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Medicament dispensing unit

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Publication number
US2764979A
US2764979A US34770953A US2764979A US 2764979 A US2764979 A US 2764979A US 34770953 A US34770953 A US 34770953A US 2764979 A US2764979 A US 2764979A
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Prior art keywords
ampule
dispensing
needle
barrel
unit
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Henderson Edward
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EDWARD HENDERSON
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EDWARD HENDERSON
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/28Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle
    • A61M5/281Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle using emptying means to expel or eject media, e.g. pistons, deformation of the ampoule, or telescoping of the ampoule
    • A61M5/282Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle using emptying means to expel or eject media, e.g. pistons, deformation of the ampoule, or telescoping of the ampoule by compression of deformable ampoule or carpule wall
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/3145Filters incorporated in syringes

Description

Oct. 2, 1956 E. HENDERSON MEDICAMENT DISPENSING UNIT Filed April 9, 1953 1 INVENTOR du/afd /fefmensv/ ATTORNEYS United States Patent O MEDICAMENT DISPENSING UNIT Edward Henderson, Montclair, N. J. Application April 9, 1956, Serial No. 347,709

3 Claims. (Cl. 12S-216) This invention relates to hypodermic syringe units and in one aspect involves an improvement over my prior Patent No. 2,388,323, issued on November 6, 1945, which shows a unit in which the barrel is made of a plastic or resilient material and in which the needle is sealed either by a diaphragm or by imbedding it into the cap.

This application is a continuation in part of my prior application for U. S. Letters Patent, Serial Number 179,- 944 on Hypodermic Syringe Ampule-Unit, filed August 17, 1950, now abandoned.

Hypodermic syringes of the type commonly used in hospitals comprise a glass barrel having a plunger and a piston. These syringes are relatively bulky and easily broken. They are normally kept empty and sterile and filled when needed and as a practical matter cannot be kept filled for immediate use.

An object of this invention is to provide a disposable unit to be used for hypodermic injections and the dispensing of medicament, such unit being particularly adapted for first aid use, for use in parachute and other military emergency medical kits or Wherever speedy treatment of the sick or injured is important. It' will also be a useful addition to the armamentarium of the practicing physician.

Another object is to provide a unit which will overcome certain objections to disposable units heretofore available. My invention, for example, will reveal immediately upon visual examination that the unit is intact and that the full dose of the drug intended to be used is contained in the unit. It is one of the features of my invention that I combine the advantages of a sealed transparent glass container with-in a resilient barrel made of a compressible material such as one of the ethylene polymers or other suitable plastic.

An additional object is that of furnishing a medicament dispensing unit which will include relatively few parts each individually rugged and simple in construction; such parts being capable of ready manufacture, sterilization and assembly to furnish unitary assemblies which may readily be transported, stored and used.

In the accompanying drawings:

Fig.l is a cross-sectional elevation of a hypodermic syringe unit embodying the present invention;

Fig. 2 is an elevation taken at right angles to Fig. l with the cap in section and showing the cap removed from the syringe so that the syringe is ready for use; and

Fig. 3 is a View similar to Fig. l but showing an alternative form of structure.

Referring more particularly to Figs. 1 and 2 of the drawings, I provide a barrel portion which is preferably tubular in shape and made of a resilient transparent compressible material such as one of the polyvinyl resins. The lower end 11 of the barrel member 10 may be closed by heat sealing or by means of a solvent and an adhesive with pressure. The upper end 12 of the barrel 10 is contained Within a U-channel 14 of the needle assembly 15. The needle assembly is preferably made of metal with a needle 16, a hub portion 17 and 2 a rim 118 forming with an inner rim 19 the U-shaped channel 14. The hub 17 is reduced in size from the rim 18 and is adapted to frictionally engage the inner surface 20 of the cap member 21. The cap member 21 is also provided with a recess 2.2 to house the needle 16.

Mounted Within the barrel 10 is an ampule 25 preferably made of thin transparent glass or other frangible material which will not adversely affect the medicament. Positioned in the hub 17 between the opening 26 of the needle and top of the ampule 25 is a filter 27 made of cotton or other suitable material. The cap 21 fits over the needle 16 and forms pressure contact with the hub 17, thus definitely sealing the needle from the air or from other sources of contamination until the needle is actually ready for use. Due to the resiliency of the barrel 10 the chances of the ampule 25 being broken unintentionally are slight and the entire unit will take yconsiderable abuse without injury.

In assembly, the barrel portionr10 is inserted in the channel 14. and the rims crimped together firmly to hold the needle assembly to the barrel.. The cap is loosely applied and the filter is inserted. The ampule 25, containing the fluid drug 30, is inserted through the end of the barrel and the end 11 of the barrel is sealed. The entire device is then sterilized and the cap tightened by friction. The syringe unit is then ready for immediate use and operated simply by removing the cap, inserting the needle into the tissue and squeezing the' barrel 10 to an extent sufficient to crush the frangible ampule 25 and to allow the liquid to be forced through the filter and out through the needle. The condition and amount of the fluid 30 are readily ascertainable by visible inspection since the barrel 10 and the ampule 25 are transparent.

In Fig. 3 a unit has been shown which is especially useful in connection with ophthalmic solutions where one or more drops are tobe dispensed. In this view the numeral 31 indicates an encasing member formed of suitablevplastic material and the end of which is sealed as at 32. Similar to Fig. 1, this member is formed with a reduced neck portion 33 which may, however, be integral with its body. This neck portion terminates in a discharge mouth or lip suitable for drop by drop dispensing. A cap 34 has a friction fit on this neck and the parts are sterilized so that they will remain in proper condition as long as the cap is mounted upon the neck.

Within the encasing member an ampule 3S' containing a proper solution is disposed. This ampule `is jacketed or surrounded by a casing 36 of fibers. The latter may serve as a filtering medium. Otherwise a lter may be interposed between the ampule and the base of the spout in the manner shown in Fig. l.

In any event when it is desired to employ the device, this may readily be done by simply pressing the encasing member and thus ruptur-ing the contained ampule. Thereupon the cap is dismounted and the discharge end` of the spout or neck is disposed adjacent the surface to receive the solution, As the encasing member is compressed or collapsed, the solution originally within the ampule, and which is now within that member, will be forced through the filtering medium and discharged through the spout.

Thus among others the several objects of the invention as specifically aforenoted are achieved. Obviously numerous changes in construction and rearrangements of the parts might be resorted to without departing from the spirit of the invention as defined by the claims.

I claim:

l. A medicament dispensing unit containing a tubular resilient barrel member having one end thereof closed, a needle assembly including a hypodermic needle, said needle assembly having a pair of walls forming a U- shaped channel engaging the other end` of said barrel member and sealing a transparent frangible ampule containing liquid material Within said barrel member and a lter between said ampule and said needle.

2. A dispensing container for packaging and dispensing fluid preparations comprising: an ampule containing the fluid preparation and made of a material impervious to and unaffected by said uid preparation, said ampule being frangible so that the fluid preparation may bev dispensed therefrom by breaking the ampule; an outer tubular casing completely enclosing and encasing the ampule and made of a exible material impervious to and unaffected by said fluid preparation, said casing being formed with an outwardly projectingdispensing portion having a dispensing aperture extending therethrough and said casing being collapsible whereby said casing may be co1- lapsed to break the frangible ampule and to dispense the fluid preparation through the dispensing aperture; and means providing a filter between said ampule and said dispensing aperture to restrain solid particles of said ampule when broken from passing through said dispensing aperture,

3. A hypodermic assembly for use in packaging and hypodermically dispensing fluid medicaments compiising: an ampule containing the uid medicament and made of a material impervious to and unaffected by said medicament, said ampule being frangible so that the uid medicament may be dispensed therefrom by breaking the ampule; an outer tubular casing completely enclosing and encasing the ampule and made of a exible material impervious to and unaffected by said fluid medicament, said casing having a hypodermic needle with a dispensing aperture extending therethrough communicating with the interior thereof and projecting outwardly therefrom and said casing beingcollapsible whereby said casing may be collapsed to breakthe frangible ampule and to dispense the fluid medicament through the dispensing aperture in the hypodermic needle; and means providing a filter between said ampule and said dispensing aperture to restrain solid particles of said ampule when broken from passing through the dispensing aperture.

References Cited in the le of this patent UNITED STATES PATENTS v730,596 Baker June 9, 1903 1,221,231 sharp Apr. 3, 1917 2,493,416 Negri v Jan. 3, o

FOREIGN PATENTS 22,812 Great Britain ocr. 22, 1904

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Cited By (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3576987A (en) * 1968-11-07 1971-05-04 American Cyanamid Co Chemical lighting device to store, initiate and display chemical light
US4693709A (en) * 1985-04-08 1987-09-15 Sherwood Medical Company Syringe
US4955871A (en) * 1987-04-29 1990-09-11 Path Single-use disposable syringe
US4972623A (en) * 1989-07-03 1990-11-27 Delricco James R Cold illuminated fishing jig
US5181909A (en) * 1991-05-15 1993-01-26 Mcfarlane Richard H Ampule-container medical syringe and methods
US5306277A (en) * 1991-12-23 1994-04-26 Zimmer, Inc. Monomer transfer device
WO2002074373A1 (en) * 2001-03-20 2002-09-26 Aerogen, Inc. Convertible fluid feed system with comformable reservoir and methods
US20050229927A1 (en) * 2004-04-20 2005-10-20 Aerogen, Inc. Ventilation systems and methods employing aerosol generators
US6978941B2 (en) 2001-05-02 2005-12-27 Aerogen, Inc. Base isolated nebulizing device and methods
US7032590B2 (en) 2001-03-20 2006-04-25 Aerogen, Inc. Fluid filled ampoules and methods for their use in aerosolizers
US7040549B2 (en) 1991-04-24 2006-05-09 Aerogen, Inc. Systems and methods for controlling fluid feed to an aerosol generator
US7066398B2 (en) 1999-09-09 2006-06-27 Aerogen, Inc. Aperture plate and methods for its construction and use
US7174888B2 (en) 1995-04-05 2007-02-13 Aerogen, Inc. Liquid dispensing apparatus and methods
US7201167B2 (en) 2004-04-20 2007-04-10 Aerogen, Inc. Method and composition for the treatment of lung surfactant deficiency or dysfunction
US20070170080A1 (en) * 2006-01-26 2007-07-26 Joshua Stopek Medical device package
US20070209659A1 (en) * 1995-04-05 2007-09-13 Aerogen, Inc. Liquid dispensing apparatus and methods
US7290541B2 (en) 2004-04-20 2007-11-06 Aerogen, Inc. Aerosol delivery apparatus and method for pressure-assisted breathing systems
US7322349B2 (en) 2000-05-05 2008-01-29 Aerogen, Inc. Apparatus and methods for the delivery of medicaments to the respiratory system
US7331339B2 (en) 2000-05-05 2008-02-19 Aerogen, Inc. Methods and systems for operating an aerosol generator
US7360536B2 (en) 2002-01-07 2008-04-22 Aerogen, Inc. Devices and methods for nebulizing fluids for inhalation
US20080110773A1 (en) * 2006-11-14 2008-05-15 Greep Darcy W Wearable devices for dispensing flowable agents
US20080128296A1 (en) * 2006-01-26 2008-06-05 Joshua Stopek Medical device package
US20080171972A1 (en) * 2006-10-06 2008-07-17 Stopek Joshua B Medical device package
US20090173808A1 (en) * 2008-01-03 2009-07-09 Hsiu-Chun Chen Airbrush structure
US7600511B2 (en) 2001-11-01 2009-10-13 Novartis Pharma Ag Apparatus and methods for delivery of medicament to a respiratory system
US7628339B2 (en) 1991-04-24 2009-12-08 Novartis Pharma Ag Systems and methods for controlling fluid feed to an aerosol generator
US20100004620A1 (en) * 2006-10-06 2010-01-07 Stopek Joshua B Medical Device Package Including Self-Puncturable Port
US7677467B2 (en) 2002-01-07 2010-03-16 Novartis Pharma Ag Methods and devices for aerosolizing medicament
US7771642B2 (en) 2002-05-20 2010-08-10 Novartis Ag Methods of making an apparatus for providing aerosol for medical treatment
US20100242830A1 (en) * 2007-12-20 2010-09-30 Cooper Technologies Company Explosion Indicators For Use In Explosion-Proof Enclosures With Critical Equipment
US7971588B2 (en) 2000-05-05 2011-07-05 Novartis Ag Methods and systems for operating an aerosol generator
US20110232561A1 (en) * 2007-12-20 2011-09-29 Cooper Technologies Company Indicating Devices and Associated Methods
US8228206B2 (en) 2008-08-18 2012-07-24 Cooper Technologies Company Explosion indicator for explosion-proof enclosures
US8336545B2 (en) 2000-05-05 2012-12-25 Novartis Pharma Ag Methods and systems for operating an aerosol generator
US8616195B2 (en) 2003-07-18 2013-12-31 Novartis Ag Nebuliser for the production of aerosolized medication
US9108211B2 (en) 2005-05-25 2015-08-18 Nektar Therapeutics Vibration systems and methods
US9494476B2 (en) 2007-12-20 2016-11-15 Cooper Technologies Company Indicator device for an enclosure with sealing compound
WO2017182540A1 (en) * 2016-04-21 2017-10-26 Sanofi-Aventis Deutschland Gmbh Container for a liquid medicament

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US730596A (en) * 1902-06-18 1903-06-09 Francis M Baker Syringe.
GB190422812A (en) * 1904-10-22 1905-08-10 Dental Mfg Co Ltd A Capsule Holder and Breaker for use in Administering Anaesthetics.
US1221231A (en) * 1916-05-03 1917-04-03 Bauer & Black Surgical swab.
US2493416A (en) * 1947-07-17 1950-01-03 A Gazzoni & Co Soc Odontalgic device

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US730596A (en) * 1902-06-18 1903-06-09 Francis M Baker Syringe.
GB190422812A (en) * 1904-10-22 1905-08-10 Dental Mfg Co Ltd A Capsule Holder and Breaker for use in Administering Anaesthetics.
US1221231A (en) * 1916-05-03 1917-04-03 Bauer & Black Surgical swab.
US2493416A (en) * 1947-07-17 1950-01-03 A Gazzoni & Co Soc Odontalgic device

Cited By (55)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3576987A (en) * 1968-11-07 1971-05-04 American Cyanamid Co Chemical lighting device to store, initiate and display chemical light
US4693709A (en) * 1985-04-08 1987-09-15 Sherwood Medical Company Syringe
US4955871A (en) * 1987-04-29 1990-09-11 Path Single-use disposable syringe
US4972623A (en) * 1989-07-03 1990-11-27 Delricco James R Cold illuminated fishing jig
US7040549B2 (en) 1991-04-24 2006-05-09 Aerogen, Inc. Systems and methods for controlling fluid feed to an aerosol generator
US7628339B2 (en) 1991-04-24 2009-12-08 Novartis Pharma Ag Systems and methods for controlling fluid feed to an aerosol generator
US5181909A (en) * 1991-05-15 1993-01-26 Mcfarlane Richard H Ampule-container medical syringe and methods
US5306277A (en) * 1991-12-23 1994-04-26 Zimmer, Inc. Monomer transfer device
US8561604B2 (en) 1995-04-05 2013-10-22 Novartis Ag Liquid dispensing apparatus and methods
US20070209659A1 (en) * 1995-04-05 2007-09-13 Aerogen, Inc. Liquid dispensing apparatus and methods
US7174888B2 (en) 1995-04-05 2007-02-13 Aerogen, Inc. Liquid dispensing apparatus and methods
US7066398B2 (en) 1999-09-09 2006-06-27 Aerogen, Inc. Aperture plate and methods for its construction and use
US8398001B2 (en) 1999-09-09 2013-03-19 Novartis Ag Aperture plate and methods for its construction and use
US20070023547A1 (en) * 1999-09-09 2007-02-01 Aerogen, Inc. Aperture plate and methods for its construction and use
US7322349B2 (en) 2000-05-05 2008-01-29 Aerogen, Inc. Apparatus and methods for the delivery of medicaments to the respiratory system
US7331339B2 (en) 2000-05-05 2008-02-19 Aerogen, Inc. Methods and systems for operating an aerosol generator
US7748377B2 (en) 2000-05-05 2010-07-06 Novartis Ag Methods and systems for operating an aerosol generator
US7971588B2 (en) 2000-05-05 2011-07-05 Novartis Ag Methods and systems for operating an aerosol generator
US8336545B2 (en) 2000-05-05 2012-12-25 Novartis Pharma Ag Methods and systems for operating an aerosol generator
US7100600B2 (en) * 2001-03-20 2006-09-05 Aerogen, Inc. Fluid filled ampoules and methods for their use in aerosolizers
US6948491B2 (en) 2001-03-20 2005-09-27 Aerogen, Inc. Convertible fluid feed system with comformable reservoir and methods
US7032590B2 (en) 2001-03-20 2006-04-25 Aerogen, Inc. Fluid filled ampoules and methods for their use in aerosolizers
US8196573B2 (en) 2001-03-20 2012-06-12 Novartis Ag Methods and systems for operating an aerosol generator
US7195011B2 (en) 2001-03-20 2007-03-27 Aerogen, Inc. Convertible fluid feed system with comformable reservoir and methods
WO2002074373A1 (en) * 2001-03-20 2002-09-26 Aerogen, Inc. Convertible fluid feed system with comformable reservoir and methods
US7104463B2 (en) 2001-05-02 2006-09-12 Aerogen, Inc. Base isolated nebulizing device and methods
US6978941B2 (en) 2001-05-02 2005-12-27 Aerogen, Inc. Base isolated nebulizing device and methods
US7600511B2 (en) 2001-11-01 2009-10-13 Novartis Pharma Ag Apparatus and methods for delivery of medicament to a respiratory system
US7677467B2 (en) 2002-01-07 2010-03-16 Novartis Pharma Ag Methods and devices for aerosolizing medicament
US7360536B2 (en) 2002-01-07 2008-04-22 Aerogen, Inc. Devices and methods for nebulizing fluids for inhalation
US8539944B2 (en) 2002-01-07 2013-09-24 Novartis Ag Devices and methods for nebulizing fluids for inhalation
US7771642B2 (en) 2002-05-20 2010-08-10 Novartis Ag Methods of making an apparatus for providing aerosol for medical treatment
US8616195B2 (en) 2003-07-18 2013-12-31 Novartis Ag Nebuliser for the production of aerosolized medication
US20050229927A1 (en) * 2004-04-20 2005-10-20 Aerogen, Inc. Ventilation systems and methods employing aerosol generators
US7290541B2 (en) 2004-04-20 2007-11-06 Aerogen, Inc. Aerosol delivery apparatus and method for pressure-assisted breathing systems
US7201167B2 (en) 2004-04-20 2007-04-10 Aerogen, Inc. Method and composition for the treatment of lung surfactant deficiency or dysfunction
US7267121B2 (en) 2004-04-20 2007-09-11 Aerogen, Inc. Aerosol delivery apparatus and method for pressure-assisted breathing systems
US7946291B2 (en) 2004-04-20 2011-05-24 Novartis Ag Ventilation systems and methods employing aerosol generators
US9108211B2 (en) 2005-05-25 2015-08-18 Nektar Therapeutics Vibration systems and methods
US9364215B2 (en) 2006-01-26 2016-06-14 Covidien Lp Medical device package
US20080128296A1 (en) * 2006-01-26 2008-06-05 Joshua Stopek Medical device package
JP2007195967A (en) * 2006-01-26 2007-08-09 Tyco Healthcare Group Lp Medical device package
US20070170080A1 (en) * 2006-01-26 2007-07-26 Joshua Stopek Medical device package
US20080171972A1 (en) * 2006-10-06 2008-07-17 Stopek Joshua B Medical device package
US20100004620A1 (en) * 2006-10-06 2010-01-07 Stopek Joshua B Medical Device Package Including Self-Puncturable Port
US8061520B2 (en) 2006-10-06 2011-11-22 Tyco Healthcare Group Lp Medical device package including self-puncturable port
US20080110773A1 (en) * 2006-11-14 2008-05-15 Greep Darcy W Wearable devices for dispensing flowable agents
US20110232561A1 (en) * 2007-12-20 2011-09-29 Cooper Technologies Company Indicating Devices and Associated Methods
US7975527B2 (en) * 2007-12-20 2011-07-12 Cooper Technologies Company Explosion indicators for use in explosion-proof enclosures with critical equipment
US20100242830A1 (en) * 2007-12-20 2010-09-30 Cooper Technologies Company Explosion Indicators For Use In Explosion-Proof Enclosures With Critical Equipment
US9111425B2 (en) 2007-12-20 2015-08-18 Cooper Technologies Company Indicating devices and associated methods
US9494476B2 (en) 2007-12-20 2016-11-15 Cooper Technologies Company Indicator device for an enclosure with sealing compound
US20090173808A1 (en) * 2008-01-03 2009-07-09 Hsiu-Chun Chen Airbrush structure
US8228206B2 (en) 2008-08-18 2012-07-24 Cooper Technologies Company Explosion indicator for explosion-proof enclosures
WO2017182540A1 (en) * 2016-04-21 2017-10-26 Sanofi-Aventis Deutschland Gmbh Container for a liquid medicament

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