor with volume prediction
EP2595755A1 (en) 2010-07-19 2013-05-29 Terumo BCT, Inc. A centrifuge for processing blood and blood components
CN103221078B (en) 2010-11-05 2015-09-16 赫摩耐提克斯公司 For the system and method for automatization's platelet washing
US8870733B2 (en) 2010-11-19 2014-10-28 Kensey Nash Corporation Centrifuge
US8469871B2 (en) 2010-11-19 2013-06-25 Kensey Nash Corporation Centrifuge
US8394006B2 (en) 2010-11-19 2013-03-12 Kensey Nash Corporation Centrifuge
US8317672B2 (en) 2010-11-19 2012-11-27 Kensey Nash Corporation Centrifuge method and apparatus
US8556794B2 (en) 2010-11-19 2013-10-15 Kensey Nash Corporation Centrifuge
US20220031925A1 (en) 2010-11-19 2022-02-03 Dsm Ip Assets B.V. Centrifuge
US9302042B2 (en) 2010-12-30 2016-04-05 Haemonetics Corporation System and method for collecting platelets and anticipating plasma return
US11386993B2 (en) 2011-05-18 2022-07-12 Fenwal, Inc. Plasma collection with remote programming
CN102240613B (en) * 2011-06-16 2013-12-04 安徽赛而特离心机有限公司 Device for opening, locating and locking cover of disc separator
USD731237S1 (en) 2012-08-27 2015-06-09 Eppendorf Ag Thermomixer
EP3660140A1 (en) 2014-01-31 2020-06-03 DSM IP Assets B.V. Adipose tissue processing centrifuge and methods of use
WO2017041205A1 (en) * 2015-09-07 2017-03-16 Mann+Hummel Gmbh Liner with seal for rotor of centrifugal separator
KR20170136075A (en) * 2016-05-30 2017-12-11 한국전자통신연구원 Cupping device and blood analysis apparatus using the same
EP3257587B1 (en) * 2016-06-14 2018-12-26 Alfa Laval Corporate AB Centrifugal separator with dismountable bowl-hood
US10758652B2 (en) 2017-05-30 2020-09-01 Haemonetics Corporation System and method for collecting plasma
US10792416B2 (en) 2017-05-30 2020-10-06 Haemonetics Corporation System and method for collecting plasma
GB201713981D0 (en) * 2017-08-31 2017-10-18 Biosafe Sa Centrifugal separation chamber
EP4186540A1 (en) 2018-05-21 2023-05-31 Fenwal, Inc. Systems and methods for optimization of plasma collection volumes
US12033750B2 (en) 2018-05-21 2024-07-09 Fenwal, Inc. Plasma collection
US11412967B2 (en) 2018-05-21 2022-08-16 Fenwal, Inc. Systems and methods for plasma collection
CN110721825A (en) * 2019-11-13 2020-01-24 安徽科门生物科技有限公司 Cell centrifugal pumping machine for experiments

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US955355A (en) * 1906-09-08 1910-04-19 William A Preston Centrifugal separator.
US1303203A (en) * 1919-05-06 Liam owen tea
US1709939A (en) * 1923-04-07 1929-04-23 Edward R Hewitt Apparatus for centrifugal purifying of metals and the like
US2883103A (en) * 1953-03-09 1959-04-21 Technicon International Ltd Centrifuge apparatus and method
FR1250997A (en) * 1959-04-08 1961-01-13 Jenaer Glaswerk Schott & Gen Relief valve and more particularly safety valve
FR1260968A (en) * 1959-06-24 1961-05-12 Becton Dickinson Co Container for blood, and method and machine for separating precipitates from the liquid constituents of blood
US3133882A (en) * 1961-07-21 1964-05-19 Internat Equipment Company Centrifuges with retainers, retainers, and bottle stoppers for use therewith

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE252907C (en) *
US739081A (en) * 1901-11-01 1903-09-15 Hicks Gold And Silver Extraction Company Concentrating-machine.
US987613A (en) * 1910-11-14 1911-03-21 Merle G Campau Cream-tester.
US1483484A (en) * 1923-05-05 1924-02-12 Rubert Leigh Attachment for separators
US1949278A (en) * 1931-06-12 1934-02-27 American Laundry Mach Co Combined pressure and centrifugal extractor
US2141025A (en) * 1933-09-27 1938-12-20 Laval Separator Co De Centrifugal bowl
US2104162A (en) * 1935-04-08 1938-01-04 William R Macklind Centrifugal separator
US2186836A (en) * 1937-07-10 1940-01-09 John P Mcglaughlin Process and apparatus for treating materials in centrifugals
US2578484A (en) * 1942-07-04 1951-12-11 Nyrop Aage Self-discharging sludge separator
US2412099A (en) * 1943-06-24 1946-12-03 Sharples Corp Centrifugal separating apparatus
US2542456A (en) * 1947-08-26 1951-02-20 Laval Separator Co De Standardizing centrifugally separable product
US2661150A (en) * 1947-12-17 1953-12-01 Jr William G Abbott Centrifuge
US2702034A (en) * 1950-07-20 1955-02-15 Fenwal Inc Apparatus for collecting, storing, and dispensing whole blood
GB751765A (en) * 1953-03-09 1956-07-04 Technicon International Ltd Improvements in or relating to blood centrifuges
US3064647A (en) * 1957-06-13 1962-11-20 Baxter Laboratories Inc Blood component separation method and apparatus
US3009388A (en) * 1957-12-30 1961-11-21 American Optical Corp Apparatus for determining fluid fractions and sedimentataion rates
US3022937A (en) * 1958-06-09 1962-02-27 Gen Motors Corp Centrifuge for separating three components
US3096283A (en) * 1959-06-24 1963-07-02 Becton Dickinson Co Container for blood and machine for separating precipitates from liquid blood constituents
US3129175A (en) * 1959-12-31 1964-04-14 Internat Equipment Company Centrifuges
US3104225A (en) * 1960-01-29 1963-09-17 Lourdes Instr Corp Continuous flow centrifuge rotor and liner element
US3179334A (en) * 1961-09-15 1965-04-20 Pennsalt Chemicals Corp Centrifuge discharge means
US3168473A (en) * 1961-12-04 1965-02-02 Clay Adams Inc Microhematocrit reader for centrifuges
US3145173A (en) * 1962-11-26 1964-08-18 Pennsalt Chemicals Corp Centrifuge having forced solids discharge

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1303203A (en) * 1919-05-06 Liam owen tea
US955355A (en) * 1906-09-08 1910-04-19 William A Preston Centrifugal separator.
US1709939A (en) * 1923-04-07 1929-04-23 Edward R Hewitt Apparatus for centrifugal purifying of metals and the like
US2883103A (en) * 1953-03-09 1959-04-21 Technicon International Ltd Centrifuge apparatus and method
FR1250997A (en) * 1959-04-08 1961-01-13 Jenaer Glaswerk Schott & Gen Relief valve and more particularly safety valve
FR1260968A (en) * 1959-06-24 1961-05-12 Becton Dickinson Co Container for blood, and method and machine for separating precipitates from the liquid constituents of blood
US3133882A (en) * 1961-07-21 1964-05-19 Internat Equipment Company Centrifuges with retainers, retainers, and bottle stoppers for use therewith

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4432748A (en) * 1976-09-03 1984-02-21 Joy Manufacturing Company Centrifuge apparatus and method of operating a centrifuge
US4347971A (en) * 1977-03-03 1982-09-07 Joy Manufacturing Company Centrifuge apparatus
US4392846A (en) * 1981-05-18 1983-07-12 Joy Manufacturing Company Centrifuge apparatus
US5312319A (en) * 1992-04-29 1994-05-17 Cobe Laboratories, Inc. Centrifuge having a single swing arm for retaining a stator tube

Also Published As

Publication number Publication date
DE1295889B (en) 1969-05-22
GB878606A (en) 1961-10-04
GB976206A (en) 1964-11-25
FR1448431A (en) 1966-08-05
UST955355I4 (en) 1900-01-01
DE1150534B (en) 1963-06-20
FR1397578A (en) 1965-04-30
DE1598537A1 (en) 1969-10-02
US3244363A (en) 1966-04-05
US3244362A (en) 1966-04-05
US3297244A (en) 1967-01-10
GB1044430A (en) 1966-09-28
GB993114A (en) 1965-05-26
DE1296842B (en) 1969-06-04
GB976207A (en) 1964-11-25

Similar Documents

Publication Publication Date Title
US3297243A (en) Centrifuge disc retainer
US3239136A (en) Centrifuge and centrifuge head for separating constituents of a liquid and a liner therefor
US2910264A (en) Multiple suction cup
US4142670A (en) Chylomicron rotor
US3096283A (en) Container for blood and machine for separating precipitates from liquid blood constituents
US4364832A (en) Separating member in a separating tube for centrifugal separation
NO125327B (en)
US4285463A (en) Decanting centrifuge
US4400166A (en) Top loading centrifuge rotor
US3891140A (en) Centrifuge
DE69004873D1 (en) Ceramic washer for valves and valves, equipped with such washers.
EP0258652A2 (en) Centrifuge rotor having spillage containment groove
JPH11508489A (en) Selectable angle centrifuge
US3077878A (en) Massage apparatus
KR910008695A (en) Retention Clamp for Disk Storage
US2938518A (en) Container assemblies
JPS6186962A (en) Upper loading rocking basket centrifugal separator rotor
US2635617A (en) Centrifugal valve assembly
US1879441A (en) Watch cleaning machine
US3044625A (en) Load indicator for centrifugal separator
US3796109A (en) Automatic balancing device
US2086044A (en) Pressure cooker
US2681075A (en) Pivoted weight controlled vent valve for pressure cookers
SE8901804L (en) CENTRIFUG, REFERRED TO STERILE LABORATORY CENTRIFUG
JPH0578115B2 (en)