US3075639A - Hypodermic needles in blister package - Google Patents

Hypodermic needles in blister package Download PDF

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Publication number
US3075639A
US3075639A US13138A US1313860A US3075639A US 3075639 A US3075639 A US 3075639A US 13138 A US13138 A US 13138A US 1313860 A US1313860 A US 1313860A US 3075639 A US3075639 A US 3075639A
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Prior art keywords
blister
hypodermic
sheet
package
hypodermic needle
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Expired - Lifetime
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US13138A
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Lingley Robert Crawford
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Baxter International Inc
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Baxter Laboratories Inc
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Priority to US13138A priority Critical patent/US3075639A/en
Priority to GB8022/61A priority patent/GB912055A/en
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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D75/00—Packages comprising articles or materials partially or wholly enclosed in strips, sheets, blanks, tubes, or webs of flexible sheet material, e.g. in folded wrappers
    • B65D75/52—Details
    • B65D75/527—Tear-lines for separating a package into individual packages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/002—Packages specially adapted therefor, e.g. for syringes or needles, kits for diabetics
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D75/00—Packages comprising articles or materials partially or wholly enclosed in strips, sheets, blanks, tubes, or webs of flexible sheet material, e.g. in folded wrappers
    • B65D75/28—Articles or materials wholly enclosed in composite wrappers, i.e. wrappers formed by associating or interconnecting two or more sheets or blanks
    • B65D75/30—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding
    • B65D75/32—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents
    • B65D75/36—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents one sheet or blank being recessed and the other formed of relatively stiff flat sheet material, e.g. blister packages, the recess or recesses being preformed
    • B65D75/367—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents one sheet or blank being recessed and the other formed of relatively stiff flat sheet material, e.g. blister packages, the recess or recesses being preformed and forming several compartments
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D2575/00—Packages comprising articles or materials partially or wholly enclosed in strips, sheets, blanks, tubes or webs of flexible sheet material, e.g. in folded wrappers
    • B65D2575/28—Articles or materials wholly enclosed in composite wrappers, i.e. wrappers formed by association or interconnecting two or more sheets or blanks
    • B65D2575/30—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding
    • B65D2575/36—One sheet or blank being recessed and the other formed or relatively stiff flat sheet material, e.g. blister packages
    • B65D2575/361—Details
    • B65D2575/362—Details with special means for gaining access to the contents
    • B65D2575/366—Details with special means for gaining access to the contents through a preformed opening in the recessed sheet, e.g. the opening being defined by weakened lines

Definitions

  • This invention relates to a blister package for di spos able hypodermic needles in which the hypodermic'needles are storedin asterileenvironment and'which package can be readily opened for the attachment of the hypodermic needle to a hypodermic syringe while maintaining sterility of the hydopermic'needle.
  • hypodermic-needies must be sterile and maintained Sterile during storage and must be readily removed from the sterile package at time of use with a minimum of time and dexterity on the part of the operator, and without risk of compromising sterility
  • hypodermic needles were to be 'used many times, the professional user could sterilize'new hypodermic needles with the old group and treat them all alike.
  • hypodermic needles For one time'use, that is, disposable hypodermic needles, it is more convenient to have the hypodermic needles arrive at the users office in sterile -condition,"a'ttach them toa hypodermic syringe withoutbreaking sterility, use the hy podermic needle once and discard it.
  • i i i V Such single'use insures a fresh, clean, sharp' hypodermic needle for each patient and prevents any chance of transmission of bacterial or viral infection.
  • Certain viruses which can be transferred by reuse of hypodermic needles are very hardy and willlive'under sterilizing cycles which kill all bacteria andhigher'forins of life.
  • One ,of the sheets is fiat and the other has a blister drawn down into the sheet 'of a shape to contain the hypodermic needle, including its hub, and a tearing ridge extending beyond the hub of the hypodermic needle to aid in breaking open the blister.
  • both sheets of plastic be transparent, either or both can be opaque.
  • transparent the contents of the package can be easily seen and visually inspected for possible defects and also inspected by the user for size and shape to be sure that the hypodermic needle selected is satisfactory for an intended use.
  • One or more hypodermic needle packages may be formed from a pair of sheets of plastic. It is convenient to have a plurality of hypodermic needles packaged together so that for inventory purposes sheets may be counted rather than individual needles. It is preferred that such sheets have separation lines so that the individual hypodermic needles in their packages may be separated.
  • FIGURE 1 is a pictorial representaiton of a sheet of packaged hypodermic needles.
  • FIGURE 2 is a top'iview ofasingle hypodermic needle in its package.
  • FIGURE 3 is a side view in section of a single hypodermic needle in its package.
  • FIGURE-4 is a view similar to FIGURE 3, but with the package having been broken open for use.
  • FIGURE'S is "a sectional view along line 55 of FIGUREB. I p
  • a flat transparent sheet of cellulose acetate plastic 11 is 'cut to' a size and shape sufficient to give rigidity to the finished package.
  • a thickness of about 0.005 inch gives good results.
  • the thickness of the sheet is exaggerated in the figures for purposes'of clarity.
  • the upper part of the package is formed from ,a transparent plastic sheet 12 whose external dimensions are the same asthe bottom sheet .and'is formedby clamping a sheet of plastic'over a mold which is heated suihciently, to soften the plastic, and the mold isevacu'ated to draw the blister to shape.
  • the uppersheet 12 has the blister 13 of such a size that it will contain the entire hypodermic needle, including the hub,aud has a tear ridge 14 extending beyond the end of the portion which will contain the hubof approxi mately the same Width as the hub-containing portion and which extends on a diagonal towards the original sheet surface.
  • the portion of the sheet which forms the blister is thinned in the drawing.
  • the two blister sides 15 are of about the same size'as'the blister top 16 as it extends over the hub.
  • the periphery is approximately three times the initial dimension.
  • the drawing mold have rounded edges of avoid sharp corners in the blister.
  • the top of the bottom mold sheet is printed with such indicia and instructions as seem desirable, as for example, the size and length-of the hypodermic needle, the trademark of the manufacturer and instructions to a user as to how to open the package.
  • the blistered mold sheet is inverted, a hypodermic needle placed in each blister, and the bottom mold sheet placed over the assembly. The assembly is then sealed together.
  • the plastic should be one which is heat sealable. The perimeters of the two sheets are sealed together. Whereas a multiple seal die may be used in which the scaling is accomplished all at one time, it is convenient to form the longitudinal seals 17 between separate blisters and then at a later time a front seal 18 and a rear seal 19 are formed across the front and the rear of the package.
  • a wire may be placed between the heated members forming the seal so that a separation line 20 is formed in the sheets as a zone of weakness so that the separate hypodermic needles in their blisters may be broken apart without destroying the integrity of the individual sterile seals.
  • a convenient gas for this purpose is ethylene oxide which is usually used at from 10% to 20% concentration in an inert gas, such as carbon dioxide, to prevent the formation of explosive mixtures.
  • a plurality of packaged hypodermic needles is placed in a chamber, the chamber evacuated slowly to permit air trapped in the packages to escape, and then the ethylene oxide-carbon dioxide mixture is admitted under pressure which forces the ethylene oxide through the plastic sheet material, thus sterilizing the inside of the package and the hypodermic needle therein.
  • a pressure of two or three atmospheres for eighteen hours guarantees sterility. The pressure is reduced and the ethylene oxide allowed to escape by diffusion or by flushing with an inert gas and then air. The rate of change of pressure is kept such that the blisters are not broken.
  • each blister be reinforced by a protective seal 21, which seal is closely adjacent to the edges of the blister on each side.
  • This protective seal reinforces the package by uniting the upper blistered sheet and the flat sheet of plastic just adjacent to the blister, thus reducing the span and area over which the internal pressure can operate.
  • seals may be accomplished by special formed dies so that a group of seals may be formed at a single time, or standard heat sealing equipment can be used in which a heated member with a nonadhesive face, such as polytetrafiuoroethylene, is used to prevent the plastic from sticking to the heated members and each seal is separately formed.
  • a heated member with a nonadhesive face such as polytetrafiuoroethylene
  • the temperature of seal depends somewhat on the composition of the plastic sheet.
  • a cellulose acetate sheet is very satisfactory in that it may be formed and sealed at convenitntly obtainable temperatures and is permeable to ethylene oxide as a sterilizing gas.
  • Other sheet materials including cellulose butyrate or cellulose propionate or polystyrene, and sterilizing agents such as propylene oxide may be substituted if desired.
  • the sheet material can be any plastic that is heat sealable, sterilizing gas permeable, and susceptible to deep drawing.
  • the hypodermic needle consists of the hollow needle cannula 22 itself and the needle hub 23.
  • the needle hub is a standard Luer hub which may have Luer lock flange tips 24. These Luer lock flange tips extend up towards and are close to the top of the blister.
  • the individual hypodermic needle in its blister package is separated from the remainder of the group and bent on a bend line 25.
  • This line may be indicated on the sheet, but is not a zone of weakness. As the sheets are bent along this line, which is just under the hypodermic needle hub, the top of the blister 16 is drawn against the edge of the hypodermic needle hub, and
  • the top of the blister over the hub should have a thickness of not less than about 0.001 inch, nor greater than about 0.003 inch.
  • a hypodermic needle package which contains an individual hypodermic needle sterilely until time for use and which may be readily opened by fracture of the blister and which then presents the hypodermic needle hub for attachment to a hypodermic syringe without comprising sterility, which comprises: a flat sheet of heat scalable material and a blistered sheet of heat sealable material, about 0.005-inch thick, having a shaped blister conforming to the approximate shape of a hypodermic needle and thinned to about 0.0015 to 0.0025 inch at the hub-containing portion of the sheet with a tear ridge portion of the blister extending diagonally from the needleand-h-ub-containing portion of the blister, towards and intersecting at an acute angle with said flat sheet, said sheets being heat sealed together around the edges, and additionally in protective seals adjacent to the edge of the blister, and a hypodermic needle having sharp rear corners in the blister contacting the blister, whereby the blister extends over the sharp corners and may be easily ruptured by bending the sealed together sheets adjacent said hub whereby the

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Vascular Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Composite Materials (AREA)
  • Packages (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Description

Jan. 29, 1963 R. c. LINGLEY 3,075,639
HYPODERMIC NEEDLES IN BLISTER PACKAGE Filed March 7, 1960 FIG. 4
INVENTOR. ROBERT CRAWFORD LINGLEY ATTORNEY Unified S a e. Patfi 3,075,639 HYPODERMIC NEEDLES lN'BLISTER PACKAGE Robert Crawford Lingley, Dover,Mass., assignor,'by mesne assignments, to Baxter Laboratories; Inc., Morton Grove, 111., a corporation of Delaware Filed Mar. 7, 1960, Ser. No. 13,138
1 Claim. (Cl. 206-43) A This invention relates to a blister package for di spos able hypodermic needles in which the hypodermic'needles are storedin asterileenvironment and'which package can be readily opened for the attachment of the hypodermic needle to a hypodermic syringe while maintaining sterility of the hydopermic'needle. H t t t vWith the reduction in labor costs due to automation in the production of hypodermic needles it is becoming important to be able to package hypodermic needles for use, which means that the hypodermic-needies must be sterile and maintained Sterile during storage and must be readily removed from the sterile package at time of use with a minimum of time and dexterity on the part of the operator, and without risk of compromising sterility When hypodermic needles were to be 'used many times, the professional user could sterilize'new hypodermic needles with the old group and treat them all alike. For one time'use, that is, disposable hypodermic needles, it is more convenient to have the hypodermic needles arrive at the users office in sterile -condition,"a'ttach them toa hypodermic syringe withoutbreaking sterility, use the hy podermic needle once and discard it. i i i V Such single'use insures a fresh, clean, sharp' hypodermic needle for each patient and prevents any chance of transmission of bacterial or viral infection. Certain viruses which can be transferred by reuse of hypodermic needles are very hardy and willlive'under sterilizing cycles which kill all bacteria andhigher'forins of life.
between two sheets of plastic, at least one of which is preferably transparent. One ,of the sheets is fiat and the other has a blister drawn down into the sheet 'of a shape to contain the hypodermic needle, including its hub, and a tearing ridge extending beyond the hub of the hypodermic needle to aid in breaking open the blister.
Whereas it is preferred that both sheets of plastic be transparent, either or both can be opaque. When transparent, the contents of the package can be easily seen and visually inspected for possible defects and also inspected by the user for size and shape to be sure that the hypodermic needle selected is satisfactory for an intended use.
While it is preferred that the instructions and identification indicia be printed on one of the sheets, such indicia and instructions can, of course, be given separately. It is convenient to print on the upper side of the lower strip so that the printing is sealed within the package and there is no chance of smearing or smudging the inlc.
One or more hypodermic needle packages may be formed from a pair of sheets of plastic. It is convenient to have a plurality of hypodermic needles packaged together so that for inventory purposes sheets may be counted rather than individual needles. It is preferred that such sheets have separation lines so that the individual hypodermic needles in their packages may be separated.
Further details of the invention are disclosed in the following description in connection with the drawings which illustrate specific embodiments of the present invention, the full scope of which is set forth in the ap- 2 pended claim. Other advantages, objectives and novel features are apparent from the drawings inwhich:
FIGURE 1 is a pictorial representaiton of a sheet of packaged hypodermic needles.
FIGURE 2 is a top'iview ofasingle hypodermic needle in its package. I
FIGURE 3 is a side view in section of a single hypodermic needle in its package.
FIGURE-4 is a view similar to FIGURE 3, but with the package having been broken open for use.
FIGURE'S is "a sectional view along line 55 of FIGUREB. I p
A flat transparent sheet of cellulose acetate plastic 11 is 'cut to' a size and shape sufficient to give rigidity to the finished package. A thickness of about 0.005 inch gives good results. The thickness of the sheet is exaggerated in the figures for purposes'of clarity. The upper part of the package is formed from ,a transparent plastic sheet 12 whose external dimensions are the same asthe bottom sheet .and'is formedby clamping a sheet of plastic'over a mold which is heated suihciently, to soften the plastic, and the mold isevacu'ated to draw the blister to shape. The uppersheet 12 has the blister 13 of such a size that it will contain the entire hypodermic needle, including the hub,aud has a tear ridge 14 extending beyond the end of the portion which will contain the hubof approxi mately the same Width as the hub-containing portion and which extends on a diagonal towards the original sheet surface.
By so'drawing the blister from the flat sheet, the portion of the sheet which forms the blister is thinned in the drawing. As shown in FIGURE 5-, the two blister sides 15 are of about the same size'as'the blister top 16 as it extends over the hub. Thus, the periphery is approximately three times the initial dimension. Thus, if the original sheet is about 0.005 inch thick, the blister will be drawn to about one-third of this andusually runs from aminimum of about 0.0015 to. amaximum of 0.0025 inch. it is preferred that the drawing mold have rounded edges of avoid sharp corners in the blister. '1
The top of the bottom mold sheet is printed with such indicia and instructions as seem desirable, as for example, the size and length-of the hypodermic needle, the trademark of the manufacturer and instructions to a user as to how to open the package.
The blistered mold sheet is inverted, a hypodermic needle placed in each blister, and the bottom mold sheet placed over the assembly. The assembly is then sealed together. The plastic should be one which is heat sealable. The perimeters of the two sheets are sealed together. Whereas a multiple seal die may be used in which the scaling is accomplished all at one time, it is convenient to form the longitudinal seals 17 between separate blisters and then at a later time a front seal 18 and a rear seal 19 are formed across the front and the rear of the package. In forming the longitudinal seals, a wire may be placed between the heated members forming the seal so that a separation line 20 is formed in the sheets as a zone of weakness so that the separate hypodermic needles in their blisters may be broken apart without destroying the integrity of the individual sterile seals.
Whereas, other method-s may be used, such as accomplishing sterilization before the final front seal is formed, it is more convenient and more reliable to completely form the packages and then sterilize the package and its contents by a sterilizing gas which penetrates the sheets of plastic. A convenient gas for this purpose is ethylene oxide which is usually used at from 10% to 20% concentration in an inert gas, such as carbon dioxide, to prevent the formation of explosive mixtures. A plurality of packaged hypodermic needles is placed in a chamber, the chamber evacuated slowly to permit air trapped in the packages to escape, and then the ethylene oxide-carbon dioxide mixture is admitted under pressure which forces the ethylene oxide through the plastic sheet material, thus sterilizing the inside of the package and the hypodermic needle therein. A pressure of two or three atmospheres for eighteen hours guarantees sterility. The pressure is reduced and the ethylene oxide allowed to escape by diffusion or by flushing with an inert gas and then air. The rate of change of pressure is kept such that the blisters are not broken.
Inasmuch as pressure is built up in the individual packages, it is preferred that each blister be reinforced by a protective seal 21, which seal is closely adjacent to the edges of the blister on each side. This protective seal reinforces the package by uniting the upper blistered sheet and the flat sheet of plastic just adjacent to the blister, thus reducing the span and area over which the internal pressure can operate.
These seals may be accomplished by special formed dies so that a group of seals may be formed at a single time, or standard heat sealing equipment can be used in which a heated member with a nonadhesive face, such as polytetrafiuoroethylene, is used to prevent the plastic from sticking to the heated members and each seal is separately formed. Such methods of sealing are well known.
The temperature of seal depends somewhat on the composition of the plastic sheet. A cellulose acetate sheet is very satisfactory in that it may be formed and sealed at convenitntly obtainable temperatures and is permeable to ethylene oxide as a sterilizing gas. Other sheet materials, including cellulose butyrate or cellulose propionate or polystyrene, and sterilizing agents such as propylene oxide may be substituted if desired. The sheet material can be any plastic that is heat sealable, sterilizing gas permeable, and susceptible to deep drawing.
The hypodermic needle consists of the hollow needle cannula 22 itself and the needle hub 23. Conveniently, the needle hub is a standard Luer hub which may have Luer lock flange tips 24. These Luer lock flange tips extend up towards and are close to the top of the blister.
For opening, the individual hypodermic needle in its blister package is separated from the remainder of the group and bent on a bend line 25. This line may be indicated on the sheet, but is not a zone of weakness. As the sheets are bent along this line, which is just under the hypodermic needle hub, the top of the blister 16 is drawn against the edge of the hypodermic needle hub, and
being thin, fractures. This permits the tearing ridge to pull away from the hub exposing the opening in the hypodermic needle hub. Any contamination remains on the sheet so that the hypodermic needle hub is sterile. The tip of the hypodermic syringe is placed in the hypodermic needle hub, and twisted to engage the Luer lock flange tips if a Luer lock syringe is being used. The hypodermic needle can then be withdrawn from the blister and is sterile, untouched by human hands. To be readily fracturable and yet strong enough to withstand sterilizing and shipping hazards, the top of the blister over the hub should have a thickness of not less than about 0.001 inch, nor greater than about 0.003 inch.
I claim:
A hypodermic needle package which contains an individual hypodermic needle sterilely until time for use and which may be readily opened by fracture of the blister and which then presents the hypodermic needle hub for attachment to a hypodermic syringe without comprising sterility, which comprises: a flat sheet of heat scalable material and a blistered sheet of heat sealable material, about 0.005-inch thick, having a shaped blister conforming to the approximate shape of a hypodermic needle and thinned to about 0.0015 to 0.0025 inch at the hub-containing portion of the sheet with a tear ridge portion of the blister extending diagonally from the needleand-h-ub-containing portion of the blister, towards and intersecting at an acute angle with said flat sheet, said sheets being heat sealed together around the edges, and additionally in protective seals adjacent to the edge of the blister, and a hypodermic needle having sharp rear corners in the blister contacting the blister, whereby the blister extends over the sharp corners and may be easily ruptured by bending the sealed together sheets adjacent said hub whereby the thinned portion bears against the hypodermic needle hub, thus stretching said thin portion so that it ruptures, using the flat sheet as a fulcrum, to expose said hub for insertion of a hypodermic syringe without comprising sterility.
References Cited in the file of this patent UNITED STATES PATENTS
US13138A 1960-03-07 1960-03-07 Hypodermic needles in blister package Expired - Lifetime US3075639A (en)

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Cited By (37)

* Cited by examiner, † Cited by third party
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US3207302A (en) * 1962-07-10 1965-09-21 American Home Prod Tamper-proof container for hypodermic syringes
US3207299A (en) * 1964-03-04 1965-09-21 George C Sparks Package for pills and like articles
US3261459A (en) * 1965-03-23 1966-07-19 Itt Article strip carrier
US3437199A (en) * 1968-02-12 1969-04-08 Anderson Bros Mfg Co Container with self-closing cover
US3861521A (en) * 1973-04-17 1975-01-21 Mildred V Burtz Disposable suture organizer
US3889808A (en) * 1974-04-11 1975-06-17 Container Corp Sterile package
US3906656A (en) * 1974-01-24 1975-09-23 Vincent D Burke Anti-coagulant bait package for rodents including methods of making and using same
US3918579A (en) * 1972-03-30 1975-11-11 Marcus Diamant Protective wrappers for substantially solid objects
US4106621A (en) * 1976-07-26 1978-08-15 Sorenson Research Co., Inc. Combination needle cover and venipuncture device tray and method of using same
US4155454A (en) * 1977-01-12 1979-05-22 Schering Corporation Safety packaging for ampoules
US4210239A (en) * 1978-03-23 1980-07-01 Bankoku Needle Manufacturing Company Ltd. Foldable needle pack
US4266667A (en) * 1978-10-23 1981-05-12 Sakura Color Products Corporation Package of mechanical pencil refill leads
DE29719826U1 (en) * 1997-11-07 1998-12-03 Türk, Rudolf, Dr., 81735 München Injection needle set
EP0955851A1 (en) * 1995-11-23 1999-11-17 Toothpak Pty. Ltd. A toothpick dispenser for removing toothpicks individually
WO2002055403A1 (en) 2001-01-12 2002-07-18 Bongrain S.A. Easy-to-open packaging shell
US20040226848A1 (en) * 2003-05-13 2004-11-18 Michael Dunn-Rankin Rupturable bubble package
US7243794B2 (en) * 2004-07-30 2007-07-17 Ta Ching Wang Tattoo needle case with needle head protection arrangement
WO2007091153A1 (en) * 2006-02-08 2007-08-16 Ricardo Sheath Oxford Steyn Packaging container for a needle assembly
US7270239B1 (en) * 2005-01-06 2007-09-18 Ross Karen L Dental stain preventer
US20080072432A1 (en) * 2004-01-02 2008-03-27 Teys Bradley D Dispensing Utensil
WO2008092200A1 (en) * 2007-01-31 2008-08-07 Sands Innovations Pty Ltd A dispensing utensil and manufacturing method therefor
US20090123217A1 (en) * 2007-11-09 2009-05-14 Ross Karen L Dental cleanser and stain prevention apparatus
US20120223075A1 (en) * 2011-03-04 2012-09-06 Bradley Donald Teys Fracturable container
US20130178759A1 (en) * 2012-01-10 2013-07-11 Becton, Dickinson And Company Low Cost Blood Collection Set Using Blister Package
US8511500B2 (en) 2010-06-07 2013-08-20 Sands Innovations Pty. Ltd. Dispensing container
US8523016B2 (en) 2008-12-09 2013-09-03 Sands Innovations Pty Ltd. Dispensing container
US20140309596A1 (en) * 2011-11-11 2014-10-16 Sanofi-Aventis Deutschland Gmbh Needle Assembly, Drug Delivery Device and Needle Dispenser
CN104555093A (en) * 2014-12-24 2015-04-29 苏州捷碧医疗科技有限公司 Novel package for pen type syringe needle and use method thereof
CN106730144A (en) * 2016-12-29 2017-05-31 东莞产权交易中心 Transfusion needle packaging structure
WO2018187824A1 (en) * 2017-04-11 2018-10-18 Sands Innovations Ltd Fracturable container
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EP0955851A1 (en) * 1995-11-23 1999-11-17 Toothpak Pty. Ltd. A toothpick dispenser for removing toothpicks individually
EP0955851A4 (en) * 1995-11-23 2000-09-13 Toothpak Pty Ltd A toothpick dispenser for removing toothpicks individually
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US20040226848A1 (en) * 2003-05-13 2004-11-18 Michael Dunn-Rankin Rupturable bubble package
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US7270239B1 (en) * 2005-01-06 2007-09-18 Ross Karen L Dental stain preventer
WO2007091153A1 (en) * 2006-02-08 2007-08-16 Ricardo Sheath Oxford Steyn Packaging container for a needle assembly
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US20100116772A1 (en) * 2007-01-31 2010-05-13 Sands Innovations Pty Ltd. dispensing utensil and manufacturing method therefor
US8919594B2 (en) * 2007-01-31 2014-12-30 Sands Innovations Pty Ltd Dispensing container
US8021067B2 (en) 2007-11-09 2011-09-20 Ross Karen L Dental cleanser and stain prevention apparatus
US7832956B2 (en) 2007-11-09 2010-11-16 Ross Karen L Dental cleanser and stain prevention apparatus
US20090123217A1 (en) * 2007-11-09 2009-05-14 Ross Karen L Dental cleanser and stain prevention apparatus
US8523016B2 (en) 2008-12-09 2013-09-03 Sands Innovations Pty Ltd. Dispensing container
US8511500B2 (en) 2010-06-07 2013-08-20 Sands Innovations Pty. Ltd. Dispensing container
US20120223075A1 (en) * 2011-03-04 2012-09-06 Bradley Donald Teys Fracturable container
CN103429504B (en) * 2011-03-04 2015-09-02 桑德斯创新有限公司 The container that can rupture
US8485360B2 (en) * 2011-03-04 2013-07-16 Sands Innovations Pty, Ltd. Fracturable container
CN103429504A (en) * 2011-03-04 2013-12-04 桑德斯创新有限公司 Fracturable container
US20140309596A1 (en) * 2011-11-11 2014-10-16 Sanofi-Aventis Deutschland Gmbh Needle Assembly, Drug Delivery Device and Needle Dispenser
US10398361B2 (en) * 2012-01-10 2019-09-03 Becton, Dickinson And Company Low cost blood collection set using blister package
US20130178759A1 (en) * 2012-01-10 2013-07-11 Becton, Dickinson And Company Low Cost Blood Collection Set Using Blister Package
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JP2020516555A (en) * 2017-04-11 2020-06-11 サンズ イノベーションズ リミテッド Breakable container
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