US2746264A - Miniature cooling unit - Google Patents

Miniature cooling unit Download PDF

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US2746264A
US2746264A US368760A US36876053A US2746264A US 2746264 A US2746264 A US 2746264A US 368760 A US368760 A US 368760A US 36876053 A US36876053 A US 36876053A US 2746264 A US2746264 A US 2746264A
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refrigerant
chamber
case
capsule
metering
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US368760A
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Frederick G Keyes
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ALFRED BICKNELL ASSOCIATES Inc
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ALFRED BICKNELL ASSOCIATES Inc
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M19/00Local anaesthesia; Hypothermia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/02Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/42Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for desensitising skin, for protruding skin to facilitate piercing, or for locating point where body is to be pierced
    • A61M5/422Desensitising skin
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F25REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
    • F25DREFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
    • F25D3/00Devices using other cold materials; Devices using cold-storage bodies
    • F25D3/10Devices using other cold materials; Devices using cold-storage bodies using liquefied gases, e.g. liquid air
    • F25D3/107Devices using other cold materials; Devices using cold-storage bodies using liquefied gases, e.g. liquid air portable, i.e. adapted to be carried personally
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150053Details for enhanced collection of blood or interstitial fluid at the sample site, e.g. by applying compression, heat, vibration, ultrasound, suction or vacuum to tissue; for reduction of pain or discomfort; Skin piercing elements, e.g. blades, needles, lancets or canulas, with adjustable piercing speed
    • A61B5/150106Means for reducing pain or discomfort applied before puncturing; desensitising the skin at the location where body is to be pierced
    • A61B5/150129Means for reducing pain or discomfort applied before puncturing; desensitising the skin at the location where body is to be pierced by cooling
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/36General characteristics of the apparatus related to heating or cooling
    • A61M2205/3606General characteristics of the apparatus related to heating or cooling cooled

Definitions

  • the present invention relates to a miniature refrigeration unit and in particular to a miniature portable refrigeration unit especially adapted for use in desensitizing skin regions in preparation for a hypodermic injection or the like.
  • Hypodermic injections may be made substantially painless by bringing the temperature of the skin surrounding the area of the injection down to a temperature between freezing and 40 degrees Fahrenheit. While devices exist which will freeze the skin for minor operations, such devices are not useful for this purpose since freezing the skin results in an increase in pain and sensation after the freezing wears off. If however the skin is chilled to a temperature just above the freezing point, then the procedure is effective to eliminate all sensation both during and after the injecting.
  • Fig. 1 shows the external appearance of the device.
  • Fig. 2 is a sectional view taken along the major axis of the device on the line 2-2 of Fig. 1.
  • Fig. 3 is a sectional view on an enlarged scale of the lower end portion of the device shown in Figs. 1 and 2, showing the heat exchange chamber and contact cooling surface of the device, and
  • Fig. 4 is a cross-sectional view of the heat exchange chamber, taken on the line 4-4 of Fig. 3.
  • the case 1 is made in four sections 2, 3, 4, and 5, which are attached together by overlapping threaded flanges.
  • the cap 2 fitting over the body section 3 provides a chamber 9 containing a disposable metal capsule 7 of refrigerant.
  • a hollow pointed needle 11 extends through the end of the refrigerant capsule and the capsule itself is firmly seated on the rubber ring 13 surrounding the needle. This needle extends downward into section 4 of the case to a small chamber 14 sealed by the O-ring 15.
  • Refrigerant which passes through the hollow pointed needle into this chamber is filtered by the filter 19 which separates the chamber 14 from the passage 21 leading to the metering valve.
  • This valve which automatically supplies the correct amount of refrigerant consists of a valve member which in this case is a spool 22 fitted so as to slide in a cylindrical chamber or cavity 20 in section 4 of the casing, and normally urged toward the head of the unit by a coil spring 24.
  • a valve member of rectangular cross section would be equally acceptable, however.
  • passage of the refrigerant through the duct 21 is blocked by the flange 23 of this spool. Further sealing of the refrigerant is effected by the O-rings 25 and 26 on either side of the orifice leading to the duct 21.
  • An escape duct 27 is provided through the case to the part of the cylindrical chamber containing the spring to prevent a building up of pressure by any refrigerant passing the O-ring 25.
  • valve member The central part of the valve member is cut away to provide a recess forming a metering chamber 29 which may be loaded with refrigerant by forcing back the head of the instrument 50 causing the spool 22 to compress the spring 24 until this metering chamber is opposite the inlet port from the supply duct 21.
  • this metering chamber or recess leads to an outlet port supplying the delivery duct 31 in the case.
  • This duct in turn leads to the annular groove 33 cut into the lower flange 32 of the spool 22 which opens to the delivery duct 37 carrying refrigerant to the cooling head 50 of the instrument.
  • This lower flange is supplied with the O-rings 35 and 36 to prevent leakage.
  • the delivery duct 37 is surrounded by an insulating member 38 which serves to minimize transfer of heat from the body of the instrument to the cooling head 54) and to firmly attach the exchanger 50 with the spool 22. Contact between this insulating member and the spool is further minimized by use of the washer 40.
  • the cooling head 50 construction of which will be more fully described presently is slidably fitted in the insulating member 41 which a protective sleeve preventing heat transfer between the cooling head 50 and the end section 5 of the case. Refrigerant which has expanded through the head 50 is permitted to escape through the outlet 43 in the insulating member and then through the outlet 45 in the case.
  • the cooling head 50 is shown in section in Fig. 3. It consists of a hollow cylindrical shell 53 having a relatively thick flat end plate 54 constructed of conductive material. The inside of this shell contains a spiral heat exchange chamber formed by a conductive vane 47 firmly attached to the end plate 54 and extending to but not attached to the opposite end of the chamber.
  • the refrigerant line 57 through which the refrigerant is introduced to this chamber is an extension of the supply line 37 and is attached to the spiral vane. The refrigerant is released at the end and the expanding gas passes back along the spiral heat exchange chamber and the delivery line 57 to the outlet 60, which in turn leads to the exhaust port 43 described above.
  • the operator When the instrument is to be used, as, for example in anesthetizing a small area of a patients skin, the operator simply presses the head of the instrument 50 against a convenient surface, thus forcing the head and the spool back against the spring 24 and positioning the metering chamber 29 opposite the inlet port from the supply duct 21 whereupon a charge of refrigerant is admitted into the metering chamber. Pressure on the instrument is then released and the spring restores the parts to the position shown in Fig. 2 whereupon the refrigerant is released through the outlet port to the delivery line 31 and into the heat exchanging head 50.
  • the refrigerant In passing through the heat exchange chamber described above, the refrigerant is vaporized and the vapor expands through this chamber thereby producing a rapid cooling effect both by absorption of the latent heat of vaporization and by expansion.
  • the size of the metering chamber is such as to provide a quantity of refrigerant suflicient to cool the face of the instrument to a temperature of about 33 F.
  • this device is convenient to handle since the operator requires only one free hand and is economical since the metering chamber supplies only the amount of refrigerant actually needed. As heretofore noted it is particularly useful for mild local anesthesia for hypodermic injections. While the device has been described in terms of a single embodiment it will be understood that considerable variation in the actual construction may be made within the scope of this invention.
  • a refrigeration unit comprising a case, a detachable capsule of compressed refrigerant, means for tapping said capsule, valving means for periodically releasing a metered amount of the refrigerant, and a counterfiow heat exchanger for the refrigerant comprising a spiral chamber formed by a spiral vane attached to a flat cooling end surface wherein the refrigerant supply is carried through said spiral chamber in a duct attached to the vane and the expanding gas escaping through the spiral cools the incoming refrigerant.
  • a refrigeration unit comprising a case, a detachable capsule of refrigerant, means for tapping said capsule, a valve member slidably fitted to a chamber in the case and having a metering recess, said case having ducting means with an inlet port and an outlet port to the chamber separated by a distance greater than the length of the metering recess, spring loading means for maintaining the metering recess in registration with the outlet port, a heat exchanger comprising a single spiral expansion chamber for the refrigerant, ducting means connecting the tapping means with the inlet port and the outlet port with the heat exchanger, and means for positioning the metering recess opposite the inlet port.
  • a refrigeration unit comprising a case, a removable cap fitted to the case providing a chamber for a refrigerant capsule, a hollow needle surrounded by a compressible sealing member in said chamber and acting in cooperation with the cap to tap the capsule, a filtering member, a duct leading from the head of the needle to the filtering member, a multiposition valve .member slidably fitted to a chamber within the case, a metering storage recess, ducting means leading from the filter to the metering recess when the valve member is in one position, an expansion chamber for the refrigerant, and ducting means leading from the storage recess to the expansion chamber when the valve is in a second position.
  • a refrigeration unit comprising a case, a detachable capsule of refrigerant, means for tapping said capsule, a valve member movably fitted to a chamber within said case whereby a metering chamber for the refrigerant is formed between the valve member and a surface of said case chamber, an expansion chamber having a surface to be cooled, a supply duct'from the tapping means to an inlet port for the metering chamber, a delivery duct from an outlet port from the metering chamber to the expansion chamber, means for moving the valve member to effect flow of a charge from the inlet port to the metering chamber, and means for positioning the valve member to close the valve and permit 'flow of said charge only from the metering chamber to the expansion chamber.
  • a refrigeration unit comprising a case, a capsule of refrigerant, means for attaching said capsule to said case, means for tapping said capsule, a multiposition valve member movably fitted to said case, a metering chamber, ducting means leading from the tapping means to deliver a measured charge to the metering chamber when the valve member is in one position, an expansion chamber for the refrigerant, and ducting means leading from the metering chamber to release said measured charge to the expansion chamber when the valve is in a second position.
  • a portable refrigerating unit comprising a case to contain a detachable capsule of compressed refrigerant, means for tapping the capsule, a refrigerating head carried by and protruding from the case and movable inwardly of the case, a spring normally holding the head in pro truding position, means carried by the head to form a metering recess, means operated by motion of the head inwardly of the case to release a measured charge of compressed refrigerant into the metering recess, and a duct leading from the metering recess to the head to pass the measured charge from the metering recess and expand it into the head.
  • a refrigeration unit comprising a case having a cavity at one end, a capsule of compressed refrigerant, means for attaching the capsule to the case, means for tapping the capsule, a heat exchanger slidably fitted to the end cavity of the case and having a cooling surface projecting outside the case, a metering recess in the case capable of containing a specified amount of refrigerant, valving means operated by compression of the heat exchanger into the cavity to release a charge of refrigerant from the capsule to the metering recess, and ducting means for delivering the charge of refrigerant from the metering recess to .the heat exchanger.

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medical Informatics (AREA)
  • Otolaryngology (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
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  • Chemical & Material Sciences (AREA)
  • Combustion & Propulsion (AREA)
  • Physics & Mathematics (AREA)
  • Mechanical Engineering (AREA)
  • Thermal Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Thermotherapy And Cooling Therapy Devices (AREA)

Description

May 22, 1956 F. G. KEYES MINIATURE COOLING UNIT Filed July 17. 1953 INVENTOR. FREDERICK G. KEYES wzza ATTORNEYS United States Patent MINIATURE COOLING UNIT Frederick G. Keyes, Cambridge, Mass., assignor to Alfred Bicknell Associates, Inc., Cambridge, Mesa, 2 corporation of Massachusetts Application July 17, 1953, Serial No. 368,760
7 Claims. (Cl. 62-92) The present invention relates to a miniature refrigeration unit and in particular to a miniature portable refrigeration unit especially adapted for use in desensitizing skin regions in preparation for a hypodermic injection or the like.
Hypodermic injections may be made substantially painless by bringing the temperature of the skin surrounding the area of the injection down to a temperature between freezing and 40 degrees Fahrenheit. While devices exist which will freeze the skin for minor operations, such devices are not useful for this purpose since freezing the skin results in an increase in pain and sensation after the freezing wears off. If however the skin is chilled to a temperature just above the freezing point, then the procedure is effective to eliminate all sensation both during and after the injecting.
Accordingly, it is the object of this invention to provide a convenient and economical miniature refrigeration device which can be used quickly and conveniently to desensitize localized areas of the skin without freezing. More specifically, it is an object of the invention to provide a compact self-contained refrigeration unit, capable of hand-held operation, which may conveniently be operated to deliver a charge of refrigerant to a cooling surface in contact with the skin of the patient, so as to chill the selected skin area rapidly and effectively. It is a further object of this invention to provide such device which will use capsules of refrigerant in order to be completely portable and which will automatically meter the supply of refrigerant to the skin-contacting element as desired in amounts sufficient to effect the desired chilling without freezing.
Other objects and features of the invention will appear from the following description, taken in conjunction with the accompanying drawings in which Fig. 1 shows the external appearance of the device.
Fig. 2 is a sectional view taken along the major axis of the device on the line 2-2 of Fig. 1.
Fig. 3 is a sectional view on an enlarged scale of the lower end portion of the device shown in Figs. 1 and 2, showing the heat exchange chamber and contact cooling surface of the device, and
Fig. 4 is a cross-sectional view of the heat exchange chamber, taken on the line 4-4 of Fig. 3.
In Figs. 1 and 2 illustrating the preferred form of apparatus, the case 1 is made in four sections 2, 3, 4, and 5, which are attached together by overlapping threaded flanges. The cap 2 fitting over the body section 3 provides a chamber 9 containing a disposable metal capsule 7 of refrigerant. A hollow pointed needle 11 extends through the end of the refrigerant capsule and the capsule itself is firmly seated on the rubber ring 13 surrounding the needle. This needle extends downward into section 4 of the case to a small chamber 14 sealed by the O-ring 15. Refrigerant which passes through the hollow pointed needle into this chamber is filtered by the filter 19 which separates the chamber 14 from the passage 21 leading to the metering valve.
Patented May 22, 1956 While an ordinary needle valve would be usable, this construction is believed to provide greatly improved convenience and economy. This valve which automatically supplies the correct amount of refrigerant consists of a valve member which in this case is a spool 22 fitted so as to slide in a cylindrical chamber or cavity 20 in section 4 of the casing, and normally urged toward the head of the unit by a coil spring 24. A valve member of rectangular cross section would be equally acceptable, however. In this normal position passage of the refrigerant through the duct 21 is blocked by the flange 23 of this spool. Further sealing of the refrigerant is effected by the O-rings 25 and 26 on either side of the orifice leading to the duct 21. An escape duct 27 is provided through the case to the part of the cylindrical chamber containing the spring to prevent a building up of pressure by any refrigerant passing the O-ring 25.
The central part of the valve member is cut away to provide a recess forming a metering chamber 29 which may be loaded with refrigerant by forcing back the head of the instrument 50 causing the spool 22 to compress the spring 24 until this metering chamber is opposite the inlet port from the supply duct 21. In the normal position as shown, this metering chamber or recess leads to an outlet port supplying the delivery duct 31 in the case. This duct in turn leads to the annular groove 33 cut into the lower flange 32 of the spool 22 which opens to the delivery duct 37 carrying refrigerant to the cooling head 50 of the instrument. This lower flange is supplied with the O-rings 35 and 36 to prevent leakage. The delivery duct 37 is surrounded by an insulating member 38 which serves to minimize transfer of heat from the body of the instrument to the cooling head 54) and to firmly attach the exchanger 50 with the spool 22. Contact between this insulating member and the spool is further minimized by use of the washer 40.
The cooling head 50, construction of which will be more fully described presently is slidably fitted in the insulating member 41 which a protective sleeve preventing heat transfer between the cooling head 50 and the end section 5 of the case. Refrigerant which has expanded through the head 50 is permitted to escape through the outlet 43 in the insulating member and then through the outlet 45 in the case.
The cooling head 50 is shown in section in Fig. 3. It consists of a hollow cylindrical shell 53 having a relatively thick flat end plate 54 constructed of conductive material. The inside of this shell contains a spiral heat exchange chamber formed by a conductive vane 47 firmly attached to the end plate 54 and extending to but not attached to the opposite end of the chamber. The refrigerant line 57 through which the refrigerant is introduced to this chamber is an extension of the supply line 37 and is attached to the spiral vane. The refrigerant is released at the end and the expanding gas passes back along the spiral heat exchange chamber and the delivery line 57 to the outlet 60, which in turn leads to the exhaust port 43 described above. This use of the counterfiow principle in a spiral chamber enables all the expanding refrigerant to cool the incoming refrigerant in line 57 attached to the vane forming the spiral chamber. The fact that this vane is attached firmly on at the plate 54 provides maximum cooling of this surface while minimizing heat flow elsewhere.
Under normal conditions the spool valve and the head are maintained in extended position shown in Fig. 2 by means of the coil spring 24, and passage of refrigerant from the supply line 21 into the metering chamber is blocked. A capsule of liquid refrigerant is inserted in the case 3 and the cap 2 is tightened down over it thus forcing the capsule against the seal 13 and finally forcing the needle 11 to puncture the end of the capsule, thus releasing refrigerant through the screen 19 to the supply line 21. The liquid refrigerant in the capsule is maintained under pressure by the vapor of the refrigerant itself which has a boiling point below room temperature. The preferred refrigerant for this use is dichlorodifiuorornethane commonly known in the trade as Freon 12.
When the instrument is to be used, as, for example in anesthetizing a small area of a patients skin, the operator simply presses the head of the instrument 50 against a convenient surface, thus forcing the head and the spool back against the spring 24 and positioning the metering chamber 29 opposite the inlet port from the supply duct 21 whereupon a charge of refrigerant is admitted into the metering chamber. Pressure on the instrument is then released and the spring restores the parts to the position shown in Fig. 2 whereupon the refrigerant is released through the outlet port to the delivery line 31 and into the heat exchanging head 50. In passing through the heat exchange chamber described above, the refrigerant is vaporized and the vapor expands through this chamber thereby producing a rapid cooling effect both by absorption of the latent heat of vaporization and by expansion. The size of the metering chamber is such as to provide a quantity of refrigerant suflicient to cool the face of the instrument to a temperature of about 33 F.
It will be observed that this device is convenient to handle since the operator requires only one free hand and is economical since the metering chamber supplies only the amount of refrigerant actually needed. As heretofore noted it is particularly useful for mild local anesthesia for hypodermic injections. While the device has been described in terms of a single embodiment it will be understood that considerable variation in the actual construction may be made within the scope of this invention.
Having thus described my invention, I claim:
1. A refrigeration unit comprising a case, a detachable capsule of compressed refrigerant, means for tapping said capsule, valving means for periodically releasing a metered amount of the refrigerant, and a counterfiow heat exchanger for the refrigerant comprising a spiral chamber formed by a spiral vane attached to a flat cooling end surface wherein the refrigerant supply is carried through said spiral chamber in a duct attached to the vane and the expanding gas escaping through the spiral cools the incoming refrigerant.
2. A refrigeration unit comprising a case, a detachable capsule of refrigerant, means for tapping said capsule, a valve member slidably fitted to a chamber in the case and having a metering recess, said case having ducting means with an inlet port and an outlet port to the chamber separated by a distance greater than the length of the metering recess, spring loading means for maintaining the metering recess in registration with the outlet port, a heat exchanger comprising a single spiral expansion chamber for the refrigerant, ducting means connecting the tapping means with the inlet port and the outlet port with the heat exchanger, and means for positioning the metering recess opposite the inlet port.
3. A refrigeration unit comprising a case, a removable cap fitted to the case providing a chamber for a refrigerant capsule, a hollow needle surrounded by a compressible sealing member in said chamber and acting in cooperation with the cap to tap the capsule, a filtering member, a duct leading from the head of the needle to the filtering member, a multiposition valve .member slidably fitted to a chamber within the case, a metering storage recess, ducting means leading from the filter to the metering recess when the valve member is in one position, an expansion chamber for the refrigerant, and ducting means leading from the storage recess to the expansion chamber when the valve is in a second position.
4. A refrigeration unit comprising a case, a detachable capsule of refrigerant, means for tapping said capsule, a valve member movably fitted to a chamber within said case whereby a metering chamber for the refrigerant is formed between the valve member and a surface of said case chamber, an expansion chamber having a surface to be cooled, a supply duct'from the tapping means to an inlet port for the metering chamber, a delivery duct from an outlet port from the metering chamber to the expansion chamber, means for moving the valve member to effect flow of a charge from the inlet port to the metering chamber, and means for positioning the valve member to close the valve and permit 'flow of said charge only from the metering chamber to the expansion chamber.
5. A refrigeration unit comprising a case, a capsule of refrigerant, means for attaching said capsule to said case, means for tapping said capsule, a multiposition valve member movably fitted to said case, a metering chamber, ducting means leading from the tapping means to deliver a measured charge to the metering chamber when the valve member is in one position, an expansion chamber for the refrigerant, and ducting means leading from the metering chamber to release said measured charge to the expansion chamber when the valve is in a second position.
6..A portable refrigerating unit comprising a case to contain a detachable capsule of compressed refrigerant, means for tapping the capsule, a refrigerating head carried by and protruding from the case and movable inwardly of the case, a spring normally holding the head in pro truding position, means carried by the head to form a metering recess, means operated by motion of the head inwardly of the case to release a measured charge of compressed refrigerant into the metering recess, and a duct leading from the metering recess to the head to pass the measured charge from the metering recess and expand it into the head.
7. A refrigeration unit comprising a case having a cavity at one end, a capsule of compressed refrigerant, means for attaching the capsule to the case, means for tapping the capsule, a heat exchanger slidably fitted to the end cavity of the case and having a cooling surface projecting outside the case, a metering recess in the case capable of containing a specified amount of refrigerant, valving means operated by compression of the heat exchanger into the cavity to release a charge of refrigerant from the capsule to the metering recess, and ducting means for delivering the charge of refrigerant from the metering recess to .the heat exchanger.
References Cited in the file of this patent UNITED STATES PATENTS
US368760A 1953-07-17 1953-07-17 Miniature cooling unit Expired - Lifetime US2746264A (en)

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Cited By (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2786333A (en) * 1954-09-20 1957-03-26 Makara Frank Tire inflator
US2900808A (en) * 1955-11-22 1959-08-25 Wang Wensan Pocket liquid cooling device
US2982112A (en) * 1957-02-27 1961-05-02 Frederick G Keyes Inc Refrigeration apparatus for contact cooling of small areas
US3077085A (en) * 1960-05-27 1963-02-12 Johnston William Derrick Cooling unit for beverages
US3153685A (en) * 1960-09-29 1964-10-20 Gen Motors Corp Applying epoxy resin
US3298371A (en) * 1965-02-11 1967-01-17 Arnold S J Lee Freezing probe for the treatment of tissue, especially in neurosurgery
US3373581A (en) * 1966-08-31 1968-03-19 Wray Jr John Robert Container arrangement with coolant therein
US3399675A (en) * 1965-10-23 1968-09-03 Clifford W. Hill Hypodermic injector including a needle guide with pain desensitizing means
US3795245A (en) * 1971-04-29 1974-03-05 Al Co Du Splash-proof leak-proof syringe-type cryosurgical instrument
US4015591A (en) * 1976-02-17 1977-04-05 Liquid Crystal Products, Inc. Cholesteric liquid crystalline phase material-dye composition and venapuncture method employing the composition
US4022214A (en) * 1975-04-23 1977-05-10 Robert R. Schulze Method of treating substances in an ambient environment with a cryogenic material
US4074717A (en) * 1975-04-23 1978-02-21 Said Robert R. Schulze, By Said Floyd R. Ladd Cryogenic probe
EP0043447A2 (en) * 1980-06-13 1982-01-13 Karl-Heinz Kreibel Low-temperature transmission device for medical purposes
FR2486798A1 (en) * 1980-07-15 1982-01-22 Vyzk Ustav Silnoproude Elekt CRYOTHERAPY INSTRUMENT
US4602628A (en) * 1985-01-17 1986-07-29 Allen Jr Robert E Cryogenic extractor and filler
EP0198665A2 (en) * 1985-04-16 1986-10-22 Kidde-Graviner Limited Cooling apparatus
FR2602316A1 (en) * 1986-07-31 1988-02-05 Air Liquide JOULE-THOMSON COOLER, MANUFACTURING METHOD AND CRYOSTAT COMPRISING THE COOLER
US5200170A (en) * 1989-07-18 1993-04-06 Mcdow Ronald A Medical process--use of dichlorodifluoromethane (CCl2 F2) and chlorodifluoromethane (CHClF2) as cryogens for treating skin lesions
US5236419A (en) * 1992-12-11 1993-08-17 Seney John S Pain-alleviating device for injecting hypodermic needles
US5671648A (en) * 1996-01-16 1997-09-30 Dern; Klaus Rotary microtome with horizontal sweep
US20050182364A1 (en) * 2004-02-12 2005-08-18 Burchman Corey A. Ice pain management device and method
US20080015543A1 (en) * 2006-06-23 2008-01-17 Peng Wang Cold gas spray for stopping nosebleeds
EP1929981A1 (en) * 2006-12-07 2008-06-11 L'Oréal Cooling device
WO2008081444A2 (en) 2007-01-01 2008-07-10 Sindolor Medical Ltd A device and method for piercing a patient's skin with an injector whilst eliminating pain caused by the piercing
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EP0043447A2 (en) * 1980-06-13 1982-01-13 Karl-Heinz Kreibel Low-temperature transmission device for medical purposes
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US8083734B2 (en) * 2004-06-27 2011-12-27 Dieter Steinfatt Coolant dosing device
US20080306474A1 (en) * 2004-06-27 2008-12-11 Dieter Steinfatt Coolant Dosing Device for Finely Dosing Liquefied Crygenic Gas
US11793944B2 (en) 2006-03-07 2023-10-24 Vapocoolshot, Inc. Method and apparatus for applying an anesthetic and bactericide
US10004855B2 (en) 2006-03-07 2018-06-26 Leibovici Llc Method and apparatus for applying an anesthetic and bactericide
US9656028B2 (en) 2006-03-07 2017-05-23 Leibovici Llc Method and apparatus for applying an anesthetic and batericide
US20080015543A1 (en) * 2006-06-23 2008-01-17 Peng Wang Cold gas spray for stopping nosebleeds
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US7832225B2 (en) 2006-12-07 2010-11-16 L'oreal Body surface cooling device and method for application of cosmetics
EP1929981A1 (en) * 2006-12-07 2008-06-11 L'Oréal Cooling device
FR2909544A1 (en) * 2006-12-07 2008-06-13 Oreal COOLING DEVICE
US20100049126A1 (en) * 2007-01-01 2010-02-25 Sindolor Medical Ltd. Device and method for piercing a patient's skin with an injector whilst reducing pain caused by the piercing
WO2008081444A2 (en) 2007-01-01 2008-07-10 Sindolor Medical Ltd A device and method for piercing a patient's skin with an injector whilst eliminating pain caused by the piercing
US20100106088A1 (en) * 2007-06-25 2010-04-29 Ofer Yodfat Portable infusion pump with cannula inserter and pain reduction mechanism
WO2009001347A1 (en) 2007-06-25 2008-12-31 Medingo Ltd. Portable infusion pump with cannula inserter and pain reduction mechanism
US8715232B2 (en) 2007-06-25 2014-05-06 Roche Diagnostics Operations Inc. Portable infusion pump with cannula inserter and pain reduction mechanism
US20090062783A1 (en) * 2007-08-28 2009-03-05 Sun William Y Ice tip hypodermic needle
US20090062737A1 (en) * 2007-08-28 2009-03-05 Sun William Y Ice coated hypodermic needle
US20090254158A1 (en) * 2008-04-04 2009-10-08 Oleg Shapiro Cooling device for locally anesthetizing an area on the surface of the body
US8177827B2 (en) * 2008-04-04 2012-05-15 Oleg Shapiro Cooling device for locally anesthetizing an area on the surface of the body
US9398975B2 (en) 2010-04-15 2016-07-26 Stefan Müller Hand-operated cooling device for cryotherapy
WO2011141243A1 (en) * 2010-04-15 2011-11-17 Mueller Stefan Hand-operated cooling device for cryotherapy
US9017318B2 (en) * 2012-01-20 2015-04-28 Myoscience, Inc. Cryogenic probe system and method
US20130190745A1 (en) * 2012-01-20 2013-07-25 Myoscience, Inc. Cryogenic Probe System
CN107809978A (en) * 2015-05-04 2018-03-16 牡蛎壳公司 For treating dermopathic pen and its application method
US20180140344A1 (en) * 2015-05-04 2018-05-24 Oystershell Nv Pen for the treatment of dermatological disorders and method for use thereof
US11376056B2 (en) * 2015-05-04 2022-07-05 Oystershell Nv Pen for the treatment of dermatological disorders and method for use thereof
USD820972S1 (en) * 2016-12-20 2018-06-19 Pronova Laboratories B.V. Wart freezing device
EP3457051A1 (en) * 2017-09-18 2019-03-20 The Boeing Company An apparatus for heat transfer, utilizing the joules-thomson effect
CN109520168A (en) * 2017-09-18 2019-03-26 波音公司 Establish the device that hot transmitting is carried out using Joule-Thomson (JT) effect on heat generating device
US10914495B2 (en) 2017-09-18 2021-02-09 The Boeing Company Apparatus for heat transfer, utilizing the Joule Thomson (JT) effect, for crowning upon heat-emitting devices
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