US3069469A - Hydrogenation of aromatic nitriles - Google Patents

Hydrogenation of aromatic nitriles Download PDF

Info

Publication number
US3069469A
US3069469A US741233A US74123358A US3069469A US 3069469 A US3069469 A US 3069469A US 741233 A US741233 A US 741233A US 74123358 A US74123358 A US 74123358A US 3069469 A US3069469 A US 3069469A
Authority
US
United States
Prior art keywords
cobalt
nickel
hydrogenation
catalyst
aromatic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
US741233A
Inventor
John B Wilkes
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
California Research LLC
Original Assignee
California Research LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by California Research LLC filed Critical California Research LLC
Priority to US741233A priority Critical patent/US3069469A/en
Application granted granted Critical
Publication of US3069469A publication Critical patent/US3069469A/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C209/00Preparation of compounds containing amino groups bound to a carbon skeleton
    • C07C209/44Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of carboxylic acids or esters thereof in presence of ammonia or amines, or by reduction of nitriles, carboxylic acid amides, imines or imino-ethers
    • C07C209/48Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of carboxylic acids or esters thereof in presence of ammonia or amines, or by reduction of nitriles, carboxylic acid amides, imines or imino-ethers by reduction of nitriles
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J23/00Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00
    • B01J23/70Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00 of the iron group metals or copper

Definitions

  • This invention relates to a process for the hydrogenation of aromatic nitriles, and, more particularly, to a process for the hydrogenation of aromatic nitriles in the presence of a cobalt and nickel-containing catalyst.
  • aromatic nitriles can be hydrogenated to produce the corresponding amines in high yields with a minimum amount of undesirable side reactions by employing a hydrogenation catalyst containing cobalt and over percent by weight of nickel, based upon the total weight of the cobalt and nickel present. It has been discovered that the presence of nickel in the hydrogenation catalysts considerably suppresses the formation of undesirable reaction products, thus leading to high purity amine products.
  • At least one aromatic nitrite containing at least one cyano radical all directly attached to the aromatic nucleus and attached to nonadjacent carbon atoms of the aromatic nucleus is contacted with hydrogen and ammonia at a temperature of from about 100 to 400 F. and at a superatmospheric pressure in the presence of a nickel and cobalt catalyst wherein the weight ratio of the nickel to the cobalt in said catalyst is in the range of from 1:9 to :1.
  • the resulting reaction product is comprised essentially of the amine or amines corresponding to the aromatic nitrile or nitriles present in the initial feed.
  • the aromatic nitriles comprising the feed of subject process are aromatic mono and polynitriles wherein all cyano radicals are directly attached to the aromatic nucleus, and in the case of polynitriles, directly attached to nonadjacent carbon atoms of the aromatic nucleus.
  • polynitriles having cyano radicals attached to adjacent carbon atoms of the aromatic nucleus such as ortho aromatic dinitriles
  • yields of the corresponding polyamine are generally so low and side reactions so prevalent that the reaction is completely unattractive from a practical point of view.
  • Illustrative of the basic or unsubstituted compounds contemplated within the scope of the aromatic nitriles are such compounds as benzonitrile, isophthalonitrile, terephthalonitrile, 1,3,5-
  • the aromatic nitriles of the feed may have additional substituents, such as alkyl (methyl, ethyl, propyl, butyl, etc.), amide, ester groups and the like.
  • alkyl methyl, ethyl, propyl, butyl, etc.
  • amide, ester groups and the like.
  • the main requirement is that they are relatively inert during hydrogenation under the conditions of the present process.
  • examples of such compounds are the isomeric tolunitriles, cyanoethylbenzenes, dicyanotoluenes, and dimethylterephthalonitrile.
  • the groups can be attached to the carbon atoms of the aromatic nucleus either in an adjacent or non adjacent manner.
  • the additional groups can even be attached between two meta-substituted cyano groups.
  • the aromatic nitriles comprising the feed can be present either alone or in mixture or in the presence of hydrocarbons.
  • Preferred feeds are isophthalonitrile, terephthalonitrile and mixtures thereof. More preferable still is a feed stock containing isophthalonitrile and/or terephthalonitrile having associated therewith a solvent for the nitrile.
  • especially desirable solvents are aromatic hydrocarbons, particularly the isomeric Xylenes, dioxane, and aliphatic alcohols.
  • the solvent is preferably present in an amount wherein the solvent to nitrile ratio of the feed is in the range of from about 1:1 to about 10:1.
  • the hydrogenation reaction temperature can vary from about to about 400 F., with a preferred range of from about 200 to 325 F.
  • initial pressures can vary from just sufiicient to maintain the ammonia in liquid phase up to a pressure of 5000 p.s.i.g. and higher, generally preferred pressure range being from about 2500 to 3500 p.s.i.g.
  • the space rate can vary over the range of from about 0.05 to 0.3 pound of nitrile per pound of catalyst per hour.
  • the amount of hydrogen employed can vary over a range of from about 2 to 10 or more mols of hydrogen per mol of nitrile.
  • the catalyst employed in the subject process is one containing both nickel and cobalt wherein the weight ratio of nickel to cobalt lies in the range of from about 1:9 to 15:1, and preferably, from about 1:4 to 4:1. Both the cobalt and the nickel must be in the form of the metal since it has been found that catalysts containing the oxides or sulfides of these metals require operating temperatures that are too high to give even reasonable yields of the desired amine and/or polyamine. It is much preferred that the catalyst be of the unsupported type since supported cobalt-nickel catalysts give rise to considerably lower hydrogenation rates. Various promotors such as silica, thoria, and the like, can also be present if desired.
  • the catalyst can be made by pelleting a mixture of nickel and cobalt oxides, sintering at a temperature of from about 1200 to 1800 P1, and thereafter reducing with hydrogen at a temperature of from about 700 to 900 F.
  • the metal oxides can be technical grade or obtained from the thermal decomposition of carbonates, nitrates, sulfates or the like. In the case of high nickel-content catalysts, sintering temperatures can even be higher than the noted ranges.
  • the present proces is preferably conducted in continuous, fixed bed operation, i.e., the aromatic nitrile,
  • aoeaaeo 61 hydrogen, ammonia and solvent are continuously passed through a reaction vessel containing a fixed bed of catalyst. Since the reaction is exothermic, and since the ratio of ammonia to nitrile in the feed bears directly on the product yield (see below), it is preferred that the ammonia (within rather specific limitations discussed below) and/or the hydrogen be employed in excess to aid in maintaining the reaction temperature within the range of from about 100 to 400 F. However, it must be understood that the present process can be conducted by batch, fluid bed or like manner.
  • the hydrogenation reaction of the present invention is conducted at a temperature of from about to 400 F., and preferably from about 200 to 325 F. At temperatures below about F., the reaction rate is too slow to be commercially attractive. At temperatures above about 350 F., undesirable hydrogenolysis of the amine product begins to occur and reaches appreciable amounts above 400 F. Although this reaction is particularly prevalent with cobalt catalysts even under moderate conditions (as shown in Table I), it also occurs to a lesser degree with nickel-cobalt catalysts at temperatures above about 350 F. This effect is shown by the hydrogenation runs summarized in Table III. All catalysts were made and the conditions the same as the hydrogenation operations described in Table II except where specific conditions are here described or shown in Table III. The catalysts used in the runs indicated in Table III all had nickel to cobalt weight ratios of 1:1 and ammonia to isophthalonitrile weight ratios of 1:1 and the reactions were conducted under a pressure of 3000 p.s.i.g.
  • the hydrogenation process of the present invention is primarily directed to the hydrogenation of aromatic nitriles inasmuch as it has been found that nickel-cobalt catalysts are not as effective in hydrogenating aliphatic nitriles as cobalt catalysts.
  • nickel-cobalt catalysts are not as effective in hydrogenating aliphatic nitriles as cobalt catalysts.
  • catalysts of high nickel content gave low yields of hexamethylenediamine even when using high ammonia to nitrile feed ratios. This was in distinct contrast to the above-described high yields of, for example, metaxylylenediamine obtained from isophthalonitrile with the same catalyst and similar reaction conditions.
  • a process for reducing a mononuclear aromatic nitrile to an amine, wherein said aromatic nitrile has at least one cyano group directly attached to the aromatic nucleus in other than ortho relationship to other cyano groups so attached and is otherwise unsubstituted which comprises reacting said nitrile with hydrogen and ammonia at a temperature of from about 100 to 400 F.

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Description

' atent dice 3,050,469 Patented Dec. 18, 1962 3,069,469 HYDROGENATEON F AROMATIC NITRILES John B. Wilkes, Albany, Califi, assignor to California Research Corporation, San Francisco, Calif., a corporation of Delaware No Drawing. Filed June 11, 1958, Scr. No. 741,233 5 Claims. (Cl. 260-5703) This invention relates to a process for the hydrogenation of aromatic nitriles, and, more particularly, to a process for the hydrogenation of aromatic nitriles in the presence of a cobalt and nickel-containing catalyst.
At the present time the hydrogenation of adiponitrile to hexamethylenediamine is being practiced on a commercial scale. The reaction is carried out at relatively low temperatures and high pressures over a metallic cobalt hydrogenation catalyst. It has been found, however, that when attempts are made to hydrogenate aromatic nitriles at essentially the same reaction conditions and in the presence of the same type of cobalt catalyst, undesirable side reaction products are produced resulting in comparatively poor yields of the desired aromatic amines. Thus, in the hydrogenation of, for example, isophthalonitrile to metaxylylenecliamine, considerable quantities of the undesirable B-methylbenzylamine are produced by hydrogenolysis at relatively moderate hydrogenation conditions.
It has now been found that aromatic nitriles can be hydrogenated to produce the corresponding amines in high yields with a minimum amount of undesirable side reactions by employing a hydrogenation catalyst containing cobalt and over percent by weight of nickel, based upon the total weight of the cobalt and nickel present. It has been discovered that the presence of nickel in the hydrogenation catalysts considerably suppresses the formation of undesirable reaction products, thus leading to high purity amine products.
According to the present process, at least one aromatic nitrite containing at least one cyano radical all directly attached to the aromatic nucleus and attached to nonadjacent carbon atoms of the aromatic nucleus, is contacted with hydrogen and ammonia at a temperature of from about 100 to 400 F. and at a superatmospheric pressure in the presence of a nickel and cobalt catalyst wherein the weight ratio of the nickel to the cobalt in said catalyst is in the range of from 1:9 to :1. The resulting reaction product is comprised essentially of the amine or amines corresponding to the aromatic nitrile or nitriles present in the initial feed.
As noted above, the aromatic nitriles comprising the feed of subject process are aromatic mono and polynitriles wherein all cyano radicals are directly attached to the aromatic nucleus, and in the case of polynitriles, directly attached to nonadjacent carbon atoms of the aromatic nucleus. Although polynitriles having cyano radicals attached to adjacent carbon atoms of the aromatic nucleus, such as ortho aromatic dinitriles, can be hydrogenated by the present process, yields of the corresponding polyamine are generally so low and side reactions so prevalent that the reaction is completely unattractive from a practical point of view. Illustrative of the basic or unsubstituted compounds contemplated within the scope of the aromatic nitriles are such compounds as benzonitrile, isophthalonitrile, terephthalonitrile, 1,3,5-
tricyanobenzene as well as the polynuclear analogs thereof.
In addition to the cyano radicals, the aromatic nitriles of the feed may have additional substituents, such as alkyl (methyl, ethyl, propyl, butyl, etc.), amide, ester groups and the like. In such compounds, the main requirement is that they are relatively inert during hydrogenation under the conditions of the present process. Examples of such compounds are the isomeric tolunitriles, cyanoethylbenzenes, dicyanotoluenes, and dimethylterephthalonitrile. In these compounds having comparatively inert groups in addition to the cystic radical or radicals, the groups can be attached to the carbon atoms of the aromatic nucleus either in an adjacent or non adjacent manner. Thus, in the case of polynitriles, the additional groups can even be attached between two meta-substituted cyano groups.
The aromatic nitriles comprising the feed can be present either alone or in mixture or in the presence of hydrocarbons. Preferred feeds are isophthalonitrile, terephthalonitrile and mixtures thereof. More preferable still is a feed stock containing isophthalonitrile and/or terephthalonitrile having associated therewith a solvent for the nitrile. Examples of especially desirable solvents are aromatic hydrocarbons, particularly the isomeric Xylenes, dioxane, and aliphatic alcohols. On a Weight ratio basis, the solvent is preferably present in an amount wherein the solvent to nitrile ratio of the feed is in the range of from about 1:1 to about 10:1.
The hydrogenation reaction temperature can vary from about to about 400 F., with a preferred range of from about 200 to 325 F. Similarly, initial pressures can vary from just sufiicient to maintain the ammonia in liquid phase up to a pressure of 5000 p.s.i.g. and higher, generally preferred pressure range being from about 2500 to 3500 p.s.i.g. The space rate can vary over the range of from about 0.05 to 0.3 pound of nitrile per pound of catalyst per hour. The amount of hydrogen employed can vary over a range of from about 2 to 10 or more mols of hydrogen per mol of nitrile.
The catalyst employed in the subject process is one containing both nickel and cobalt wherein the weight ratio of nickel to cobalt lies in the range of from about 1:9 to 15:1, and preferably, from about 1:4 to 4:1. Both the cobalt and the nickel must be in the form of the metal since it has been found that catalysts containing the oxides or sulfides of these metals require operating temperatures that are too high to give even reasonable yields of the desired amine and/or polyamine. It is much preferred that the catalyst be of the unsupported type since supported cobalt-nickel catalysts give rise to considerably lower hydrogenation rates. Various promotors such as silica, thoria, and the like, can also be present if desired. The catalyst can be made by pelleting a mixture of nickel and cobalt oxides, sintering at a temperature of from about 1200 to 1800 P1, and thereafter reducing with hydrogen at a temperature of from about 700 to 900 F. The metal oxides can be technical grade or obtained from the thermal decomposition of carbonates, nitrates, sulfates or the like. In the case of high nickel-content catalysts, sintering temperatures can even be higher than the noted ranges.
The present proces is preferably conducted in continuous, fixed bed operation, i.e., the aromatic nitrile,
aoeaaeo 61 hydrogen, ammonia and solvent are continuously passed through a reaction vessel containing a fixed bed of catalyst. Since the reaction is exothermic, and since the ratio of ammonia to nitrile in the feed bears directly on the product yield (see below), it is preferred that the ammonia (within rather specific limitations discussed below) and/or the hydrogen be employed in excess to aid in maintaining the reaction temperature within the range of from about 100 to 400 F. However, it must be understood that the present process can be conducted by batch, fluid bed or like manner.
As noted hereinbetore, the use of conventional cobalt catal sts in the hydrogenation of, for example, meta and para aromatic dinitriles, leads to hydrogenolysis of the desired diamine with the result that undesirable side reaction products are produced. Thus, in the hydrogenation of isophthalonitrile to metaxylylenediamine, 3- methyl-benzylamine is produced, presumably from the reaction of metaxylylenediamine with hydrogen on the catalyst surface to give a methyl group and ammonia. To show the effect of nickel in reducing this hydrogenolysis, two different hydrogenations of isophthalonitrile were made under identical conditions, the difierence being that Run 1 used a catalyst of cobalt and Run 2 used a nickel-cobalt catalyst having a metals weight ratio of 1:1. Both catalysts were made from technical grade oxides. The finely divided oxide or oxides were mixed in the indicated proportions, pelleted with a lubricant, sintered at about 1600 F. and reduced with hydrogen at about 750 to 900 F. In both hydrogenations (conducted in an autoclave), the pressure was 3000 p.s.i.g., the temperature was 325 F., the reaction time was 3 hours, and the weight ratio of isophthalonitrile:paraxylene:amrnonia was 26:42:32. The results of Runs 1 and 2 are shown in Table I below. The term MXDA refers to the compound rnetaxylylenediamine.
From the above tabie, it can be seen that under identical hydrogenation conditions that the process employing the nickel-cobalt catalyst produced considerably less ES-methylbenzylamine than the process using a straight cobalt catalyst. The amount of polymer produced is also only about one-half as much. The polymer is apparently a byproduct of hydrogenolysis or may also be formed by independent reactions of met-axylylenediamine, isophthalonitrile, or intermediate hydrogenation products and appears as a heavy bottoms fraction upon product distillation.
For optimum yields upon hydrogenation, it has been found that the ratio of nickel to cobalt in the catalyst has a direct relationship to the minimum required ratio of ammonia to nitrile in the feed. Thus, it has been found that, as the nickel-cobalt ratio of the catalyst increases, the ratio of ammonia to nitrile of the feed should also increase in order to maintain high yields of the diamine. The results of numerous hydrogenations showing both the effectiveness of the process of the present invention and the effect of the ammonia to nitrile with varying nickel to cobalt ratios in the catalyst are summarized in Table II below. In all of the runs, the finely divided oxides were mixed in the indicated proportions, pelleted with a lubricant, sintered at about 1600 F. and reduced with hydrogen at about 750 to 900 F. In all of the runs indicated, isophthalonitrile, paraxylene and ammonia (in the proportions shown on the table) were passed into an autoclave charged with the catalyst. The
autoclave was heated to 250 F., hydrogen was added to pressure of 3200 p.s.i.g., the mixture was agitated and hydrogenation was conducted by repressuring with hydrogen when the pressure dropped to 2800 p.s.i.g. All products were analyzed by distillation. The letters IviXDA and IIN appearing in the table represent metaxylylenediarnine and isophthalonitrile, respectively.
TABLE II Rate, a. Wei ht ratios Moi per- Ru Catalyst IPN/cc. IPNzxylene: ce t, No. cat/hr. NH; MXDA yield 3 75% 00-25% Ni..." 2.0 27:47:26 92. 2 75% 00-25% Ni..-" 1.6 z 91. 7 75% 00-25% Ni 1. 9 95. 6 50% 00-50% Ni 3. 0 92. 4 50% 00-50% Ni 1.9 94.0 25% 004.5% Ni- 2. 3 s 25% 00-75% 1. 2 90.6 25% 00-75% Ni 0. 76 93. 9
From the results summarized in the above table, it can be seen that high yields of metaxylylenediamine were realized by employing nickel-cobalt catalysts over relativeiy wide variances in nickel-cobalt weight ratios. These data also show the desirability of increasing the ratio of ammonia to dinitrile in the feed as the nickel content of the catalyst increases. Thus, in Runs 3, 4 and 5, wherein a catalyst having a NizCo weight ratio of 1:3 was employed, it can be seen that metaxylylene diamine yields increase as the ammonia-isophthalonitrile ratio increases from approximately 1:1 (Run 3) to slightly over 2:1 (Runs 4 and 5). The same type of result is shown by Runs 6 and 7 where the Ni:Co ratio is 1:1 and the yield increases from 92.4 to 94.0 as the NHyIPN ratio increases from about 1:1 to 2:1. The effect of this latter ratio with increasing nickel content of the catalyst is shown in an even more pronounced manner by the results of Runs 8, 9 and 10 where the catalyst employed in the hydrogenation reaction had a nickel to cobalt weight ratio of 3:1. It can be seen that at an approximate 1:1 NH :IPN ratio, the metaxylylenediamine yield was only 84.8 (Run 8); at a feed ratio of about 2.5 :1 the yield increased to 90.6 and at an NH zlPN ratio of about 5:1, the yield increased to a high 93.9.
The hydrogenation reaction of the present invention is conducted at a temperature of from about to 400 F., and preferably from about 200 to 325 F. At temperatures below about F., the reaction rate is too slow to be commercially attractive. At temperatures above about 350 F., undesirable hydrogenolysis of the amine product begins to occur and reaches appreciable amounts above 400 F. Although this reaction is particularly prevalent with cobalt catalysts even under moderate conditions (as shown in Table I), it also occurs to a lesser degree with nickel-cobalt catalysts at temperatures above about 350 F. This effect is shown by the hydrogenation runs summarized in Table III. All catalysts were made and the conditions the same as the hydrogenation operations described in Table II except where specific conditions are here described or shown in Table III. The catalysts used in the runs indicated in Table III all had nickel to cobalt weight ratios of 1:1 and ammonia to isophthalonitrile weight ratios of 1:1 and the reactions were conducted under a pressure of 3000 p.s.i.g.
From the results of the runs shown in Table III, it can be seen that both hydrogenolysis and polymer formation begin to occur in relatively appreciable quantity at 400 F. It is apparent that a preferred reaction temperature range lies from about 200 to 325 F. However, in a continuous fixed bed operation, the hydrogenolysis and polymer formation will be somewhat less than the autoclave runs shown in Table III inasmuch as reactantcatalyst contact times will be much shorter.
The hydrogenation process of the present invention is primarily directed to the hydrogenation of aromatic nitriles inasmuch as it has been found that nickel-cobalt catalysts are not as effective in hydrogenating aliphatic nitriles as cobalt catalysts. Thus, it was found that in the hydrogenation of adiponitrile, catalysts of high nickel content gave low yields of hexamethylenediamine even when using high ammonia to nitrile feed ratios. This was in distinct contrast to the above-described high yields of, for example, metaxylylenediamine obtained from isophthalonitrile with the same catalyst and similar reaction conditions.
I claim:
1. A process for reducing a mononuclear aromatic nitrile to an amine, wherein said aromatic nitrile has at least one cyano group directly attached to the aromatic nucleus in other than ortho relationship to other cyano groups so attached and is otherwise unsubstituted, which comprises reacting said nitrile with hydrogen and ammonia at a temperature of from about 100 to 400 F.
under superatmospheric pressure in the presence of a. cobalt-nickel metal catalyst, wherein the weight ratio of nickel to cobalt of said catalyst lies in the range from about 1:9 to 15:1.
2. The process of claim 1 wherein the weight ratio of ammonia to nitrile is maintained in the range of about 1:1 to 10:1.
3. The process according to claim 1 wherein said nitrile is dissolved in an organic solvent selected from the group consisting of aromatic hydrocarbons, dioxane, and aliphatic alcohols, and wherein the ratio of solvent to nitrile is in the range of from about 1:1 to about 10: 1.
4. The process according to claim 1 wherein the temperature is from about 200 to 325 F.
5. The process according to claim 2 wherein said aromatic nitrile is isophthalonitrile.
References Cited in the file of this patent UNITED STATES PATENTS 2,160,578 Schmidt et al May 30, 1939 2,166,971 Schmidt et a1 July 25, 1939 2,449,036 Grunfeld Sept. 7, 1948 2,773,902 Heaton Dec. 11, 1956 2,844,631 Wilkes July 22, 1958 FOREIGN PATENTS 356,731 Great Britain Sept. 1, 1931

Claims (1)

1. A PROCESS FOR REDUCING A MONONUCLEAR AROMATIC NITRILE TO AN AMINE, WHEREIN SAID AROMATIC NITRILE HAS AT LEAST ONE CYANO GROUP DIRECTLY ATTACHED TO THE AROMATIC NUCLEUS IN OTHER THAN ORTHO RELATIONSHIP TO OTHER CYANO GROUPS SO ATTACHED AND IS OTHERWISE UNSUBSTITUTED, WHICH COMPRISES REACTING SAID NITRILE WITH HYDROGEN AND AMMONIA AT A TEMPERATURE OF FROM ABOUT 100* TO 400*F. UNDER SUPERATMOSPHERIC PRESSURE IN THE PRESENCE OF A COBALT-NICKEL METAL CATALYST, WHEREIN THE WEIGHT RATIO OF NICKEL TO COBALT OF SAID CATALYST LIES IN THE RANGE FROM ABOUT 1:9 TO 15:1.
US741233A 1958-06-11 1958-06-11 Hydrogenation of aromatic nitriles Expired - Lifetime US3069469A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US741233A US3069469A (en) 1958-06-11 1958-06-11 Hydrogenation of aromatic nitriles

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US741233A US3069469A (en) 1958-06-11 1958-06-11 Hydrogenation of aromatic nitriles

Publications (1)

Publication Number Publication Date
US3069469A true US3069469A (en) 1962-12-18

Family

ID=24979885

Family Applications (1)

Application Number Title Priority Date Filing Date
US741233A Expired - Lifetime US3069469A (en) 1958-06-11 1958-06-11 Hydrogenation of aromatic nitriles

Country Status (1)

Country Link
US (1) US3069469A (en)

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3255248A (en) * 1959-03-18 1966-06-07 Basf Ag Catalytic hydrogenation of organic nitrogenous carbon compounds to amines
US3528857A (en) * 1966-09-02 1970-09-15 Leesona Corp Electrochemical device comprising an electrode containing nickel-cobalt spinel
US4163025A (en) * 1975-01-16 1979-07-31 Miles Laboratories, Inc. Process for the production of benzylamine and dibenzylamine
US4186146A (en) * 1979-02-01 1980-01-29 Suntech, Inc. Hydrogenation of aromatic nitriles to primary amines
DE3003730A1 (en) * 1979-02-01 1980-08-14 Suntech METHOD FOR HYDROGENATING AROMATIC DINITRILES
US4973746A (en) * 1988-10-24 1990-11-27 General Electric Company Process for converting pet scrap to diamine monomers
EP1279661A1 (en) * 2001-07-16 2003-01-29 Mitsubishi Gas Chemical Company, Inc. Method for producing high purity xylylenediamine
US20060258889A1 (en) * 2003-09-10 2006-11-16 Basf Aktiengesellschaft Method for the production of diaminoxylene by continuous hydrogenation of liquid phthalonitrile
US20070010693A1 (en) * 2003-09-10 2007-01-11 Basf Aktiengesellschaft Method for producing xylylenediamine (xda)
US20070027345A1 (en) * 2003-09-10 2007-02-01 Basf Aktiengesellschaft Method for the production of diaminoxylene by continuous hydrogenation of liquid phthalonitrile
US20080262266A1 (en) * 2005-09-24 2008-10-23 Basf Se Method for the Production of Xylyendiamine
US7728174B2 (en) 2005-08-02 2010-06-01 Basf Se Continuous hydrogenation processes for the preparation of xylylenediamines

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB356731A (en) * 1930-03-01 1931-09-01 Ig Farbenindustrie Ag Improvements in the catalytic hydrogenation of esters of aliphatic carboxylic acids
US2160578A (en) * 1933-05-18 1939-05-30 Ig Farbenindustrie Ag Production of aliphatic amines
US2166971A (en) * 1932-09-14 1939-07-25 Ig Farbenindustrie Ag Production of amines
US2449036A (en) * 1939-11-02 1948-09-07 Grunfeld Maximilien Manufacture of primary amines
US2773902A (en) * 1954-05-10 1956-12-11 California Research Corp Hydrogenation of phthalonitriles
US2844631A (en) * 1956-03-30 1958-07-22 California Research Corp Di (meta-xylylene) triamine

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB356731A (en) * 1930-03-01 1931-09-01 Ig Farbenindustrie Ag Improvements in the catalytic hydrogenation of esters of aliphatic carboxylic acids
US2166971A (en) * 1932-09-14 1939-07-25 Ig Farbenindustrie Ag Production of amines
US2160578A (en) * 1933-05-18 1939-05-30 Ig Farbenindustrie Ag Production of aliphatic amines
US2449036A (en) * 1939-11-02 1948-09-07 Grunfeld Maximilien Manufacture of primary amines
US2773902A (en) * 1954-05-10 1956-12-11 California Research Corp Hydrogenation of phthalonitriles
US2844631A (en) * 1956-03-30 1958-07-22 California Research Corp Di (meta-xylylene) triamine

Cited By (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3255248A (en) * 1959-03-18 1966-06-07 Basf Ag Catalytic hydrogenation of organic nitrogenous carbon compounds to amines
US3528857A (en) * 1966-09-02 1970-09-15 Leesona Corp Electrochemical device comprising an electrode containing nickel-cobalt spinel
US4163025A (en) * 1975-01-16 1979-07-31 Miles Laboratories, Inc. Process for the production of benzylamine and dibenzylamine
US4186146A (en) * 1979-02-01 1980-01-29 Suntech, Inc. Hydrogenation of aromatic nitriles to primary amines
DE3003730A1 (en) * 1979-02-01 1980-08-14 Suntech METHOD FOR HYDROGENATING AROMATIC DINITRILES
US4973746A (en) * 1988-10-24 1990-11-27 General Electric Company Process for converting pet scrap to diamine monomers
EP1279661A1 (en) * 2001-07-16 2003-01-29 Mitsubishi Gas Chemical Company, Inc. Method for producing high purity xylylenediamine
US6646163B2 (en) 2001-07-16 2003-11-11 Mitsubishi Gas Chemical Company, Inc. Method for producing high purity xylylenediamine
US20060258889A1 (en) * 2003-09-10 2006-11-16 Basf Aktiengesellschaft Method for the production of diaminoxylene by continuous hydrogenation of liquid phthalonitrile
US20070010693A1 (en) * 2003-09-10 2007-01-11 Basf Aktiengesellschaft Method for producing xylylenediamine (xda)
US20070027345A1 (en) * 2003-09-10 2007-02-01 Basf Aktiengesellschaft Method for the production of diaminoxylene by continuous hydrogenation of liquid phthalonitrile
US7323597B2 (en) 2003-09-10 2008-01-29 Basf Aktiengesellschaft Method for the production of diaminoxylene by continuous hydrogenation of liquid phthalonitrile
US7339080B2 (en) 2003-09-10 2008-03-04 Basf Aktiengesellschaft Method for the production of diaminoxylene by continuous hydrogenation of liquid phthalonitrile
US7368610B2 (en) 2003-09-10 2008-05-06 Basf Aktiengesellschaft Preparation of xylylenediamine (XDA)
US7728174B2 (en) 2005-08-02 2010-06-01 Basf Se Continuous hydrogenation processes for the preparation of xylylenediamines
US20080262266A1 (en) * 2005-09-24 2008-10-23 Basf Se Method for the Production of Xylyendiamine

Similar Documents

Publication Publication Date Title
US3069469A (en) Hydrogenation of aromatic nitriles
US3673251A (en) Process for the catalytic reductive amination of nitriles
US3255248A (en) Catalytic hydrogenation of organic nitrogenous carbon compounds to amines
US2861995A (en) Process for the conversion of ethanolamine
US2208598A (en) Aliphatic amino-nitriles and process of producing them
EP2114857B1 (en) Method for producing tetraethylenepentamine
CN109689614B (en) In the presence of a catalyst supported on ZrO 2 Method for hydrogenating nitriles in the presence of ruthenium catalysts
WO2008104552A1 (en) Production method for ethyleneamine mixtures
US3136819A (en) Preparation of tertiary aliphatic methyl amines
US2477872A (en) Production of ureas
US20040015016A1 (en) Preparation of secondary amines
US3418375A (en) Preparation of trimethylhexamethylenediamine
US2381472A (en) Production of organic compounds containing nitrogen
WO2014131620A1 (en) Method for producing eda using so2-free hydrocyanic acid
US4248799A (en) Hydrogenation of nitriles in ammonia and water
US4140720A (en) Cobalt hydrogenation catalyst activation
US4186146A (en) Hydrogenation of aromatic nitriles to primary amines
US2532277A (en) 1, 6 hexanediamine derivatives
US3896174A (en) Catalytic hydrogenation of unsaturated dinitriles employing ruthenium, nickel or mixture thereof as catalytic agent
US4320091A (en) Apparatus for two stage catalytic hydrogenation of olefinically unsaturated dinitriles
US3962337A (en) Hydrogenation of unsaturated dinitriles for employing palladium and ruthenium catalyst in aqueous tertiary alkanol
US3697578A (en) Process for preparing 3-pentene nitrile
US3898286A (en) Catalytic hydrogenation of unsaturated dinitriles employing palladium and ruthenium as catalyst
US4215019A (en) Ruthenium-cobalt-gold catalyst for hydrogenation of unsaturated dinitriles
US2225059A (en) Process for catalytic hydrogenation of higher aliphatic nitriles