US2895475A - Container for collecting, storing and dispensing biological fluids - Google Patents

Container for collecting, storing and dispensing biological fluids Download PDF

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Publication number
US2895475A
US2895475A US62597556A US2895475A US 2895475 A US2895475 A US 2895475A US 62597556 A US62597556 A US 62597556A US 2895475 A US2895475 A US 2895475A
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Prior art keywords
container
catheter
collecting
storing
end
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Expired - Lifetime
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Everett L Cole
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Everett L Cole
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    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/54Labware with identification means
    • B01L3/545Labware with identification means for laboratory containers
    • B01L3/5453Labware with identification means for laboratory containers for test tubes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/0045Devices for taking samples of body liquids
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/54Labware with identification means
    • B01L3/545Labware with identification means for laboratory containers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by the preceding groups
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483Physical analysis of biological material
    • G01N33/487Physical analysis of biological material of liquid biological material
    • G01N33/49Blood
    • G01N33/4905Determining clotting time of blood
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/505Containers for the purpose of retaining a material to be analysed, e.g. test tubes flexible containers not provided for above

Description

Filed Dec. 3, 1956 y 21, 1959 E. L. COLE 2,895,475 CONTAINER FOR COLLECTING STORING AND DISPENSING BIOLOGICAL FLUIDS 4 Sheets-Sheet 1 July 21, 1959 L. COLE CONTAINER FOR COLLECTING STORING AND DISPENSING BIOLOGICAL FLUIDS 4 Sheets-Sheet 2 Filed D60. 3. 1956 h m4 my July 21, 1959 2,895,475

E. L. COLE I CONTAINER FOR COLLECTING STORING AND DISPENSING BIOLOGICAL FLUIDS Filed D60. 3 1956 4 Sheets-Sheet 3 INVENTOR.

flare/i L (a/e July 21,1959 E L COLE 2,895,475

CONTAINER FOR COLLECTING STORING'AND DISPENSING BIOLOGICAL FLUIDS Filed Dec. 3, 1956 v I mmvrox Here/1 1. (0/2 4 Sheets-Sheet 4 Unite States atent Patented July 21, 1959 CONTAINER FOR COLLECTING, STORING AND DISPENSING BIOLOGICAL FLUIDS Everett L. Cole, Savannah, Ga.

Application December 3, 1956, Serial No. 625,975

Claims. (Cl. 128-472) My invention relates to improvements in a method and container for collecting, storing and dispensingbiological fluids.

Under present conditions thereare many occasions to isolate small quantities of fluids, such as milk, blood, vaccine, etc. and hold them for indefinite periods of time before carrying out the end use for which the particular fluid was isolated. Some times this involves shipping of the isolated fluid and making analyses thereof at some central laboratory. In other cases the isolation may beat some central point and the end use of the individual quantities isolated may be at widely separated points. My invention contemplates the provision of a novel container for this minimum of susceptibility of contaminationfrom. the exterior, the container beingof such .a onature that its contents may be extracted with the same degree of freedom from exterior contamination. The. containeraembodying my invention is so constructed. as tobezfree of the:usual objections that it is fragile and easily broken. It isalso so constructed that filling and emptying thereof is readily accomplished by asimple device.

It is also a purpose of myinvention to provide in connection with the container of the character above described, a novel method of taking the fiuid into the container and expelling itfrom. the container which is particularly adaptable to the sampling of bloodnand -milk from live animals.

The nature and advantage of my invention will appear more fully from the following description and the accompanying drawings which illustrate a preferred. embodiment of the invention. it shouldbe understood, however, that the description and drawings are illustrative only and are not intended to limit the invention except insofar as it is limited by the claims.

In the drawings:

Figure l is a plan view of a container embodying the invention, showing the container before filling;

Figure 2 is a plan view ofthe container into which the fiuid has been drawn;

Figure 3 is a side view of the container shown in Figure 2, but illustrating the container with adiiferent cathe ter tip;

Figure 4 is a sectional view through the container on the line 4-4 of Figure 2;

Figure 5 is an exteriorview ofthe container showing how it may be sealed in a simple manner by a tab carried thereon;

Figure 6 is .a view looking down at Figure 5;

Figure 7 is a view like Figure 6, illustrating another way of sealing the container;

Figure 8 is an enlarged sectional View of the catheter tip of Figure 3;

Figure 9 is an enlarged sectional view of the catheter tip of Figures l and 2; V

Figure 10 is a plan view of a container modified in certain respects to adapt it particularly for isolation of more than one ingredient of abiological fluid;

Figure 11 is a sectional view taken on the line 1111 of Figure 10;

Figures l2, l3 and 14 are sectional views taken on the lines 12-12, 1313 and 14=14 of Figure 11;

Figure 15 is a sectional view similar to Figure 11, show .ing the container as it appears before segregation of one compartment within it from another;

Figure 16 is a fragmentary sectional view illustrating the extraction of the contents of the container with an ordinary hypodermic needle.

-ofzthe cows udder. These samples are kept separate and properlyidentified so that upon testing in a fully equipped laboratory, any evidence of disease can be traced to the particular source. Some times this testing is done for the purpose of discovering the presence of such diseases as mastitis. The collection of samples in this fashion and their transportation to the central testing laboratory has involved a tremendous amount of work because the samples have heretofore been collected in individual glass test tubes or bottles (usually bottles) which must be stored andtransported and, after emptying them, washed, sterilized, and used over again.

Another example of wide spread need for sample isolation is in the taking of blood tests of animals or human beings and the analyses of the samples of blood collected. In this field as well as in the milk testing field, the practice is to take the individual samples at various places and to carry out the analyses at a central point. Naturally the value of the analyses will depend to a great degree upon the freedom of the samples from exterior contamination or from deterioration between the point of collection and the point of analysis. One of the particular characteristics of my invention is the simplicity by which the exterior contamination is avoided.

According to my invention I prefer to provide a container 10 which is made up of a thin flexible plastic composition. It is desirable but not necessary that the composition be transparent. The particular nature of the composition may, of course, be varied, because there are many of the synthetic resins which will serve for this purpose. A polyethylene resin has been found satisfactory for the particular type of container used in the milk testing field. The container 10 is preferably a flattened tubular body having one end 11 sealed off. The other end of the container is sealed to a tube 12 at 13 so that the tube 12 forms a catheter. The container 10 may have the catheter 12 molded directly with it or inserted. The

catheter is protected by a cap 14. The cap 14 may be provided with a center needle 15 (see Figure 9) to insure that the catheter duct is open. The cap has space 16 for a lubricant. The needle 15 keeps lubricant from entering the duct of the catheter 12 when the cap is withdrawn. In the extraction of milk samples I find I can also.

. inserting the catheter 14 into the teat.

. sample content.

arrange the catheter with a side opening in the manner indicated in Figures 3 and 8 of the drawings, wherein the tip 17 of the catheter is solid and the central passage of the catheter has an end opening 18 at the side of the tip 17 as illustrated. The catheter tube 12 is sufficiently flexible that it may be folded over as indicated in Figures 5,

6 and 7 of the drawings and sealed by a clamping tab 19 that is secured to the container and apertured at 20. The catheter can also be folded and secured by any suitable means 'such as the rubber band 21, shown in Figure 7. The mannerof filling and emptying the container 10 is described'below. The normal shape of the container is fiat or collapsed as it is shown in Figure '1.

In the taking of milk samples, the tube 10 in its flattened air'free condition,.is applied to the teat of the particular quarter. of the c'ows udder to be tested by i The tube may normally fill without assistance, but if the milk does not flow into the ampule from the teat, the technician would ordinarily simply squeeze the teat with his hand, as in normal milking, to causeincrease .in fiow. When sufficient milk for the purpose of the test has been obtained, the catheter 14. is then withdrawnand folded over upon itself 'and' secured by passing it through the tab 19. At

the testing point it is only necessary to clip ofi the catheter 14 or the other end of the container 10 to obtain inthemanner just described, preferably are put up in sets ofz 'four. They can also be furnished singly. It

often happens that only one teat is diseased. All four containers of'a particular set are stamped with a common tainersin the.se't are suitably marked to identify the particular quarterof the udder to which it applies. Preferably each container 10v carries two removable strips 22 and 23 at'the end opposite the catheter. each carry'thesame identification symbol as the container 10.. They are also imprinted to show various teats, the particular teat tested, and they carry a place for the testers name. When the laboratory findings are made these strips are notched to indicate the findings. One strip can be returned to the tester and the other one filed for permanent record, thus avoiding the work and possible mistakes in transferring data to cards. With this arrangement it is also desirable for the tester to keep a book record showing the identification of the particuthat by squeezing the fluid filled portion 32 the seal ca identification number or symbol and the individual con- These strips .4

lar cow tested and identifying the test by the identifica can be packed with these containers and a certain amount of refrigerant soas to keep the samples. in proper condition until they reach the central laboratory.

Referring now to Figureslt) to '16 inclusive, this particularmodification of the container is adapted especially .for thehandling of biologicali fluids and the like where va vaccine on the interior of a container so that when the vaccine is to be used, water or otherfluid-may be Ja added to reconstitute the vaccine to a liquid suspension or? solution for use.

I I The container 30 in Figure 10 is particularly adaptable to this use. This container has The present day insulating containers the two enlarged portions31 and 32 separated by a restriction 33 .'*-In filling the container 30 the vaccine -is placed in the portion 31 thereof and sealed, the seal being made at 33. The container portion 32 can then be filled with water or other fluid in the right amount and sealed off at 35 from the tubular inlet portion 34 which isalso sealed at 36. The seal 33 is weak so be broken.

In use the seal 33 can be broken by applying pressure on the portion 32 so as to mix the fluid and the vaccine in the chamber 31. The vaccine may be withdrawn by means of the needle 37 shown in Figure 16 of the drawings or may be poured out through the restriction 34 as. needed.

Referring now to Figure 17, this figure illustrates a simple effective means to effect the emptying or filling of a container. The container 10 is modified to the extent that its catheter equipped end is enlarged to form a plug or stopper 24 slightly larger than the container 10 in cross section. A substantially rigid transparent tubular shell 25, made of a tough transparent plastic composition, is provided with a tapered mouth 26 to receive the stopper 24. It is also threaded on the exterior to receive a cap 27. The other end of the shell 25 has a collapsible resilient syringe bulb 28. secured thereto by a nipple 29. When the bulb 28 wears out it can be replaced readily. Whenacontainer 10' isinserted in the shell 25 and sealed by the'stopper 24, it can be. subjected to subatmospheric or super-atmospheric pressure by manipulation ofthe bulb 28, to aid in filling or expelling the contents of the container 10'.

Figure 18 illustrates a modified shell 25' which embodies a tapered mouth 26but' which is simplified by leaving off the threaded cap and by making the bulb part -28" integral with the main shell 25. For most purposes thissimplified form of shell is fully satisfactory. With eithe r formof shellthe container 10 may have a bendinvention appear clearly from' the foregoing description.

Having thus described my invention, I claim: 1. Means for collecting and storing fluid samples an the like comprising an elongated flexible tube. having sealed ends and having a catheter integrally joined to one end of the tube incommunication with the interior of said tubefor filling or emptying the tube, a tubular shell having an end opening receiving said container, the container having an enlarged plug at the base of the catheter and the end openingof the shell having a seat for said plug, said shell having a collapsible air bulb joined thereto whereby to apply super-atmospheric or sub-atmospheric pressure to the exterior of a container sealed in said shell by the plug and seat. 2. Means for collecting and storing fluid samples an the like comprising an elongated flexible tube having sealed ends and having a catheter integrally joined to one end of the tube in communication with the interior .of said tube for filling or emptying the tube, said tube having strips projecting from the end opposite the catheter for recording purposes, a tubular shell having an end openlng receiving said container, the container having an enlarged plug at the base of the catheterand the end opening. .of: the shell haying' a' seat'for said plug, said shell having a. collapsible air bulb joined thereto whereby to; apply.super-atmospheric or sub-atmospheric pressure to the exterior of a container sealed in said shell by the plug and seat.

. 3. A container for collecting and storing fluid samples and the like'fcomprising alpair of flexible strips sealed together at theirfside.edgesiandat one end edge and at a polnt spaced inwardly from theother end edge to form: a container, theportions of the strips between said other:end',e'dge and said'inwardly spaced seal forming identification strips for recording purposes, and an elongated bendable tubular catheter-joined to the end of the container opposite the identification strips, said i catheter being in communication with the interior of the container. 5:

4. A cpntainer for collecting and storing fluid samples and the like comprising a pair of flexible strips positioned one against the other with their edges aligned, at least one of said strips having a transverse score line thereon weakening the strip whereby to permit an end portion to be torn therefrom, said strips being sealed together along their side edges and along one end edge and having a transverse seal extending thereacross between the sealed end edge and said score line whereby to provide a sealed pocket therebetween, the portions of the strips between said last named seal and the ends opposite the sealed ends providing identification tabs for recording purposes, and a bendable tubular catheter joined to the sealed ends of said strips and being in communication with the sealed pocket between the strips.

5. Means for collecting and storing fluid samples and the like comprising an elongated flexible tube having sealed ends and having a catheter integrally jointed to one end of the tube in communication with the interior of said tube for filling or emptying the tube, the catheter having its interior passage terminating at the side of the catheter in juxtaposition to the catheter tip, a tubular shell having an end opening receiving said container, the container having an enlarged plug at the base of the catheter and the end opening of the shell having a seat for said plug, said, shell having a collapsible air bulb joined thereto whereby to apply super-atmospheric or sub-atmospheric pressure to the exterior of a container sealed in said shell by the plug and seat.

References Cited in the file of this patent UNITED STATES PATENTS 2,222,267 Schnabel Nov. 19, 1940 2,529,836 Darlington Nov. 14, 1950 2,655,152 Turner et a]. Oct. 13, 1953 2,680,440 Fox June 8, 1954 2,683,456 Pierson July 13, 1954 2,687,130 Cohen Aug. 24, 1954 2,693,189 Ryan Nov. 2, 1954 2,704,076 Larson Mar. 15, 1955 2,731,053 Lockhardt Jan. 17, 1956 2,757,669 Gewecke et al Aug. 7, 1956

US2895475A 1956-12-03 1956-12-03 Container for collecting, storing and dispensing biological fluids Expired - Lifetime US2895475A (en)

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Cited By (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3001403A (en) * 1957-07-01 1961-09-26 William R Kiser Jr Liquid sampler
US3175553A (en) * 1960-03-07 1965-03-30 Memorial Hospital Urine test kit
US3192925A (en) * 1961-08-25 1965-07-06 Cunningham James Robert Disposable syringe device
US3244172A (en) * 1961-11-08 1966-04-05 Brown Ethan Allan Syringe and method of injection
US3279996A (en) * 1962-08-28 1966-10-18 Jr David M Long Polysiloxane carrier for controlled release of drugs and other agents
US3353664A (en) * 1966-08-29 1967-11-21 Pharmaseal Lab Medical instrument package
US3736933A (en) * 1970-12-02 1973-06-05 B Szabo Burstable seamed hypodermic applicators
US3905477A (en) * 1972-03-14 1975-09-16 Union Carbide Corp Tamperproof pouch label
US4018222A (en) * 1975-02-10 1977-04-19 Merck & Co., Inc. Syringe containing frozen vaccine
US4022206A (en) * 1975-08-01 1977-05-10 Merck & Co., Inc. Vaccine delivery system
US4093067A (en) * 1976-11-08 1978-06-06 John P. Glass Mixing package
US4130117A (en) * 1972-09-29 1978-12-19 Eck William F Van Hypodermic syringe
US4198972A (en) * 1978-04-17 1980-04-22 Pharmachem Corporation Blood and blood component storage bags
US4227614A (en) * 1978-09-01 1980-10-14 John P. Glass Packages
US4227611A (en) * 1978-01-27 1980-10-14 John P. Glass Package
US4298119A (en) * 1980-01-11 1981-11-03 Murray Michael L Multiple compartment containers
US4527687A (en) * 1978-01-27 1985-07-09 John P. Glass Package
US4537308A (en) * 1978-09-01 1985-08-27 John P. Glass Rupturable packages
EP0157579A2 (en) * 1984-03-26 1985-10-09 International Health Services Specimen bag and injection assembly
US4608043A (en) * 1984-06-22 1986-08-26 Abbott Laboratories I.V. fluid storage and mixing system
US4690676A (en) * 1983-09-14 1987-09-01 Moulding Jr Thomas S Method of opening a medicine package
US4781696A (en) * 1983-09-14 1988-11-01 Moulding Jr Thomas S Method of dispensing medicine
EP1427531A2 (en) * 2001-09-11 2004-06-16 Iquum, Inc. Sample vessels
US20090247954A1 (en) * 2006-05-03 2009-10-01 Seartouch Llc Closure container for single dose disposable pharmaceutical delivery system
US20100218621A1 (en) * 2003-02-05 2010-09-02 Iquum, Inc. Sample processing methods
FR2949195A1 (en) * 2009-08-24 2011-02-25 Lfb Biomedicaments of therapeutic solution storage pocket
US8187556B2 (en) * 2004-10-29 2012-05-29 Depuy Spine, Inc. Methods and kits for aseptic filing of products
US9662652B2 (en) 2000-12-29 2017-05-30 Chen & Chen, Llc Sample processing device for pretreatment and thermal cycling

Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2222267A (en) * 1937-04-17 1940-11-19 Resistoflex Corp Fire extinguisher
US2529836A (en) * 1950-02-20 1950-11-14 A H Wirz Inc Applicator for treatment of diseases of the udder
US2655152A (en) * 1951-01-30 1953-10-13 Abbott Lab Blood sampling apparatus
US2680440A (en) * 1951-03-27 1954-06-08 Dorothy B Fox Hypodermic unit
US2683456A (en) * 1953-03-02 1954-07-13 Louis A Pierson Rectal medicator
US2687130A (en) * 1950-01-13 1954-08-24 Milton J Cohen Medicament and container therefor
US2693189A (en) * 1950-12-15 1954-11-02 Abbott Lab Venoclysis equipment
US2704076A (en) * 1953-02-20 1955-03-15 Herbert J Larson Dilators
US2731053A (en) * 1953-06-19 1956-01-17 Compule Corp Medical containers and their closures
US2757669A (en) * 1954-07-07 1956-08-07 Baxter Laboratories Inc Apparatus for blood collection and method of using the same

Patent Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2222267A (en) * 1937-04-17 1940-11-19 Resistoflex Corp Fire extinguisher
US2687130A (en) * 1950-01-13 1954-08-24 Milton J Cohen Medicament and container therefor
US2529836A (en) * 1950-02-20 1950-11-14 A H Wirz Inc Applicator for treatment of diseases of the udder
US2693189A (en) * 1950-12-15 1954-11-02 Abbott Lab Venoclysis equipment
US2655152A (en) * 1951-01-30 1953-10-13 Abbott Lab Blood sampling apparatus
US2680440A (en) * 1951-03-27 1954-06-08 Dorothy B Fox Hypodermic unit
US2704076A (en) * 1953-02-20 1955-03-15 Herbert J Larson Dilators
US2683456A (en) * 1953-03-02 1954-07-13 Louis A Pierson Rectal medicator
US2731053A (en) * 1953-06-19 1956-01-17 Compule Corp Medical containers and their closures
US2757669A (en) * 1954-07-07 1956-08-07 Baxter Laboratories Inc Apparatus for blood collection and method of using the same

Cited By (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3001403A (en) * 1957-07-01 1961-09-26 William R Kiser Jr Liquid sampler
US3175553A (en) * 1960-03-07 1965-03-30 Memorial Hospital Urine test kit
US3192925A (en) * 1961-08-25 1965-07-06 Cunningham James Robert Disposable syringe device
US3244172A (en) * 1961-11-08 1966-04-05 Brown Ethan Allan Syringe and method of injection
US3279996A (en) * 1962-08-28 1966-10-18 Jr David M Long Polysiloxane carrier for controlled release of drugs and other agents
US3353664A (en) * 1966-08-29 1967-11-21 Pharmaseal Lab Medical instrument package
US3736933A (en) * 1970-12-02 1973-06-05 B Szabo Burstable seamed hypodermic applicators
US3905477A (en) * 1972-03-14 1975-09-16 Union Carbide Corp Tamperproof pouch label
US4130117A (en) * 1972-09-29 1978-12-19 Eck William F Van Hypodermic syringe
US4018222A (en) * 1975-02-10 1977-04-19 Merck & Co., Inc. Syringe containing frozen vaccine
US4022206A (en) * 1975-08-01 1977-05-10 Merck & Co., Inc. Vaccine delivery system
US4093067A (en) * 1976-11-08 1978-06-06 John P. Glass Mixing package
US4227611A (en) * 1978-01-27 1980-10-14 John P. Glass Package
US4527687A (en) * 1978-01-27 1985-07-09 John P. Glass Package
US4198972A (en) * 1978-04-17 1980-04-22 Pharmachem Corporation Blood and blood component storage bags
US4227614A (en) * 1978-09-01 1980-10-14 John P. Glass Packages
US4537308A (en) * 1978-09-01 1985-08-27 John P. Glass Rupturable packages
US4298119A (en) * 1980-01-11 1981-11-03 Murray Michael L Multiple compartment containers
US4781696A (en) * 1983-09-14 1988-11-01 Moulding Jr Thomas S Method of dispensing medicine
US4690676A (en) * 1983-09-14 1987-09-01 Moulding Jr Thomas S Method of opening a medicine package
EP0157579A2 (en) * 1984-03-26 1985-10-09 International Health Services Specimen bag and injection assembly
EP0157579A3 (en) * 1984-03-26 1987-07-15 International Health Services Specimen bag and injection assembly
US4608043A (en) * 1984-06-22 1986-08-26 Abbott Laboratories I.V. fluid storage and mixing system
US10022722B2 (en) 1998-06-24 2018-07-17 Roche Molecular Systems, Inc. Sample vessels
US20110143968A1 (en) * 1998-06-24 2011-06-16 Iquum, Inc. Sample vessels
US9005551B2 (en) 1998-06-24 2015-04-14 Roche Molecular Systems, Inc. Sample vessels
US9662652B2 (en) 2000-12-29 2017-05-30 Chen & Chen, Llc Sample processing device for pretreatment and thermal cycling
EP1427531B1 (en) * 2001-09-11 2016-10-19 Iquum, Inc. Sample vessels
EP1427531A2 (en) * 2001-09-11 2004-06-16 Iquum, Inc. Sample vessels
US8936933B2 (en) 2003-02-05 2015-01-20 IQumm, Inc. Sample processing methods
US9708599B2 (en) 2003-02-05 2017-07-18 Roche Molecular Systems, Inc. Sample processing methods
US20100218621A1 (en) * 2003-02-05 2010-09-02 Iquum, Inc. Sample processing methods
US8187556B2 (en) * 2004-10-29 2012-05-29 Depuy Spine, Inc. Methods and kits for aseptic filing of products
US20090247954A1 (en) * 2006-05-03 2009-10-01 Seartouch Llc Closure container for single dose disposable pharmaceutical delivery system
US20110196338A1 (en) * 2006-05-03 2011-08-11 Seratouch, Llc Closure container for single dose disposable pharmaceutical delivery system
US7892211B2 (en) * 2006-05-03 2011-02-22 Seratouch, L.L.C. Closure container for single dose disposable pharmaceutical delivery system
WO2011024112A1 (en) * 2009-08-24 2011-03-03 Lfb Biomedicaments Bag for storing a therapeutic solution
US9468585B2 (en) 2009-08-24 2016-10-18 Lfb Biomedicaments Bag for storing a therapeutic solution
FR2949195A1 (en) * 2009-08-24 2011-02-25 Lfb Biomedicaments of therapeutic solution storage pocket
CN102548522A (en) * 2009-08-24 2012-07-04 Lfb生物医药公司 Bag for storing a therapeutic solution
EP2470147B1 (en) 2009-08-24 2015-10-14 Laboratoire Français du Fractionnement et des Biotechnologies Bag for storing a therapeutic solution

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